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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:URI1-SLC35F1 (FusionGDB2 ID:97086)

Fusion Gene Summary for URI1-SLC35F1

check button Fusion gene summary
Fusion gene informationFusion gene name: URI1-SLC35F1
Fusion gene ID: 97086
HgeneTgene
Gene symbol

URI1

SLC35F1

Gene ID

8725

222553

Gene nameURI1 prefoldin like chaperonesolute carrier family 35 member F1
SynonymsC19orf2|NNX3|PPP1R19|RMP|URIC6orf169|dJ230I3.1
Cytomap

19q12

6q22.2-q22.31

Type of geneprotein-codingprotein-coding
Descriptionunconventional prefoldin RPB5 interactor 1RNA polymerase II subunit 5-mediating proteinRPB5-mediating proteinprotein phosphatase 1, regulatory subunit 19solute carrier family 35 member F1
Modification date2020031320200313
UniProtAcc

O94763

.
Ensembl transtripts involved in fusion geneENST00000312051, ENST00000360605, 
ENST00000392271, ENST00000542441, 
ENST00000574176, 		ENST00000360388, 
Fusion gene scores* DoF score30 X 13 X 12=468011 X 10 X 6=660
# samples 4012
** MAII scorelog2(40/4680*10)=-3.54843662469604
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(12/660*10)=-2.4594316186373
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: URI1 [Title/Abstract] AND SLC35F1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointURI1(30477324)-SLC35F1(118596622), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneURI1

GO:0000122

negative regulation of transcription by RNA polymerase II

12737519|15367675|21730289

HgeneURI1

GO:0001558

regulation of cell growth

21730289

HgeneURI1

GO:0071363

cellular response to growth factor stimulus

17936702

HgeneURI1

GO:0071383

cellular response to steroid hormone stimulus

21730289


check buttonFusion gene breakpoints across URI1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across SLC35F1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BLCATCGA-DK-AA6U-01AURI1chr19

30477324

+SLC35F1chr6

118596622

+
ChimerDB4BLCATCGA-DK-AA6UURI1chr19

30477324

+SLC35F1chr6

118596622

+


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Fusion Gene ORF analysis for URI1-SLC35F1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000312051ENST00000360388URI1chr19

30477324

+SLC35F1chr6

118596622

+
In-frameENST00000360605ENST00000360388URI1chr19

30477324

+SLC35F1chr6

118596622

+
In-frameENST00000392271ENST00000360388URI1chr19

30477324

+SLC35F1chr6

118596622

+
In-frameENST00000542441ENST00000360388URI1chr19

30477324

+SLC35F1chr6

118596622

+
intron-3CDSENST00000574176ENST00000360388URI1chr19

30477324

+SLC35F1chr6

118596622

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000360605URI1chr1930477324+ENST00000360388SLC35F1chr6118596622+437536130950306
ENST00000542441URI1chr1930477324+ENST00000360388SLC35F1chr6118596622+46786642971253318
ENST00000392271URI1chr1930477324+ENST00000360388SLC35F1chr6118596622+46786642971253318
ENST00000312051URI1chr1930477324+ENST00000360388SLC35F1chr6118596622+437636210951313

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000360605ENST00000360388URI1chr1930477324+SLC35F1chr6118596622+0.0011409880.99885905
ENST00000542441ENST00000360388URI1chr1930477324+SLC35F1chr6118596622+0.0006760550.99932396
ENST00000392271ENST00000360388URI1chr1930477324+SLC35F1chr6118596622+0.0006760550.99932396
ENST00000312051ENST00000360388URI1chr1930477324+SLC35F1chr6118596622+0.0011948430.99880517

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Fusion Genomic Features for URI1-SLC35F1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
URI1chr1930477324+SLC35F1chr6118596621+7.93E-060.99999213
URI1chr1930477324+SLC35F1chr6118596621+7.93E-060.99999213
URI1chr1930477324+SLC35F1chr6118596621+7.93E-060.99999213
URI1chr1930477324+SLC35F1chr6118596621+7.93E-060.99999213

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for URI1-SLC35F1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:30477324/chr6:118596622)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
URI1

O94763

.
FUNCTION: Involved in gene transcription regulation. Acts as a transcriptional repressor in concert with the corepressor UXT to regulate androgen receptor (AR) transcription. May act as a tumor suppressor to repress AR-mediated gene transcription and to inhibit anchorage-independent growth in prostate cancer cells. Required for cell survival in ovarian cancer cells. Together with UXT, associates with chromatin to the NKX3-1 promoter region. Antagonizes transcriptional modulation via hepatitis B virus X protein.; FUNCTION: Plays a central role in maintaining S6K1 signaling and BAD phosphorylation under normal growth conditions thereby protecting cells from potential deleterious effects of sustained S6K1 signaling. The URI1-PPP1CC complex acts as a central component of a negative feedback mechanism that counteracts excessive S6K1 survival signaling to BAD in response to growth factors. Mediates inhibition of PPP1CC phosphatase activity in mitochondria. Coordinates the regulation of nutrient-sensitive gene expression availability in a mTOR-dependent manner. Seems to be a scaffolding protein able to assemble a prefoldin-like complex that contains PFDs and proteins with roles in transcription and ubiquitination.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneSLC35F1chr19:30477324chr6:118596622ENST0000036038838221_241212409.0TransmembraneHelical
TgeneSLC35F1chr19:30477324chr6:118596622ENST0000036038838247_267212409.0TransmembraneHelical
TgeneSLC35F1chr19:30477324chr6:118596622ENST0000036038838284_304212409.0TransmembraneHelical
TgeneSLC35F1chr19:30477324chr6:118596622ENST0000036038838311_331212409.0TransmembraneHelical
TgeneSLC35F1chr19:30477324chr6:118596622ENST0000036038838335_355212409.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneURI1chr19:30477324chr6:118596622ENST00000360605+411299_311104476.0Compositional biasNote=Poly-Asp
HgeneURI1chr19:30477324chr6:118596622ENST00000360605+411314_321104476.0Compositional biasNote=Poly-Asp
HgeneURI1chr19:30477324chr6:118596622ENST00000392271+411299_31146460.0Compositional biasNote=Poly-Asp
HgeneURI1chr19:30477324chr6:118596622ENST00000392271+411314_32146460.0Compositional biasNote=Poly-Asp
HgeneURI1chr19:30477324chr6:118596622ENST00000542441+411299_311122536.0Compositional biasNote=Poly-Asp
HgeneURI1chr19:30477324chr6:118596622ENST00000542441+411314_321122536.0Compositional biasNote=Poly-Asp
TgeneSLC35F1chr19:30477324chr6:118596622ENST0000036038838129_147212409.0TransmembraneHelical
TgeneSLC35F1chr19:30477324chr6:118596622ENST0000036038838158_178212409.0TransmembraneHelical
TgeneSLC35F1chr19:30477324chr6:118596622ENST0000036038838186_206212409.0TransmembraneHelical
TgeneSLC35F1chr19:30477324chr6:118596622ENST000003603883860_80212409.0TransmembraneHelical
TgeneSLC35F1chr19:30477324chr6:118596622ENST000003603883894_114212409.0TransmembraneHelical


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Fusion Gene Sequence for URI1-SLC35F1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>97086_97086_1_URI1-SLC35F1_URI1_chr19_30477324_ENST00000312051_SLC35F1_chr6_118596622_ENST00000360388_length(transcript)=4376nt_BP=362nt
ACACGCCGCGCTGAGGCCCGCGGGCCCGTCATGGAGGCGCCCACCGTGGAGACGCCCCCCGACCCCTCGCCCCCTTCGGCCCCGGCCCCT
GCCCTGGTTCCGTTGCGCGCCCCGGATGTGGCGCGGCTGCGCGAGGAGCAGGAAAAGGAAGAAGGTAGATAATGACTATAATGCCCTTCG
AGAAAGACTCAGCACCTTGCCTGATAAATTGTCTTATAATATAATGGTACCATTTGGCCCTTTTGCCTTCATGCCAGGAAAACTTGTCCA
TACTAATGAAGTCACTGTTTTACTGGGGGACAACTGGTTTGCAAAGTGCTCAGCAAAGCAGGCTGTAGGTTTAGTTGAGCACCGGAAAGA
ACGGGAAAATAAGCTGGTAGGGGACCTTCTGGTCTTAGGAGGAGCCACACTCTATGGTATTTCTAACGTCTGGGAAGAATACATCATCCG
AACTCTGAGCCGAGTGGAATTCCTGGGAATGATTGGTCTCTTTGGAGCATTTTTCAGTGGAATTCAATTAGCTATAATGGAGCATAAGGA
ACTGTTGAAGGTGCCCTGGGACTGGCAAATAGGACTGCTCTACGTTGGCTTTAGTGCCTGCATGTTTGGTCTCTACAGCTTTATGCCAGT
CGTCATAAAGAAAACCAGTGCCACTTCAGTCAACCTCTCCTTGCTCACAGCAGACTTGTACAGCCTGTTCTGTGGATTGTTTCTCTTCCA
CTACAAGTTTTCAGGACTTTATCTCCTGTCTTTCTTCACCATCCTCATTGGGCTGGTGCTCTACTCCTCCACCTCCACCTACATAGCCCA
GGACCCCCGAGTGTATAAGCAGTTCCGCAATCCTTCAGGACCTGTTGTGGACTTACCGACCACAGCTCAGGTGGAACCCTCAGTCACCTA
CACCAGCCTGGGCCAGGAGACCGAAGAGGAGCCTCATGTTCGTGTGGCCTAGGGTGAGGCCCGCCCTGCCAACTGAGGCCAACTCATTGG
CCATGTTTTTGCCCATCATCTCTGTATTGTACATAGAGAAAGGTATTTACTAGGTGCAGTTTACACAGGTGGACTGCAAGGTAGCAAATC
CTCCAAAAGCTTGTGAAAGGAACAAGCTCAACATCACTGGAGACACAGGCTCTAATCCACCTGACTTGGAAGGATGCCTAGCTAACGTGT
ATCCTGATCACAACTCCCCTGCATTCATTACTGTGAAAATTTTTGAATCAAAAGCAAGTATTATTGTTATTATGATTTGTATTATTATTA
TTGCTGTTACTGTTATTACACCAACTTTCAGGAGGATGTTTTGTACTCCTGATGGAAACTATTGCCAGACCCACATGTAGTCAACATAAA
CCCCACTTTTCTATGGCAATTCACTTTTTAAGAGTCATACTTTATTTTTTTGCACAGACTATATGAGTGATGCATGCCACAGGAGCTCCA
CCCCTGAGAAGTTTCCTTTTCCTAGGGACCTGGTGGTTAATGGTTTCCTCTGTTACCTGTTGGATTGCCTGCTCAATAAGTATTTTGTGC
TGTGACCTTTGTGGGGAGGGGCAACTGACCATATACTTCTCTATTCTAGGAATAGATATAAAAGAAACATTTTAGCCTTTTTATATTTCG
ATCTCTGATTACTCCAGGCCATTGCCTTTCTGTTGTGCCACGTGATTCTGCTAATCAAGTCCCTGTAATAACAGGATAAGGACTGTTCCA
TTACTGTGGCTTTTGGGAGCCCCCAGAAATAATATCATTTGTGTTTAGGACAATATATAATTATAAAATCTTTCTGCTCCTCCCTGTAGC
CTCTCTTCAAAAACTATCTTTTATTTTTTTTCCAGATTTCCTTAGTGATAATATGGAAATTAATCAAGGCACTGGAAAAAGCCATGGTCC
TCTGCCCTTTTAATTCTGTGACACCTTTTTAAAAATACACCAGCATGGAAATTACCTTTATTGTGGAAAATCATTGGTTGTGCCACCTCC
TAACAAAGTCAAGGTGCTGATGTGGAGCAGTCTTTGAAAATGGCTTAATTGATTTGGCCACTTTGCAGTGGTAACAATGTCATCATTGAA
AAAGTCTGGCATTTTGGTCATATTTGGCATCCATTCAATAACAGATATATTGACACGACATTCTTTTTTTTTTTTTTTTTTTTTTTTGAG
ACGGAGTCTCACTCTGTCGCCCAGGCTGGAGTGCGGTGGCACGATCTCAGCTCACTGCAACCTCCGCCTCCGGGATTCACACCATTCTCC
TGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCACCTGCCACGACGCCCAGCTAATTTTTTGTATTTTTAGTAGAGATGGGGTTTCACC
GTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCGCCCACCTTGGCCTCCCGAAGTGCTGGGATTACAGGCGTGAGCCACTGC
GCCCGGCCGACACGACATTCTTATGGACCCAGAGAATACTGCAGGATCCTGATAAGACCTTGAGTGATATGTCACTAGTCTAATCTGTTG
CCCTTAAAATAGCCCTTTTTTCAAACACAGGAAATTAAGAAACACCACAGACCTCTATTATTTAGAATAGATTCTATGTGTCAGTATGTG
ATGTACTCTTTTAGTTTGACTGACTTCAATACCATTCAAAAAGATCCTCAATGGAGTTACAGGGTTTATAGGGGAAAAATACATGTTTAT
GAGACATTGGGCAATTCAAATCAACATGTGTTACATAAGCAAGCAAAGCAAAACACCAGTGGGGTCTCTGGAAAGTAAAAGGACAGACTA
CAGTAGAAGGACTGATCCCAGAGTGCCTGTACAAGGCCTAAATCTGGCAGGCAAAAGCATCCCACACTGTCTGTCAGCACCCACATGGCC
TTTTTGCCTGCCTTCTATAACGGGTAAGTGGACCTACCCTTGGAGATAGAGAAGAAAAATTATCTTCTCTGATATTCGGATGTAATGGTC
ATCTCAGTTCAGCCCCCTAGGAAACATGTTTTATTTTCCATGGGGAAAATATCAGCGTTAAAGCTCTATCAAATCAAAACAACTTTGCCA
ACATCTTCTCTCTGCTACCTTTTAAACCAATTAAATACCTTTCTCTGAATATTTTGTCCATTCAGATCCGAAGACCTTTAAAGACTGTGG
TTTTATTTTTGTGTTTACATTCCTTTGGTTTGAATAATTTGCTTGATTTATTGCATTTTTAGTATTTATTTTAAGCCAGATGTTTTCATC
TTTGATTCATTTTTATGACATTAATTTGTAGACACTTAGTAAAGTCTTATGAGAAGCAAGTGGATGAAATTATCTCCAAGTCCACTCAGT
AGACTGGAGTTTTTTAAAAATATAAATTTCCAAAAAGTTTGCAATCAACAGATGGCTAAAGGTTGCCATCTGAATTATTTTATAGGATAT
TTTAATTGACTCCATTGTATGGAAACCAAGTGTGAATGTTAAGATGAATTTGCCGTATACCCTTTATCATTCGGTGTCCTTGTACTCAGA
CTTTCATGTCCCTGGGTGACCTCAATGTGTTGGTTTGTCTCCATTTAGAAAGGTTGATAATATATTGAATTGTTCAAGATCAGGAGTTCC
AGACTGACCCTCCAGGAAAAAAAAAATCGCAAAGAACAAATTCTTTTTCTGTGTAAAAAACACTGATCCTTTGGGAATGGGGCGGGAAAT
GGGAGTAGGACAACATTAACTTTAGCTGTTTTAGTTTCTGAGATTTCATAACCTCAGTAGACACCAGCAAAATTTTCAGTTTCTAACTCC
ACCACCAATCTCTCCTCAATGAATAAGACTTTAGCAATTTATATAGAATTTGATCAGGTAAGAGCGAACCACAATTCTCCTGAACCCTGC
TAGAGATTAAGTGGTGGTTCTCACTTCCTCAATGAAAACTTGCACTGGGGACAGCGCTTGCCTTGGTCAGACCTTCCCACATCTACATAC
TCTCAAATACATGACCAGGTGATCAAGCAATGGAAAAATTTGCACCACCGTGTCCCATGAAATTGTTTCAATGTTTAGTTTAGATATTGC
TAACTTGTGCTATTAACCTTTTGACAAGCGTGTAGTATTGTTTGTTTTGGGTTTCTTTTTGATTTATAACTATTTAGTAGTCCCCAGCTA
GCTACCAGTACAGATTTTACCCCATGGGTAGGATTCTATTGTTAAGCCACATAACAAAGCACACTAATTCTGACAACACTGCAAATGGAA
AATACGAACCAAAAAAAAGTTACACCGATAAGTTCAACAAACTGTCCATTTTTGATATTTGCATGCTCCCCTATGGACTGGCTGTGGCAA

>97086_97086_1_URI1-SLC35F1_URI1_chr19_30477324_ENST00000312051_SLC35F1_chr6_118596622_ENST00000360388_length(amino acids)=313AA_BP=118
MRPAGPSWRRPPWRRPPTPRPLRPRPLPWFRCAPRMWRGCARSRKRKKVDNDYNALRERLSTLPDKLSYNIMVPFGPFAFMPGKLVHTNE
VTVLLGDNWFAKCSAKQAVGLVEHRKERENKLVGDLLVLGGATLYGISNVWEEYIIRTLSRVEFLGMIGLFGAFFSGIQLAIMEHKELLK
VPWDWQIGLLYVGFSACMFGLYSFMPVVIKKTSATSVNLSLLTADLYSLFCGLFLFHYKFSGLYLLSFFTILIGLVLYSSTSTYIAQDPR

--------------------------------------------------------------
>97086_97086_2_URI1-SLC35F1_URI1_chr19_30477324_ENST00000360605_SLC35F1_chr6_118596622_ENST00000360388_length(transcript)=4375nt_BP=361nt
AGTGGGTCTTCTCACTCTTTTCCAGGCTCCTTGGAGGTCACTGCCCTGATGACAACATGGTCTTCCCTTCAAGGAAGCCACGTTTCTAAG
AGGGCTCTGGCATATGCATTGGTGGTCACTAACTGCCAAGAGAGAATCCAGCATTGGAAGAAGGTAGATAATGACTATAATGCCCTTCGA
GAAAGACTCAGCACCTTGCCTGATAAATTGTCTTATAATATAATGGTACCATTTGGCCCTTTTGCCTTCATGCCAGGAAAACTTGTCCAT
ACTAATGAAGTCACTGTTTTACTGGGGGACAACTGGTTTGCAAAGTGCTCAGCAAAGCAGGCTGTAGGTTTAGTTGAGCACCGGAAAGAA
CGGGAAAATAAGCTGGTAGGGGACCTTCTGGTCTTAGGAGGAGCCACACTCTATGGTATTTCTAACGTCTGGGAAGAATACATCATCCGA
ACTCTGAGCCGAGTGGAATTCCTGGGAATGATTGGTCTCTTTGGAGCATTTTTCAGTGGAATTCAATTAGCTATAATGGAGCATAAGGAA
CTGTTGAAGGTGCCCTGGGACTGGCAAATAGGACTGCTCTACGTTGGCTTTAGTGCCTGCATGTTTGGTCTCTACAGCTTTATGCCAGTC
GTCATAAAGAAAACCAGTGCCACTTCAGTCAACCTCTCCTTGCTCACAGCAGACTTGTACAGCCTGTTCTGTGGATTGTTTCTCTTCCAC
TACAAGTTTTCAGGACTTTATCTCCTGTCTTTCTTCACCATCCTCATTGGGCTGGTGCTCTACTCCTCCACCTCCACCTACATAGCCCAG
GACCCCCGAGTGTATAAGCAGTTCCGCAATCCTTCAGGACCTGTTGTGGACTTACCGACCACAGCTCAGGTGGAACCCTCAGTCACCTAC
ACCAGCCTGGGCCAGGAGACCGAAGAGGAGCCTCATGTTCGTGTGGCCTAGGGTGAGGCCCGCCCTGCCAACTGAGGCCAACTCATTGGC
CATGTTTTTGCCCATCATCTCTGTATTGTACATAGAGAAAGGTATTTACTAGGTGCAGTTTACACAGGTGGACTGCAAGGTAGCAAATCC
TCCAAAAGCTTGTGAAAGGAACAAGCTCAACATCACTGGAGACACAGGCTCTAATCCACCTGACTTGGAAGGATGCCTAGCTAACGTGTA
TCCTGATCACAACTCCCCTGCATTCATTACTGTGAAAATTTTTGAATCAAAAGCAAGTATTATTGTTATTATGATTTGTATTATTATTAT
TGCTGTTACTGTTATTACACCAACTTTCAGGAGGATGTTTTGTACTCCTGATGGAAACTATTGCCAGACCCACATGTAGTCAACATAAAC
CCCACTTTTCTATGGCAATTCACTTTTTAAGAGTCATACTTTATTTTTTTGCACAGACTATATGAGTGATGCATGCCACAGGAGCTCCAC
CCCTGAGAAGTTTCCTTTTCCTAGGGACCTGGTGGTTAATGGTTTCCTCTGTTACCTGTTGGATTGCCTGCTCAATAAGTATTTTGTGCT
GTGACCTTTGTGGGGAGGGGCAACTGACCATATACTTCTCTATTCTAGGAATAGATATAAAAGAAACATTTTAGCCTTTTTATATTTCGA
TCTCTGATTACTCCAGGCCATTGCCTTTCTGTTGTGCCACGTGATTCTGCTAATCAAGTCCCTGTAATAACAGGATAAGGACTGTTCCAT
TACTGTGGCTTTTGGGAGCCCCCAGAAATAATATCATTTGTGTTTAGGACAATATATAATTATAAAATCTTTCTGCTCCTCCCTGTAGCC
TCTCTTCAAAAACTATCTTTTATTTTTTTTCCAGATTTCCTTAGTGATAATATGGAAATTAATCAAGGCACTGGAAAAAGCCATGGTCCT
CTGCCCTTTTAATTCTGTGACACCTTTTTAAAAATACACCAGCATGGAAATTACCTTTATTGTGGAAAATCATTGGTTGTGCCACCTCCT
AACAAAGTCAAGGTGCTGATGTGGAGCAGTCTTTGAAAATGGCTTAATTGATTTGGCCACTTTGCAGTGGTAACAATGTCATCATTGAAA
AAGTCTGGCATTTTGGTCATATTTGGCATCCATTCAATAACAGATATATTGACACGACATTCTTTTTTTTTTTTTTTTTTTTTTTTGAGA
CGGAGTCTCACTCTGTCGCCCAGGCTGGAGTGCGGTGGCACGATCTCAGCTCACTGCAACCTCCGCCTCCGGGATTCACACCATTCTCCT
GCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCACCTGCCACGACGCCCAGCTAATTTTTTGTATTTTTAGTAGAGATGGGGTTTCACCG
TGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCGCCCACCTTGGCCTCCCGAAGTGCTGGGATTACAGGCGTGAGCCACTGCG
CCCGGCCGACACGACATTCTTATGGACCCAGAGAATACTGCAGGATCCTGATAAGACCTTGAGTGATATGTCACTAGTCTAATCTGTTGC
CCTTAAAATAGCCCTTTTTTCAAACACAGGAAATTAAGAAACACCACAGACCTCTATTATTTAGAATAGATTCTATGTGTCAGTATGTGA
TGTACTCTTTTAGTTTGACTGACTTCAATACCATTCAAAAAGATCCTCAATGGAGTTACAGGGTTTATAGGGGAAAAATACATGTTTATG
AGACATTGGGCAATTCAAATCAACATGTGTTACATAAGCAAGCAAAGCAAAACACCAGTGGGGTCTCTGGAAAGTAAAAGGACAGACTAC
AGTAGAAGGACTGATCCCAGAGTGCCTGTACAAGGCCTAAATCTGGCAGGCAAAAGCATCCCACACTGTCTGTCAGCACCCACATGGCCT
TTTTGCCTGCCTTCTATAACGGGTAAGTGGACCTACCCTTGGAGATAGAGAAGAAAAATTATCTTCTCTGATATTCGGATGTAATGGTCA
TCTCAGTTCAGCCCCCTAGGAAACATGTTTTATTTTCCATGGGGAAAATATCAGCGTTAAAGCTCTATCAAATCAAAACAACTTTGCCAA
CATCTTCTCTCTGCTACCTTTTAAACCAATTAAATACCTTTCTCTGAATATTTTGTCCATTCAGATCCGAAGACCTTTAAAGACTGTGGT
TTTATTTTTGTGTTTACATTCCTTTGGTTTGAATAATTTGCTTGATTTATTGCATTTTTAGTATTTATTTTAAGCCAGATGTTTTCATCT
TTGATTCATTTTTATGACATTAATTTGTAGACACTTAGTAAAGTCTTATGAGAAGCAAGTGGATGAAATTATCTCCAAGTCCACTCAGTA
GACTGGAGTTTTTTAAAAATATAAATTTCCAAAAAGTTTGCAATCAACAGATGGCTAAAGGTTGCCATCTGAATTATTTTATAGGATATT
TTAATTGACTCCATTGTATGGAAACCAAGTGTGAATGTTAAGATGAATTTGCCGTATACCCTTTATCATTCGGTGTCCTTGTACTCAGAC
TTTCATGTCCCTGGGTGACCTCAATGTGTTGGTTTGTCTCCATTTAGAAAGGTTGATAATATATTGAATTGTTCAAGATCAGGAGTTCCA
GACTGACCCTCCAGGAAAAAAAAAATCGCAAAGAACAAATTCTTTTTCTGTGTAAAAAACACTGATCCTTTGGGAATGGGGCGGGAAATG
GGAGTAGGACAACATTAACTTTAGCTGTTTTAGTTTCTGAGATTTCATAACCTCAGTAGACACCAGCAAAATTTTCAGTTTCTAACTCCA
CCACCAATCTCTCCTCAATGAATAAGACTTTAGCAATTTATATAGAATTTGATCAGGTAAGAGCGAACCACAATTCTCCTGAACCCTGCT
AGAGATTAAGTGGTGGTTCTCACTTCCTCAATGAAAACTTGCACTGGGGACAGCGCTTGCCTTGGTCAGACCTTCCCACATCTACATACT
CTCAAATACATGACCAGGTGATCAAGCAATGGAAAAATTTGCACCACCGTGTCCCATGAAATTGTTTCAATGTTTAGTTTAGATATTGCT
AACTTGTGCTATTAACCTTTTGACAAGCGTGTAGTATTGTTTGTTTTGGGTTTCTTTTTGATTTATAACTATTTAGTAGTCCCCAGCTAG
CTACCAGTACAGATTTTACCCCATGGGTAGGATTCTATTGTTAAGCCACATAACAAAGCACACTAATTCTGACAACACTGCAAATGGAAA
ATACGAACCAAAAAAAAGTTACACCGATAAGTTCAACAAACTGTCCATTTTTGATATTTGCATGCTCCCCTATGGACTGGCTGTGGCAAT

>97086_97086_2_URI1-SLC35F1_URI1_chr19_30477324_ENST00000360605_SLC35F1_chr6_118596622_ENST00000360388_length(amino acids)=306AA_BP=111
MEVTALMTTWSSLQGSHVSKRALAYALVVTNCQERIQHWKKVDNDYNALRERLSTLPDKLSYNIMVPFGPFAFMPGKLVHTNEVTVLLGD
NWFAKCSAKQAVGLVEHRKERENKLVGDLLVLGGATLYGISNVWEEYIIRTLSRVEFLGMIGLFGAFFSGIQLAIMEHKELLKVPWDWQI
GLLYVGFSACMFGLYSFMPVVIKKTSATSVNLSLLTADLYSLFCGLFLFHYKFSGLYLLSFFTILIGLVLYSSTSTYIAQDPRVYKQFRN

--------------------------------------------------------------
>97086_97086_3_URI1-SLC35F1_URI1_chr19_30477324_ENST00000392271_SLC35F1_chr6_118596622_ENST00000360388_length(transcript)=4678nt_BP=664nt
GCGGCCGCCACGCGACGCCTGGCTGGGCCCGCACCGGAGAGGCGTCTCGGTACCTGGCAGGCGGCCTGCTACTCGGAGCCCGCTGCGGGG
CGGCGGCGGCGGGGACATGCACGTGTGAGATGCGGCAGCGGGCGGCGCGGACGCGAACAGCAGCGGCGGCGGCGGGCGCGGCCTCCTGGG
CGCGGGGCGCGCGGTGCCTGAGGGCGGGCGCGCGGGCGCTGGGCAACTGCCGGCCGCGCCGCCTGCGCAGGCGCTGGTTCAGGACTCACA
CGCCGCGCTGAGGCCCGCGGGCCCGTCATGGAGGCGCCCACCGTGGAGACGCCCCCCGACCCCTCGCCCCCTTCGGCCCCGGCCCCTGCC
CTGGTTCCGTTGCGCGCCCCGGATGTGGCGCGGCTGCGCGAGGAGCAGGAAAAGGTGGTCACTAACTGCCAAGAGAGAATCCAGCATTGG
AAGAAGGTAGATAATGACTATAATGCCCTTCGAGAAAGACTCAGCACCTTGCCTGATAAATTGTCTTATAATATAATGGTACCATTTGGC
CCTTTTGCCTTCATGCCAGGAAAACTTGTCCATACTAATGAAGTCACTGTTTTACTGGGGGACAACTGGTTTGCAAAGTGCTCAGCAAAG
CAGGCTGTAGGTTTAGTTGAGCACCGGAAAGAACGGGAAAATAAGCTGGTAGGGGACCTTCTGGTCTTAGGAGGAGCCACACTCTATGGT
ATTTCTAACGTCTGGGAAGAATACATCATCCGAACTCTGAGCCGAGTGGAATTCCTGGGAATGATTGGTCTCTTTGGAGCATTTTTCAGT
GGAATTCAATTAGCTATAATGGAGCATAAGGAACTGTTGAAGGTGCCCTGGGACTGGCAAATAGGACTGCTCTACGTTGGCTTTAGTGCC
TGCATGTTTGGTCTCTACAGCTTTATGCCAGTCGTCATAAAGAAAACCAGTGCCACTTCAGTCAACCTCTCCTTGCTCACAGCAGACTTG
TACAGCCTGTTCTGTGGATTGTTTCTCTTCCACTACAAGTTTTCAGGACTTTATCTCCTGTCTTTCTTCACCATCCTCATTGGGCTGGTG
CTCTACTCCTCCACCTCCACCTACATAGCCCAGGACCCCCGAGTGTATAAGCAGTTCCGCAATCCTTCAGGACCTGTTGTGGACTTACCG
ACCACAGCTCAGGTGGAACCCTCAGTCACCTACACCAGCCTGGGCCAGGAGACCGAAGAGGAGCCTCATGTTCGTGTGGCCTAGGGTGAG
GCCCGCCCTGCCAACTGAGGCCAACTCATTGGCCATGTTTTTGCCCATCATCTCTGTATTGTACATAGAGAAAGGTATTTACTAGGTGCA
GTTTACACAGGTGGACTGCAAGGTAGCAAATCCTCCAAAAGCTTGTGAAAGGAACAAGCTCAACATCACTGGAGACACAGGCTCTAATCC
ACCTGACTTGGAAGGATGCCTAGCTAACGTGTATCCTGATCACAACTCCCCTGCATTCATTACTGTGAAAATTTTTGAATCAAAAGCAAG
TATTATTGTTATTATGATTTGTATTATTATTATTGCTGTTACTGTTATTACACCAACTTTCAGGAGGATGTTTTGTACTCCTGATGGAAA
CTATTGCCAGACCCACATGTAGTCAACATAAACCCCACTTTTCTATGGCAATTCACTTTTTAAGAGTCATACTTTATTTTTTTGCACAGA
CTATATGAGTGATGCATGCCACAGGAGCTCCACCCCTGAGAAGTTTCCTTTTCCTAGGGACCTGGTGGTTAATGGTTTCCTCTGTTACCT
GTTGGATTGCCTGCTCAATAAGTATTTTGTGCTGTGACCTTTGTGGGGAGGGGCAACTGACCATATACTTCTCTATTCTAGGAATAGATA
TAAAAGAAACATTTTAGCCTTTTTATATTTCGATCTCTGATTACTCCAGGCCATTGCCTTTCTGTTGTGCCACGTGATTCTGCTAATCAA
GTCCCTGTAATAACAGGATAAGGACTGTTCCATTACTGTGGCTTTTGGGAGCCCCCAGAAATAATATCATTTGTGTTTAGGACAATATAT
AATTATAAAATCTTTCTGCTCCTCCCTGTAGCCTCTCTTCAAAAACTATCTTTTATTTTTTTTCCAGATTTCCTTAGTGATAATATGGAA
ATTAATCAAGGCACTGGAAAAAGCCATGGTCCTCTGCCCTTTTAATTCTGTGACACCTTTTTAAAAATACACCAGCATGGAAATTACCTT
TATTGTGGAAAATCATTGGTTGTGCCACCTCCTAACAAAGTCAAGGTGCTGATGTGGAGCAGTCTTTGAAAATGGCTTAATTGATTTGGC
CACTTTGCAGTGGTAACAATGTCATCATTGAAAAAGTCTGGCATTTTGGTCATATTTGGCATCCATTCAATAACAGATATATTGACACGA
CATTCTTTTTTTTTTTTTTTTTTTTTTTTGAGACGGAGTCTCACTCTGTCGCCCAGGCTGGAGTGCGGTGGCACGATCTCAGCTCACTGC
AACCTCCGCCTCCGGGATTCACACCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCACCTGCCACGACGCCCAGCTAATT
TTTTGTATTTTTAGTAGAGATGGGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCGCCCACCTTGGCCTCCC
GAAGTGCTGGGATTACAGGCGTGAGCCACTGCGCCCGGCCGACACGACATTCTTATGGACCCAGAGAATACTGCAGGATCCTGATAAGAC
CTTGAGTGATATGTCACTAGTCTAATCTGTTGCCCTTAAAATAGCCCTTTTTTCAAACACAGGAAATTAAGAAACACCACAGACCTCTAT
TATTTAGAATAGATTCTATGTGTCAGTATGTGATGTACTCTTTTAGTTTGACTGACTTCAATACCATTCAAAAAGATCCTCAATGGAGTT
ACAGGGTTTATAGGGGAAAAATACATGTTTATGAGACATTGGGCAATTCAAATCAACATGTGTTACATAAGCAAGCAAAGCAAAACACCA
GTGGGGTCTCTGGAAAGTAAAAGGACAGACTACAGTAGAAGGACTGATCCCAGAGTGCCTGTACAAGGCCTAAATCTGGCAGGCAAAAGC
ATCCCACACTGTCTGTCAGCACCCACATGGCCTTTTTGCCTGCCTTCTATAACGGGTAAGTGGACCTACCCTTGGAGATAGAGAAGAAAA
ATTATCTTCTCTGATATTCGGATGTAATGGTCATCTCAGTTCAGCCCCCTAGGAAACATGTTTTATTTTCCATGGGGAAAATATCAGCGT
TAAAGCTCTATCAAATCAAAACAACTTTGCCAACATCTTCTCTCTGCTACCTTTTAAACCAATTAAATACCTTTCTCTGAATATTTTGTC
CATTCAGATCCGAAGACCTTTAAAGACTGTGGTTTTATTTTTGTGTTTACATTCCTTTGGTTTGAATAATTTGCTTGATTTATTGCATTT
TTAGTATTTATTTTAAGCCAGATGTTTTCATCTTTGATTCATTTTTATGACATTAATTTGTAGACACTTAGTAAAGTCTTATGAGAAGCA
AGTGGATGAAATTATCTCCAAGTCCACTCAGTAGACTGGAGTTTTTTAAAAATATAAATTTCCAAAAAGTTTGCAATCAACAGATGGCTA
AAGGTTGCCATCTGAATTATTTTATAGGATATTTTAATTGACTCCATTGTATGGAAACCAAGTGTGAATGTTAAGATGAATTTGCCGTAT
ACCCTTTATCATTCGGTGTCCTTGTACTCAGACTTTCATGTCCCTGGGTGACCTCAATGTGTTGGTTTGTCTCCATTTAGAAAGGTTGAT
AATATATTGAATTGTTCAAGATCAGGAGTTCCAGACTGACCCTCCAGGAAAAAAAAAATCGCAAAGAACAAATTCTTTTTCTGTGTAAAA
AACACTGATCCTTTGGGAATGGGGCGGGAAATGGGAGTAGGACAACATTAACTTTAGCTGTTTTAGTTTCTGAGATTTCATAACCTCAGT
AGACACCAGCAAAATTTTCAGTTTCTAACTCCACCACCAATCTCTCCTCAATGAATAAGACTTTAGCAATTTATATAGAATTTGATCAGG
TAAGAGCGAACCACAATTCTCCTGAACCCTGCTAGAGATTAAGTGGTGGTTCTCACTTCCTCAATGAAAACTTGCACTGGGGACAGCGCT
TGCCTTGGTCAGACCTTCCCACATCTACATACTCTCAAATACATGACCAGGTGATCAAGCAATGGAAAAATTTGCACCACCGTGTCCCAT
GAAATTGTTTCAATGTTTAGTTTAGATATTGCTAACTTGTGCTATTAACCTTTTGACAAGCGTGTAGTATTGTTTGTTTTGGGTTTCTTT
TTGATTTATAACTATTTAGTAGTCCCCAGCTAGCTACCAGTACAGATTTTACCCCATGGGTAGGATTCTATTGTTAAGCCACATAACAAA
GCACACTAATTCTGACAACACTGCAAATGGAAAATACGAACCAAAAAAAAGTTACACCGATAAGTTCAACAAACTGTCCATTTTTGATAT

>97086_97086_3_URI1-SLC35F1_URI1_chr19_30477324_ENST00000392271_SLC35F1_chr6_118596622_ENST00000360388_length(amino acids)=318AA_BP=123
MEAPTVETPPDPSPPSAPAPALVPLRAPDVARLREEQEKVVTNCQERIQHWKKVDNDYNALRERLSTLPDKLSYNIMVPFGPFAFMPGKL
VHTNEVTVLLGDNWFAKCSAKQAVGLVEHRKERENKLVGDLLVLGGATLYGISNVWEEYIIRTLSRVEFLGMIGLFGAFFSGIQLAIMEH
KELLKVPWDWQIGLLYVGFSACMFGLYSFMPVVIKKTSATSVNLSLLTADLYSLFCGLFLFHYKFSGLYLLSFFTILIGLVLYSSTSTYI

--------------------------------------------------------------
>97086_97086_4_URI1-SLC35F1_URI1_chr19_30477324_ENST00000542441_SLC35F1_chr6_118596622_ENST00000360388_length(transcript)=4678nt_BP=664nt
GCGGCCGCCACGCGACGCCTGGCTGGGCCCGCACCGGAGAGGCGTCTCGGTACCTGGCAGGCGGCCTGCTACTCGGAGCCCGCTGCGGGG
CGGCGGCGGCGGGGACATGCACGTGTGAGATGCGGCAGCGGGCGGCGCGGACGCGAACAGCAGCGGCGGCGGCGGGCGCGGCCTCCTGGG
CGCGGGGCGCGCGGTGCCTGAGGGCGGGCGCGCGGGCGCTGGGCAACTGCCGGCCGCGCCGCCTGCGCAGGCGCTGGTTCAGGACTCACA
CGCCGCGCTGAGGCCCGCGGGCCCGTCATGGAGGCGCCCACCGTGGAGACGCCCCCCGACCCCTCGCCCCCTTCGGCCCCGGCCCCTGCC
CTGGTTCCGTTGCGCGCCCCGGATGTGGCGCGGCTGCGCGAGGAGCAGGAAAAGGTGGTCACTAACTGCCAAGAGAGAATCCAGCATTGG
AAGAAGGTAGATAATGACTATAATGCCCTTCGAGAAAGACTCAGCACCTTGCCTGATAAATTGTCTTATAATATAATGGTACCATTTGGC
CCTTTTGCCTTCATGCCAGGAAAACTTGTCCATACTAATGAAGTCACTGTTTTACTGGGGGACAACTGGTTTGCAAAGTGCTCAGCAAAG
CAGGCTGTAGGTTTAGTTGAGCACCGGAAAGAACGGGAAAATAAGCTGGTAGGGGACCTTCTGGTCTTAGGAGGAGCCACACTCTATGGT
ATTTCTAACGTCTGGGAAGAATACATCATCCGAACTCTGAGCCGAGTGGAATTCCTGGGAATGATTGGTCTCTTTGGAGCATTTTTCAGT
GGAATTCAATTAGCTATAATGGAGCATAAGGAACTGTTGAAGGTGCCCTGGGACTGGCAAATAGGACTGCTCTACGTTGGCTTTAGTGCC
TGCATGTTTGGTCTCTACAGCTTTATGCCAGTCGTCATAAAGAAAACCAGTGCCACTTCAGTCAACCTCTCCTTGCTCACAGCAGACTTG
TACAGCCTGTTCTGTGGATTGTTTCTCTTCCACTACAAGTTTTCAGGACTTTATCTCCTGTCTTTCTTCACCATCCTCATTGGGCTGGTG
CTCTACTCCTCCACCTCCACCTACATAGCCCAGGACCCCCGAGTGTATAAGCAGTTCCGCAATCCTTCAGGACCTGTTGTGGACTTACCG
ACCACAGCTCAGGTGGAACCCTCAGTCACCTACACCAGCCTGGGCCAGGAGACCGAAGAGGAGCCTCATGTTCGTGTGGCCTAGGGTGAG
GCCCGCCCTGCCAACTGAGGCCAACTCATTGGCCATGTTTTTGCCCATCATCTCTGTATTGTACATAGAGAAAGGTATTTACTAGGTGCA
GTTTACACAGGTGGACTGCAAGGTAGCAAATCCTCCAAAAGCTTGTGAAAGGAACAAGCTCAACATCACTGGAGACACAGGCTCTAATCC
ACCTGACTTGGAAGGATGCCTAGCTAACGTGTATCCTGATCACAACTCCCCTGCATTCATTACTGTGAAAATTTTTGAATCAAAAGCAAG
TATTATTGTTATTATGATTTGTATTATTATTATTGCTGTTACTGTTATTACACCAACTTTCAGGAGGATGTTTTGTACTCCTGATGGAAA
CTATTGCCAGACCCACATGTAGTCAACATAAACCCCACTTTTCTATGGCAATTCACTTTTTAAGAGTCATACTTTATTTTTTTGCACAGA
CTATATGAGTGATGCATGCCACAGGAGCTCCACCCCTGAGAAGTTTCCTTTTCCTAGGGACCTGGTGGTTAATGGTTTCCTCTGTTACCT
GTTGGATTGCCTGCTCAATAAGTATTTTGTGCTGTGACCTTTGTGGGGAGGGGCAACTGACCATATACTTCTCTATTCTAGGAATAGATA
TAAAAGAAACATTTTAGCCTTTTTATATTTCGATCTCTGATTACTCCAGGCCATTGCCTTTCTGTTGTGCCACGTGATTCTGCTAATCAA
GTCCCTGTAATAACAGGATAAGGACTGTTCCATTACTGTGGCTTTTGGGAGCCCCCAGAAATAATATCATTTGTGTTTAGGACAATATAT
AATTATAAAATCTTTCTGCTCCTCCCTGTAGCCTCTCTTCAAAAACTATCTTTTATTTTTTTTCCAGATTTCCTTAGTGATAATATGGAA
ATTAATCAAGGCACTGGAAAAAGCCATGGTCCTCTGCCCTTTTAATTCTGTGACACCTTTTTAAAAATACACCAGCATGGAAATTACCTT
TATTGTGGAAAATCATTGGTTGTGCCACCTCCTAACAAAGTCAAGGTGCTGATGTGGAGCAGTCTTTGAAAATGGCTTAATTGATTTGGC
CACTTTGCAGTGGTAACAATGTCATCATTGAAAAAGTCTGGCATTTTGGTCATATTTGGCATCCATTCAATAACAGATATATTGACACGA
CATTCTTTTTTTTTTTTTTTTTTTTTTTTGAGACGGAGTCTCACTCTGTCGCCCAGGCTGGAGTGCGGTGGCACGATCTCAGCTCACTGC
AACCTCCGCCTCCGGGATTCACACCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCACCTGCCACGACGCCCAGCTAATT
TTTTGTATTTTTAGTAGAGATGGGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCGCCCACCTTGGCCTCCC
GAAGTGCTGGGATTACAGGCGTGAGCCACTGCGCCCGGCCGACACGACATTCTTATGGACCCAGAGAATACTGCAGGATCCTGATAAGAC
CTTGAGTGATATGTCACTAGTCTAATCTGTTGCCCTTAAAATAGCCCTTTTTTCAAACACAGGAAATTAAGAAACACCACAGACCTCTAT
TATTTAGAATAGATTCTATGTGTCAGTATGTGATGTACTCTTTTAGTTTGACTGACTTCAATACCATTCAAAAAGATCCTCAATGGAGTT
ACAGGGTTTATAGGGGAAAAATACATGTTTATGAGACATTGGGCAATTCAAATCAACATGTGTTACATAAGCAAGCAAAGCAAAACACCA
GTGGGGTCTCTGGAAAGTAAAAGGACAGACTACAGTAGAAGGACTGATCCCAGAGTGCCTGTACAAGGCCTAAATCTGGCAGGCAAAAGC
ATCCCACACTGTCTGTCAGCACCCACATGGCCTTTTTGCCTGCCTTCTATAACGGGTAAGTGGACCTACCCTTGGAGATAGAGAAGAAAA
ATTATCTTCTCTGATATTCGGATGTAATGGTCATCTCAGTTCAGCCCCCTAGGAAACATGTTTTATTTTCCATGGGGAAAATATCAGCGT
TAAAGCTCTATCAAATCAAAACAACTTTGCCAACATCTTCTCTCTGCTACCTTTTAAACCAATTAAATACCTTTCTCTGAATATTTTGTC
CATTCAGATCCGAAGACCTTTAAAGACTGTGGTTTTATTTTTGTGTTTACATTCCTTTGGTTTGAATAATTTGCTTGATTTATTGCATTT
TTAGTATTTATTTTAAGCCAGATGTTTTCATCTTTGATTCATTTTTATGACATTAATTTGTAGACACTTAGTAAAGTCTTATGAGAAGCA
AGTGGATGAAATTATCTCCAAGTCCACTCAGTAGACTGGAGTTTTTTAAAAATATAAATTTCCAAAAAGTTTGCAATCAACAGATGGCTA
AAGGTTGCCATCTGAATTATTTTATAGGATATTTTAATTGACTCCATTGTATGGAAACCAAGTGTGAATGTTAAGATGAATTTGCCGTAT
ACCCTTTATCATTCGGTGTCCTTGTACTCAGACTTTCATGTCCCTGGGTGACCTCAATGTGTTGGTTTGTCTCCATTTAGAAAGGTTGAT
AATATATTGAATTGTTCAAGATCAGGAGTTCCAGACTGACCCTCCAGGAAAAAAAAAATCGCAAAGAACAAATTCTTTTTCTGTGTAAAA
AACACTGATCCTTTGGGAATGGGGCGGGAAATGGGAGTAGGACAACATTAACTTTAGCTGTTTTAGTTTCTGAGATTTCATAACCTCAGT
AGACACCAGCAAAATTTTCAGTTTCTAACTCCACCACCAATCTCTCCTCAATGAATAAGACTTTAGCAATTTATATAGAATTTGATCAGG
TAAGAGCGAACCACAATTCTCCTGAACCCTGCTAGAGATTAAGTGGTGGTTCTCACTTCCTCAATGAAAACTTGCACTGGGGACAGCGCT
TGCCTTGGTCAGACCTTCCCACATCTACATACTCTCAAATACATGACCAGGTGATCAAGCAATGGAAAAATTTGCACCACCGTGTCCCAT
GAAATTGTTTCAATGTTTAGTTTAGATATTGCTAACTTGTGCTATTAACCTTTTGACAAGCGTGTAGTATTGTTTGTTTTGGGTTTCTTT
TTGATTTATAACTATTTAGTAGTCCCCAGCTAGCTACCAGTACAGATTTTACCCCATGGGTAGGATTCTATTGTTAAGCCACATAACAAA
GCACACTAATTCTGACAACACTGCAAATGGAAAATACGAACCAAAAAAAAGTTACACCGATAAGTTCAACAAACTGTCCATTTTTGATAT

>97086_97086_4_URI1-SLC35F1_URI1_chr19_30477324_ENST00000542441_SLC35F1_chr6_118596622_ENST00000360388_length(amino acids)=318AA_BP=123
MEAPTVETPPDPSPPSAPAPALVPLRAPDVARLREEQEKVVTNCQERIQHWKKVDNDYNALRERLSTLPDKLSYNIMVPFGPFAFMPGKL
VHTNEVTVLLGDNWFAKCSAKQAVGLVEHRKERENKLVGDLLVLGGATLYGISNVWEEYIIRTLSRVEFLGMIGLFGAFFSGIQLAIMEH
KELLKVPWDWQIGLLYVGFSACMFGLYSFMPVVIKKTSATSVNLSLLTADLYSLFCGLFLFHYKFSGLYLLSFFTILIGLVLYSSTSTYI

--------------------------------------------------------------

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Fusion Gene PPI Analysis for URI1-SLC35F1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for URI1-SLC35F1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for URI1-SLC35F1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource