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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:UQCRC2-BAZ1B (FusionGDB2 ID:97007) |
Fusion Gene Summary for UQCRC2-BAZ1B |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: UQCRC2-BAZ1B | Fusion gene ID: 97007 | Hgene | Tgene | Gene symbol | UQCRC2 | BAZ1B | Gene ID | 7385 | 9031 |
| Gene name | ubiquinol-cytochrome c reductase core protein 2 | bromodomain adjacent to zinc finger domain 1B | |
| Synonyms | MC3DN5|QCR2|UQCR2 | WBSCR10|WBSCR9|WSTF | |
| Cytomap | 16p12.2 | 7q11.23 | |
| Type of gene | protein-coding | protein-coding | |
| Description | cytochrome b-c1 complex subunit 2, mitochondrialcomplex III subunit 2cytochrome bc-1 complex core protein IIubiquinol-cytochrome c reductase core protein IIubiquinol-cytochrome-c reductase complex core protein 2 | tyrosine-protein kinase BAZ1BhWALp2transcription factor WSTFwilliams syndrome transcription factorwilliams-Beuren syndrome chromosomal region 10 proteinwilliams-Beuren syndrome chromosomal region 9 protein | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | . | Q9UIG0 | |
| Ensembl transtripts involved in fusion gene | ENST00000268379, ENST00000561553, | ENST00000339594, ENST00000404251, | |
| Fusion gene scores | * DoF score | 12 X 8 X 6=576 | 10 X 11 X 5=550 |
| # samples | 13 | 13 | |
| ** MAII score | log2(13/576*10)=-2.14755718841386 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(13/550*10)=-2.08091999538357 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: UQCRC2 [Title/Abstract] AND BAZ1B [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | UQCRC2(21964777)-BAZ1B(72892899), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | BAZ1B | GO:0006974 | cellular response to DNA damage stimulus | 19092802 |
| Tgene | BAZ1B | GO:0016572 | histone phosphorylation | 19092802 |
| Fusion gene breakpoints across UQCRC2 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across BAZ1B (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | Non-Cancer | TCGA-CG-5720-11A | UQCRC2 | chr16 | 21964777 | + | BAZ1B | chr7 | 72892899 | - |
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Fusion Gene ORF analysis for UQCRC2-BAZ1B |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000268379 | ENST00000339594 | UQCRC2 | chr16 | 21964777 | + | BAZ1B | chr7 | 72892899 | - |
| In-frame | ENST00000268379 | ENST00000404251 | UQCRC2 | chr16 | 21964777 | + | BAZ1B | chr7 | 72892899 | - |
| In-frame | ENST00000561553 | ENST00000339594 | UQCRC2 | chr16 | 21964777 | + | BAZ1B | chr7 | 72892899 | - |
| In-frame | ENST00000561553 | ENST00000404251 | UQCRC2 | chr16 | 21964777 | + | BAZ1B | chr7 | 72892899 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000268379 | UQCRC2 | chr16 | 21964777 | + | ENST00000339594 | BAZ1B | chr7 | 72892899 | - | 5669 | 797 | 764 | 4357 | 1197 |
| ENST00000268379 | UQCRC2 | chr16 | 21964777 | + | ENST00000404251 | BAZ1B | chr7 | 72892899 | - | 4989 | 797 | 764 | 4357 | 1197 |
| ENST00000561553 | UQCRC2 | chr16 | 21964777 | + | ENST00000339594 | BAZ1B | chr7 | 72892899 | - | 4958 | 86 | 53 | 3646 | 1197 |
| ENST00000561553 | UQCRC2 | chr16 | 21964777 | + | ENST00000404251 | BAZ1B | chr7 | 72892899 | - | 4278 | 86 | 53 | 3646 | 1197 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000268379 | ENST00000339594 | UQCRC2 | chr16 | 21964777 | + | BAZ1B | chr7 | 72892899 | - | 0.001178051 | 0.9988219 |
| ENST00000268379 | ENST00000404251 | UQCRC2 | chr16 | 21964777 | + | BAZ1B | chr7 | 72892899 | - | 0.001387905 | 0.99861205 |
| ENST00000561553 | ENST00000339594 | UQCRC2 | chr16 | 21964777 | + | BAZ1B | chr7 | 72892899 | - | 0.000676393 | 0.9993236 |
| ENST00000561553 | ENST00000404251 | UQCRC2 | chr16 | 21964777 | + | BAZ1B | chr7 | 72892899 | - | 0.000854701 | 0.99914527 |
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Fusion Genomic Features for UQCRC2-BAZ1B |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for UQCRC2-BAZ1B |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr16:21964777/chr7:72892899) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | BAZ1B |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: Atypical tyrosine-protein kinase that plays a central role in chromatin remodeling and acts as a transcription regulator. Involved in DNA damage response by phosphorylating 'Tyr-142' of histone H2AX (H2AXY142ph). H2AXY142ph plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Essential component of the WICH complex, a chromatin remodeling complex that mobilizes nucleosomes and reconfigures irregular chromatin to a regular nucleosomal array structure. The WICH complex regulates the transcription of various genes, has a role in RNA polymerase I and RNA polymerase III transcription, mediates the histone H2AX phosphorylation at 'Tyr-142', and is involved in the maintenance of chromatin structures during DNA replication processes. In the complex, it mediates the recruitment of the WICH complex to replication foci during DNA replication. {ECO:0000269|PubMed:11980720, ECO:0000269|PubMed:15543136, ECO:0000269|PubMed:16603771, ECO:0000269|PubMed:19092802, ECO:0000269|PubMed:19234442}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | BAZ1B | chr16:21964777 | chr7:72892899 | ENST00000339594 | 5 | 20 | 1245_1283 | 297 | 1852.6666666666667 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | BAZ1B | chr16:21964777 | chr7:72892899 | ENST00000339594 | 5 | 20 | 533_586 | 297 | 1852.6666666666667 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | BAZ1B | chr16:21964777 | chr7:72892899 | ENST00000339594 | 5 | 20 | 768_814 | 297 | 1852.6666666666667 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | BAZ1B | chr16:21964777 | chr7:72892899 | ENST00000339594 | 5 | 20 | 850_893 | 297 | 1852.6666666666667 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | BAZ1B | chr16:21964777 | chr7:72892899 | ENST00000404251 | 5 | 19 | 1245_1283 | 297 | 1484.0 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | BAZ1B | chr16:21964777 | chr7:72892899 | ENST00000404251 | 5 | 19 | 533_586 | 297 | 1484.0 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | BAZ1B | chr16:21964777 | chr7:72892899 | ENST00000404251 | 5 | 19 | 768_814 | 297 | 1484.0 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | BAZ1B | chr16:21964777 | chr7:72892899 | ENST00000404251 | 5 | 19 | 850_893 | 297 | 1484.0 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | BAZ1B | chr16:21964777 | chr7:72892899 | ENST00000339594 | 5 | 20 | 1261_1273 | 297 | 1852.6666666666667 | Compositional bias | Note=Poly-Glu | |
| Tgene | BAZ1B | chr16:21964777 | chr7:72892899 | ENST00000339594 | 5 | 20 | 306_578 | 297 | 1852.6666666666667 | Compositional bias | Note=Lys-rich | |
| Tgene | BAZ1B | chr16:21964777 | chr7:72892899 | ENST00000404251 | 5 | 19 | 1261_1273 | 297 | 1484.0 | Compositional bias | Note=Poly-Glu | |
| Tgene | BAZ1B | chr16:21964777 | chr7:72892899 | ENST00000404251 | 5 | 19 | 306_578 | 297 | 1484.0 | Compositional bias | Note=Lys-rich | |
| Tgene | BAZ1B | chr16:21964777 | chr7:72892899 | ENST00000339594 | 5 | 20 | 1356_1426 | 297 | 1852.6666666666667 | Domain | Bromo | |
| Tgene | BAZ1B | chr16:21964777 | chr7:72892899 | ENST00000339594 | 5 | 20 | 604_668 | 297 | 1852.6666666666667 | Domain | DDT | |
| Tgene | BAZ1B | chr16:21964777 | chr7:72892899 | ENST00000404251 | 5 | 19 | 1356_1426 | 297 | 1484.0 | Domain | Bromo | |
| Tgene | BAZ1B | chr16:21964777 | chr7:72892899 | ENST00000404251 | 5 | 19 | 604_668 | 297 | 1484.0 | Domain | DDT | |
| Tgene | BAZ1B | chr16:21964777 | chr7:72892899 | ENST00000339594 | 5 | 20 | 1184_1234 | 297 | 1852.6666666666667 | Zinc finger | PHD-type | |
| Tgene | BAZ1B | chr16:21964777 | chr7:72892899 | ENST00000404251 | 5 | 19 | 1184_1234 | 297 | 1484.0 | Zinc finger | PHD-type |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | BAZ1B | chr16:21964777 | chr7:72892899 | ENST00000339594 | 5 | 20 | 20_126 | 297 | 1852.6666666666667 | Domain | WAC | |
| Tgene | BAZ1B | chr16:21964777 | chr7:72892899 | ENST00000404251 | 5 | 19 | 20_126 | 297 | 1484.0 | Domain | WAC | |
| Tgene | BAZ1B | chr16:21964777 | chr7:72892899 | ENST00000339594 | 5 | 20 | 207_213 | 297 | 1852.6666666666667 | Motif | Note=C motif | |
| Tgene | BAZ1B | chr16:21964777 | chr7:72892899 | ENST00000404251 | 5 | 19 | 207_213 | 297 | 1484.0 | Motif | Note=C motif |
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Fusion Gene Sequence for UQCRC2-BAZ1B |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >97007_97007_1_UQCRC2-BAZ1B_UQCRC2_chr16_21964777_ENST00000268379_BAZ1B_chr7_72892899_ENST00000339594_length(transcript)=5669nt_BP=797nt ACTATCCAAAACATTTCTATTTTCCTAACACAAAAACTATAGCTAAGTTTTTATATTCTATGTAGCCCCAGCCTAGGACGTAAATTCCAC GAGACCAAAAGCCTTGTGATGATTCCCCGAGGTTGCTGACCCTCCCGGTGTGTCCCGGGCCTGCTCTGGGGGACACAGCGGCGAATACGT TGAACGAGGCCCCTGTTTCACGGAGCTAAAGATCCAGTAAGGACTTCACCCAGCGAGAGGCAACTACGCCGGGCTTCGATACCCAATACC TCTGCAGAAAGGTGGAGTGGCAGGAATCTCCTGAAGCCTCCAACGTCCAGGAACGCGGAAACCCAGGGCCTCCAGTGCAGGTGTCATCCC GGAGGGCGCATGCGGAGTCCCAAGAGAGGCGCGTCCCATTGGACAATGCTGAGCGGAAGAGCCCAAGATAGCGGGGGGAGTTGTGACAGG CTGCTGCAGACGTACTTAGAAAAGGGGTGCATACTGGATATTCAGGCTAGGAGAAGAACGCAAAAAGCAGTGACGTACATTATTCTCTGC ATATATTTACTTGGGAAATTGTGCGTCTCCCTATTCTGAGTCTTGGAGGAATTGGACTGGTCCAACCTTATAAAGAGAGCAGTAGAGCGC GGCAGTATAGAGAGTACCTCACGAAGGGGACGTGGGAAAGTGTTAGCGGGGAACGCTGGGAAACTCCCGGCCTCCGCCACCATCTTGCTT TCCTTTAATCCGGCAGTGACCGTGTGTCAGAACAATCTTGAATCATGAAGCTACTAACCAGAGCCGGCTCTTTCTCGTATATGACTCTCA ACCCTTCTACTAAGAGGAAGAATACTGGATCCCCAGACAGGAAGCCCTCAAAGAAATCCAAGACAGACAACTCTTCTCTTAGTTCACCAC TAAATCCTAAGTTATGGTGTCACGTACACTTGAAGAAGTCATTGAGTGGCTCGCCACTCAAAGTGAAGAACTCAAAGAATTCCAAATCTC CTGAAGAACATCTAGAAGAAATGATGAAGATGATGTCGCCCAATAAGCTGCACACTAACTTTCACATTCCTAAAAAAGGCCCACCTGCCA AGAAACCAGGGAAGCACAGTGACAAGCCTTTGAAGGCAAAGGGCAGAAGCAAAGGCATCCTGAATGGACAGAAATCCACAGGGAATTCCA AATCTCCCAAAAAAGGACTGAAGACTCCTAAAACCAAAATGAAGCAGATGACTTTGTTGGATATGGCCAAAGGCACGCAGAAGATGACAC GAGCCCCACGGAATTCTGGGGGTACACCTAGGACCTCTAGTAAACCTCATAAACATCTGCCTCCTGCAGCCCTACACCTCATTGCATACT ACAAAGAAAACAAAGACAGGGAGGACAAGAGGAGCGCCCTGTCCTGTGTTATCTCCAAAACAGCTCGTCTTCTCTCTAGTGAAGATAGAG CTCGTCTCCCAGAAGAATTGCGAAGTCTTGTTCAAAAACGCTATGAACTTCTAGAGCACAAAAAGAGGTGGGCTTCTATGTCTGAAGAAC AACGGAAAGAATATTTGAAAAAGAAACGGGAGGAGCTGAAAAAGAAGTTGAAGGAAAAAGCCAAAGAACGAAGAGAGAAAGAAATGCTTG AGAGATTAGAAAAACAGAAGCGGTATGAGGACCAAGAGTTAACTGGCAAAAACCTTCCAGCATTCAGATTGGTGGATACCCCTGAAGGGC TGCCCAACACGCTGTTTGGGGATGTGGCCATGGTGGTGGAATTCTTGAGCTGTTATTCTGGGCTACTTTTACCAGATGCTCAGTATCCTA TTACTGCTGTGTCCCTTATGGAAGCCTTGAGTGCAGATAAGGGTGGCTTTTTATACCTTAACAGGGTGTTGGTCATCCTCTTACAGACCC TCCTACAAGATGAGATAGCAGAAGACTATGGTGAATTGGGAATGAAGCTGTCGGAAATCCCCTTGACTCTGCATTCTGTTTCAGAGCTGG TGCGGCTCTGCTTGCGCAGATCTGATGTTCAGGAGGAAAGCGAGGGCTCAGACACAGATGACAATAAAGATTCAGCTGCATTTGAGGATA ATGAGGTACAAGATGAGTTCCTAGAAAAGCTGGAGACCTCTGAATTTTTTGAGCTGACGTCAGAGGAGAAGCTACAGATCTTGACAGCAC TGTGCCACCGGATCCTCATGACATACTCAGTGCAAGACCACATGGAGACCAGACAGCAGATGTCTGCAGAGTTGTGGAAGGAACGGCTTG CTGTGTTGAAGGAAGAAAATGATAAGAAGAGAGCAGAGAAACAGAAACGGAAAGAAATGGAAGCCAAAAATAAAGAAAATGGAAAAGTTG AGAATGGGTTAGGCAAAACTGATAGGAAAAAAGAAATTGTGAAGTTTGAGCCCCAAGTAGATACAGAAGCTGAAGACATGATTAGTGCTG TGAAGAGCAGAAGGTTGCTTGCCATTCAAGCTAAGAAGGAACGGGAAATCCAGGAAAGAGAAATGAAAGTGAAACTGGAACGCCAAGCTG AAGAAGAACGAATACGGAAGCACAAAGCAGCTGCTGAGAAAGCTTTCCAGGAAGGGATTGCCAAGGCCAAACTAGTCATGCGCAGGACTC CTATTGGCACAGATCGAAACCATAATAGATACTGGCTCTTCTCAGATGAAGTTCCAGGATTATTCATTGAAAAAGGCTGGGTACATGACA GCATTGACTACCGATTCAACCATCACTGCAAAGACCACACAGTCTCTGGTGATGAGGATTACTGTCCTCGCAGTAAGAAAGCAAACTTAG GTAAAAATGCAAGCATGAACACACAACATGGAACAGCAACAGAAGTTGCTGTAGAGACAACCACACCCAAACAAGGACAGAACCTATGGT TTTTATGTGATAGTCAAAAGGAGCTGGATGAGTTGCTAAACTGTCTTCACCCTCAGGGAATAAGAGAAAGTCAACTTAAAGAGAGACTAG AGAAGAGGTACCAGGACATTATTCACTCTATTCATCTAGCACGGAAGCCAAATTTGGGTCTAAAATCTTGTGATGGCAACCAGGAGCTTT TAAACTTCCTTCGTAGTGATCTCATTGAAGTTGCAACAAGGTTACAAAAAGGAGGACTTGGATATGTGGAAGAAACATCAGAATTTGAAG CCCGGGTCATTTCATTAGAGAAATTGAAGGATTTTGGTGAGTGTGTGATTGCCCTTCAGGCCAGTGTCATAAAGAAATTTCTCCAAGGCT TCATGGCTCCCAAGCAAAAGAGAAGAAAACTCCAAAGTGAAGATTCAGCAAAAACTGAGGAAGTGGATGAAGAGAAGAAAATGGTAGAGG AAGCAAAGGTTGCATCTGCACTGGAGAAATGGAAGACAGCAATCCGGGAAGCTCAGACTTTCTCCAGGATGCACGTGCTGCTTGGGATGC TTGATGCCTGTATCAAGTGGGATATGTCCGCAGAAAATGCTAGGTGCAAAGTTTGTCGAAAGAAAGGTGAGGATGACAAATTGATCTTGT GTGATGAGTGTAATAAAGCCTTCCACCTGTTTTGTCTGAGGCCGGCCCTCTATGAAGTACCAGATGGTGAGTGGCAGTGCCCAGCTTGCC AGCCCGCTACTGCCAGGCGCAACTCCCGTGGCAGGAACTATACTGAAGAGTCTGCTTCTGAGGACAGTGAAGATGATGAGAGTGATGAAG AGGAGGAGGAGGAAGAAGAGGAGGAGGAGGAAGAAGATTATGAGGTGGCTGGTTTGCGATTGAGACCTCGAAAGACCATCCGGGGCAAGC ACAGCGTCATCCCCCCTGCAGCAAGGTCAGGCCGGCGCCCGGGTAAGAAGCCACACTCTACCAGGAGGTCTCAGCCCAAGGCACCACCTG TGGATGATGCTGAGGTGGATGAGCTGGTGCTTCAGACCAAGCGGAGCTCCCGGAGGCAAAGCCTGGAGCTGCAGAAGTGTGAAGAGATCC TCCACAAGATCGTGAAGTACCGCTTCAGCTGGCCCTTCAGGGAGCCTGTGACCAGAGATGAGGCCGAGGACTACTATGATGTGATCACGC ACCCCATGGACTTTCAGACAGTGCAGAACAAATGTTCCTGTGGGAGCTACCGCTCTGTGCAGGAGTTTCTTACTGACATGAAGCAAGTGT TTACCAATGCTGAGGTTTACAACTGCCGTGGCAGCCATGTGCTAAGCTGCATGGTGAAGACAGAACAGTGTCTAGTGGCTCTGTTGCATA AACACCTTCCTGGCCACCCATATGTCCGCAGGAAGCGCAAGAAGTTTCCTGATAGGCTTGCTGAAGATGAAGGGGACAGTGAGCCAGAGG CCGTTGGACAGTCCAGGGGACGAAGACAGAAGAAGTAGAGAGGCAGGGCCGTGGTGACAGTATCAGTGAGTGCCATACAGAATTGTGTAT TCACCAGCATCATGAAACAGTTGTGGTCTTTTGAGTTGATCTTGGCAGAGTAAAGGGACGTGTCCTGGAGCCATTCCTGAATCTCCCCTT CTTTGTGACAGCTCCTCCCACCCCCCCAAAAAATAAAAAAACCACAAAAAACAAAAAAACAAAACTAAGGCACTTCACTTAGAGACTGGA GTCCTGCTTATAATCATGCATATAACCTTTACTTTGATGGATCTGGCCAGAGGGGTGTTGGAGCCCAGCCCACCCACATACCAGTCAAGC TCTTAGGGGAGCAGAAGAAAAGCAGGAAGAATTTAAATGTTTAATTTTTTTTTTAAATTGACTTTTCTAGTTATTAAAAGTTGCTTGTTT CAGCAGTGATATTGTATAAAGAACATCTTGTAAGATACTCCTGACATCTTGCTTTAGCACATGTACAGTACAGTTTCTATGATAATGTGT TTGCTCTAACTTCCCTGGCTTCTCCTTCAGCCCATCCACTCTCCTCTAGAGCAGTTGGGTTGGAGGCTCATTGAGGCAAGCAGCAACATT GGAGGGGGAGCAGGGCAGTGCTGTGTCTGCTGCCTCCCATGCCCGTTCTGACCTCAGCCTTGGAACTCCTCAAGAACCTGAAGATTCCAG TGGTCAGTGTCGGTGGGGGGTGGGAGGAGAGAGCGGCAGAGAAGCTCTGAGAGCCCCTTCCCCCACAACAAATCTAGCTCTAGTTGTTAT ATTTAGGCAAAACTTTGTAGTCTTCTTTCCCTTTTATGATGGATTTTGATAAAAGTACAAAACAGGGTTTTTCTTTTTTATCACCTTTGA ATTTGGAAATTTTGAGCACCCAAGCTCTTCTGTACCTATTTAAAGTCCACCAAGGGGACTGCAGCTCCTAGAACATGAGAATCAAGCCTC TTAATTTTAAACTGCGGAATGTGGCCTCTGCTTCCTCCGTCCTCCTGCCCAAGGACGACGAGGATTGCTCCAGGGCTGCTGGGTAGTTTA CCGTCCCTTCTATAGGCATGGAGTTGGCACTGACATCACAGCTTCATAACCCCACCACCGCCAGCTTCCCCTGCCTCCTACATCCAGTCT GTTCTTGTTCATAGTGAGAATCCTGTGTTCCCACTTCAGTGACACCTGAATTGTTTGTTGTTGTTTTTTTTTTTTATTGTCTTCAAAGAG >97007_97007_1_UQCRC2-BAZ1B_UQCRC2_chr16_21964777_ENST00000268379_BAZ1B_chr7_72892899_ENST00000339594_length(amino acids)=1197AA_BP=9 MKLLTRAGSFSYMTLNPSTKRKNTGSPDRKPSKKSKTDNSSLSSPLNPKLWCHVHLKKSLSGSPLKVKNSKNSKSPEEHLEEMMKMMSPN KLHTNFHIPKKGPPAKKPGKHSDKPLKAKGRSKGILNGQKSTGNSKSPKKGLKTPKTKMKQMTLLDMAKGTQKMTRAPRNSGGTPRTSSK PHKHLPPAALHLIAYYKENKDREDKRSALSCVISKTARLLSSEDRARLPEELRSLVQKRYELLEHKKRWASMSEEQRKEYLKKKREELKK KLKEKAKERREKEMLERLEKQKRYEDQELTGKNLPAFRLVDTPEGLPNTLFGDVAMVVEFLSCYSGLLLPDAQYPITAVSLMEALSADKG GFLYLNRVLVILLQTLLQDEIAEDYGELGMKLSEIPLTLHSVSELVRLCLRRSDVQEESEGSDTDDNKDSAAFEDNEVQDEFLEKLETSE FFELTSEEKLQILTALCHRILMTYSVQDHMETRQQMSAELWKERLAVLKEENDKKRAEKQKRKEMEAKNKENGKVENGLGKTDRKKEIVK FEPQVDTEAEDMISAVKSRRLLAIQAKKEREIQEREMKVKLERQAEEERIRKHKAAAEKAFQEGIAKAKLVMRRTPIGTDRNHNRYWLFS DEVPGLFIEKGWVHDSIDYRFNHHCKDHTVSGDEDYCPRSKKANLGKNASMNTQHGTATEVAVETTTPKQGQNLWFLCDSQKELDELLNC LHPQGIRESQLKERLEKRYQDIIHSIHLARKPNLGLKSCDGNQELLNFLRSDLIEVATRLQKGGLGYVEETSEFEARVISLEKLKDFGEC VIALQASVIKKFLQGFMAPKQKRRKLQSEDSAKTEEVDEEKKMVEEAKVASALEKWKTAIREAQTFSRMHVLLGMLDACIKWDMSAENAR CKVCRKKGEDDKLILCDECNKAFHLFCLRPALYEVPDGEWQCPACQPATARRNSRGRNYTEESASEDSEDDESDEEEEEEEEEEEEEDYE VAGLRLRPRKTIRGKHSVIPPAARSGRRPGKKPHSTRRSQPKAPPVDDAEVDELVLQTKRSSRRQSLELQKCEEILHKIVKYRFSWPFRE PVTRDEAEDYYDVITHPMDFQTVQNKCSCGSYRSVQEFLTDMKQVFTNAEVYNCRGSHVLSCMVKTEQCLVALLHKHLPGHPYVRRKRKK -------------------------------------------------------------- >97007_97007_2_UQCRC2-BAZ1B_UQCRC2_chr16_21964777_ENST00000268379_BAZ1B_chr7_72892899_ENST00000404251_length(transcript)=4989nt_BP=797nt ACTATCCAAAACATTTCTATTTTCCTAACACAAAAACTATAGCTAAGTTTTTATATTCTATGTAGCCCCAGCCTAGGACGTAAATTCCAC GAGACCAAAAGCCTTGTGATGATTCCCCGAGGTTGCTGACCCTCCCGGTGTGTCCCGGGCCTGCTCTGGGGGACACAGCGGCGAATACGT TGAACGAGGCCCCTGTTTCACGGAGCTAAAGATCCAGTAAGGACTTCACCCAGCGAGAGGCAACTACGCCGGGCTTCGATACCCAATACC TCTGCAGAAAGGTGGAGTGGCAGGAATCTCCTGAAGCCTCCAACGTCCAGGAACGCGGAAACCCAGGGCCTCCAGTGCAGGTGTCATCCC GGAGGGCGCATGCGGAGTCCCAAGAGAGGCGCGTCCCATTGGACAATGCTGAGCGGAAGAGCCCAAGATAGCGGGGGGAGTTGTGACAGG CTGCTGCAGACGTACTTAGAAAAGGGGTGCATACTGGATATTCAGGCTAGGAGAAGAACGCAAAAAGCAGTGACGTACATTATTCTCTGC ATATATTTACTTGGGAAATTGTGCGTCTCCCTATTCTGAGTCTTGGAGGAATTGGACTGGTCCAACCTTATAAAGAGAGCAGTAGAGCGC GGCAGTATAGAGAGTACCTCACGAAGGGGACGTGGGAAAGTGTTAGCGGGGAACGCTGGGAAACTCCCGGCCTCCGCCACCATCTTGCTT TCCTTTAATCCGGCAGTGACCGTGTGTCAGAACAATCTTGAATCATGAAGCTACTAACCAGAGCCGGCTCTTTCTCGTATATGACTCTCA ACCCTTCTACTAAGAGGAAGAATACTGGATCCCCAGACAGGAAGCCCTCAAAGAAATCCAAGACAGACAACTCTTCTCTTAGTTCACCAC TAAATCCTAAGTTATGGTGTCACGTACACTTGAAGAAGTCATTGAGTGGCTCGCCACTCAAAGTGAAGAACTCAAAGAATTCCAAATCTC CTGAAGAACATCTAGAAGAAATGATGAAGATGATGTCGCCCAATAAGCTGCACACTAACTTTCACATTCCTAAAAAAGGCCCACCTGCCA AGAAACCAGGGAAGCACAGTGACAAGCCTTTGAAGGCAAAGGGCAGAAGCAAAGGCATCCTGAATGGACAGAAATCCACAGGGAATTCCA AATCTCCCAAAAAAGGACTGAAGACTCCTAAAACCAAAATGAAGCAGATGACTTTGTTGGATATGGCCAAAGGCACGCAGAAGATGACAC GAGCCCCACGGAATTCTGGGGGTACACCTAGGACCTCTAGTAAACCTCATAAACATCTGCCTCCTGCAGCCCTACACCTCATTGCATACT ACAAAGAAAACAAAGACAGGGAGGACAAGAGGAGCGCCCTGTCCTGTGTTATCTCCAAAACAGCTCGTCTTCTCTCTAGTGAAGATAGAG CTCGTCTCCCAGAAGAATTGCGAAGTCTTGTTCAAAAACGCTATGAACTTCTAGAGCACAAAAAGAGGTGGGCTTCTATGTCTGAAGAAC AACGGAAAGAATATTTGAAAAAGAAACGGGAGGAGCTGAAAAAGAAGTTGAAGGAAAAAGCCAAAGAACGAAGAGAGAAAGAAATGCTTG AGAGATTAGAAAAACAGAAGCGGTATGAGGACCAAGAGTTAACTGGCAAAAACCTTCCAGCATTCAGATTGGTGGATACCCCTGAAGGGC TGCCCAACACGCTGTTTGGGGATGTGGCCATGGTGGTGGAATTCTTGAGCTGTTATTCTGGGCTACTTTTACCAGATGCTCAGTATCCTA TTACTGCTGTGTCCCTTATGGAAGCCTTGAGTGCAGATAAGGGTGGCTTTTTATACCTTAACAGGGTGTTGGTCATCCTCTTACAGACCC TCCTACAAGATGAGATAGCAGAAGACTATGGTGAATTGGGAATGAAGCTGTCGGAAATCCCCTTGACTCTGCATTCTGTTTCAGAGCTGG TGCGGCTCTGCTTGCGCAGATCTGATGTTCAGGAGGAAAGCGAGGGCTCAGACACAGATGACAATAAAGATTCAGCTGCATTTGAGGATA ATGAGGTACAAGATGAGTTCCTAGAAAAGCTGGAGACCTCTGAATTTTTTGAGCTGACGTCAGAGGAGAAGCTACAGATCTTGACAGCAC TGTGCCACCGGATCCTCATGACATACTCAGTGCAAGACCACATGGAGACCAGACAGCAGATGTCTGCAGAGTTGTGGAAGGAACGGCTTG CTGTGTTGAAGGAAGAAAATGATAAGAAGAGAGCAGAGAAACAGAAACGGAAAGAAATGGAAGCCAAAAATAAAGAAAATGGAAAAGTTG AGAATGGGTTAGGCAAAACTGATAGGAAAAAAGAAATTGTGAAGTTTGAGCCCCAAGTAGATACAGAAGCTGAAGACATGATTAGTGCTG TGAAGAGCAGAAGGTTGCTTGCCATTCAAGCTAAGAAGGAACGGGAAATCCAGGAAAGAGAAATGAAAGTGAAACTGGAACGCCAAGCTG AAGAAGAACGAATACGGAAGCACAAAGCAGCTGCTGAGAAAGCTTTCCAGGAAGGGATTGCCAAGGCCAAACTAGTCATGCGCAGGACTC CTATTGGCACAGATCGAAACCATAATAGATACTGGCTCTTCTCAGATGAAGTTCCAGGATTATTCATTGAAAAAGGCTGGGTACATGACA GCATTGACTACCGATTCAACCATCACTGCAAAGACCACACAGTCTCTGGTGATGAGGATTACTGTCCTCGCAGTAAGAAAGCAAACTTAG GTAAAAATGCAAGCATGAACACACAACATGGAACAGCAACAGAAGTTGCTGTAGAGACAACCACACCCAAACAAGGACAGAACCTATGGT TTTTATGTGATAGTCAAAAGGAGCTGGATGAGTTGCTAAACTGTCTTCACCCTCAGGGAATAAGAGAAAGTCAACTTAAAGAGAGACTAG AGAAGAGGTACCAGGACATTATTCACTCTATTCATCTAGCACGGAAGCCAAATTTGGGTCTAAAATCTTGTGATGGCAACCAGGAGCTTT TAAACTTCCTTCGTAGTGATCTCATTGAAGTTGCAACAAGGTTACAAAAAGGAGGACTTGGATATGTGGAAGAAACATCAGAATTTGAAG CCCGGGTCATTTCATTAGAGAAATTGAAGGATTTTGGTGAGTGTGTGATTGCCCTTCAGGCCAGTGTCATAAAGAAATTTCTCCAAGGCT TCATGGCTCCCAAGCAAAAGAGAAGAAAACTCCAAAGTGAAGATTCAGCAAAAACTGAGGAAGTGGATGAAGAGAAGAAAATGGTAGAGG AAGCAAAGGTTGCATCTGCACTGGAGAAATGGAAGACAGCAATCCGGGAAGCTCAGACTTTCTCCAGGATGCACGTGCTGCTTGGGATGC TTGATGCCTGTATCAAGTGGGATATGTCCGCAGAAAATGCTAGGTGCAAAGTTTGTCGAAAGAAAGGTGAGGATGACAAATTGATCTTGT GTGATGAGTGTAATAAAGCCTTCCACCTGTTTTGTCTGAGGCCGGCCCTCTATGAAGTACCAGATGGTGAGTGGCAGTGCCCAGCTTGCC AGCCCGCTACTGCCAGGCGCAACTCCCGTGGCAGGAACTATACTGAAGAGTCTGCTTCTGAGGACAGTGAAGATGATGAGAGTGATGAAG AGGAGGAGGAGGAAGAAGAGGAGGAGGAGGAAGAAGATTATGAGGTGGCTGGTTTGCGATTGAGACCTCGAAAGACCATCCGGGGCAAGC ACAGCGTCATCCCCCCTGCAGCAAGGTCAGGCCGGCGCCCGGGTAAGAAGCCACACTCTACCAGGAGGTCTCAGCCCAAGGCACCACCTG TGGATGATGCTGAGGTGGATGAGCTGGTGCTTCAGACCAAGCGGAGCTCCCGGAGGCAAAGCCTGGAGCTGCAGAAGTGTGAAGAGATCC TCCACAAGATCGTGAAGTACCGCTTCAGCTGGCCCTTCAGGGAGCCTGTGACCAGAGATGAGGCCGAGGACTACTATGATGTGATCACGC ACCCCATGGACTTTCAGACAGTGCAGAACAAATGTTCCTGTGGGAGCTACCGCTCTGTGCAGGAGTTTCTTACTGACATGAAGCAAGTGT TTACCAATGCTGAGGTTTACAACTGCCGTGGCAGCCATGTGCTAAGCTGCATGGTGAAGACAGAACAGTGTCTAGTGGCTCTGTTGCATA AACACCTTCCTGGCCACCCATATGTCCGCAGGAAGCGCAAGAAGTTTCCTGATAGGCTTGCTGAAGATGAAGGGGACAGTGAGCCAGAGG CCGTTGGACAGTCCAGGGGACGAAGACAGAAGAAGTAGAGAGGCAGGGCCGTGGTAAGGGAGCTGAGGTGGGGGGACAGCTAGGGAGGGT GGGAGGGAGGCGAGCGAGGAAGACCAAGAACCTGGAAGAGATCACAGGGAGTCCAGAAACGCCTGTCATCCCAAGCTTATGCTGTTTTTC TAAAAGCTCTTTATGGGGCTTGATATTGGGTTGGTGGTCTTTGTCCAGAAATATGAAGGGACAAAGAGGGCCATAACCCTCCCTTCTGAG AGTTTCCAGGAGGAGTCCGAGGGTCTAGCTTTTCTGGTGAAGCCAGTTCCTGTTCCTGCCTTCTTTCCTAAGGGCCTGCTCGCTCTGGCT TCCACCACAGTGCCAAGCCCCTCTGGTCTCCAGGGGAGGGATTGCTGTGTTACATAGCAGGATCGGGGTAATCAGGCCAACAGGGGAGAT GGTGGCGATTTTTCTTTTTTAATCTGTATTTATTATACAGTCTTGTTTCTTTAAGCCCATACTCTGTCTCTTCCCCCGTCTTCCTCTCAG GTGACAGTATCAGTGAGTGCCATACAGAATTGTGTATTCACCAGCATCATGAAACAGTTGTGGTCTTTTGAGTTGATCTTGGCAGAGTAA >97007_97007_2_UQCRC2-BAZ1B_UQCRC2_chr16_21964777_ENST00000268379_BAZ1B_chr7_72892899_ENST00000404251_length(amino acids)=1197AA_BP=9 MKLLTRAGSFSYMTLNPSTKRKNTGSPDRKPSKKSKTDNSSLSSPLNPKLWCHVHLKKSLSGSPLKVKNSKNSKSPEEHLEEMMKMMSPN KLHTNFHIPKKGPPAKKPGKHSDKPLKAKGRSKGILNGQKSTGNSKSPKKGLKTPKTKMKQMTLLDMAKGTQKMTRAPRNSGGTPRTSSK PHKHLPPAALHLIAYYKENKDREDKRSALSCVISKTARLLSSEDRARLPEELRSLVQKRYELLEHKKRWASMSEEQRKEYLKKKREELKK KLKEKAKERREKEMLERLEKQKRYEDQELTGKNLPAFRLVDTPEGLPNTLFGDVAMVVEFLSCYSGLLLPDAQYPITAVSLMEALSADKG GFLYLNRVLVILLQTLLQDEIAEDYGELGMKLSEIPLTLHSVSELVRLCLRRSDVQEESEGSDTDDNKDSAAFEDNEVQDEFLEKLETSE FFELTSEEKLQILTALCHRILMTYSVQDHMETRQQMSAELWKERLAVLKEENDKKRAEKQKRKEMEAKNKENGKVENGLGKTDRKKEIVK FEPQVDTEAEDMISAVKSRRLLAIQAKKEREIQEREMKVKLERQAEEERIRKHKAAAEKAFQEGIAKAKLVMRRTPIGTDRNHNRYWLFS DEVPGLFIEKGWVHDSIDYRFNHHCKDHTVSGDEDYCPRSKKANLGKNASMNTQHGTATEVAVETTTPKQGQNLWFLCDSQKELDELLNC LHPQGIRESQLKERLEKRYQDIIHSIHLARKPNLGLKSCDGNQELLNFLRSDLIEVATRLQKGGLGYVEETSEFEARVISLEKLKDFGEC VIALQASVIKKFLQGFMAPKQKRRKLQSEDSAKTEEVDEEKKMVEEAKVASALEKWKTAIREAQTFSRMHVLLGMLDACIKWDMSAENAR CKVCRKKGEDDKLILCDECNKAFHLFCLRPALYEVPDGEWQCPACQPATARRNSRGRNYTEESASEDSEDDESDEEEEEEEEEEEEEDYE VAGLRLRPRKTIRGKHSVIPPAARSGRRPGKKPHSTRRSQPKAPPVDDAEVDELVLQTKRSSRRQSLELQKCEEILHKIVKYRFSWPFRE PVTRDEAEDYYDVITHPMDFQTVQNKCSCGSYRSVQEFLTDMKQVFTNAEVYNCRGSHVLSCMVKTEQCLVALLHKHLPGHPYVRRKRKK -------------------------------------------------------------- >97007_97007_3_UQCRC2-BAZ1B_UQCRC2_chr16_21964777_ENST00000561553_BAZ1B_chr7_72892899_ENST00000339594_length(transcript)=4958nt_BP=86nt ATCTTGCTTTCCTTTAATCCGGCAGTGACCGTGTGTCAGAACAATCTTGAATCATGAAGCTACTAACCAGAGCCGGCTCTTTCTCGTATA TGACTCTCAACCCTTCTACTAAGAGGAAGAATACTGGATCCCCAGACAGGAAGCCCTCAAAGAAATCCAAGACAGACAACTCTTCTCTTA GTTCACCACTAAATCCTAAGTTATGGTGTCACGTACACTTGAAGAAGTCATTGAGTGGCTCGCCACTCAAAGTGAAGAACTCAAAGAATT CCAAATCTCCTGAAGAACATCTAGAAGAAATGATGAAGATGATGTCGCCCAATAAGCTGCACACTAACTTTCACATTCCTAAAAAAGGCC CACCTGCCAAGAAACCAGGGAAGCACAGTGACAAGCCTTTGAAGGCAAAGGGCAGAAGCAAAGGCATCCTGAATGGACAGAAATCCACAG GGAATTCCAAATCTCCCAAAAAAGGACTGAAGACTCCTAAAACCAAAATGAAGCAGATGACTTTGTTGGATATGGCCAAAGGCACGCAGA AGATGACACGAGCCCCACGGAATTCTGGGGGTACACCTAGGACCTCTAGTAAACCTCATAAACATCTGCCTCCTGCAGCCCTACACCTCA TTGCATACTACAAAGAAAACAAAGACAGGGAGGACAAGAGGAGCGCCCTGTCCTGTGTTATCTCCAAAACAGCTCGTCTTCTCTCTAGTG AAGATAGAGCTCGTCTCCCAGAAGAATTGCGAAGTCTTGTTCAAAAACGCTATGAACTTCTAGAGCACAAAAAGAGGTGGGCTTCTATGT CTGAAGAACAACGGAAAGAATATTTGAAAAAGAAACGGGAGGAGCTGAAAAAGAAGTTGAAGGAAAAAGCCAAAGAACGAAGAGAGAAAG AAATGCTTGAGAGATTAGAAAAACAGAAGCGGTATGAGGACCAAGAGTTAACTGGCAAAAACCTTCCAGCATTCAGATTGGTGGATACCC CTGAAGGGCTGCCCAACACGCTGTTTGGGGATGTGGCCATGGTGGTGGAATTCTTGAGCTGTTATTCTGGGCTACTTTTACCAGATGCTC AGTATCCTATTACTGCTGTGTCCCTTATGGAAGCCTTGAGTGCAGATAAGGGTGGCTTTTTATACCTTAACAGGGTGTTGGTCATCCTCT TACAGACCCTCCTACAAGATGAGATAGCAGAAGACTATGGTGAATTGGGAATGAAGCTGTCGGAAATCCCCTTGACTCTGCATTCTGTTT CAGAGCTGGTGCGGCTCTGCTTGCGCAGATCTGATGTTCAGGAGGAAAGCGAGGGCTCAGACACAGATGACAATAAAGATTCAGCTGCAT TTGAGGATAATGAGGTACAAGATGAGTTCCTAGAAAAGCTGGAGACCTCTGAATTTTTTGAGCTGACGTCAGAGGAGAAGCTACAGATCT TGACAGCACTGTGCCACCGGATCCTCATGACATACTCAGTGCAAGACCACATGGAGACCAGACAGCAGATGTCTGCAGAGTTGTGGAAGG AACGGCTTGCTGTGTTGAAGGAAGAAAATGATAAGAAGAGAGCAGAGAAACAGAAACGGAAAGAAATGGAAGCCAAAAATAAAGAAAATG GAAAAGTTGAGAATGGGTTAGGCAAAACTGATAGGAAAAAAGAAATTGTGAAGTTTGAGCCCCAAGTAGATACAGAAGCTGAAGACATGA TTAGTGCTGTGAAGAGCAGAAGGTTGCTTGCCATTCAAGCTAAGAAGGAACGGGAAATCCAGGAAAGAGAAATGAAAGTGAAACTGGAAC GCCAAGCTGAAGAAGAACGAATACGGAAGCACAAAGCAGCTGCTGAGAAAGCTTTCCAGGAAGGGATTGCCAAGGCCAAACTAGTCATGC GCAGGACTCCTATTGGCACAGATCGAAACCATAATAGATACTGGCTCTTCTCAGATGAAGTTCCAGGATTATTCATTGAAAAAGGCTGGG TACATGACAGCATTGACTACCGATTCAACCATCACTGCAAAGACCACACAGTCTCTGGTGATGAGGATTACTGTCCTCGCAGTAAGAAAG CAAACTTAGGTAAAAATGCAAGCATGAACACACAACATGGAACAGCAACAGAAGTTGCTGTAGAGACAACCACACCCAAACAAGGACAGA ACCTATGGTTTTTATGTGATAGTCAAAAGGAGCTGGATGAGTTGCTAAACTGTCTTCACCCTCAGGGAATAAGAGAAAGTCAACTTAAAG AGAGACTAGAGAAGAGGTACCAGGACATTATTCACTCTATTCATCTAGCACGGAAGCCAAATTTGGGTCTAAAATCTTGTGATGGCAACC AGGAGCTTTTAAACTTCCTTCGTAGTGATCTCATTGAAGTTGCAACAAGGTTACAAAAAGGAGGACTTGGATATGTGGAAGAAACATCAG AATTTGAAGCCCGGGTCATTTCATTAGAGAAATTGAAGGATTTTGGTGAGTGTGTGATTGCCCTTCAGGCCAGTGTCATAAAGAAATTTC TCCAAGGCTTCATGGCTCCCAAGCAAAAGAGAAGAAAACTCCAAAGTGAAGATTCAGCAAAAACTGAGGAAGTGGATGAAGAGAAGAAAA TGGTAGAGGAAGCAAAGGTTGCATCTGCACTGGAGAAATGGAAGACAGCAATCCGGGAAGCTCAGACTTTCTCCAGGATGCACGTGCTGC TTGGGATGCTTGATGCCTGTATCAAGTGGGATATGTCCGCAGAAAATGCTAGGTGCAAAGTTTGTCGAAAGAAAGGTGAGGATGACAAAT TGATCTTGTGTGATGAGTGTAATAAAGCCTTCCACCTGTTTTGTCTGAGGCCGGCCCTCTATGAAGTACCAGATGGTGAGTGGCAGTGCC CAGCTTGCCAGCCCGCTACTGCCAGGCGCAACTCCCGTGGCAGGAACTATACTGAAGAGTCTGCTTCTGAGGACAGTGAAGATGATGAGA GTGATGAAGAGGAGGAGGAGGAAGAAGAGGAGGAGGAGGAAGAAGATTATGAGGTGGCTGGTTTGCGATTGAGACCTCGAAAGACCATCC GGGGCAAGCACAGCGTCATCCCCCCTGCAGCAAGGTCAGGCCGGCGCCCGGGTAAGAAGCCACACTCTACCAGGAGGTCTCAGCCCAAGG CACCACCTGTGGATGATGCTGAGGTGGATGAGCTGGTGCTTCAGACCAAGCGGAGCTCCCGGAGGCAAAGCCTGGAGCTGCAGAAGTGTG AAGAGATCCTCCACAAGATCGTGAAGTACCGCTTCAGCTGGCCCTTCAGGGAGCCTGTGACCAGAGATGAGGCCGAGGACTACTATGATG TGATCACGCACCCCATGGACTTTCAGACAGTGCAGAACAAATGTTCCTGTGGGAGCTACCGCTCTGTGCAGGAGTTTCTTACTGACATGA AGCAAGTGTTTACCAATGCTGAGGTTTACAACTGCCGTGGCAGCCATGTGCTAAGCTGCATGGTGAAGACAGAACAGTGTCTAGTGGCTC TGTTGCATAAACACCTTCCTGGCCACCCATATGTCCGCAGGAAGCGCAAGAAGTTTCCTGATAGGCTTGCTGAAGATGAAGGGGACAGTG AGCCAGAGGCCGTTGGACAGTCCAGGGGACGAAGACAGAAGAAGTAGAGAGGCAGGGCCGTGGTGACAGTATCAGTGAGTGCCATACAGA ATTGTGTATTCACCAGCATCATGAAACAGTTGTGGTCTTTTGAGTTGATCTTGGCAGAGTAAAGGGACGTGTCCTGGAGCCATTCCTGAA TCTCCCCTTCTTTGTGACAGCTCCTCCCACCCCCCCAAAAAATAAAAAAACCACAAAAAACAAAAAAACAAAACTAAGGCACTTCACTTA GAGACTGGAGTCCTGCTTATAATCATGCATATAACCTTTACTTTGATGGATCTGGCCAGAGGGGTGTTGGAGCCCAGCCCACCCACATAC CAGTCAAGCTCTTAGGGGAGCAGAAGAAAAGCAGGAAGAATTTAAATGTTTAATTTTTTTTTTAAATTGACTTTTCTAGTTATTAAAAGT TGCTTGTTTCAGCAGTGATATTGTATAAAGAACATCTTGTAAGATACTCCTGACATCTTGCTTTAGCACATGTACAGTACAGTTTCTATG ATAATGTGTTTGCTCTAACTTCCCTGGCTTCTCCTTCAGCCCATCCACTCTCCTCTAGAGCAGTTGGGTTGGAGGCTCATTGAGGCAAGC AGCAACATTGGAGGGGGAGCAGGGCAGTGCTGTGTCTGCTGCCTCCCATGCCCGTTCTGACCTCAGCCTTGGAACTCCTCAAGAACCTGA AGATTCCAGTGGTCAGTGTCGGTGGGGGGTGGGAGGAGAGAGCGGCAGAGAAGCTCTGAGAGCCCCTTCCCCCACAACAAATCTAGCTCT AGTTGTTATATTTAGGCAAAACTTTGTAGTCTTCTTTCCCTTTTATGATGGATTTTGATAAAAGTACAAAACAGGGTTTTTCTTTTTTAT CACCTTTGAATTTGGAAATTTTGAGCACCCAAGCTCTTCTGTACCTATTTAAAGTCCACCAAGGGGACTGCAGCTCCTAGAACATGAGAA TCAAGCCTCTTAATTTTAAACTGCGGAATGTGGCCTCTGCTTCCTCCGTCCTCCTGCCCAAGGACGACGAGGATTGCTCCAGGGCTGCTG GGTAGTTTACCGTCCCTTCTATAGGCATGGAGTTGGCACTGACATCACAGCTTCATAACCCCACCACCGCCAGCTTCCCCTGCCTCCTAC ATCCAGTCTGTTCTTGTTCATAGTGAGAATCCTGTGTTCCCACTTCAGTGACACCTGAATTGTTTGTTGTTGTTTTTTTTTTTTATTGTC TTCAAAGAGGAAGGGCCCCATTAAAGGGTGAACTTGTAATAAATTGGAATTTCAAATAAACCTCATGTACTTGTGTTTATAAAGAAGAAA >97007_97007_3_UQCRC2-BAZ1B_UQCRC2_chr16_21964777_ENST00000561553_BAZ1B_chr7_72892899_ENST00000339594_length(amino acids)=1197AA_BP=9 MKLLTRAGSFSYMTLNPSTKRKNTGSPDRKPSKKSKTDNSSLSSPLNPKLWCHVHLKKSLSGSPLKVKNSKNSKSPEEHLEEMMKMMSPN KLHTNFHIPKKGPPAKKPGKHSDKPLKAKGRSKGILNGQKSTGNSKSPKKGLKTPKTKMKQMTLLDMAKGTQKMTRAPRNSGGTPRTSSK PHKHLPPAALHLIAYYKENKDREDKRSALSCVISKTARLLSSEDRARLPEELRSLVQKRYELLEHKKRWASMSEEQRKEYLKKKREELKK KLKEKAKERREKEMLERLEKQKRYEDQELTGKNLPAFRLVDTPEGLPNTLFGDVAMVVEFLSCYSGLLLPDAQYPITAVSLMEALSADKG GFLYLNRVLVILLQTLLQDEIAEDYGELGMKLSEIPLTLHSVSELVRLCLRRSDVQEESEGSDTDDNKDSAAFEDNEVQDEFLEKLETSE FFELTSEEKLQILTALCHRILMTYSVQDHMETRQQMSAELWKERLAVLKEENDKKRAEKQKRKEMEAKNKENGKVENGLGKTDRKKEIVK FEPQVDTEAEDMISAVKSRRLLAIQAKKEREIQEREMKVKLERQAEEERIRKHKAAAEKAFQEGIAKAKLVMRRTPIGTDRNHNRYWLFS DEVPGLFIEKGWVHDSIDYRFNHHCKDHTVSGDEDYCPRSKKANLGKNASMNTQHGTATEVAVETTTPKQGQNLWFLCDSQKELDELLNC LHPQGIRESQLKERLEKRYQDIIHSIHLARKPNLGLKSCDGNQELLNFLRSDLIEVATRLQKGGLGYVEETSEFEARVISLEKLKDFGEC VIALQASVIKKFLQGFMAPKQKRRKLQSEDSAKTEEVDEEKKMVEEAKVASALEKWKTAIREAQTFSRMHVLLGMLDACIKWDMSAENAR CKVCRKKGEDDKLILCDECNKAFHLFCLRPALYEVPDGEWQCPACQPATARRNSRGRNYTEESASEDSEDDESDEEEEEEEEEEEEEDYE VAGLRLRPRKTIRGKHSVIPPAARSGRRPGKKPHSTRRSQPKAPPVDDAEVDELVLQTKRSSRRQSLELQKCEEILHKIVKYRFSWPFRE PVTRDEAEDYYDVITHPMDFQTVQNKCSCGSYRSVQEFLTDMKQVFTNAEVYNCRGSHVLSCMVKTEQCLVALLHKHLPGHPYVRRKRKK -------------------------------------------------------------- >97007_97007_4_UQCRC2-BAZ1B_UQCRC2_chr16_21964777_ENST00000561553_BAZ1B_chr7_72892899_ENST00000404251_length(transcript)=4278nt_BP=86nt ATCTTGCTTTCCTTTAATCCGGCAGTGACCGTGTGTCAGAACAATCTTGAATCATGAAGCTACTAACCAGAGCCGGCTCTTTCTCGTATA TGACTCTCAACCCTTCTACTAAGAGGAAGAATACTGGATCCCCAGACAGGAAGCCCTCAAAGAAATCCAAGACAGACAACTCTTCTCTTA GTTCACCACTAAATCCTAAGTTATGGTGTCACGTACACTTGAAGAAGTCATTGAGTGGCTCGCCACTCAAAGTGAAGAACTCAAAGAATT CCAAATCTCCTGAAGAACATCTAGAAGAAATGATGAAGATGATGTCGCCCAATAAGCTGCACACTAACTTTCACATTCCTAAAAAAGGCC CACCTGCCAAGAAACCAGGGAAGCACAGTGACAAGCCTTTGAAGGCAAAGGGCAGAAGCAAAGGCATCCTGAATGGACAGAAATCCACAG GGAATTCCAAATCTCCCAAAAAAGGACTGAAGACTCCTAAAACCAAAATGAAGCAGATGACTTTGTTGGATATGGCCAAAGGCACGCAGA AGATGACACGAGCCCCACGGAATTCTGGGGGTACACCTAGGACCTCTAGTAAACCTCATAAACATCTGCCTCCTGCAGCCCTACACCTCA TTGCATACTACAAAGAAAACAAAGACAGGGAGGACAAGAGGAGCGCCCTGTCCTGTGTTATCTCCAAAACAGCTCGTCTTCTCTCTAGTG AAGATAGAGCTCGTCTCCCAGAAGAATTGCGAAGTCTTGTTCAAAAACGCTATGAACTTCTAGAGCACAAAAAGAGGTGGGCTTCTATGT CTGAAGAACAACGGAAAGAATATTTGAAAAAGAAACGGGAGGAGCTGAAAAAGAAGTTGAAGGAAAAAGCCAAAGAACGAAGAGAGAAAG AAATGCTTGAGAGATTAGAAAAACAGAAGCGGTATGAGGACCAAGAGTTAACTGGCAAAAACCTTCCAGCATTCAGATTGGTGGATACCC CTGAAGGGCTGCCCAACACGCTGTTTGGGGATGTGGCCATGGTGGTGGAATTCTTGAGCTGTTATTCTGGGCTACTTTTACCAGATGCTC AGTATCCTATTACTGCTGTGTCCCTTATGGAAGCCTTGAGTGCAGATAAGGGTGGCTTTTTATACCTTAACAGGGTGTTGGTCATCCTCT TACAGACCCTCCTACAAGATGAGATAGCAGAAGACTATGGTGAATTGGGAATGAAGCTGTCGGAAATCCCCTTGACTCTGCATTCTGTTT CAGAGCTGGTGCGGCTCTGCTTGCGCAGATCTGATGTTCAGGAGGAAAGCGAGGGCTCAGACACAGATGACAATAAAGATTCAGCTGCAT TTGAGGATAATGAGGTACAAGATGAGTTCCTAGAAAAGCTGGAGACCTCTGAATTTTTTGAGCTGACGTCAGAGGAGAAGCTACAGATCT TGACAGCACTGTGCCACCGGATCCTCATGACATACTCAGTGCAAGACCACATGGAGACCAGACAGCAGATGTCTGCAGAGTTGTGGAAGG AACGGCTTGCTGTGTTGAAGGAAGAAAATGATAAGAAGAGAGCAGAGAAACAGAAACGGAAAGAAATGGAAGCCAAAAATAAAGAAAATG GAAAAGTTGAGAATGGGTTAGGCAAAACTGATAGGAAAAAAGAAATTGTGAAGTTTGAGCCCCAAGTAGATACAGAAGCTGAAGACATGA TTAGTGCTGTGAAGAGCAGAAGGTTGCTTGCCATTCAAGCTAAGAAGGAACGGGAAATCCAGGAAAGAGAAATGAAAGTGAAACTGGAAC GCCAAGCTGAAGAAGAACGAATACGGAAGCACAAAGCAGCTGCTGAGAAAGCTTTCCAGGAAGGGATTGCCAAGGCCAAACTAGTCATGC GCAGGACTCCTATTGGCACAGATCGAAACCATAATAGATACTGGCTCTTCTCAGATGAAGTTCCAGGATTATTCATTGAAAAAGGCTGGG TACATGACAGCATTGACTACCGATTCAACCATCACTGCAAAGACCACACAGTCTCTGGTGATGAGGATTACTGTCCTCGCAGTAAGAAAG CAAACTTAGGTAAAAATGCAAGCATGAACACACAACATGGAACAGCAACAGAAGTTGCTGTAGAGACAACCACACCCAAACAAGGACAGA ACCTATGGTTTTTATGTGATAGTCAAAAGGAGCTGGATGAGTTGCTAAACTGTCTTCACCCTCAGGGAATAAGAGAAAGTCAACTTAAAG AGAGACTAGAGAAGAGGTACCAGGACATTATTCACTCTATTCATCTAGCACGGAAGCCAAATTTGGGTCTAAAATCTTGTGATGGCAACC AGGAGCTTTTAAACTTCCTTCGTAGTGATCTCATTGAAGTTGCAACAAGGTTACAAAAAGGAGGACTTGGATATGTGGAAGAAACATCAG AATTTGAAGCCCGGGTCATTTCATTAGAGAAATTGAAGGATTTTGGTGAGTGTGTGATTGCCCTTCAGGCCAGTGTCATAAAGAAATTTC TCCAAGGCTTCATGGCTCCCAAGCAAAAGAGAAGAAAACTCCAAAGTGAAGATTCAGCAAAAACTGAGGAAGTGGATGAAGAGAAGAAAA TGGTAGAGGAAGCAAAGGTTGCATCTGCACTGGAGAAATGGAAGACAGCAATCCGGGAAGCTCAGACTTTCTCCAGGATGCACGTGCTGC TTGGGATGCTTGATGCCTGTATCAAGTGGGATATGTCCGCAGAAAATGCTAGGTGCAAAGTTTGTCGAAAGAAAGGTGAGGATGACAAAT TGATCTTGTGTGATGAGTGTAATAAAGCCTTCCACCTGTTTTGTCTGAGGCCGGCCCTCTATGAAGTACCAGATGGTGAGTGGCAGTGCC CAGCTTGCCAGCCCGCTACTGCCAGGCGCAACTCCCGTGGCAGGAACTATACTGAAGAGTCTGCTTCTGAGGACAGTGAAGATGATGAGA GTGATGAAGAGGAGGAGGAGGAAGAAGAGGAGGAGGAGGAAGAAGATTATGAGGTGGCTGGTTTGCGATTGAGACCTCGAAAGACCATCC GGGGCAAGCACAGCGTCATCCCCCCTGCAGCAAGGTCAGGCCGGCGCCCGGGTAAGAAGCCACACTCTACCAGGAGGTCTCAGCCCAAGG CACCACCTGTGGATGATGCTGAGGTGGATGAGCTGGTGCTTCAGACCAAGCGGAGCTCCCGGAGGCAAAGCCTGGAGCTGCAGAAGTGTG AAGAGATCCTCCACAAGATCGTGAAGTACCGCTTCAGCTGGCCCTTCAGGGAGCCTGTGACCAGAGATGAGGCCGAGGACTACTATGATG TGATCACGCACCCCATGGACTTTCAGACAGTGCAGAACAAATGTTCCTGTGGGAGCTACCGCTCTGTGCAGGAGTTTCTTACTGACATGA AGCAAGTGTTTACCAATGCTGAGGTTTACAACTGCCGTGGCAGCCATGTGCTAAGCTGCATGGTGAAGACAGAACAGTGTCTAGTGGCTC TGTTGCATAAACACCTTCCTGGCCACCCATATGTCCGCAGGAAGCGCAAGAAGTTTCCTGATAGGCTTGCTGAAGATGAAGGGGACAGTG AGCCAGAGGCCGTTGGACAGTCCAGGGGACGAAGACAGAAGAAGTAGAGAGGCAGGGCCGTGGTAAGGGAGCTGAGGTGGGGGGACAGCT AGGGAGGGTGGGAGGGAGGCGAGCGAGGAAGACCAAGAACCTGGAAGAGATCACAGGGAGTCCAGAAACGCCTGTCATCCCAAGCTTATG CTGTTTTTCTAAAAGCTCTTTATGGGGCTTGATATTGGGTTGGTGGTCTTTGTCCAGAAATATGAAGGGACAAAGAGGGCCATAACCCTC CCTTCTGAGAGTTTCCAGGAGGAGTCCGAGGGTCTAGCTTTTCTGGTGAAGCCAGTTCCTGTTCCTGCCTTCTTTCCTAAGGGCCTGCTC GCTCTGGCTTCCACCACAGTGCCAAGCCCCTCTGGTCTCCAGGGGAGGGATTGCTGTGTTACATAGCAGGATCGGGGTAATCAGGCCAAC AGGGGAGATGGTGGCGATTTTTCTTTTTTAATCTGTATTTATTATACAGTCTTGTTTCTTTAAGCCCATACTCTGTCTCTTCCCCCGTCT TCCTCTCAGGTGACAGTATCAGTGAGTGCCATACAGAATTGTGTATTCACCAGCATCATGAAACAGTTGTGGTCTTTTGAGTTGATCTTG >97007_97007_4_UQCRC2-BAZ1B_UQCRC2_chr16_21964777_ENST00000561553_BAZ1B_chr7_72892899_ENST00000404251_length(amino acids)=1197AA_BP=9 MKLLTRAGSFSYMTLNPSTKRKNTGSPDRKPSKKSKTDNSSLSSPLNPKLWCHVHLKKSLSGSPLKVKNSKNSKSPEEHLEEMMKMMSPN KLHTNFHIPKKGPPAKKPGKHSDKPLKAKGRSKGILNGQKSTGNSKSPKKGLKTPKTKMKQMTLLDMAKGTQKMTRAPRNSGGTPRTSSK PHKHLPPAALHLIAYYKENKDREDKRSALSCVISKTARLLSSEDRARLPEELRSLVQKRYELLEHKKRWASMSEEQRKEYLKKKREELKK KLKEKAKERREKEMLERLEKQKRYEDQELTGKNLPAFRLVDTPEGLPNTLFGDVAMVVEFLSCYSGLLLPDAQYPITAVSLMEALSADKG GFLYLNRVLVILLQTLLQDEIAEDYGELGMKLSEIPLTLHSVSELVRLCLRRSDVQEESEGSDTDDNKDSAAFEDNEVQDEFLEKLETSE FFELTSEEKLQILTALCHRILMTYSVQDHMETRQQMSAELWKERLAVLKEENDKKRAEKQKRKEMEAKNKENGKVENGLGKTDRKKEIVK FEPQVDTEAEDMISAVKSRRLLAIQAKKEREIQEREMKVKLERQAEEERIRKHKAAAEKAFQEGIAKAKLVMRRTPIGTDRNHNRYWLFS DEVPGLFIEKGWVHDSIDYRFNHHCKDHTVSGDEDYCPRSKKANLGKNASMNTQHGTATEVAVETTTPKQGQNLWFLCDSQKELDELLNC LHPQGIRESQLKERLEKRYQDIIHSIHLARKPNLGLKSCDGNQELLNFLRSDLIEVATRLQKGGLGYVEETSEFEARVISLEKLKDFGEC VIALQASVIKKFLQGFMAPKQKRRKLQSEDSAKTEEVDEEKKMVEEAKVASALEKWKTAIREAQTFSRMHVLLGMLDACIKWDMSAENAR CKVCRKKGEDDKLILCDECNKAFHLFCLRPALYEVPDGEWQCPACQPATARRNSRGRNYTEESASEDSEDDESDEEEEEEEEEEEEEDYE VAGLRLRPRKTIRGKHSVIPPAARSGRRPGKKPHSTRRSQPKAPPVDDAEVDELVLQTKRSSRRQSLELQKCEEILHKIVKYRFSWPFRE PVTRDEAEDYYDVITHPMDFQTVQNKCSCGSYRSVQEFLTDMKQVFTNAEVYNCRGSHVLSCMVKTEQCLVALLHKHLPGHPYVRRKRKK -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for UQCRC2-BAZ1B |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for UQCRC2-BAZ1B |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for UQCRC2-BAZ1B |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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