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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:UNC45A-SV2B (FusionGDB2 ID:96829)

Fusion Gene Summary for UNC45A-SV2B

check button Fusion gene summary
Fusion gene informationFusion gene name: UNC45A-SV2B
Fusion gene ID: 96829
HgeneTgene
Gene symbol

UNC45A

SV2B

Gene ID

55898

9899

Gene nameunc-45 myosin chaperone Asynaptic vesicle glycoprotein 2B
SynonymsGC-UNC45|GCUNC-45|GCUNC45|IRO039700|SMAP-1|SMAP1|UNC-45AHsT19680
Cytomap

15q26.1

15q26.1

Type of geneprotein-codingprotein-coding
Descriptionprotein unc-45 homolog Ageneral cell UNC45smooth muscle cell associated protein-1unc-45 homolog Asynaptic vesicle glycoprotein 2Bsynaptic vesicle protein 2B homolog
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000394275, ENST00000418476, 
ENST00000553671, 		ENST00000330276, 
ENST00000557291, ENST00000394232, 
ENST00000545111, 
Fusion gene scores* DoF score6 X 3 X 6=1086 X 7 X 4=168
# samples 97
** MAII scorelog2(9/108*10)=-0.263034405833794
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(7/168*10)=-1.26303440583379
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: UNC45A [Title/Abstract] AND SV2B [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointUNC45A(91486312)-SV2B(91809812), # samples:2
Anticipated loss of major functional domain due to fusion event.UNC45A-SV2B seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across UNC45A (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across SV2B (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-BH-A0BP-01AUNC45Achr15

91486312

+SV2Bchr15

91809812

+


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Fusion Gene ORF analysis for UNC45A-SV2B

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000394275ENST00000330276UNC45Achr15

91486312

+SV2Bchr15

91809812

+
5CDS-intronENST00000394275ENST00000557291UNC45Achr15

91486312

+SV2Bchr15

91809812

+
5CDS-intronENST00000418476ENST00000330276UNC45Achr15

91486312

+SV2Bchr15

91809812

+
5CDS-intronENST00000418476ENST00000557291UNC45Achr15

91486312

+SV2Bchr15

91809812

+
5CDS-intronENST00000553671ENST00000330276UNC45Achr15

91486312

+SV2Bchr15

91809812

+
5CDS-intronENST00000553671ENST00000557291UNC45Achr15

91486312

+SV2Bchr15

91809812

+
Frame-shiftENST00000394275ENST00000394232UNC45Achr15

91486312

+SV2Bchr15

91809812

+
Frame-shiftENST00000394275ENST00000545111UNC45Achr15

91486312

+SV2Bchr15

91809812

+
Frame-shiftENST00000418476ENST00000394232UNC45Achr15

91486312

+SV2Bchr15

91809812

+
Frame-shiftENST00000418476ENST00000545111UNC45Achr15

91486312

+SV2Bchr15

91809812

+
In-frameENST00000553671ENST00000394232UNC45Achr15

91486312

+SV2Bchr15

91809812

+
In-frameENST00000553671ENST00000545111UNC45Achr15

91486312

+SV2Bchr15

91809812

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000553671UNC45Achr1591486312+ENST00000545111SV2Bchr1591809812+19838556961898400
ENST00000553671UNC45Achr1591486312+ENST00000394232SV2Bchr1591809812+106568556961898400

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000553671ENST00000545111UNC45Achr1591486312+SV2Bchr1591809812+0.005712230.9942878
ENST00000553671ENST00000394232UNC45Achr1591486312+SV2Bchr1591809812+0.001370950.9986291

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Fusion Genomic Features for UNC45A-SV2B


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
UNC45Achr1591486314+SV2Bchr1591809811+1.79E-081
UNC45Achr1591486314+SV2Bchr1591809811+1.79E-081

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for UNC45A-SV2B


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr15:91486312/chr15:91809812)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneUNC45Achr15:91486312chr15:91809812ENST00000394275+112321_54327930.0RepeatNote=TPR 1
HgeneUNC45Achr15:91486312chr15:91809812ENST00000394275+112358_91327930.0RepeatNote=TPR 2
HgeneUNC45Achr15:91486312chr15:91809812ENST00000394275+112392_125327930.0RepeatNote=TPR 3
HgeneUNC45Achr15:91486312chr15:91809812ENST00000418476+82021_54342945.0RepeatNote=TPR 1
HgeneUNC45Achr15:91486312chr15:91809812ENST00000418476+82058_91342945.0RepeatNote=TPR 2
HgeneUNC45Achr15:91486312chr15:91809812ENST00000418476+82092_125342945.0RepeatNote=TPR 3
TgeneSV2Bchr15:91486312chr15:91809812ENST00000330276412412_535336684.0Topological domainExtracellular
TgeneSV2Bchr15:91486312chr15:91809812ENST00000330276412557_565336684.0Topological domainCytoplasmic
TgeneSV2Bchr15:91486312chr15:91809812ENST00000330276412587_592336684.0Topological domainExtracellular
TgeneSV2Bchr15:91486312chr15:91809812ENST00000330276412614_626336684.0Topological domainCytoplasmic
TgeneSV2Bchr15:91486312chr15:91809812ENST00000330276412650_653336684.0Topological domainExtracellular
TgeneSV2Bchr15:91486312chr15:91809812ENST00000330276412673_683336684.0Topological domainCytoplasmic
TgeneSV2Bchr15:91486312chr15:91809812ENST00000394232513412_535336684.0Topological domainExtracellular
TgeneSV2Bchr15:91486312chr15:91809812ENST00000394232513557_565336684.0Topological domainCytoplasmic
TgeneSV2Bchr15:91486312chr15:91809812ENST00000394232513587_592336684.0Topological domainExtracellular
TgeneSV2Bchr15:91486312chr15:91809812ENST00000394232513614_626336684.0Topological domainCytoplasmic
TgeneSV2Bchr15:91486312chr15:91809812ENST00000394232513650_653336684.0Topological domainExtracellular
TgeneSV2Bchr15:91486312chr15:91809812ENST00000394232513673_683336684.0Topological domainCytoplasmic
TgeneSV2Bchr15:91486312chr15:91809812ENST00000545111412204_205185533.0Topological domainExtracellular
TgeneSV2Bchr15:91486312chr15:91809812ENST00000545111412227_237185533.0Topological domainCytoplasmic
TgeneSV2Bchr15:91486312chr15:91809812ENST00000545111412259_277185533.0Topological domainExtracellular
TgeneSV2Bchr15:91486312chr15:91809812ENST00000545111412299_390185533.0Topological domainCytoplasmic
TgeneSV2Bchr15:91486312chr15:91809812ENST00000545111412412_535185533.0Topological domainExtracellular
TgeneSV2Bchr15:91486312chr15:91809812ENST00000545111412557_565185533.0Topological domainCytoplasmic
TgeneSV2Bchr15:91486312chr15:91809812ENST00000545111412587_592185533.0Topological domainExtracellular
TgeneSV2Bchr15:91486312chr15:91809812ENST00000545111412614_626185533.0Topological domainCytoplasmic
TgeneSV2Bchr15:91486312chr15:91809812ENST00000545111412650_653185533.0Topological domainExtracellular
TgeneSV2Bchr15:91486312chr15:91809812ENST00000545111412673_683185533.0Topological domainCytoplasmic
TgeneSV2Bchr15:91486312chr15:91809812ENST00000330276412391_411336684.0TransmembraneHelical
TgeneSV2Bchr15:91486312chr15:91809812ENST00000330276412536_556336684.0TransmembraneHelical
TgeneSV2Bchr15:91486312chr15:91809812ENST00000330276412566_586336684.0TransmembraneHelical
TgeneSV2Bchr15:91486312chr15:91809812ENST00000330276412593_613336684.0TransmembraneHelical
TgeneSV2Bchr15:91486312chr15:91809812ENST00000330276412627_649336684.0TransmembraneHelical
TgeneSV2Bchr15:91486312chr15:91809812ENST00000330276412654_672336684.0TransmembraneHelical
TgeneSV2Bchr15:91486312chr15:91809812ENST00000394232513391_411336684.0TransmembraneHelical
TgeneSV2Bchr15:91486312chr15:91809812ENST00000394232513536_556336684.0TransmembraneHelical
TgeneSV2Bchr15:91486312chr15:91809812ENST00000394232513566_586336684.0TransmembraneHelical
TgeneSV2Bchr15:91486312chr15:91809812ENST00000394232513593_613336684.0TransmembraneHelical
TgeneSV2Bchr15:91486312chr15:91809812ENST00000394232513627_649336684.0TransmembraneHelical
TgeneSV2Bchr15:91486312chr15:91809812ENST00000394232513654_672336684.0TransmembraneHelical
TgeneSV2Bchr15:91486312chr15:91809812ENST00000545111412183_203185533.0TransmembraneHelical
TgeneSV2Bchr15:91486312chr15:91809812ENST00000545111412206_226185533.0TransmembraneHelical
TgeneSV2Bchr15:91486312chr15:91809812ENST00000545111412238_258185533.0TransmembraneHelical
TgeneSV2Bchr15:91486312chr15:91809812ENST00000545111412278_298185533.0TransmembraneHelical
TgeneSV2Bchr15:91486312chr15:91809812ENST00000545111412391_411185533.0TransmembraneHelical
TgeneSV2Bchr15:91486312chr15:91809812ENST00000545111412536_556185533.0TransmembraneHelical
TgeneSV2Bchr15:91486312chr15:91809812ENST00000545111412566_586185533.0TransmembraneHelical
TgeneSV2Bchr15:91486312chr15:91809812ENST00000545111412593_613185533.0TransmembraneHelical
TgeneSV2Bchr15:91486312chr15:91809812ENST00000545111412627_649185533.0TransmembraneHelical
TgeneSV2Bchr15:91486312chr15:91809812ENST00000545111412654_672185533.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneSV2Bchr15:91486312chr15:91809812ENST00000330276412130_148336684.0Topological domainExtracellular
TgeneSV2Bchr15:91486312chr15:91809812ENST00000330276412170_182336684.0Topological domainCytoplasmic
TgeneSV2Bchr15:91486312chr15:91809812ENST000003302764121_108336684.0Topological domainCytoplasmic
TgeneSV2Bchr15:91486312chr15:91809812ENST00000330276412204_205336684.0Topological domainExtracellular
TgeneSV2Bchr15:91486312chr15:91809812ENST00000330276412227_237336684.0Topological domainCytoplasmic
TgeneSV2Bchr15:91486312chr15:91809812ENST00000330276412259_277336684.0Topological domainExtracellular
TgeneSV2Bchr15:91486312chr15:91809812ENST00000330276412299_390336684.0Topological domainCytoplasmic
TgeneSV2Bchr15:91486312chr15:91809812ENST00000394232513130_148336684.0Topological domainExtracellular
TgeneSV2Bchr15:91486312chr15:91809812ENST00000394232513170_182336684.0Topological domainCytoplasmic
TgeneSV2Bchr15:91486312chr15:91809812ENST000003942325131_108336684.0Topological domainCytoplasmic
TgeneSV2Bchr15:91486312chr15:91809812ENST00000394232513204_205336684.0Topological domainExtracellular
TgeneSV2Bchr15:91486312chr15:91809812ENST00000394232513227_237336684.0Topological domainCytoplasmic
TgeneSV2Bchr15:91486312chr15:91809812ENST00000394232513259_277336684.0Topological domainExtracellular
TgeneSV2Bchr15:91486312chr15:91809812ENST00000394232513299_390336684.0Topological domainCytoplasmic
TgeneSV2Bchr15:91486312chr15:91809812ENST00000545111412130_148185533.0Topological domainExtracellular
TgeneSV2Bchr15:91486312chr15:91809812ENST00000545111412170_182185533.0Topological domainCytoplasmic
TgeneSV2Bchr15:91486312chr15:91809812ENST000005451114121_108185533.0Topological domainCytoplasmic
TgeneSV2Bchr15:91486312chr15:91809812ENST00000330276412109_129336684.0TransmembraneHelical
TgeneSV2Bchr15:91486312chr15:91809812ENST00000330276412149_169336684.0TransmembraneHelical
TgeneSV2Bchr15:91486312chr15:91809812ENST00000330276412183_203336684.0TransmembraneHelical
TgeneSV2Bchr15:91486312chr15:91809812ENST00000330276412206_226336684.0TransmembraneHelical
TgeneSV2Bchr15:91486312chr15:91809812ENST00000330276412238_258336684.0TransmembraneHelical
TgeneSV2Bchr15:91486312chr15:91809812ENST00000330276412278_298336684.0TransmembraneHelical
TgeneSV2Bchr15:91486312chr15:91809812ENST00000394232513109_129336684.0TransmembraneHelical
TgeneSV2Bchr15:91486312chr15:91809812ENST00000394232513149_169336684.0TransmembraneHelical
TgeneSV2Bchr15:91486312chr15:91809812ENST00000394232513183_203336684.0TransmembraneHelical
TgeneSV2Bchr15:91486312chr15:91809812ENST00000394232513206_226336684.0TransmembraneHelical
TgeneSV2Bchr15:91486312chr15:91809812ENST00000394232513238_258336684.0TransmembraneHelical
TgeneSV2Bchr15:91486312chr15:91809812ENST00000394232513278_298336684.0TransmembraneHelical
TgeneSV2Bchr15:91486312chr15:91809812ENST00000545111412109_129185533.0TransmembraneHelical
TgeneSV2Bchr15:91486312chr15:91809812ENST00000545111412149_169185533.0TransmembraneHelical


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Fusion Gene Sequence for UNC45A-SV2B


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>96829_96829_1_UNC45A-SV2B_UNC45A_chr15_91486312_ENST00000553671_SV2B_chr15_91809812_ENST00000394232_length(transcript)=10656nt_BP=855nt
AGAGACTGCGCCTGCGCGGGCACGAGACAACCTCTCCGCGATGACTGCCAGCTCAGTGGAGCAGCTGCGGAAGGAGGGCAATGAGCTGTT
CAAATGTGGAGACTACGGGGGCGCCCTGGCGGCCTACACTCAGGCCCTGGGTCTGGACGCGACGCCCCAGGACCAGGCCGTTCTGCACCG
GAACCGGGCCGCCTGCCACCTCAAGCTGGAAGATTACGACAAAGCAGAAACAGAGGCATCCAAAGCCATTGAAAAGGATGGTGGGGATGT
CAAAGCACTCTACCGGCGGAGCCAAGCCCTAGAGAAGCTGGGCCGCCTGGACCAGGCTGTCCTTGACCTGCAGAGATGTGTGAGCTTGGA
GCCCAAGAACAAAGTTTTCCAGGAGGCCTTGCGGAACATCGGGGGCCAGATTCAGGAGAAGGTGCGATACATGTCCTCGACGGATGCCAA
AGTGGAACAGATGTTTCAGATACTGTTGGACCCAGAAGAGAAGGGCACTGAGAAAAAGCAAAAGGCTTCTCAGAACCTGGTGGTGCTGGC
CAGGGAGGATGCTGGAGCGGAGAAGATCTTCCGGAGTAATGGGGTTCAGCTCTTGCAACGTTTACTGGACATGGGAGAGACTGACCTCAT
GCTGGCGGCTCTGCGTACGCTGGTTGGCATTTGCTCTGAGCATCAGTCACGGATCCTGCCCGGGAGCTGAAGGTCCTCATCAGTAACCTC
TTAGATCTGCTGACAGAGGTGGGGGTCTCTGGCCAAGGCCGAGACAATGCCCTGACCCTCCTGATTAAAGCGGTGCCCCGGAAGTCTCTC
AAGGACCCCAACAACAGCCTCACCCTCTGGGTCATCGACCAAGGTGTTTCCAACATCAAAACTCCCAAGCAAATGGATGAATTCATTGAG
ATCCAAAGTTCAACAGGAACCTGGTACCAGCGCTGGCTGGTCAGATTCAAGACCATTTTCAAGCAGGTCTGGGATAATGCCCTGTACTGT
GTGATGGGGCCCTACAGAATGAATACACTGATTCTGGCCGTGGTTTGGTTTGCCATGGCATTCAGTTACTATGGACTGACAGTTTGGTTT
CCTGATATGATCCGCTATTTTCAAGATGAAGAATACAAGTCTAAAATGAAGGTGTTTTTTGGTGAGCATGTGTACGGCGCCACAATCAAC
TTCACGATGGAAAATCAGATCCACCAACATGGGAAACTTGTGAATGATAAGTTCACAAGAATGTACTTTAAACATGTACTCTTTGAGGAC
ACATTCTTTGACGAGTGCTATTTTGAAGACGTAACATCAACAGATACCTACTTCAAAAATTGTACCATTGAATCAACCATCTTTTACAAC
ACAGACCTCTACGAGCACAAGTTCATCAACTGTCGGTTTATCAACTCCACCTTCCTGGAGCAGAAGGAGGGCTGCCACATGGACTTGGAG
CAAGATAATGACTTCCTGATTTACCTCGTCAGCTTCCTGGGCAGCCTGTCTGTCTTACCCGGGAACATCATTTCTGCCCTGCTCATGGAT
AGAATTGGAAGGCTCAAGATGATTGGTGGCTCCATGCTAATCTCTGCAGTCTGCTGCTTCTTCCTGTTTTTTGGCAACAGTGAGTCTGCA
ATGATCGGCTGGCAGTGCCTGTTCTGTGGGACAAGCATTGCAGCCTGGAATGCTCTGGATGTGATCACAGTGGAGCTGTATCCCACCAAC
CAGAGAGCAACAGCCTTCGGCATTCTCAATGGATTATGCAAATTTGGCGCCATCCTGGGAAACACCATCTTTGCTTCTTTTGTTGGGATA
ACCAAAGTGGTCCCCATCCTTCTGGCTGCTGCTTCTCTGGTTGGGGGTGGCCTGATTGCCCTTCGACTGCCAGAGACTCGAGAACAGGTC
CTGATGTGAACAACCTATGGGAAAAGGAAAGGTCGAGAGAATCTTGTCCAGGACACTGAAATGCATCCACACTTCCTGCCTATCACGGTC
CGGAGGACACCTTGGATAGCACGGGAGGAGAAGTTGACTTTGTGACCCCTAGTTTAGGACCCACTTCAGCTGTCAATATGTTTGTAACTC
AGGTGACTGATTTGGGGGTGCCCTGAGCCACCCTTAGAATCACAGAGCTGCGTGTTTAACTTCAAGTCTTCCCAGTCCAAGGCAGGGAGA
GGATTCTCCAGTGAGTGCACACACTATGCGAGGAGCAAGCATTTCTCTAAGTCAAGTGCAAGGACTTAACTTGCGTTTGAAAAGGAATTA
GAGGGTCAGAAACACCCAGGTTCCTCCAGAAAGCTCCTTGGAGCCCAACAACTTAACAAATCAACTTGGCTGGAAGTTAGAGTCATTATA
TGAAGATTGGGCTTGAAGTATATATTTTTGCATTTAAAAGTATCACCTATCATATTTTCCACTCGAAAATTGACATAGTAGCATTGAGGA
TACTCTGATCTAGAAAGCCAAGTATTTGAGCAACATCTATAGAGATCTACTTTTCTCCTATGTCTCCTAGGCTTTCCATGATAATTAGGT
AATACATTTAAGAAGGATATTTATTTCTGTTTTGCTCTATTCAAAGAAACGGAATGGGATAGTTATTCTGTAAACTAAGTTTGTATATAA
CTTTATTTGGGTTTAATTTCCACAACTGGTATCTGCAAATATTGCCAGCATTTTAGCCATATTTTGGGAGAACTTGGTGTTTGAGGTCCC
AGGAAATGAGGTCTGATCAAATGAAATGCAAGCACAATTTCTTACAGCCATTTAACTTTCTGTTGGGAGGATGAATTAACAAACTCACAT
TGTGCAGTCTGCTTAATCCAGGCACTTTTCTTTGTGCAGGTGTAGTGAGTAGTTACTTCTCTCCCTTACACAGATGACTTGTGAAACTCA
AGCTCACCATCTTCAGTGCTGGCATTTTACTTTGCCACTACCCAAAAACAATGTGAGATGTGTTCAGTGGCCTCTGGTACTCTTTGCAGG
CAAGAATCAAACAACATGGGGACTGAGGGAAGGATGGGGAAGTGTAGCCACAGTTCTTCCAAATGTAAATACTTTTTGTTTGTTCTAGTG
GTAAAATGCAAATGCAATCCATATTTGTTAGGATGGTCAGGTCTCATGAGAAATCTATGCTATGTGTCCAGAGCTTTTGAAACAGAGTCC
ATTGGAGTGGGAGTTAGGGAGTGTAGTGGATGCCAAATATGTTTTTCTTCAGTGCTTAAGAGAACTGTTTCCTGAAGTCCAGCTTTGAAC
ATAAACAGGGGTGTGGGTTGGGGGAGGAGCTTAGGACAAACCTCTCTGATGAAGGTCAGCAATAGACTGAAGTCTTGACTGCATGGAAGA
GGAAAAACATCAGAACTGTCTGACAATGGAGGGGACAGTGAGCTACGCACAACTGCCAGCGGAGGTGAACTTGCACCTGCCCAGGCCGGA
TGAACATCAGCCTGCAAGAACTAGTTGTTTGAGTTGATTTGCAGTGCTCTCAATGGGCAAGTGCCACATTTTCCCTGGCAGAGATCTCCA
AAAATTTAAAACAGAATAATAATGGCTATATCGAGTGTTTTCTCAGTATTGGAGAAATGCTTAGGTCCTATGATAGCTTCGGGACATCTT
TCTGTAATTTTCCTCAATTAACGGGTTGGTAGGGGTAAATCTTATGACACCTTTCCACCGTCGATTTGAGATCAGTTTTAATGGTTAAAA
TGTTTACTCTCCTTCTGTCAACCCTCACCTTTTTATTTACACCCCTCCCTTTTTTTCTGTACAGGGAGAGAAGACATATTGACTCTGACT
GGACACCCTGATTCCTCCAAATATATATACCACTGTGTATTAATCTTTCTCTCAGTGTTTTATAGGAGTACTAACATTTATTGCTCTGTC
AATAATGAAAGGCTCGATGTAATATAGCTGTAATTTACTTTCCATATGAATACAGTGGCTAGGTTCATAAAAGAGAATTGTGTGAGTCTG
GGATTACCACATCTAAAACATTATTCTTTAATGGGATAATACAATTCATTGAGCAGCTACCACTTAAAAAACTTGCAGGACAGTTAGAGC
CTGCATTTCTAGTTAAGATGGATCTTGTAAATTTAAAATTGGATTAACATTGGAGTGCTGGGGTGGCTGCAATAATTTGGGGGCTAACTC
CATTTGGTTTCCAAGATCTCACTTCTGCATTATCTTTATGGCTCTTTAAACCAGCCACCTAGCCAATCAAGGGCAATTCCCATCTCATCC
ATCACTCAGGTCTTTGTAAAGGGTGCAGCCAAGCTCTGCAGACTTTTGCAGGATTGTCTAGCCTGAGTACCGGGCTACTTCTTAAATGCC
GTCACTCCTGCTGAGATAAATGCGTCTTTAAAAATAGTCTCTGTGGCAGGTCACTGGGGGACAATGTACAGCATTCTGGCCATCCACTTC
TTTTTCACTTCATGTTCTACCCCAAGAGACTCCCGATGTCGGCTGTGGAGGGTTAAAGGGATGAGGCTTTCCTTTGTTTAGCAAATCTGT
TCACAGTTCTTGATGATGTATTTTATGATGCCCAGCTTGGAAATAGTTGCTTTCCATAGTCTCAACTGTATTGTGTCATCTCCTGATGCT
GATTTTTGATCTTTTGTTTTATTAAAAATAATTAGTGAAAGAGGTGTGCCTATCTGTGAAGTTTGTAGTACATCATCCTGAGGTCATGTA
ACAAGTAAACCCCAACCCAGCGTTCCCTCCTACGTTGTGTTAGTTCATTAAAACTAAATAATAAAAATAACTGTAAGAAAACCTTAAGGA
CTGGGGTTAGAGATTATTTTCAGGCACTAAGGTCTCTTCTGTATTCCAAAATTGATTGAATCAGCTGGGAGAAACATTGAGAATCGCTTC
CTTCAACTTTTATTTTGCAACATGGGGACCTTGAGAGGTTAAACGATGTGGCCCAGATTACATGTAATGTGAGGAGTGGGCGAGAAGGCC
TAAGGTGATGCTCTCATGACAGTTCTGGGGAAGCCTGCAGTTTGGGGAATGGGACAATGTGACAAATACTCGCCATTCCCTGAGACCATT
CATTGACTATTCCCTTGATGGCTTTACTATAATGAGAGGAAGCATCAGTTTAAACATAAAAAGATTAGTATTTATCCATCCATTTATTCA
TTCAGCAAATCCTTATTGAGCCCTGACCATGGGCCAGTCTCTCTGCCAAGCCCTGGGGACACAGTGATGAAAAAACTGGCCACAGTTTCT
GCTTCCTGCCTCATTCCACTTGCAGTGAGCGGATATTAAATTGGCCATAAACACCGAGTACGATGACCTTACAATCCGCAAACTGCACCT
TTCATGTGTAAAAGGATTGCTACTACTTTACTTGTCAGCTGTGGATTTCCAAATGTGGTGGCTCCCTCTTATTTTTTTTTCTTTGAGGAG
TGTACCAATTTTTTATCTTTATAAACCAGGTAAGGGAAATGATGCCCTTGCCCATTTTCTACAGACCTAATCGATTTTTACCTAATCAGT
TTTACAGAAAGGGTTACATGGAAGAAGAGATAGGGGCCAGGAATGCAAGAGGGACATTGGTGAGTGGGGTAAGAATCCCCGTAGCCCTGG
GAAAGGTGTCTCCACTTCCACATCTGGCTTTTCTAGGGGGCATCTGTGCTAACTGACCTGGGATTATGTTGGATGGCATATGACTGCAAA
TTCAAAGAAACCAATTTATAATAAGTTTATAGTAAGTTAAAGGTTTGTTTTACTCTCATGTGAAGGGAATCTGGAGGAAGGAAAGCCAGG
GCTGGAGTGGCTGCCTTTGATCATGGGAGCACACTCCTTCTGCCCGATCATTGGGAGCACACTCCTTCTGCCTGATCGTTGGGAGCACAC
TCCTGCCTGATCATGGGCGCACGTTCCTTCTGCCTGATCGTTGGGAGCACACTCCTTCTGCCTGATCATGGGAGCACACTCCTTCTGCCT
GATCATTGGGAGCACGCTCCTTCTGCCTGATCGTTGGGAGCACACTCTTTCTGCCTGATCGTTGGGAGCACACCCCTTCTGCCTGATCAT
TGGGAGCACACTCCTTCTGCCTGATCATGGGCACACGCTCCTTCTGCCCGATCATGGGCACACGCTCCTTCTGCCCGATCGTTGGGAGCA
CACTCCTTCTGCCCAATCATTGGGCTCACGCTCCTTCTGCCCGATCGCTGGGCTCACGCTCCTTCTGCCCGATCTTGGGCGCACGCTCCT
TCTGCCCGATCGTTGGGCGCACGCTCCTTCTGCCCGATCGTTGGGCGCATGCTCCTTCTGCCCGATCGTTGGGAGCACGCTCATTCTGCC
CGATTGTTGGGAGCACGCTCCTTCTGCCCGATCGTTGGGCGCACGCTCCTTCTGCCCGATCGTTGGGCGCACGCTTCTTCTGCCTGATCG
TTGGGCGCACGCTCCTTCTGCCTGATCGTTGGGCGCACGCTCCTTCTGCCTGATCGTTGGGAGCACGCTCCTTCTGCCTGATTGTTGGAA
GCACGCTCCTTCTGCCTTCAGACTCCTTGATTTTTAGTGCAGTTTCCATCACTGAGGCTGCCTCATGGGCTGAGATGGCTGTTGAAGCAC
TGAACCTCACATCCACAATTCAGGCAGGAAGCAGAAGGAAGGGCAATGGGCAAAGGGGCTGTGCCTTGCAGCCGATCCAGCCTCCCTTTG
CTGCAGAGGAGGCAGGGAAATGCGGTATTTACTGGGAACATTGCTGCCCCTCCTCCAAATTGAGGGTCTTGGCTCGAAGGACAAAAGCCA
GAAAGGATAGGTGGATTAGTGCTTCTTAAACTTTTGCGTGCATCAGAATCACCCAGAAAGATGTTAAAACTCACTCTTCAAGGCCCCATC
CCCAGAGATTCGGATTCTGGGGATTTGGAATCTGGGGTGGGGTCTGAAGAATCTGCATTTTTTAACAAACTCCCAGGTGACATAGATGGC
ATCAATTCTCAAGCCATATTTTGAGTAGCACTGACACTCTTCCAATAGGTGGTACTTTGACTTGTCAGGGAAGTTCTATTGCTCTGATAA
CTTAAAACCAACCCAACCAGAAGCTCACAAAAACTAGCAGCCTGTGAAAAATGATCACCATTTTCCTAGAGCTCCGAGACAACTAGTGGT
AGTGCAACAGTAACCCAAAAATGTCAATGAAAATATTTCCTTCCCCAGAAACTGCTTGGTTTCACTCAGGTCCTGTCCTTATGGGCCTGT
GTCTGGTTGCAGGGCTTGAAGTATTTCGGAAGCTCAGCAGAGGTTGAACCCTTTCCCCTGGGGGTTGGTGATCTTTGTTTTGGCCATTTC
CACCTGGTGAAGATTTTCATAGACAAATATGCTTGTGGCATCCTGTAATTCATTGTGCCTTATGATGGACCTCTGATTCTATAAGCTTCC
CCCTAGCTAGGGATGCACGGGGGTGATCAAGACATGACTAGATGTGAACCTGACCTGCAGACAGTCCACCTGAACGTGCCTGGAAATGTC
TCCCGAAAAGGATGAAAAGCCTCCTCCTTTAGACAAGGAAGACAGAGTGGAGCAAATTTCTCTACATAGATCTCATTCGAAAACAAATTT
ACAGAATGCAGAATGGCTACTGTGTGTCTTGTGCTATGCTAGGTCTCTCTCTCTCTAAGTGGACTCTGACCCTGTCCAAAACATTGTGCT
TTTGCATGTAGCTGTGTCGCATTTAGGCCCAGCTCTAAGAACCGTTTGGAAATAAATCACATAGAGCCTTTGATTGTGAGGCAGGCTTAA
AGTACATTTTGTTTGATTTGCAGAGGCATGGTGAGGAATTTATATGCATGGCTGTTGTGGCAGCAGCGAGATTTCCAAAAAGATGAATGA
TGAAATGAAACAGACTGAAGCTATCTCACAAATGTTAAATGGAGAAATAAAAGTTGTTATAGTCATTGCTAATTACAGAATGAGCAAGAG
ATTTATTTAGCAGGACCATACTATGCCCCCTGGAAGGTTCAGTTTATGAGCTGGAGCACAAGGATTTACTGTCATTTCACCTGAAAACAC
ACATTTAGCTGTCCATTTACCTTTAATCCTACAGGCTTAAAATACTTTAAAATTTCAGAGACCATTAATATGTATTCCTTTAGAAAGCAA
AGGTCTTTCAGAAGCTGTCCTCTACCAAAGTTAATGTGGTCACCACATTTGATGATTTTGCTAGGTAGGGAGGTTTATTTAATCACAGCT
ACTGTCACTCAGGAGGATGAGCCATTTAAAAATGGTGGCCCTGTCCTCCACTTCTTACCTACCATATATAATCTCAGTAATTCAGATTTC
TCTAAATCAGCATTAGTGATCATTTCAATAGGGTATGAACAAAAGGCCTATAAAAATAGCTTTCCAATTCGCCACCAAAAATGCAAAAAT
GACAAGTAAGTGAGGTAACGCATGAGCTAAATAGCTTGATTTAGTCACTCTAAAATGTGGGTGTGTATATATACATACATATATATACAC
ACACACATTATGTTATACACCATAAATATATAGAAGTTTTACTTGTCAATTAAAACTATAAATAAAGTGGCTTTCCAGAAAAATTAGATA
TTGGACTCTATCACAAAGGAATTGCATAAAAATACTTACAAACATAACTATAAGCAATTGATGAGCAAATTACAAATGACTGTTTTTTAT
TAAAACATTCCTCCAAAAGAACGGCAAAGCAAATCCCATAGACACCCAAAATACTAAAAGTGACAAAACAATACTTCTTTAAAAATGTAT
TTTATGATCTATTTATTGATATTCTAATGGTTTTAAGAAGGATAATTTTCCAAAACCTAAATGCTACACATTTTACAGTGGCAATATCAA
CCTTATCATGAGCTAAAGATTTGCAATCAGAACATTGGTAGAGTGCATTGCTGAGTTATAACAAGTGTCTCAGGACGAGGATATTTGGTA
GGTATCCTTAAATATATAGATGCTTACCAGTAGGTTTAATAGAAGATTTCTGAAAGGTAGCGCAAGTTTTTATTTCATTATTTTTATTTT
TATTTTTTTGAGACAGAGTCTCACTCTGTCATCTAGGCTGGAGTGCAGTGGTGCAATCTTGGCTTGCTGCAATCTCCACCTCCCAGGTTC
AAGCGATTCTCCCACCTCAGCCTCCCGAGTAGCTGGGATTACAGGCATGCGCCACCATGCCTGGCTAATTTTTGTATTTTTAGTAGAGAC
GGGGTTTCGCCATGTTGGCCAGGCTCGTCTCGAACTCCTGGCCTCAAGTGATCTGCCCGCCTCAGCCTCCCAAAGTGCTGGGATTACAAA
TGTGAGCTACTATGCCTGGTCCCAACTTCTTAAAATTAAATTTTGGGGAAGTTCATGGAGATATTTTTGACATGTAAAAGTAGAAAACAA
ACCATCCATAGTGTGTGCATATATACACACAAGGTTTGGTTTAATATACTTGCTGTGCACTAGTCAGTTTTGATTCAGGTTACATAAGGG
ATAAAATATAGAAAGACATTTTAAAGTTTGAAATATGTGCTAAGTAGTTAGAGATTTGGCAGTTTTGCCACATTTCAAATGGGCCAAACA
TTAAAATAACTTATCCATGAATTTCAGGTTTCAAGGAAGGAGGAATATCTGACTATTTTTTTTTGTGTGTGAGATTTGGTCTCAGCTTTT
TGGTCCATCTGAATCCTGGAAGTCCCCAACTCTACCAGACCAAAAGGGTGTCTCTATTTTTTGTTGTTACTTCTCTGTTCTTGATGTAAT
GAGTTAAGTAGATGAAAGAGATTAAGGTGCAGGGAAGGGCTCTTAAAAGTTTAATGTTTCAGCTTTCCATAGTCATTCATACTTGTGAAT
CTTCTTCCTCTTCTACTTCAAAGTAGCCAAAACTTGGAAAGTTCAAATTAATCTTTGGGCTCCAAAGAGCAATTCTGAAGGATTAACAGG
TTTCATTCTCTCCAGTGGGAGGTGGCCTAGACAGGTGCCGGTTTTGGGGAGAGGTGAGAGTACCCAGATGTGGGTGACTATTTCCTGTTC
TTCCCTGAAAGTCAGGCCAGTGGTCTCGAATCATTCCCACAGCAACTGCTACAAAAGTGACTATCTTAATCCTTTGGCTAGATGGGATAC
CTCTTCTACCTTTTCAGAGGTGAGCTGTTGAGTAGTAATGTCCGCTACAACACCACGCTCCCGGAATGGTGGTTCCTAAGAGCAAAGTCA
GTTAATACAATTTCTCCAGGTATCCAGCTATCTCCAGGTGTGCGGTCCTGTGAAGCACTCTAAGAACTGTAAAAAATATTTCATAGGTAT
AGAAGGCATTTGTAATACTGTTGGTTCAAATGTGCTGACATGTAGCCAGTGGAGGAAGATGTTTCTTTGGAAGCCTGCCATCTTTCTGTA
ACGCACCTTCAACCTGAGATAATTAAGAGTCATTACGTTTCCCAGTCCCATGTCACATTGACCAGTCCTGTGGTCCTATGGCTAAGCGGA
GGACACGGCCACAAGCTGTGAGTCATGAAAAGGAGGGTGCAGGTGATAGGCAAAGGGACCCATTAGCCAGTTTACAATGACTGGCAACTG
ACCAGATAGAGCTTACCGTATGTCCATGTAGAGTTGCTCATATTAGTCTGTAAATAATTCTATGCATAGTGAATGCAGCTTCTGAATTAT

>96829_96829_1_UNC45A-SV2B_UNC45A_chr15_91486312_ENST00000553671_SV2B_chr15_91809812_ENST00000394232_length(amino acids)=400AA_BP=1
MKVLISNLLDLLTEVGVSGQGRDNALTLLIKAVPRKSLKDPNNSLTLWVIDQGVSNIKTPKQMDEFIEIQSSTGTWYQRWLVRFKTIFKQ
VWDNALYCVMGPYRMNTLILAVVWFAMAFSYYGLTVWFPDMIRYFQDEEYKSKMKVFFGEHVYGATINFTMENQIHQHGKLVNDKFTRMY
FKHVLFEDTFFDECYFEDVTSTDTYFKNCTIESTIFYNTDLYEHKFINCRFINSTFLEQKEGCHMDLEQDNDFLIYLVSFLGSLSVLPGN
IISALLMDRIGRLKMIGGSMLISAVCCFFLFFGNSESAMIGWQCLFCGTSIAAWNALDVITVELYPTNQRATAFGILNGLCKFGAILGNT

--------------------------------------------------------------
>96829_96829_2_UNC45A-SV2B_UNC45A_chr15_91486312_ENST00000553671_SV2B_chr15_91809812_ENST00000545111_length(transcript)=1983nt_BP=855nt
AGAGACTGCGCCTGCGCGGGCACGAGACAACCTCTCCGCGATGACTGCCAGCTCAGTGGAGCAGCTGCGGAAGGAGGGCAATGAGCTGTT
CAAATGTGGAGACTACGGGGGCGCCCTGGCGGCCTACACTCAGGCCCTGGGTCTGGACGCGACGCCCCAGGACCAGGCCGTTCTGCACCG
GAACCGGGCCGCCTGCCACCTCAAGCTGGAAGATTACGACAAAGCAGAAACAGAGGCATCCAAAGCCATTGAAAAGGATGGTGGGGATGT
CAAAGCACTCTACCGGCGGAGCCAAGCCCTAGAGAAGCTGGGCCGCCTGGACCAGGCTGTCCTTGACCTGCAGAGATGTGTGAGCTTGGA
GCCCAAGAACAAAGTTTTCCAGGAGGCCTTGCGGAACATCGGGGGCCAGATTCAGGAGAAGGTGCGATACATGTCCTCGACGGATGCCAA
AGTGGAACAGATGTTTCAGATACTGTTGGACCCAGAAGAGAAGGGCACTGAGAAAAAGCAAAAGGCTTCTCAGAACCTGGTGGTGCTGGC
CAGGGAGGATGCTGGAGCGGAGAAGATCTTCCGGAGTAATGGGGTTCAGCTCTTGCAACGTTTACTGGACATGGGAGAGACTGACCTCAT
GCTGGCGGCTCTGCGTACGCTGGTTGGCATTTGCTCTGAGCATCAGTCACGGATCCTGCCCGGGAGCTGAAGGTCCTCATCAGTAACCTC
TTAGATCTGCTGACAGAGGTGGGGGTCTCTGGCCAAGGCCGAGACAATGCCCTGACCCTCCTGATTAAAGCGGTGCCCCGGAAGTCTCTC
AAGGACCCCAACAACAGCCTCACCCTCTGGGTCATCGACCAAGGTGTTTCCAACATCAAAACTCCCAAGCAAATGGATGAATTCATTGAG
ATCCAAAGTTCAACAGGAACCTGGTACCAGCGCTGGCTGGTCAGATTCAAGACCATTTTCAAGCAGGTCTGGGATAATGCCCTGTACTGT
GTGATGGGGCCCTACAGAATGAATACACTGATTCTGGCCGTGGTTTGGTTTGCCATGGCATTCAGTTACTATGGACTGACAGTTTGGTTT
CCTGATATGATCCGCTATTTTCAAGATGAAGAATACAAGTCTAAAATGAAGGTGTTTTTTGGTGAGCATGTGTACGGCGCCACAATCAAC
TTCACGATGGAAAATCAGATCCACCAACATGGGAAACTTGTGAATGATAAGTTCACAAGAATGTACTTTAAACATGTACTCTTTGAGGAC
ACATTCTTTGACGAGTGCTATTTTGAAGACGTAACATCAACAGATACCTACTTCAAAAATTGTACCATTGAATCAACCATCTTTTACAAC
ACAGACCTCTACGAGCACAAGTTCATCAACTGTCGGTTTATCAACTCCACCTTCCTGGAGCAGAAGGAGGGCTGCCACATGGACTTGGAG
CAAGATAATGACTTCCTGATTTACCTCGTCAGCTTCCTGGGCAGCCTGTCTGTCTTACCCGGGAACATCATTTCTGCCCTGCTCATGGAT
AGAATTGGAAGGCTCAAGATGATTGGTGGCTCCATGCTAATCTCTGCAGTCTGCTGCTTCTTCCTGTTTTTTGGCAACAGTGAGTCTGCA
ATGATCGGCTGGCAGTGCCTGTTCTGTGGGACAAGCATTGCAGCCTGGAATGCTCTGGATGTGATCACAGTGGAGCTGTATCCCACCAAC
CAGAGAGCAACAGCCTTCGGCATTCTCAATGGATTATGCAAATTTGGCGCCATCCTGGGAAACACCATCTTTGCTTCTTTTGTTGGGATA
ACCAAAGTGGTCCCCATCCTTCTGGCTGCTGCTTCTCTGGTTGGGGGTGGCCTGATTGCCCTTCGACTGCCAGAGACTCGAGAACAGGTC
CTGATGTGAACAACCTATGGGAAAAGGAAAGGTCGAGAGAATCTTGTCCAGGACACTGAAATGCATCCACACTTCCTGCCTATCACGGTC

>96829_96829_2_UNC45A-SV2B_UNC45A_chr15_91486312_ENST00000553671_SV2B_chr15_91809812_ENST00000545111_length(amino acids)=400AA_BP=1
MKVLISNLLDLLTEVGVSGQGRDNALTLLIKAVPRKSLKDPNNSLTLWVIDQGVSNIKTPKQMDEFIEIQSSTGTWYQRWLVRFKTIFKQ
VWDNALYCVMGPYRMNTLILAVVWFAMAFSYYGLTVWFPDMIRYFQDEEYKSKMKVFFGEHVYGATINFTMENQIHQHGKLVNDKFTRMY
FKHVLFEDTFFDECYFEDVTSTDTYFKNCTIESTIFYNTDLYEHKFINCRFINSTFLEQKEGCHMDLEQDNDFLIYLVSFLGSLSVLPGN
IISALLMDRIGRLKMIGGSMLISAVCCFFLFFGNSESAMIGWQCLFCGTSIAAWNALDVITVELYPTNQRATAFGILNGLCKFGAILGNT

--------------------------------------------------------------

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Fusion Gene PPI Analysis for UNC45A-SV2B


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for UNC45A-SV2B


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for UNC45A-SV2B


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource