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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:UBE4B-PLEKHG5 (FusionGDB2 ID:96333)

Fusion Gene Summary for UBE4B-PLEKHG5

Fusion gene summary

Fusion gene information	Fusion gene name: UBE4B-PLEKHG5
	Fusion gene ID: 96333
		Hgene	Tgene
	Gene symbol	UBE4B	PLEKHG5
	Gene ID	10277	57449
	Gene name	ubiquitination factor E4B	pleckstrin homology and RhoGEF domain containing G5
	Synonyms	E4\|HDNB1\|UBOX3\|UFD2\|UFD2A	CMTRIC\|DSMA4\|GEF720\|Syx\|Tech
	Cytomap	1p36.22	1p36.31
	Type of gene	protein-coding	protein-coding
	Description	ubiquitin conjugation factor E4 BRING-type E3 ubiquitin transferase E4 BUFD2A-III/UBE4B-III splice isoformhomologous to yeast UFD2homozygously deleted in neuroblastoma-1ubiquitin-fusion degradation protein 2ubiquitination factor E4B (UFD2 homolog, y	pleckstrin homology domain-containing family G member 5NFkB activating proteinPH domain-containing family G member 5guanine nucleotide exchange factor 720novel PH domain-containing proteinpleckstrin homology domain containing, family G (with RhoGef d
	Modification date	20200313	20200320
	UniProtAcc	.	.
	Ensembl transtripts involved in fusion gene	ENST00000253251, ENST00000343090, ENST00000377153, ENST00000377157, ENST00000475795,	ENST00000340850, ENST00000377725, ENST00000377728, ENST00000377732, ENST00000377737, ENST00000377740, ENST00000400913, ENST00000400915, ENST00000535355, ENST00000537245, ENST00000544978, ENST00000377748,
Fusion gene scores	* DoF score	18 X 13 X 10=2340	4 X 3 X 4=48
	# samples	23	6
	** MAII score	log2(23/2340*10)=-3.34680276352639 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(6/48*10)=0.321928094887362 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0
Context	PubMed: UBE4B [Title/Abstract] AND PLEKHG5 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	UBE4B(10093752)-PLEKHG5(6556629), # samples:2
Anticipated loss of major functional domain due to fusion event.	UBE4B-PLEKHG5 seems lost the major protein functional domain in Hgene partner, which is a tumor suppressor due to the frame-shifted ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	UBE4B	GO:0008626	granzyme-mediated apoptotic signaling pathway	11802788
Hgene	UBE4B	GO:0009411	response to UV	11802788
Hgene	UBE4B	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	23509263

Fusion gene breakpoints across UBE4B (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across PLEKHG5 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	LUSC	TCGA-56-7730-01A	UBE4B	chr1	10093752	-	PLEKHG5	chr1	6556629	-
ChimerDB4	LUSC	TCGA-56-7730-01A	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
ChimerDB4	LUSC	TCGA-56-7730	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-

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Fusion Gene ORF analysis for UBE4B-PLEKHG5

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-5UTR	ENST00000253251	ENST00000340850	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
5CDS-5UTR	ENST00000253251	ENST00000377725	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
5CDS-5UTR	ENST00000253251	ENST00000377728	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
5CDS-5UTR	ENST00000253251	ENST00000377732	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
5CDS-5UTR	ENST00000253251	ENST00000377737	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
5CDS-5UTR	ENST00000253251	ENST00000377737	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
5CDS-5UTR	ENST00000253251	ENST00000377740	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
5CDS-5UTR	ENST00000253251	ENST00000400913	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
5CDS-5UTR	ENST00000253251	ENST00000400915	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
5CDS-5UTR	ENST00000253251	ENST00000535355	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
5CDS-5UTR	ENST00000253251	ENST00000537245	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
5CDS-5UTR	ENST00000253251	ENST00000537245	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
5CDS-5UTR	ENST00000253251	ENST00000544978	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
5CDS-5UTR	ENST00000253251	ENST00000544978	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
5CDS-5UTR	ENST00000343090	ENST00000340850	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
5CDS-5UTR	ENST00000343090	ENST00000377725	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
5CDS-5UTR	ENST00000343090	ENST00000377728	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
5CDS-5UTR	ENST00000343090	ENST00000377732	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
5CDS-5UTR	ENST00000343090	ENST00000377737	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
5CDS-5UTR	ENST00000343090	ENST00000377737	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
5CDS-5UTR	ENST00000343090	ENST00000377740	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
5CDS-5UTR	ENST00000343090	ENST00000400913	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
5CDS-5UTR	ENST00000343090	ENST00000400915	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
5CDS-5UTR	ENST00000343090	ENST00000535355	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
5CDS-5UTR	ENST00000343090	ENST00000537245	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
5CDS-5UTR	ENST00000343090	ENST00000537245	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
5CDS-5UTR	ENST00000343090	ENST00000544978	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
5CDS-5UTR	ENST00000343090	ENST00000544978	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
5CDS-5UTR	ENST00000377153	ENST00000340850	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
5CDS-5UTR	ENST00000377153	ENST00000377725	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
5CDS-5UTR	ENST00000377153	ENST00000377728	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
5CDS-5UTR	ENST00000377153	ENST00000377732	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
5CDS-5UTR	ENST00000377153	ENST00000377737	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
5CDS-5UTR	ENST00000377153	ENST00000377737	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
5CDS-5UTR	ENST00000377153	ENST00000377740	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
5CDS-5UTR	ENST00000377153	ENST00000400913	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
5CDS-5UTR	ENST00000377153	ENST00000400915	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
5CDS-5UTR	ENST00000377153	ENST00000535355	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
5CDS-5UTR	ENST00000377153	ENST00000537245	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
5CDS-5UTR	ENST00000377153	ENST00000537245	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
5CDS-5UTR	ENST00000377153	ENST00000544978	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
5CDS-5UTR	ENST00000377153	ENST00000544978	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
5CDS-intron	ENST00000253251	ENST00000340850	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
5CDS-intron	ENST00000253251	ENST00000377725	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
5CDS-intron	ENST00000253251	ENST00000377728	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
5CDS-intron	ENST00000253251	ENST00000400913	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
5CDS-intron	ENST00000253251	ENST00000535355	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
5CDS-intron	ENST00000343090	ENST00000340850	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
5CDS-intron	ENST00000343090	ENST00000377725	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
5CDS-intron	ENST00000343090	ENST00000377728	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
5CDS-intron	ENST00000343090	ENST00000400913	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
5CDS-intron	ENST00000343090	ENST00000535355	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
5CDS-intron	ENST00000377153	ENST00000340850	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
5CDS-intron	ENST00000377153	ENST00000377725	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
5CDS-intron	ENST00000377153	ENST00000377728	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
5CDS-intron	ENST00000377153	ENST00000400913	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
5CDS-intron	ENST00000377153	ENST00000535355	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
5UTR-3CDS	ENST00000377157	ENST00000377732	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
5UTR-3CDS	ENST00000377157	ENST00000377740	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
5UTR-3CDS	ENST00000377157	ENST00000377748	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
5UTR-3CDS	ENST00000377157	ENST00000377748	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
5UTR-3CDS	ENST00000377157	ENST00000400915	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
5UTR-5UTR	ENST00000377157	ENST00000340850	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
5UTR-5UTR	ENST00000377157	ENST00000377725	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
5UTR-5UTR	ENST00000377157	ENST00000377728	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
5UTR-5UTR	ENST00000377157	ENST00000377732	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
5UTR-5UTR	ENST00000377157	ENST00000377737	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
5UTR-5UTR	ENST00000377157	ENST00000377737	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
5UTR-5UTR	ENST00000377157	ENST00000377740	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
5UTR-5UTR	ENST00000377157	ENST00000400913	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
5UTR-5UTR	ENST00000377157	ENST00000400915	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
5UTR-5UTR	ENST00000377157	ENST00000535355	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
5UTR-5UTR	ENST00000377157	ENST00000537245	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
5UTR-5UTR	ENST00000377157	ENST00000537245	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
5UTR-5UTR	ENST00000377157	ENST00000544978	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
5UTR-5UTR	ENST00000377157	ENST00000544978	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
5UTR-intron	ENST00000377157	ENST00000340850	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
5UTR-intron	ENST00000377157	ENST00000377725	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
5UTR-intron	ENST00000377157	ENST00000377728	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
5UTR-intron	ENST00000377157	ENST00000400913	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
5UTR-intron	ENST00000377157	ENST00000535355	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
Frame-shift	ENST00000253251	ENST00000377748	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
Frame-shift	ENST00000343090	ENST00000377748	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
Frame-shift	ENST00000377153	ENST00000377748	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
In-frame	ENST00000253251	ENST00000377732	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
In-frame	ENST00000253251	ENST00000377740	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
In-frame	ENST00000253251	ENST00000377748	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
In-frame	ENST00000253251	ENST00000400915	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
In-frame	ENST00000343090	ENST00000377732	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
In-frame	ENST00000343090	ENST00000377740	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
In-frame	ENST00000343090	ENST00000377748	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
In-frame	ENST00000343090	ENST00000400915	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
In-frame	ENST00000377153	ENST00000377732	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
In-frame	ENST00000377153	ENST00000377740	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
In-frame	ENST00000377153	ENST00000377748	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
In-frame	ENST00000377153	ENST00000400915	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
intron-3CDS	ENST00000475795	ENST00000377732	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
intron-3CDS	ENST00000475795	ENST00000377740	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
intron-3CDS	ENST00000475795	ENST00000377748	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
intron-3CDS	ENST00000475795	ENST00000377748	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
intron-3CDS	ENST00000475795	ENST00000400915	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
intron-5UTR	ENST00000475795	ENST00000340850	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
intron-5UTR	ENST00000475795	ENST00000377725	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
intron-5UTR	ENST00000475795	ENST00000377728	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
intron-5UTR	ENST00000475795	ENST00000377732	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
intron-5UTR	ENST00000475795	ENST00000377737	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
intron-5UTR	ENST00000475795	ENST00000377737	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
intron-5UTR	ENST00000475795	ENST00000377740	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
intron-5UTR	ENST00000475795	ENST00000400913	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
intron-5UTR	ENST00000475795	ENST00000400915	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
intron-5UTR	ENST00000475795	ENST00000535355	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
intron-5UTR	ENST00000475795	ENST00000537245	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
intron-5UTR	ENST00000475795	ENST00000537245	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
intron-5UTR	ENST00000475795	ENST00000544978	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
intron-5UTR	ENST00000475795	ENST00000544978	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-
intron-intron	ENST00000475795	ENST00000340850	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
intron-intron	ENST00000475795	ENST00000377725	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
intron-intron	ENST00000475795	ENST00000377728	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
intron-intron	ENST00000475795	ENST00000400913	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-
intron-intron	ENST00000475795	ENST00000535355	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6556629	-

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000253251	UBE4B	chr1	10093752	+	ENST00000377748	PLEKHG5	chr1	6537718	-	5442	863	839	3970	1043
ENST00000253251	UBE4B	chr1	10093752	+	ENST00000377732	PLEKHG5	chr1	6537718	-	4412	863	839	3970	1043
ENST00000253251	UBE4B	chr1	10093752	+	ENST00000400915	PLEKHG5	chr1	6537718	-	4412	863	839	3970	1043
ENST00000253251	UBE4B	chr1	10093752	+	ENST00000377740	PLEKHG5	chr1	6537718	-	3719	863	839	3277	812
ENST00000343090	UBE4B	chr1	10093752	+	ENST00000377748	PLEKHG5	chr1	6537718	-	4678	99	75	3206	1043
ENST00000343090	UBE4B	chr1	10093752	+	ENST00000377732	PLEKHG5	chr1	6537718	-	3648	99	75	3206	1043
ENST00000343090	UBE4B	chr1	10093752	+	ENST00000400915	PLEKHG5	chr1	6537718	-	3648	99	75	3206	1043
ENST00000343090	UBE4B	chr1	10093752	+	ENST00000377740	PLEKHG5	chr1	6537718	-	2955	99	75	2513	812
ENST00000377153	UBE4B	chr1	10093752	+	ENST00000377748	PLEKHG5	chr1	6537718	-	5000	421	397	3528	1043
ENST00000377153	UBE4B	chr1	10093752	+	ENST00000377732	PLEKHG5	chr1	6537718	-	3970	421	397	3528	1043
ENST00000377153	UBE4B	chr1	10093752	+	ENST00000400915	PLEKHG5	chr1	6537718	-	3970	421	397	3528	1043
ENST00000377153	UBE4B	chr1	10093752	+	ENST00000377740	PLEKHG5	chr1	6537718	-	3277	421	397	2835	812

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000253251	ENST00000377748	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-	0.008805921	0.99119407
ENST00000253251	ENST00000377732	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-	0.010236774	0.98976326
ENST00000253251	ENST00000400915	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-	0.010236774	0.98976326
ENST00000253251	ENST00000377740	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-	0.01088927	0.98911077
ENST00000343090	ENST00000377748	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-	0.00490252	0.99509746
ENST00000343090	ENST00000377732	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-	0.006059791	0.99394023
ENST00000343090	ENST00000400915	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-	0.006059791	0.99394023
ENST00000343090	ENST00000377740	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-	0.014210951	0.985789
ENST00000377153	ENST00000377748	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-	0.007028442	0.9929716
ENST00000377153	ENST00000377732	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-	0.008702754	0.99129725
ENST00000377153	ENST00000400915	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-	0.008702754	0.99129725
ENST00000377153	ENST00000377740	UBE4B	chr1	10093752	+	PLEKHG5	chr1	6537718	-	0.015159591	0.98484045

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Fusion Genomic Features for UBE4B-PLEKHG5

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for UBE4B-PLEKHG5

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:10093752/chr1:6556629)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	.
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

PLEKHG5

chr1:10093752

chr1:6537718

ENST00000340850

38_43

1007.0

Compositional bias

Note=Poly-Glu

Tgene

PLEKHG5

chr1:10093752

chr1:6537718

ENST00000377725

38_43

1020.6666666666666

Compositional bias

Note=Poly-Glu

Tgene

PLEKHG5

chr1:10093752

chr1:6537718

ENST00000377728

38_43

1007.0

Compositional bias

Note=Poly-Glu

Tgene

PLEKHG5

chr1:10093752

chr1:6537718

ENST00000377732

38_43

1044.0

Compositional bias

Note=Poly-Glu

Tgene

PLEKHG5

chr1:10093752

chr1:6537718

ENST00000377737

38_43

1007.0

Compositional bias

Note=Poly-Glu

Tgene

PLEKHG5

chr1:10093752

chr1:6537718

ENST00000400913

38_43

1007.0

Compositional bias

Note=Poly-Glu

Tgene

PLEKHG5

chr1:10093752

chr1:6537718

ENST00000400915

38_43

1063.0

Compositional bias

Note=Poly-Glu

Tgene

PLEKHG5

chr1:10093752

chr1:6537718

ENST00000535355

38_43

1076.0

Compositional bias

Note=Poly-Glu

Tgene

PLEKHG5

chr1:10093752

chr1:6537718

ENST00000544978

38_43

931.0

Compositional bias

Note=Poly-Glu

Tgene

PLEKHG5

chr1:10093752

chr1:6537718

ENST00000340850

336_528

1007.0

Domain

Tgene

PLEKHG5

chr1:10093752

chr1:6537718

ENST00000340850

584_684

1007.0

Domain

Tgene

PLEKHG5

chr1:10093752

chr1:6537718

ENST00000377725

336_528

1020.6666666666666

Domain

Tgene

PLEKHG5

chr1:10093752

chr1:6537718

ENST00000377725

584_684

1020.6666666666666

Domain

Tgene

PLEKHG5

chr1:10093752

chr1:6537718

ENST00000377728

336_528

1007.0

Domain

Tgene

PLEKHG5

chr1:10093752

chr1:6537718

ENST00000377728

584_684

1007.0

Domain

Tgene

PLEKHG5

chr1:10093752

chr1:6537718

ENST00000377732

336_528

1044.0

Domain

Tgene

PLEKHG5

chr1:10093752

chr1:6537718

ENST00000377732

584_684

1044.0

Domain

Tgene

PLEKHG5

chr1:10093752

chr1:6537718

ENST00000377737

336_528

1007.0

Domain

Tgene

PLEKHG5

chr1:10093752

chr1:6537718

ENST00000377737

584_684

1007.0

Domain

Tgene

PLEKHG5

chr1:10093752

chr1:6537718

ENST00000377748

336_528

1084.0

Domain

Tgene

PLEKHG5

chr1:10093752

chr1:6537718

ENST00000377748

584_684

1084.0

Domain

Tgene

PLEKHG5

chr1:10093752

chr1:6537718

ENST00000400913

336_528

1007.0

Domain

Tgene

PLEKHG5

chr1:10093752

chr1:6537718

ENST00000400913

584_684

1007.0

Domain

Tgene

PLEKHG5

chr1:10093752

chr1:6537718

ENST00000400915

336_528

1063.0

Domain

Tgene

PLEKHG5

chr1:10093752

chr1:6537718

ENST00000400915

584_684

1063.0

Domain

Tgene

PLEKHG5

chr1:10093752

chr1:6537718

ENST00000535355

336_528

1076.0

Domain

Tgene

PLEKHG5

chr1:10093752

chr1:6537718

ENST00000535355

584_684

1076.0

Domain

Tgene

PLEKHG5

chr1:10093752

chr1:6537718

ENST00000537245

336_528

1086.0

Domain

Tgene

PLEKHG5

chr1:10093752

chr1:6537718

ENST00000537245

584_684

1086.0

Domain

Tgene

PLEKHG5

chr1:10093752

chr1:6537718

ENST00000544978

336_528

931.0

Domain

Tgene

PLEKHG5

chr1:10093752

chr1:6537718

ENST00000544978

584_684

931.0

Domain

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

UBE4B

chr1:10093752

chr1:6537718

ENST00000253251

1227_1300

1174.0

Domain

Note=U-box

Hgene

UBE4B

chr1:10093752

chr1:6537718

ENST00000343090

1227_1300

1303.0

Domain

Note=U-box

Hgene

UBE4B

chr1:10093752

chr1:6537718

ENST00000377157

1227_1300

1062.0

Domain

Note=U-box

Tgene

PLEKHG5

chr1:10093752

chr1:6537718

ENST00000377748

38_43

1084.0

Compositional bias

Note=Poly-Glu

Tgene

PLEKHG5

chr1:10093752

chr1:6537718

ENST00000537245

38_43

1086.0

Compositional bias

Note=Poly-Glu

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Fusion Gene Sequence for UBE4B-PLEKHG5

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>96333_96333_1_UBE4B-PLEKHG5_UBE4B_chr1_10093752_ENST00000253251_PLEKHG5_chr1_6537718_ENST00000377732_length(transcript)=4412nt_BP=863nt
GACGGGGTGGGACGGAGGCGGGGAGAGGACGCAGGCGAGAGGAACTCGGCGGCGCGGCGCCCGCGGCCTATTGGCTGCCACGTCCCGGCG
CCAGAAGCCCCGCCTCCCTGACGGGGGTCACGTGATCCCTTTCAAAGATGGCCGCCCTGTTGTTTTGATGAATAATACTTGGTGGGGCGA
GGGGGAAAGAGTAGGGGTGGAGGGGTAGGAGGATTTACTCTTCCAGCGAGAGCTACGCGCATCCCATCCTCCCCCTCCCCCCTACCCGGG
CTCCGGCGTGGAGGCGGGGCGTGGCCGGCCTGCTTTGGGAGGGGAGGGGCTTCCCTTACAGTGCTGGGCTCTGCCAGGACGGCTGTGGGG
TCGCCTTACCTCGGGGTATCCACTCTGCAGTCGACCAGTTCCCGCCAGGAGCAAAGGGTAGGAAGGAGAGCAGGATCTGCTGTAGGAACG
CAGCTACCGCGCCACTATCACGAAGAAACAGCAGGCTCGGGGCACGAGACGAACTGGAGACCGCGCTGCCTAGCTGGGTAACCTGGGAAG
CAGAGGGTAATAAGTGGCGCCTTAAGACAACCCTGTAGCAGCAGCAGTGGCGGCCAAAGGAGGCTGCTCAGGGAACAAGCGGCTGTAGTA
GTCTGTGGGGCGACTGGAGTGACCGAAGCCAAGGCAGTTTAGTGCCTCTCGTGTTCTTATTTTTTAACCTCTGACTATGCAATTCTGAAA
CCTCCCCCATTCGGGGGACCAGACAGCCTGATAGACACCTTCCACTCTCCTTCCTCCCGCCGTGGTCTCGAGAACAGAAGGATCTCTCCT
TAACGCCTTTCACCATTAAGAGGAAAGCGATGGAGGAGCTGAGCGCTGATGAGGTATGTCACCACGCCGACTGCCAGCAGCTGCACCGCC
GGGGGCCCCTCAACCTCTGCGAGGCCTGTGACAGCAAGTTCCACAGCACCATGCATTATGATGGGCATGTCCGCTTCGACCTTCCCCCAC
AAGGCTCTGTGCTGGCCCGGAACGTGTCCACCCGGTCATGCCCGCCGCGCACCAGCCCCGCAGTGGACTTGGAGGAGGAGGAGGAGGAGA
GCTCTGTGGATGGCAAAGGGGACCGGAAGAGCACAGGCCTGAAACTCTCCAAGAAGAAAGCAAGGAGGAGACACACGGATGACCCAAGCA
AGGAATGCTTCACTCTGAAATTTGACCTGAATGTGGACATTGAGACAGAGATCGTCCCAGCCATGAAGAAGAAGTCACTGGGGGAGGTGC
TGCTGCCTGTATTTGAAAGGAAGGGCATTGCGCTGGGCAAAGTGGACATCTACCTGGACCAGTCCAACACACCCCTGTCCCTCACCTTCG
AGGCCTACAGGTTCGGGGGACACTACCTTCGTGTCAAAGCCCCAGCCAAGCCTGGAGATGAGGGCAAGGTGGAGCAGGGCATGAAGGACT
CCAAGTCCCTGAGTTTGCCGATTCTGCGGCCAGCTGGGACCGGGCCCCCCGCCCTGGAGCGTGTGGACGCCCAGAGCCGCCGGGAGAGCC
TGGACATCTTGGCCCCTGGCCGCCGCCGCAAGAACATGTCGGAGTTCCTGGGGGAGGCGAGCATCCCCGGGCAGGAGCCCCCCACGCCCT
CCAGCTGCTCTCTGCCCAGCGGCAGCAGTGGCAGCACCAACACTGGCGACAGCTGGAAGAACCGGGCGGCCAGTCGCTTCAGCGGCTTTT
TCAGCTCCGGCCCCAGCACCAGCGCCTTTGGCCGGGAGGTAGACAAGATGGAGCAGCTGGAGGGCAAGCTGCACACCTACAGCCTCTTCG
GGCTGCCCAGGCTGCCCCGGGGGCTGCGCTTCGACCATGACTCCTGGGAGGAGGAGTACGATGAAGACGAGGATGAGGACAATGCCTGCC
TGAGGCTGGAGGACAGCTGGCGGGAGCTCATTGATGGGCATGAGAAGCTGACCCGGCGGCAGTGCCACCAGCAGGAGGCGGTGTGGGAGC
TGCTGCACACGGAGGCCTCCTACATCAGGAAACTGCGGGTGATCATCAACCTGTTCCTGTGCTGCCTCCTGAACCTGCAAGAGTCAGGGC
TGCTGTGTGAGGTGGAGGCGGAGCGCCTGTTCAGCAACATCCCGGAGATCGCGCAGCTGCACCGCAGGCTGTGGGCTAGCGTGATGGCGC
CGGTGCTGGAGAAGGCGCGGCGCACGCGAGCGCTGCTACAGCCCGGGGACTTCCTCAAAGGCTTCAAGATGTTCGGCTCGCTCTTCAAGC
CCTACATCCGCTACTGCATGGAGGAGGAGGGCTGCATGGAGTACATGCGCGGCCTGCTGCGCGACAACGACCTCTTCCGGGCCTACATCA
CGTGGGCGGAGAAGCACCCACAGTGCCAGAGGCTGAAGCTGAGCGACATGCTGGCCAAACCCCACCAGCGGCTCACCAAGTACCCGCTGC
TGCTCAAGTCGGTGCTGAGGAAGACCGAGGAGCCGCGCGCCAAGGAGGCCGTCGTCGCCATGATCGGCTCCGTGGAGCGCTTCATCCACC
ACGTGAACGCGTGCATGCGGCAGCGGCAGGAGCGGCAGCGGCTGGCGGCCGTGGTGAGCCGCATCGACGCCTACGAGGTGGTGGAAAGCA
GCAGCGACGAAGTGGACAAGCTCCTGAAGGAATTTCTGCACCTGGACTTGACAGCGCCCATCCCTGGCGCCTCCCCGGAGGAGACGCGGC
AGCTGCTGCTGGAGGGGAGCCTGAGGATGAAGGAGGGGAAGGACAGCAAGATGGATGTGTACTGCTTCCTCTTCACGGATCTGCTGTTGG
TGACCAAAGCAGTGAAGAAGGCAGAGAGGACCAGGGTCATCAGGCCACCCCTGCTCGTGGACAAGATTGTGTGCCGGGAGCTACGGGACC
CTGGGTCCTTCCTCCTTATCTACCTGAATGAGTTTCACAGTGCTGTAGGGGCCTACACGTTCCAGGCCAGTGGCCAGGCCTTGTGCCGTG
GCTGGGTGGACACCATTTACAATGCCCAGAACCAGCTGCAACAGCTGCGTGCACAGGAGCCCCCAGGCAGTCAGCAGCCCCTGCAGAGCC
TGGAAGAGGAGGAGGATGAGCAGGAGGAGGAAGAGGAGGAGGAGGAGGAGGAGGAGGAAGGCGAGGACAGTGGCACTTCAGCTGCCAGCT
CCCCTACCATCATGCGGAAAAGCAGCGGCAGCCCCGACTCTCAGCACTGTGCCTCAGATGGCTCCACGGAGACCCTGGCCATGGTTGTGG
TAGAGCCTGGGGACACGCTGTCCTCCCCCGAGTTCGACAGCGGTCCTTTCAGCTCCCAGTCTGATGAGACCTCTCTCAGCACCACTGCCT
CATCTGCCACGCCCACCAGTGAGCTGCTGCCCCTGGGTCCGGTGGACGGCCGCTCCTGCTCCATGGACTCTGCCTACGGCACCCTCTCCC
CAACCTCCTTACAAGACTTTGTGGCCCCAGGCCCAATGGCAGAGCTAGTGCCTCGGGCCCCAGAGTCCCCACGAGTTCCTTCCCCTCCAC
CCTCGCCCCGTCTCCGCCGCCGCACCCCTGTCCAGCTGTTGAGCTGCCCGCCCCACCTGCTCAAGTCTAAGTCCGAGGCCAGCCTCCTCC
AGCTGCTGGCAGGGGCTGGCACCCATGGGACACCCTCTGCCCCCAGCCGCAGCCTGTCAGAGCTCTGCCTGGCTGTTCCAGCCCCAGGTA
TTAGGACTCAGGGCTCCCCTCAGGAAGCTGGGCCCAGCTGGGATTGCCGAGGGGCCCCTAGCCCTGGCAGCGGTCCTGGGCTAGTCGGCT
GCCTGGCCGGGGAACCTGCAGGCTCCCACAGGAAGAGGTGTGGAGACCTGCCCTCGGGGGCCTCTCCCAGGGTCCAGCCTGAGCCCCCAC
CAGGGGTCTCTGCCCAGCACAGGAAGCTGACCCTGGCCCAGCTCTACCGAATCAGGACCACCCTGCTGCTTAACTCCACGCTCACTGCCT
CGGAGGTCTGAGCAGAGGGAGGCCCCCAAGAGTGCCATTGACCAAGAGACAGCAGACAGCCTGCCTCCTGGGGCGTGCCGGCACCTGCTT
CAGCTACTGCCTCCTGTATGCATGAGCCGGATGCTGGGCAGGATCCCTGCCTACGCCCGGGCCCGATTTGCGCTTTGCCGGACTGGATGG
AGTGGAGGAGGCCCAGGCCACAGTACCACCCCACCTGCCCAGGCAGCCCCTCGTCACCTACTCCCCGAAGTTACCAGCTCAGCTCGAGTC
TTCAGGGCTGGGCTCCTAGGCTGCCCATCCTACTTCTACCCTCACTGGCCTCCAGTGGGATTCACTCCTGCCCTGCCCCCACCTTCCCAG
TCCCACAGGCCACCCCTGGCTTGGGCTGGGTTCTGTGAAGTTACGTATTTATTGAGCTTTTGGTTCTTTTATAAAGACTTGTCTAGACTC

>96333_96333_1_UBE4B-PLEKHG5_UBE4B_chr1_10093752_ENST00000253251_PLEKHG5_chr1_6537718_ENST00000377732_length(amino acids)=1043AA_BP=3
MEELSADEVCHHADCQQLHRRGPLNLCEACDSKFHSTMHYDGHVRFDLPPQGSVLARNVSTRSCPPRTSPAVDLEEEEEESSVDGKGDRK
STGLKLSKKKARRRHTDDPSKECFTLKFDLNVDIETEIVPAMKKKSLGEVLLPVFERKGIALGKVDIYLDQSNTPLSLTFEAYRFGGHYL
RVKAPAKPGDEGKVEQGMKDSKSLSLPILRPAGTGPPALERVDAQSRRESLDILAPGRRRKNMSEFLGEASIPGQEPPTPSSCSLPSGSS
GSTNTGDSWKNRAASRFSGFFSSGPSTSAFGREVDKMEQLEGKLHTYSLFGLPRLPRGLRFDHDSWEEEYDEDEDEDNACLRLEDSWREL
IDGHEKLTRRQCHQQEAVWELLHTEASYIRKLRVIINLFLCCLLNLQESGLLCEVEAERLFSNIPEIAQLHRRLWASVMAPVLEKARRTR
ALLQPGDFLKGFKMFGSLFKPYIRYCMEEEGCMEYMRGLLRDNDLFRAYITWAEKHPQCQRLKLSDMLAKPHQRLTKYPLLLKSVLRKTE
EPRAKEAVVAMIGSVERFIHHVNACMRQRQERQRLAAVVSRIDAYEVVESSSDEVDKLLKEFLHLDLTAPIPGASPEETRQLLLEGSLRM
KEGKDSKMDVYCFLFTDLLLVTKAVKKAERTRVIRPPLLVDKIVCRELRDPGSFLLIYLNEFHSAVGAYTFQASGQALCRGWVDTIYNAQ
NQLQQLRAQEPPGSQQPLQSLEEEEDEQEEEEEEEEEEEEGEDSGTSAASSPTIMRKSSGSPDSQHCASDGSTETLAMVVVEPGDTLSSP
EFDSGPFSSQSDETSLSTTASSATPTSELLPLGPVDGRSCSMDSAYGTLSPTSLQDFVAPGPMAELVPRAPESPRVPSPPPSPRLRRRTP
VQLLSCPPHLLKSKSEASLLQLLAGAGTHGTPSAPSRSLSELCLAVPAPGIRTQGSPQEAGPSWDCRGAPSPGSGPGLVGCLAGEPAGSH

--------------------------------------------------------------
>96333_96333_2_UBE4B-PLEKHG5_UBE4B_chr1_10093752_ENST00000253251_PLEKHG5_chr1_6537718_ENST00000377740_length(transcript)=3719nt_BP=863nt
GACGGGGTGGGACGGAGGCGGGGAGAGGACGCAGGCGAGAGGAACTCGGCGGCGCGGCGCCCGCGGCCTATTGGCTGCCACGTCCCGGCG
CCAGAAGCCCCGCCTCCCTGACGGGGGTCACGTGATCCCTTTCAAAGATGGCCGCCCTGTTGTTTTGATGAATAATACTTGGTGGGGCGA
GGGGGAAAGAGTAGGGGTGGAGGGGTAGGAGGATTTACTCTTCCAGCGAGAGCTACGCGCATCCCATCCTCCCCCTCCCCCCTACCCGGG
CTCCGGCGTGGAGGCGGGGCGTGGCCGGCCTGCTTTGGGAGGGGAGGGGCTTCCCTTACAGTGCTGGGCTCTGCCAGGACGGCTGTGGGG
TCGCCTTACCTCGGGGTATCCACTCTGCAGTCGACCAGTTCCCGCCAGGAGCAAAGGGTAGGAAGGAGAGCAGGATCTGCTGTAGGAACG
CAGCTACCGCGCCACTATCACGAAGAAACAGCAGGCTCGGGGCACGAGACGAACTGGAGACCGCGCTGCCTAGCTGGGTAACCTGGGAAG
CAGAGGGTAATAAGTGGCGCCTTAAGACAACCCTGTAGCAGCAGCAGTGGCGGCCAAAGGAGGCTGCTCAGGGAACAAGCGGCTGTAGTA
GTCTGTGGGGCGACTGGAGTGACCGAAGCCAAGGCAGTTTAGTGCCTCTCGTGTTCTTATTTTTTAACCTCTGACTATGCAATTCTGAAA
CCTCCCCCATTCGGGGGACCAGACAGCCTGATAGACACCTTCCACTCTCCTTCCTCCCGCCGTGGTCTCGAGAACAGAAGGATCTCTCCT
TAACGCCTTTCACCATTAAGAGGAAAGCGATGGAGGAGCTGAGCGCTGATGAGGTATGTCACCACGCCGACTGCCAGCAGCTGCACCGCC
GGGGGCCCCTCAACCTCTGCGAGGCCTGTGACAGCAAGTTCCACAGCACCATGCATTATGATGGGCATGTCCGCTTCGACCTTCCCCCAC
AAGGCTCTGTGCTGGCCCGGAACGTGTCCACCCGGTCATGCCCGCCGCGCACCAGCCCCGCAGTGGACTTGGAGGAGGAGGAGGAGGAGA
GCTCTGTGGATGGCAAAGGGGACCGGAAGAGCACAGGCCTGAAACTCTCCAAGAAGAAAGCAAGGAGGAGACACACGGATGACCCAAGCA
AGGAATGCTTCACTCTGAAATTTGACCTGAATGTGGACATTGAGACAGAGATCGTCCCAGCCATGAAGAAGAAGTCACTGGGGGAGGTGC
TGCTGCCTGTATTTGAAAGGAAGGGCATTGCGCTGGGCAAAGTGGACATCTACCTGGACCAGTCCAACACACCCCTGTCCCTCACCTTCG
AGGCCTACAGGTTCGGGGGACACTACCTTCGTGTCAAAGCCCCAGCCAAGCCTGGAGATGAGGGCAAGGTGGAGCAGGGCATGAAGGACT
CCAAGTCCCTGAGTTTGCCGATTCTGCGGCCAGCTGGGACCGGGCCCCCCGCCCTGGAGCGTGTGGACGCCCAGAGCCGCCGGGAGAGCC
TGGACATCTTGGCCCCTGGCCGCCGCCGCAAGAACATGTCGGAGTTCCTGGGGGAGGCGAGCATCCCCGGGCAGGAGCCCCCCACGCCCT
CCAGCTGCTCTCTGCCCAGCGGCAGCAGTGGCAGCACCAACACTGGCGACAGCTGGAAGAACCGGGCGGCCAGTCGCTTCAGCGGCTTTT
TCAGCTCCGGCCCCAGCACCAGCGCCTTTGGCCGGGAGGTAGACAAGATGGAGCAGCTGGAGGGCAAGCTGCACACCTACAGCCTCTTCG
GGCTGCCCAGGCTGCCCCGGGGGCTGCGCTTCGACCATGACTCCTGGGAGGAGGAGTACGATGAAGACGAGGATGAGGACAATGCCTGCC
TGAGGCTGGAGGACAGCTGGCGGGAGCTCATTGATGGGCATGAGAAGCTGACCCGGCGGCAGTGCCACCAGCAGGAGGCGGTGTGGGAGC
TGCTGCACACGGAGGCCTCCTACATCAGGAAACTGCGGGTGATCATCAACCTGTTCCTGTGCTGCCTCCTGAACCTGCAAGAGTCAGGGC
TGCTGTGTGAGGTGGAGGCGGAGCGCCTGTTCAGCAACATCCCGGAGATCGCGCAGCTGCACCGCAGGCTGTGGGCTAGCGTGATGGCGC
CGGTGCTGGAGAAGGCGCGGCGCACGCGAGCGCTGCTACAGCCCGGGGACTTCCTCAAAGGCTTCAAGATGTTCGGCTCGCTCTTCAAGC
CCTACATCCGCTACTGCATGGAGGAGGAGGGCTGCATGGAGTACATGCGCGGCCTGCTGCGCGACAACGACCTCTTCCGGGCCTACATCA
CGTGGGCGGAGAAGCACCCACAGTGCCAGAGGCTGAAGCTGAGCGACATGCTGGCCAAACCCCACCAGCGGCTCACCAAGTACCCGCTGC
TGCTCAAGTCGGTGCTGAGGAAGACCGAGGAGCCGCGCGCCAAGGAGGCCGTCGTCGCCATGATCGGCTCCGTGGAGCGCTTCATCCACC
ACGTGAACGCGTGCATGCGGCAGCGGCAGGAGCGGCAGCGGCTGGCGGCCGTGGTGAGCCGCATCGACGCCTACGAGGTGGTGGAAAGCA
GCAGCGACGAAGTGGACAAGCTCCTGAAGGAATTTCTGCACCTGGACTTGACAGCGCCCATCCCTGGCGCCTCCCCGGAGGAGACGCGGC
AGCTGCTGCTGGAGGGGAGCCTGAGGATGAAGGAGGGGAAGGACAGCAAGATGGATGTGTACTGCTTCCTCTTCACGGATCTGCTGTTGG
TGACCAAAGCAGTGAAGAAGGCAGAGAGGACCAGGGTCATCAGGCCACCCCTGCTCGTGGACAAGATTGTGTGCCGGGAGCTACGGGACC
CTGGGTCCTTCCTCCTTATCTACCTGAATGAGTTTCACAGTGCTGTAGGGGCCTACACGTTCCAGGCCAGTGGCCAGGCCTTGTGCCGTG
GCTGGGTGGACACCATTTACAATGCCCAGAACCAGCTGCAACAGCTGCGTGCACAGGAGCCCCCAGGCAGTCAGCAGCCCCTGCAGAGCC
TGGAAGAGGAGGAGGATGAGCAGGAGGAGGAAGAGGAGGAGGAGGAGGAGGAGGAGGAAGGCGAGGACAGTGGCACTTCAGCTGCCAGCT
CCCCTACCATCATGCGGAAAAGCAGCGGCAGCCCCGACTCTCAGCACTGGAAGCTGACCCTGGCCCAGCTCTACCGAATCAGGACCACCC
TGCTGCTTAACTCCACGCTCACTGCCTCGGAGGTCTGAGCAGAGGGAGGCCCCCAAGAGTGCCATTGACCAAGAGACAGCAGACAGCCTG
CCTCCTGGGGCGTGCCGGCACCTGCTTCAGCTACTGCCTCCTGTATGCATGAGCCGGATGCTGGGCAGGATCCCTGCCTACGCCCGGGCC
CGATTTGCGCTTTGCCGGACTGGATGGAGTGGAGGAGGCCCAGGCCACAGTACCACCCCACCTGCCCAGGCAGCCCCTCGTCACCTACTC
CCCGAAGTTACCAGCTCAGCTCGAGTCTTCAGGGCTGGGCTCCTAGGCTGCCCATCCTACTTCTACCCTCACTGGCCTCCAGTGGGATTC
ACTCCTGCCCTGCCCCCACCTTCCCAGTCCCACAGGCCACCCCTGGCTTGGGCTGGGTTCTGTGAAGTTACGTATTTATTGAGCTTTTGG

>96333_96333_2_UBE4B-PLEKHG5_UBE4B_chr1_10093752_ENST00000253251_PLEKHG5_chr1_6537718_ENST00000377740_length(amino acids)=812AA_BP=3
MEELSADEVCHHADCQQLHRRGPLNLCEACDSKFHSTMHYDGHVRFDLPPQGSVLARNVSTRSCPPRTSPAVDLEEEEEESSVDGKGDRK
STGLKLSKKKARRRHTDDPSKECFTLKFDLNVDIETEIVPAMKKKSLGEVLLPVFERKGIALGKVDIYLDQSNTPLSLTFEAYRFGGHYL
RVKAPAKPGDEGKVEQGMKDSKSLSLPILRPAGTGPPALERVDAQSRRESLDILAPGRRRKNMSEFLGEASIPGQEPPTPSSCSLPSGSS
GSTNTGDSWKNRAASRFSGFFSSGPSTSAFGREVDKMEQLEGKLHTYSLFGLPRLPRGLRFDHDSWEEEYDEDEDEDNACLRLEDSWREL
IDGHEKLTRRQCHQQEAVWELLHTEASYIRKLRVIINLFLCCLLNLQESGLLCEVEAERLFSNIPEIAQLHRRLWASVMAPVLEKARRTR
ALLQPGDFLKGFKMFGSLFKPYIRYCMEEEGCMEYMRGLLRDNDLFRAYITWAEKHPQCQRLKLSDMLAKPHQRLTKYPLLLKSVLRKTE
EPRAKEAVVAMIGSVERFIHHVNACMRQRQERQRLAAVVSRIDAYEVVESSSDEVDKLLKEFLHLDLTAPIPGASPEETRQLLLEGSLRM
KEGKDSKMDVYCFLFTDLLLVTKAVKKAERTRVIRPPLLVDKIVCRELRDPGSFLLIYLNEFHSAVGAYTFQASGQALCRGWVDTIYNAQ
NQLQQLRAQEPPGSQQPLQSLEEEEDEQEEEEEEEEEEEEGEDSGTSAASSPTIMRKSSGSPDSQHWKLTLAQLYRIRTTLLLNSTLTAS

--------------------------------------------------------------
>96333_96333_3_UBE4B-PLEKHG5_UBE4B_chr1_10093752_ENST00000253251_PLEKHG5_chr1_6537718_ENST00000377748_length(transcript)=5442nt_BP=863nt
GACGGGGTGGGACGGAGGCGGGGAGAGGACGCAGGCGAGAGGAACTCGGCGGCGCGGCGCCCGCGGCCTATTGGCTGCCACGTCCCGGCG
CCAGAAGCCCCGCCTCCCTGACGGGGGTCACGTGATCCCTTTCAAAGATGGCCGCCCTGTTGTTTTGATGAATAATACTTGGTGGGGCGA
GGGGGAAAGAGTAGGGGTGGAGGGGTAGGAGGATTTACTCTTCCAGCGAGAGCTACGCGCATCCCATCCTCCCCCTCCCCCCTACCCGGG
CTCCGGCGTGGAGGCGGGGCGTGGCCGGCCTGCTTTGGGAGGGGAGGGGCTTCCCTTACAGTGCTGGGCTCTGCCAGGACGGCTGTGGGG
TCGCCTTACCTCGGGGTATCCACTCTGCAGTCGACCAGTTCCCGCCAGGAGCAAAGGGTAGGAAGGAGAGCAGGATCTGCTGTAGGAACG
CAGCTACCGCGCCACTATCACGAAGAAACAGCAGGCTCGGGGCACGAGACGAACTGGAGACCGCGCTGCCTAGCTGGGTAACCTGGGAAG
CAGAGGGTAATAAGTGGCGCCTTAAGACAACCCTGTAGCAGCAGCAGTGGCGGCCAAAGGAGGCTGCTCAGGGAACAAGCGGCTGTAGTA
GTCTGTGGGGCGACTGGAGTGACCGAAGCCAAGGCAGTTTAGTGCCTCTCGTGTTCTTATTTTTTAACCTCTGACTATGCAATTCTGAAA
CCTCCCCCATTCGGGGGACCAGACAGCCTGATAGACACCTTCCACTCTCCTTCCTCCCGCCGTGGTCTCGAGAACAGAAGGATCTCTCCT
TAACGCCTTTCACCATTAAGAGGAAAGCGATGGAGGAGCTGAGCGCTGATGAGGTATGTCACCACGCCGACTGCCAGCAGCTGCACCGCC
GGGGGCCCCTCAACCTCTGCGAGGCCTGTGACAGCAAGTTCCACAGCACCATGCATTATGATGGGCATGTCCGCTTCGACCTTCCCCCAC
AAGGCTCTGTGCTGGCCCGGAACGTGTCCACCCGGTCATGCCCGCCGCGCACCAGCCCCGCAGTGGACTTGGAGGAGGAGGAGGAGGAGA
GCTCTGTGGATGGCAAAGGGGACCGGAAGAGCACAGGCCTGAAACTCTCCAAGAAGAAAGCAAGGAGGAGACACACGGATGACCCAAGCA
AGGAATGCTTCACTCTGAAATTTGACCTGAATGTGGACATTGAGACAGAGATCGTCCCAGCCATGAAGAAGAAGTCACTGGGGGAGGTGC
TGCTGCCTGTATTTGAAAGGAAGGGCATTGCGCTGGGCAAAGTGGACATCTACCTGGACCAGTCCAACACACCCCTGTCCCTCACCTTCG
AGGCCTACAGGTTCGGGGGACACTACCTTCGTGTCAAAGCCCCAGCCAAGCCTGGAGATGAGGGCAAGGTGGAGCAGGGCATGAAGGACT
CCAAGTCCCTGAGTTTGCCGATTCTGCGGCCAGCTGGGACCGGGCCCCCCGCCCTGGAGCGTGTGGACGCCCAGAGCCGCCGGGAGAGCC
TGGACATCTTGGCCCCTGGCCGCCGCCGCAAGAACATGTCGGAGTTCCTGGGGGAGGCGAGCATCCCCGGGCAGGAGCCCCCCACGCCCT
CCAGCTGCTCTCTGCCCAGCGGCAGCAGTGGCAGCACCAACACTGGCGACAGCTGGAAGAACCGGGCGGCCAGTCGCTTCAGCGGCTTTT
TCAGCTCCGGCCCCAGCACCAGCGCCTTTGGCCGGGAGGTAGACAAGATGGAGCAGCTGGAGGGCAAGCTGCACACCTACAGCCTCTTCG
GGCTGCCCAGGCTGCCCCGGGGGCTGCGCTTCGACCATGACTCCTGGGAGGAGGAGTACGATGAAGACGAGGATGAGGACAATGCCTGCC
TGAGGCTGGAGGACAGCTGGCGGGAGCTCATTGATGGGCATGAGAAGCTGACCCGGCGGCAGTGCCACCAGCAGGAGGCGGTGTGGGAGC
TGCTGCACACGGAGGCCTCCTACATCAGGAAACTGCGGGTGATCATCAACCTGTTCCTGTGCTGCCTCCTGAACCTGCAAGAGTCAGGGC
TGCTGTGTGAGGTGGAGGCGGAGCGCCTGTTCAGCAACATCCCGGAGATCGCGCAGCTGCACCGCAGGCTGTGGGCTAGCGTGATGGCGC
CGGTGCTGGAGAAGGCGCGGCGCACGCGAGCGCTGCTACAGCCCGGGGACTTCCTCAAAGGCTTCAAGATGTTCGGCTCGCTCTTCAAGC
CCTACATCCGCTACTGCATGGAGGAGGAGGGCTGCATGGAGTACATGCGCGGCCTGCTGCGCGACAACGACCTCTTCCGGGCCTACATCA
CGTGGGCGGAGAAGCACCCACAGTGCCAGAGGCTGAAGCTGAGCGACATGCTGGCCAAACCCCACCAGCGGCTCACCAAGTACCCGCTGC
TGCTCAAGTCGGTGCTGAGGAAGACCGAGGAGCCGCGCGCCAAGGAGGCCGTCGTCGCCATGATCGGCTCCGTGGAGCGCTTCATCCACC
ACGTGAACGCGTGCATGCGGCAGCGGCAGGAGCGGCAGCGGCTGGCGGCCGTGGTGAGCCGCATCGACGCCTACGAGGTGGTGGAAAGCA
GCAGCGACGAAGTGGACAAGCTCCTGAAGGAATTTCTGCACCTGGACTTGACAGCGCCCATCCCTGGCGCCTCCCCGGAGGAGACGCGGC
AGCTGCTGCTGGAGGGGAGCCTGAGGATGAAGGAGGGGAAGGACAGCAAGATGGATGTGTACTGCTTCCTCTTCACGGATCTGCTGTTGG
TGACCAAAGCAGTGAAGAAGGCAGAGAGGACCAGGGTCATCAGGCCACCCCTGCTCGTGGACAAGATTGTGTGCCGGGAGCTACGGGACC
CTGGGTCCTTCCTCCTTATCTACCTGAATGAGTTTCACAGTGCTGTAGGGGCCTACACGTTCCAGGCCAGTGGCCAGGCCTTGTGCCGTG
GCTGGGTGGACACCATTTACAATGCCCAGAACCAGCTGCAACAGCTGCGTGCACAGGAGCCCCCAGGCAGTCAGCAGCCCCTGCAGAGCC
TGGAAGAGGAGGAGGATGAGCAGGAGGAGGAAGAGGAGGAGGAGGAGGAGGAGGAGGAAGGCGAGGACAGTGGCACTTCAGCTGCCAGCT
CCCCTACCATCATGCGGAAAAGCAGCGGCAGCCCCGACTCTCAGCACTGTGCCTCAGATGGCTCCACGGAGACCCTGGCCATGGTTGTGG
TAGAGCCTGGGGACACGCTGTCCTCCCCCGAGTTCGACAGCGGTCCTTTCAGCTCCCAGTCTGATGAGACCTCTCTCAGCACCACTGCCT
CATCTGCCACGCCCACCAGTGAGCTGCTGCCCCTGGGTCCGGTGGACGGCCGCTCCTGCTCCATGGACTCTGCCTACGGCACCCTCTCCC
CAACCTCCTTACAAGACTTTGTGGCCCCAGGCCCAATGGCAGAGCTAGTGCCTCGGGCCCCAGAGTCCCCACGAGTTCCTTCCCCTCCAC
CCTCGCCCCGTCTCCGCCGCCGCACCCCTGTCCAGCTGTTGAGCTGCCCGCCCCACCTGCTCAAGTCTAAGTCCGAGGCCAGCCTCCTCC
AGCTGCTGGCAGGGGCTGGCACCCATGGGACACCCTCTGCCCCCAGCCGCAGCCTGTCAGAGCTCTGCCTGGCTGTTCCAGCCCCAGGTA
TTAGGACTCAGGGCTCCCCTCAGGAAGCTGGGCCCAGCTGGGATTGCCGAGGGGCCCCTAGCCCTGGCAGCGGTCCTGGGCTAGTCGGCT
GCCTGGCCGGGGAACCTGCAGGCTCCCACAGGAAGAGGTGTGGAGACCTGCCCTCGGGGGCCTCTCCCAGGGTCCAGCCTGAGCCCCCAC
CAGGGGTCTCTGCCCAGCACAGGAAGCTGACCCTGGCCCAGCTCTACCGAATCAGGACCACCCTGCTGCTTAACTCCACGCTCACTGCCT
CGGAGGTCTGAGCAGAGGGAGGCCCCCAAGAGTGCCATTGACCAAGAGACAGCAGACAGCCTGCCTCCTGGGGCGTGCCGGCACCTGCTT
CAGCTACTGCCTCCTGTATGCATGAGCCGGATGCTGGGCAGGATCCCTGCCTACGCCCGGGCCCGATTTGCGCTTTGCCGGACTGGATGG
AGTGGAGGAGGCCCAGGCCACAGTACCACCCCACCTGCCCAGGCAGCCCCTCGTCACCTACTCCCCGAAGTTACCAGCTCAGCTCGAGTC
TTCAGGGCTGGGCTCCTAGGCTGCCCATCCTACTTCTACCCTCACTGGCCTCCAGTGGGATTCACTCCTGCCCTGCCCCCACCTTCCCAG
TCCCACAGGCCACCCCTGGCTTGGGCTGGGTTCTGTGAAGTTACGTATTTATTGAGCTTTTGGTTCTTTTATAAAGACTTGTCTAGACTC
CACTGGGAAGAGTCCTTTGCTTTGGGGCCCAGTGACTCGGGGCACTTGAGTTCAGGGCGGCCTCCTTGTGTTCCTGTGCTCCTCCACTTG
CCACGGATGGGCCACGGATGGAGCTTGCCATGGGAAGCACTGGGAAGTAATGGGGTGTGGGGTGCCACCAGACCAACACCCCCAGACTTC
CCCACCTTCAGCCACCATCAGAGCCTCTCCCCAGGTGCCCCCCGGGGATTCAGGGCTGAATCTGCCCAGTTCCCACACTCAGGCCAGCCC
TCTTGGGAAGGTGGGTCCTCCATGGGGGTCCCTTCAGGAACTTTTTTTTTTTTTTTAATACAGAGTCTCACTCTGTCACCTAGGTTGGAG
TGCAGTGGTGTGATGTCGGCTCACTGCAACCTCTGCCTCCCGGGTTCAAACGATTCTCCTGCCCCAGCCACTCTAGTAGCTGGAACTGCA
GGTGTGCACCACCACGCCGGGCTAGTTTTTGTATTTTAAGTAGAGACGGCATTTCACCATATTGGTCAGGCTGGTCTCGAACTCCTGACC
CCAAGTGTTCCGCCCGCCTCTGCCTCCCATAGTGCTAGAATTACAGGCCTGAGCTACTGCGCTTGGCCCCTTGCGGTACTTTTGGCCCAA
CCTCCTCCATGGCTGGGGACGCGGAGGCCGAGAGAGAAGTCACTTGCCCTGGCTCTACCTTGAAGTGGTTCTCAGGGTTGGGGCGAGAGT
CGGGGTGGGGACCGAGATGCAGCTCTATCCTGTGCCCCTGGTCGCAGCAGGCAGCCCAGCGCTTCGCGTGTTCTACTTGGCCTGTCCGCT
GCCGCCTAATGAGCTCAGGTCTAGGCCGAGCAGAGGGGGCACCTGGTCGGACTCGGTTGGGCTCGGGCGGCCCCGCCTCCCCCCGCCCGC
CAGGCGGGCCCTTCTCGACGGCGCGGGGCGGGCCCTGCGGGCGCGGGGCTGAAGGCGGAACCACGACGGGCAGAGAGCACGGAGCCGGGA

>96333_96333_3_UBE4B-PLEKHG5_UBE4B_chr1_10093752_ENST00000253251_PLEKHG5_chr1_6537718_ENST00000377748_length(amino acids)=1043AA_BP=3
MEELSADEVCHHADCQQLHRRGPLNLCEACDSKFHSTMHYDGHVRFDLPPQGSVLARNVSTRSCPPRTSPAVDLEEEEEESSVDGKGDRK
STGLKLSKKKARRRHTDDPSKECFTLKFDLNVDIETEIVPAMKKKSLGEVLLPVFERKGIALGKVDIYLDQSNTPLSLTFEAYRFGGHYL
RVKAPAKPGDEGKVEQGMKDSKSLSLPILRPAGTGPPALERVDAQSRRESLDILAPGRRRKNMSEFLGEASIPGQEPPTPSSCSLPSGSS
GSTNTGDSWKNRAASRFSGFFSSGPSTSAFGREVDKMEQLEGKLHTYSLFGLPRLPRGLRFDHDSWEEEYDEDEDEDNACLRLEDSWREL
IDGHEKLTRRQCHQQEAVWELLHTEASYIRKLRVIINLFLCCLLNLQESGLLCEVEAERLFSNIPEIAQLHRRLWASVMAPVLEKARRTR
ALLQPGDFLKGFKMFGSLFKPYIRYCMEEEGCMEYMRGLLRDNDLFRAYITWAEKHPQCQRLKLSDMLAKPHQRLTKYPLLLKSVLRKTE
EPRAKEAVVAMIGSVERFIHHVNACMRQRQERQRLAAVVSRIDAYEVVESSSDEVDKLLKEFLHLDLTAPIPGASPEETRQLLLEGSLRM
KEGKDSKMDVYCFLFTDLLLVTKAVKKAERTRVIRPPLLVDKIVCRELRDPGSFLLIYLNEFHSAVGAYTFQASGQALCRGWVDTIYNAQ
NQLQQLRAQEPPGSQQPLQSLEEEEDEQEEEEEEEEEEEEGEDSGTSAASSPTIMRKSSGSPDSQHCASDGSTETLAMVVVEPGDTLSSP
EFDSGPFSSQSDETSLSTTASSATPTSELLPLGPVDGRSCSMDSAYGTLSPTSLQDFVAPGPMAELVPRAPESPRVPSPPPSPRLRRRTP
VQLLSCPPHLLKSKSEASLLQLLAGAGTHGTPSAPSRSLSELCLAVPAPGIRTQGSPQEAGPSWDCRGAPSPGSGPGLVGCLAGEPAGSH

--------------------------------------------------------------
>96333_96333_4_UBE4B-PLEKHG5_UBE4B_chr1_10093752_ENST00000253251_PLEKHG5_chr1_6537718_ENST00000400915_length(transcript)=4412nt_BP=863nt
GACGGGGTGGGACGGAGGCGGGGAGAGGACGCAGGCGAGAGGAACTCGGCGGCGCGGCGCCCGCGGCCTATTGGCTGCCACGTCCCGGCG
CCAGAAGCCCCGCCTCCCTGACGGGGGTCACGTGATCCCTTTCAAAGATGGCCGCCCTGTTGTTTTGATGAATAATACTTGGTGGGGCGA
GGGGGAAAGAGTAGGGGTGGAGGGGTAGGAGGATTTACTCTTCCAGCGAGAGCTACGCGCATCCCATCCTCCCCCTCCCCCCTACCCGGG
CTCCGGCGTGGAGGCGGGGCGTGGCCGGCCTGCTTTGGGAGGGGAGGGGCTTCCCTTACAGTGCTGGGCTCTGCCAGGACGGCTGTGGGG
TCGCCTTACCTCGGGGTATCCACTCTGCAGTCGACCAGTTCCCGCCAGGAGCAAAGGGTAGGAAGGAGAGCAGGATCTGCTGTAGGAACG
CAGCTACCGCGCCACTATCACGAAGAAACAGCAGGCTCGGGGCACGAGACGAACTGGAGACCGCGCTGCCTAGCTGGGTAACCTGGGAAG
CAGAGGGTAATAAGTGGCGCCTTAAGACAACCCTGTAGCAGCAGCAGTGGCGGCCAAAGGAGGCTGCTCAGGGAACAAGCGGCTGTAGTA
GTCTGTGGGGCGACTGGAGTGACCGAAGCCAAGGCAGTTTAGTGCCTCTCGTGTTCTTATTTTTTAACCTCTGACTATGCAATTCTGAAA
CCTCCCCCATTCGGGGGACCAGACAGCCTGATAGACACCTTCCACTCTCCTTCCTCCCGCCGTGGTCTCGAGAACAGAAGGATCTCTCCT
TAACGCCTTTCACCATTAAGAGGAAAGCGATGGAGGAGCTGAGCGCTGATGAGGTATGTCACCACGCCGACTGCCAGCAGCTGCACCGCC
GGGGGCCCCTCAACCTCTGCGAGGCCTGTGACAGCAAGTTCCACAGCACCATGCATTATGATGGGCATGTCCGCTTCGACCTTCCCCCAC
AAGGCTCTGTGCTGGCCCGGAACGTGTCCACCCGGTCATGCCCGCCGCGCACCAGCCCCGCAGTGGACTTGGAGGAGGAGGAGGAGGAGA
GCTCTGTGGATGGCAAAGGGGACCGGAAGAGCACAGGCCTGAAACTCTCCAAGAAGAAAGCAAGGAGGAGACACACGGATGACCCAAGCA
AGGAATGCTTCACTCTGAAATTTGACCTGAATGTGGACATTGAGACAGAGATCGTCCCAGCCATGAAGAAGAAGTCACTGGGGGAGGTGC
TGCTGCCTGTATTTGAAAGGAAGGGCATTGCGCTGGGCAAAGTGGACATCTACCTGGACCAGTCCAACACACCCCTGTCCCTCACCTTCG
AGGCCTACAGGTTCGGGGGACACTACCTTCGTGTCAAAGCCCCAGCCAAGCCTGGAGATGAGGGCAAGGTGGAGCAGGGCATGAAGGACT
CCAAGTCCCTGAGTTTGCCGATTCTGCGGCCAGCTGGGACCGGGCCCCCCGCCCTGGAGCGTGTGGACGCCCAGAGCCGCCGGGAGAGCC
TGGACATCTTGGCCCCTGGCCGCCGCCGCAAGAACATGTCGGAGTTCCTGGGGGAGGCGAGCATCCCCGGGCAGGAGCCCCCCACGCCCT
CCAGCTGCTCTCTGCCCAGCGGCAGCAGTGGCAGCACCAACACTGGCGACAGCTGGAAGAACCGGGCGGCCAGTCGCTTCAGCGGCTTTT
TCAGCTCCGGCCCCAGCACCAGCGCCTTTGGCCGGGAGGTAGACAAGATGGAGCAGCTGGAGGGCAAGCTGCACACCTACAGCCTCTTCG
GGCTGCCCAGGCTGCCCCGGGGGCTGCGCTTCGACCATGACTCCTGGGAGGAGGAGTACGATGAAGACGAGGATGAGGACAATGCCTGCC
TGAGGCTGGAGGACAGCTGGCGGGAGCTCATTGATGGGCATGAGAAGCTGACCCGGCGGCAGTGCCACCAGCAGGAGGCGGTGTGGGAGC
TGCTGCACACGGAGGCCTCCTACATCAGGAAACTGCGGGTGATCATCAACCTGTTCCTGTGCTGCCTCCTGAACCTGCAAGAGTCAGGGC
TGCTGTGTGAGGTGGAGGCGGAGCGCCTGTTCAGCAACATCCCGGAGATCGCGCAGCTGCACCGCAGGCTGTGGGCTAGCGTGATGGCGC
CGGTGCTGGAGAAGGCGCGGCGCACGCGAGCGCTGCTACAGCCCGGGGACTTCCTCAAAGGCTTCAAGATGTTCGGCTCGCTCTTCAAGC
CCTACATCCGCTACTGCATGGAGGAGGAGGGCTGCATGGAGTACATGCGCGGCCTGCTGCGCGACAACGACCTCTTCCGGGCCTACATCA
CGTGGGCGGAGAAGCACCCACAGTGCCAGAGGCTGAAGCTGAGCGACATGCTGGCCAAACCCCACCAGCGGCTCACCAAGTACCCGCTGC
TGCTCAAGTCGGTGCTGAGGAAGACCGAGGAGCCGCGCGCCAAGGAGGCCGTCGTCGCCATGATCGGCTCCGTGGAGCGCTTCATCCACC
ACGTGAACGCGTGCATGCGGCAGCGGCAGGAGCGGCAGCGGCTGGCGGCCGTGGTGAGCCGCATCGACGCCTACGAGGTGGTGGAAAGCA
GCAGCGACGAAGTGGACAAGCTCCTGAAGGAATTTCTGCACCTGGACTTGACAGCGCCCATCCCTGGCGCCTCCCCGGAGGAGACGCGGC
AGCTGCTGCTGGAGGGGAGCCTGAGGATGAAGGAGGGGAAGGACAGCAAGATGGATGTGTACTGCTTCCTCTTCACGGATCTGCTGTTGG
TGACCAAAGCAGTGAAGAAGGCAGAGAGGACCAGGGTCATCAGGCCACCCCTGCTCGTGGACAAGATTGTGTGCCGGGAGCTACGGGACC
CTGGGTCCTTCCTCCTTATCTACCTGAATGAGTTTCACAGTGCTGTAGGGGCCTACACGTTCCAGGCCAGTGGCCAGGCCTTGTGCCGTG
GCTGGGTGGACACCATTTACAATGCCCAGAACCAGCTGCAACAGCTGCGTGCACAGGAGCCCCCAGGCAGTCAGCAGCCCCTGCAGAGCC
TGGAAGAGGAGGAGGATGAGCAGGAGGAGGAAGAGGAGGAGGAGGAGGAGGAGGAGGAAGGCGAGGACAGTGGCACTTCAGCTGCCAGCT
CCCCTACCATCATGCGGAAAAGCAGCGGCAGCCCCGACTCTCAGCACTGTGCCTCAGATGGCTCCACGGAGACCCTGGCCATGGTTGTGG
TAGAGCCTGGGGACACGCTGTCCTCCCCCGAGTTCGACAGCGGTCCTTTCAGCTCCCAGTCTGATGAGACCTCTCTCAGCACCACTGCCT
CATCTGCCACGCCCACCAGTGAGCTGCTGCCCCTGGGTCCGGTGGACGGCCGCTCCTGCTCCATGGACTCTGCCTACGGCACCCTCTCCC
CAACCTCCTTACAAGACTTTGTGGCCCCAGGCCCAATGGCAGAGCTAGTGCCTCGGGCCCCAGAGTCCCCACGAGTTCCTTCCCCTCCAC
CCTCGCCCCGTCTCCGCCGCCGCACCCCTGTCCAGCTGTTGAGCTGCCCGCCCCACCTGCTCAAGTCTAAGTCCGAGGCCAGCCTCCTCC
AGCTGCTGGCAGGGGCTGGCACCCATGGGACACCCTCTGCCCCCAGCCGCAGCCTGTCAGAGCTCTGCCTGGCTGTTCCAGCCCCAGGTA
TTAGGACTCAGGGCTCCCCTCAGGAAGCTGGGCCCAGCTGGGATTGCCGAGGGGCCCCTAGCCCTGGCAGCGGTCCTGGGCTAGTCGGCT
GCCTGGCCGGGGAACCTGCAGGCTCCCACAGGAAGAGGTGTGGAGACCTGCCCTCGGGGGCCTCTCCCAGGGTCCAGCCTGAGCCCCCAC
CAGGGGTCTCTGCCCAGCACAGGAAGCTGACCCTGGCCCAGCTCTACCGAATCAGGACCACCCTGCTGCTTAACTCCACGCTCACTGCCT
CGGAGGTCTGAGCAGAGGGAGGCCCCCAAGAGTGCCATTGACCAAGAGACAGCAGACAGCCTGCCTCCTGGGGCGTGCCGGCACCTGCTT
CAGCTACTGCCTCCTGTATGCATGAGCCGGATGCTGGGCAGGATCCCTGCCTACGCCCGGGCCCGATTTGCGCTTTGCCGGACTGGATGG
AGTGGAGGAGGCCCAGGCCACAGTACCACCCCACCTGCCCAGGCAGCCCCTCGTCACCTACTCCCCGAAGTTACCAGCTCAGCTCGAGTC
TTCAGGGCTGGGCTCCTAGGCTGCCCATCCTACTTCTACCCTCACTGGCCTCCAGTGGGATTCACTCCTGCCCTGCCCCCACCTTCCCAG
TCCCACAGGCCACCCCTGGCTTGGGCTGGGTTCTGTGAAGTTACGTATTTATTGAGCTTTTGGTTCTTTTATAAAGACTTGTCTAGACTC

>96333_96333_4_UBE4B-PLEKHG5_UBE4B_chr1_10093752_ENST00000253251_PLEKHG5_chr1_6537718_ENST00000400915_length(amino acids)=1043AA_BP=3
MEELSADEVCHHADCQQLHRRGPLNLCEACDSKFHSTMHYDGHVRFDLPPQGSVLARNVSTRSCPPRTSPAVDLEEEEEESSVDGKGDRK
STGLKLSKKKARRRHTDDPSKECFTLKFDLNVDIETEIVPAMKKKSLGEVLLPVFERKGIALGKVDIYLDQSNTPLSLTFEAYRFGGHYL
RVKAPAKPGDEGKVEQGMKDSKSLSLPILRPAGTGPPALERVDAQSRRESLDILAPGRRRKNMSEFLGEASIPGQEPPTPSSCSLPSGSS
GSTNTGDSWKNRAASRFSGFFSSGPSTSAFGREVDKMEQLEGKLHTYSLFGLPRLPRGLRFDHDSWEEEYDEDEDEDNACLRLEDSWREL
IDGHEKLTRRQCHQQEAVWELLHTEASYIRKLRVIINLFLCCLLNLQESGLLCEVEAERLFSNIPEIAQLHRRLWASVMAPVLEKARRTR
ALLQPGDFLKGFKMFGSLFKPYIRYCMEEEGCMEYMRGLLRDNDLFRAYITWAEKHPQCQRLKLSDMLAKPHQRLTKYPLLLKSVLRKTE
EPRAKEAVVAMIGSVERFIHHVNACMRQRQERQRLAAVVSRIDAYEVVESSSDEVDKLLKEFLHLDLTAPIPGASPEETRQLLLEGSLRM
KEGKDSKMDVYCFLFTDLLLVTKAVKKAERTRVIRPPLLVDKIVCRELRDPGSFLLIYLNEFHSAVGAYTFQASGQALCRGWVDTIYNAQ
NQLQQLRAQEPPGSQQPLQSLEEEEDEQEEEEEEEEEEEEGEDSGTSAASSPTIMRKSSGSPDSQHCASDGSTETLAMVVVEPGDTLSSP
EFDSGPFSSQSDETSLSTTASSATPTSELLPLGPVDGRSCSMDSAYGTLSPTSLQDFVAPGPMAELVPRAPESPRVPSPPPSPRLRRRTP
VQLLSCPPHLLKSKSEASLLQLLAGAGTHGTPSAPSRSLSELCLAVPAPGIRTQGSPQEAGPSWDCRGAPSPGSGPGLVGCLAGEPAGSH

--------------------------------------------------------------
>96333_96333_5_UBE4B-PLEKHG5_UBE4B_chr1_10093752_ENST00000343090_PLEKHG5_chr1_6537718_ENST00000377732_length(transcript)=3648nt_BP=99nt
CTCTCCTTCCTCCCGCCGTGGTCTCGAGAACAGAAGGATCTCTCCTTAACGCCTTTCACCATTAAGAGGAAAGCGATGGAGGAGCTGAGC
GCTGATGAGGTATGTCACCACGCCGACTGCCAGCAGCTGCACCGCCGGGGGCCCCTCAACCTCTGCGAGGCCTGTGACAGCAAGTTCCAC
AGCACCATGCATTATGATGGGCATGTCCGCTTCGACCTTCCCCCACAAGGCTCTGTGCTGGCCCGGAACGTGTCCACCCGGTCATGCCCG
CCGCGCACCAGCCCCGCAGTGGACTTGGAGGAGGAGGAGGAGGAGAGCTCTGTGGATGGCAAAGGGGACCGGAAGAGCACAGGCCTGAAA
CTCTCCAAGAAGAAAGCAAGGAGGAGACACACGGATGACCCAAGCAAGGAATGCTTCACTCTGAAATTTGACCTGAATGTGGACATTGAG
ACAGAGATCGTCCCAGCCATGAAGAAGAAGTCACTGGGGGAGGTGCTGCTGCCTGTATTTGAAAGGAAGGGCATTGCGCTGGGCAAAGTG
GACATCTACCTGGACCAGTCCAACACACCCCTGTCCCTCACCTTCGAGGCCTACAGGTTCGGGGGACACTACCTTCGTGTCAAAGCCCCA
GCCAAGCCTGGAGATGAGGGCAAGGTGGAGCAGGGCATGAAGGACTCCAAGTCCCTGAGTTTGCCGATTCTGCGGCCAGCTGGGACCGGG
CCCCCCGCCCTGGAGCGTGTGGACGCCCAGAGCCGCCGGGAGAGCCTGGACATCTTGGCCCCTGGCCGCCGCCGCAAGAACATGTCGGAG
TTCCTGGGGGAGGCGAGCATCCCCGGGCAGGAGCCCCCCACGCCCTCCAGCTGCTCTCTGCCCAGCGGCAGCAGTGGCAGCACCAACACT
GGCGACAGCTGGAAGAACCGGGCGGCCAGTCGCTTCAGCGGCTTTTTCAGCTCCGGCCCCAGCACCAGCGCCTTTGGCCGGGAGGTAGAC
AAGATGGAGCAGCTGGAGGGCAAGCTGCACACCTACAGCCTCTTCGGGCTGCCCAGGCTGCCCCGGGGGCTGCGCTTCGACCATGACTCC
TGGGAGGAGGAGTACGATGAAGACGAGGATGAGGACAATGCCTGCCTGAGGCTGGAGGACAGCTGGCGGGAGCTCATTGATGGGCATGAG
AAGCTGACCCGGCGGCAGTGCCACCAGCAGGAGGCGGTGTGGGAGCTGCTGCACACGGAGGCCTCCTACATCAGGAAACTGCGGGTGATC
ATCAACCTGTTCCTGTGCTGCCTCCTGAACCTGCAAGAGTCAGGGCTGCTGTGTGAGGTGGAGGCGGAGCGCCTGTTCAGCAACATCCCG
GAGATCGCGCAGCTGCACCGCAGGCTGTGGGCTAGCGTGATGGCGCCGGTGCTGGAGAAGGCGCGGCGCACGCGAGCGCTGCTACAGCCC
GGGGACTTCCTCAAAGGCTTCAAGATGTTCGGCTCGCTCTTCAAGCCCTACATCCGCTACTGCATGGAGGAGGAGGGCTGCATGGAGTAC
ATGCGCGGCCTGCTGCGCGACAACGACCTCTTCCGGGCCTACATCACGTGGGCGGAGAAGCACCCACAGTGCCAGAGGCTGAAGCTGAGC
GACATGCTGGCCAAACCCCACCAGCGGCTCACCAAGTACCCGCTGCTGCTCAAGTCGGTGCTGAGGAAGACCGAGGAGCCGCGCGCCAAG
GAGGCCGTCGTCGCCATGATCGGCTCCGTGGAGCGCTTCATCCACCACGTGAACGCGTGCATGCGGCAGCGGCAGGAGCGGCAGCGGCTG
GCGGCCGTGGTGAGCCGCATCGACGCCTACGAGGTGGTGGAAAGCAGCAGCGACGAAGTGGACAAGCTCCTGAAGGAATTTCTGCACCTG
GACTTGACAGCGCCCATCCCTGGCGCCTCCCCGGAGGAGACGCGGCAGCTGCTGCTGGAGGGGAGCCTGAGGATGAAGGAGGGGAAGGAC
AGCAAGATGGATGTGTACTGCTTCCTCTTCACGGATCTGCTGTTGGTGACCAAAGCAGTGAAGAAGGCAGAGAGGACCAGGGTCATCAGG
CCACCCCTGCTCGTGGACAAGATTGTGTGCCGGGAGCTACGGGACCCTGGGTCCTTCCTCCTTATCTACCTGAATGAGTTTCACAGTGCT
GTAGGGGCCTACACGTTCCAGGCCAGTGGCCAGGCCTTGTGCCGTGGCTGGGTGGACACCATTTACAATGCCCAGAACCAGCTGCAACAG
CTGCGTGCACAGGAGCCCCCAGGCAGTCAGCAGCCCCTGCAGAGCCTGGAAGAGGAGGAGGATGAGCAGGAGGAGGAAGAGGAGGAGGAG
GAGGAGGAGGAGGAAGGCGAGGACAGTGGCACTTCAGCTGCCAGCTCCCCTACCATCATGCGGAAAAGCAGCGGCAGCCCCGACTCTCAG
CACTGTGCCTCAGATGGCTCCACGGAGACCCTGGCCATGGTTGTGGTAGAGCCTGGGGACACGCTGTCCTCCCCCGAGTTCGACAGCGGT
CCTTTCAGCTCCCAGTCTGATGAGACCTCTCTCAGCACCACTGCCTCATCTGCCACGCCCACCAGTGAGCTGCTGCCCCTGGGTCCGGTG
GACGGCCGCTCCTGCTCCATGGACTCTGCCTACGGCACCCTCTCCCCAACCTCCTTACAAGACTTTGTGGCCCCAGGCCCAATGGCAGAG
CTAGTGCCTCGGGCCCCAGAGTCCCCACGAGTTCCTTCCCCTCCACCCTCGCCCCGTCTCCGCCGCCGCACCCCTGTCCAGCTGTTGAGC
TGCCCGCCCCACCTGCTCAAGTCTAAGTCCGAGGCCAGCCTCCTCCAGCTGCTGGCAGGGGCTGGCACCCATGGGACACCCTCTGCCCCC
AGCCGCAGCCTGTCAGAGCTCTGCCTGGCTGTTCCAGCCCCAGGTATTAGGACTCAGGGCTCCCCTCAGGAAGCTGGGCCCAGCTGGGAT
TGCCGAGGGGCCCCTAGCCCTGGCAGCGGTCCTGGGCTAGTCGGCTGCCTGGCCGGGGAACCTGCAGGCTCCCACAGGAAGAGGTGTGGA
GACCTGCCCTCGGGGGCCTCTCCCAGGGTCCAGCCTGAGCCCCCACCAGGGGTCTCTGCCCAGCACAGGAAGCTGACCCTGGCCCAGCTC
TACCGAATCAGGACCACCCTGCTGCTTAACTCCACGCTCACTGCCTCGGAGGTCTGAGCAGAGGGAGGCCCCCAAGAGTGCCATTGACCA
AGAGACAGCAGACAGCCTGCCTCCTGGGGCGTGCCGGCACCTGCTTCAGCTACTGCCTCCTGTATGCATGAGCCGGATGCTGGGCAGGAT
CCCTGCCTACGCCCGGGCCCGATTTGCGCTTTGCCGGACTGGATGGAGTGGAGGAGGCCCAGGCCACAGTACCACCCCACCTGCCCAGGC
AGCCCCTCGTCACCTACTCCCCGAAGTTACCAGCTCAGCTCGAGTCTTCAGGGCTGGGCTCCTAGGCTGCCCATCCTACTTCTACCCTCA
CTGGCCTCCAGTGGGATTCACTCCTGCCCTGCCCCCACCTTCCCAGTCCCACAGGCCACCCCTGGCTTGGGCTGGGTTCTGTGAAGTTAC

>96333_96333_5_UBE4B-PLEKHG5_UBE4B_chr1_10093752_ENST00000343090_PLEKHG5_chr1_6537718_ENST00000377732_length(amino acids)=1043AA_BP=3
MEELSADEVCHHADCQQLHRRGPLNLCEACDSKFHSTMHYDGHVRFDLPPQGSVLARNVSTRSCPPRTSPAVDLEEEEEESSVDGKGDRK
STGLKLSKKKARRRHTDDPSKECFTLKFDLNVDIETEIVPAMKKKSLGEVLLPVFERKGIALGKVDIYLDQSNTPLSLTFEAYRFGGHYL
RVKAPAKPGDEGKVEQGMKDSKSLSLPILRPAGTGPPALERVDAQSRRESLDILAPGRRRKNMSEFLGEASIPGQEPPTPSSCSLPSGSS
GSTNTGDSWKNRAASRFSGFFSSGPSTSAFGREVDKMEQLEGKLHTYSLFGLPRLPRGLRFDHDSWEEEYDEDEDEDNACLRLEDSWREL
IDGHEKLTRRQCHQQEAVWELLHTEASYIRKLRVIINLFLCCLLNLQESGLLCEVEAERLFSNIPEIAQLHRRLWASVMAPVLEKARRTR
ALLQPGDFLKGFKMFGSLFKPYIRYCMEEEGCMEYMRGLLRDNDLFRAYITWAEKHPQCQRLKLSDMLAKPHQRLTKYPLLLKSVLRKTE
EPRAKEAVVAMIGSVERFIHHVNACMRQRQERQRLAAVVSRIDAYEVVESSSDEVDKLLKEFLHLDLTAPIPGASPEETRQLLLEGSLRM
KEGKDSKMDVYCFLFTDLLLVTKAVKKAERTRVIRPPLLVDKIVCRELRDPGSFLLIYLNEFHSAVGAYTFQASGQALCRGWVDTIYNAQ
NQLQQLRAQEPPGSQQPLQSLEEEEDEQEEEEEEEEEEEEGEDSGTSAASSPTIMRKSSGSPDSQHCASDGSTETLAMVVVEPGDTLSSP
EFDSGPFSSQSDETSLSTTASSATPTSELLPLGPVDGRSCSMDSAYGTLSPTSLQDFVAPGPMAELVPRAPESPRVPSPPPSPRLRRRTP
VQLLSCPPHLLKSKSEASLLQLLAGAGTHGTPSAPSRSLSELCLAVPAPGIRTQGSPQEAGPSWDCRGAPSPGSGPGLVGCLAGEPAGSH

--------------------------------------------------------------
>96333_96333_6_UBE4B-PLEKHG5_UBE4B_chr1_10093752_ENST00000343090_PLEKHG5_chr1_6537718_ENST00000377740_length(transcript)=2955nt_BP=99nt
CTCTCCTTCCTCCCGCCGTGGTCTCGAGAACAGAAGGATCTCTCCTTAACGCCTTTCACCATTAAGAGGAAAGCGATGGAGGAGCTGAGC
GCTGATGAGGTATGTCACCACGCCGACTGCCAGCAGCTGCACCGCCGGGGGCCCCTCAACCTCTGCGAGGCCTGTGACAGCAAGTTCCAC
AGCACCATGCATTATGATGGGCATGTCCGCTTCGACCTTCCCCCACAAGGCTCTGTGCTGGCCCGGAACGTGTCCACCCGGTCATGCCCG
CCGCGCACCAGCCCCGCAGTGGACTTGGAGGAGGAGGAGGAGGAGAGCTCTGTGGATGGCAAAGGGGACCGGAAGAGCACAGGCCTGAAA
CTCTCCAAGAAGAAAGCAAGGAGGAGACACACGGATGACCCAAGCAAGGAATGCTTCACTCTGAAATTTGACCTGAATGTGGACATTGAG
ACAGAGATCGTCCCAGCCATGAAGAAGAAGTCACTGGGGGAGGTGCTGCTGCCTGTATTTGAAAGGAAGGGCATTGCGCTGGGCAAAGTG
GACATCTACCTGGACCAGTCCAACACACCCCTGTCCCTCACCTTCGAGGCCTACAGGTTCGGGGGACACTACCTTCGTGTCAAAGCCCCA
GCCAAGCCTGGAGATGAGGGCAAGGTGGAGCAGGGCATGAAGGACTCCAAGTCCCTGAGTTTGCCGATTCTGCGGCCAGCTGGGACCGGG
CCCCCCGCCCTGGAGCGTGTGGACGCCCAGAGCCGCCGGGAGAGCCTGGACATCTTGGCCCCTGGCCGCCGCCGCAAGAACATGTCGGAG
TTCCTGGGGGAGGCGAGCATCCCCGGGCAGGAGCCCCCCACGCCCTCCAGCTGCTCTCTGCCCAGCGGCAGCAGTGGCAGCACCAACACT
GGCGACAGCTGGAAGAACCGGGCGGCCAGTCGCTTCAGCGGCTTTTTCAGCTCCGGCCCCAGCACCAGCGCCTTTGGCCGGGAGGTAGAC
AAGATGGAGCAGCTGGAGGGCAAGCTGCACACCTACAGCCTCTTCGGGCTGCCCAGGCTGCCCCGGGGGCTGCGCTTCGACCATGACTCC
TGGGAGGAGGAGTACGATGAAGACGAGGATGAGGACAATGCCTGCCTGAGGCTGGAGGACAGCTGGCGGGAGCTCATTGATGGGCATGAG
AAGCTGACCCGGCGGCAGTGCCACCAGCAGGAGGCGGTGTGGGAGCTGCTGCACACGGAGGCCTCCTACATCAGGAAACTGCGGGTGATC
ATCAACCTGTTCCTGTGCTGCCTCCTGAACCTGCAAGAGTCAGGGCTGCTGTGTGAGGTGGAGGCGGAGCGCCTGTTCAGCAACATCCCG
GAGATCGCGCAGCTGCACCGCAGGCTGTGGGCTAGCGTGATGGCGCCGGTGCTGGAGAAGGCGCGGCGCACGCGAGCGCTGCTACAGCCC
GGGGACTTCCTCAAAGGCTTCAAGATGTTCGGCTCGCTCTTCAAGCCCTACATCCGCTACTGCATGGAGGAGGAGGGCTGCATGGAGTAC
ATGCGCGGCCTGCTGCGCGACAACGACCTCTTCCGGGCCTACATCACGTGGGCGGAGAAGCACCCACAGTGCCAGAGGCTGAAGCTGAGC
GACATGCTGGCCAAACCCCACCAGCGGCTCACCAAGTACCCGCTGCTGCTCAAGTCGGTGCTGAGGAAGACCGAGGAGCCGCGCGCCAAG
GAGGCCGTCGTCGCCATGATCGGCTCCGTGGAGCGCTTCATCCACCACGTGAACGCGTGCATGCGGCAGCGGCAGGAGCGGCAGCGGCTG
GCGGCCGTGGTGAGCCGCATCGACGCCTACGAGGTGGTGGAAAGCAGCAGCGACGAAGTGGACAAGCTCCTGAAGGAATTTCTGCACCTG
GACTTGACAGCGCCCATCCCTGGCGCCTCCCCGGAGGAGACGCGGCAGCTGCTGCTGGAGGGGAGCCTGAGGATGAAGGAGGGGAAGGAC
AGCAAGATGGATGTGTACTGCTTCCTCTTCACGGATCTGCTGTTGGTGACCAAAGCAGTGAAGAAGGCAGAGAGGACCAGGGTCATCAGG
CCACCCCTGCTCGTGGACAAGATTGTGTGCCGGGAGCTACGGGACCCTGGGTCCTTCCTCCTTATCTACCTGAATGAGTTTCACAGTGCT
GTAGGGGCCTACACGTTCCAGGCCAGTGGCCAGGCCTTGTGCCGTGGCTGGGTGGACACCATTTACAATGCCCAGAACCAGCTGCAACAG
CTGCGTGCACAGGAGCCCCCAGGCAGTCAGCAGCCCCTGCAGAGCCTGGAAGAGGAGGAGGATGAGCAGGAGGAGGAAGAGGAGGAGGAG
GAGGAGGAGGAGGAAGGCGAGGACAGTGGCACTTCAGCTGCCAGCTCCCCTACCATCATGCGGAAAAGCAGCGGCAGCCCCGACTCTCAG
CACTGGAAGCTGACCCTGGCCCAGCTCTACCGAATCAGGACCACCCTGCTGCTTAACTCCACGCTCACTGCCTCGGAGGTCTGAGCAGAG
GGAGGCCCCCAAGAGTGCCATTGACCAAGAGACAGCAGACAGCCTGCCTCCTGGGGCGTGCCGGCACCTGCTTCAGCTACTGCCTCCTGT
ATGCATGAGCCGGATGCTGGGCAGGATCCCTGCCTACGCCCGGGCCCGATTTGCGCTTTGCCGGACTGGATGGAGTGGAGGAGGCCCAGG
CCACAGTACCACCCCACCTGCCCAGGCAGCCCCTCGTCACCTACTCCCCGAAGTTACCAGCTCAGCTCGAGTCTTCAGGGCTGGGCTCCT
AGGCTGCCCATCCTACTTCTACCCTCACTGGCCTCCAGTGGGATTCACTCCTGCCCTGCCCCCACCTTCCCAGTCCCACAGGCCACCCCT

>96333_96333_6_UBE4B-PLEKHG5_UBE4B_chr1_10093752_ENST00000343090_PLEKHG5_chr1_6537718_ENST00000377740_length(amino acids)=812AA_BP=3
MEELSADEVCHHADCQQLHRRGPLNLCEACDSKFHSTMHYDGHVRFDLPPQGSVLARNVSTRSCPPRTSPAVDLEEEEEESSVDGKGDRK
STGLKLSKKKARRRHTDDPSKECFTLKFDLNVDIETEIVPAMKKKSLGEVLLPVFERKGIALGKVDIYLDQSNTPLSLTFEAYRFGGHYL
RVKAPAKPGDEGKVEQGMKDSKSLSLPILRPAGTGPPALERVDAQSRRESLDILAPGRRRKNMSEFLGEASIPGQEPPTPSSCSLPSGSS
GSTNTGDSWKNRAASRFSGFFSSGPSTSAFGREVDKMEQLEGKLHTYSLFGLPRLPRGLRFDHDSWEEEYDEDEDEDNACLRLEDSWREL
IDGHEKLTRRQCHQQEAVWELLHTEASYIRKLRVIINLFLCCLLNLQESGLLCEVEAERLFSNIPEIAQLHRRLWASVMAPVLEKARRTR
ALLQPGDFLKGFKMFGSLFKPYIRYCMEEEGCMEYMRGLLRDNDLFRAYITWAEKHPQCQRLKLSDMLAKPHQRLTKYPLLLKSVLRKTE
EPRAKEAVVAMIGSVERFIHHVNACMRQRQERQRLAAVVSRIDAYEVVESSSDEVDKLLKEFLHLDLTAPIPGASPEETRQLLLEGSLRM
KEGKDSKMDVYCFLFTDLLLVTKAVKKAERTRVIRPPLLVDKIVCRELRDPGSFLLIYLNEFHSAVGAYTFQASGQALCRGWVDTIYNAQ
NQLQQLRAQEPPGSQQPLQSLEEEEDEQEEEEEEEEEEEEGEDSGTSAASSPTIMRKSSGSPDSQHWKLTLAQLYRIRTTLLLNSTLTAS

--------------------------------------------------------------
>96333_96333_7_UBE4B-PLEKHG5_UBE4B_chr1_10093752_ENST00000343090_PLEKHG5_chr1_6537718_ENST00000377748_length(transcript)=4678nt_BP=99nt
CTCTCCTTCCTCCCGCCGTGGTCTCGAGAACAGAAGGATCTCTCCTTAACGCCTTTCACCATTAAGAGGAAAGCGATGGAGGAGCTGAGC
GCTGATGAGGTATGTCACCACGCCGACTGCCAGCAGCTGCACCGCCGGGGGCCCCTCAACCTCTGCGAGGCCTGTGACAGCAAGTTCCAC
AGCACCATGCATTATGATGGGCATGTCCGCTTCGACCTTCCCCCACAAGGCTCTGTGCTGGCCCGGAACGTGTCCACCCGGTCATGCCCG
CCGCGCACCAGCCCCGCAGTGGACTTGGAGGAGGAGGAGGAGGAGAGCTCTGTGGATGGCAAAGGGGACCGGAAGAGCACAGGCCTGAAA
CTCTCCAAGAAGAAAGCAAGGAGGAGACACACGGATGACCCAAGCAAGGAATGCTTCACTCTGAAATTTGACCTGAATGTGGACATTGAG
ACAGAGATCGTCCCAGCCATGAAGAAGAAGTCACTGGGGGAGGTGCTGCTGCCTGTATTTGAAAGGAAGGGCATTGCGCTGGGCAAAGTG
GACATCTACCTGGACCAGTCCAACACACCCCTGTCCCTCACCTTCGAGGCCTACAGGTTCGGGGGACACTACCTTCGTGTCAAAGCCCCA
GCCAAGCCTGGAGATGAGGGCAAGGTGGAGCAGGGCATGAAGGACTCCAAGTCCCTGAGTTTGCCGATTCTGCGGCCAGCTGGGACCGGG
CCCCCCGCCCTGGAGCGTGTGGACGCCCAGAGCCGCCGGGAGAGCCTGGACATCTTGGCCCCTGGCCGCCGCCGCAAGAACATGTCGGAG
TTCCTGGGGGAGGCGAGCATCCCCGGGCAGGAGCCCCCCACGCCCTCCAGCTGCTCTCTGCCCAGCGGCAGCAGTGGCAGCACCAACACT
GGCGACAGCTGGAAGAACCGGGCGGCCAGTCGCTTCAGCGGCTTTTTCAGCTCCGGCCCCAGCACCAGCGCCTTTGGCCGGGAGGTAGAC
AAGATGGAGCAGCTGGAGGGCAAGCTGCACACCTACAGCCTCTTCGGGCTGCCCAGGCTGCCCCGGGGGCTGCGCTTCGACCATGACTCC
TGGGAGGAGGAGTACGATGAAGACGAGGATGAGGACAATGCCTGCCTGAGGCTGGAGGACAGCTGGCGGGAGCTCATTGATGGGCATGAG
AAGCTGACCCGGCGGCAGTGCCACCAGCAGGAGGCGGTGTGGGAGCTGCTGCACACGGAGGCCTCCTACATCAGGAAACTGCGGGTGATC
ATCAACCTGTTCCTGTGCTGCCTCCTGAACCTGCAAGAGTCAGGGCTGCTGTGTGAGGTGGAGGCGGAGCGCCTGTTCAGCAACATCCCG
GAGATCGCGCAGCTGCACCGCAGGCTGTGGGCTAGCGTGATGGCGCCGGTGCTGGAGAAGGCGCGGCGCACGCGAGCGCTGCTACAGCCC
GGGGACTTCCTCAAAGGCTTCAAGATGTTCGGCTCGCTCTTCAAGCCCTACATCCGCTACTGCATGGAGGAGGAGGGCTGCATGGAGTAC
ATGCGCGGCCTGCTGCGCGACAACGACCTCTTCCGGGCCTACATCACGTGGGCGGAGAAGCACCCACAGTGCCAGAGGCTGAAGCTGAGC
GACATGCTGGCCAAACCCCACCAGCGGCTCACCAAGTACCCGCTGCTGCTCAAGTCGGTGCTGAGGAAGACCGAGGAGCCGCGCGCCAAG
GAGGCCGTCGTCGCCATGATCGGCTCCGTGGAGCGCTTCATCCACCACGTGAACGCGTGCATGCGGCAGCGGCAGGAGCGGCAGCGGCTG
GCGGCCGTGGTGAGCCGCATCGACGCCTACGAGGTGGTGGAAAGCAGCAGCGACGAAGTGGACAAGCTCCTGAAGGAATTTCTGCACCTG
GACTTGACAGCGCCCATCCCTGGCGCCTCCCCGGAGGAGACGCGGCAGCTGCTGCTGGAGGGGAGCCTGAGGATGAAGGAGGGGAAGGAC
AGCAAGATGGATGTGTACTGCTTCCTCTTCACGGATCTGCTGTTGGTGACCAAAGCAGTGAAGAAGGCAGAGAGGACCAGGGTCATCAGG
CCACCCCTGCTCGTGGACAAGATTGTGTGCCGGGAGCTACGGGACCCTGGGTCCTTCCTCCTTATCTACCTGAATGAGTTTCACAGTGCT
GTAGGGGCCTACACGTTCCAGGCCAGTGGCCAGGCCTTGTGCCGTGGCTGGGTGGACACCATTTACAATGCCCAGAACCAGCTGCAACAG
CTGCGTGCACAGGAGCCCCCAGGCAGTCAGCAGCCCCTGCAGAGCCTGGAAGAGGAGGAGGATGAGCAGGAGGAGGAAGAGGAGGAGGAG
GAGGAGGAGGAGGAAGGCGAGGACAGTGGCACTTCAGCTGCCAGCTCCCCTACCATCATGCGGAAAAGCAGCGGCAGCCCCGACTCTCAG
CACTGTGCCTCAGATGGCTCCACGGAGACCCTGGCCATGGTTGTGGTAGAGCCTGGGGACACGCTGTCCTCCCCCGAGTTCGACAGCGGT
CCTTTCAGCTCCCAGTCTGATGAGACCTCTCTCAGCACCACTGCCTCATCTGCCACGCCCACCAGTGAGCTGCTGCCCCTGGGTCCGGTG
GACGGCCGCTCCTGCTCCATGGACTCTGCCTACGGCACCCTCTCCCCAACCTCCTTACAAGACTTTGTGGCCCCAGGCCCAATGGCAGAG
CTAGTGCCTCGGGCCCCAGAGTCCCCACGAGTTCCTTCCCCTCCACCCTCGCCCCGTCTCCGCCGCCGCACCCCTGTCCAGCTGTTGAGC
TGCCCGCCCCACCTGCTCAAGTCTAAGTCCGAGGCCAGCCTCCTCCAGCTGCTGGCAGGGGCTGGCACCCATGGGACACCCTCTGCCCCC
AGCCGCAGCCTGTCAGAGCTCTGCCTGGCTGTTCCAGCCCCAGGTATTAGGACTCAGGGCTCCCCTCAGGAAGCTGGGCCCAGCTGGGAT
TGCCGAGGGGCCCCTAGCCCTGGCAGCGGTCCTGGGCTAGTCGGCTGCCTGGCCGGGGAACCTGCAGGCTCCCACAGGAAGAGGTGTGGA
GACCTGCCCTCGGGGGCCTCTCCCAGGGTCCAGCCTGAGCCCCCACCAGGGGTCTCTGCCCAGCACAGGAAGCTGACCCTGGCCCAGCTC
TACCGAATCAGGACCACCCTGCTGCTTAACTCCACGCTCACTGCCTCGGAGGTCTGAGCAGAGGGAGGCCCCCAAGAGTGCCATTGACCA
AGAGACAGCAGACAGCCTGCCTCCTGGGGCGTGCCGGCACCTGCTTCAGCTACTGCCTCCTGTATGCATGAGCCGGATGCTGGGCAGGAT
CCCTGCCTACGCCCGGGCCCGATTTGCGCTTTGCCGGACTGGATGGAGTGGAGGAGGCCCAGGCCACAGTACCACCCCACCTGCCCAGGC
AGCCCCTCGTCACCTACTCCCCGAAGTTACCAGCTCAGCTCGAGTCTTCAGGGCTGGGCTCCTAGGCTGCCCATCCTACTTCTACCCTCA
CTGGCCTCCAGTGGGATTCACTCCTGCCCTGCCCCCACCTTCCCAGTCCCACAGGCCACCCCTGGCTTGGGCTGGGTTCTGTGAAGTTAC
GTATTTATTGAGCTTTTGGTTCTTTTATAAAGACTTGTCTAGACTCCACTGGGAAGAGTCCTTTGCTTTGGGGCCCAGTGACTCGGGGCA
CTTGAGTTCAGGGCGGCCTCCTTGTGTTCCTGTGCTCCTCCACTTGCCACGGATGGGCCACGGATGGAGCTTGCCATGGGAAGCACTGGG
AAGTAATGGGGTGTGGGGTGCCACCAGACCAACACCCCCAGACTTCCCCACCTTCAGCCACCATCAGAGCCTCTCCCCAGGTGCCCCCCG
GGGATTCAGGGCTGAATCTGCCCAGTTCCCACACTCAGGCCAGCCCTCTTGGGAAGGTGGGTCCTCCATGGGGGTCCCTTCAGGAACTTT
TTTTTTTTTTTTAATACAGAGTCTCACTCTGTCACCTAGGTTGGAGTGCAGTGGTGTGATGTCGGCTCACTGCAACCTCTGCCTCCCGGG
TTCAAACGATTCTCCTGCCCCAGCCACTCTAGTAGCTGGAACTGCAGGTGTGCACCACCACGCCGGGCTAGTTTTTGTATTTTAAGTAGA
GACGGCATTTCACCATATTGGTCAGGCTGGTCTCGAACTCCTGACCCCAAGTGTTCCGCCCGCCTCTGCCTCCCATAGTGCTAGAATTAC
AGGCCTGAGCTACTGCGCTTGGCCCCTTGCGGTACTTTTGGCCCAACCTCCTCCATGGCTGGGGACGCGGAGGCCGAGAGAGAAGTCACT
TGCCCTGGCTCTACCTTGAAGTGGTTCTCAGGGTTGGGGCGAGAGTCGGGGTGGGGACCGAGATGCAGCTCTATCCTGTGCCCCTGGTCG
CAGCAGGCAGCCCAGCGCTTCGCGTGTTCTACTTGGCCTGTCCGCTGCCGCCTAATGAGCTCAGGTCTAGGCCGAGCAGAGGGGGCACCT
GGTCGGACTCGGTTGGGCTCGGGCGGCCCCGCCTCCCCCCGCCCGCCAGGCGGGCCCTTCTCGACGGCGCGGGGCGGGCCCTGCGGGCGC

>96333_96333_7_UBE4B-PLEKHG5_UBE4B_chr1_10093752_ENST00000343090_PLEKHG5_chr1_6537718_ENST00000377748_length(amino acids)=1043AA_BP=3
MEELSADEVCHHADCQQLHRRGPLNLCEACDSKFHSTMHYDGHVRFDLPPQGSVLARNVSTRSCPPRTSPAVDLEEEEEESSVDGKGDRK
STGLKLSKKKARRRHTDDPSKECFTLKFDLNVDIETEIVPAMKKKSLGEVLLPVFERKGIALGKVDIYLDQSNTPLSLTFEAYRFGGHYL
RVKAPAKPGDEGKVEQGMKDSKSLSLPILRPAGTGPPALERVDAQSRRESLDILAPGRRRKNMSEFLGEASIPGQEPPTPSSCSLPSGSS
GSTNTGDSWKNRAASRFSGFFSSGPSTSAFGREVDKMEQLEGKLHTYSLFGLPRLPRGLRFDHDSWEEEYDEDEDEDNACLRLEDSWREL
IDGHEKLTRRQCHQQEAVWELLHTEASYIRKLRVIINLFLCCLLNLQESGLLCEVEAERLFSNIPEIAQLHRRLWASVMAPVLEKARRTR
ALLQPGDFLKGFKMFGSLFKPYIRYCMEEEGCMEYMRGLLRDNDLFRAYITWAEKHPQCQRLKLSDMLAKPHQRLTKYPLLLKSVLRKTE
EPRAKEAVVAMIGSVERFIHHVNACMRQRQERQRLAAVVSRIDAYEVVESSSDEVDKLLKEFLHLDLTAPIPGASPEETRQLLLEGSLRM
KEGKDSKMDVYCFLFTDLLLVTKAVKKAERTRVIRPPLLVDKIVCRELRDPGSFLLIYLNEFHSAVGAYTFQASGQALCRGWVDTIYNAQ
NQLQQLRAQEPPGSQQPLQSLEEEEDEQEEEEEEEEEEEEGEDSGTSAASSPTIMRKSSGSPDSQHCASDGSTETLAMVVVEPGDTLSSP
EFDSGPFSSQSDETSLSTTASSATPTSELLPLGPVDGRSCSMDSAYGTLSPTSLQDFVAPGPMAELVPRAPESPRVPSPPPSPRLRRRTP
VQLLSCPPHLLKSKSEASLLQLLAGAGTHGTPSAPSRSLSELCLAVPAPGIRTQGSPQEAGPSWDCRGAPSPGSGPGLVGCLAGEPAGSH

--------------------------------------------------------------
>96333_96333_8_UBE4B-PLEKHG5_UBE4B_chr1_10093752_ENST00000343090_PLEKHG5_chr1_6537718_ENST00000400915_length(transcript)=3648nt_BP=99nt
CTCTCCTTCCTCCCGCCGTGGTCTCGAGAACAGAAGGATCTCTCCTTAACGCCTTTCACCATTAAGAGGAAAGCGATGGAGGAGCTGAGC
GCTGATGAGGTATGTCACCACGCCGACTGCCAGCAGCTGCACCGCCGGGGGCCCCTCAACCTCTGCGAGGCCTGTGACAGCAAGTTCCAC
AGCACCATGCATTATGATGGGCATGTCCGCTTCGACCTTCCCCCACAAGGCTCTGTGCTGGCCCGGAACGTGTCCACCCGGTCATGCCCG
CCGCGCACCAGCCCCGCAGTGGACTTGGAGGAGGAGGAGGAGGAGAGCTCTGTGGATGGCAAAGGGGACCGGAAGAGCACAGGCCTGAAA
CTCTCCAAGAAGAAAGCAAGGAGGAGACACACGGATGACCCAAGCAAGGAATGCTTCACTCTGAAATTTGACCTGAATGTGGACATTGAG
ACAGAGATCGTCCCAGCCATGAAGAAGAAGTCACTGGGGGAGGTGCTGCTGCCTGTATTTGAAAGGAAGGGCATTGCGCTGGGCAAAGTG
GACATCTACCTGGACCAGTCCAACACACCCCTGTCCCTCACCTTCGAGGCCTACAGGTTCGGGGGACACTACCTTCGTGTCAAAGCCCCA
GCCAAGCCTGGAGATGAGGGCAAGGTGGAGCAGGGCATGAAGGACTCCAAGTCCCTGAGTTTGCCGATTCTGCGGCCAGCTGGGACCGGG
CCCCCCGCCCTGGAGCGTGTGGACGCCCAGAGCCGCCGGGAGAGCCTGGACATCTTGGCCCCTGGCCGCCGCCGCAAGAACATGTCGGAG
TTCCTGGGGGAGGCGAGCATCCCCGGGCAGGAGCCCCCCACGCCCTCCAGCTGCTCTCTGCCCAGCGGCAGCAGTGGCAGCACCAACACT
GGCGACAGCTGGAAGAACCGGGCGGCCAGTCGCTTCAGCGGCTTTTTCAGCTCCGGCCCCAGCACCAGCGCCTTTGGCCGGGAGGTAGAC
AAGATGGAGCAGCTGGAGGGCAAGCTGCACACCTACAGCCTCTTCGGGCTGCCCAGGCTGCCCCGGGGGCTGCGCTTCGACCATGACTCC
TGGGAGGAGGAGTACGATGAAGACGAGGATGAGGACAATGCCTGCCTGAGGCTGGAGGACAGCTGGCGGGAGCTCATTGATGGGCATGAG
AAGCTGACCCGGCGGCAGTGCCACCAGCAGGAGGCGGTGTGGGAGCTGCTGCACACGGAGGCCTCCTACATCAGGAAACTGCGGGTGATC
ATCAACCTGTTCCTGTGCTGCCTCCTGAACCTGCAAGAGTCAGGGCTGCTGTGTGAGGTGGAGGCGGAGCGCCTGTTCAGCAACATCCCG
GAGATCGCGCAGCTGCACCGCAGGCTGTGGGCTAGCGTGATGGCGCCGGTGCTGGAGAAGGCGCGGCGCACGCGAGCGCTGCTACAGCCC
GGGGACTTCCTCAAAGGCTTCAAGATGTTCGGCTCGCTCTTCAAGCCCTACATCCGCTACTGCATGGAGGAGGAGGGCTGCATGGAGTAC
ATGCGCGGCCTGCTGCGCGACAACGACCTCTTCCGGGCCTACATCACGTGGGCGGAGAAGCACCCACAGTGCCAGAGGCTGAAGCTGAGC
GACATGCTGGCCAAACCCCACCAGCGGCTCACCAAGTACCCGCTGCTGCTCAAGTCGGTGCTGAGGAAGACCGAGGAGCCGCGCGCCAAG
GAGGCCGTCGTCGCCATGATCGGCTCCGTGGAGCGCTTCATCCACCACGTGAACGCGTGCATGCGGCAGCGGCAGGAGCGGCAGCGGCTG
GCGGCCGTGGTGAGCCGCATCGACGCCTACGAGGTGGTGGAAAGCAGCAGCGACGAAGTGGACAAGCTCCTGAAGGAATTTCTGCACCTG
GACTTGACAGCGCCCATCCCTGGCGCCTCCCCGGAGGAGACGCGGCAGCTGCTGCTGGAGGGGAGCCTGAGGATGAAGGAGGGGAAGGAC
AGCAAGATGGATGTGTACTGCTTCCTCTTCACGGATCTGCTGTTGGTGACCAAAGCAGTGAAGAAGGCAGAGAGGACCAGGGTCATCAGG
CCACCCCTGCTCGTGGACAAGATTGTGTGCCGGGAGCTACGGGACCCTGGGTCCTTCCTCCTTATCTACCTGAATGAGTTTCACAGTGCT
GTAGGGGCCTACACGTTCCAGGCCAGTGGCCAGGCCTTGTGCCGTGGCTGGGTGGACACCATTTACAATGCCCAGAACCAGCTGCAACAG
CTGCGTGCACAGGAGCCCCCAGGCAGTCAGCAGCCCCTGCAGAGCCTGGAAGAGGAGGAGGATGAGCAGGAGGAGGAAGAGGAGGAGGAG
GAGGAGGAGGAGGAAGGCGAGGACAGTGGCACTTCAGCTGCCAGCTCCCCTACCATCATGCGGAAAAGCAGCGGCAGCCCCGACTCTCAG
CACTGTGCCTCAGATGGCTCCACGGAGACCCTGGCCATGGTTGTGGTAGAGCCTGGGGACACGCTGTCCTCCCCCGAGTTCGACAGCGGT
CCTTTCAGCTCCCAGTCTGATGAGACCTCTCTCAGCACCACTGCCTCATCTGCCACGCCCACCAGTGAGCTGCTGCCCCTGGGTCCGGTG
GACGGCCGCTCCTGCTCCATGGACTCTGCCTACGGCACCCTCTCCCCAACCTCCTTACAAGACTTTGTGGCCCCAGGCCCAATGGCAGAG
CTAGTGCCTCGGGCCCCAGAGTCCCCACGAGTTCCTTCCCCTCCACCCTCGCCCCGTCTCCGCCGCCGCACCCCTGTCCAGCTGTTGAGC
TGCCCGCCCCACCTGCTCAAGTCTAAGTCCGAGGCCAGCCTCCTCCAGCTGCTGGCAGGGGCTGGCACCCATGGGACACCCTCTGCCCCC
AGCCGCAGCCTGTCAGAGCTCTGCCTGGCTGTTCCAGCCCCAGGTATTAGGACTCAGGGCTCCCCTCAGGAAGCTGGGCCCAGCTGGGAT
TGCCGAGGGGCCCCTAGCCCTGGCAGCGGTCCTGGGCTAGTCGGCTGCCTGGCCGGGGAACCTGCAGGCTCCCACAGGAAGAGGTGTGGA
GACCTGCCCTCGGGGGCCTCTCCCAGGGTCCAGCCTGAGCCCCCACCAGGGGTCTCTGCCCAGCACAGGAAGCTGACCCTGGCCCAGCTC
TACCGAATCAGGACCACCCTGCTGCTTAACTCCACGCTCACTGCCTCGGAGGTCTGAGCAGAGGGAGGCCCCCAAGAGTGCCATTGACCA
AGAGACAGCAGACAGCCTGCCTCCTGGGGCGTGCCGGCACCTGCTTCAGCTACTGCCTCCTGTATGCATGAGCCGGATGCTGGGCAGGAT
CCCTGCCTACGCCCGGGCCCGATTTGCGCTTTGCCGGACTGGATGGAGTGGAGGAGGCCCAGGCCACAGTACCACCCCACCTGCCCAGGC
AGCCCCTCGTCACCTACTCCCCGAAGTTACCAGCTCAGCTCGAGTCTTCAGGGCTGGGCTCCTAGGCTGCCCATCCTACTTCTACCCTCA
CTGGCCTCCAGTGGGATTCACTCCTGCCCTGCCCCCACCTTCCCAGTCCCACAGGCCACCCCTGGCTTGGGCTGGGTTCTGTGAAGTTAC

>96333_96333_8_UBE4B-PLEKHG5_UBE4B_chr1_10093752_ENST00000343090_PLEKHG5_chr1_6537718_ENST00000400915_length(amino acids)=1043AA_BP=3
MEELSADEVCHHADCQQLHRRGPLNLCEACDSKFHSTMHYDGHVRFDLPPQGSVLARNVSTRSCPPRTSPAVDLEEEEEESSVDGKGDRK
STGLKLSKKKARRRHTDDPSKECFTLKFDLNVDIETEIVPAMKKKSLGEVLLPVFERKGIALGKVDIYLDQSNTPLSLTFEAYRFGGHYL
RVKAPAKPGDEGKVEQGMKDSKSLSLPILRPAGTGPPALERVDAQSRRESLDILAPGRRRKNMSEFLGEASIPGQEPPTPSSCSLPSGSS
GSTNTGDSWKNRAASRFSGFFSSGPSTSAFGREVDKMEQLEGKLHTYSLFGLPRLPRGLRFDHDSWEEEYDEDEDEDNACLRLEDSWREL
IDGHEKLTRRQCHQQEAVWELLHTEASYIRKLRVIINLFLCCLLNLQESGLLCEVEAERLFSNIPEIAQLHRRLWASVMAPVLEKARRTR
ALLQPGDFLKGFKMFGSLFKPYIRYCMEEEGCMEYMRGLLRDNDLFRAYITWAEKHPQCQRLKLSDMLAKPHQRLTKYPLLLKSVLRKTE
EPRAKEAVVAMIGSVERFIHHVNACMRQRQERQRLAAVVSRIDAYEVVESSSDEVDKLLKEFLHLDLTAPIPGASPEETRQLLLEGSLRM
KEGKDSKMDVYCFLFTDLLLVTKAVKKAERTRVIRPPLLVDKIVCRELRDPGSFLLIYLNEFHSAVGAYTFQASGQALCRGWVDTIYNAQ
NQLQQLRAQEPPGSQQPLQSLEEEEDEQEEEEEEEEEEEEGEDSGTSAASSPTIMRKSSGSPDSQHCASDGSTETLAMVVVEPGDTLSSP
EFDSGPFSSQSDETSLSTTASSATPTSELLPLGPVDGRSCSMDSAYGTLSPTSLQDFVAPGPMAELVPRAPESPRVPSPPPSPRLRRRTP
VQLLSCPPHLLKSKSEASLLQLLAGAGTHGTPSAPSRSLSELCLAVPAPGIRTQGSPQEAGPSWDCRGAPSPGSGPGLVGCLAGEPAGSH

--------------------------------------------------------------
>96333_96333_9_UBE4B-PLEKHG5_UBE4B_chr1_10093752_ENST00000377153_PLEKHG5_chr1_6537718_ENST00000377732_length(transcript)=3970nt_BP=421nt
TAGGAACGCAGCTACCGCGCCACTATCACGAAGAAACAGCAGGCTCGGGGCACGAGACGAACTGGAGACCGCGCTGCCTAGCTGGGTAAC
CTGGGAAGCAGAGGGTAATAAGTGGCGCCTTAAGACAACCCTGTAGCAGCAGCAGTGGCGGCCAAAGGAGGCTGCTCAGGGAACAAGCGG
CTGTAGTAGTCTGTGGGGCGACTGGAGTGACCGAAGCCAAGGCAGTTTAGTGCCTCTCGTGTTCTTATTTTTTAACCTCTGACTATGCAA
TTCTGAAACCTCCCCCATTCGGGGGACCAGACAGCCTGATAGACACCTTCCACTCTCCTTCCTCCCGCCGTGGTCTCGAGAACAGAAGGA
TCTCTCCTTAACGCCTTTCACCATTAAGAGGAAAGCGATGGAGGAGCTGAGCGCTGATGAGGTATGTCACCACGCCGACTGCCAGCAGCT
GCACCGCCGGGGGCCCCTCAACCTCTGCGAGGCCTGTGACAGCAAGTTCCACAGCACCATGCATTATGATGGGCATGTCCGCTTCGACCT
TCCCCCACAAGGCTCTGTGCTGGCCCGGAACGTGTCCACCCGGTCATGCCCGCCGCGCACCAGCCCCGCAGTGGACTTGGAGGAGGAGGA
GGAGGAGAGCTCTGTGGATGGCAAAGGGGACCGGAAGAGCACAGGCCTGAAACTCTCCAAGAAGAAAGCAAGGAGGAGACACACGGATGA
CCCAAGCAAGGAATGCTTCACTCTGAAATTTGACCTGAATGTGGACATTGAGACAGAGATCGTCCCAGCCATGAAGAAGAAGTCACTGGG
GGAGGTGCTGCTGCCTGTATTTGAAAGGAAGGGCATTGCGCTGGGCAAAGTGGACATCTACCTGGACCAGTCCAACACACCCCTGTCCCT
CACCTTCGAGGCCTACAGGTTCGGGGGACACTACCTTCGTGTCAAAGCCCCAGCCAAGCCTGGAGATGAGGGCAAGGTGGAGCAGGGCAT
GAAGGACTCCAAGTCCCTGAGTTTGCCGATTCTGCGGCCAGCTGGGACCGGGCCCCCCGCCCTGGAGCGTGTGGACGCCCAGAGCCGCCG
GGAGAGCCTGGACATCTTGGCCCCTGGCCGCCGCCGCAAGAACATGTCGGAGTTCCTGGGGGAGGCGAGCATCCCCGGGCAGGAGCCCCC
CACGCCCTCCAGCTGCTCTCTGCCCAGCGGCAGCAGTGGCAGCACCAACACTGGCGACAGCTGGAAGAACCGGGCGGCCAGTCGCTTCAG
CGGCTTTTTCAGCTCCGGCCCCAGCACCAGCGCCTTTGGCCGGGAGGTAGACAAGATGGAGCAGCTGGAGGGCAAGCTGCACACCTACAG
CCTCTTCGGGCTGCCCAGGCTGCCCCGGGGGCTGCGCTTCGACCATGACTCCTGGGAGGAGGAGTACGATGAAGACGAGGATGAGGACAA
TGCCTGCCTGAGGCTGGAGGACAGCTGGCGGGAGCTCATTGATGGGCATGAGAAGCTGACCCGGCGGCAGTGCCACCAGCAGGAGGCGGT
GTGGGAGCTGCTGCACACGGAGGCCTCCTACATCAGGAAACTGCGGGTGATCATCAACCTGTTCCTGTGCTGCCTCCTGAACCTGCAAGA
GTCAGGGCTGCTGTGTGAGGTGGAGGCGGAGCGCCTGTTCAGCAACATCCCGGAGATCGCGCAGCTGCACCGCAGGCTGTGGGCTAGCGT
GATGGCGCCGGTGCTGGAGAAGGCGCGGCGCACGCGAGCGCTGCTACAGCCCGGGGACTTCCTCAAAGGCTTCAAGATGTTCGGCTCGCT
CTTCAAGCCCTACATCCGCTACTGCATGGAGGAGGAGGGCTGCATGGAGTACATGCGCGGCCTGCTGCGCGACAACGACCTCTTCCGGGC
CTACATCACGTGGGCGGAGAAGCACCCACAGTGCCAGAGGCTGAAGCTGAGCGACATGCTGGCCAAACCCCACCAGCGGCTCACCAAGTA
CCCGCTGCTGCTCAAGTCGGTGCTGAGGAAGACCGAGGAGCCGCGCGCCAAGGAGGCCGTCGTCGCCATGATCGGCTCCGTGGAGCGCTT
CATCCACCACGTGAACGCGTGCATGCGGCAGCGGCAGGAGCGGCAGCGGCTGGCGGCCGTGGTGAGCCGCATCGACGCCTACGAGGTGGT
GGAAAGCAGCAGCGACGAAGTGGACAAGCTCCTGAAGGAATTTCTGCACCTGGACTTGACAGCGCCCATCCCTGGCGCCTCCCCGGAGGA
GACGCGGCAGCTGCTGCTGGAGGGGAGCCTGAGGATGAAGGAGGGGAAGGACAGCAAGATGGATGTGTACTGCTTCCTCTTCACGGATCT
GCTGTTGGTGACCAAAGCAGTGAAGAAGGCAGAGAGGACCAGGGTCATCAGGCCACCCCTGCTCGTGGACAAGATTGTGTGCCGGGAGCT
ACGGGACCCTGGGTCCTTCCTCCTTATCTACCTGAATGAGTTTCACAGTGCTGTAGGGGCCTACACGTTCCAGGCCAGTGGCCAGGCCTT
GTGCCGTGGCTGGGTGGACACCATTTACAATGCCCAGAACCAGCTGCAACAGCTGCGTGCACAGGAGCCCCCAGGCAGTCAGCAGCCCCT
GCAGAGCCTGGAAGAGGAGGAGGATGAGCAGGAGGAGGAAGAGGAGGAGGAGGAGGAGGAGGAGGAAGGCGAGGACAGTGGCACTTCAGC
TGCCAGCTCCCCTACCATCATGCGGAAAAGCAGCGGCAGCCCCGACTCTCAGCACTGTGCCTCAGATGGCTCCACGGAGACCCTGGCCAT
GGTTGTGGTAGAGCCTGGGGACACGCTGTCCTCCCCCGAGTTCGACAGCGGTCCTTTCAGCTCCCAGTCTGATGAGACCTCTCTCAGCAC
CACTGCCTCATCTGCCACGCCCACCAGTGAGCTGCTGCCCCTGGGTCCGGTGGACGGCCGCTCCTGCTCCATGGACTCTGCCTACGGCAC
CCTCTCCCCAACCTCCTTACAAGACTTTGTGGCCCCAGGCCCAATGGCAGAGCTAGTGCCTCGGGCCCCAGAGTCCCCACGAGTTCCTTC
CCCTCCACCCTCGCCCCGTCTCCGCCGCCGCACCCCTGTCCAGCTGTTGAGCTGCCCGCCCCACCTGCTCAAGTCTAAGTCCGAGGCCAG
CCTCCTCCAGCTGCTGGCAGGGGCTGGCACCCATGGGACACCCTCTGCCCCCAGCCGCAGCCTGTCAGAGCTCTGCCTGGCTGTTCCAGC
CCCAGGTATTAGGACTCAGGGCTCCCCTCAGGAAGCTGGGCCCAGCTGGGATTGCCGAGGGGCCCCTAGCCCTGGCAGCGGTCCTGGGCT
AGTCGGCTGCCTGGCCGGGGAACCTGCAGGCTCCCACAGGAAGAGGTGTGGAGACCTGCCCTCGGGGGCCTCTCCCAGGGTCCAGCCTGA
GCCCCCACCAGGGGTCTCTGCCCAGCACAGGAAGCTGACCCTGGCCCAGCTCTACCGAATCAGGACCACCCTGCTGCTTAACTCCACGCT
CACTGCCTCGGAGGTCTGAGCAGAGGGAGGCCCCCAAGAGTGCCATTGACCAAGAGACAGCAGACAGCCTGCCTCCTGGGGCGTGCCGGC
ACCTGCTTCAGCTACTGCCTCCTGTATGCATGAGCCGGATGCTGGGCAGGATCCCTGCCTACGCCCGGGCCCGATTTGCGCTTTGCCGGA
CTGGATGGAGTGGAGGAGGCCCAGGCCACAGTACCACCCCACCTGCCCAGGCAGCCCCTCGTCACCTACTCCCCGAAGTTACCAGCTCAG
CTCGAGTCTTCAGGGCTGGGCTCCTAGGCTGCCCATCCTACTTCTACCCTCACTGGCCTCCAGTGGGATTCACTCCTGCCCTGCCCCCAC
CTTCCCAGTCCCACAGGCCACCCCTGGCTTGGGCTGGGTTCTGTGAAGTTACGTATTTATTGAGCTTTTGGTTCTTTTATAAAGACTTGT

>96333_96333_9_UBE4B-PLEKHG5_UBE4B_chr1_10093752_ENST00000377153_PLEKHG5_chr1_6537718_ENST00000377732_length(amino acids)=1043AA_BP=3
MEELSADEVCHHADCQQLHRRGPLNLCEACDSKFHSTMHYDGHVRFDLPPQGSVLARNVSTRSCPPRTSPAVDLEEEEEESSVDGKGDRK
STGLKLSKKKARRRHTDDPSKECFTLKFDLNVDIETEIVPAMKKKSLGEVLLPVFERKGIALGKVDIYLDQSNTPLSLTFEAYRFGGHYL
RVKAPAKPGDEGKVEQGMKDSKSLSLPILRPAGTGPPALERVDAQSRRESLDILAPGRRRKNMSEFLGEASIPGQEPPTPSSCSLPSGSS
GSTNTGDSWKNRAASRFSGFFSSGPSTSAFGREVDKMEQLEGKLHTYSLFGLPRLPRGLRFDHDSWEEEYDEDEDEDNACLRLEDSWREL
IDGHEKLTRRQCHQQEAVWELLHTEASYIRKLRVIINLFLCCLLNLQESGLLCEVEAERLFSNIPEIAQLHRRLWASVMAPVLEKARRTR
ALLQPGDFLKGFKMFGSLFKPYIRYCMEEEGCMEYMRGLLRDNDLFRAYITWAEKHPQCQRLKLSDMLAKPHQRLTKYPLLLKSVLRKTE
EPRAKEAVVAMIGSVERFIHHVNACMRQRQERQRLAAVVSRIDAYEVVESSSDEVDKLLKEFLHLDLTAPIPGASPEETRQLLLEGSLRM
KEGKDSKMDVYCFLFTDLLLVTKAVKKAERTRVIRPPLLVDKIVCRELRDPGSFLLIYLNEFHSAVGAYTFQASGQALCRGWVDTIYNAQ
NQLQQLRAQEPPGSQQPLQSLEEEEDEQEEEEEEEEEEEEGEDSGTSAASSPTIMRKSSGSPDSQHCASDGSTETLAMVVVEPGDTLSSP
EFDSGPFSSQSDETSLSTTASSATPTSELLPLGPVDGRSCSMDSAYGTLSPTSLQDFVAPGPMAELVPRAPESPRVPSPPPSPRLRRRTP
VQLLSCPPHLLKSKSEASLLQLLAGAGTHGTPSAPSRSLSELCLAVPAPGIRTQGSPQEAGPSWDCRGAPSPGSGPGLVGCLAGEPAGSH

--------------------------------------------------------------
>96333_96333_10_UBE4B-PLEKHG5_UBE4B_chr1_10093752_ENST00000377153_PLEKHG5_chr1_6537718_ENST00000377740_length(transcript)=3277nt_BP=421nt
TAGGAACGCAGCTACCGCGCCACTATCACGAAGAAACAGCAGGCTCGGGGCACGAGACGAACTGGAGACCGCGCTGCCTAGCTGGGTAAC
CTGGGAAGCAGAGGGTAATAAGTGGCGCCTTAAGACAACCCTGTAGCAGCAGCAGTGGCGGCCAAAGGAGGCTGCTCAGGGAACAAGCGG
CTGTAGTAGTCTGTGGGGCGACTGGAGTGACCGAAGCCAAGGCAGTTTAGTGCCTCTCGTGTTCTTATTTTTTAACCTCTGACTATGCAA
TTCTGAAACCTCCCCCATTCGGGGGACCAGACAGCCTGATAGACACCTTCCACTCTCCTTCCTCCCGCCGTGGTCTCGAGAACAGAAGGA
TCTCTCCTTAACGCCTTTCACCATTAAGAGGAAAGCGATGGAGGAGCTGAGCGCTGATGAGGTATGTCACCACGCCGACTGCCAGCAGCT
GCACCGCCGGGGGCCCCTCAACCTCTGCGAGGCCTGTGACAGCAAGTTCCACAGCACCATGCATTATGATGGGCATGTCCGCTTCGACCT
TCCCCCACAAGGCTCTGTGCTGGCCCGGAACGTGTCCACCCGGTCATGCCCGCCGCGCACCAGCCCCGCAGTGGACTTGGAGGAGGAGGA
GGAGGAGAGCTCTGTGGATGGCAAAGGGGACCGGAAGAGCACAGGCCTGAAACTCTCCAAGAAGAAAGCAAGGAGGAGACACACGGATGA
CCCAAGCAAGGAATGCTTCACTCTGAAATTTGACCTGAATGTGGACATTGAGACAGAGATCGTCCCAGCCATGAAGAAGAAGTCACTGGG
GGAGGTGCTGCTGCCTGTATTTGAAAGGAAGGGCATTGCGCTGGGCAAAGTGGACATCTACCTGGACCAGTCCAACACACCCCTGTCCCT
CACCTTCGAGGCCTACAGGTTCGGGGGACACTACCTTCGTGTCAAAGCCCCAGCCAAGCCTGGAGATGAGGGCAAGGTGGAGCAGGGCAT
GAAGGACTCCAAGTCCCTGAGTTTGCCGATTCTGCGGCCAGCTGGGACCGGGCCCCCCGCCCTGGAGCGTGTGGACGCCCAGAGCCGCCG
GGAGAGCCTGGACATCTTGGCCCCTGGCCGCCGCCGCAAGAACATGTCGGAGTTCCTGGGGGAGGCGAGCATCCCCGGGCAGGAGCCCCC
CACGCCCTCCAGCTGCTCTCTGCCCAGCGGCAGCAGTGGCAGCACCAACACTGGCGACAGCTGGAAGAACCGGGCGGCCAGTCGCTTCAG
CGGCTTTTTCAGCTCCGGCCCCAGCACCAGCGCCTTTGGCCGGGAGGTAGACAAGATGGAGCAGCTGGAGGGCAAGCTGCACACCTACAG
CCTCTTCGGGCTGCCCAGGCTGCCCCGGGGGCTGCGCTTCGACCATGACTCCTGGGAGGAGGAGTACGATGAAGACGAGGATGAGGACAA
TGCCTGCCTGAGGCTGGAGGACAGCTGGCGGGAGCTCATTGATGGGCATGAGAAGCTGACCCGGCGGCAGTGCCACCAGCAGGAGGCGGT
GTGGGAGCTGCTGCACACGGAGGCCTCCTACATCAGGAAACTGCGGGTGATCATCAACCTGTTCCTGTGCTGCCTCCTGAACCTGCAAGA
GTCAGGGCTGCTGTGTGAGGTGGAGGCGGAGCGCCTGTTCAGCAACATCCCGGAGATCGCGCAGCTGCACCGCAGGCTGTGGGCTAGCGT
GATGGCGCCGGTGCTGGAGAAGGCGCGGCGCACGCGAGCGCTGCTACAGCCCGGGGACTTCCTCAAAGGCTTCAAGATGTTCGGCTCGCT
CTTCAAGCCCTACATCCGCTACTGCATGGAGGAGGAGGGCTGCATGGAGTACATGCGCGGCCTGCTGCGCGACAACGACCTCTTCCGGGC
CTACATCACGTGGGCGGAGAAGCACCCACAGTGCCAGAGGCTGAAGCTGAGCGACATGCTGGCCAAACCCCACCAGCGGCTCACCAAGTA
CCCGCTGCTGCTCAAGTCGGTGCTGAGGAAGACCGAGGAGCCGCGCGCCAAGGAGGCCGTCGTCGCCATGATCGGCTCCGTGGAGCGCTT
CATCCACCACGTGAACGCGTGCATGCGGCAGCGGCAGGAGCGGCAGCGGCTGGCGGCCGTGGTGAGCCGCATCGACGCCTACGAGGTGGT
GGAAAGCAGCAGCGACGAAGTGGACAAGCTCCTGAAGGAATTTCTGCACCTGGACTTGACAGCGCCCATCCCTGGCGCCTCCCCGGAGGA
GACGCGGCAGCTGCTGCTGGAGGGGAGCCTGAGGATGAAGGAGGGGAAGGACAGCAAGATGGATGTGTACTGCTTCCTCTTCACGGATCT
GCTGTTGGTGACCAAAGCAGTGAAGAAGGCAGAGAGGACCAGGGTCATCAGGCCACCCCTGCTCGTGGACAAGATTGTGTGCCGGGAGCT
ACGGGACCCTGGGTCCTTCCTCCTTATCTACCTGAATGAGTTTCACAGTGCTGTAGGGGCCTACACGTTCCAGGCCAGTGGCCAGGCCTT
GTGCCGTGGCTGGGTGGACACCATTTACAATGCCCAGAACCAGCTGCAACAGCTGCGTGCACAGGAGCCCCCAGGCAGTCAGCAGCCCCT
GCAGAGCCTGGAAGAGGAGGAGGATGAGCAGGAGGAGGAAGAGGAGGAGGAGGAGGAGGAGGAGGAAGGCGAGGACAGTGGCACTTCAGC
TGCCAGCTCCCCTACCATCATGCGGAAAAGCAGCGGCAGCCCCGACTCTCAGCACTGGAAGCTGACCCTGGCCCAGCTCTACCGAATCAG
GACCACCCTGCTGCTTAACTCCACGCTCACTGCCTCGGAGGTCTGAGCAGAGGGAGGCCCCCAAGAGTGCCATTGACCAAGAGACAGCAG
ACAGCCTGCCTCCTGGGGCGTGCCGGCACCTGCTTCAGCTACTGCCTCCTGTATGCATGAGCCGGATGCTGGGCAGGATCCCTGCCTACG
CCCGGGCCCGATTTGCGCTTTGCCGGACTGGATGGAGTGGAGGAGGCCCAGGCCACAGTACCACCCCACCTGCCCAGGCAGCCCCTCGTC
ACCTACTCCCCGAAGTTACCAGCTCAGCTCGAGTCTTCAGGGCTGGGCTCCTAGGCTGCCCATCCTACTTCTACCCTCACTGGCCTCCAG
TGGGATTCACTCCTGCCCTGCCCCCACCTTCCCAGTCCCACAGGCCACCCCTGGCTTGGGCTGGGTTCTGTGAAGTTACGTATTTATTGA

>96333_96333_10_UBE4B-PLEKHG5_UBE4B_chr1_10093752_ENST00000377153_PLEKHG5_chr1_6537718_ENST00000377740_length(amino acids)=812AA_BP=3
MEELSADEVCHHADCQQLHRRGPLNLCEACDSKFHSTMHYDGHVRFDLPPQGSVLARNVSTRSCPPRTSPAVDLEEEEEESSVDGKGDRK
STGLKLSKKKARRRHTDDPSKECFTLKFDLNVDIETEIVPAMKKKSLGEVLLPVFERKGIALGKVDIYLDQSNTPLSLTFEAYRFGGHYL
RVKAPAKPGDEGKVEQGMKDSKSLSLPILRPAGTGPPALERVDAQSRRESLDILAPGRRRKNMSEFLGEASIPGQEPPTPSSCSLPSGSS
GSTNTGDSWKNRAASRFSGFFSSGPSTSAFGREVDKMEQLEGKLHTYSLFGLPRLPRGLRFDHDSWEEEYDEDEDEDNACLRLEDSWREL
IDGHEKLTRRQCHQQEAVWELLHTEASYIRKLRVIINLFLCCLLNLQESGLLCEVEAERLFSNIPEIAQLHRRLWASVMAPVLEKARRTR
ALLQPGDFLKGFKMFGSLFKPYIRYCMEEEGCMEYMRGLLRDNDLFRAYITWAEKHPQCQRLKLSDMLAKPHQRLTKYPLLLKSVLRKTE
EPRAKEAVVAMIGSVERFIHHVNACMRQRQERQRLAAVVSRIDAYEVVESSSDEVDKLLKEFLHLDLTAPIPGASPEETRQLLLEGSLRM
KEGKDSKMDVYCFLFTDLLLVTKAVKKAERTRVIRPPLLVDKIVCRELRDPGSFLLIYLNEFHSAVGAYTFQASGQALCRGWVDTIYNAQ
NQLQQLRAQEPPGSQQPLQSLEEEEDEQEEEEEEEEEEEEGEDSGTSAASSPTIMRKSSGSPDSQHWKLTLAQLYRIRTTLLLNSTLTAS

--------------------------------------------------------------
>96333_96333_11_UBE4B-PLEKHG5_UBE4B_chr1_10093752_ENST00000377153_PLEKHG5_chr1_6537718_ENST00000377748_length(transcript)=5000nt_BP=421nt
TAGGAACGCAGCTACCGCGCCACTATCACGAAGAAACAGCAGGCTCGGGGCACGAGACGAACTGGAGACCGCGCTGCCTAGCTGGGTAAC
CTGGGAAGCAGAGGGTAATAAGTGGCGCCTTAAGACAACCCTGTAGCAGCAGCAGTGGCGGCCAAAGGAGGCTGCTCAGGGAACAAGCGG
CTGTAGTAGTCTGTGGGGCGACTGGAGTGACCGAAGCCAAGGCAGTTTAGTGCCTCTCGTGTTCTTATTTTTTAACCTCTGACTATGCAA
TTCTGAAACCTCCCCCATTCGGGGGACCAGACAGCCTGATAGACACCTTCCACTCTCCTTCCTCCCGCCGTGGTCTCGAGAACAGAAGGA
TCTCTCCTTAACGCCTTTCACCATTAAGAGGAAAGCGATGGAGGAGCTGAGCGCTGATGAGGTATGTCACCACGCCGACTGCCAGCAGCT
GCACCGCCGGGGGCCCCTCAACCTCTGCGAGGCCTGTGACAGCAAGTTCCACAGCACCATGCATTATGATGGGCATGTCCGCTTCGACCT
TCCCCCACAAGGCTCTGTGCTGGCCCGGAACGTGTCCACCCGGTCATGCCCGCCGCGCACCAGCCCCGCAGTGGACTTGGAGGAGGAGGA
GGAGGAGAGCTCTGTGGATGGCAAAGGGGACCGGAAGAGCACAGGCCTGAAACTCTCCAAGAAGAAAGCAAGGAGGAGACACACGGATGA
CCCAAGCAAGGAATGCTTCACTCTGAAATTTGACCTGAATGTGGACATTGAGACAGAGATCGTCCCAGCCATGAAGAAGAAGTCACTGGG
GGAGGTGCTGCTGCCTGTATTTGAAAGGAAGGGCATTGCGCTGGGCAAAGTGGACATCTACCTGGACCAGTCCAACACACCCCTGTCCCT
CACCTTCGAGGCCTACAGGTTCGGGGGACACTACCTTCGTGTCAAAGCCCCAGCCAAGCCTGGAGATGAGGGCAAGGTGGAGCAGGGCAT
GAAGGACTCCAAGTCCCTGAGTTTGCCGATTCTGCGGCCAGCTGGGACCGGGCCCCCCGCCCTGGAGCGTGTGGACGCCCAGAGCCGCCG
GGAGAGCCTGGACATCTTGGCCCCTGGCCGCCGCCGCAAGAACATGTCGGAGTTCCTGGGGGAGGCGAGCATCCCCGGGCAGGAGCCCCC
CACGCCCTCCAGCTGCTCTCTGCCCAGCGGCAGCAGTGGCAGCACCAACACTGGCGACAGCTGGAAGAACCGGGCGGCCAGTCGCTTCAG
CGGCTTTTTCAGCTCCGGCCCCAGCACCAGCGCCTTTGGCCGGGAGGTAGACAAGATGGAGCAGCTGGAGGGCAAGCTGCACACCTACAG
CCTCTTCGGGCTGCCCAGGCTGCCCCGGGGGCTGCGCTTCGACCATGACTCCTGGGAGGAGGAGTACGATGAAGACGAGGATGAGGACAA
TGCCTGCCTGAGGCTGGAGGACAGCTGGCGGGAGCTCATTGATGGGCATGAGAAGCTGACCCGGCGGCAGTGCCACCAGCAGGAGGCGGT
GTGGGAGCTGCTGCACACGGAGGCCTCCTACATCAGGAAACTGCGGGTGATCATCAACCTGTTCCTGTGCTGCCTCCTGAACCTGCAAGA
GTCAGGGCTGCTGTGTGAGGTGGAGGCGGAGCGCCTGTTCAGCAACATCCCGGAGATCGCGCAGCTGCACCGCAGGCTGTGGGCTAGCGT
GATGGCGCCGGTGCTGGAGAAGGCGCGGCGCACGCGAGCGCTGCTACAGCCCGGGGACTTCCTCAAAGGCTTCAAGATGTTCGGCTCGCT
CTTCAAGCCCTACATCCGCTACTGCATGGAGGAGGAGGGCTGCATGGAGTACATGCGCGGCCTGCTGCGCGACAACGACCTCTTCCGGGC
CTACATCACGTGGGCGGAGAAGCACCCACAGTGCCAGAGGCTGAAGCTGAGCGACATGCTGGCCAAACCCCACCAGCGGCTCACCAAGTA
CCCGCTGCTGCTCAAGTCGGTGCTGAGGAAGACCGAGGAGCCGCGCGCCAAGGAGGCCGTCGTCGCCATGATCGGCTCCGTGGAGCGCTT
CATCCACCACGTGAACGCGTGCATGCGGCAGCGGCAGGAGCGGCAGCGGCTGGCGGCCGTGGTGAGCCGCATCGACGCCTACGAGGTGGT
GGAAAGCAGCAGCGACGAAGTGGACAAGCTCCTGAAGGAATTTCTGCACCTGGACTTGACAGCGCCCATCCCTGGCGCCTCCCCGGAGGA
GACGCGGCAGCTGCTGCTGGAGGGGAGCCTGAGGATGAAGGAGGGGAAGGACAGCAAGATGGATGTGTACTGCTTCCTCTTCACGGATCT
GCTGTTGGTGACCAAAGCAGTGAAGAAGGCAGAGAGGACCAGGGTCATCAGGCCACCCCTGCTCGTGGACAAGATTGTGTGCCGGGAGCT
ACGGGACCCTGGGTCCTTCCTCCTTATCTACCTGAATGAGTTTCACAGTGCTGTAGGGGCCTACACGTTCCAGGCCAGTGGCCAGGCCTT
GTGCCGTGGCTGGGTGGACACCATTTACAATGCCCAGAACCAGCTGCAACAGCTGCGTGCACAGGAGCCCCCAGGCAGTCAGCAGCCCCT
GCAGAGCCTGGAAGAGGAGGAGGATGAGCAGGAGGAGGAAGAGGAGGAGGAGGAGGAGGAGGAGGAAGGCGAGGACAGTGGCACTTCAGC
TGCCAGCTCCCCTACCATCATGCGGAAAAGCAGCGGCAGCCCCGACTCTCAGCACTGTGCCTCAGATGGCTCCACGGAGACCCTGGCCAT
GGTTGTGGTAGAGCCTGGGGACACGCTGTCCTCCCCCGAGTTCGACAGCGGTCCTTTCAGCTCCCAGTCTGATGAGACCTCTCTCAGCAC
CACTGCCTCATCTGCCACGCCCACCAGTGAGCTGCTGCCCCTGGGTCCGGTGGACGGCCGCTCCTGCTCCATGGACTCTGCCTACGGCAC
CCTCTCCCCAACCTCCTTACAAGACTTTGTGGCCCCAGGCCCAATGGCAGAGCTAGTGCCTCGGGCCCCAGAGTCCCCACGAGTTCCTTC
CCCTCCACCCTCGCCCCGTCTCCGCCGCCGCACCCCTGTCCAGCTGTTGAGCTGCCCGCCCCACCTGCTCAAGTCTAAGTCCGAGGCCAG
CCTCCTCCAGCTGCTGGCAGGGGCTGGCACCCATGGGACACCCTCTGCCCCCAGCCGCAGCCTGTCAGAGCTCTGCCTGGCTGTTCCAGC
CCCAGGTATTAGGACTCAGGGCTCCCCTCAGGAAGCTGGGCCCAGCTGGGATTGCCGAGGGGCCCCTAGCCCTGGCAGCGGTCCTGGGCT
AGTCGGCTGCCTGGCCGGGGAACCTGCAGGCTCCCACAGGAAGAGGTGTGGAGACCTGCCCTCGGGGGCCTCTCCCAGGGTCCAGCCTGA
GCCCCCACCAGGGGTCTCTGCCCAGCACAGGAAGCTGACCCTGGCCCAGCTCTACCGAATCAGGACCACCCTGCTGCTTAACTCCACGCT
CACTGCCTCGGAGGTCTGAGCAGAGGGAGGCCCCCAAGAGTGCCATTGACCAAGAGACAGCAGACAGCCTGCCTCCTGGGGCGTGCCGGC
ACCTGCTTCAGCTACTGCCTCCTGTATGCATGAGCCGGATGCTGGGCAGGATCCCTGCCTACGCCCGGGCCCGATTTGCGCTTTGCCGGA
CTGGATGGAGTGGAGGAGGCCCAGGCCACAGTACCACCCCACCTGCCCAGGCAGCCCCTCGTCACCTACTCCCCGAAGTTACCAGCTCAG
CTCGAGTCTTCAGGGCTGGGCTCCTAGGCTGCCCATCCTACTTCTACCCTCACTGGCCTCCAGTGGGATTCACTCCTGCCCTGCCCCCAC
CTTCCCAGTCCCACAGGCCACCCCTGGCTTGGGCTGGGTTCTGTGAAGTTACGTATTTATTGAGCTTTTGGTTCTTTTATAAAGACTTGT
CTAGACTCCACTGGGAAGAGTCCTTTGCTTTGGGGCCCAGTGACTCGGGGCACTTGAGTTCAGGGCGGCCTCCTTGTGTTCCTGTGCTCC
TCCACTTGCCACGGATGGGCCACGGATGGAGCTTGCCATGGGAAGCACTGGGAAGTAATGGGGTGTGGGGTGCCACCAGACCAACACCCC
CAGACTTCCCCACCTTCAGCCACCATCAGAGCCTCTCCCCAGGTGCCCCCCGGGGATTCAGGGCTGAATCTGCCCAGTTCCCACACTCAG
GCCAGCCCTCTTGGGAAGGTGGGTCCTCCATGGGGGTCCCTTCAGGAACTTTTTTTTTTTTTTTAATACAGAGTCTCACTCTGTCACCTA
GGTTGGAGTGCAGTGGTGTGATGTCGGCTCACTGCAACCTCTGCCTCCCGGGTTCAAACGATTCTCCTGCCCCAGCCACTCTAGTAGCTG
GAACTGCAGGTGTGCACCACCACGCCGGGCTAGTTTTTGTATTTTAAGTAGAGACGGCATTTCACCATATTGGTCAGGCTGGTCTCGAAC
TCCTGACCCCAAGTGTTCCGCCCGCCTCTGCCTCCCATAGTGCTAGAATTACAGGCCTGAGCTACTGCGCTTGGCCCCTTGCGGTACTTT
TGGCCCAACCTCCTCCATGGCTGGGGACGCGGAGGCCGAGAGAGAAGTCACTTGCCCTGGCTCTACCTTGAAGTGGTTCTCAGGGTTGGG
GCGAGAGTCGGGGTGGGGACCGAGATGCAGCTCTATCCTGTGCCCCTGGTCGCAGCAGGCAGCCCAGCGCTTCGCGTGTTCTACTTGGCC
TGTCCGCTGCCGCCTAATGAGCTCAGGTCTAGGCCGAGCAGAGGGGGCACCTGGTCGGACTCGGTTGGGCTCGGGCGGCCCCGCCTCCCC
CCGCCCGCCAGGCGGGCCCTTCTCGACGGCGCGGGGCGGGCCCTGCGGGCGCGGGGCTGAAGGCGGAACCACGACGGGCAGAGAGCACGG

>96333_96333_11_UBE4B-PLEKHG5_UBE4B_chr1_10093752_ENST00000377153_PLEKHG5_chr1_6537718_ENST00000377748_length(amino acids)=1043AA_BP=3
MEELSADEVCHHADCQQLHRRGPLNLCEACDSKFHSTMHYDGHVRFDLPPQGSVLARNVSTRSCPPRTSPAVDLEEEEEESSVDGKGDRK
STGLKLSKKKARRRHTDDPSKECFTLKFDLNVDIETEIVPAMKKKSLGEVLLPVFERKGIALGKVDIYLDQSNTPLSLTFEAYRFGGHYL
RVKAPAKPGDEGKVEQGMKDSKSLSLPILRPAGTGPPALERVDAQSRRESLDILAPGRRRKNMSEFLGEASIPGQEPPTPSSCSLPSGSS
GSTNTGDSWKNRAASRFSGFFSSGPSTSAFGREVDKMEQLEGKLHTYSLFGLPRLPRGLRFDHDSWEEEYDEDEDEDNACLRLEDSWREL
IDGHEKLTRRQCHQQEAVWELLHTEASYIRKLRVIINLFLCCLLNLQESGLLCEVEAERLFSNIPEIAQLHRRLWASVMAPVLEKARRTR
ALLQPGDFLKGFKMFGSLFKPYIRYCMEEEGCMEYMRGLLRDNDLFRAYITWAEKHPQCQRLKLSDMLAKPHQRLTKYPLLLKSVLRKTE
EPRAKEAVVAMIGSVERFIHHVNACMRQRQERQRLAAVVSRIDAYEVVESSSDEVDKLLKEFLHLDLTAPIPGASPEETRQLLLEGSLRM
KEGKDSKMDVYCFLFTDLLLVTKAVKKAERTRVIRPPLLVDKIVCRELRDPGSFLLIYLNEFHSAVGAYTFQASGQALCRGWVDTIYNAQ
NQLQQLRAQEPPGSQQPLQSLEEEEDEQEEEEEEEEEEEEGEDSGTSAASSPTIMRKSSGSPDSQHCASDGSTETLAMVVVEPGDTLSSP
EFDSGPFSSQSDETSLSTTASSATPTSELLPLGPVDGRSCSMDSAYGTLSPTSLQDFVAPGPMAELVPRAPESPRVPSPPPSPRLRRRTP
VQLLSCPPHLLKSKSEASLLQLLAGAGTHGTPSAPSRSLSELCLAVPAPGIRTQGSPQEAGPSWDCRGAPSPGSGPGLVGCLAGEPAGSH

--------------------------------------------------------------
>96333_96333_12_UBE4B-PLEKHG5_UBE4B_chr1_10093752_ENST00000377153_PLEKHG5_chr1_6537718_ENST00000400915_length(transcript)=3970nt_BP=421nt
TAGGAACGCAGCTACCGCGCCACTATCACGAAGAAACAGCAGGCTCGGGGCACGAGACGAACTGGAGACCGCGCTGCCTAGCTGGGTAAC
CTGGGAAGCAGAGGGTAATAAGTGGCGCCTTAAGACAACCCTGTAGCAGCAGCAGTGGCGGCCAAAGGAGGCTGCTCAGGGAACAAGCGG
CTGTAGTAGTCTGTGGGGCGACTGGAGTGACCGAAGCCAAGGCAGTTTAGTGCCTCTCGTGTTCTTATTTTTTAACCTCTGACTATGCAA
TTCTGAAACCTCCCCCATTCGGGGGACCAGACAGCCTGATAGACACCTTCCACTCTCCTTCCTCCCGCCGTGGTCTCGAGAACAGAAGGA
TCTCTCCTTAACGCCTTTCACCATTAAGAGGAAAGCGATGGAGGAGCTGAGCGCTGATGAGGTATGTCACCACGCCGACTGCCAGCAGCT
GCACCGCCGGGGGCCCCTCAACCTCTGCGAGGCCTGTGACAGCAAGTTCCACAGCACCATGCATTATGATGGGCATGTCCGCTTCGACCT
TCCCCCACAAGGCTCTGTGCTGGCCCGGAACGTGTCCACCCGGTCATGCCCGCCGCGCACCAGCCCCGCAGTGGACTTGGAGGAGGAGGA
GGAGGAGAGCTCTGTGGATGGCAAAGGGGACCGGAAGAGCACAGGCCTGAAACTCTCCAAGAAGAAAGCAAGGAGGAGACACACGGATGA
CCCAAGCAAGGAATGCTTCACTCTGAAATTTGACCTGAATGTGGACATTGAGACAGAGATCGTCCCAGCCATGAAGAAGAAGTCACTGGG
GGAGGTGCTGCTGCCTGTATTTGAAAGGAAGGGCATTGCGCTGGGCAAAGTGGACATCTACCTGGACCAGTCCAACACACCCCTGTCCCT
CACCTTCGAGGCCTACAGGTTCGGGGGACACTACCTTCGTGTCAAAGCCCCAGCCAAGCCTGGAGATGAGGGCAAGGTGGAGCAGGGCAT
GAAGGACTCCAAGTCCCTGAGTTTGCCGATTCTGCGGCCAGCTGGGACCGGGCCCCCCGCCCTGGAGCGTGTGGACGCCCAGAGCCGCCG
GGAGAGCCTGGACATCTTGGCCCCTGGCCGCCGCCGCAAGAACATGTCGGAGTTCCTGGGGGAGGCGAGCATCCCCGGGCAGGAGCCCCC
CACGCCCTCCAGCTGCTCTCTGCCCAGCGGCAGCAGTGGCAGCACCAACACTGGCGACAGCTGGAAGAACCGGGCGGCCAGTCGCTTCAG
CGGCTTTTTCAGCTCCGGCCCCAGCACCAGCGCCTTTGGCCGGGAGGTAGACAAGATGGAGCAGCTGGAGGGCAAGCTGCACACCTACAG
CCTCTTCGGGCTGCCCAGGCTGCCCCGGGGGCTGCGCTTCGACCATGACTCCTGGGAGGAGGAGTACGATGAAGACGAGGATGAGGACAA
TGCCTGCCTGAGGCTGGAGGACAGCTGGCGGGAGCTCATTGATGGGCATGAGAAGCTGACCCGGCGGCAGTGCCACCAGCAGGAGGCGGT
GTGGGAGCTGCTGCACACGGAGGCCTCCTACATCAGGAAACTGCGGGTGATCATCAACCTGTTCCTGTGCTGCCTCCTGAACCTGCAAGA
GTCAGGGCTGCTGTGTGAGGTGGAGGCGGAGCGCCTGTTCAGCAACATCCCGGAGATCGCGCAGCTGCACCGCAGGCTGTGGGCTAGCGT
GATGGCGCCGGTGCTGGAGAAGGCGCGGCGCACGCGAGCGCTGCTACAGCCCGGGGACTTCCTCAAAGGCTTCAAGATGTTCGGCTCGCT
CTTCAAGCCCTACATCCGCTACTGCATGGAGGAGGAGGGCTGCATGGAGTACATGCGCGGCCTGCTGCGCGACAACGACCTCTTCCGGGC
CTACATCACGTGGGCGGAGAAGCACCCACAGTGCCAGAGGCTGAAGCTGAGCGACATGCTGGCCAAACCCCACCAGCGGCTCACCAAGTA
CCCGCTGCTGCTCAAGTCGGTGCTGAGGAAGACCGAGGAGCCGCGCGCCAAGGAGGCCGTCGTCGCCATGATCGGCTCCGTGGAGCGCTT
CATCCACCACGTGAACGCGTGCATGCGGCAGCGGCAGGAGCGGCAGCGGCTGGCGGCCGTGGTGAGCCGCATCGACGCCTACGAGGTGGT
GGAAAGCAGCAGCGACGAAGTGGACAAGCTCCTGAAGGAATTTCTGCACCTGGACTTGACAGCGCCCATCCCTGGCGCCTCCCCGGAGGA
GACGCGGCAGCTGCTGCTGGAGGGGAGCCTGAGGATGAAGGAGGGGAAGGACAGCAAGATGGATGTGTACTGCTTCCTCTTCACGGATCT
GCTGTTGGTGACCAAAGCAGTGAAGAAGGCAGAGAGGACCAGGGTCATCAGGCCACCCCTGCTCGTGGACAAGATTGTGTGCCGGGAGCT
ACGGGACCCTGGGTCCTTCCTCCTTATCTACCTGAATGAGTTTCACAGTGCTGTAGGGGCCTACACGTTCCAGGCCAGTGGCCAGGCCTT
GTGCCGTGGCTGGGTGGACACCATTTACAATGCCCAGAACCAGCTGCAACAGCTGCGTGCACAGGAGCCCCCAGGCAGTCAGCAGCCCCT
GCAGAGCCTGGAAGAGGAGGAGGATGAGCAGGAGGAGGAAGAGGAGGAGGAGGAGGAGGAGGAGGAAGGCGAGGACAGTGGCACTTCAGC
TGCCAGCTCCCCTACCATCATGCGGAAAAGCAGCGGCAGCCCCGACTCTCAGCACTGTGCCTCAGATGGCTCCACGGAGACCCTGGCCAT
GGTTGTGGTAGAGCCTGGGGACACGCTGTCCTCCCCCGAGTTCGACAGCGGTCCTTTCAGCTCCCAGTCTGATGAGACCTCTCTCAGCAC
CACTGCCTCATCTGCCACGCCCACCAGTGAGCTGCTGCCCCTGGGTCCGGTGGACGGCCGCTCCTGCTCCATGGACTCTGCCTACGGCAC
CCTCTCCCCAACCTCCTTACAAGACTTTGTGGCCCCAGGCCCAATGGCAGAGCTAGTGCCTCGGGCCCCAGAGTCCCCACGAGTTCCTTC
CCCTCCACCCTCGCCCCGTCTCCGCCGCCGCACCCCTGTCCAGCTGTTGAGCTGCCCGCCCCACCTGCTCAAGTCTAAGTCCGAGGCCAG
CCTCCTCCAGCTGCTGGCAGGGGCTGGCACCCATGGGACACCCTCTGCCCCCAGCCGCAGCCTGTCAGAGCTCTGCCTGGCTGTTCCAGC
CCCAGGTATTAGGACTCAGGGCTCCCCTCAGGAAGCTGGGCCCAGCTGGGATTGCCGAGGGGCCCCTAGCCCTGGCAGCGGTCCTGGGCT
AGTCGGCTGCCTGGCCGGGGAACCTGCAGGCTCCCACAGGAAGAGGTGTGGAGACCTGCCCTCGGGGGCCTCTCCCAGGGTCCAGCCTGA
GCCCCCACCAGGGGTCTCTGCCCAGCACAGGAAGCTGACCCTGGCCCAGCTCTACCGAATCAGGACCACCCTGCTGCTTAACTCCACGCT
CACTGCCTCGGAGGTCTGAGCAGAGGGAGGCCCCCAAGAGTGCCATTGACCAAGAGACAGCAGACAGCCTGCCTCCTGGGGCGTGCCGGC
ACCTGCTTCAGCTACTGCCTCCTGTATGCATGAGCCGGATGCTGGGCAGGATCCCTGCCTACGCCCGGGCCCGATTTGCGCTTTGCCGGA
CTGGATGGAGTGGAGGAGGCCCAGGCCACAGTACCACCCCACCTGCCCAGGCAGCCCCTCGTCACCTACTCCCCGAAGTTACCAGCTCAG
CTCGAGTCTTCAGGGCTGGGCTCCTAGGCTGCCCATCCTACTTCTACCCTCACTGGCCTCCAGTGGGATTCACTCCTGCCCTGCCCCCAC
CTTCCCAGTCCCACAGGCCACCCCTGGCTTGGGCTGGGTTCTGTGAAGTTACGTATTTATTGAGCTTTTGGTTCTTTTATAAAGACTTGT

>96333_96333_12_UBE4B-PLEKHG5_UBE4B_chr1_10093752_ENST00000377153_PLEKHG5_chr1_6537718_ENST00000400915_length(amino acids)=1043AA_BP=3
MEELSADEVCHHADCQQLHRRGPLNLCEACDSKFHSTMHYDGHVRFDLPPQGSVLARNVSTRSCPPRTSPAVDLEEEEEESSVDGKGDRK
STGLKLSKKKARRRHTDDPSKECFTLKFDLNVDIETEIVPAMKKKSLGEVLLPVFERKGIALGKVDIYLDQSNTPLSLTFEAYRFGGHYL
RVKAPAKPGDEGKVEQGMKDSKSLSLPILRPAGTGPPALERVDAQSRRESLDILAPGRRRKNMSEFLGEASIPGQEPPTPSSCSLPSGSS
GSTNTGDSWKNRAASRFSGFFSSGPSTSAFGREVDKMEQLEGKLHTYSLFGLPRLPRGLRFDHDSWEEEYDEDEDEDNACLRLEDSWREL
IDGHEKLTRRQCHQQEAVWELLHTEASYIRKLRVIINLFLCCLLNLQESGLLCEVEAERLFSNIPEIAQLHRRLWASVMAPVLEKARRTR
ALLQPGDFLKGFKMFGSLFKPYIRYCMEEEGCMEYMRGLLRDNDLFRAYITWAEKHPQCQRLKLSDMLAKPHQRLTKYPLLLKSVLRKTE
EPRAKEAVVAMIGSVERFIHHVNACMRQRQERQRLAAVVSRIDAYEVVESSSDEVDKLLKEFLHLDLTAPIPGASPEETRQLLLEGSLRM
KEGKDSKMDVYCFLFTDLLLVTKAVKKAERTRVIRPPLLVDKIVCRELRDPGSFLLIYLNEFHSAVGAYTFQASGQALCRGWVDTIYNAQ
NQLQQLRAQEPPGSQQPLQSLEEEEDEQEEEEEEEEEEEEGEDSGTSAASSPTIMRKSSGSPDSQHCASDGSTETLAMVVVEPGDTLSSP
EFDSGPFSSQSDETSLSTTASSATPTSELLPLGPVDGRSCSMDSAYGTLSPTSLQDFVAPGPMAELVPRAPESPRVPSPPPSPRLRRRTP
VQLLSCPPHLLKSKSEASLLQLLAGAGTHGTPSAPSRSLSELCLAVPAPGIRTQGSPQEAGPSWDCRGAPSPGSGPGLVGCLAGEPAGSH

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for UBE4B-PLEKHG5

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for UBE4B-PLEKHG5

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for UBE4B-PLEKHG5

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source