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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:UBE2L3-APOL1 (FusionGDB2 ID:96164)

Fusion Gene Summary for UBE2L3-APOL1

check button Fusion gene summary
Fusion gene informationFusion gene name: UBE2L3-APOL1
Fusion gene ID: 96164
HgeneTgene
Gene symbol

UBE2L3

APOL1

Gene ID

7332

8542

Gene nameubiquitin conjugating enzyme E2 L3apolipoprotein L1
SynonymsE2-F1|L-UBC|UBCH7|UbcM4APO-L|APOL|APOL-I|FSGS4
Cytomap

22q11.21

22q12.3

Type of geneprotein-codingprotein-coding
Descriptionubiquitin-conjugating enzyme E2 L3E2 ubiquitin-conjugating enzyme L3ubiquitin carrier protein L3ubiquitin conjugating enzyme E2L 3ubiquitin-conjugating enzyme E2-F1ubiquitin-conjugating enzyme UBCH7ubiquitin-protein ligase L3apolipoprotein L1apolipoprotein L 1apolipoprotein L1-B3
Modification date2020031320200329
UniProtAcc.

O14791

Ensembl transtripts involved in fusion geneENST00000342192, ENST00000458578, 
ENST00000545681, 		ENST00000347595, 
ENST00000397279, ENST00000440669, 
ENST00000319136, ENST00000397278, 
ENST00000422706, ENST00000426053, 
Fusion gene scores* DoF score9 X 6 X 8=4322 X 2 X 2=8
# samples 122
** MAII scorelog2(12/432*10)=-1.84799690655495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(2/8*10)=1.32192809488736
Context

PubMed: UBE2L3 [Title/Abstract] AND APOL1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointUBE2L3(21965332)-APOL1(36657642), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneUBE2L3

GO:0000209

protein polyubiquitination

10888878|14765125

HgeneUBE2L3

GO:0006355

regulation of transcription, DNA-templated

17003263

HgeneUBE2L3

GO:0016567

protein ubiquitination

9990509|21532592

HgeneUBE2L3

GO:0070979

protein K11-linked ubiquitination

20061386

HgeneUBE2L3

GO:0071385

cellular response to glucocorticoid stimulus

17003263

TgeneAPOL1

GO:0045087

innate immune response

17192540

TgeneAPOL1

GO:0051838

cytolysis by host of symbiont cells

12621437|17192540

TgeneAPOL1

GO:1902476

chloride transmembrane transport

16020735


check buttonFusion gene breakpoints across UBE2L3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across APOL1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4UCSTCGA-N5-A4RA-01AUBE2L3chr22

21965332

+APOL1chr22

36657642

+
ChimerDB4UCSTCGA-N5-A4RAUBE2L3chr22

21965332

+APOL1chr22

36657642

+


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Fusion Gene ORF analysis for UBE2L3-APOL1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000342192ENST00000347595UBE2L3chr22

21965332

+APOL1chr22

36657642

+
5CDS-5UTRENST00000342192ENST00000397279UBE2L3chr22

21965332

+APOL1chr22

36657642

+
5CDS-5UTRENST00000342192ENST00000440669UBE2L3chr22

21965332

+APOL1chr22

36657642

+
5CDS-5UTRENST00000458578ENST00000347595UBE2L3chr22

21965332

+APOL1chr22

36657642

+
5CDS-5UTRENST00000458578ENST00000397279UBE2L3chr22

21965332

+APOL1chr22

36657642

+
5CDS-5UTRENST00000458578ENST00000440669UBE2L3chr22

21965332

+APOL1chr22

36657642

+
5CDS-5UTRENST00000545681ENST00000347595UBE2L3chr22

21965332

+APOL1chr22

36657642

+
5CDS-5UTRENST00000545681ENST00000397279UBE2L3chr22

21965332

+APOL1chr22

36657642

+
5CDS-5UTRENST00000545681ENST00000440669UBE2L3chr22

21965332

+APOL1chr22

36657642

+
In-frameENST00000342192ENST00000319136UBE2L3chr22

21965332

+APOL1chr22

36657642

+
In-frameENST00000342192ENST00000397278UBE2L3chr22

21965332

+APOL1chr22

36657642

+
In-frameENST00000342192ENST00000422706UBE2L3chr22

21965332

+APOL1chr22

36657642

+
In-frameENST00000342192ENST00000426053UBE2L3chr22

21965332

+APOL1chr22

36657642

+
In-frameENST00000458578ENST00000319136UBE2L3chr22

21965332

+APOL1chr22

36657642

+
In-frameENST00000458578ENST00000397278UBE2L3chr22

21965332

+APOL1chr22

36657642

+
In-frameENST00000458578ENST00000422706UBE2L3chr22

21965332

+APOL1chr22

36657642

+
In-frameENST00000458578ENST00000426053UBE2L3chr22

21965332

+APOL1chr22

36657642

+
In-frameENST00000545681ENST00000319136UBE2L3chr22

21965332

+APOL1chr22

36657642

+
In-frameENST00000545681ENST00000397278UBE2L3chr22

21965332

+APOL1chr22

36657642

+
In-frameENST00000545681ENST00000422706UBE2L3chr22

21965332

+APOL1chr22

36657642

+
In-frameENST00000545681ENST00000426053UBE2L3chr22

21965332

+APOL1chr22

36657642

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000458578UBE2L3chr2221965332+ENST00000397278APOL1chr2236657642+298948731496497
ENST00000458578UBE2L3chr2221965332+ENST00000426053APOL1chr2236657642+299448731496497
ENST00000458578UBE2L3chr2221965332+ENST00000422706APOL1chr2236657642+299448731496497
ENST00000458578UBE2L3chr2221965332+ENST00000319136APOL1chr2236657642+298548731496497
ENST00000342192UBE2L3chr2221965332+ENST00000397278APOL1chr2236657642+3010508301517495
ENST00000342192UBE2L3chr2221965332+ENST00000426053APOL1chr2236657642+3015508301517495
ENST00000342192UBE2L3chr2221965332+ENST00000422706APOL1chr2236657642+3015508301517495
ENST00000342192UBE2L3chr2221965332+ENST00000319136APOL1chr2236657642+3006508301517495
ENST00000545681UBE2L3chr2221965332+ENST00000397278APOL1chr2236657642+272422281231407
ENST00000545681UBE2L3chr2221965332+ENST00000426053APOL1chr2236657642+272922281231407
ENST00000545681UBE2L3chr2221965332+ENST00000422706APOL1chr2236657642+272922281231407
ENST00000545681UBE2L3chr2221965332+ENST00000319136APOL1chr2236657642+272022281231407

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000458578ENST00000397278UBE2L3chr2221965332+APOL1chr2236657642+0.0026608030.9973392
ENST00000458578ENST00000426053UBE2L3chr2221965332+APOL1chr2236657642+0.0027286460.99727136
ENST00000458578ENST00000422706UBE2L3chr2221965332+APOL1chr2236657642+0.0027286460.99727136
ENST00000458578ENST00000319136UBE2L3chr2221965332+APOL1chr2236657642+0.0026555720.99734443
ENST00000342192ENST00000397278UBE2L3chr2221965332+APOL1chr2236657642+0.0032459760.996754
ENST00000342192ENST00000426053UBE2L3chr2221965332+APOL1chr2236657642+0.0033366530.9966633
ENST00000342192ENST00000422706UBE2L3chr2221965332+APOL1chr2236657642+0.0033366530.9966633
ENST00000342192ENST00000319136UBE2L3chr2221965332+APOL1chr2236657642+0.0032604390.99673957
ENST00000545681ENST00000397278UBE2L3chr2221965332+APOL1chr2236657642+0.0043012630.9956988
ENST00000545681ENST00000426053UBE2L3chr2221965332+APOL1chr2236657642+0.0044179060.99558204
ENST00000545681ENST00000422706UBE2L3chr2221965332+APOL1chr2236657642+0.0044179060.99558204
ENST00000545681ENST00000319136UBE2L3chr2221965332+APOL1chr2236657642+0.0042646250.9957354

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Fusion Genomic Features for UBE2L3-APOL1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
UBE2L3chr2221965332+APOL1chr2236657641+2.69E-070.99999976
UBE2L3chr2221965332+APOL1chr2236657641+2.69E-070.99999976
UBE2L3chr2221965332+APOL1chr2236657641+2.69E-070.99999976
UBE2L3chr2221965332+APOL1chr2236657641+2.69E-070.99999976

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for UBE2L3-APOL1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr22:21965332/chr22:36657642)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.APOL1

O14791

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: May play a role in lipid exchange and transport throughout the body. May participate in reverse cholesterol transport from peripheral cells to the liver.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneUBE2L3chr22:21965332chr22:36657642ENST00000458578+342_149161213.0DomainUBC core

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneUBE2L3chr22:21965332chr22:36657642ENST00000342192+342_149103155.0DomainUBC core
HgeneUBE2L3chr22:21965332chr22:36657642ENST00000545681+232_14971123.0DomainUBC core


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Fusion Gene Sequence for UBE2L3-APOL1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>96164_96164_1_UBE2L3-APOL1_UBE2L3_chr22_21965332_ENST00000342192_APOL1_chr22_36657642_ENST00000319136_length(transcript)=3006nt_BP=508nt
AAACGCTGAGGCCCAGTCTGTGCGGTTCACTTGCGTTCCTCCACGCGCCCCCCAGCACAGTGGGAAGCACACAGTAGGTGCTCCGCTCTG
CTCCTGTGCCCCGCCCCGCGGCCCCTCCCCCGCTCCAGGAAGTGCGGGGGCTCCAGCCGCCCGGCCGGCCGCGATGCATTCTGGGGAAGG
AGCAGCACCAAATCCAAGATGGCGGCCAGCAGGAGGCTGATGAAGGAGCTTGAAGAAATCCGCAAATGTGGGATGAAAAACTTCCGTAAC
ATCCAGGTTGATGAAGCTAATTTATTGACTTGGCAAGGGCTTATTGTTCCTGACAACCCTCCATATGATAAGGGAGCCTTCAGAATCGAA
ATCAACTTTCCAGCAGAGTACCCATTCAAACCACCGAAGATCACATTTAAAACAAAGATCTATCACCCAAACATCGACGAAAAGGGGCAG
GTCTGTCTGCCAGTAATTAGTGCCGAAAACTGGAAGCCAGCAACCAAAACCGACCAAGAGAGCAGTATCTTTATTGAGGATGCCATTAAG
TATTTCAAGGAAAAAGTGAGCACACAGAATCTGCTACTCCTGCTGACTGATAATGAGGCCTGGAACGGATTCGTGGCTGCTGCTGAACTG
CCCAGGAATGAGGCAGATGAGCTCCGTAAAGCTCTGGACAACCTTGCAAGACAAATGATCATGAAAGACAAAAACTGGCACGATAAAGGC
CAGCAGTACAGAAACTGGTTTCTGAAAGAGTTTCCTCGGTTGAAAAGTGAGCTTGAGGATAACATAAGAAGGCTCCGTGCCCTTGCAGAT
GGGGTTCAGAAGGTCCACAAAGGCACCACCATCGCCAATGTGGTGTCTGGCTCTCTCAGCATTTCCTCTGGCATCCTGACCCTCGTCGGC
ATGGGTCTGGCACCCTTCACAGAGGGAGGCAGCCTTGTACTCTTGGAACCTGGGATGGAGTTGGGAATCACAGCCGCTTTGACCGGGATT
ACCAGCAGTACCATGGACTACGGAAAGAAGTGGTGGACACAAGCCCAAGCCCACGACCTGGTCATCAAAAGCCTTGACAAATTGAAGGAG
GTGAGGGAGTTTTTGGGTGAGAACATATCCAACTTTCTTTCCTTAGCTGGCAATACTTACCAACTCACACGAGGCATTGGGAAGGACATC
CGTGCCCTCAGACGAGCCAGAGCCAATCTTCAGTCAGTACCGCATGCCTCAGCCTCACGCCCCCGGGTCACTGAGCCAATCTCAGCTGAA
AGCGGTGAACAGGTGGAGAGGGTTAATGAACCCAGCATCCTGGAAATGAGCAGAGGAGTCAAGCTCACGGATGTGGCCCCTGTAAGCTTC
TTTCTTGTGCTGGATGTAGTCTACCTCGTGTACGAATCAAAGCACTTACATGAGGGGGCAAAGTCAGAGACAGCTGAGGAGCTGAAGAAG
GTGGCTCAGGAGCTGGAGGAGAAGCTAAACATTCTCAACAATAATTATAAGATTCTGCAGGCGGACCAAGAACTGTGACCACAGGGCAGG
GCAGCCACCAGGAGAGATATGCCTGGCAGGGGCCAGGACAAAATGCAAACTTTTTTTTTTTTCTGAGACAGAGTCTTGCTCTGTCGCCAA
GTTGGAGTGCAATGGTGCGATCTCAGCTCACTGCAAGCTCTGCCTCCCGTGTTCAAGCGATTCTCCTGCCTTGGCCTCCCAAGTAGCTGG
GACTACAGGCGCCTACCACCATGCCCAGCTAATTTTTGTATTTTTAATAGAGATGGGGTTTCACCATGTTGGCCAGGATGGTCTCGATCT
CCTGACCTCTTGATCTGCCCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCATCGCTTTTGACCCAAATGCAAACATTTTA
TTAGGGGGATAAAGAGGGTGAGGTAAAGTTTATGGAACTGAGTGTTAGGGACTTTGGCATTTCCATAGCTGAGCACAGCAGGGGAGGGGT
TAATGCAGATGGCAGTGCAGCAAGGAGAAGGCAGGAACATTGGAGCCTGCAATAAGGGAAAAATGGGAACTGGAGAGTGTGGGGAATGGG
AAGAAGCAGTTTACTTTAGACTAAAGAATATATTGGGGGGCCGGGTGTAGTGGCTCATGCCTGTAATCCGAGCACTTTGGGAGGCCAAGG
CGGGCGGATCACGAGGTCAGGAGATCGAGACCATCCTGGCTAACACAGTGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCCGGGC
ATGGTGGCGGGCGCCTGTAGTTCCAGCTAACTGGGCGGCTGAGGCAGGAGAATGGCGTGAACCTGGGAGGTGGAGCTTGCAGTGAGCCGA
GATATCGCCACTGCACTCCAGCCTGGGTGACAGAGCGAGACTCCATCTCAAAAAAAAAAAAAAAAAGAATATATTGACGGAAGAATAGAG
AGGAGGCTTGAAGGAACCAGCAATGAGAAGGCCAGGAAAAGAAAGAGCTGAAAATGGAGAAAGCCCAAGAGTTAGAACAGTTGGATACAG
GAGAAGAAACAGCGGCTCCACTACAGACCCAGCCCCAGGTTCAATGTCCTCCGAAGAATGAAGTCTTTCCCTGGTGATGGTCCCCTGCCC
TGTCTTTCCAGCATCCACTCTCCCTTGTCCTCCTGGGGGCATATCTCAGTCAGGCAGCGGCTTCCTGATGATGGTCATTGGGGTGGTTGT
CATGTGATGGGTCCCCTCCAGGTTACTAAAGGGTGCATGTCCCCTGCTTGAACACTGAAGGGCAGGTGGTGGGCCATGGCCATGGTCCCC
AGCTGAGGAGCAGGTGTCCCTGAGAACCCAAACTTCCCAGAGAGTATGTGAGAACCAACCAATGAAAACAGTCCCATCGCTCTTACCCGG
TAAGTAAACAGTCAGAAAATTAGCATGAAAGCAGTTTAGCATTGGGAGGAAGCTCAGATCTCTAGAGCTGTCTTGTCGCCGCCCAGGATT

>96164_96164_1_UBE2L3-APOL1_UBE2L3_chr22_21965332_ENST00000342192_APOL1_chr22_36657642_ENST00000319136_length(amino acids)=495AA_BP=146
MRSSTRPPAQWEAHSRCSALLLCPAPRPLPRSRKCGGSSRPAGRDAFWGRSSTKSKMAASRRLMKELEEIRKCGMKNFRNIQVDEANLLT
WQGLIVPDNPPYDKGAFRIEINFPAEYPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQESSIFIEDAIKYFKEKVSTQN
LLLLLTDNEAWNGFVAAAELPRNEADELRKALDNLARQMIMKDKNWHDKGQQYRNWFLKEFPRLKSELEDNIRRLRALADGVQKVHKGTT
IANVVSGSLSISSGILTLVGMGLAPFTEGGSLVLLEPGMELGITAALTGITSSTMDYGKKWWTQAQAHDLVIKSLDKLKEVREFLGENIS
NFLSLAGNTYQLTRGIGKDIRALRRARANLQSVPHASASRPRVTEPISAESGEQVERVNEPSILEMSRGVKLTDVAPVSFFLVLDVVYLV

--------------------------------------------------------------
>96164_96164_2_UBE2L3-APOL1_UBE2L3_chr22_21965332_ENST00000342192_APOL1_chr22_36657642_ENST00000397278_length(transcript)=3010nt_BP=508nt
AAACGCTGAGGCCCAGTCTGTGCGGTTCACTTGCGTTCCTCCACGCGCCCCCCAGCACAGTGGGAAGCACACAGTAGGTGCTCCGCTCTG
CTCCTGTGCCCCGCCCCGCGGCCCCTCCCCCGCTCCAGGAAGTGCGGGGGCTCCAGCCGCCCGGCCGGCCGCGATGCATTCTGGGGAAGG
AGCAGCACCAAATCCAAGATGGCGGCCAGCAGGAGGCTGATGAAGGAGCTTGAAGAAATCCGCAAATGTGGGATGAAAAACTTCCGTAAC
ATCCAGGTTGATGAAGCTAATTTATTGACTTGGCAAGGGCTTATTGTTCCTGACAACCCTCCATATGATAAGGGAGCCTTCAGAATCGAA
ATCAACTTTCCAGCAGAGTACCCATTCAAACCACCGAAGATCACATTTAAAACAAAGATCTATCACCCAAACATCGACGAAAAGGGGCAG
GTCTGTCTGCCAGTAATTAGTGCCGAAAACTGGAAGCCAGCAACCAAAACCGACCAAGAGAGCAGTATCTTTATTGAGGATGCCATTAAG
TATTTCAAGGAAAAAGTGAGCACACAGAATCTGCTACTCCTGCTGACTGATAATGAGGCCTGGAACGGATTCGTGGCTGCTGCTGAACTG
CCCAGGAATGAGGCAGATGAGCTCCGTAAAGCTCTGGACAACCTTGCAAGACAAATGATCATGAAAGACAAAAACTGGCACGATAAAGGC
CAGCAGTACAGAAACTGGTTTCTGAAAGAGTTTCCTCGGTTGAAAAGTGAGCTTGAGGATAACATAAGAAGGCTCCGTGCCCTTGCAGAT
GGGGTTCAGAAGGTCCACAAAGGCACCACCATCGCCAATGTGGTGTCTGGCTCTCTCAGCATTTCCTCTGGCATCCTGACCCTCGTCGGC
ATGGGTCTGGCACCCTTCACAGAGGGAGGCAGCCTTGTACTCTTGGAACCTGGGATGGAGTTGGGAATCACAGCCGCTTTGACCGGGATT
ACCAGCAGTACCATGGACTACGGAAAGAAGTGGTGGACACAAGCCCAAGCCCACGACCTGGTCATCAAAAGCCTTGACAAATTGAAGGAG
GTGAGGGAGTTTTTGGGTGAGAACATATCCAACTTTCTTTCCTTAGCTGGCAATACTTACCAACTCACACGAGGCATTGGGAAGGACATC
CGTGCCCTCAGACGAGCCAGAGCCAATCTTCAGTCAGTACCGCATGCCTCAGCCTCACGCCCCCGGGTCACTGAGCCAATCTCAGCTGAA
AGCGGTGAACAGGTGGAGAGGGTTAATGAACCCAGCATCCTGGAAATGAGCAGAGGAGTCAAGCTCACGGATGTGGCCCCTGTAAGCTTC
TTTCTTGTGCTGGATGTAGTCTACCTCGTGTACGAATCAAAGCACTTACATGAGGGGGCAAAGTCAGAGACAGCTGAGGAGCTGAAGAAG
GTGGCTCAGGAGCTGGAGGAGAAGCTAAACATTCTCAACAATAATTATAAGATTCTGCAGGCGGACCAAGAACTGTGACCACAGGGCAGG
GCAGCCACCAGGAGAGATATGCCTGGCAGGGGCCAGGACAAAATGCAAACTTTTTTTTTTTTCTGAGACAGAGTCTTGCTCTGTCGCCAA
GTTGGAGTGCAATGGTGCGATCTCAGCTCACTGCAAGCTCTGCCTCCCGTGTTCAAGCGATTCTCCTGCCTTGGCCTCCCAAGTAGCTGG
GACTACAGGCGCCTACCACCATGCCCAGCTAATTTTTGTATTTTTAATAGAGATGGGGTTTCACCATGTTGGCCAGGATGGTCTCGATCT
CCTGACCTCTTGATCTGCCCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCATCGCTTTTGACCCAAATGCAAACATTTTA
TTAGGGGGATAAAGAGGGTGAGGTAAAGTTTATGGAACTGAGTGTTAGGGACTTTGGCATTTCCATAGCTGAGCACAGCAGGGGAGGGGT
TAATGCAGATGGCAGTGCAGCAAGGAGAAGGCAGGAACATTGGAGCCTGCAATAAGGGAAAAATGGGAACTGGAGAGTGTGGGGAATGGG
AAGAAGCAGTTTACTTTAGACTAAAGAATATATTGGGGGGCCGGGTGTAGTGGCTCATGCCTGTAATCCGAGCACTTTGGGAGGCCAAGG
CGGGCGGATCACGAGGTCAGGAGATCGAGACCATCCTGGCTAACACAGTGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCCGGGC
ATGGTGGCGGGCGCCTGTAGTTCCAGCTAACTGGGCGGCTGAGGCAGGAGAATGGCGTGAACCTGGGAGGTGGAGCTTGCAGTGAGCCGA
GATATCGCCACTGCACTCCAGCCTGGGTGACAGAGCGAGACTCCATCTCAAAAAAAAAAAAAAAAAGAATATATTGACGGAAGAATAGAG
AGGAGGCTTGAAGGAACCAGCAATGAGAAGGCCAGGAAAAGAAAGAGCTGAAAATGGAGAAAGCCCAAGAGTTAGAACAGTTGGATACAG
GAGAAGAAACAGCGGCTCCACTACAGACCCAGCCCCAGGTTCAATGTCCTCCGAAGAATGAAGTCTTTCCCTGGTGATGGTCCCCTGCCC
TGTCTTTCCAGCATCCACTCTCCCTTGTCCTCCTGGGGGCATATCTCAGTCAGGCAGCGGCTTCCTGATGATGGTCATTGGGGTGGTTGT
CATGTGATGGGTCCCCTCCAGGTTACTAAAGGGTGCATGTCCCCTGCTTGAACACTGAAGGGCAGGTGGTGGGCCATGGCCATGGTCCCC
AGCTGAGGAGCAGGTGTCCCTGAGAACCCAAACTTCCCAGAGAGTATGTGAGAACCAACCAATGAAAACAGTCCCATCGCTCTTACCCGG
TAAGTAAACAGTCAGAAAATTAGCATGAAAGCAGTTTAGCATTGGGAGGAAGCTCAGATCTCTAGAGCTGTCTTGTCGCCGCCCAGGATT

>96164_96164_2_UBE2L3-APOL1_UBE2L3_chr22_21965332_ENST00000342192_APOL1_chr22_36657642_ENST00000397278_length(amino acids)=495AA_BP=146
MRSSTRPPAQWEAHSRCSALLLCPAPRPLPRSRKCGGSSRPAGRDAFWGRSSTKSKMAASRRLMKELEEIRKCGMKNFRNIQVDEANLLT
WQGLIVPDNPPYDKGAFRIEINFPAEYPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQESSIFIEDAIKYFKEKVSTQN
LLLLLTDNEAWNGFVAAAELPRNEADELRKALDNLARQMIMKDKNWHDKGQQYRNWFLKEFPRLKSELEDNIRRLRALADGVQKVHKGTT
IANVVSGSLSISSGILTLVGMGLAPFTEGGSLVLLEPGMELGITAALTGITSSTMDYGKKWWTQAQAHDLVIKSLDKLKEVREFLGENIS
NFLSLAGNTYQLTRGIGKDIRALRRARANLQSVPHASASRPRVTEPISAESGEQVERVNEPSILEMSRGVKLTDVAPVSFFLVLDVVYLV

--------------------------------------------------------------
>96164_96164_3_UBE2L3-APOL1_UBE2L3_chr22_21965332_ENST00000342192_APOL1_chr22_36657642_ENST00000422706_length(transcript)=3015nt_BP=508nt
AAACGCTGAGGCCCAGTCTGTGCGGTTCACTTGCGTTCCTCCACGCGCCCCCCAGCACAGTGGGAAGCACACAGTAGGTGCTCCGCTCTG
CTCCTGTGCCCCGCCCCGCGGCCCCTCCCCCGCTCCAGGAAGTGCGGGGGCTCCAGCCGCCCGGCCGGCCGCGATGCATTCTGGGGAAGG
AGCAGCACCAAATCCAAGATGGCGGCCAGCAGGAGGCTGATGAAGGAGCTTGAAGAAATCCGCAAATGTGGGATGAAAAACTTCCGTAAC
ATCCAGGTTGATGAAGCTAATTTATTGACTTGGCAAGGGCTTATTGTTCCTGACAACCCTCCATATGATAAGGGAGCCTTCAGAATCGAA
ATCAACTTTCCAGCAGAGTACCCATTCAAACCACCGAAGATCACATTTAAAACAAAGATCTATCACCCAAACATCGACGAAAAGGGGCAG
GTCTGTCTGCCAGTAATTAGTGCCGAAAACTGGAAGCCAGCAACCAAAACCGACCAAGAGAGCAGTATCTTTATTGAGGATGCCATTAAG
TATTTCAAGGAAAAAGTGAGCACACAGAATCTGCTACTCCTGCTGACTGATAATGAGGCCTGGAACGGATTCGTGGCTGCTGCTGAACTG
CCCAGGAATGAGGCAGATGAGCTCCGTAAAGCTCTGGACAACCTTGCAAGACAAATGATCATGAAAGACAAAAACTGGCACGATAAAGGC
CAGCAGTACAGAAACTGGTTTCTGAAAGAGTTTCCTCGGTTGAAAAGTGAGCTTGAGGATAACATAAGAAGGCTCCGTGCCCTTGCAGAT
GGGGTTCAGAAGGTCCACAAAGGCACCACCATCGCCAATGTGGTGTCTGGCTCTCTCAGCATTTCCTCTGGCATCCTGACCCTCGTCGGC
ATGGGTCTGGCACCCTTCACAGAGGGAGGCAGCCTTGTACTCTTGGAACCTGGGATGGAGTTGGGAATCACAGCCGCTTTGACCGGGATT
ACCAGCAGTACCATGGACTACGGAAAGAAGTGGTGGACACAAGCCCAAGCCCACGACCTGGTCATCAAAAGCCTTGACAAATTGAAGGAG
GTGAGGGAGTTTTTGGGTGAGAACATATCCAACTTTCTTTCCTTAGCTGGCAATACTTACCAACTCACACGAGGCATTGGGAAGGACATC
CGTGCCCTCAGACGAGCCAGAGCCAATCTTCAGTCAGTACCGCATGCCTCAGCCTCACGCCCCCGGGTCACTGAGCCAATCTCAGCTGAA
AGCGGTGAACAGGTGGAGAGGGTTAATGAACCCAGCATCCTGGAAATGAGCAGAGGAGTCAAGCTCACGGATGTGGCCCCTGTAAGCTTC
TTTCTTGTGCTGGATGTAGTCTACCTCGTGTACGAATCAAAGCACTTACATGAGGGGGCAAAGTCAGAGACAGCTGAGGAGCTGAAGAAG
GTGGCTCAGGAGCTGGAGGAGAAGCTAAACATTCTCAACAATAATTATAAGATTCTGCAGGCGGACCAAGAACTGTGACCACAGGGCAGG
GCAGCCACCAGGAGAGATATGCCTGGCAGGGGCCAGGACAAAATGCAAACTTTTTTTTTTTTCTGAGACAGAGTCTTGCTCTGTCGCCAA
GTTGGAGTGCAATGGTGCGATCTCAGCTCACTGCAAGCTCTGCCTCCCGTGTTCAAGCGATTCTCCTGCCTTGGCCTCCCAAGTAGCTGG
GACTACAGGCGCCTACCACCATGCCCAGCTAATTTTTGTATTTTTAATAGAGATGGGGTTTCACCATGTTGGCCAGGATGGTCTCGATCT
CCTGACCTCTTGATCTGCCCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCATCGCTTTTGACCCAAATGCAAACATTTTA
TTAGGGGGATAAAGAGGGTGAGGTAAAGTTTATGGAACTGAGTGTTAGGGACTTTGGCATTTCCATAGCTGAGCACAGCAGGGGAGGGGT
TAATGCAGATGGCAGTGCAGCAAGGAGAAGGCAGGAACATTGGAGCCTGCAATAAGGGAAAAATGGGAACTGGAGAGTGTGGGGAATGGG
AAGAAGCAGTTTACTTTAGACTAAAGAATATATTGGGGGGCCGGGTGTAGTGGCTCATGCCTGTAATCCGAGCACTTTGGGAGGCCAAGG
CGGGCGGATCACGAGGTCAGGAGATCGAGACCATCCTGGCTAACACAGTGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCCGGGC
ATGGTGGCGGGCGCCTGTAGTTCCAGCTAACTGGGCGGCTGAGGCAGGAGAATGGCGTGAACCTGGGAGGTGGAGCTTGCAGTGAGCCGA
GATATCGCCACTGCACTCCAGCCTGGGTGACAGAGCGAGACTCCATCTCAAAAAAAAAAAAAAAAAGAATATATTGACGGAAGAATAGAG
AGGAGGCTTGAAGGAACCAGCAATGAGAAGGCCAGGAAAAGAAAGAGCTGAAAATGGAGAAAGCCCAAGAGTTAGAACAGTTGGATACAG
GAGAAGAAACAGCGGCTCCACTACAGACCCAGCCCCAGGTTCAATGTCCTCCGAAGAATGAAGTCTTTCCCTGGTGATGGTCCCCTGCCC
TGTCTTTCCAGCATCCACTCTCCCTTGTCCTCCTGGGGGCATATCTCAGTCAGGCAGCGGCTTCCTGATGATGGTCATTGGGGTGGTTGT
CATGTGATGGGTCCCCTCCAGGTTACTAAAGGGTGCATGTCCCCTGCTTGAACACTGAAGGGCAGGTGGTGGGCCATGGCCATGGTCCCC
AGCTGAGGAGCAGGTGTCCCTGAGAACCCAAACTTCCCAGAGAGTATGTGAGAACCAACCAATGAAAACAGTCCCATCGCTCTTACCCGG
TAAGTAAACAGTCAGAAAATTAGCATGAAAGCAGTTTAGCATTGGGAGGAAGCTCAGATCTCTAGAGCTGTCTTGTCGCCGCCCAGGATT

>96164_96164_3_UBE2L3-APOL1_UBE2L3_chr22_21965332_ENST00000342192_APOL1_chr22_36657642_ENST00000422706_length(amino acids)=495AA_BP=146
MRSSTRPPAQWEAHSRCSALLLCPAPRPLPRSRKCGGSSRPAGRDAFWGRSSTKSKMAASRRLMKELEEIRKCGMKNFRNIQVDEANLLT
WQGLIVPDNPPYDKGAFRIEINFPAEYPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQESSIFIEDAIKYFKEKVSTQN
LLLLLTDNEAWNGFVAAAELPRNEADELRKALDNLARQMIMKDKNWHDKGQQYRNWFLKEFPRLKSELEDNIRRLRALADGVQKVHKGTT
IANVVSGSLSISSGILTLVGMGLAPFTEGGSLVLLEPGMELGITAALTGITSSTMDYGKKWWTQAQAHDLVIKSLDKLKEVREFLGENIS
NFLSLAGNTYQLTRGIGKDIRALRRARANLQSVPHASASRPRVTEPISAESGEQVERVNEPSILEMSRGVKLTDVAPVSFFLVLDVVYLV

--------------------------------------------------------------
>96164_96164_4_UBE2L3-APOL1_UBE2L3_chr22_21965332_ENST00000342192_APOL1_chr22_36657642_ENST00000426053_length(transcript)=3015nt_BP=508nt
AAACGCTGAGGCCCAGTCTGTGCGGTTCACTTGCGTTCCTCCACGCGCCCCCCAGCACAGTGGGAAGCACACAGTAGGTGCTCCGCTCTG
CTCCTGTGCCCCGCCCCGCGGCCCCTCCCCCGCTCCAGGAAGTGCGGGGGCTCCAGCCGCCCGGCCGGCCGCGATGCATTCTGGGGAAGG
AGCAGCACCAAATCCAAGATGGCGGCCAGCAGGAGGCTGATGAAGGAGCTTGAAGAAATCCGCAAATGTGGGATGAAAAACTTCCGTAAC
ATCCAGGTTGATGAAGCTAATTTATTGACTTGGCAAGGGCTTATTGTTCCTGACAACCCTCCATATGATAAGGGAGCCTTCAGAATCGAA
ATCAACTTTCCAGCAGAGTACCCATTCAAACCACCGAAGATCACATTTAAAACAAAGATCTATCACCCAAACATCGACGAAAAGGGGCAG
GTCTGTCTGCCAGTAATTAGTGCCGAAAACTGGAAGCCAGCAACCAAAACCGACCAAGAGAGCAGTATCTTTATTGAGGATGCCATTAAG
TATTTCAAGGAAAAAGTGAGCACACAGAATCTGCTACTCCTGCTGACTGATAATGAGGCCTGGAACGGATTCGTGGCTGCTGCTGAACTG
CCCAGGAATGAGGCAGATGAGCTCCGTAAAGCTCTGGACAACCTTGCAAGACAAATGATCATGAAAGACAAAAACTGGCACGATAAAGGC
CAGCAGTACAGAAACTGGTTTCTGAAAGAGTTTCCTCGGTTGAAAAGTGAGCTTGAGGATAACATAAGAAGGCTCCGTGCCCTTGCAGAT
GGGGTTCAGAAGGTCCACAAAGGCACCACCATCGCCAATGTGGTGTCTGGCTCTCTCAGCATTTCCTCTGGCATCCTGACCCTCGTCGGC
ATGGGTCTGGCACCCTTCACAGAGGGAGGCAGCCTTGTACTCTTGGAACCTGGGATGGAGTTGGGAATCACAGCCGCTTTGACCGGGATT
ACCAGCAGTACCATGGACTACGGAAAGAAGTGGTGGACACAAGCCCAAGCCCACGACCTGGTCATCAAAAGCCTTGACAAATTGAAGGAG
GTGAGGGAGTTTTTGGGTGAGAACATATCCAACTTTCTTTCCTTAGCTGGCAATACTTACCAACTCACACGAGGCATTGGGAAGGACATC
CGTGCCCTCAGACGAGCCAGAGCCAATCTTCAGTCAGTACCGCATGCCTCAGCCTCACGCCCCCGGGTCACTGAGCCAATCTCAGCTGAA
AGCGGTGAACAGGTGGAGAGGGTTAATGAACCCAGCATCCTGGAAATGAGCAGAGGAGTCAAGCTCACGGATGTGGCCCCTGTAAGCTTC
TTTCTTGTGCTGGATGTAGTCTACCTCGTGTACGAATCAAAGCACTTACATGAGGGGGCAAAGTCAGAGACAGCTGAGGAGCTGAAGAAG
GTGGCTCAGGAGCTGGAGGAGAAGCTAAACATTCTCAACAATAATTATAAGATTCTGCAGGCGGACCAAGAACTGTGACCACAGGGCAGG
GCAGCCACCAGGAGAGATATGCCTGGCAGGGGCCAGGACAAAATGCAAACTTTTTTTTTTTTCTGAGACAGAGTCTTGCTCTGTCGCCAA
GTTGGAGTGCAATGGTGCGATCTCAGCTCACTGCAAGCTCTGCCTCCCGTGTTCAAGCGATTCTCCTGCCTTGGCCTCCCAAGTAGCTGG
GACTACAGGCGCCTACCACCATGCCCAGCTAATTTTTGTATTTTTAATAGAGATGGGGTTTCACCATGTTGGCCAGGATGGTCTCGATCT
CCTGACCTCTTGATCTGCCCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCATCGCTTTTGACCCAAATGCAAACATTTTA
TTAGGGGGATAAAGAGGGTGAGGTAAAGTTTATGGAACTGAGTGTTAGGGACTTTGGCATTTCCATAGCTGAGCACAGCAGGGGAGGGGT
TAATGCAGATGGCAGTGCAGCAAGGAGAAGGCAGGAACATTGGAGCCTGCAATAAGGGAAAAATGGGAACTGGAGAGTGTGGGGAATGGG
AAGAAGCAGTTTACTTTAGACTAAAGAATATATTGGGGGGCCGGGTGTAGTGGCTCATGCCTGTAATCCGAGCACTTTGGGAGGCCAAGG
CGGGCGGATCACGAGGTCAGGAGATCGAGACCATCCTGGCTAACACAGTGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCCGGGC
ATGGTGGCGGGCGCCTGTAGTTCCAGCTAACTGGGCGGCTGAGGCAGGAGAATGGCGTGAACCTGGGAGGTGGAGCTTGCAGTGAGCCGA
GATATCGCCACTGCACTCCAGCCTGGGTGACAGAGCGAGACTCCATCTCAAAAAAAAAAAAAAAAAGAATATATTGACGGAAGAATAGAG
AGGAGGCTTGAAGGAACCAGCAATGAGAAGGCCAGGAAAAGAAAGAGCTGAAAATGGAGAAAGCCCAAGAGTTAGAACAGTTGGATACAG
GAGAAGAAACAGCGGCTCCACTACAGACCCAGCCCCAGGTTCAATGTCCTCCGAAGAATGAAGTCTTTCCCTGGTGATGGTCCCCTGCCC
TGTCTTTCCAGCATCCACTCTCCCTTGTCCTCCTGGGGGCATATCTCAGTCAGGCAGCGGCTTCCTGATGATGGTCATTGGGGTGGTTGT
CATGTGATGGGTCCCCTCCAGGTTACTAAAGGGTGCATGTCCCCTGCTTGAACACTGAAGGGCAGGTGGTGGGCCATGGCCATGGTCCCC
AGCTGAGGAGCAGGTGTCCCTGAGAACCCAAACTTCCCAGAGAGTATGTGAGAACCAACCAATGAAAACAGTCCCATCGCTCTTACCCGG
TAAGTAAACAGTCAGAAAATTAGCATGAAAGCAGTTTAGCATTGGGAGGAAGCTCAGATCTCTAGAGCTGTCTTGTCGCCGCCCAGGATT

>96164_96164_4_UBE2L3-APOL1_UBE2L3_chr22_21965332_ENST00000342192_APOL1_chr22_36657642_ENST00000426053_length(amino acids)=495AA_BP=146
MRSSTRPPAQWEAHSRCSALLLCPAPRPLPRSRKCGGSSRPAGRDAFWGRSSTKSKMAASRRLMKELEEIRKCGMKNFRNIQVDEANLLT
WQGLIVPDNPPYDKGAFRIEINFPAEYPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQESSIFIEDAIKYFKEKVSTQN
LLLLLTDNEAWNGFVAAAELPRNEADELRKALDNLARQMIMKDKNWHDKGQQYRNWFLKEFPRLKSELEDNIRRLRALADGVQKVHKGTT
IANVVSGSLSISSGILTLVGMGLAPFTEGGSLVLLEPGMELGITAALTGITSSTMDYGKKWWTQAQAHDLVIKSLDKLKEVREFLGENIS
NFLSLAGNTYQLTRGIGKDIRALRRARANLQSVPHASASRPRVTEPISAESGEQVERVNEPSILEMSRGVKLTDVAPVSFFLVLDVVYLV

--------------------------------------------------------------
>96164_96164_5_UBE2L3-APOL1_UBE2L3_chr22_21965332_ENST00000458578_APOL1_chr22_36657642_ENST00000319136_length(transcript)=2985nt_BP=487nt
AGTATGCAGGTCGCTGCAGGGACCCGAGGCGACACGCGCCTGCAGGAGGTGGCACTCCTGCCGCAGCTCTTCGATCTGCTTGTCCTTGGC
CAGCGGCGCGCTCGCCTGCTCCGACAGGTCCCGAGCGCGCTGGCGGGCAAAGACTTGGCACAGCTCCAGGCCGGCGCAACTCTCGCCGGG
TATAGGCGCGCTCACGGCCCGGAGGAGCTTGAAGAAATCCGCAAATGTGGGATGAAAAACTTCCGTAACATCCAGGTTGATGAAGCTAAT
TTATTGACTTGGCAAGGGCTTATTGTTCCTGACAACCCTCCATATGATAAGGGAGCCTTCAGAATCGAAATCAACTTTCCAGCAGAGTAC
CCATTCAAACCACCGAAGATCACATTTAAAACAAAGATCTATCACCCAAACATCGACGAAAAGGGGCAGGTCTGTCTGCCAGTAATTAGT
GCCGAAAACTGGAAGCCAGCAACCAAAACCGACCAAGAGAGCAGTATCTTTATTGAGGATGCCATTAAGTATTTCAAGGAAAAAGTGAGC
ACACAGAATCTGCTACTCCTGCTGACTGATAATGAGGCCTGGAACGGATTCGTGGCTGCTGCTGAACTGCCCAGGAATGAGGCAGATGAG
CTCCGTAAAGCTCTGGACAACCTTGCAAGACAAATGATCATGAAAGACAAAAACTGGCACGATAAAGGCCAGCAGTACAGAAACTGGTTT
CTGAAAGAGTTTCCTCGGTTGAAAAGTGAGCTTGAGGATAACATAAGAAGGCTCCGTGCCCTTGCAGATGGGGTTCAGAAGGTCCACAAA
GGCACCACCATCGCCAATGTGGTGTCTGGCTCTCTCAGCATTTCCTCTGGCATCCTGACCCTCGTCGGCATGGGTCTGGCACCCTTCACA
GAGGGAGGCAGCCTTGTACTCTTGGAACCTGGGATGGAGTTGGGAATCACAGCCGCTTTGACCGGGATTACCAGCAGTACCATGGACTAC
GGAAAGAAGTGGTGGACACAAGCCCAAGCCCACGACCTGGTCATCAAAAGCCTTGACAAATTGAAGGAGGTGAGGGAGTTTTTGGGTGAG
AACATATCCAACTTTCTTTCCTTAGCTGGCAATACTTACCAACTCACACGAGGCATTGGGAAGGACATCCGTGCCCTCAGACGAGCCAGA
GCCAATCTTCAGTCAGTACCGCATGCCTCAGCCTCACGCCCCCGGGTCACTGAGCCAATCTCAGCTGAAAGCGGTGAACAGGTGGAGAGG
GTTAATGAACCCAGCATCCTGGAAATGAGCAGAGGAGTCAAGCTCACGGATGTGGCCCCTGTAAGCTTCTTTCTTGTGCTGGATGTAGTC
TACCTCGTGTACGAATCAAAGCACTTACATGAGGGGGCAAAGTCAGAGACAGCTGAGGAGCTGAAGAAGGTGGCTCAGGAGCTGGAGGAG
AAGCTAAACATTCTCAACAATAATTATAAGATTCTGCAGGCGGACCAAGAACTGTGACCACAGGGCAGGGCAGCCACCAGGAGAGATATG
CCTGGCAGGGGCCAGGACAAAATGCAAACTTTTTTTTTTTTCTGAGACAGAGTCTTGCTCTGTCGCCAAGTTGGAGTGCAATGGTGCGAT
CTCAGCTCACTGCAAGCTCTGCCTCCCGTGTTCAAGCGATTCTCCTGCCTTGGCCTCCCAAGTAGCTGGGACTACAGGCGCCTACCACCA
TGCCCAGCTAATTTTTGTATTTTTAATAGAGATGGGGTTTCACCATGTTGGCCAGGATGGTCTCGATCTCCTGACCTCTTGATCTGCCCA
CCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCATCGCTTTTGACCCAAATGCAAACATTTTATTAGGGGGATAAAGAGGGTGA
GGTAAAGTTTATGGAACTGAGTGTTAGGGACTTTGGCATTTCCATAGCTGAGCACAGCAGGGGAGGGGTTAATGCAGATGGCAGTGCAGC
AAGGAGAAGGCAGGAACATTGGAGCCTGCAATAAGGGAAAAATGGGAACTGGAGAGTGTGGGGAATGGGAAGAAGCAGTTTACTTTAGAC
TAAAGAATATATTGGGGGGCCGGGTGTAGTGGCTCATGCCTGTAATCCGAGCACTTTGGGAGGCCAAGGCGGGCGGATCACGAGGTCAGG
AGATCGAGACCATCCTGGCTAACACAGTGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCCGGGCATGGTGGCGGGCGCCTGTAGT
TCCAGCTAACTGGGCGGCTGAGGCAGGAGAATGGCGTGAACCTGGGAGGTGGAGCTTGCAGTGAGCCGAGATATCGCCACTGCACTCCAG
CCTGGGTGACAGAGCGAGACTCCATCTCAAAAAAAAAAAAAAAAAGAATATATTGACGGAAGAATAGAGAGGAGGCTTGAAGGAACCAGC
AATGAGAAGGCCAGGAAAAGAAAGAGCTGAAAATGGAGAAAGCCCAAGAGTTAGAACAGTTGGATACAGGAGAAGAAACAGCGGCTCCAC
TACAGACCCAGCCCCAGGTTCAATGTCCTCCGAAGAATGAAGTCTTTCCCTGGTGATGGTCCCCTGCCCTGTCTTTCCAGCATCCACTCT
CCCTTGTCCTCCTGGGGGCATATCTCAGTCAGGCAGCGGCTTCCTGATGATGGTCATTGGGGTGGTTGTCATGTGATGGGTCCCCTCCAG
GTTACTAAAGGGTGCATGTCCCCTGCTTGAACACTGAAGGGCAGGTGGTGGGCCATGGCCATGGTCCCCAGCTGAGGAGCAGGTGTCCCT
GAGAACCCAAACTTCCCAGAGAGTATGTGAGAACCAACCAATGAAAACAGTCCCATCGCTCTTACCCGGTAAGTAAACAGTCAGAAAATT
AGCATGAAAGCAGTTTAGCATTGGGAGGAAGCTCAGATCTCTAGAGCTGTCTTGTCGCCGCCCAGGATTGACCTGTGTGTAAGTCCCAAT

>96164_96164_5_UBE2L3-APOL1_UBE2L3_chr22_21965332_ENST00000458578_APOL1_chr22_36657642_ENST00000319136_length(amino acids)=497AA_BP=148
MQVAAGTRGDTRLQEVALLPQLFDLLVLGQRRARLLRQVPSALAGKDLAQLQAGATLAGYRRAHGPEELEEIRKCGMKNFRNIQVDEANL
LTWQGLIVPDNPPYDKGAFRIEINFPAEYPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQESSIFIEDAIKYFKEKVST
QNLLLLLTDNEAWNGFVAAAELPRNEADELRKALDNLARQMIMKDKNWHDKGQQYRNWFLKEFPRLKSELEDNIRRLRALADGVQKVHKG
TTIANVVSGSLSISSGILTLVGMGLAPFTEGGSLVLLEPGMELGITAALTGITSSTMDYGKKWWTQAQAHDLVIKSLDKLKEVREFLGEN
ISNFLSLAGNTYQLTRGIGKDIRALRRARANLQSVPHASASRPRVTEPISAESGEQVERVNEPSILEMSRGVKLTDVAPVSFFLVLDVVY

--------------------------------------------------------------
>96164_96164_6_UBE2L3-APOL1_UBE2L3_chr22_21965332_ENST00000458578_APOL1_chr22_36657642_ENST00000397278_length(transcript)=2989nt_BP=487nt
AGTATGCAGGTCGCTGCAGGGACCCGAGGCGACACGCGCCTGCAGGAGGTGGCACTCCTGCCGCAGCTCTTCGATCTGCTTGTCCTTGGC
CAGCGGCGCGCTCGCCTGCTCCGACAGGTCCCGAGCGCGCTGGCGGGCAAAGACTTGGCACAGCTCCAGGCCGGCGCAACTCTCGCCGGG
TATAGGCGCGCTCACGGCCCGGAGGAGCTTGAAGAAATCCGCAAATGTGGGATGAAAAACTTCCGTAACATCCAGGTTGATGAAGCTAAT
TTATTGACTTGGCAAGGGCTTATTGTTCCTGACAACCCTCCATATGATAAGGGAGCCTTCAGAATCGAAATCAACTTTCCAGCAGAGTAC
CCATTCAAACCACCGAAGATCACATTTAAAACAAAGATCTATCACCCAAACATCGACGAAAAGGGGCAGGTCTGTCTGCCAGTAATTAGT
GCCGAAAACTGGAAGCCAGCAACCAAAACCGACCAAGAGAGCAGTATCTTTATTGAGGATGCCATTAAGTATTTCAAGGAAAAAGTGAGC
ACACAGAATCTGCTACTCCTGCTGACTGATAATGAGGCCTGGAACGGATTCGTGGCTGCTGCTGAACTGCCCAGGAATGAGGCAGATGAG
CTCCGTAAAGCTCTGGACAACCTTGCAAGACAAATGATCATGAAAGACAAAAACTGGCACGATAAAGGCCAGCAGTACAGAAACTGGTTT
CTGAAAGAGTTTCCTCGGTTGAAAAGTGAGCTTGAGGATAACATAAGAAGGCTCCGTGCCCTTGCAGATGGGGTTCAGAAGGTCCACAAA
GGCACCACCATCGCCAATGTGGTGTCTGGCTCTCTCAGCATTTCCTCTGGCATCCTGACCCTCGTCGGCATGGGTCTGGCACCCTTCACA
GAGGGAGGCAGCCTTGTACTCTTGGAACCTGGGATGGAGTTGGGAATCACAGCCGCTTTGACCGGGATTACCAGCAGTACCATGGACTAC
GGAAAGAAGTGGTGGACACAAGCCCAAGCCCACGACCTGGTCATCAAAAGCCTTGACAAATTGAAGGAGGTGAGGGAGTTTTTGGGTGAG
AACATATCCAACTTTCTTTCCTTAGCTGGCAATACTTACCAACTCACACGAGGCATTGGGAAGGACATCCGTGCCCTCAGACGAGCCAGA
GCCAATCTTCAGTCAGTACCGCATGCCTCAGCCTCACGCCCCCGGGTCACTGAGCCAATCTCAGCTGAAAGCGGTGAACAGGTGGAGAGG
GTTAATGAACCCAGCATCCTGGAAATGAGCAGAGGAGTCAAGCTCACGGATGTGGCCCCTGTAAGCTTCTTTCTTGTGCTGGATGTAGTC
TACCTCGTGTACGAATCAAAGCACTTACATGAGGGGGCAAAGTCAGAGACAGCTGAGGAGCTGAAGAAGGTGGCTCAGGAGCTGGAGGAG
AAGCTAAACATTCTCAACAATAATTATAAGATTCTGCAGGCGGACCAAGAACTGTGACCACAGGGCAGGGCAGCCACCAGGAGAGATATG
CCTGGCAGGGGCCAGGACAAAATGCAAACTTTTTTTTTTTTCTGAGACAGAGTCTTGCTCTGTCGCCAAGTTGGAGTGCAATGGTGCGAT
CTCAGCTCACTGCAAGCTCTGCCTCCCGTGTTCAAGCGATTCTCCTGCCTTGGCCTCCCAAGTAGCTGGGACTACAGGCGCCTACCACCA
TGCCCAGCTAATTTTTGTATTTTTAATAGAGATGGGGTTTCACCATGTTGGCCAGGATGGTCTCGATCTCCTGACCTCTTGATCTGCCCA
CCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCATCGCTTTTGACCCAAATGCAAACATTTTATTAGGGGGATAAAGAGGGTGA
GGTAAAGTTTATGGAACTGAGTGTTAGGGACTTTGGCATTTCCATAGCTGAGCACAGCAGGGGAGGGGTTAATGCAGATGGCAGTGCAGC
AAGGAGAAGGCAGGAACATTGGAGCCTGCAATAAGGGAAAAATGGGAACTGGAGAGTGTGGGGAATGGGAAGAAGCAGTTTACTTTAGAC
TAAAGAATATATTGGGGGGCCGGGTGTAGTGGCTCATGCCTGTAATCCGAGCACTTTGGGAGGCCAAGGCGGGCGGATCACGAGGTCAGG
AGATCGAGACCATCCTGGCTAACACAGTGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCCGGGCATGGTGGCGGGCGCCTGTAGT
TCCAGCTAACTGGGCGGCTGAGGCAGGAGAATGGCGTGAACCTGGGAGGTGGAGCTTGCAGTGAGCCGAGATATCGCCACTGCACTCCAG
CCTGGGTGACAGAGCGAGACTCCATCTCAAAAAAAAAAAAAAAAAGAATATATTGACGGAAGAATAGAGAGGAGGCTTGAAGGAACCAGC
AATGAGAAGGCCAGGAAAAGAAAGAGCTGAAAATGGAGAAAGCCCAAGAGTTAGAACAGTTGGATACAGGAGAAGAAACAGCGGCTCCAC
TACAGACCCAGCCCCAGGTTCAATGTCCTCCGAAGAATGAAGTCTTTCCCTGGTGATGGTCCCCTGCCCTGTCTTTCCAGCATCCACTCT
CCCTTGTCCTCCTGGGGGCATATCTCAGTCAGGCAGCGGCTTCCTGATGATGGTCATTGGGGTGGTTGTCATGTGATGGGTCCCCTCCAG
GTTACTAAAGGGTGCATGTCCCCTGCTTGAACACTGAAGGGCAGGTGGTGGGCCATGGCCATGGTCCCCAGCTGAGGAGCAGGTGTCCCT
GAGAACCCAAACTTCCCAGAGAGTATGTGAGAACCAACCAATGAAAACAGTCCCATCGCTCTTACCCGGTAAGTAAACAGTCAGAAAATT
AGCATGAAAGCAGTTTAGCATTGGGAGGAAGCTCAGATCTCTAGAGCTGTCTTGTCGCCGCCCAGGATTGACCTGTGTGTAAGTCCCAAT

>96164_96164_6_UBE2L3-APOL1_UBE2L3_chr22_21965332_ENST00000458578_APOL1_chr22_36657642_ENST00000397278_length(amino acids)=497AA_BP=148
MQVAAGTRGDTRLQEVALLPQLFDLLVLGQRRARLLRQVPSALAGKDLAQLQAGATLAGYRRAHGPEELEEIRKCGMKNFRNIQVDEANL
LTWQGLIVPDNPPYDKGAFRIEINFPAEYPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQESSIFIEDAIKYFKEKVST
QNLLLLLTDNEAWNGFVAAAELPRNEADELRKALDNLARQMIMKDKNWHDKGQQYRNWFLKEFPRLKSELEDNIRRLRALADGVQKVHKG
TTIANVVSGSLSISSGILTLVGMGLAPFTEGGSLVLLEPGMELGITAALTGITSSTMDYGKKWWTQAQAHDLVIKSLDKLKEVREFLGEN
ISNFLSLAGNTYQLTRGIGKDIRALRRARANLQSVPHASASRPRVTEPISAESGEQVERVNEPSILEMSRGVKLTDVAPVSFFLVLDVVY

--------------------------------------------------------------
>96164_96164_7_UBE2L3-APOL1_UBE2L3_chr22_21965332_ENST00000458578_APOL1_chr22_36657642_ENST00000422706_length(transcript)=2994nt_BP=487nt
AGTATGCAGGTCGCTGCAGGGACCCGAGGCGACACGCGCCTGCAGGAGGTGGCACTCCTGCCGCAGCTCTTCGATCTGCTTGTCCTTGGC
CAGCGGCGCGCTCGCCTGCTCCGACAGGTCCCGAGCGCGCTGGCGGGCAAAGACTTGGCACAGCTCCAGGCCGGCGCAACTCTCGCCGGG
TATAGGCGCGCTCACGGCCCGGAGGAGCTTGAAGAAATCCGCAAATGTGGGATGAAAAACTTCCGTAACATCCAGGTTGATGAAGCTAAT
TTATTGACTTGGCAAGGGCTTATTGTTCCTGACAACCCTCCATATGATAAGGGAGCCTTCAGAATCGAAATCAACTTTCCAGCAGAGTAC
CCATTCAAACCACCGAAGATCACATTTAAAACAAAGATCTATCACCCAAACATCGACGAAAAGGGGCAGGTCTGTCTGCCAGTAATTAGT
GCCGAAAACTGGAAGCCAGCAACCAAAACCGACCAAGAGAGCAGTATCTTTATTGAGGATGCCATTAAGTATTTCAAGGAAAAAGTGAGC
ACACAGAATCTGCTACTCCTGCTGACTGATAATGAGGCCTGGAACGGATTCGTGGCTGCTGCTGAACTGCCCAGGAATGAGGCAGATGAG
CTCCGTAAAGCTCTGGACAACCTTGCAAGACAAATGATCATGAAAGACAAAAACTGGCACGATAAAGGCCAGCAGTACAGAAACTGGTTT
CTGAAAGAGTTTCCTCGGTTGAAAAGTGAGCTTGAGGATAACATAAGAAGGCTCCGTGCCCTTGCAGATGGGGTTCAGAAGGTCCACAAA
GGCACCACCATCGCCAATGTGGTGTCTGGCTCTCTCAGCATTTCCTCTGGCATCCTGACCCTCGTCGGCATGGGTCTGGCACCCTTCACA
GAGGGAGGCAGCCTTGTACTCTTGGAACCTGGGATGGAGTTGGGAATCACAGCCGCTTTGACCGGGATTACCAGCAGTACCATGGACTAC
GGAAAGAAGTGGTGGACACAAGCCCAAGCCCACGACCTGGTCATCAAAAGCCTTGACAAATTGAAGGAGGTGAGGGAGTTTTTGGGTGAG
AACATATCCAACTTTCTTTCCTTAGCTGGCAATACTTACCAACTCACACGAGGCATTGGGAAGGACATCCGTGCCCTCAGACGAGCCAGA
GCCAATCTTCAGTCAGTACCGCATGCCTCAGCCTCACGCCCCCGGGTCACTGAGCCAATCTCAGCTGAAAGCGGTGAACAGGTGGAGAGG
GTTAATGAACCCAGCATCCTGGAAATGAGCAGAGGAGTCAAGCTCACGGATGTGGCCCCTGTAAGCTTCTTTCTTGTGCTGGATGTAGTC
TACCTCGTGTACGAATCAAAGCACTTACATGAGGGGGCAAAGTCAGAGACAGCTGAGGAGCTGAAGAAGGTGGCTCAGGAGCTGGAGGAG
AAGCTAAACATTCTCAACAATAATTATAAGATTCTGCAGGCGGACCAAGAACTGTGACCACAGGGCAGGGCAGCCACCAGGAGAGATATG
CCTGGCAGGGGCCAGGACAAAATGCAAACTTTTTTTTTTTTCTGAGACAGAGTCTTGCTCTGTCGCCAAGTTGGAGTGCAATGGTGCGAT
CTCAGCTCACTGCAAGCTCTGCCTCCCGTGTTCAAGCGATTCTCCTGCCTTGGCCTCCCAAGTAGCTGGGACTACAGGCGCCTACCACCA
TGCCCAGCTAATTTTTGTATTTTTAATAGAGATGGGGTTTCACCATGTTGGCCAGGATGGTCTCGATCTCCTGACCTCTTGATCTGCCCA
CCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCATCGCTTTTGACCCAAATGCAAACATTTTATTAGGGGGATAAAGAGGGTGA
GGTAAAGTTTATGGAACTGAGTGTTAGGGACTTTGGCATTTCCATAGCTGAGCACAGCAGGGGAGGGGTTAATGCAGATGGCAGTGCAGC
AAGGAGAAGGCAGGAACATTGGAGCCTGCAATAAGGGAAAAATGGGAACTGGAGAGTGTGGGGAATGGGAAGAAGCAGTTTACTTTAGAC
TAAAGAATATATTGGGGGGCCGGGTGTAGTGGCTCATGCCTGTAATCCGAGCACTTTGGGAGGCCAAGGCGGGCGGATCACGAGGTCAGG
AGATCGAGACCATCCTGGCTAACACAGTGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCCGGGCATGGTGGCGGGCGCCTGTAGT
TCCAGCTAACTGGGCGGCTGAGGCAGGAGAATGGCGTGAACCTGGGAGGTGGAGCTTGCAGTGAGCCGAGATATCGCCACTGCACTCCAG
CCTGGGTGACAGAGCGAGACTCCATCTCAAAAAAAAAAAAAAAAAGAATATATTGACGGAAGAATAGAGAGGAGGCTTGAAGGAACCAGC
AATGAGAAGGCCAGGAAAAGAAAGAGCTGAAAATGGAGAAAGCCCAAGAGTTAGAACAGTTGGATACAGGAGAAGAAACAGCGGCTCCAC
TACAGACCCAGCCCCAGGTTCAATGTCCTCCGAAGAATGAAGTCTTTCCCTGGTGATGGTCCCCTGCCCTGTCTTTCCAGCATCCACTCT
CCCTTGTCCTCCTGGGGGCATATCTCAGTCAGGCAGCGGCTTCCTGATGATGGTCATTGGGGTGGTTGTCATGTGATGGGTCCCCTCCAG
GTTACTAAAGGGTGCATGTCCCCTGCTTGAACACTGAAGGGCAGGTGGTGGGCCATGGCCATGGTCCCCAGCTGAGGAGCAGGTGTCCCT
GAGAACCCAAACTTCCCAGAGAGTATGTGAGAACCAACCAATGAAAACAGTCCCATCGCTCTTACCCGGTAAGTAAACAGTCAGAAAATT
AGCATGAAAGCAGTTTAGCATTGGGAGGAAGCTCAGATCTCTAGAGCTGTCTTGTCGCCGCCCAGGATTGACCTGTGTGTAAGTCCCAAT

>96164_96164_7_UBE2L3-APOL1_UBE2L3_chr22_21965332_ENST00000458578_APOL1_chr22_36657642_ENST00000422706_length(amino acids)=497AA_BP=148
MQVAAGTRGDTRLQEVALLPQLFDLLVLGQRRARLLRQVPSALAGKDLAQLQAGATLAGYRRAHGPEELEEIRKCGMKNFRNIQVDEANL
LTWQGLIVPDNPPYDKGAFRIEINFPAEYPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQESSIFIEDAIKYFKEKVST
QNLLLLLTDNEAWNGFVAAAELPRNEADELRKALDNLARQMIMKDKNWHDKGQQYRNWFLKEFPRLKSELEDNIRRLRALADGVQKVHKG
TTIANVVSGSLSISSGILTLVGMGLAPFTEGGSLVLLEPGMELGITAALTGITSSTMDYGKKWWTQAQAHDLVIKSLDKLKEVREFLGEN
ISNFLSLAGNTYQLTRGIGKDIRALRRARANLQSVPHASASRPRVTEPISAESGEQVERVNEPSILEMSRGVKLTDVAPVSFFLVLDVVY

--------------------------------------------------------------
>96164_96164_8_UBE2L3-APOL1_UBE2L3_chr22_21965332_ENST00000458578_APOL1_chr22_36657642_ENST00000426053_length(transcript)=2994nt_BP=487nt
AGTATGCAGGTCGCTGCAGGGACCCGAGGCGACACGCGCCTGCAGGAGGTGGCACTCCTGCCGCAGCTCTTCGATCTGCTTGTCCTTGGC
CAGCGGCGCGCTCGCCTGCTCCGACAGGTCCCGAGCGCGCTGGCGGGCAAAGACTTGGCACAGCTCCAGGCCGGCGCAACTCTCGCCGGG
TATAGGCGCGCTCACGGCCCGGAGGAGCTTGAAGAAATCCGCAAATGTGGGATGAAAAACTTCCGTAACATCCAGGTTGATGAAGCTAAT
TTATTGACTTGGCAAGGGCTTATTGTTCCTGACAACCCTCCATATGATAAGGGAGCCTTCAGAATCGAAATCAACTTTCCAGCAGAGTAC
CCATTCAAACCACCGAAGATCACATTTAAAACAAAGATCTATCACCCAAACATCGACGAAAAGGGGCAGGTCTGTCTGCCAGTAATTAGT
GCCGAAAACTGGAAGCCAGCAACCAAAACCGACCAAGAGAGCAGTATCTTTATTGAGGATGCCATTAAGTATTTCAAGGAAAAAGTGAGC
ACACAGAATCTGCTACTCCTGCTGACTGATAATGAGGCCTGGAACGGATTCGTGGCTGCTGCTGAACTGCCCAGGAATGAGGCAGATGAG
CTCCGTAAAGCTCTGGACAACCTTGCAAGACAAATGATCATGAAAGACAAAAACTGGCACGATAAAGGCCAGCAGTACAGAAACTGGTTT
CTGAAAGAGTTTCCTCGGTTGAAAAGTGAGCTTGAGGATAACATAAGAAGGCTCCGTGCCCTTGCAGATGGGGTTCAGAAGGTCCACAAA
GGCACCACCATCGCCAATGTGGTGTCTGGCTCTCTCAGCATTTCCTCTGGCATCCTGACCCTCGTCGGCATGGGTCTGGCACCCTTCACA
GAGGGAGGCAGCCTTGTACTCTTGGAACCTGGGATGGAGTTGGGAATCACAGCCGCTTTGACCGGGATTACCAGCAGTACCATGGACTAC
GGAAAGAAGTGGTGGACACAAGCCCAAGCCCACGACCTGGTCATCAAAAGCCTTGACAAATTGAAGGAGGTGAGGGAGTTTTTGGGTGAG
AACATATCCAACTTTCTTTCCTTAGCTGGCAATACTTACCAACTCACACGAGGCATTGGGAAGGACATCCGTGCCCTCAGACGAGCCAGA
GCCAATCTTCAGTCAGTACCGCATGCCTCAGCCTCACGCCCCCGGGTCACTGAGCCAATCTCAGCTGAAAGCGGTGAACAGGTGGAGAGG
GTTAATGAACCCAGCATCCTGGAAATGAGCAGAGGAGTCAAGCTCACGGATGTGGCCCCTGTAAGCTTCTTTCTTGTGCTGGATGTAGTC
TACCTCGTGTACGAATCAAAGCACTTACATGAGGGGGCAAAGTCAGAGACAGCTGAGGAGCTGAAGAAGGTGGCTCAGGAGCTGGAGGAG
AAGCTAAACATTCTCAACAATAATTATAAGATTCTGCAGGCGGACCAAGAACTGTGACCACAGGGCAGGGCAGCCACCAGGAGAGATATG
CCTGGCAGGGGCCAGGACAAAATGCAAACTTTTTTTTTTTTCTGAGACAGAGTCTTGCTCTGTCGCCAAGTTGGAGTGCAATGGTGCGAT
CTCAGCTCACTGCAAGCTCTGCCTCCCGTGTTCAAGCGATTCTCCTGCCTTGGCCTCCCAAGTAGCTGGGACTACAGGCGCCTACCACCA
TGCCCAGCTAATTTTTGTATTTTTAATAGAGATGGGGTTTCACCATGTTGGCCAGGATGGTCTCGATCTCCTGACCTCTTGATCTGCCCA
CCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCATCGCTTTTGACCCAAATGCAAACATTTTATTAGGGGGATAAAGAGGGTGA
GGTAAAGTTTATGGAACTGAGTGTTAGGGACTTTGGCATTTCCATAGCTGAGCACAGCAGGGGAGGGGTTAATGCAGATGGCAGTGCAGC
AAGGAGAAGGCAGGAACATTGGAGCCTGCAATAAGGGAAAAATGGGAACTGGAGAGTGTGGGGAATGGGAAGAAGCAGTTTACTTTAGAC
TAAAGAATATATTGGGGGGCCGGGTGTAGTGGCTCATGCCTGTAATCCGAGCACTTTGGGAGGCCAAGGCGGGCGGATCACGAGGTCAGG
AGATCGAGACCATCCTGGCTAACACAGTGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCCGGGCATGGTGGCGGGCGCCTGTAGT
TCCAGCTAACTGGGCGGCTGAGGCAGGAGAATGGCGTGAACCTGGGAGGTGGAGCTTGCAGTGAGCCGAGATATCGCCACTGCACTCCAG
CCTGGGTGACAGAGCGAGACTCCATCTCAAAAAAAAAAAAAAAAAGAATATATTGACGGAAGAATAGAGAGGAGGCTTGAAGGAACCAGC
AATGAGAAGGCCAGGAAAAGAAAGAGCTGAAAATGGAGAAAGCCCAAGAGTTAGAACAGTTGGATACAGGAGAAGAAACAGCGGCTCCAC
TACAGACCCAGCCCCAGGTTCAATGTCCTCCGAAGAATGAAGTCTTTCCCTGGTGATGGTCCCCTGCCCTGTCTTTCCAGCATCCACTCT
CCCTTGTCCTCCTGGGGGCATATCTCAGTCAGGCAGCGGCTTCCTGATGATGGTCATTGGGGTGGTTGTCATGTGATGGGTCCCCTCCAG
GTTACTAAAGGGTGCATGTCCCCTGCTTGAACACTGAAGGGCAGGTGGTGGGCCATGGCCATGGTCCCCAGCTGAGGAGCAGGTGTCCCT
GAGAACCCAAACTTCCCAGAGAGTATGTGAGAACCAACCAATGAAAACAGTCCCATCGCTCTTACCCGGTAAGTAAACAGTCAGAAAATT
AGCATGAAAGCAGTTTAGCATTGGGAGGAAGCTCAGATCTCTAGAGCTGTCTTGTCGCCGCCCAGGATTGACCTGTGTGTAAGTCCCAAT

>96164_96164_8_UBE2L3-APOL1_UBE2L3_chr22_21965332_ENST00000458578_APOL1_chr22_36657642_ENST00000426053_length(amino acids)=497AA_BP=148
MQVAAGTRGDTRLQEVALLPQLFDLLVLGQRRARLLRQVPSALAGKDLAQLQAGATLAGYRRAHGPEELEEIRKCGMKNFRNIQVDEANL
LTWQGLIVPDNPPYDKGAFRIEINFPAEYPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQESSIFIEDAIKYFKEKVST
QNLLLLLTDNEAWNGFVAAAELPRNEADELRKALDNLARQMIMKDKNWHDKGQQYRNWFLKEFPRLKSELEDNIRRLRALADGVQKVHKG
TTIANVVSGSLSISSGILTLVGMGLAPFTEGGSLVLLEPGMELGITAALTGITSSTMDYGKKWWTQAQAHDLVIKSLDKLKEVREFLGEN
ISNFLSLAGNTYQLTRGIGKDIRALRRARANLQSVPHASASRPRVTEPISAESGEQVERVNEPSILEMSRGVKLTDVAPVSFFLVLDVVY

--------------------------------------------------------------
>96164_96164_9_UBE2L3-APOL1_UBE2L3_chr22_21965332_ENST00000545681_APOL1_chr22_36657642_ENST00000319136_length(transcript)=2720nt_BP=222nt
AATCCAAGATGGCGGCCAGCAGGAGGCTGATGAAGGACAACCCTCCATATGATAAGGGAGCCTTCAGAATCGAAATCAACTTTCCAGCAG
AGTACCCATTCAAACCACCGAAGATCACATTTAAAACAAAGATCTATCACCCAAACATCGACGAAAAGGGGCAGGTCTGTCTGCCAGTAA
TTAGTGCCGAAAACTGGAAGCCAGCAACCAAAACCGACCAAGAGAGCAGTATCTTTATTGAGGATGCCATTAAGTATTTCAAGGAAAAAG
TGAGCACACAGAATCTGCTACTCCTGCTGACTGATAATGAGGCCTGGAACGGATTCGTGGCTGCTGCTGAACTGCCCAGGAATGAGGCAG
ATGAGCTCCGTAAAGCTCTGGACAACCTTGCAAGACAAATGATCATGAAAGACAAAAACTGGCACGATAAAGGCCAGCAGTACAGAAACT
GGTTTCTGAAAGAGTTTCCTCGGTTGAAAAGTGAGCTTGAGGATAACATAAGAAGGCTCCGTGCCCTTGCAGATGGGGTTCAGAAGGTCC
ACAAAGGCACCACCATCGCCAATGTGGTGTCTGGCTCTCTCAGCATTTCCTCTGGCATCCTGACCCTCGTCGGCATGGGTCTGGCACCCT
TCACAGAGGGAGGCAGCCTTGTACTCTTGGAACCTGGGATGGAGTTGGGAATCACAGCCGCTTTGACCGGGATTACCAGCAGTACCATGG
ACTACGGAAAGAAGTGGTGGACACAAGCCCAAGCCCACGACCTGGTCATCAAAAGCCTTGACAAATTGAAGGAGGTGAGGGAGTTTTTGG
GTGAGAACATATCCAACTTTCTTTCCTTAGCTGGCAATACTTACCAACTCACACGAGGCATTGGGAAGGACATCCGTGCCCTCAGACGAG
CCAGAGCCAATCTTCAGTCAGTACCGCATGCCTCAGCCTCACGCCCCCGGGTCACTGAGCCAATCTCAGCTGAAAGCGGTGAACAGGTGG
AGAGGGTTAATGAACCCAGCATCCTGGAAATGAGCAGAGGAGTCAAGCTCACGGATGTGGCCCCTGTAAGCTTCTTTCTTGTGCTGGATG
TAGTCTACCTCGTGTACGAATCAAAGCACTTACATGAGGGGGCAAAGTCAGAGACAGCTGAGGAGCTGAAGAAGGTGGCTCAGGAGCTGG
AGGAGAAGCTAAACATTCTCAACAATAATTATAAGATTCTGCAGGCGGACCAAGAACTGTGACCACAGGGCAGGGCAGCCACCAGGAGAG
ATATGCCTGGCAGGGGCCAGGACAAAATGCAAACTTTTTTTTTTTTCTGAGACAGAGTCTTGCTCTGTCGCCAAGTTGGAGTGCAATGGT
GCGATCTCAGCTCACTGCAAGCTCTGCCTCCCGTGTTCAAGCGATTCTCCTGCCTTGGCCTCCCAAGTAGCTGGGACTACAGGCGCCTAC
CACCATGCCCAGCTAATTTTTGTATTTTTAATAGAGATGGGGTTTCACCATGTTGGCCAGGATGGTCTCGATCTCCTGACCTCTTGATCT
GCCCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCATCGCTTTTGACCCAAATGCAAACATTTTATTAGGGGGATAAAGAG
GGTGAGGTAAAGTTTATGGAACTGAGTGTTAGGGACTTTGGCATTTCCATAGCTGAGCACAGCAGGGGAGGGGTTAATGCAGATGGCAGT
GCAGCAAGGAGAAGGCAGGAACATTGGAGCCTGCAATAAGGGAAAAATGGGAACTGGAGAGTGTGGGGAATGGGAAGAAGCAGTTTACTT
TAGACTAAAGAATATATTGGGGGGCCGGGTGTAGTGGCTCATGCCTGTAATCCGAGCACTTTGGGAGGCCAAGGCGGGCGGATCACGAGG
TCAGGAGATCGAGACCATCCTGGCTAACACAGTGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCCGGGCATGGTGGCGGGCGCCT
GTAGTTCCAGCTAACTGGGCGGCTGAGGCAGGAGAATGGCGTGAACCTGGGAGGTGGAGCTTGCAGTGAGCCGAGATATCGCCACTGCAC
TCCAGCCTGGGTGACAGAGCGAGACTCCATCTCAAAAAAAAAAAAAAAAAGAATATATTGACGGAAGAATAGAGAGGAGGCTTGAAGGAA
CCAGCAATGAGAAGGCCAGGAAAAGAAAGAGCTGAAAATGGAGAAAGCCCAAGAGTTAGAACAGTTGGATACAGGAGAAGAAACAGCGGC
TCCACTACAGACCCAGCCCCAGGTTCAATGTCCTCCGAAGAATGAAGTCTTTCCCTGGTGATGGTCCCCTGCCCTGTCTTTCCAGCATCC
ACTCTCCCTTGTCCTCCTGGGGGCATATCTCAGTCAGGCAGCGGCTTCCTGATGATGGTCATTGGGGTGGTTGTCATGTGATGGGTCCCC
TCCAGGTTACTAAAGGGTGCATGTCCCCTGCTTGAACACTGAAGGGCAGGTGGTGGGCCATGGCCATGGTCCCCAGCTGAGGAGCAGGTG
TCCCTGAGAACCCAAACTTCCCAGAGAGTATGTGAGAACCAACCAATGAAAACAGTCCCATCGCTCTTACCCGGTAAGTAAACAGTCAGA
AAATTAGCATGAAAGCAGTTTAGCATTGGGAGGAAGCTCAGATCTCTAGAGCTGTCTTGTCGCCGCCCAGGATTGACCTGTGTGTAAGTC

>96164_96164_9_UBE2L3-APOL1_UBE2L3_chr22_21965332_ENST00000545681_APOL1_chr22_36657642_ENST00000319136_length(amino acids)=407AA_BP=58
MAASRRLMKDNPPYDKGAFRIEINFPAEYPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQESSIFIEDAIKYFKEKVST
QNLLLLLTDNEAWNGFVAAAELPRNEADELRKALDNLARQMIMKDKNWHDKGQQYRNWFLKEFPRLKSELEDNIRRLRALADGVQKVHKG
TTIANVVSGSLSISSGILTLVGMGLAPFTEGGSLVLLEPGMELGITAALTGITSSTMDYGKKWWTQAQAHDLVIKSLDKLKEVREFLGEN
ISNFLSLAGNTYQLTRGIGKDIRALRRARANLQSVPHASASRPRVTEPISAESGEQVERVNEPSILEMSRGVKLTDVAPVSFFLVLDVVY

--------------------------------------------------------------
>96164_96164_10_UBE2L3-APOL1_UBE2L3_chr22_21965332_ENST00000545681_APOL1_chr22_36657642_ENST00000397278_length(transcript)=2724nt_BP=222nt
AATCCAAGATGGCGGCCAGCAGGAGGCTGATGAAGGACAACCCTCCATATGATAAGGGAGCCTTCAGAATCGAAATCAACTTTCCAGCAG
AGTACCCATTCAAACCACCGAAGATCACATTTAAAACAAAGATCTATCACCCAAACATCGACGAAAAGGGGCAGGTCTGTCTGCCAGTAA
TTAGTGCCGAAAACTGGAAGCCAGCAACCAAAACCGACCAAGAGAGCAGTATCTTTATTGAGGATGCCATTAAGTATTTCAAGGAAAAAG
TGAGCACACAGAATCTGCTACTCCTGCTGACTGATAATGAGGCCTGGAACGGATTCGTGGCTGCTGCTGAACTGCCCAGGAATGAGGCAG
ATGAGCTCCGTAAAGCTCTGGACAACCTTGCAAGACAAATGATCATGAAAGACAAAAACTGGCACGATAAAGGCCAGCAGTACAGAAACT
GGTTTCTGAAAGAGTTTCCTCGGTTGAAAAGTGAGCTTGAGGATAACATAAGAAGGCTCCGTGCCCTTGCAGATGGGGTTCAGAAGGTCC
ACAAAGGCACCACCATCGCCAATGTGGTGTCTGGCTCTCTCAGCATTTCCTCTGGCATCCTGACCCTCGTCGGCATGGGTCTGGCACCCT
TCACAGAGGGAGGCAGCCTTGTACTCTTGGAACCTGGGATGGAGTTGGGAATCACAGCCGCTTTGACCGGGATTACCAGCAGTACCATGG
ACTACGGAAAGAAGTGGTGGACACAAGCCCAAGCCCACGACCTGGTCATCAAAAGCCTTGACAAATTGAAGGAGGTGAGGGAGTTTTTGG
GTGAGAACATATCCAACTTTCTTTCCTTAGCTGGCAATACTTACCAACTCACACGAGGCATTGGGAAGGACATCCGTGCCCTCAGACGAG
CCAGAGCCAATCTTCAGTCAGTACCGCATGCCTCAGCCTCACGCCCCCGGGTCACTGAGCCAATCTCAGCTGAAAGCGGTGAACAGGTGG
AGAGGGTTAATGAACCCAGCATCCTGGAAATGAGCAGAGGAGTCAAGCTCACGGATGTGGCCCCTGTAAGCTTCTTTCTTGTGCTGGATG
TAGTCTACCTCGTGTACGAATCAAAGCACTTACATGAGGGGGCAAAGTCAGAGACAGCTGAGGAGCTGAAGAAGGTGGCTCAGGAGCTGG
AGGAGAAGCTAAACATTCTCAACAATAATTATAAGATTCTGCAGGCGGACCAAGAACTGTGACCACAGGGCAGGGCAGCCACCAGGAGAG
ATATGCCTGGCAGGGGCCAGGACAAAATGCAAACTTTTTTTTTTTTCTGAGACAGAGTCTTGCTCTGTCGCCAAGTTGGAGTGCAATGGT
GCGATCTCAGCTCACTGCAAGCTCTGCCTCCCGTGTTCAAGCGATTCTCCTGCCTTGGCCTCCCAAGTAGCTGGGACTACAGGCGCCTAC
CACCATGCCCAGCTAATTTTTGTATTTTTAATAGAGATGGGGTTTCACCATGTTGGCCAGGATGGTCTCGATCTCCTGACCTCTTGATCT
GCCCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCATCGCTTTTGACCCAAATGCAAACATTTTATTAGGGGGATAAAGAG
GGTGAGGTAAAGTTTATGGAACTGAGTGTTAGGGACTTTGGCATTTCCATAGCTGAGCACAGCAGGGGAGGGGTTAATGCAGATGGCAGT
GCAGCAAGGAGAAGGCAGGAACATTGGAGCCTGCAATAAGGGAAAAATGGGAACTGGAGAGTGTGGGGAATGGGAAGAAGCAGTTTACTT
TAGACTAAAGAATATATTGGGGGGCCGGGTGTAGTGGCTCATGCCTGTAATCCGAGCACTTTGGGAGGCCAAGGCGGGCGGATCACGAGG
TCAGGAGATCGAGACCATCCTGGCTAACACAGTGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCCGGGCATGGTGGCGGGCGCCT
GTAGTTCCAGCTAACTGGGCGGCTGAGGCAGGAGAATGGCGTGAACCTGGGAGGTGGAGCTTGCAGTGAGCCGAGATATCGCCACTGCAC
TCCAGCCTGGGTGACAGAGCGAGACTCCATCTCAAAAAAAAAAAAAAAAAGAATATATTGACGGAAGAATAGAGAGGAGGCTTGAAGGAA
CCAGCAATGAGAAGGCCAGGAAAAGAAAGAGCTGAAAATGGAGAAAGCCCAAGAGTTAGAACAGTTGGATACAGGAGAAGAAACAGCGGC
TCCACTACAGACCCAGCCCCAGGTTCAATGTCCTCCGAAGAATGAAGTCTTTCCCTGGTGATGGTCCCCTGCCCTGTCTTTCCAGCATCC
ACTCTCCCTTGTCCTCCTGGGGGCATATCTCAGTCAGGCAGCGGCTTCCTGATGATGGTCATTGGGGTGGTTGTCATGTGATGGGTCCCC
TCCAGGTTACTAAAGGGTGCATGTCCCCTGCTTGAACACTGAAGGGCAGGTGGTGGGCCATGGCCATGGTCCCCAGCTGAGGAGCAGGTG
TCCCTGAGAACCCAAACTTCCCAGAGAGTATGTGAGAACCAACCAATGAAAACAGTCCCATCGCTCTTACCCGGTAAGTAAACAGTCAGA
AAATTAGCATGAAAGCAGTTTAGCATTGGGAGGAAGCTCAGATCTCTAGAGCTGTCTTGTCGCCGCCCAGGATTGACCTGTGTGTAAGTC

>96164_96164_10_UBE2L3-APOL1_UBE2L3_chr22_21965332_ENST00000545681_APOL1_chr22_36657642_ENST00000397278_length(amino acids)=407AA_BP=58
MAASRRLMKDNPPYDKGAFRIEINFPAEYPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQESSIFIEDAIKYFKEKVST
QNLLLLLTDNEAWNGFVAAAELPRNEADELRKALDNLARQMIMKDKNWHDKGQQYRNWFLKEFPRLKSELEDNIRRLRALADGVQKVHKG
TTIANVVSGSLSISSGILTLVGMGLAPFTEGGSLVLLEPGMELGITAALTGITSSTMDYGKKWWTQAQAHDLVIKSLDKLKEVREFLGEN
ISNFLSLAGNTYQLTRGIGKDIRALRRARANLQSVPHASASRPRVTEPISAESGEQVERVNEPSILEMSRGVKLTDVAPVSFFLVLDVVY

--------------------------------------------------------------
>96164_96164_11_UBE2L3-APOL1_UBE2L3_chr22_21965332_ENST00000545681_APOL1_chr22_36657642_ENST00000422706_length(transcript)=2729nt_BP=222nt
AATCCAAGATGGCGGCCAGCAGGAGGCTGATGAAGGACAACCCTCCATATGATAAGGGAGCCTTCAGAATCGAAATCAACTTTCCAGCAG
AGTACCCATTCAAACCACCGAAGATCACATTTAAAACAAAGATCTATCACCCAAACATCGACGAAAAGGGGCAGGTCTGTCTGCCAGTAA
TTAGTGCCGAAAACTGGAAGCCAGCAACCAAAACCGACCAAGAGAGCAGTATCTTTATTGAGGATGCCATTAAGTATTTCAAGGAAAAAG
TGAGCACACAGAATCTGCTACTCCTGCTGACTGATAATGAGGCCTGGAACGGATTCGTGGCTGCTGCTGAACTGCCCAGGAATGAGGCAG
ATGAGCTCCGTAAAGCTCTGGACAACCTTGCAAGACAAATGATCATGAAAGACAAAAACTGGCACGATAAAGGCCAGCAGTACAGAAACT
GGTTTCTGAAAGAGTTTCCTCGGTTGAAAAGTGAGCTTGAGGATAACATAAGAAGGCTCCGTGCCCTTGCAGATGGGGTTCAGAAGGTCC
ACAAAGGCACCACCATCGCCAATGTGGTGTCTGGCTCTCTCAGCATTTCCTCTGGCATCCTGACCCTCGTCGGCATGGGTCTGGCACCCT
TCACAGAGGGAGGCAGCCTTGTACTCTTGGAACCTGGGATGGAGTTGGGAATCACAGCCGCTTTGACCGGGATTACCAGCAGTACCATGG
ACTACGGAAAGAAGTGGTGGACACAAGCCCAAGCCCACGACCTGGTCATCAAAAGCCTTGACAAATTGAAGGAGGTGAGGGAGTTTTTGG
GTGAGAACATATCCAACTTTCTTTCCTTAGCTGGCAATACTTACCAACTCACACGAGGCATTGGGAAGGACATCCGTGCCCTCAGACGAG
CCAGAGCCAATCTTCAGTCAGTACCGCATGCCTCAGCCTCACGCCCCCGGGTCACTGAGCCAATCTCAGCTGAAAGCGGTGAACAGGTGG
AGAGGGTTAATGAACCCAGCATCCTGGAAATGAGCAGAGGAGTCAAGCTCACGGATGTGGCCCCTGTAAGCTTCTTTCTTGTGCTGGATG
TAGTCTACCTCGTGTACGAATCAAAGCACTTACATGAGGGGGCAAAGTCAGAGACAGCTGAGGAGCTGAAGAAGGTGGCTCAGGAGCTGG
AGGAGAAGCTAAACATTCTCAACAATAATTATAAGATTCTGCAGGCGGACCAAGAACTGTGACCACAGGGCAGGGCAGCCACCAGGAGAG
ATATGCCTGGCAGGGGCCAGGACAAAATGCAAACTTTTTTTTTTTTCTGAGACAGAGTCTTGCTCTGTCGCCAAGTTGGAGTGCAATGGT
GCGATCTCAGCTCACTGCAAGCTCTGCCTCCCGTGTTCAAGCGATTCTCCTGCCTTGGCCTCCCAAGTAGCTGGGACTACAGGCGCCTAC
CACCATGCCCAGCTAATTTTTGTATTTTTAATAGAGATGGGGTTTCACCATGTTGGCCAGGATGGTCTCGATCTCCTGACCTCTTGATCT
GCCCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCATCGCTTTTGACCCAAATGCAAACATTTTATTAGGGGGATAAAGAG
GGTGAGGTAAAGTTTATGGAACTGAGTGTTAGGGACTTTGGCATTTCCATAGCTGAGCACAGCAGGGGAGGGGTTAATGCAGATGGCAGT
GCAGCAAGGAGAAGGCAGGAACATTGGAGCCTGCAATAAGGGAAAAATGGGAACTGGAGAGTGTGGGGAATGGGAAGAAGCAGTTTACTT
TAGACTAAAGAATATATTGGGGGGCCGGGTGTAGTGGCTCATGCCTGTAATCCGAGCACTTTGGGAGGCCAAGGCGGGCGGATCACGAGG
TCAGGAGATCGAGACCATCCTGGCTAACACAGTGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCCGGGCATGGTGGCGGGCGCCT
GTAGTTCCAGCTAACTGGGCGGCTGAGGCAGGAGAATGGCGTGAACCTGGGAGGTGGAGCTTGCAGTGAGCCGAGATATCGCCACTGCAC
TCCAGCCTGGGTGACAGAGCGAGACTCCATCTCAAAAAAAAAAAAAAAAAGAATATATTGACGGAAGAATAGAGAGGAGGCTTGAAGGAA
CCAGCAATGAGAAGGCCAGGAAAAGAAAGAGCTGAAAATGGAGAAAGCCCAAGAGTTAGAACAGTTGGATACAGGAGAAGAAACAGCGGC
TCCACTACAGACCCAGCCCCAGGTTCAATGTCCTCCGAAGAATGAAGTCTTTCCCTGGTGATGGTCCCCTGCCCTGTCTTTCCAGCATCC
ACTCTCCCTTGTCCTCCTGGGGGCATATCTCAGTCAGGCAGCGGCTTCCTGATGATGGTCATTGGGGTGGTTGTCATGTGATGGGTCCCC
TCCAGGTTACTAAAGGGTGCATGTCCCCTGCTTGAACACTGAAGGGCAGGTGGTGGGCCATGGCCATGGTCCCCAGCTGAGGAGCAGGTG
TCCCTGAGAACCCAAACTTCCCAGAGAGTATGTGAGAACCAACCAATGAAAACAGTCCCATCGCTCTTACCCGGTAAGTAAACAGTCAGA
AAATTAGCATGAAAGCAGTTTAGCATTGGGAGGAAGCTCAGATCTCTAGAGCTGTCTTGTCGCCGCCCAGGATTGACCTGTGTGTAAGTC

>96164_96164_11_UBE2L3-APOL1_UBE2L3_chr22_21965332_ENST00000545681_APOL1_chr22_36657642_ENST00000422706_length(amino acids)=407AA_BP=58
MAASRRLMKDNPPYDKGAFRIEINFPAEYPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQESSIFIEDAIKYFKEKVST
QNLLLLLTDNEAWNGFVAAAELPRNEADELRKALDNLARQMIMKDKNWHDKGQQYRNWFLKEFPRLKSELEDNIRRLRALADGVQKVHKG
TTIANVVSGSLSISSGILTLVGMGLAPFTEGGSLVLLEPGMELGITAALTGITSSTMDYGKKWWTQAQAHDLVIKSLDKLKEVREFLGEN
ISNFLSLAGNTYQLTRGIGKDIRALRRARANLQSVPHASASRPRVTEPISAESGEQVERVNEPSILEMSRGVKLTDVAPVSFFLVLDVVY

--------------------------------------------------------------
>96164_96164_12_UBE2L3-APOL1_UBE2L3_chr22_21965332_ENST00000545681_APOL1_chr22_36657642_ENST00000426053_length(transcript)=2729nt_BP=222nt
AATCCAAGATGGCGGCCAGCAGGAGGCTGATGAAGGACAACCCTCCATATGATAAGGGAGCCTTCAGAATCGAAATCAACTTTCCAGCAG
AGTACCCATTCAAACCACCGAAGATCACATTTAAAACAAAGATCTATCACCCAAACATCGACGAAAAGGGGCAGGTCTGTCTGCCAGTAA
TTAGTGCCGAAAACTGGAAGCCAGCAACCAAAACCGACCAAGAGAGCAGTATCTTTATTGAGGATGCCATTAAGTATTTCAAGGAAAAAG
TGAGCACACAGAATCTGCTACTCCTGCTGACTGATAATGAGGCCTGGAACGGATTCGTGGCTGCTGCTGAACTGCCCAGGAATGAGGCAG
ATGAGCTCCGTAAAGCTCTGGACAACCTTGCAAGACAAATGATCATGAAAGACAAAAACTGGCACGATAAAGGCCAGCAGTACAGAAACT
GGTTTCTGAAAGAGTTTCCTCGGTTGAAAAGTGAGCTTGAGGATAACATAAGAAGGCTCCGTGCCCTTGCAGATGGGGTTCAGAAGGTCC
ACAAAGGCACCACCATCGCCAATGTGGTGTCTGGCTCTCTCAGCATTTCCTCTGGCATCCTGACCCTCGTCGGCATGGGTCTGGCACCCT
TCACAGAGGGAGGCAGCCTTGTACTCTTGGAACCTGGGATGGAGTTGGGAATCACAGCCGCTTTGACCGGGATTACCAGCAGTACCATGG
ACTACGGAAAGAAGTGGTGGACACAAGCCCAAGCCCACGACCTGGTCATCAAAAGCCTTGACAAATTGAAGGAGGTGAGGGAGTTTTTGG
GTGAGAACATATCCAACTTTCTTTCCTTAGCTGGCAATACTTACCAACTCACACGAGGCATTGGGAAGGACATCCGTGCCCTCAGACGAG
CCAGAGCCAATCTTCAGTCAGTACCGCATGCCTCAGCCTCACGCCCCCGGGTCACTGAGCCAATCTCAGCTGAAAGCGGTGAACAGGTGG
AGAGGGTTAATGAACCCAGCATCCTGGAAATGAGCAGAGGAGTCAAGCTCACGGATGTGGCCCCTGTAAGCTTCTTTCTTGTGCTGGATG
TAGTCTACCTCGTGTACGAATCAAAGCACTTACATGAGGGGGCAAAGTCAGAGACAGCTGAGGAGCTGAAGAAGGTGGCTCAGGAGCTGG
AGGAGAAGCTAAACATTCTCAACAATAATTATAAGATTCTGCAGGCGGACCAAGAACTGTGACCACAGGGCAGGGCAGCCACCAGGAGAG
ATATGCCTGGCAGGGGCCAGGACAAAATGCAAACTTTTTTTTTTTTCTGAGACAGAGTCTTGCTCTGTCGCCAAGTTGGAGTGCAATGGT
GCGATCTCAGCTCACTGCAAGCTCTGCCTCCCGTGTTCAAGCGATTCTCCTGCCTTGGCCTCCCAAGTAGCTGGGACTACAGGCGCCTAC
CACCATGCCCAGCTAATTTTTGTATTTTTAATAGAGATGGGGTTTCACCATGTTGGCCAGGATGGTCTCGATCTCCTGACCTCTTGATCT
GCCCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCATCGCTTTTGACCCAAATGCAAACATTTTATTAGGGGGATAAAGAG
GGTGAGGTAAAGTTTATGGAACTGAGTGTTAGGGACTTTGGCATTTCCATAGCTGAGCACAGCAGGGGAGGGGTTAATGCAGATGGCAGT
GCAGCAAGGAGAAGGCAGGAACATTGGAGCCTGCAATAAGGGAAAAATGGGAACTGGAGAGTGTGGGGAATGGGAAGAAGCAGTTTACTT
TAGACTAAAGAATATATTGGGGGGCCGGGTGTAGTGGCTCATGCCTGTAATCCGAGCACTTTGGGAGGCCAAGGCGGGCGGATCACGAGG
TCAGGAGATCGAGACCATCCTGGCTAACACAGTGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCCGGGCATGGTGGCGGGCGCCT
GTAGTTCCAGCTAACTGGGCGGCTGAGGCAGGAGAATGGCGTGAACCTGGGAGGTGGAGCTTGCAGTGAGCCGAGATATCGCCACTGCAC
TCCAGCCTGGGTGACAGAGCGAGACTCCATCTCAAAAAAAAAAAAAAAAAGAATATATTGACGGAAGAATAGAGAGGAGGCTTGAAGGAA
CCAGCAATGAGAAGGCCAGGAAAAGAAAGAGCTGAAAATGGAGAAAGCCCAAGAGTTAGAACAGTTGGATACAGGAGAAGAAACAGCGGC
TCCACTACAGACCCAGCCCCAGGTTCAATGTCCTCCGAAGAATGAAGTCTTTCCCTGGTGATGGTCCCCTGCCCTGTCTTTCCAGCATCC
ACTCTCCCTTGTCCTCCTGGGGGCATATCTCAGTCAGGCAGCGGCTTCCTGATGATGGTCATTGGGGTGGTTGTCATGTGATGGGTCCCC
TCCAGGTTACTAAAGGGTGCATGTCCCCTGCTTGAACACTGAAGGGCAGGTGGTGGGCCATGGCCATGGTCCCCAGCTGAGGAGCAGGTG
TCCCTGAGAACCCAAACTTCCCAGAGAGTATGTGAGAACCAACCAATGAAAACAGTCCCATCGCTCTTACCCGGTAAGTAAACAGTCAGA
AAATTAGCATGAAAGCAGTTTAGCATTGGGAGGAAGCTCAGATCTCTAGAGCTGTCTTGTCGCCGCCCAGGATTGACCTGTGTGTAAGTC

>96164_96164_12_UBE2L3-APOL1_UBE2L3_chr22_21965332_ENST00000545681_APOL1_chr22_36657642_ENST00000426053_length(amino acids)=407AA_BP=58
MAASRRLMKDNPPYDKGAFRIEINFPAEYPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQESSIFIEDAIKYFKEKVST
QNLLLLLTDNEAWNGFVAAAELPRNEADELRKALDNLARQMIMKDKNWHDKGQQYRNWFLKEFPRLKSELEDNIRRLRALADGVQKVHKG
TTIANVVSGSLSISSGILTLVGMGLAPFTEGGSLVLLEPGMELGITAALTGITSSTMDYGKKWWTQAQAHDLVIKSLDKLKEVREFLGEN
ISNFLSLAGNTYQLTRGIGKDIRALRRARANLQSVPHASASRPRVTEPISAESGEQVERVNEPSILEMSRGVKLTDVAPVSFFLVLDVVY

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Fusion Gene PPI Analysis for UBE2L3-APOL1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for UBE2L3-APOL1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for UBE2L3-APOL1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource