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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:UCKL1-ZBTB46 (FusionGDB2 ID:96582)

Fusion Gene Summary for UCKL1-ZBTB46

check button Fusion gene summary
Fusion gene informationFusion gene name: UCKL1-ZBTB46
Fusion gene ID: 96582
HgeneTgene
Gene symbol

UCKL1

ZBTB46

Gene ID

54963

140685

Gene nameuridine-cytidine kinase 1 like 1zinc finger and BTB domain containing 46
SynonymsUCK1L|URKL1BTBD4|BZEL|RINZF|ZNF340|dJ583P15.7|dJ583P15.8
Cytomap

20q13.33

20q13.33

Type of geneprotein-codingprotein-coding
Descriptionuridine-cytidine kinase-like 1UCK1-LIKEzinc finger and BTB domain-containing protein 46BTB (POZ) domain containing 4BTB-ZF protein expressed in effector lymphocytesBTB/POZ domain-containing protein 4zinc finger protein 340
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000354216, ENST00000358711, 
ENST00000369892, ENST00000369908, 
ENST00000492660, 		ENST00000245663, 
ENST00000302995, ENST00000395104, 
ENST00000480766, 
Fusion gene scores* DoF score7 X 6 X 6=25210 X 6 X 6=360
# samples 911
** MAII scorelog2(9/252*10)=-1.48542682717024
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(11/360*10)=-1.71049338280502
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: UCKL1 [Title/Abstract] AND ZBTB46 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointUCKL1(62575750)-ZBTB46(62378654), # samples:2
UCKL1(62572303)-ZBTB46(62422143), # samples:2
Anticipated loss of major functional domain due to fusion event.UCKL1-ZBTB46 seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
UCKL1-ZBTB46 seems lost the major protein functional domain in Tgene partner, which is a transcription factor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across UCKL1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ZBTB46 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUADTCGA-05-4418-01AUCKL1chr20

62575750

-ZBTB46chr20

62378654

-
ChimerDB4STADTCGA-VQ-A928-01AUCKL1chr20

62572303

-ZBTB46chr20

62422143

-


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Fusion Gene ORF analysis for UCKL1-ZBTB46

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000354216ENST00000245663UCKL1chr20

62572303

-ZBTB46chr20

62422143

-
5CDS-5UTRENST00000354216ENST00000302995UCKL1chr20

62572303

-ZBTB46chr20

62422143

-
5CDS-5UTRENST00000354216ENST00000395104UCKL1chr20

62572303

-ZBTB46chr20

62422143

-
5CDS-5UTRENST00000358711ENST00000245663UCKL1chr20

62572303

-ZBTB46chr20

62422143

-
5CDS-5UTRENST00000358711ENST00000302995UCKL1chr20

62572303

-ZBTB46chr20

62422143

-
5CDS-5UTRENST00000358711ENST00000395104UCKL1chr20

62572303

-ZBTB46chr20

62422143

-
5CDS-5UTRENST00000369892ENST00000245663UCKL1chr20

62572303

-ZBTB46chr20

62422143

-
5CDS-5UTRENST00000369892ENST00000302995UCKL1chr20

62572303

-ZBTB46chr20

62422143

-
5CDS-5UTRENST00000369892ENST00000395104UCKL1chr20

62572303

-ZBTB46chr20

62422143

-
5CDS-5UTRENST00000369908ENST00000245663UCKL1chr20

62572303

-ZBTB46chr20

62422143

-
5CDS-5UTRENST00000369908ENST00000302995UCKL1chr20

62572303

-ZBTB46chr20

62422143

-
5CDS-5UTRENST00000369908ENST00000395104UCKL1chr20

62572303

-ZBTB46chr20

62422143

-
5CDS-intronENST00000354216ENST00000480766UCKL1chr20

62575750

-ZBTB46chr20

62378654

-
5CDS-intronENST00000354216ENST00000480766UCKL1chr20

62572303

-ZBTB46chr20

62422143

-
5CDS-intronENST00000358711ENST00000480766UCKL1chr20

62575750

-ZBTB46chr20

62378654

-
5CDS-intronENST00000358711ENST00000480766UCKL1chr20

62572303

-ZBTB46chr20

62422143

-
5CDS-intronENST00000369892ENST00000480766UCKL1chr20

62575750

-ZBTB46chr20

62378654

-
5CDS-intronENST00000369892ENST00000480766UCKL1chr20

62572303

-ZBTB46chr20

62422143

-
5CDS-intronENST00000369908ENST00000480766UCKL1chr20

62575750

-ZBTB46chr20

62378654

-
5CDS-intronENST00000369908ENST00000480766UCKL1chr20

62572303

-ZBTB46chr20

62422143

-
Frame-shiftENST00000354216ENST00000302995UCKL1chr20

62575750

-ZBTB46chr20

62378654

-
Frame-shiftENST00000354216ENST00000395104UCKL1chr20

62575750

-ZBTB46chr20

62378654

-
Frame-shiftENST00000358711ENST00000302995UCKL1chr20

62575750

-ZBTB46chr20

62378654

-
Frame-shiftENST00000358711ENST00000395104UCKL1chr20

62575750

-ZBTB46chr20

62378654

-
Frame-shiftENST00000369892ENST00000302995UCKL1chr20

62575750

-ZBTB46chr20

62378654

-
Frame-shiftENST00000369892ENST00000395104UCKL1chr20

62575750

-ZBTB46chr20

62378654

-
Frame-shiftENST00000369908ENST00000302995UCKL1chr20

62575750

-ZBTB46chr20

62378654

-
Frame-shiftENST00000369908ENST00000395104UCKL1chr20

62575750

-ZBTB46chr20

62378654

-
In-frameENST00000354216ENST00000245663UCKL1chr20

62575750

-ZBTB46chr20

62378654

-
In-frameENST00000358711ENST00000245663UCKL1chr20

62575750

-ZBTB46chr20

62378654

-
In-frameENST00000369892ENST00000245663UCKL1chr20

62575750

-ZBTB46chr20

62378654

-
In-frameENST00000369908ENST00000245663UCKL1chr20

62575750

-ZBTB46chr20

62378654

-
intron-3CDSENST00000492660ENST00000245663UCKL1chr20

62575750

-ZBTB46chr20

62378654

-
intron-3CDSENST00000492660ENST00000302995UCKL1chr20

62575750

-ZBTB46chr20

62378654

-
intron-3CDSENST00000492660ENST00000395104UCKL1chr20

62575750

-ZBTB46chr20

62378654

-
intron-5UTRENST00000492660ENST00000245663UCKL1chr20

62572303

-ZBTB46chr20

62422143

-
intron-5UTRENST00000492660ENST00000302995UCKL1chr20

62572303

-ZBTB46chr20

62422143

-
intron-5UTRENST00000492660ENST00000395104UCKL1chr20

62572303

-ZBTB46chr20

62422143

-
intron-intronENST00000492660ENST00000480766UCKL1chr20

62575750

-ZBTB46chr20

62378654

-
intron-intronENST00000492660ENST00000480766UCKL1chr20

62572303

-ZBTB46chr20

62422143

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000354216UCKL1chr2062575750-ENST00000245663ZBTB46chr2062378654-45859491548241435
ENST00000369892UCKL1chr2062575750-ENST00000245663ZBTB46chr2062378654-45869501549242435
ENST00000358711UCKL1chr2062575750-ENST00000245663ZBTB46chr2062378654-45869501549242435
ENST00000369908UCKL1chr2062575750-ENST00000245663ZBTB46chr2062378654-479711612221532436

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000354216ENST00000245663UCKL1chr2062575750-ZBTB46chr2062378654-0.0017834720.99821645
ENST00000369892ENST00000245663UCKL1chr2062575750-ZBTB46chr2062378654-0.0017889450.998211
ENST00000358711ENST00000245663UCKL1chr2062575750-ZBTB46chr2062378654-0.0017889450.998211
ENST00000369908ENST00000245663UCKL1chr2062575750-ZBTB46chr2062378654-0.0027923760.9972076

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Fusion Genomic Features for UCKL1-ZBTB46


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for UCKL1-ZBTB46


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr20:62575750/chr20:62378654)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneUCKL1chr20:62575750chr20:62378654ENST00000354216-715105_112302549.0Nucleotide bindingATP
HgeneUCKL1chr20:62575750chr20:62378654ENST00000358711-713105_112302412.6666666666667Nucleotide bindingATP
HgeneUCKL1chr20:62575750chr20:62378654ENST00000369908-715105_112287534.0Nucleotide bindingATP

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneZBTB46chr20:62575750chr20:62378654ENST000002456633531_99466590.0DomainBTB
TgeneZBTB46chr20:62575750chr20:62378654ENST000003029953731_99466374.3333333333333DomainBTB
TgeneZBTB46chr20:62575750chr20:62378654ENST000003951042431_99466590.0DomainBTB
TgeneZBTB46chr20:62575750chr20:62378654ENST0000024566335418_436466590.0Zinc fingerC2H2-type 1
TgeneZBTB46chr20:62575750chr20:62378654ENST0000024566335446_468466590.0Zinc fingerC2H2-type 2
TgeneZBTB46chr20:62575750chr20:62378654ENST0000030299537418_436466374.3333333333333Zinc fingerC2H2-type 1
TgeneZBTB46chr20:62575750chr20:62378654ENST0000030299537446_468466374.3333333333333Zinc fingerC2H2-type 2
TgeneZBTB46chr20:62575750chr20:62378654ENST0000039510424418_436466590.0Zinc fingerC2H2-type 1
TgeneZBTB46chr20:62575750chr20:62378654ENST0000039510424446_468466590.0Zinc fingerC2H2-type 2


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Fusion Gene Sequence for UCKL1-ZBTB46


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>96582_96582_1_UCKL1-ZBTB46_UCKL1_chr20_62575750_ENST00000354216_ZBTB46_chr20_62378654_ENST00000245663_length(transcript)=4585nt_BP=949nt
TGCGCGCCGCCCGGCCAGGCCCGCAAAGAGGCCTCCGAGCGCCATGGCTGCGCCCCCGGCCCGCGCGGACGCTGATCCTTCGCCCACGTC
GCCACCTACGGCCCGAGACACACCAGGCCGGCAGGCTGAGAAAAGCGAGACCGCGTGCGAGGACCGCAGCAATGCAGAGTCCCTGGACAG
GCTCCTGCCACCTGTGGGCACTGGGCGCTCTCCCCGGAAGCGGACCACCAGCCAGTGCAAGTCAGAGCCTCCCCTGCTGCGTACAAGCAA
GCGTACCATCTACACCGCCGGGCGGCCGCCCTGGTACAATGAACACGGCACGCAATCCAAAGAGGCCTTCGCCATCGGCTTGGGAGGCGG
CAGTGCCTCTGGGAAGACCACTGTGGCCAGAATGATCATCGAGGCCCTGGATGTGCCCTGGGTGGTCTTGCTGTCCATGGACTCCTTCTA
CAAGGTGCTGACTGAGCAGCAGCAGGAACAGGCCGCACACAACAACTTCAACTTCGACCACCCAGATGCCTTTGACTTCGACCTCATCAT
TTCCACCCTCAAGAAGCTGAAGCAGGGGAAGAGTGTCAAGGTGCCCATTTATGACTTCACCACGCACAGCCGGAAGAAGGACTGGAAAAC
ACTGTATGGTGCAAACGTCATCATCTTTGAGGGCATCATGGCCTTTGCTGACAAGACACTGTTGGAGCTCCTGGACATGAAGATCTTTGT
GGACACAGACTCCGACATCCGCCTGGTACGGCGGCTGCGCCGGGACATCAGTGAGCGCGGCCGGGACATCGAGGGTGTCATCAAGCAGTA
CAACAAGTTTGTCAAGCCCTCCTTCGACCAGTACATCCAGCCCACCATGCGCCTGGCAGACATCGTGGTCCCCAGAGGGAGCGGCAACAC
GGTGGCCATCGACCTGATTGTGCAGCACGTGCACAGCCAGCTGGAGGAGGTCCACAGCAAGGACAAGAAGTATGTGTGCAAGGTGTGCAG
CCGCGTCTTCATGTCCGCCGCCAGCGTGGGCATCAGGCATGGCTCCAGGCGCCACGGTGTGTGCACCGACTGTGCTGGCCGCGGCATGGC
CGGGCCCCTGGACCATGGCGGCGGAGGCGGCGAGGGCTCTCCAGAGGCGCTGTTCCCAGGCGACGGGCCCTATCTGGAGGACCCTGAGGA
CCCACGAGGGGAGGCGGAGGAGCTGGGCGAGGACGACGAGGGCCTGGCCCCTGAGGATGCGCTGTTGGCGGACGACAAGGATGAGGAAGA
CTCGCCGCGGCCGCGCAGCCCCCCAGGAGGCCCTGACAAGGACTTCGCCTGGCTCTCCTAGGCCCGCCCGCCGGCAGGGTCGGTGGCTGC
CTCGCTCCGTCCACCCGTGTGTGTGTCCGGTGGGTCTCCACTGCGGGGCCAGGGCCACGCTCACCCCTCTCGCGGCCCCTCCTCTGCTTC
CCCCTGAACCCACCCCCCACGGAAACCAGCCCTGCGGGCTAAGCAGGTGCGACCCCAGCAAGAGGGGTGCTCTGGGACCAGACATGAAGT
GAGTTGGGGGAGGGCACAGGGTGGGTTTGAGTGAAGGGAGAGCACGGTCCTAAGTCCCCAGCAGGTGGTGCGGGTGTGTGAGTGGCCCCT
GTGATGGCCAGCCTGGCTTGGACACGTGATGGGCCTGTGGCCGGGTCCAGTGGGCACTGGGCGGGGTGGTGTGTTCGGCCCAGAGGCCCC
TGGCCTGAGCAGGTGCAGAGTTTTACAGACACCCGGTCAGCCCGGCTGGAGCCCGCCCTCCCCTCCCCTAGCAGCCAGGTCACTGCCTGT
GGCTGCAGCCGTGGCCCGTGGTGCAGCCGTGGCCCATGGCAGCCTGTAGAATCCAGGTGCACAGAGAGCCCTGCCACCGTCTTACCTCTG
GGCTTTGGTGCTTAACACACAACACAGCTGCAGACCCTGCTGGAGGCCGAGGGCTCCAGGTGCTATCTTAGGTGGACACAGCCCTGGGGG
CTCCTTCCAGGAGGGGACCCTCAGCCCTGTGCCCCCCACCACTTCAGGCCACACCAGGTTCCCTCTGCAAGGGCCTCGGCTCAGTCGTGT
GCACTTCCTCGGAGAGCCTTGGGCTGCCACGTCCACCCCGGGCTCTGCCCGTCCTGTTCTGCCCATGGCCCAGCCCGGCCGCTCCTGCTG
ACCCCTCCTGGACGGGCTGGAGCTGGGCTCCTGCCTTTGCTGCTAACACTGGAGGCGGTGTTCCTAACTGCAGTGTGCTGCTTACACCTC
CCCGCGTGGGTAACCAAATTTTTAAGTAGTCAGAGACATATCGAGGTAGTTACATAAAATTATTTTGTTTGGCATTATTTTTCTCACTCG
AAGAAACTATATAGGGTTGTTTTTCCTTTAGCTTGTGCTCAAGTCCTCTTGCTGTGTTTTCAGAAGCACTCACATGTTCTTTCTTTTCCT
GAGTGAAAAGCAAAGGTCCCACGGTGTGTGCTGTGGTGCACCGCCTGGCTTTGGGGGTCCCGGAGGCAGGCTGCCTAGACTCACAGCCTC
GGGACCGTTGCCACGGCCTGTCTTCTCGTTCAGGCCTGCCTCTGACAGCACTCACCATGAGGACATTCCATCCTTCACCCCCTCCTCTGG
CACAGGCCACCACTGCGGTGCTGTGCCTTCAGATGGGAGGTGGGCGCGGTGGCCTCCTCCTTCCCTCCAGGACCTGCCCGTGTGAAGACC
CCCCGGAGTGCTGAGCTTCAGGGCTGCGTGGAAAGAGTTTTTACTCTCTTTTTCTAGCCTGTATACCAGGCTTTTCCCCACATTGTCAGG
TAGAGCACCAGCTTCCCTGACCGCTGCTGCTCGGGGAGGGCTGGGGCTGGCCGGGGGTCCTGTGGAGGAGTACATGGAGGACTCCAGGTA
CAGCGCAGGAGTCACGGCTTTTGTTTTTTGACATTGGCCCCCGGTTCTACCAATGACAGGGTGCCCTGGCTGGAGCTGTCATCACACACA
CCCCTCAGCTCGGAGGCTGTGGGCTCCTCAAAGCTGGAGAAAGAGGCCAAGATTTTTCTGCACACGGAGTGTGGGGATAGGAGCCGGGCC
AAGCGCTGGCCCCTCAGCGGTGAGCCCTGCCCACTCTTACCGAGCAAGGTGGGTGGCTCTGGCACGAGTCCCCCAGGGGGAGAGCATGGC
TACCAGGGAGCTGCAGCGGAGCCCTCCAGCCCTCACCCCAGGCCAGCCCCACCCCGGCCTCTTTGAGAATTCTCAGAACTTTGTACCTTT
CCCCTGATTTTTAAACCCTTTTTCTAAACAGACTGACTTTCTTACAAAATGCATTTGGAAACCAGACCTTTGCTACCCACCAATGTCTCT
GGGTTTTGTACCAGTCCCTGCTCTCAGGCCACCCTGCCCAGGACCCAGGCCCGCCTCCCCCTCCACACTCAGGATGTCCTGCTCCATCTG
GCCGGCTCACTCCGTGTGGCCTGCCTTTGCTGACCGTTTTGGGGTTCCCCGCCGGAGCTACAGGGGCATTTTCTTCCCTAAAACCAACAG
TGTCCCACTGACCTCCCCAAGTGTTTGCTGCGTGGCAGATTTCCTGTTCTTGTTCGCAGTTTGCCGACTGAAGAGTGTGGGATTTCCGAG
GCCCAGGTGAGCACGTCCATCTCAGGAGGCGTGGAGGGAAAAGACATGTCATGAAGGGTTTTTTTTATGTGACTGATTTTTTTTTAAATC
GATGTTCAAACTAATAAATATTTTTTTATGAAGAGGAAAAATGTGTAGATTACATTTCACATTTTGTATTTTTGTTTGTGTCTGTTTGTA
TTTTGGTGTTTACAACACCAAAGTGGGAAATACAGTCCATTGGGGATGGTGTTATTTGGGGGCGGGGAGGGGGCAGGGACACCACGATTT
TTCTGTCAAGCTCTGGATCCTGACCAGGTTGTACACTGGGGCTCTCTGAGCTTTGGGACACAGGACACTGCCAGGGCTACGTAGGGAACT
GACTCAGAAGACGCAGCTTACTGCTTCCAACTTTGCACATCTTCCTCTTTAAAAAACTGAGAAAATGCAAAAACTGGAACTTTTTGCAAT
ATTATAAAAGAAGTAATCTTATTTTAGCTCATTCTGTGACATGTGCGACTCTTAAGAAAGCCATACTTAATGGTGGTGGTTTTTTTTAGA
TCTTATATTGTGTTTTGTATGCAGCCCTTTTAGAACTACTTGTAGTGAGGGTGCTGTGTGTGCTTTTCTTAAATATTTATTTTTTTCAAC
ATGCTTTCAACCTGTCAACAAAAACAAAACACACAAAAAAAGGGCAGTGTTTGAAGATTGTTGATTTTTTTCTGGGGATAATCTATATTA
TATTGACTTCCTATTACTTATTATAAACCTGTGTTTGTATTGGAGATGTGTCTACTATTGGGGGAAGAGGTTCTCGTAATCGCTCGGTGG
GAAATCATGGCTCTGCCGTCCTGCCTCTCTGTGGCCGTGGGTTCACGTGGCCTCTGCGGTGAGTCTCCAAGTTTCTGCCTAGGCGCCTGT

>96582_96582_1_UCKL1-ZBTB46_UCKL1_chr20_62575750_ENST00000354216_ZBTB46_chr20_62378654_ENST00000245663_length(amino acids)=435AA_BP=1
MCPPPTHFMSGPRAPLLLGSHLLSPQGWFPWGVGSGGSRGGAARGVSVALAPQWRPTGHTHGWTERGSHRPCRRAGLGEPGEVLVRASWG
AARPRRVFLILVVRQQRILRGQALVVLAQLLRLPSWVLRVLQIGPVAWEQRLWRALAASAAMVQGPGHAAASTVGAHTVAPGAMPDAHAG
GGHEDAAAHLAHILLVLAVDLLQLAVHVLHNQVDGHRVAAPSGDHDVCQAHGGLDVLVEGGLDKLVVLLDDTLDVPAALTDVPAQPPYQA
DVGVCVHKDLHVQELQQCLVSKGHDALKDDDVCTIQCFPVLLPAVRGEVINGHLDTLPLLQLLEGGNDEVEVKGIWVVEVEVVVCGLFLL

--------------------------------------------------------------
>96582_96582_2_UCKL1-ZBTB46_UCKL1_chr20_62575750_ENST00000358711_ZBTB46_chr20_62378654_ENST00000245663_length(transcript)=4586nt_BP=950nt
ATGCGCGCCGCCCGGCCAGGCCCGCAAAGAGGCCTCCGAGCGCCATGGCTGCGCCCCCGGCCCGCGCGGACGCTGATCCTTCGCCCACGT
CGCCACCTACGGCCCGAGACACACCAGGCCGGCAGGCTGAGAAAAGCGAGACCGCGTGCGAGGACCGCAGCAATGCAGAGTCCCTGGACA
GGCTCCTGCCACCTGTGGGCACTGGGCGCTCTCCCCGGAAGCGGACCACCAGCCAGTGCAAGTCAGAGCCTCCCCTGCTGCGTACAAGCA
AGCGTACCATCTACACCGCCGGGCGGCCGCCCTGGTACAATGAACACGGCACGCAATCCAAAGAGGCCTTCGCCATCGGCTTGGGAGGCG
GCAGTGCCTCTGGGAAGACCACTGTGGCCAGAATGATCATCGAGGCCCTGGATGTGCCCTGGGTGGTCTTGCTGTCCATGGACTCCTTCT
ACAAGGTGCTGACTGAGCAGCAGCAGGAACAGGCCGCACACAACAACTTCAACTTCGACCACCCAGATGCCTTTGACTTCGACCTCATCA
TTTCCACCCTCAAGAAGCTGAAGCAGGGGAAGAGTGTCAAGGTGCCCATTTATGACTTCACCACGCACAGCCGGAAGAAGGACTGGAAAA
CACTGTATGGTGCAAACGTCATCATCTTTGAGGGCATCATGGCCTTTGCTGACAAGACACTGTTGGAGCTCCTGGACATGAAGATCTTTG
TGGACACAGACTCCGACATCCGCCTGGTACGGCGGCTGCGCCGGGACATCAGTGAGCGCGGCCGGGACATCGAGGGTGTCATCAAGCAGT
ACAACAAGTTTGTCAAGCCCTCCTTCGACCAGTACATCCAGCCCACCATGCGCCTGGCAGACATCGTGGTCCCCAGAGGGAGCGGCAACA
CGGTGGCCATCGACCTGATTGTGCAGCACGTGCACAGCCAGCTGGAGGAGGTCCACAGCAAGGACAAGAAGTATGTGTGCAAGGTGTGCA
GCCGCGTCTTCATGTCCGCCGCCAGCGTGGGCATCAGGCATGGCTCCAGGCGCCACGGTGTGTGCACCGACTGTGCTGGCCGCGGCATGG
CCGGGCCCCTGGACCATGGCGGCGGAGGCGGCGAGGGCTCTCCAGAGGCGCTGTTCCCAGGCGACGGGCCCTATCTGGAGGACCCTGAGG
ACCCACGAGGGGAGGCGGAGGAGCTGGGCGAGGACGACGAGGGCCTGGCCCCTGAGGATGCGCTGTTGGCGGACGACAAGGATGAGGAAG
ACTCGCCGCGGCCGCGCAGCCCCCCAGGAGGCCCTGACAAGGACTTCGCCTGGCTCTCCTAGGCCCGCCCGCCGGCAGGGTCGGTGGCTG
CCTCGCTCCGTCCACCCGTGTGTGTGTCCGGTGGGTCTCCACTGCGGGGCCAGGGCCACGCTCACCCCTCTCGCGGCCCCTCCTCTGCTT
CCCCCTGAACCCACCCCCCACGGAAACCAGCCCTGCGGGCTAAGCAGGTGCGACCCCAGCAAGAGGGGTGCTCTGGGACCAGACATGAAG
TGAGTTGGGGGAGGGCACAGGGTGGGTTTGAGTGAAGGGAGAGCACGGTCCTAAGTCCCCAGCAGGTGGTGCGGGTGTGTGAGTGGCCCC
TGTGATGGCCAGCCTGGCTTGGACACGTGATGGGCCTGTGGCCGGGTCCAGTGGGCACTGGGCGGGGTGGTGTGTTCGGCCCAGAGGCCC
CTGGCCTGAGCAGGTGCAGAGTTTTACAGACACCCGGTCAGCCCGGCTGGAGCCCGCCCTCCCCTCCCCTAGCAGCCAGGTCACTGCCTG
TGGCTGCAGCCGTGGCCCGTGGTGCAGCCGTGGCCCATGGCAGCCTGTAGAATCCAGGTGCACAGAGAGCCCTGCCACCGTCTTACCTCT
GGGCTTTGGTGCTTAACACACAACACAGCTGCAGACCCTGCTGGAGGCCGAGGGCTCCAGGTGCTATCTTAGGTGGACACAGCCCTGGGG
GCTCCTTCCAGGAGGGGACCCTCAGCCCTGTGCCCCCCACCACTTCAGGCCACACCAGGTTCCCTCTGCAAGGGCCTCGGCTCAGTCGTG
TGCACTTCCTCGGAGAGCCTTGGGCTGCCACGTCCACCCCGGGCTCTGCCCGTCCTGTTCTGCCCATGGCCCAGCCCGGCCGCTCCTGCT
GACCCCTCCTGGACGGGCTGGAGCTGGGCTCCTGCCTTTGCTGCTAACACTGGAGGCGGTGTTCCTAACTGCAGTGTGCTGCTTACACCT
CCCCGCGTGGGTAACCAAATTTTTAAGTAGTCAGAGACATATCGAGGTAGTTACATAAAATTATTTTGTTTGGCATTATTTTTCTCACTC
GAAGAAACTATATAGGGTTGTTTTTCCTTTAGCTTGTGCTCAAGTCCTCTTGCTGTGTTTTCAGAAGCACTCACATGTTCTTTCTTTTCC
TGAGTGAAAAGCAAAGGTCCCACGGTGTGTGCTGTGGTGCACCGCCTGGCTTTGGGGGTCCCGGAGGCAGGCTGCCTAGACTCACAGCCT
CGGGACCGTTGCCACGGCCTGTCTTCTCGTTCAGGCCTGCCTCTGACAGCACTCACCATGAGGACATTCCATCCTTCACCCCCTCCTCTG
GCACAGGCCACCACTGCGGTGCTGTGCCTTCAGATGGGAGGTGGGCGCGGTGGCCTCCTCCTTCCCTCCAGGACCTGCCCGTGTGAAGAC
CCCCCGGAGTGCTGAGCTTCAGGGCTGCGTGGAAAGAGTTTTTACTCTCTTTTTCTAGCCTGTATACCAGGCTTTTCCCCACATTGTCAG
GTAGAGCACCAGCTTCCCTGACCGCTGCTGCTCGGGGAGGGCTGGGGCTGGCCGGGGGTCCTGTGGAGGAGTACATGGAGGACTCCAGGT
ACAGCGCAGGAGTCACGGCTTTTGTTTTTTGACATTGGCCCCCGGTTCTACCAATGACAGGGTGCCCTGGCTGGAGCTGTCATCACACAC
ACCCCTCAGCTCGGAGGCTGTGGGCTCCTCAAAGCTGGAGAAAGAGGCCAAGATTTTTCTGCACACGGAGTGTGGGGATAGGAGCCGGGC
CAAGCGCTGGCCCCTCAGCGGTGAGCCCTGCCCACTCTTACCGAGCAAGGTGGGTGGCTCTGGCACGAGTCCCCCAGGGGGAGAGCATGG
CTACCAGGGAGCTGCAGCGGAGCCCTCCAGCCCTCACCCCAGGCCAGCCCCACCCCGGCCTCTTTGAGAATTCTCAGAACTTTGTACCTT
TCCCCTGATTTTTAAACCCTTTTTCTAAACAGACTGACTTTCTTACAAAATGCATTTGGAAACCAGACCTTTGCTACCCACCAATGTCTC
TGGGTTTTGTACCAGTCCCTGCTCTCAGGCCACCCTGCCCAGGACCCAGGCCCGCCTCCCCCTCCACACTCAGGATGTCCTGCTCCATCT
GGCCGGCTCACTCCGTGTGGCCTGCCTTTGCTGACCGTTTTGGGGTTCCCCGCCGGAGCTACAGGGGCATTTTCTTCCCTAAAACCAACA
GTGTCCCACTGACCTCCCCAAGTGTTTGCTGCGTGGCAGATTTCCTGTTCTTGTTCGCAGTTTGCCGACTGAAGAGTGTGGGATTTCCGA
GGCCCAGGTGAGCACGTCCATCTCAGGAGGCGTGGAGGGAAAAGACATGTCATGAAGGGTTTTTTTTATGTGACTGATTTTTTTTTAAAT
CGATGTTCAAACTAATAAATATTTTTTTATGAAGAGGAAAAATGTGTAGATTACATTTCACATTTTGTATTTTTGTTTGTGTCTGTTTGT
ATTTTGGTGTTTACAACACCAAAGTGGGAAATACAGTCCATTGGGGATGGTGTTATTTGGGGGCGGGGAGGGGGCAGGGACACCACGATT
TTTCTGTCAAGCTCTGGATCCTGACCAGGTTGTACACTGGGGCTCTCTGAGCTTTGGGACACAGGACACTGCCAGGGCTACGTAGGGAAC
TGACTCAGAAGACGCAGCTTACTGCTTCCAACTTTGCACATCTTCCTCTTTAAAAAACTGAGAAAATGCAAAAACTGGAACTTTTTGCAA
TATTATAAAAGAAGTAATCTTATTTTAGCTCATTCTGTGACATGTGCGACTCTTAAGAAAGCCATACTTAATGGTGGTGGTTTTTTTTAG
ATCTTATATTGTGTTTTGTATGCAGCCCTTTTAGAACTACTTGTAGTGAGGGTGCTGTGTGTGCTTTTCTTAAATATTTATTTTTTTCAA
CATGCTTTCAACCTGTCAACAAAAACAAAACACACAAAAAAAGGGCAGTGTTTGAAGATTGTTGATTTTTTTCTGGGGATAATCTATATT
ATATTGACTTCCTATTACTTATTATAAACCTGTGTTTGTATTGGAGATGTGTCTACTATTGGGGGAAGAGGTTCTCGTAATCGCTCGGTG
GGAAATCATGGCTCTGCCGTCCTGCCTCTCTGTGGCCGTGGGTTCACGTGGCCTCTGCGGTGAGTCTCCAAGTTTCTGCCTAGGCGCCTG

>96582_96582_2_UCKL1-ZBTB46_UCKL1_chr20_62575750_ENST00000358711_ZBTB46_chr20_62378654_ENST00000245663_length(amino acids)=435AA_BP=1
MCPPPTHFMSGPRAPLLLGSHLLSPQGWFPWGVGSGGSRGGAARGVSVALAPQWRPTGHTHGWTERGSHRPCRRAGLGEPGEVLVRASWG
AARPRRVFLILVVRQQRILRGQALVVLAQLLRLPSWVLRVLQIGPVAWEQRLWRALAASAAMVQGPGHAAASTVGAHTVAPGAMPDAHAG
GGHEDAAAHLAHILLVLAVDLLQLAVHVLHNQVDGHRVAAPSGDHDVCQAHGGLDVLVEGGLDKLVVLLDDTLDVPAALTDVPAQPPYQA
DVGVCVHKDLHVQELQQCLVSKGHDALKDDDVCTIQCFPVLLPAVRGEVINGHLDTLPLLQLLEGGNDEVEVKGIWVVEVEVVVCGLFLL

--------------------------------------------------------------
>96582_96582_3_UCKL1-ZBTB46_UCKL1_chr20_62575750_ENST00000369892_ZBTB46_chr20_62378654_ENST00000245663_length(transcript)=4586nt_BP=950nt
ATGCGCGCCGCCCGGCCAGGCCCGCAAAGAGGCCTCCGAGCGCCATGGCTGCGCCCCCGGCCCGCGCGGACGCTGATCCTTCGCCCACGT
CGCCACCTACGGCCCGAGACACACCAGGCCGGCAGGCTGAGAAAAGCGAGACCGCGTGCGAGGACCGCAGCAATGCAGAGTCCCTGGACA
GGCTCCTGCCACCTGTGGGCACTGGGCGCTCTCCCCGGAAGCGGACCACCAGCCAGTGCAAGTCAGAGCCTCCCCTGCTGCGTACAAGCA
AGCGTACCATCTACACCGCCGGGCGGCCGCCCTGGTACAATGAACACGGCACGCAATCCAAAGAGGCCTTCGCCATCGGCTTGGGAGGCG
GCAGTGCCTCTGGGAAGACCACTGTGGCCAGAATGATCATCGAGGCCCTGGATGTGCCCTGGGTGGTCTTGCTGTCCATGGACTCCTTCT
ACAAGGTGCTGACTGAGCAGCAGCAGGAACAGGCCGCACACAACAACTTCAACTTCGACCACCCAGATGCCTTTGACTTCGACCTCATCA
TTTCCACCCTCAAGAAGCTGAAGCAGGGGAAGAGTGTCAAGGTGCCCATTTATGACTTCACCACGCACAGCCGGAAGAAGGACTGGAAAA
CACTGTATGGTGCAAACGTCATCATCTTTGAGGGCATCATGGCCTTTGCTGACAAGACACTGTTGGAGCTCCTGGACATGAAGATCTTTG
TGGACACAGACTCCGACATCCGCCTGGTACGGCGGCTGCGCCGGGACATCAGTGAGCGCGGCCGGGACATCGAGGGTGTCATCAAGCAGT
ACAACAAGTTTGTCAAGCCCTCCTTCGACCAGTACATCCAGCCCACCATGCGCCTGGCAGACATCGTGGTCCCCAGAGGGAGCGGCAACA
CGGTGGCCATCGACCTGATTGTGCAGCACGTGCACAGCCAGCTGGAGGAGGTCCACAGCAAGGACAAGAAGTATGTGTGCAAGGTGTGCA
GCCGCGTCTTCATGTCCGCCGCCAGCGTGGGCATCAGGCATGGCTCCAGGCGCCACGGTGTGTGCACCGACTGTGCTGGCCGCGGCATGG
CCGGGCCCCTGGACCATGGCGGCGGAGGCGGCGAGGGCTCTCCAGAGGCGCTGTTCCCAGGCGACGGGCCCTATCTGGAGGACCCTGAGG
ACCCACGAGGGGAGGCGGAGGAGCTGGGCGAGGACGACGAGGGCCTGGCCCCTGAGGATGCGCTGTTGGCGGACGACAAGGATGAGGAAG
ACTCGCCGCGGCCGCGCAGCCCCCCAGGAGGCCCTGACAAGGACTTCGCCTGGCTCTCCTAGGCCCGCCCGCCGGCAGGGTCGGTGGCTG
CCTCGCTCCGTCCACCCGTGTGTGTGTCCGGTGGGTCTCCACTGCGGGGCCAGGGCCACGCTCACCCCTCTCGCGGCCCCTCCTCTGCTT
CCCCCTGAACCCACCCCCCACGGAAACCAGCCCTGCGGGCTAAGCAGGTGCGACCCCAGCAAGAGGGGTGCTCTGGGACCAGACATGAAG
TGAGTTGGGGGAGGGCACAGGGTGGGTTTGAGTGAAGGGAGAGCACGGTCCTAAGTCCCCAGCAGGTGGTGCGGGTGTGTGAGTGGCCCC
TGTGATGGCCAGCCTGGCTTGGACACGTGATGGGCCTGTGGCCGGGTCCAGTGGGCACTGGGCGGGGTGGTGTGTTCGGCCCAGAGGCCC
CTGGCCTGAGCAGGTGCAGAGTTTTACAGACACCCGGTCAGCCCGGCTGGAGCCCGCCCTCCCCTCCCCTAGCAGCCAGGTCACTGCCTG
TGGCTGCAGCCGTGGCCCGTGGTGCAGCCGTGGCCCATGGCAGCCTGTAGAATCCAGGTGCACAGAGAGCCCTGCCACCGTCTTACCTCT
GGGCTTTGGTGCTTAACACACAACACAGCTGCAGACCCTGCTGGAGGCCGAGGGCTCCAGGTGCTATCTTAGGTGGACACAGCCCTGGGG
GCTCCTTCCAGGAGGGGACCCTCAGCCCTGTGCCCCCCACCACTTCAGGCCACACCAGGTTCCCTCTGCAAGGGCCTCGGCTCAGTCGTG
TGCACTTCCTCGGAGAGCCTTGGGCTGCCACGTCCACCCCGGGCTCTGCCCGTCCTGTTCTGCCCATGGCCCAGCCCGGCCGCTCCTGCT
GACCCCTCCTGGACGGGCTGGAGCTGGGCTCCTGCCTTTGCTGCTAACACTGGAGGCGGTGTTCCTAACTGCAGTGTGCTGCTTACACCT
CCCCGCGTGGGTAACCAAATTTTTAAGTAGTCAGAGACATATCGAGGTAGTTACATAAAATTATTTTGTTTGGCATTATTTTTCTCACTC
GAAGAAACTATATAGGGTTGTTTTTCCTTTAGCTTGTGCTCAAGTCCTCTTGCTGTGTTTTCAGAAGCACTCACATGTTCTTTCTTTTCC
TGAGTGAAAAGCAAAGGTCCCACGGTGTGTGCTGTGGTGCACCGCCTGGCTTTGGGGGTCCCGGAGGCAGGCTGCCTAGACTCACAGCCT
CGGGACCGTTGCCACGGCCTGTCTTCTCGTTCAGGCCTGCCTCTGACAGCACTCACCATGAGGACATTCCATCCTTCACCCCCTCCTCTG
GCACAGGCCACCACTGCGGTGCTGTGCCTTCAGATGGGAGGTGGGCGCGGTGGCCTCCTCCTTCCCTCCAGGACCTGCCCGTGTGAAGAC
CCCCCGGAGTGCTGAGCTTCAGGGCTGCGTGGAAAGAGTTTTTACTCTCTTTTTCTAGCCTGTATACCAGGCTTTTCCCCACATTGTCAG
GTAGAGCACCAGCTTCCCTGACCGCTGCTGCTCGGGGAGGGCTGGGGCTGGCCGGGGGTCCTGTGGAGGAGTACATGGAGGACTCCAGGT
ACAGCGCAGGAGTCACGGCTTTTGTTTTTTGACATTGGCCCCCGGTTCTACCAATGACAGGGTGCCCTGGCTGGAGCTGTCATCACACAC
ACCCCTCAGCTCGGAGGCTGTGGGCTCCTCAAAGCTGGAGAAAGAGGCCAAGATTTTTCTGCACACGGAGTGTGGGGATAGGAGCCGGGC
CAAGCGCTGGCCCCTCAGCGGTGAGCCCTGCCCACTCTTACCGAGCAAGGTGGGTGGCTCTGGCACGAGTCCCCCAGGGGGAGAGCATGG
CTACCAGGGAGCTGCAGCGGAGCCCTCCAGCCCTCACCCCAGGCCAGCCCCACCCCGGCCTCTTTGAGAATTCTCAGAACTTTGTACCTT
TCCCCTGATTTTTAAACCCTTTTTCTAAACAGACTGACTTTCTTACAAAATGCATTTGGAAACCAGACCTTTGCTACCCACCAATGTCTC
TGGGTTTTGTACCAGTCCCTGCTCTCAGGCCACCCTGCCCAGGACCCAGGCCCGCCTCCCCCTCCACACTCAGGATGTCCTGCTCCATCT
GGCCGGCTCACTCCGTGTGGCCTGCCTTTGCTGACCGTTTTGGGGTTCCCCGCCGGAGCTACAGGGGCATTTTCTTCCCTAAAACCAACA
GTGTCCCACTGACCTCCCCAAGTGTTTGCTGCGTGGCAGATTTCCTGTTCTTGTTCGCAGTTTGCCGACTGAAGAGTGTGGGATTTCCGA
GGCCCAGGTGAGCACGTCCATCTCAGGAGGCGTGGAGGGAAAAGACATGTCATGAAGGGTTTTTTTTATGTGACTGATTTTTTTTTAAAT
CGATGTTCAAACTAATAAATATTTTTTTATGAAGAGGAAAAATGTGTAGATTACATTTCACATTTTGTATTTTTGTTTGTGTCTGTTTGT
ATTTTGGTGTTTACAACACCAAAGTGGGAAATACAGTCCATTGGGGATGGTGTTATTTGGGGGCGGGGAGGGGGCAGGGACACCACGATT
TTTCTGTCAAGCTCTGGATCCTGACCAGGTTGTACACTGGGGCTCTCTGAGCTTTGGGACACAGGACACTGCCAGGGCTACGTAGGGAAC
TGACTCAGAAGACGCAGCTTACTGCTTCCAACTTTGCACATCTTCCTCTTTAAAAAACTGAGAAAATGCAAAAACTGGAACTTTTTGCAA
TATTATAAAAGAAGTAATCTTATTTTAGCTCATTCTGTGACATGTGCGACTCTTAAGAAAGCCATACTTAATGGTGGTGGTTTTTTTTAG
ATCTTATATTGTGTTTTGTATGCAGCCCTTTTAGAACTACTTGTAGTGAGGGTGCTGTGTGTGCTTTTCTTAAATATTTATTTTTTTCAA
CATGCTTTCAACCTGTCAACAAAAACAAAACACACAAAAAAAGGGCAGTGTTTGAAGATTGTTGATTTTTTTCTGGGGATAATCTATATT
ATATTGACTTCCTATTACTTATTATAAACCTGTGTTTGTATTGGAGATGTGTCTACTATTGGGGGAAGAGGTTCTCGTAATCGCTCGGTG
GGAAATCATGGCTCTGCCGTCCTGCCTCTCTGTGGCCGTGGGTTCACGTGGCCTCTGCGGTGAGTCTCCAAGTTTCTGCCTAGGCGCCTG

>96582_96582_3_UCKL1-ZBTB46_UCKL1_chr20_62575750_ENST00000369892_ZBTB46_chr20_62378654_ENST00000245663_length(amino acids)=435AA_BP=1
MCPPPTHFMSGPRAPLLLGSHLLSPQGWFPWGVGSGGSRGGAARGVSVALAPQWRPTGHTHGWTERGSHRPCRRAGLGEPGEVLVRASWG
AARPRRVFLILVVRQQRILRGQALVVLAQLLRLPSWVLRVLQIGPVAWEQRLWRALAASAAMVQGPGHAAASTVGAHTVAPGAMPDAHAG
GGHEDAAAHLAHILLVLAVDLLQLAVHVLHNQVDGHRVAAPSGDHDVCQAHGGLDVLVEGGLDKLVVLLDDTLDVPAALTDVPAQPPYQA
DVGVCVHKDLHVQELQQCLVSKGHDALKDDDVCTIQCFPVLLPAVRGEVINGHLDTLPLLQLLEGGNDEVEVKGIWVVEVEVVVCGLFLL

--------------------------------------------------------------
>96582_96582_4_UCKL1-ZBTB46_UCKL1_chr20_62575750_ENST00000369908_ZBTB46_chr20_62378654_ENST00000245663_length(transcript)=4797nt_BP=1161nt
AGTACGGTGGAGGCTTCAAGGGCCTCCTAGCTGCTGTGCCTCTGCTGACATTTGGCAGGCAGCTTCTGCCAGCCAAGGGTCTCACCCCAG
CCACCCGGCTCTGCACCCACTGTGCTGCCCACAGGAGTGGTCCTGCCCATGGAAGGGCCAGTTCAGGTGGCCGGAGCTCCTGAGCTGCCC
TAGGGGACTGCTGTGGGTCTGAGGTGGTGATGTCCCCCACGGCTGCCTGCGCCTGAGCCCCCACGCATCCACCCCTGGGGCCACTCTGCT
GTTCAGGAGCACCCACCCGTGTCCTCGACCATGAGCAGCCCCCCAGCTTACCCTGGCATCAGGATCTCAGGGTGCCGGGCCCTTGGAGCA
GAAGGCAGCAGCAATGCAGAGTCCCTGGACAGGCTCCTGCCACCTGTGGGCACTGGGCGCTCTCCCCGGAAGCGGACCACCAGCCAGTGC
AAGTCAGAGCCTCCCCTGCTGCGTACAAGCAAGCGTACCATCTACACCGCCGGGCGGCCGCCCTGGTACAATGAACACGGCACGCAATCC
AAAGAGGCCTTCGCCATCGGCTTGGGAGGCGGCAGTGCCTCTGGGAAGACCACTGTGGCCAGAATGATCATCGAGGCCCTGGATGTGCCC
TGGGTGGTCTTGCTGTCCATGGACTCCTTCTACAAGGTGCTGACTGAGCAGCAGCAGGAACAGGCCGCACACAACAACTTCAACTTCGAC
CACCCAGATGCCTTTGACTTCGACCTCATCATTTCCACCCTCAAGAAGCTGAAGCAGGGGAAGAGTGTCAAGGTGCCCATTTATGACTTC
ACCACGCACAGCCGGAAGAAGGACTGGAAAACACTGTATGGTGCAAACGTCATCATCTTTGAGGGCATCATGGCCTTTGCTGACAAGACA
CTGTTGGAGCTCCTGGACATGAAGATCTTTGTGGACACAGACTCCGACATCCGCCTGGTACGGCGGCTGCGCCGGGACATCAGTGAGCGC
GGCCGGGACATCGAGGGTGTCATCAAGCAGTACAACAAGTTTGTCAAGCCCTCCTTCGACCAGTACATCCAGCCCACCATGCGCCTGGCA
GACATCGTGGTCCCCAGAGGGAGCGGCAACACGGTGGCCATCGACCTGATTGTGCAGCACGTGCACAGCCAGCTGGAGGAGGTCCACAGC
AAGGACAAGAAGTATGTGTGCAAGGTGTGCAGCCGCGTCTTCATGTCCGCCGCCAGCGTGGGCATCAGGCATGGCTCCAGGCGCCACGGT
GTGTGCACCGACTGTGCTGGCCGCGGCATGGCCGGGCCCCTGGACCATGGCGGCGGAGGCGGCGAGGGCTCTCCAGAGGCGCTGTTCCCA
GGCGACGGGCCCTATCTGGAGGACCCTGAGGACCCACGAGGGGAGGCGGAGGAGCTGGGCGAGGACGACGAGGGCCTGGCCCCTGAGGAT
GCGCTGTTGGCGGACGACAAGGATGAGGAAGACTCGCCGCGGCCGCGCAGCCCCCCAGGAGGCCCTGACAAGGACTTCGCCTGGCTCTCC
TAGGCCCGCCCGCCGGCAGGGTCGGTGGCTGCCTCGCTCCGTCCACCCGTGTGTGTGTCCGGTGGGTCTCCACTGCGGGGCCAGGGCCAC
GCTCACCCCTCTCGCGGCCCCTCCTCTGCTTCCCCCTGAACCCACCCCCCACGGAAACCAGCCCTGCGGGCTAAGCAGGTGCGACCCCAG
CAAGAGGGGTGCTCTGGGACCAGACATGAAGTGAGTTGGGGGAGGGCACAGGGTGGGTTTGAGTGAAGGGAGAGCACGGTCCTAAGTCCC
CAGCAGGTGGTGCGGGTGTGTGAGTGGCCCCTGTGATGGCCAGCCTGGCTTGGACACGTGATGGGCCTGTGGCCGGGTCCAGTGGGCACT
GGGCGGGGTGGTGTGTTCGGCCCAGAGGCCCCTGGCCTGAGCAGGTGCAGAGTTTTACAGACACCCGGTCAGCCCGGCTGGAGCCCGCCC
TCCCCTCCCCTAGCAGCCAGGTCACTGCCTGTGGCTGCAGCCGTGGCCCGTGGTGCAGCCGTGGCCCATGGCAGCCTGTAGAATCCAGGT
GCACAGAGAGCCCTGCCACCGTCTTACCTCTGGGCTTTGGTGCTTAACACACAACACAGCTGCAGACCCTGCTGGAGGCCGAGGGCTCCA
GGTGCTATCTTAGGTGGACACAGCCCTGGGGGCTCCTTCCAGGAGGGGACCCTCAGCCCTGTGCCCCCCACCACTTCAGGCCACACCAGG
TTCCCTCTGCAAGGGCCTCGGCTCAGTCGTGTGCACTTCCTCGGAGAGCCTTGGGCTGCCACGTCCACCCCGGGCTCTGCCCGTCCTGTT
CTGCCCATGGCCCAGCCCGGCCGCTCCTGCTGACCCCTCCTGGACGGGCTGGAGCTGGGCTCCTGCCTTTGCTGCTAACACTGGAGGCGG
TGTTCCTAACTGCAGTGTGCTGCTTACACCTCCCCGCGTGGGTAACCAAATTTTTAAGTAGTCAGAGACATATCGAGGTAGTTACATAAA
ATTATTTTGTTTGGCATTATTTTTCTCACTCGAAGAAACTATATAGGGTTGTTTTTCCTTTAGCTTGTGCTCAAGTCCTCTTGCTGTGTT
TTCAGAAGCACTCACATGTTCTTTCTTTTCCTGAGTGAAAAGCAAAGGTCCCACGGTGTGTGCTGTGGTGCACCGCCTGGCTTTGGGGGT
CCCGGAGGCAGGCTGCCTAGACTCACAGCCTCGGGACCGTTGCCACGGCCTGTCTTCTCGTTCAGGCCTGCCTCTGACAGCACTCACCAT
GAGGACATTCCATCCTTCACCCCCTCCTCTGGCACAGGCCACCACTGCGGTGCTGTGCCTTCAGATGGGAGGTGGGCGCGGTGGCCTCCT
CCTTCCCTCCAGGACCTGCCCGTGTGAAGACCCCCCGGAGTGCTGAGCTTCAGGGCTGCGTGGAAAGAGTTTTTACTCTCTTTTTCTAGC
CTGTATACCAGGCTTTTCCCCACATTGTCAGGTAGAGCACCAGCTTCCCTGACCGCTGCTGCTCGGGGAGGGCTGGGGCTGGCCGGGGGT
CCTGTGGAGGAGTACATGGAGGACTCCAGGTACAGCGCAGGAGTCACGGCTTTTGTTTTTTGACATTGGCCCCCGGTTCTACCAATGACA
GGGTGCCCTGGCTGGAGCTGTCATCACACACACCCCTCAGCTCGGAGGCTGTGGGCTCCTCAAAGCTGGAGAAAGAGGCCAAGATTTTTC
TGCACACGGAGTGTGGGGATAGGAGCCGGGCCAAGCGCTGGCCCCTCAGCGGTGAGCCCTGCCCACTCTTACCGAGCAAGGTGGGTGGCT
CTGGCACGAGTCCCCCAGGGGGAGAGCATGGCTACCAGGGAGCTGCAGCGGAGCCCTCCAGCCCTCACCCCAGGCCAGCCCCACCCCGGC
CTCTTTGAGAATTCTCAGAACTTTGTACCTTTCCCCTGATTTTTAAACCCTTTTTCTAAACAGACTGACTTTCTTACAAAATGCATTTGG
AAACCAGACCTTTGCTACCCACCAATGTCTCTGGGTTTTGTACCAGTCCCTGCTCTCAGGCCACCCTGCCCAGGACCCAGGCCCGCCTCC
CCCTCCACACTCAGGATGTCCTGCTCCATCTGGCCGGCTCACTCCGTGTGGCCTGCCTTTGCTGACCGTTTTGGGGTTCCCCGCCGGAGC
TACAGGGGCATTTTCTTCCCTAAAACCAACAGTGTCCCACTGACCTCCCCAAGTGTTTGCTGCGTGGCAGATTTCCTGTTCTTGTTCGCA
GTTTGCCGACTGAAGAGTGTGGGATTTCCGAGGCCCAGGTGAGCACGTCCATCTCAGGAGGCGTGGAGGGAAAAGACATGTCATGAAGGG
TTTTTTTTATGTGACTGATTTTTTTTTAAATCGATGTTCAAACTAATAAATATTTTTTTATGAAGAGGAAAAATGTGTAGATTACATTTC
ACATTTTGTATTTTTGTTTGTGTCTGTTTGTATTTTGGTGTTTACAACACCAAAGTGGGAAATACAGTCCATTGGGGATGGTGTTATTTG
GGGGCGGGGAGGGGGCAGGGACACCACGATTTTTCTGTCAAGCTCTGGATCCTGACCAGGTTGTACACTGGGGCTCTCTGAGCTTTGGGA
CACAGGACACTGCCAGGGCTACGTAGGGAACTGACTCAGAAGACGCAGCTTACTGCTTCCAACTTTGCACATCTTCCTCTTTAAAAAACT
GAGAAAATGCAAAAACTGGAACTTTTTGCAATATTATAAAAGAAGTAATCTTATTTTAGCTCATTCTGTGACATGTGCGACTCTTAAGAA
AGCCATACTTAATGGTGGTGGTTTTTTTTAGATCTTATATTGTGTTTTGTATGCAGCCCTTTTAGAACTACTTGTAGTGAGGGTGCTGTG
TGTGCTTTTCTTAAATATTTATTTTTTTCAACATGCTTTCAACCTGTCAACAAAAACAAAACACACAAAAAAAGGGCAGTGTTTGAAGAT
TGTTGATTTTTTTCTGGGGATAATCTATATTATATTGACTTCCTATTACTTATTATAAACCTGTGTTTGTATTGGAGATGTGTCTACTAT
TGGGGGAAGAGGTTCTCGTAATCGCTCGGTGGGAAATCATGGCTCTGCCGTCCTGCCTCTCTGTGGCCGTGGGTTCACGTGGCCTCTGCG
GTGAGTCTCCAAGTTTCTGCCTAGGCGCCTGTGCGTTTCCTTTCTGTGACGGGATTAGCTTAGACATCCTTGCAAAGCGATCACTTTCAA

>96582_96582_4_UCKL1-ZBTB46_UCKL1_chr20_62575750_ENST00000369908_ZBTB46_chr20_62378654_ENST00000245663_length(amino acids)=436AA_BP=1
MPAPEPPRIHPWGHSAVQEHPPVSSTMSSPPAYPGIRISGCRALGAEGSSNAESLDRLLPPVGTGRSPRKRTTSQCKSEPPLLRTSKRTI
YTAGRPPWYNEHGTQSKEAFAIGLGGGSASGKTTVARMIIEALDVPWVVLLSMDSFYKVLTEQQQEQAAHNNFNFDHPDAFDFDLIISTL
KKLKQGKSVKVPIYDFTTHSRKKDWKTLYGANVIIFEGIMAFADKTLLELLDMKIFVDTDSDIRLVRRLRRDISERGRDIEGVIKQYNKF
VKPSFDQYIQPTMRLADIVVPRGSGNTVAIDLIVQHVHSQLEEVHSKDKKYVCKVCSRVFMSAASVGIRHGSRRHGVCTDCAGRGMAGPL

--------------------------------------------------------------

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Fusion Gene PPI Analysis for UCKL1-ZBTB46


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for UCKL1-ZBTB46


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for UCKL1-ZBTB46


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource