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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:UNC45A-IQGAP1 (FusionGDB2 ID:96825)

Fusion Gene Summary for UNC45A-IQGAP1

check button Fusion gene summary
Fusion gene informationFusion gene name: UNC45A-IQGAP1
Fusion gene ID: 96825
HgeneTgene
Gene symbol

UNC45A

IQGAP1

Gene ID

55898

8826

Gene nameunc-45 myosin chaperone AIQ motif containing GTPase activating protein 1
SynonymsGC-UNC45|GCUNC-45|GCUNC45|IRO039700|SMAP-1|SMAP1|UNC-45AHUMORFA01|SAR1|p195
Cytomap

15q26.1

15q26.1

Type of geneprotein-codingprotein-coding
Descriptionprotein unc-45 homolog Ageneral cell UNC45smooth muscle cell associated protein-1unc-45 homolog Aras GTPase-activating-like protein IQGAP1RasGAP-like with IQ motifs
Modification date2020031320200327
UniProtAcc.

P46940

Ensembl transtripts involved in fusion geneENST00000553671, ENST00000394275, 
ENST00000418476, 		ENST00000268182, 
ENST00000560738, ENST00000560020, 
Fusion gene scores* DoF score6 X 3 X 6=10817 X 15 X 7=1785
# samples 919
** MAII scorelog2(9/108*10)=-0.263034405833794
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(19/1785*10)=-3.23185275058551
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: UNC45A [Title/Abstract] AND IQGAP1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointUNC45A(91483703)-IQGAP1(91029262), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneIQGAP1

GO:0071277

cellular response to calcium ion

18567582


check buttonFusion gene breakpoints across UNC45A (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across IQGAP1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-24-2023-01AUNC45Achr15

91483703

-IQGAP1chr15

91029262

+
ChimerDB4OVTCGA-24-2023-01AUNC45Achr15

91483703

+IQGAP1chr15

91029262

+
ChimerDB4OVTCGA-24-2023UNC45Achr15

91483703

+IQGAP1chr15

91029261

+
ChimerDB4READTCGA-AG-A036UNC45Achr15

91483703

+IQGAP1chr15

91029261

+


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Fusion Gene ORF analysis for UNC45A-IQGAP1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000553671ENST00000268182UNC45Achr15

91483703

+IQGAP1chr15

91029262

+
3UTR-3CDSENST00000553671ENST00000268182UNC45Achr15

91483703

+IQGAP1chr15

91029261

+
3UTR-3CDSENST00000553671ENST00000560738UNC45Achr15

91483703

+IQGAP1chr15

91029262

+
3UTR-3CDSENST00000553671ENST00000560738UNC45Achr15

91483703

+IQGAP1chr15

91029261

+
3UTR-intronENST00000553671ENST00000560020UNC45Achr15

91483703

+IQGAP1chr15

91029262

+
3UTR-intronENST00000553671ENST00000560020UNC45Achr15

91483703

+IQGAP1chr15

91029261

+
5CDS-intronENST00000394275ENST00000560020UNC45Achr15

91483703

+IQGAP1chr15

91029262

+
5CDS-intronENST00000394275ENST00000560020UNC45Achr15

91483703

+IQGAP1chr15

91029261

+
5CDS-intronENST00000418476ENST00000560020UNC45Achr15

91483703

+IQGAP1chr15

91029262

+
5CDS-intronENST00000418476ENST00000560020UNC45Achr15

91483703

+IQGAP1chr15

91029261

+
In-frameENST00000394275ENST00000268182UNC45Achr15

91483703

+IQGAP1chr15

91029262

+
In-frameENST00000394275ENST00000268182UNC45Achr15

91483703

+IQGAP1chr15

91029261

+
In-frameENST00000394275ENST00000560738UNC45Achr15

91483703

+IQGAP1chr15

91029262

+
In-frameENST00000394275ENST00000560738UNC45Achr15

91483703

+IQGAP1chr15

91029261

+
In-frameENST00000418476ENST00000268182UNC45Achr15

91483703

+IQGAP1chr15

91029262

+
In-frameENST00000418476ENST00000268182UNC45Achr15

91483703

+IQGAP1chr15

91029261

+
In-frameENST00000418476ENST00000560738UNC45Achr15

91483703

+IQGAP1chr15

91029262

+
In-frameENST00000418476ENST00000560738UNC45Achr15

91483703

+IQGAP1chr15

91029261

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000394275UNC45Achr1591483703+ENST00000268182IQGAP1chr1591029262+466514777572529590
ENST00000394275UNC45Achr1591483703+ENST00000560738IQGAP1chr1591029262+279314777572529590
ENST00000418476UNC45Achr1591483703+ENST00000268182IQGAP1chr1591029262+3915727401779579
ENST00000418476UNC45Achr1591483703+ENST00000560738IQGAP1chr1591029262+2043727401779579
ENST00000394275UNC45Achr1591483703+ENST00000268182IQGAP1chr1591029261+466514777572529590
ENST00000394275UNC45Achr1591483703+ENST00000560738IQGAP1chr1591029261+279314777572529590
ENST00000418476UNC45Achr1591483703+ENST00000268182IQGAP1chr1591029261+3915727401779579
ENST00000418476UNC45Achr1591483703+ENST00000560738IQGAP1chr1591029261+2043727401779579

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000394275ENST00000268182UNC45Achr1591483703+IQGAP1chr1591029262+0.0008883350.9991116
ENST00000394275ENST00000560738UNC45Achr1591483703+IQGAP1chr1591029262+0.0049671710.9950328
ENST00000418476ENST00000268182UNC45Achr1591483703+IQGAP1chr1591029262+0.0007256690.9992743
ENST00000418476ENST00000560738UNC45Achr1591483703+IQGAP1chr1591029262+0.0050500510.99494994
ENST00000394275ENST00000268182UNC45Achr1591483703+IQGAP1chr1591029261+0.0008883350.9991116
ENST00000394275ENST00000560738UNC45Achr1591483703+IQGAP1chr1591029261+0.0049671710.9950328
ENST00000418476ENST00000268182UNC45Achr1591483703+IQGAP1chr1591029261+0.0007256690.9992743
ENST00000418476ENST00000560738UNC45Achr1591483703+IQGAP1chr1591029261+0.0050500510.99494994

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Fusion Genomic Features for UNC45A-IQGAP1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
UNC45Achr1591483703+IQGAP1chr1591029261+1.94E-101
UNC45Achr1591483703+IQGAP1chr1591029261+1.94E-101
UNC45Achr1591483703+IQGAP1chr1591029261+1.94E-101
UNC45Achr1591483703+IQGAP1chr1591029261+1.94E-101

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for UNC45A-IQGAP1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr15:91483703/chr15:91029262)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.IQGAP1

P46940

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Plays a crucial role in regulating the dynamics and assembly of the actin cytoskeleton. Binds to activated CDC42 but does not stimulate its GTPase activity. It associates with calmodulin. Could serve as an assembly scaffold for the organization of a multimolecular complex that would interface incoming signals to the reorganization of the actin cytoskeleton at the plasma membrane. May promote neurite outgrowth (PubMed:15695813). May play a possible role in cell cycle regulation by contributing to cell cycle progression after DNA replication arrest (PubMed:20883816). {ECO:0000269|PubMed:15695813, ECO:0000269|PubMed:20883816}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneUNC45Achr15:91483703chr15:91029261ENST00000394275+92321_54214930.0RepeatNote=TPR 1
HgeneUNC45Achr15:91483703chr15:91029261ENST00000394275+92358_91214930.0RepeatNote=TPR 2
HgeneUNC45Achr15:91483703chr15:91029261ENST00000394275+92392_125214930.0RepeatNote=TPR 3
HgeneUNC45Achr15:91483703chr15:91029261ENST00000418476+62021_54229945.0RepeatNote=TPR 1
HgeneUNC45Achr15:91483703chr15:91029261ENST00000418476+62058_91229945.0RepeatNote=TPR 2
HgeneUNC45Achr15:91483703chr15:91029261ENST00000418476+62092_125229945.0RepeatNote=TPR 3
HgeneUNC45Achr15:91483703chr15:91029262ENST00000394275+92321_54214930.0RepeatNote=TPR 1
HgeneUNC45Achr15:91483703chr15:91029262ENST00000394275+92358_91214930.0RepeatNote=TPR 2
HgeneUNC45Achr15:91483703chr15:91029262ENST00000394275+92392_125214930.0RepeatNote=TPR 3
HgeneUNC45Achr15:91483703chr15:91029262ENST00000418476+62021_54229945.0RepeatNote=TPR 1
HgeneUNC45Achr15:91483703chr15:91029262ENST00000418476+62058_91229945.0RepeatNote=TPR 2
HgeneUNC45Achr15:91483703chr15:91029262ENST00000418476+62092_125229945.0RepeatNote=TPR 3

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneIQGAP1chr15:91483703chr15:91029261ENST0000026818229381004_123713071658.0DomainRas-GAP
TgeneIQGAP1chr15:91483703chr15:91029261ENST00000268182293844_15913071658.0DomainCalponin-homology (CH)
TgeneIQGAP1chr15:91483703chr15:91029261ENST000002681822938679_71213071658.0DomainWW
TgeneIQGAP1chr15:91483703chr15:91029261ENST000002681822938745_77413071658.0DomainIQ 1
TgeneIQGAP1chr15:91483703chr15:91029261ENST000002681822938775_80413071658.0DomainIQ 2
TgeneIQGAP1chr15:91483703chr15:91029261ENST000002681822938805_83413071658.0DomainIQ 3
TgeneIQGAP1chr15:91483703chr15:91029261ENST000002681822938835_86413071658.0DomainIQ 4
TgeneIQGAP1chr15:91483703chr15:91029262ENST0000026818229381004_123713071658.0DomainRas-GAP
TgeneIQGAP1chr15:91483703chr15:91029262ENST00000268182293844_15913071658.0DomainCalponin-homology (CH)
TgeneIQGAP1chr15:91483703chr15:91029262ENST000002681822938679_71213071658.0DomainWW
TgeneIQGAP1chr15:91483703chr15:91029262ENST000002681822938745_77413071658.0DomainIQ 1
TgeneIQGAP1chr15:91483703chr15:91029262ENST000002681822938775_80413071658.0DomainIQ 2
TgeneIQGAP1chr15:91483703chr15:91029262ENST000002681822938805_83413071658.0DomainIQ 3
TgeneIQGAP1chr15:91483703chr15:91029262ENST000002681822938835_86413071658.0DomainIQ 4
TgeneIQGAP1chr15:91483703chr15:91029261ENST0000026818229381276_165713071658.0RegionNote=C2
TgeneIQGAP1chr15:91483703chr15:91029261ENST000002681822938956_127413071658.0RegionNote=C1
TgeneIQGAP1chr15:91483703chr15:91029262ENST0000026818229381276_165713071658.0RegionNote=C2
TgeneIQGAP1chr15:91483703chr15:91029262ENST000002681822938956_127413071658.0RegionNote=C1


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Fusion Gene Sequence for UNC45A-IQGAP1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>96825_96825_1_UNC45A-IQGAP1_UNC45A_chr15_91483703_ENST00000394275_IQGAP1_chr15_91029261_ENST00000268182_length(transcript)=4665nt_BP=1477nt
ACTTAACAACCGAAGTAACCCGCAATGCGGAAGGGCGAGGGGATTGCGAGTCACCGAGTTTCCCGCGCGGCTTGAGTCACGGCCTAGAAA
GAGAGATGTTGGGGTTCCCAGGACCAGGACAGAGGTGGTAGTGAACTCTCATGGGCATCCAGAGAAGGTCAGGCCCCTTGCTGACAGGCC
TATCTGTGGGGCTACTGCTGCTCTTCAGCTGGGTGACCCTTGTCCAGCCAACCTCTCTCTCAGCTCTGGTCCACCACCCTCACTTGTGCC
AGACCACCCGGGATGTCCATGGCCGTCACTACCCTGGTTTCTTTTGCCCTCGTCTGTCTGATTCTCCAGAGGAAGCCTACTGCTGCCACC
TGCAGGCTGCAGGGGGCTCCTGCTGCACCCGGGCTGAATTTGAGGCCCTGTACCAAGTCAATCTGTCCGCTCTTCCGCCCCCGCCCATCC
TCAGGGGCCCAGGCCCGCTCCTAGTGCTGGGCCTCTACAACCTACTGGTTGTGACCCTGATGACCGTAGACCTCGTGCACTTCTGCTGCG
GTCGGGGCCGGAGTCTGGGCTGGAGCCACCGCAGGCCTCCCTCTGGGTCCTCCGCCGCGAGCTCCCTGCAGGTCTCTGCGGGGACAGCTT
AGGTGCGCCCGGAGCTTGCCTGCACCTGCGATCCAGAGCCAAGCGCCCCGCCCCTGCCCGGGCGCGCTCCCTCCTTAGCCCTGCCCCTCT
CTGACCCCACCTCCGACGCAAGAGTGGGGCGGGGCAGCTGCCGGTGGCGTCCCGAACCCAGACTCGCCCCGCCCCAGAGACTGCGCCTGC
GCGGGCACGAGACAACCTCTCCGCGATGACTGCCAGCTCAGTGGAGCAGCTGCGGAAGGAGGGCAATGAGCTGTTCAAATGTGGAGACTA
CGGGGGCGCCCTGGCGGCCTACACTCAGGCCCTGGGTCTGGACGCGACGCCCCAGGACCAGGCCGTTCTGCACCGGAACCGGGCCGCCTG
CCACCTCAAGCTGGAAGATTACGACAAAGCAGAAACAGAGGCATCCAAAGCCATTGAAAAGGATGGTGGGGATGTCAAAGCACTCTACCG
GCGGAGCCAAGCCCTAGAGAAGCTGGGCCGCCTGGACCAGGCTGTCCTTGACCTGCAGAGATGTGTGAGCTTGGAGCCCAAGAACAAAGT
TTTCCAGGAGGCCTTGCGGAACATCGGGGGCCAGATTCAGGAGAAGGTGCGATACATGTCCTCGACGGATGCCAAAGTGGAACAGATGTT
TCAGATACTGTTGGACCCAGAAGAGAAGGGCACTGAGAAAAAGCAAAAGGCTTCTCAGAACCTGGTGGTGCTGGCCAGGGAGGATGCTGG
AGCGGAGAAGATCTTCCGGAGTAATGGGGTTCAGCTCTTGCAACGTTTACTGGACATGGGAGAGACTGACCTCATGCTGGCGGCTCTGCG
TACGCTGGTTGGCATTTGCTCTGAGCATCAGTCACGGCTCCTGTTGGATCACCAGGATGCCATTGCTCCGGAGCACAATGATCCAATCCA
CGAACTGCTGGACGACCTCGGCGAGGTGCCCACCATCGAGTCCCTGATAGGGGAAAGCTCTGGCAATTTAAATGACCCAAATAAGGAGGC
ACTGGCTAAGACGGAAGTGTCTCTCACCCTGACCAACAAGTTCGACGTGCCTGGAGATGAGAATGCAGAAATGGATGCTCGAACCATCTT
ACTGAATACAAAACGTTTAATTGTGGATGTCATCCGGTTCCAGCCAGGAGAGACCTTGACTGAAATCCTAGAAACACCAGCCACCAGTGA
ACAGGAAGCAGAACATCAGAGAGCCATGCAGAGACGTGCTATCCGTGATGCCAAAACACCTGACAAGATGAAAAAGTCAAAATCTGTAAA
GGAAGACAGCAACCTCACTCTTCAAGAGAAGAAAGAGAAGATCCAGACAGGTTTAAAGAAGCTAACAGAGCTTGGAACCGTGGACCCAAA
GAACAAATACCAGGAACTGATCAACGACATTGCCAGGGATATTCGGAATCAGCGGAGGTACCGACAGAGGAGAAAGGCCGAACTAGTGAA
ACTGCAACAGACATACGCTGCTCTGAACTCTAAGGCCACCTTTTATGGGGAGCAGGTGGATTACTATAAAAGCTATATCAAAACCTGCTT
GGATAACTTAGCCAGCAAGGGCAAAGTCTCCAAAAAGCCTAGGGAAATGAAAGGAAAGAAAAGCAAAAAGATTTCTCTGAAATATACAGC
AGCAAGACTACATGAAAAAGGAGTTCTTCTGGAAATTGAGGACCTGCAAGTGAATCAGTTTAAAAATGTTATATTTGAAATCAGTCCAAC
AGAAGAAGTTGGAGACTTCGAAGTGAAAGCCAAATTCATGGGAGTTCAAATGGAGACTTTTATGTTACATTATCAGGACCTGCTGCAGCT
ACAGTATGAAGGAGTTGCAGTCATGAAATTATTTGATAGAGCTAAAGTAAATGTCAACCTCCTGATCTTCCTTCTCAACAAAAAGTTCTA
CGGGAAGTAATTGATCGTTTGCTGCCAGCCCAGAAGGATGAAGGAAAGAAGCACCTCACAGCTCCTTTCTAGGTCCTTCTTTCCTCATTG
GAAGCAAAGACCTAGCCAACAACAGCACCTCAATCTGATACACTCCCGATGCCACATTTTTAACTCCTCTCGCTCTGATGGGACATTTGT
TACCCTTTTTTCATAGTGAAATTGTGTTTCAGGCTTAGTCTGACCTTTCTGGTTTCTTCATTTTCTTCCATTACTTAGGAAAGAGTGGAA
ACTCCACTAAAATTTCTCTGTGTTGTTACAGTCTTAGAGGTTGCAGTACTATATTGTAAGCTTTGGTGTTTGTTTAATTAGCAATAGGGA
TGGTAGGATTCAAATGTGTGTCATTTAGAAGTGGAAGCTATTAGCACCAATGACATAAATACATACAAGACACACAACTAAAATGTCATG
TTATTAACAGTTATTAGGTTGTCATTTAAAAATAAAGTTCCTTTATATTTCTGTCCCATCAGGAAAACTGAAGGATATGGGGAATCATTG
GTTATCTTCCATTGTGTTTTTCTTTATGGACAGGAGCTAATGGAAGTGACAGTCATGTTCAAAGGAAGCATTTCTAGAAAAAAGGAGATA
ATGTTTTTAAATTTCATTATCAAACTTGGGCAATTCTGTTTGTGTAACTCCCCGACTAGTGGATGGGAGAGTCCCATTGCTAAAATTCAG
CTACTCAGATAAATTCAGAATGGGTCAAGGCACCTGCCTGTTTTTGTTGGTGCACAGAGATTGACTTGATTCAGAGAGACAATTCACTCC
ATCCCTATGGCAGAGGAATGGGTTAGCCCTAATGTAGAATGTCATTGTTTTTAAAACTGTTTTATATCTTAAGAGTGCCTTATTAAAGTA
TAGATGTATGTCTTAAAATGTGGGTGATAGGAATTTTAAAGATTTATATAATGCATCAAAAGCCTTAGAATAAGAAAAGCTTTTTTTAAA
TTGCTTTATCTGTATATCTGAACTCTTGAAACTTATAGCTAAAACACTAGGATTTATCTGCAGTGTTCAGGGAGATAATTCTGCCTTTAA
TTGTCTAAAACAAAAACAAAACCAGCCAACCTATGTTACACGTGAGATTAAAACCAATTTTTTCCCCATTTTTTCTCCTTTTTTCTCTTG
CTGCCCACATTGTGCCTTTATTTTATGAGCCCCAGTTTTCTGGGCTTAGTTTAAAAAAAAAATCAAGTCTAAACATTGCATTTAGAAAGC
TTTTGTTCTTGGATAAAAAGTCATACACTTTAAAAAAAAAAAAAACTTTTTCCAGGAAAATATATTGAAATCATGCTGCTGAGCCTCTAT
TTTCTTTCTTTGATGTTTTGATTCAGTATTCTTTTATCATAAATTTTTAGCATTTAAAAATTCACTGATGTACATTAAGCCAATAAACTG
CTTTAATGAATAACAAACTATGTAGTGTGTCCCTATTATAAATGCATTGGAGAAGTATTTTTATGAGACTCTTTACTCAGGTGCATGGTT
ACAGCCCACAGGGAGGCATGGAGTGCCATGGAAGGATTCGCCACTACCCAGACCTTGTTTTTTGTTGTATTTTGGAAGACAGGTTTTTTA
AAGAAACATTTTCCTCAGATTAAAAGATGATGCTATTACAACTAGCATTGCCTCAAAAACTGGGACCAACCAAAGTGTGTCAACCCTGTT
TCCTTAAAAGAGGCTATGAATCCCAAAGGCCACATCCAAGACAGGCAATAATGAGCAGAGTTTACAGCTCCTTTAATAAAATGTGTCAGT
AATTTTAAGGTTTATAGTTCCCTCAACACAATTGCTAATGCAGAATAGTGTAAAATGCGCTTCAAGAATGTTGATGATGATGATATAGAA
TTGTGGCTTTAGTAGCACAGAGGATGCCCCAACAAACTCATGGCGTTGAAACCACACAGTTCTCATTACTGTTATTTATTAGCTGTAGCA
TTCTCTGTCTCCTCTCTCTCCTCCTTTGACCTTCTCCTCGACCAGCCATCATGACATTTACCATGAATTTACTTCCTCCCAAGAGTTTGG

>96825_96825_1_UNC45A-IQGAP1_UNC45A_chr15_91483703_ENST00000394275_IQGAP1_chr15_91029261_ENST00000268182_length(amino acids)=590AA_BP=240
MPVASRTQTRPAPETAPARARDNLSAMTASSVEQLRKEGNELFKCGDYGGALAAYTQALGLDATPQDQAVLHRNRAACHLKLEDYDKAET
EASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRCVSLEPKNKVFQEALRNIGGQIQEKVRYMSSTDAKVEQMFQILLDPEEKGTE
KKQKASQNLVVLAREDAGAEKIFRSNGVQLLQRLLDMGETDLMLAALRTLVGICSEHQSRLLLDHQDAIAPEHNDPIHELLDDLGEVPTI
ESLIGESSGNLNDPNKEALAKTEVSLTLTNKFDVPGDENAEMDARTILLNTKRLIVDVIRFQPGETLTEILETPATSEQEAEHQRAMQRR
AIRDAKTPDKMKKSKSVKEDSNLTLQEKKEKIQTGLKKLTELGTVDPKNKYQELINDIARDIRNQRRYRQRRKAELVKLQQTYAALNSKA
TFYGEQVDYYKSYIKTCLDNLASKGKVSKKPREMKGKKSKKISLKYTAARLHEKGVLLEIEDLQVNQFKNVIFEISPTEEVGDFEVKAKF

--------------------------------------------------------------
>96825_96825_2_UNC45A-IQGAP1_UNC45A_chr15_91483703_ENST00000394275_IQGAP1_chr15_91029261_ENST00000560738_length(transcript)=2793nt_BP=1477nt
ACTTAACAACCGAAGTAACCCGCAATGCGGAAGGGCGAGGGGATTGCGAGTCACCGAGTTTCCCGCGCGGCTTGAGTCACGGCCTAGAAA
GAGAGATGTTGGGGTTCCCAGGACCAGGACAGAGGTGGTAGTGAACTCTCATGGGCATCCAGAGAAGGTCAGGCCCCTTGCTGACAGGCC
TATCTGTGGGGCTACTGCTGCTCTTCAGCTGGGTGACCCTTGTCCAGCCAACCTCTCTCTCAGCTCTGGTCCACCACCCTCACTTGTGCC
AGACCACCCGGGATGTCCATGGCCGTCACTACCCTGGTTTCTTTTGCCCTCGTCTGTCTGATTCTCCAGAGGAAGCCTACTGCTGCCACC
TGCAGGCTGCAGGGGGCTCCTGCTGCACCCGGGCTGAATTTGAGGCCCTGTACCAAGTCAATCTGTCCGCTCTTCCGCCCCCGCCCATCC
TCAGGGGCCCAGGCCCGCTCCTAGTGCTGGGCCTCTACAACCTACTGGTTGTGACCCTGATGACCGTAGACCTCGTGCACTTCTGCTGCG
GTCGGGGCCGGAGTCTGGGCTGGAGCCACCGCAGGCCTCCCTCTGGGTCCTCCGCCGCGAGCTCCCTGCAGGTCTCTGCGGGGACAGCTT
AGGTGCGCCCGGAGCTTGCCTGCACCTGCGATCCAGAGCCAAGCGCCCCGCCCCTGCCCGGGCGCGCTCCCTCCTTAGCCCTGCCCCTCT
CTGACCCCACCTCCGACGCAAGAGTGGGGCGGGGCAGCTGCCGGTGGCGTCCCGAACCCAGACTCGCCCCGCCCCAGAGACTGCGCCTGC
GCGGGCACGAGACAACCTCTCCGCGATGACTGCCAGCTCAGTGGAGCAGCTGCGGAAGGAGGGCAATGAGCTGTTCAAATGTGGAGACTA
CGGGGGCGCCCTGGCGGCCTACACTCAGGCCCTGGGTCTGGACGCGACGCCCCAGGACCAGGCCGTTCTGCACCGGAACCGGGCCGCCTG
CCACCTCAAGCTGGAAGATTACGACAAAGCAGAAACAGAGGCATCCAAAGCCATTGAAAAGGATGGTGGGGATGTCAAAGCACTCTACCG
GCGGAGCCAAGCCCTAGAGAAGCTGGGCCGCCTGGACCAGGCTGTCCTTGACCTGCAGAGATGTGTGAGCTTGGAGCCCAAGAACAAAGT
TTTCCAGGAGGCCTTGCGGAACATCGGGGGCCAGATTCAGGAGAAGGTGCGATACATGTCCTCGACGGATGCCAAAGTGGAACAGATGTT
TCAGATACTGTTGGACCCAGAAGAGAAGGGCACTGAGAAAAAGCAAAAGGCTTCTCAGAACCTGGTGGTGCTGGCCAGGGAGGATGCTGG
AGCGGAGAAGATCTTCCGGAGTAATGGGGTTCAGCTCTTGCAACGTTTACTGGACATGGGAGAGACTGACCTCATGCTGGCGGCTCTGCG
TACGCTGGTTGGCATTTGCTCTGAGCATCAGTCACGGCTCCTGTTGGATCACCAGGATGCCATTGCTCCGGAGCACAATGATCCAATCCA
CGAACTGCTGGACGACCTCGGCGAGGTGCCCACCATCGAGTCCCTGATAGGGGAAAGCTCTGGCAATTTAAATGACCCAAATAAGGAGGC
ACTGGCTAAGACGGAAGTGTCTCTCACCCTGACCAACAAGTTCGACGTGCCTGGAGATGAGAATGCAGAAATGGATGCTCGAACCATCTT
ACTGAATACAAAACGTTTAATTGTGGATGTCATCCGGTTCCAGCCAGGAGAGACCTTGACTGAAATCCTAGAAACACCAGCCACCAGTGA
ACAGGAAGCAGAACATCAGAGAGCCATGCAGAGACGTGCTATCCGTGATGCCAAAACACCTGACAAGATGAAAAAGTCAAAATCTGTAAA
GGAAGACAGCAACCTCACTCTTCAAGAGAAGAAAGAGAAGATCCAGACAGGTTTAAAGAAGCTAACAGAGCTTGGAACCGTGGACCCAAA
GAACAAATACCAGGAACTGATCAACGACATTGCCAGGGATATTCGGAATCAGCGGAGGTACCGACAGAGGAGAAAGGCCGAACTAGTGAA
ACTGCAACAGACATACGCTGCTCTGAACTCTAAGGCCACCTTTTATGGGGAGCAGGTGGATTACTATAAAAGCTATATCAAAACCTGCTT
GGATAACTTAGCCAGCAAGGGCAAAGTCTCCAAAAAGCCTAGGGAAATGAAAGGAAAGAAAAGCAAAAAGATTTCTCTGAAATATACAGC
AGCAAGACTACATGAAAAAGGAGTTCTTCTGGAAATTGAGGACCTGCAAGTGAATCAGTTTAAAAATGTTATATTTGAAATCAGTCCAAC
AGAAGAAGTTGGAGACTTCGAAGTGAAAGCCAAATTCATGGGAGTTCAAATGGAGACTTTTATGTTACATTATCAGGACCTGCTGCAGCT
ACAGTATGAAGGAGTTGCAGTCATGAAATTATTTGATAGAGCTAAAGTAAATGTCAACCTCCTGATCTTCCTTCTCAACAAAAAGTTCTA
CGGGAAGTAATTGATCGTTTGCTGCCAGCCCAGAAGGATGAAGGAAAGAAGCACCTCACAGCTCCTTTCTAGGTCCTTCTTTCCTCATTG
GAAGCAAAGACCTAGCCAACAACAGCACCTCAATCTGATACACTCCCGATGCCACATTTTTAACTCCTCTCGCTCTGATGGGACATTTGT
TACCCTTTTTTCATAGTGAAATTGTGTTTCAGGCTTAGTCTGACCTTTCTGGTTTCTTCATTTTCTTCCATTACTTAGGAAAGAGTGGAA

>96825_96825_2_UNC45A-IQGAP1_UNC45A_chr15_91483703_ENST00000394275_IQGAP1_chr15_91029261_ENST00000560738_length(amino acids)=590AA_BP=240
MPVASRTQTRPAPETAPARARDNLSAMTASSVEQLRKEGNELFKCGDYGGALAAYTQALGLDATPQDQAVLHRNRAACHLKLEDYDKAET
EASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRCVSLEPKNKVFQEALRNIGGQIQEKVRYMSSTDAKVEQMFQILLDPEEKGTE
KKQKASQNLVVLAREDAGAEKIFRSNGVQLLQRLLDMGETDLMLAALRTLVGICSEHQSRLLLDHQDAIAPEHNDPIHELLDDLGEVPTI
ESLIGESSGNLNDPNKEALAKTEVSLTLTNKFDVPGDENAEMDARTILLNTKRLIVDVIRFQPGETLTEILETPATSEQEAEHQRAMQRR
AIRDAKTPDKMKKSKSVKEDSNLTLQEKKEKIQTGLKKLTELGTVDPKNKYQELINDIARDIRNQRRYRQRRKAELVKLQQTYAALNSKA
TFYGEQVDYYKSYIKTCLDNLASKGKVSKKPREMKGKKSKKISLKYTAARLHEKGVLLEIEDLQVNQFKNVIFEISPTEEVGDFEVKAKF

--------------------------------------------------------------
>96825_96825_3_UNC45A-IQGAP1_UNC45A_chr15_91483703_ENST00000394275_IQGAP1_chr15_91029262_ENST00000268182_length(transcript)=4665nt_BP=1477nt
ACTTAACAACCGAAGTAACCCGCAATGCGGAAGGGCGAGGGGATTGCGAGTCACCGAGTTTCCCGCGCGGCTTGAGTCACGGCCTAGAAA
GAGAGATGTTGGGGTTCCCAGGACCAGGACAGAGGTGGTAGTGAACTCTCATGGGCATCCAGAGAAGGTCAGGCCCCTTGCTGACAGGCC
TATCTGTGGGGCTACTGCTGCTCTTCAGCTGGGTGACCCTTGTCCAGCCAACCTCTCTCTCAGCTCTGGTCCACCACCCTCACTTGTGCC
AGACCACCCGGGATGTCCATGGCCGTCACTACCCTGGTTTCTTTTGCCCTCGTCTGTCTGATTCTCCAGAGGAAGCCTACTGCTGCCACC
TGCAGGCTGCAGGGGGCTCCTGCTGCACCCGGGCTGAATTTGAGGCCCTGTACCAAGTCAATCTGTCCGCTCTTCCGCCCCCGCCCATCC
TCAGGGGCCCAGGCCCGCTCCTAGTGCTGGGCCTCTACAACCTACTGGTTGTGACCCTGATGACCGTAGACCTCGTGCACTTCTGCTGCG
GTCGGGGCCGGAGTCTGGGCTGGAGCCACCGCAGGCCTCCCTCTGGGTCCTCCGCCGCGAGCTCCCTGCAGGTCTCTGCGGGGACAGCTT
AGGTGCGCCCGGAGCTTGCCTGCACCTGCGATCCAGAGCCAAGCGCCCCGCCCCTGCCCGGGCGCGCTCCCTCCTTAGCCCTGCCCCTCT
CTGACCCCACCTCCGACGCAAGAGTGGGGCGGGGCAGCTGCCGGTGGCGTCCCGAACCCAGACTCGCCCCGCCCCAGAGACTGCGCCTGC
GCGGGCACGAGACAACCTCTCCGCGATGACTGCCAGCTCAGTGGAGCAGCTGCGGAAGGAGGGCAATGAGCTGTTCAAATGTGGAGACTA
CGGGGGCGCCCTGGCGGCCTACACTCAGGCCCTGGGTCTGGACGCGACGCCCCAGGACCAGGCCGTTCTGCACCGGAACCGGGCCGCCTG
CCACCTCAAGCTGGAAGATTACGACAAAGCAGAAACAGAGGCATCCAAAGCCATTGAAAAGGATGGTGGGGATGTCAAAGCACTCTACCG
GCGGAGCCAAGCCCTAGAGAAGCTGGGCCGCCTGGACCAGGCTGTCCTTGACCTGCAGAGATGTGTGAGCTTGGAGCCCAAGAACAAAGT
TTTCCAGGAGGCCTTGCGGAACATCGGGGGCCAGATTCAGGAGAAGGTGCGATACATGTCCTCGACGGATGCCAAAGTGGAACAGATGTT
TCAGATACTGTTGGACCCAGAAGAGAAGGGCACTGAGAAAAAGCAAAAGGCTTCTCAGAACCTGGTGGTGCTGGCCAGGGAGGATGCTGG
AGCGGAGAAGATCTTCCGGAGTAATGGGGTTCAGCTCTTGCAACGTTTACTGGACATGGGAGAGACTGACCTCATGCTGGCGGCTCTGCG
TACGCTGGTTGGCATTTGCTCTGAGCATCAGTCACGGCTCCTGTTGGATCACCAGGATGCCATTGCTCCGGAGCACAATGATCCAATCCA
CGAACTGCTGGACGACCTCGGCGAGGTGCCCACCATCGAGTCCCTGATAGGGGAAAGCTCTGGCAATTTAAATGACCCAAATAAGGAGGC
ACTGGCTAAGACGGAAGTGTCTCTCACCCTGACCAACAAGTTCGACGTGCCTGGAGATGAGAATGCAGAAATGGATGCTCGAACCATCTT
ACTGAATACAAAACGTTTAATTGTGGATGTCATCCGGTTCCAGCCAGGAGAGACCTTGACTGAAATCCTAGAAACACCAGCCACCAGTGA
ACAGGAAGCAGAACATCAGAGAGCCATGCAGAGACGTGCTATCCGTGATGCCAAAACACCTGACAAGATGAAAAAGTCAAAATCTGTAAA
GGAAGACAGCAACCTCACTCTTCAAGAGAAGAAAGAGAAGATCCAGACAGGTTTAAAGAAGCTAACAGAGCTTGGAACCGTGGACCCAAA
GAACAAATACCAGGAACTGATCAACGACATTGCCAGGGATATTCGGAATCAGCGGAGGTACCGACAGAGGAGAAAGGCCGAACTAGTGAA
ACTGCAACAGACATACGCTGCTCTGAACTCTAAGGCCACCTTTTATGGGGAGCAGGTGGATTACTATAAAAGCTATATCAAAACCTGCTT
GGATAACTTAGCCAGCAAGGGCAAAGTCTCCAAAAAGCCTAGGGAAATGAAAGGAAAGAAAAGCAAAAAGATTTCTCTGAAATATACAGC
AGCAAGACTACATGAAAAAGGAGTTCTTCTGGAAATTGAGGACCTGCAAGTGAATCAGTTTAAAAATGTTATATTTGAAATCAGTCCAAC
AGAAGAAGTTGGAGACTTCGAAGTGAAAGCCAAATTCATGGGAGTTCAAATGGAGACTTTTATGTTACATTATCAGGACCTGCTGCAGCT
ACAGTATGAAGGAGTTGCAGTCATGAAATTATTTGATAGAGCTAAAGTAAATGTCAACCTCCTGATCTTCCTTCTCAACAAAAAGTTCTA
CGGGAAGTAATTGATCGTTTGCTGCCAGCCCAGAAGGATGAAGGAAAGAAGCACCTCACAGCTCCTTTCTAGGTCCTTCTTTCCTCATTG
GAAGCAAAGACCTAGCCAACAACAGCACCTCAATCTGATACACTCCCGATGCCACATTTTTAACTCCTCTCGCTCTGATGGGACATTTGT
TACCCTTTTTTCATAGTGAAATTGTGTTTCAGGCTTAGTCTGACCTTTCTGGTTTCTTCATTTTCTTCCATTACTTAGGAAAGAGTGGAA
ACTCCACTAAAATTTCTCTGTGTTGTTACAGTCTTAGAGGTTGCAGTACTATATTGTAAGCTTTGGTGTTTGTTTAATTAGCAATAGGGA
TGGTAGGATTCAAATGTGTGTCATTTAGAAGTGGAAGCTATTAGCACCAATGACATAAATACATACAAGACACACAACTAAAATGTCATG
TTATTAACAGTTATTAGGTTGTCATTTAAAAATAAAGTTCCTTTATATTTCTGTCCCATCAGGAAAACTGAAGGATATGGGGAATCATTG
GTTATCTTCCATTGTGTTTTTCTTTATGGACAGGAGCTAATGGAAGTGACAGTCATGTTCAAAGGAAGCATTTCTAGAAAAAAGGAGATA
ATGTTTTTAAATTTCATTATCAAACTTGGGCAATTCTGTTTGTGTAACTCCCCGACTAGTGGATGGGAGAGTCCCATTGCTAAAATTCAG
CTACTCAGATAAATTCAGAATGGGTCAAGGCACCTGCCTGTTTTTGTTGGTGCACAGAGATTGACTTGATTCAGAGAGACAATTCACTCC
ATCCCTATGGCAGAGGAATGGGTTAGCCCTAATGTAGAATGTCATTGTTTTTAAAACTGTTTTATATCTTAAGAGTGCCTTATTAAAGTA
TAGATGTATGTCTTAAAATGTGGGTGATAGGAATTTTAAAGATTTATATAATGCATCAAAAGCCTTAGAATAAGAAAAGCTTTTTTTAAA
TTGCTTTATCTGTATATCTGAACTCTTGAAACTTATAGCTAAAACACTAGGATTTATCTGCAGTGTTCAGGGAGATAATTCTGCCTTTAA
TTGTCTAAAACAAAAACAAAACCAGCCAACCTATGTTACACGTGAGATTAAAACCAATTTTTTCCCCATTTTTTCTCCTTTTTTCTCTTG
CTGCCCACATTGTGCCTTTATTTTATGAGCCCCAGTTTTCTGGGCTTAGTTTAAAAAAAAAATCAAGTCTAAACATTGCATTTAGAAAGC
TTTTGTTCTTGGATAAAAAGTCATACACTTTAAAAAAAAAAAAAACTTTTTCCAGGAAAATATATTGAAATCATGCTGCTGAGCCTCTAT
TTTCTTTCTTTGATGTTTTGATTCAGTATTCTTTTATCATAAATTTTTAGCATTTAAAAATTCACTGATGTACATTAAGCCAATAAACTG
CTTTAATGAATAACAAACTATGTAGTGTGTCCCTATTATAAATGCATTGGAGAAGTATTTTTATGAGACTCTTTACTCAGGTGCATGGTT
ACAGCCCACAGGGAGGCATGGAGTGCCATGGAAGGATTCGCCACTACCCAGACCTTGTTTTTTGTTGTATTTTGGAAGACAGGTTTTTTA
AAGAAACATTTTCCTCAGATTAAAAGATGATGCTATTACAACTAGCATTGCCTCAAAAACTGGGACCAACCAAAGTGTGTCAACCCTGTT
TCCTTAAAAGAGGCTATGAATCCCAAAGGCCACATCCAAGACAGGCAATAATGAGCAGAGTTTACAGCTCCTTTAATAAAATGTGTCAGT
AATTTTAAGGTTTATAGTTCCCTCAACACAATTGCTAATGCAGAATAGTGTAAAATGCGCTTCAAGAATGTTGATGATGATGATATAGAA
TTGTGGCTTTAGTAGCACAGAGGATGCCCCAACAAACTCATGGCGTTGAAACCACACAGTTCTCATTACTGTTATTTATTAGCTGTAGCA
TTCTCTGTCTCCTCTCTCTCCTCCTTTGACCTTCTCCTCGACCAGCCATCATGACATTTACCATGAATTTACTTCCTCCCAAGAGTTTGG

>96825_96825_3_UNC45A-IQGAP1_UNC45A_chr15_91483703_ENST00000394275_IQGAP1_chr15_91029262_ENST00000268182_length(amino acids)=590AA_BP=240
MPVASRTQTRPAPETAPARARDNLSAMTASSVEQLRKEGNELFKCGDYGGALAAYTQALGLDATPQDQAVLHRNRAACHLKLEDYDKAET
EASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRCVSLEPKNKVFQEALRNIGGQIQEKVRYMSSTDAKVEQMFQILLDPEEKGTE
KKQKASQNLVVLAREDAGAEKIFRSNGVQLLQRLLDMGETDLMLAALRTLVGICSEHQSRLLLDHQDAIAPEHNDPIHELLDDLGEVPTI
ESLIGESSGNLNDPNKEALAKTEVSLTLTNKFDVPGDENAEMDARTILLNTKRLIVDVIRFQPGETLTEILETPATSEQEAEHQRAMQRR
AIRDAKTPDKMKKSKSVKEDSNLTLQEKKEKIQTGLKKLTELGTVDPKNKYQELINDIARDIRNQRRYRQRRKAELVKLQQTYAALNSKA
TFYGEQVDYYKSYIKTCLDNLASKGKVSKKPREMKGKKSKKISLKYTAARLHEKGVLLEIEDLQVNQFKNVIFEISPTEEVGDFEVKAKF

--------------------------------------------------------------
>96825_96825_4_UNC45A-IQGAP1_UNC45A_chr15_91483703_ENST00000394275_IQGAP1_chr15_91029262_ENST00000560738_length(transcript)=2793nt_BP=1477nt
ACTTAACAACCGAAGTAACCCGCAATGCGGAAGGGCGAGGGGATTGCGAGTCACCGAGTTTCCCGCGCGGCTTGAGTCACGGCCTAGAAA
GAGAGATGTTGGGGTTCCCAGGACCAGGACAGAGGTGGTAGTGAACTCTCATGGGCATCCAGAGAAGGTCAGGCCCCTTGCTGACAGGCC
TATCTGTGGGGCTACTGCTGCTCTTCAGCTGGGTGACCCTTGTCCAGCCAACCTCTCTCTCAGCTCTGGTCCACCACCCTCACTTGTGCC
AGACCACCCGGGATGTCCATGGCCGTCACTACCCTGGTTTCTTTTGCCCTCGTCTGTCTGATTCTCCAGAGGAAGCCTACTGCTGCCACC
TGCAGGCTGCAGGGGGCTCCTGCTGCACCCGGGCTGAATTTGAGGCCCTGTACCAAGTCAATCTGTCCGCTCTTCCGCCCCCGCCCATCC
TCAGGGGCCCAGGCCCGCTCCTAGTGCTGGGCCTCTACAACCTACTGGTTGTGACCCTGATGACCGTAGACCTCGTGCACTTCTGCTGCG
GTCGGGGCCGGAGTCTGGGCTGGAGCCACCGCAGGCCTCCCTCTGGGTCCTCCGCCGCGAGCTCCCTGCAGGTCTCTGCGGGGACAGCTT
AGGTGCGCCCGGAGCTTGCCTGCACCTGCGATCCAGAGCCAAGCGCCCCGCCCCTGCCCGGGCGCGCTCCCTCCTTAGCCCTGCCCCTCT
CTGACCCCACCTCCGACGCAAGAGTGGGGCGGGGCAGCTGCCGGTGGCGTCCCGAACCCAGACTCGCCCCGCCCCAGAGACTGCGCCTGC
GCGGGCACGAGACAACCTCTCCGCGATGACTGCCAGCTCAGTGGAGCAGCTGCGGAAGGAGGGCAATGAGCTGTTCAAATGTGGAGACTA
CGGGGGCGCCCTGGCGGCCTACACTCAGGCCCTGGGTCTGGACGCGACGCCCCAGGACCAGGCCGTTCTGCACCGGAACCGGGCCGCCTG
CCACCTCAAGCTGGAAGATTACGACAAAGCAGAAACAGAGGCATCCAAAGCCATTGAAAAGGATGGTGGGGATGTCAAAGCACTCTACCG
GCGGAGCCAAGCCCTAGAGAAGCTGGGCCGCCTGGACCAGGCTGTCCTTGACCTGCAGAGATGTGTGAGCTTGGAGCCCAAGAACAAAGT
TTTCCAGGAGGCCTTGCGGAACATCGGGGGCCAGATTCAGGAGAAGGTGCGATACATGTCCTCGACGGATGCCAAAGTGGAACAGATGTT
TCAGATACTGTTGGACCCAGAAGAGAAGGGCACTGAGAAAAAGCAAAAGGCTTCTCAGAACCTGGTGGTGCTGGCCAGGGAGGATGCTGG
AGCGGAGAAGATCTTCCGGAGTAATGGGGTTCAGCTCTTGCAACGTTTACTGGACATGGGAGAGACTGACCTCATGCTGGCGGCTCTGCG
TACGCTGGTTGGCATTTGCTCTGAGCATCAGTCACGGCTCCTGTTGGATCACCAGGATGCCATTGCTCCGGAGCACAATGATCCAATCCA
CGAACTGCTGGACGACCTCGGCGAGGTGCCCACCATCGAGTCCCTGATAGGGGAAAGCTCTGGCAATTTAAATGACCCAAATAAGGAGGC
ACTGGCTAAGACGGAAGTGTCTCTCACCCTGACCAACAAGTTCGACGTGCCTGGAGATGAGAATGCAGAAATGGATGCTCGAACCATCTT
ACTGAATACAAAACGTTTAATTGTGGATGTCATCCGGTTCCAGCCAGGAGAGACCTTGACTGAAATCCTAGAAACACCAGCCACCAGTGA
ACAGGAAGCAGAACATCAGAGAGCCATGCAGAGACGTGCTATCCGTGATGCCAAAACACCTGACAAGATGAAAAAGTCAAAATCTGTAAA
GGAAGACAGCAACCTCACTCTTCAAGAGAAGAAAGAGAAGATCCAGACAGGTTTAAAGAAGCTAACAGAGCTTGGAACCGTGGACCCAAA
GAACAAATACCAGGAACTGATCAACGACATTGCCAGGGATATTCGGAATCAGCGGAGGTACCGACAGAGGAGAAAGGCCGAACTAGTGAA
ACTGCAACAGACATACGCTGCTCTGAACTCTAAGGCCACCTTTTATGGGGAGCAGGTGGATTACTATAAAAGCTATATCAAAACCTGCTT
GGATAACTTAGCCAGCAAGGGCAAAGTCTCCAAAAAGCCTAGGGAAATGAAAGGAAAGAAAAGCAAAAAGATTTCTCTGAAATATACAGC
AGCAAGACTACATGAAAAAGGAGTTCTTCTGGAAATTGAGGACCTGCAAGTGAATCAGTTTAAAAATGTTATATTTGAAATCAGTCCAAC
AGAAGAAGTTGGAGACTTCGAAGTGAAAGCCAAATTCATGGGAGTTCAAATGGAGACTTTTATGTTACATTATCAGGACCTGCTGCAGCT
ACAGTATGAAGGAGTTGCAGTCATGAAATTATTTGATAGAGCTAAAGTAAATGTCAACCTCCTGATCTTCCTTCTCAACAAAAAGTTCTA
CGGGAAGTAATTGATCGTTTGCTGCCAGCCCAGAAGGATGAAGGAAAGAAGCACCTCACAGCTCCTTTCTAGGTCCTTCTTTCCTCATTG
GAAGCAAAGACCTAGCCAACAACAGCACCTCAATCTGATACACTCCCGATGCCACATTTTTAACTCCTCTCGCTCTGATGGGACATTTGT
TACCCTTTTTTCATAGTGAAATTGTGTTTCAGGCTTAGTCTGACCTTTCTGGTTTCTTCATTTTCTTCCATTACTTAGGAAAGAGTGGAA

>96825_96825_4_UNC45A-IQGAP1_UNC45A_chr15_91483703_ENST00000394275_IQGAP1_chr15_91029262_ENST00000560738_length(amino acids)=590AA_BP=240
MPVASRTQTRPAPETAPARARDNLSAMTASSVEQLRKEGNELFKCGDYGGALAAYTQALGLDATPQDQAVLHRNRAACHLKLEDYDKAET
EASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRCVSLEPKNKVFQEALRNIGGQIQEKVRYMSSTDAKVEQMFQILLDPEEKGTE
KKQKASQNLVVLAREDAGAEKIFRSNGVQLLQRLLDMGETDLMLAALRTLVGICSEHQSRLLLDHQDAIAPEHNDPIHELLDDLGEVPTI
ESLIGESSGNLNDPNKEALAKTEVSLTLTNKFDVPGDENAEMDARTILLNTKRLIVDVIRFQPGETLTEILETPATSEQEAEHQRAMQRR
AIRDAKTPDKMKKSKSVKEDSNLTLQEKKEKIQTGLKKLTELGTVDPKNKYQELINDIARDIRNQRRYRQRRKAELVKLQQTYAALNSKA
TFYGEQVDYYKSYIKTCLDNLASKGKVSKKPREMKGKKSKKISLKYTAARLHEKGVLLEIEDLQVNQFKNVIFEISPTEEVGDFEVKAKF

--------------------------------------------------------------
>96825_96825_5_UNC45A-IQGAP1_UNC45A_chr15_91483703_ENST00000418476_IQGAP1_chr15_91029261_ENST00000268182_length(transcript)=3915nt_BP=727nt
AGAGACTGCGCCTGCGCGGGCACGAGACAACCTCTCCGCGATGACTGTGAGTGGTCCAGGGACCCCCGAGCCCCGGCCGGCCACCCCCGG
GGCCAGCTCAGTGGAGCAGCTGCGGAAGGAGGGCAATGAGCTGTTCAAATGTGGAGACTACGGGGGCGCCCTGGCGGCCTACACTCAGGC
CCTGGGTCTGGACGCGACGCCCCAGGACCAGGCCGTTCTGCACCGGAACCGGGCCGCCTGCCACCTCAAGCTGGAAGATTACGACAAAGC
AGAAACAGAGGCATCCAAAGCCATTGAAAAGGATGGTGGGGATGTCAAAGCACTCTACCGGCGGAGCCAAGCCCTAGAGAAGCTGGGCCG
CCTGGACCAGGCTGTCCTTGACCTGCAGAGATGTGTGAGCTTGGAGCCCAAGAACAAAGTTTTCCAGGAGGCCTTGCGGAACATCGGGGG
CCAGATTCAGGAGAAGGTGCGATACATGTCCTCGACGGATGCCAAAGTGGAACAGATGTTTCAGATACTGTTGGACCCAGAAGAGAAGGG
CACTGAGAAAAAGCAAAAGGCTTCTCAGAACCTGGTGGTGCTGGCCAGGGAGGATGCTGGAGCGGAGAAGATCTTCCGGAGTAATGGGGT
TCAGCTCTTGCAACGTTTACTGGACATGGGAGAGACTGACCTCATGCTGGCGGCTCTGCGTACGCTGGTTGGCATTTGCTCTGAGCATCA
GTCACGGCTCCTGTTGGATCACCAGGATGCCATTGCTCCGGAGCACAATGATCCAATCCACGAACTGCTGGACGACCTCGGCGAGGTGCC
CACCATCGAGTCCCTGATAGGGGAAAGCTCTGGCAATTTAAATGACCCAAATAAGGAGGCACTGGCTAAGACGGAAGTGTCTCTCACCCT
GACCAACAAGTTCGACGTGCCTGGAGATGAGAATGCAGAAATGGATGCTCGAACCATCTTACTGAATACAAAACGTTTAATTGTGGATGT
CATCCGGTTCCAGCCAGGAGAGACCTTGACTGAAATCCTAGAAACACCAGCCACCAGTGAACAGGAAGCAGAACATCAGAGAGCCATGCA
GAGACGTGCTATCCGTGATGCCAAAACACCTGACAAGATGAAAAAGTCAAAATCTGTAAAGGAAGACAGCAACCTCACTCTTCAAGAGAA
GAAAGAGAAGATCCAGACAGGTTTAAAGAAGCTAACAGAGCTTGGAACCGTGGACCCAAAGAACAAATACCAGGAACTGATCAACGACAT
TGCCAGGGATATTCGGAATCAGCGGAGGTACCGACAGAGGAGAAAGGCCGAACTAGTGAAACTGCAACAGACATACGCTGCTCTGAACTC
TAAGGCCACCTTTTATGGGGAGCAGGTGGATTACTATAAAAGCTATATCAAAACCTGCTTGGATAACTTAGCCAGCAAGGGCAAAGTCTC
CAAAAAGCCTAGGGAAATGAAAGGAAAGAAAAGCAAAAAGATTTCTCTGAAATATACAGCAGCAAGACTACATGAAAAAGGAGTTCTTCT
GGAAATTGAGGACCTGCAAGTGAATCAGTTTAAAAATGTTATATTTGAAATCAGTCCAACAGAAGAAGTTGGAGACTTCGAAGTGAAAGC
CAAATTCATGGGAGTTCAAATGGAGACTTTTATGTTACATTATCAGGACCTGCTGCAGCTACAGTATGAAGGAGTTGCAGTCATGAAATT
ATTTGATAGAGCTAAAGTAAATGTCAACCTCCTGATCTTCCTTCTCAACAAAAAGTTCTACGGGAAGTAATTGATCGTTTGCTGCCAGCC
CAGAAGGATGAAGGAAAGAAGCACCTCACAGCTCCTTTCTAGGTCCTTCTTTCCTCATTGGAAGCAAAGACCTAGCCAACAACAGCACCT
CAATCTGATACACTCCCGATGCCACATTTTTAACTCCTCTCGCTCTGATGGGACATTTGTTACCCTTTTTTCATAGTGAAATTGTGTTTC
AGGCTTAGTCTGACCTTTCTGGTTTCTTCATTTTCTTCCATTACTTAGGAAAGAGTGGAAACTCCACTAAAATTTCTCTGTGTTGTTACA
GTCTTAGAGGTTGCAGTACTATATTGTAAGCTTTGGTGTTTGTTTAATTAGCAATAGGGATGGTAGGATTCAAATGTGTGTCATTTAGAA
GTGGAAGCTATTAGCACCAATGACATAAATACATACAAGACACACAACTAAAATGTCATGTTATTAACAGTTATTAGGTTGTCATTTAAA
AATAAAGTTCCTTTATATTTCTGTCCCATCAGGAAAACTGAAGGATATGGGGAATCATTGGTTATCTTCCATTGTGTTTTTCTTTATGGA
CAGGAGCTAATGGAAGTGACAGTCATGTTCAAAGGAAGCATTTCTAGAAAAAAGGAGATAATGTTTTTAAATTTCATTATCAAACTTGGG
CAATTCTGTTTGTGTAACTCCCCGACTAGTGGATGGGAGAGTCCCATTGCTAAAATTCAGCTACTCAGATAAATTCAGAATGGGTCAAGG
CACCTGCCTGTTTTTGTTGGTGCACAGAGATTGACTTGATTCAGAGAGACAATTCACTCCATCCCTATGGCAGAGGAATGGGTTAGCCCT
AATGTAGAATGTCATTGTTTTTAAAACTGTTTTATATCTTAAGAGTGCCTTATTAAAGTATAGATGTATGTCTTAAAATGTGGGTGATAG
GAATTTTAAAGATTTATATAATGCATCAAAAGCCTTAGAATAAGAAAAGCTTTTTTTAAATTGCTTTATCTGTATATCTGAACTCTTGAA
ACTTATAGCTAAAACACTAGGATTTATCTGCAGTGTTCAGGGAGATAATTCTGCCTTTAATTGTCTAAAACAAAAACAAAACCAGCCAAC
CTATGTTACACGTGAGATTAAAACCAATTTTTTCCCCATTTTTTCTCCTTTTTTCTCTTGCTGCCCACATTGTGCCTTTATTTTATGAGC
CCCAGTTTTCTGGGCTTAGTTTAAAAAAAAAATCAAGTCTAAACATTGCATTTAGAAAGCTTTTGTTCTTGGATAAAAAGTCATACACTT
TAAAAAAAAAAAAAACTTTTTCCAGGAAAATATATTGAAATCATGCTGCTGAGCCTCTATTTTCTTTCTTTGATGTTTTGATTCAGTATT
CTTTTATCATAAATTTTTAGCATTTAAAAATTCACTGATGTACATTAAGCCAATAAACTGCTTTAATGAATAACAAACTATGTAGTGTGT
CCCTATTATAAATGCATTGGAGAAGTATTTTTATGAGACTCTTTACTCAGGTGCATGGTTACAGCCCACAGGGAGGCATGGAGTGCCATG
GAAGGATTCGCCACTACCCAGACCTTGTTTTTTGTTGTATTTTGGAAGACAGGTTTTTTAAAGAAACATTTTCCTCAGATTAAAAGATGA
TGCTATTACAACTAGCATTGCCTCAAAAACTGGGACCAACCAAAGTGTGTCAACCCTGTTTCCTTAAAAGAGGCTATGAATCCCAAAGGC
CACATCCAAGACAGGCAATAATGAGCAGAGTTTACAGCTCCTTTAATAAAATGTGTCAGTAATTTTAAGGTTTATAGTTCCCTCAACACA
ATTGCTAATGCAGAATAGTGTAAAATGCGCTTCAAGAATGTTGATGATGATGATATAGAATTGTGGCTTTAGTAGCACAGAGGATGCCCC
AACAAACTCATGGCGTTGAAACCACACAGTTCTCATTACTGTTATTTATTAGCTGTAGCATTCTCTGTCTCCTCTCTCTCCTCCTTTGAC
CTTCTCCTCGACCAGCCATCATGACATTTACCATGAATTTACTTCCTCCCAAGAGTTTGGACTGCCCGTCAGATTGTTGCTGCACATAGT

>96825_96825_5_UNC45A-IQGAP1_UNC45A_chr15_91483703_ENST00000418476_IQGAP1_chr15_91029261_ENST00000268182_length(amino acids)=579AA_BP=229
MTVSGPGTPEPRPATPGASSVEQLRKEGNELFKCGDYGGALAAYTQALGLDATPQDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGG
DVKALYRRSQALEKLGRLDQAVLDLQRCVSLEPKNKVFQEALRNIGGQIQEKVRYMSSTDAKVEQMFQILLDPEEKGTEKKQKASQNLVV
LAREDAGAEKIFRSNGVQLLQRLLDMGETDLMLAALRTLVGICSEHQSRLLLDHQDAIAPEHNDPIHELLDDLGEVPTIESLIGESSGNL
NDPNKEALAKTEVSLTLTNKFDVPGDENAEMDARTILLNTKRLIVDVIRFQPGETLTEILETPATSEQEAEHQRAMQRRAIRDAKTPDKM
KKSKSVKEDSNLTLQEKKEKIQTGLKKLTELGTVDPKNKYQELINDIARDIRNQRRYRQRRKAELVKLQQTYAALNSKATFYGEQVDYYK
SYIKTCLDNLASKGKVSKKPREMKGKKSKKISLKYTAARLHEKGVLLEIEDLQVNQFKNVIFEISPTEEVGDFEVKAKFMGVQMETFMLH

--------------------------------------------------------------
>96825_96825_6_UNC45A-IQGAP1_UNC45A_chr15_91483703_ENST00000418476_IQGAP1_chr15_91029261_ENST00000560738_length(transcript)=2043nt_BP=727nt
AGAGACTGCGCCTGCGCGGGCACGAGACAACCTCTCCGCGATGACTGTGAGTGGTCCAGGGACCCCCGAGCCCCGGCCGGCCACCCCCGG
GGCCAGCTCAGTGGAGCAGCTGCGGAAGGAGGGCAATGAGCTGTTCAAATGTGGAGACTACGGGGGCGCCCTGGCGGCCTACACTCAGGC
CCTGGGTCTGGACGCGACGCCCCAGGACCAGGCCGTTCTGCACCGGAACCGGGCCGCCTGCCACCTCAAGCTGGAAGATTACGACAAAGC
AGAAACAGAGGCATCCAAAGCCATTGAAAAGGATGGTGGGGATGTCAAAGCACTCTACCGGCGGAGCCAAGCCCTAGAGAAGCTGGGCCG
CCTGGACCAGGCTGTCCTTGACCTGCAGAGATGTGTGAGCTTGGAGCCCAAGAACAAAGTTTTCCAGGAGGCCTTGCGGAACATCGGGGG
CCAGATTCAGGAGAAGGTGCGATACATGTCCTCGACGGATGCCAAAGTGGAACAGATGTTTCAGATACTGTTGGACCCAGAAGAGAAGGG
CACTGAGAAAAAGCAAAAGGCTTCTCAGAACCTGGTGGTGCTGGCCAGGGAGGATGCTGGAGCGGAGAAGATCTTCCGGAGTAATGGGGT
TCAGCTCTTGCAACGTTTACTGGACATGGGAGAGACTGACCTCATGCTGGCGGCTCTGCGTACGCTGGTTGGCATTTGCTCTGAGCATCA
GTCACGGCTCCTGTTGGATCACCAGGATGCCATTGCTCCGGAGCACAATGATCCAATCCACGAACTGCTGGACGACCTCGGCGAGGTGCC
CACCATCGAGTCCCTGATAGGGGAAAGCTCTGGCAATTTAAATGACCCAAATAAGGAGGCACTGGCTAAGACGGAAGTGTCTCTCACCCT
GACCAACAAGTTCGACGTGCCTGGAGATGAGAATGCAGAAATGGATGCTCGAACCATCTTACTGAATACAAAACGTTTAATTGTGGATGT
CATCCGGTTCCAGCCAGGAGAGACCTTGACTGAAATCCTAGAAACACCAGCCACCAGTGAACAGGAAGCAGAACATCAGAGAGCCATGCA
GAGACGTGCTATCCGTGATGCCAAAACACCTGACAAGATGAAAAAGTCAAAATCTGTAAAGGAAGACAGCAACCTCACTCTTCAAGAGAA
GAAAGAGAAGATCCAGACAGGTTTAAAGAAGCTAACAGAGCTTGGAACCGTGGACCCAAAGAACAAATACCAGGAACTGATCAACGACAT
TGCCAGGGATATTCGGAATCAGCGGAGGTACCGACAGAGGAGAAAGGCCGAACTAGTGAAACTGCAACAGACATACGCTGCTCTGAACTC
TAAGGCCACCTTTTATGGGGAGCAGGTGGATTACTATAAAAGCTATATCAAAACCTGCTTGGATAACTTAGCCAGCAAGGGCAAAGTCTC
CAAAAAGCCTAGGGAAATGAAAGGAAAGAAAAGCAAAAAGATTTCTCTGAAATATACAGCAGCAAGACTACATGAAAAAGGAGTTCTTCT
GGAAATTGAGGACCTGCAAGTGAATCAGTTTAAAAATGTTATATTTGAAATCAGTCCAACAGAAGAAGTTGGAGACTTCGAAGTGAAAGC
CAAATTCATGGGAGTTCAAATGGAGACTTTTATGTTACATTATCAGGACCTGCTGCAGCTACAGTATGAAGGAGTTGCAGTCATGAAATT
ATTTGATAGAGCTAAAGTAAATGTCAACCTCCTGATCTTCCTTCTCAACAAAAAGTTCTACGGGAAGTAATTGATCGTTTGCTGCCAGCC
CAGAAGGATGAAGGAAAGAAGCACCTCACAGCTCCTTTCTAGGTCCTTCTTTCCTCATTGGAAGCAAAGACCTAGCCAACAACAGCACCT
CAATCTGATACACTCCCGATGCCACATTTTTAACTCCTCTCGCTCTGATGGGACATTTGTTACCCTTTTTTCATAGTGAAATTGTGTTTC

>96825_96825_6_UNC45A-IQGAP1_UNC45A_chr15_91483703_ENST00000418476_IQGAP1_chr15_91029261_ENST00000560738_length(amino acids)=579AA_BP=229
MTVSGPGTPEPRPATPGASSVEQLRKEGNELFKCGDYGGALAAYTQALGLDATPQDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGG
DVKALYRRSQALEKLGRLDQAVLDLQRCVSLEPKNKVFQEALRNIGGQIQEKVRYMSSTDAKVEQMFQILLDPEEKGTEKKQKASQNLVV
LAREDAGAEKIFRSNGVQLLQRLLDMGETDLMLAALRTLVGICSEHQSRLLLDHQDAIAPEHNDPIHELLDDLGEVPTIESLIGESSGNL
NDPNKEALAKTEVSLTLTNKFDVPGDENAEMDARTILLNTKRLIVDVIRFQPGETLTEILETPATSEQEAEHQRAMQRRAIRDAKTPDKM
KKSKSVKEDSNLTLQEKKEKIQTGLKKLTELGTVDPKNKYQELINDIARDIRNQRRYRQRRKAELVKLQQTYAALNSKATFYGEQVDYYK
SYIKTCLDNLASKGKVSKKPREMKGKKSKKISLKYTAARLHEKGVLLEIEDLQVNQFKNVIFEISPTEEVGDFEVKAKFMGVQMETFMLH

--------------------------------------------------------------
>96825_96825_7_UNC45A-IQGAP1_UNC45A_chr15_91483703_ENST00000418476_IQGAP1_chr15_91029262_ENST00000268182_length(transcript)=3915nt_BP=727nt
AGAGACTGCGCCTGCGCGGGCACGAGACAACCTCTCCGCGATGACTGTGAGTGGTCCAGGGACCCCCGAGCCCCGGCCGGCCACCCCCGG
GGCCAGCTCAGTGGAGCAGCTGCGGAAGGAGGGCAATGAGCTGTTCAAATGTGGAGACTACGGGGGCGCCCTGGCGGCCTACACTCAGGC
CCTGGGTCTGGACGCGACGCCCCAGGACCAGGCCGTTCTGCACCGGAACCGGGCCGCCTGCCACCTCAAGCTGGAAGATTACGACAAAGC
AGAAACAGAGGCATCCAAAGCCATTGAAAAGGATGGTGGGGATGTCAAAGCACTCTACCGGCGGAGCCAAGCCCTAGAGAAGCTGGGCCG
CCTGGACCAGGCTGTCCTTGACCTGCAGAGATGTGTGAGCTTGGAGCCCAAGAACAAAGTTTTCCAGGAGGCCTTGCGGAACATCGGGGG
CCAGATTCAGGAGAAGGTGCGATACATGTCCTCGACGGATGCCAAAGTGGAACAGATGTTTCAGATACTGTTGGACCCAGAAGAGAAGGG
CACTGAGAAAAAGCAAAAGGCTTCTCAGAACCTGGTGGTGCTGGCCAGGGAGGATGCTGGAGCGGAGAAGATCTTCCGGAGTAATGGGGT
TCAGCTCTTGCAACGTTTACTGGACATGGGAGAGACTGACCTCATGCTGGCGGCTCTGCGTACGCTGGTTGGCATTTGCTCTGAGCATCA
GTCACGGCTCCTGTTGGATCACCAGGATGCCATTGCTCCGGAGCACAATGATCCAATCCACGAACTGCTGGACGACCTCGGCGAGGTGCC
CACCATCGAGTCCCTGATAGGGGAAAGCTCTGGCAATTTAAATGACCCAAATAAGGAGGCACTGGCTAAGACGGAAGTGTCTCTCACCCT
GACCAACAAGTTCGACGTGCCTGGAGATGAGAATGCAGAAATGGATGCTCGAACCATCTTACTGAATACAAAACGTTTAATTGTGGATGT
CATCCGGTTCCAGCCAGGAGAGACCTTGACTGAAATCCTAGAAACACCAGCCACCAGTGAACAGGAAGCAGAACATCAGAGAGCCATGCA
GAGACGTGCTATCCGTGATGCCAAAACACCTGACAAGATGAAAAAGTCAAAATCTGTAAAGGAAGACAGCAACCTCACTCTTCAAGAGAA
GAAAGAGAAGATCCAGACAGGTTTAAAGAAGCTAACAGAGCTTGGAACCGTGGACCCAAAGAACAAATACCAGGAACTGATCAACGACAT
TGCCAGGGATATTCGGAATCAGCGGAGGTACCGACAGAGGAGAAAGGCCGAACTAGTGAAACTGCAACAGACATACGCTGCTCTGAACTC
TAAGGCCACCTTTTATGGGGAGCAGGTGGATTACTATAAAAGCTATATCAAAACCTGCTTGGATAACTTAGCCAGCAAGGGCAAAGTCTC
CAAAAAGCCTAGGGAAATGAAAGGAAAGAAAAGCAAAAAGATTTCTCTGAAATATACAGCAGCAAGACTACATGAAAAAGGAGTTCTTCT
GGAAATTGAGGACCTGCAAGTGAATCAGTTTAAAAATGTTATATTTGAAATCAGTCCAACAGAAGAAGTTGGAGACTTCGAAGTGAAAGC
CAAATTCATGGGAGTTCAAATGGAGACTTTTATGTTACATTATCAGGACCTGCTGCAGCTACAGTATGAAGGAGTTGCAGTCATGAAATT
ATTTGATAGAGCTAAAGTAAATGTCAACCTCCTGATCTTCCTTCTCAACAAAAAGTTCTACGGGAAGTAATTGATCGTTTGCTGCCAGCC
CAGAAGGATGAAGGAAAGAAGCACCTCACAGCTCCTTTCTAGGTCCTTCTTTCCTCATTGGAAGCAAAGACCTAGCCAACAACAGCACCT
CAATCTGATACACTCCCGATGCCACATTTTTAACTCCTCTCGCTCTGATGGGACATTTGTTACCCTTTTTTCATAGTGAAATTGTGTTTC
AGGCTTAGTCTGACCTTTCTGGTTTCTTCATTTTCTTCCATTACTTAGGAAAGAGTGGAAACTCCACTAAAATTTCTCTGTGTTGTTACA
GTCTTAGAGGTTGCAGTACTATATTGTAAGCTTTGGTGTTTGTTTAATTAGCAATAGGGATGGTAGGATTCAAATGTGTGTCATTTAGAA
GTGGAAGCTATTAGCACCAATGACATAAATACATACAAGACACACAACTAAAATGTCATGTTATTAACAGTTATTAGGTTGTCATTTAAA
AATAAAGTTCCTTTATATTTCTGTCCCATCAGGAAAACTGAAGGATATGGGGAATCATTGGTTATCTTCCATTGTGTTTTTCTTTATGGA
CAGGAGCTAATGGAAGTGACAGTCATGTTCAAAGGAAGCATTTCTAGAAAAAAGGAGATAATGTTTTTAAATTTCATTATCAAACTTGGG
CAATTCTGTTTGTGTAACTCCCCGACTAGTGGATGGGAGAGTCCCATTGCTAAAATTCAGCTACTCAGATAAATTCAGAATGGGTCAAGG
CACCTGCCTGTTTTTGTTGGTGCACAGAGATTGACTTGATTCAGAGAGACAATTCACTCCATCCCTATGGCAGAGGAATGGGTTAGCCCT
AATGTAGAATGTCATTGTTTTTAAAACTGTTTTATATCTTAAGAGTGCCTTATTAAAGTATAGATGTATGTCTTAAAATGTGGGTGATAG
GAATTTTAAAGATTTATATAATGCATCAAAAGCCTTAGAATAAGAAAAGCTTTTTTTAAATTGCTTTATCTGTATATCTGAACTCTTGAA
ACTTATAGCTAAAACACTAGGATTTATCTGCAGTGTTCAGGGAGATAATTCTGCCTTTAATTGTCTAAAACAAAAACAAAACCAGCCAAC
CTATGTTACACGTGAGATTAAAACCAATTTTTTCCCCATTTTTTCTCCTTTTTTCTCTTGCTGCCCACATTGTGCCTTTATTTTATGAGC
CCCAGTTTTCTGGGCTTAGTTTAAAAAAAAAATCAAGTCTAAACATTGCATTTAGAAAGCTTTTGTTCTTGGATAAAAAGTCATACACTT
TAAAAAAAAAAAAAACTTTTTCCAGGAAAATATATTGAAATCATGCTGCTGAGCCTCTATTTTCTTTCTTTGATGTTTTGATTCAGTATT
CTTTTATCATAAATTTTTAGCATTTAAAAATTCACTGATGTACATTAAGCCAATAAACTGCTTTAATGAATAACAAACTATGTAGTGTGT
CCCTATTATAAATGCATTGGAGAAGTATTTTTATGAGACTCTTTACTCAGGTGCATGGTTACAGCCCACAGGGAGGCATGGAGTGCCATG
GAAGGATTCGCCACTACCCAGACCTTGTTTTTTGTTGTATTTTGGAAGACAGGTTTTTTAAAGAAACATTTTCCTCAGATTAAAAGATGA
TGCTATTACAACTAGCATTGCCTCAAAAACTGGGACCAACCAAAGTGTGTCAACCCTGTTTCCTTAAAAGAGGCTATGAATCCCAAAGGC
CACATCCAAGACAGGCAATAATGAGCAGAGTTTACAGCTCCTTTAATAAAATGTGTCAGTAATTTTAAGGTTTATAGTTCCCTCAACACA
ATTGCTAATGCAGAATAGTGTAAAATGCGCTTCAAGAATGTTGATGATGATGATATAGAATTGTGGCTTTAGTAGCACAGAGGATGCCCC
AACAAACTCATGGCGTTGAAACCACACAGTTCTCATTACTGTTATTTATTAGCTGTAGCATTCTCTGTCTCCTCTCTCTCCTCCTTTGAC
CTTCTCCTCGACCAGCCATCATGACATTTACCATGAATTTACTTCCTCCCAAGAGTTTGGACTGCCCGTCAGATTGTTGCTGCACATAGT

>96825_96825_7_UNC45A-IQGAP1_UNC45A_chr15_91483703_ENST00000418476_IQGAP1_chr15_91029262_ENST00000268182_length(amino acids)=579AA_BP=229
MTVSGPGTPEPRPATPGASSVEQLRKEGNELFKCGDYGGALAAYTQALGLDATPQDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGG
DVKALYRRSQALEKLGRLDQAVLDLQRCVSLEPKNKVFQEALRNIGGQIQEKVRYMSSTDAKVEQMFQILLDPEEKGTEKKQKASQNLVV
LAREDAGAEKIFRSNGVQLLQRLLDMGETDLMLAALRTLVGICSEHQSRLLLDHQDAIAPEHNDPIHELLDDLGEVPTIESLIGESSGNL
NDPNKEALAKTEVSLTLTNKFDVPGDENAEMDARTILLNTKRLIVDVIRFQPGETLTEILETPATSEQEAEHQRAMQRRAIRDAKTPDKM
KKSKSVKEDSNLTLQEKKEKIQTGLKKLTELGTVDPKNKYQELINDIARDIRNQRRYRQRRKAELVKLQQTYAALNSKATFYGEQVDYYK
SYIKTCLDNLASKGKVSKKPREMKGKKSKKISLKYTAARLHEKGVLLEIEDLQVNQFKNVIFEISPTEEVGDFEVKAKFMGVQMETFMLH

--------------------------------------------------------------
>96825_96825_8_UNC45A-IQGAP1_UNC45A_chr15_91483703_ENST00000418476_IQGAP1_chr15_91029262_ENST00000560738_length(transcript)=2043nt_BP=727nt
AGAGACTGCGCCTGCGCGGGCACGAGACAACCTCTCCGCGATGACTGTGAGTGGTCCAGGGACCCCCGAGCCCCGGCCGGCCACCCCCGG
GGCCAGCTCAGTGGAGCAGCTGCGGAAGGAGGGCAATGAGCTGTTCAAATGTGGAGACTACGGGGGCGCCCTGGCGGCCTACACTCAGGC
CCTGGGTCTGGACGCGACGCCCCAGGACCAGGCCGTTCTGCACCGGAACCGGGCCGCCTGCCACCTCAAGCTGGAAGATTACGACAAAGC
AGAAACAGAGGCATCCAAAGCCATTGAAAAGGATGGTGGGGATGTCAAAGCACTCTACCGGCGGAGCCAAGCCCTAGAGAAGCTGGGCCG
CCTGGACCAGGCTGTCCTTGACCTGCAGAGATGTGTGAGCTTGGAGCCCAAGAACAAAGTTTTCCAGGAGGCCTTGCGGAACATCGGGGG
CCAGATTCAGGAGAAGGTGCGATACATGTCCTCGACGGATGCCAAAGTGGAACAGATGTTTCAGATACTGTTGGACCCAGAAGAGAAGGG
CACTGAGAAAAAGCAAAAGGCTTCTCAGAACCTGGTGGTGCTGGCCAGGGAGGATGCTGGAGCGGAGAAGATCTTCCGGAGTAATGGGGT
TCAGCTCTTGCAACGTTTACTGGACATGGGAGAGACTGACCTCATGCTGGCGGCTCTGCGTACGCTGGTTGGCATTTGCTCTGAGCATCA
GTCACGGCTCCTGTTGGATCACCAGGATGCCATTGCTCCGGAGCACAATGATCCAATCCACGAACTGCTGGACGACCTCGGCGAGGTGCC
CACCATCGAGTCCCTGATAGGGGAAAGCTCTGGCAATTTAAATGACCCAAATAAGGAGGCACTGGCTAAGACGGAAGTGTCTCTCACCCT
GACCAACAAGTTCGACGTGCCTGGAGATGAGAATGCAGAAATGGATGCTCGAACCATCTTACTGAATACAAAACGTTTAATTGTGGATGT
CATCCGGTTCCAGCCAGGAGAGACCTTGACTGAAATCCTAGAAACACCAGCCACCAGTGAACAGGAAGCAGAACATCAGAGAGCCATGCA
GAGACGTGCTATCCGTGATGCCAAAACACCTGACAAGATGAAAAAGTCAAAATCTGTAAAGGAAGACAGCAACCTCACTCTTCAAGAGAA
GAAAGAGAAGATCCAGACAGGTTTAAAGAAGCTAACAGAGCTTGGAACCGTGGACCCAAAGAACAAATACCAGGAACTGATCAACGACAT
TGCCAGGGATATTCGGAATCAGCGGAGGTACCGACAGAGGAGAAAGGCCGAACTAGTGAAACTGCAACAGACATACGCTGCTCTGAACTC
TAAGGCCACCTTTTATGGGGAGCAGGTGGATTACTATAAAAGCTATATCAAAACCTGCTTGGATAACTTAGCCAGCAAGGGCAAAGTCTC
CAAAAAGCCTAGGGAAATGAAAGGAAAGAAAAGCAAAAAGATTTCTCTGAAATATACAGCAGCAAGACTACATGAAAAAGGAGTTCTTCT
GGAAATTGAGGACCTGCAAGTGAATCAGTTTAAAAATGTTATATTTGAAATCAGTCCAACAGAAGAAGTTGGAGACTTCGAAGTGAAAGC
CAAATTCATGGGAGTTCAAATGGAGACTTTTATGTTACATTATCAGGACCTGCTGCAGCTACAGTATGAAGGAGTTGCAGTCATGAAATT
ATTTGATAGAGCTAAAGTAAATGTCAACCTCCTGATCTTCCTTCTCAACAAAAAGTTCTACGGGAAGTAATTGATCGTTTGCTGCCAGCC
CAGAAGGATGAAGGAAAGAAGCACCTCACAGCTCCTTTCTAGGTCCTTCTTTCCTCATTGGAAGCAAAGACCTAGCCAACAACAGCACCT
CAATCTGATACACTCCCGATGCCACATTTTTAACTCCTCTCGCTCTGATGGGACATTTGTTACCCTTTTTTCATAGTGAAATTGTGTTTC

>96825_96825_8_UNC45A-IQGAP1_UNC45A_chr15_91483703_ENST00000418476_IQGAP1_chr15_91029262_ENST00000560738_length(amino acids)=579AA_BP=229
MTVSGPGTPEPRPATPGASSVEQLRKEGNELFKCGDYGGALAAYTQALGLDATPQDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGG
DVKALYRRSQALEKLGRLDQAVLDLQRCVSLEPKNKVFQEALRNIGGQIQEKVRYMSSTDAKVEQMFQILLDPEEKGTEKKQKASQNLVV
LAREDAGAEKIFRSNGVQLLQRLLDMGETDLMLAALRTLVGICSEHQSRLLLDHQDAIAPEHNDPIHELLDDLGEVPTIESLIGESSGNL
NDPNKEALAKTEVSLTLTNKFDVPGDENAEMDARTILLNTKRLIVDVIRFQPGETLTEILETPATSEQEAEHQRAMQRRAIRDAKTPDKM
KKSKSVKEDSNLTLQEKKEKIQTGLKKLTELGTVDPKNKYQELINDIARDIRNQRRYRQRRKAELVKLQQTYAALNSKATFYGEQVDYYK
SYIKTCLDNLASKGKVSKKPREMKGKKSKKISLKYTAARLHEKGVLLEIEDLQVNQFKNVIFEISPTEEVGDFEVKAKFMGVQMETFMLH

--------------------------------------------------------------

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Fusion Gene PPI Analysis for UNC45A-IQGAP1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for UNC45A-IQGAP1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for UNC45A-IQGAP1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource