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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:USF2-HPN (FusionGDB2 ID:97121)

Fusion Gene Summary for USF2-HPN

check button Fusion gene summary
Fusion gene informationFusion gene name: USF2-HPN
Fusion gene ID: 97121
HgeneTgene
Gene symbol

USF2

HPN

Gene ID

7392

3249

Gene nameupstream transcription factor 2, c-fos interactinghepsin
SynonymsFIP|bHLHb12TMPRSS1
Cytomap

19q13.12

19q13.11

Type of geneprotein-codingprotein-coding
Descriptionupstream stimulatory factor 2c-fos interacting proteinclass B basic helix-loop-helix protein 12major late transcription factor 2serine protease hepsintesticular tissue protein Li 85transmembrane protease serine 1
Modification date2020031320200322
UniProtAcc.

P05981

Ensembl transtripts involved in fusion geneENST00000600341, ENST00000222305, 
ENST00000343550, ENST00000379134, 
ENST00000594064, ENST00000595068, 
ENST00000262626, ENST00000392226, 
ENST00000597419, ENST00000600675, 
Fusion gene scores* DoF score5 X 4 X 5=1003 X 5 X 3=45
# samples 74
** MAII scorelog2(7/100*10)=-0.514573172829758
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/45*10)=-0.169925001442312
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: USF2 [Title/Abstract] AND HPN [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointUSF2(35762044)-HPN(35540193), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneHPN

GO:0006508

proteolysis

16908524|19843851|19911255|24227843

TgeneHPN

GO:0010719

negative regulation of epithelial to mesenchymal transition

19843851

TgeneHPN

GO:0010756

positive regulation of plasminogen activation

16908524

TgeneHPN

GO:0034769

basement membrane disassembly

16908524

TgeneHPN

GO:0043066

negative regulation of apoptotic process

15614436

TgeneHPN

GO:0043923

positive regulation by host of viral transcription

15614436

TgeneHPN

GO:0050680

negative regulation of epithelial cell proliferation

19843851

TgeneHPN

GO:2000347

positive regulation of hepatocyte proliferation

15614436


check buttonFusion gene breakpoints across USF2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across HPN (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-BR-6454USF2chr19

35762044

+HPNchr19

35540193

+


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Fusion Gene ORF analysis for USF2-HPN

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000600341ENST00000262626USF2chr19

35762044

+HPNchr19

35540193

+
3UTR-3CDSENST00000600341ENST00000392226USF2chr19

35762044

+HPNchr19

35540193

+
3UTR-intronENST00000600341ENST00000597419USF2chr19

35762044

+HPNchr19

35540193

+
3UTR-intronENST00000600341ENST00000600675USF2chr19

35762044

+HPNchr19

35540193

+
5CDS-intronENST00000222305ENST00000597419USF2chr19

35762044

+HPNchr19

35540193

+
5CDS-intronENST00000222305ENST00000600675USF2chr19

35762044

+HPNchr19

35540193

+
5CDS-intronENST00000343550ENST00000597419USF2chr19

35762044

+HPNchr19

35540193

+
5CDS-intronENST00000343550ENST00000600675USF2chr19

35762044

+HPNchr19

35540193

+
5CDS-intronENST00000379134ENST00000597419USF2chr19

35762044

+HPNchr19

35540193

+
5CDS-intronENST00000379134ENST00000600675USF2chr19

35762044

+HPNchr19

35540193

+
5CDS-intronENST00000594064ENST00000597419USF2chr19

35762044

+HPNchr19

35540193

+
5CDS-intronENST00000594064ENST00000600675USF2chr19

35762044

+HPNchr19

35540193

+
5CDS-intronENST00000595068ENST00000597419USF2chr19

35762044

+HPNchr19

35540193

+
5CDS-intronENST00000595068ENST00000600675USF2chr19

35762044

+HPNchr19

35540193

+
In-frameENST00000222305ENST00000262626USF2chr19

35762044

+HPNchr19

35540193

+
In-frameENST00000222305ENST00000392226USF2chr19

35762044

+HPNchr19

35540193

+
In-frameENST00000343550ENST00000262626USF2chr19

35762044

+HPNchr19

35540193

+
In-frameENST00000343550ENST00000392226USF2chr19

35762044

+HPNchr19

35540193

+
In-frameENST00000379134ENST00000262626USF2chr19

35762044

+HPNchr19

35540193

+
In-frameENST00000379134ENST00000392226USF2chr19

35762044

+HPNchr19

35540193

+
In-frameENST00000594064ENST00000262626USF2chr19

35762044

+HPNchr19

35540193

+
In-frameENST00000594064ENST00000392226USF2chr19

35762044

+HPNchr19

35540193

+
In-frameENST00000595068ENST00000262626USF2chr19

35762044

+HPNchr19

35540193

+
In-frameENST00000595068ENST00000392226USF2chr19

35762044

+HPNchr19

35540193

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000343550USF2chr1935762044+ENST00000392226HPNchr1935540193+21726501241887587
ENST00000343550USF2chr1935762044+ENST00000262626HPNchr1935540193+21726501241887587
ENST00000222305USF2chr1935762044+ENST00000392226HPNchr1935540193+2286764372001654
ENST00000222305USF2chr1935762044+ENST00000262626HPNchr1935540193+2286764372001654
ENST00000595068USF2chr1935762044+ENST00000392226HPNchr1935540193+2286764372001654
ENST00000595068USF2chr1935762044+ENST00000262626HPNchr1935540193+2286764372001654
ENST00000379134USF2chr1935762044+ENST00000392226HPNchr1935540193+185633401571523
ENST00000379134USF2chr1935762044+ENST00000262626HPNchr1935540193+185633401571523
ENST00000594064USF2chr1935762044+ENST00000392226HPNchr1935540193+224372101958652
ENST00000594064USF2chr1935762044+ENST00000262626HPNchr1935540193+224372101958652

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000343550ENST00000392226USF2chr1935762044+HPNchr1935540193+0.0124353390.9875646
ENST00000343550ENST00000262626USF2chr1935762044+HPNchr1935540193+0.0124353390.9875646
ENST00000222305ENST00000392226USF2chr1935762044+HPNchr1935540193+0.0049562730.99504375
ENST00000222305ENST00000262626USF2chr1935762044+HPNchr1935540193+0.0049562730.99504375
ENST00000595068ENST00000392226USF2chr1935762044+HPNchr1935540193+0.0049562730.99504375
ENST00000595068ENST00000262626USF2chr1935762044+HPNchr1935540193+0.0049562730.99504375
ENST00000379134ENST00000392226USF2chr1935762044+HPNchr1935540193+0.0303534880.9696465
ENST00000379134ENST00000262626USF2chr1935762044+HPNchr1935540193+0.0303534880.9696465
ENST00000594064ENST00000392226USF2chr1935762044+HPNchr1935540193+0.0055254690.9944745
ENST00000594064ENST00000262626USF2chr1935762044+HPNchr1935540193+0.0055254690.9944745

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Fusion Genomic Features for USF2-HPN


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
USF2chr1935762044+HPNchr1935540193+4.14E-050.9999585
USF2chr1935762044+HPNchr1935540193+4.14E-050.9999585

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for USF2-HPN


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:35762044/chr19:35540193)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.HPN

P05981

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Serine protease that cleaves extracellular substrates, and contributes to the proteolytic processing of growth factors, such as HGF and MST1/HGFL (PubMed:21875933, PubMed:15839837). Plays a role in cell growth and maintenance of cell morphology (PubMed:8346233, PubMed:21875933). Plays a role in the proteolytic processing of ACE2 (PubMed:24227843). Mediates the proteolytic cleavage of urinary UMOD that is required for UMOD polymerization (PubMed:26673890). {ECO:0000269|PubMed:15839837, ECO:0000269|PubMed:21875933, ECO:0000269|PubMed:24227843, ECO:0000269|PubMed:26673890, ECO:0000269|PubMed:8346233}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneUSF2chr19:35762044chr19:35540193ENST00000222305+71011_20242347.0Compositional biasNote=Poly-Ala
HgeneUSF2chr19:35762044chr19:35540193ENST00000343550+6911_20175280.0Compositional biasNote=Poly-Ala
HgeneUSF2chr19:35762044chr19:35540193ENST00000379134+5811_20111216.0Compositional biasNote=Poly-Ala
HgeneUSF2chr19:35762044chr19:35540193ENST00000595068+71011_20242339.0Compositional biasNote=Poly-Ala
TgeneHPNchr19:35762044chr19:35540193ENST00000262626113163_4055418.0DomainPeptidase S1
TgeneHPNchr19:35762044chr19:35540193ENST0000026262611354_1515418.0DomainNote=SRCR
TgeneHPNchr19:35762044chr19:35540193ENST00000392226214163_4055418.0DomainPeptidase S1
TgeneHPNchr19:35762044chr19:35540193ENST0000039222621454_1515418.0DomainNote=SRCR
TgeneHPNchr19:35762044chr19:35540193ENST0000026262611345_4175418.0Topological domainExtracellular
TgeneHPNchr19:35762044chr19:35540193ENST0000039222621445_4175418.0Topological domainExtracellular
TgeneHPNchr19:35762044chr19:35540193ENST0000026262611324_445418.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneHPNchr19:35762044chr19:35540193ENST0000039222621424_445418.0TransmembraneHelical%3B Signal-anchor for type II membrane protein

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneUSF2chr19:35762044chr19:35540193ENST00000222305+710245_248242347.0Compositional biasNote=Poly-Arg
HgeneUSF2chr19:35762044chr19:35540193ENST00000343550+69245_248175280.0Compositional biasNote=Poly-Arg
HgeneUSF2chr19:35762044chr19:35540193ENST00000379134+58245_248111216.0Compositional biasNote=Poly-Arg
HgeneUSF2chr19:35762044chr19:35540193ENST00000595068+710245_248242339.0Compositional biasNote=Poly-Arg
HgeneUSF2chr19:35762044chr19:35540193ENST00000222305+710235_290242347.0DomainbHLH
HgeneUSF2chr19:35762044chr19:35540193ENST00000343550+69235_290175280.0DomainbHLH
HgeneUSF2chr19:35762044chr19:35540193ENST00000379134+58235_290111216.0DomainbHLH
HgeneUSF2chr19:35762044chr19:35540193ENST00000595068+710235_290242339.0DomainbHLH
HgeneUSF2chr19:35762044chr19:35540193ENST00000222305+710307_328242347.0RegionNote=Leucine-zipper
HgeneUSF2chr19:35762044chr19:35540193ENST00000343550+69307_328175280.0RegionNote=Leucine-zipper
HgeneUSF2chr19:35762044chr19:35540193ENST00000379134+58307_328111216.0RegionNote=Leucine-zipper
HgeneUSF2chr19:35762044chr19:35540193ENST00000595068+710307_328242339.0RegionNote=Leucine-zipper
TgeneHPNchr19:35762044chr19:35540193ENST000002626261131_235418.0Topological domainCytoplasmic
TgeneHPNchr19:35762044chr19:35540193ENST000003922262141_235418.0Topological domainCytoplasmic


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Fusion Gene Sequence for USF2-HPN


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>97121_97121_1_USF2-HPN_USF2_chr19_35762044_ENST00000222305_HPN_chr19_35540193_ENST00000262626_length(transcript)=2286nt_BP=764nt
CCCCGGGCCCCGCGCCCCCCCCGCCCCCGCCCCCCCCATGGACATGCTGGACCCGGGTCTGGATCCCGCTGCCTCGGCCACCGCTGCTGC
CGCCGCCAGCCACGACAAGGGACCCGAGGCGGAGGAGGGCGTCGAGCTGCAGGAAGGCGGGGACGGCCCAGGAGCGGAGGAGCAGACAGC
GGTGGCCATCACCAGCGTCCAGCAGGCGGCGTTCGGCGACCACAACATCCAGTACCAGTTCCGCACAGAGACAAATGGAGGACAGGTGAC
ATACCGCGTAGTCCAGGTGACTGATGGTCAGCTGGACGGCCAGGGCGACACAGCTGGCGCCGTCAGCGTCGTGTCCACCGCTGCCTTCGC
GGGGGGGCAGCAGGCTGTGACCCAGGTGGGTGTGGACGGGGCAGCCCAGCGCCCGGGCCCCGCCGCTGCCTCTGTGCCCCCAGGTCCTGC
AGCGCCCTTCCCGCTGGCTGTGATCCAAAATCCCTTCAGCAATGGTGGCAGTCCGGCGGCCGAGGCTGTCAGCGGGGAGGCACGATTTGC
CTATTTCCCAGCGTCCAGTGTGGGAGATACTACGGCTGTGTCCGTACAGACCACAGACCAGAGCTTGCAGGCTGGAGGCCAGTTCTACGT
CATGATGACGCCCCAGGATGTGCTTCAGACAGGAACACAGAGGACGATCGCCCCCCGGACACACCCTTACTCTCCAAAAATTGATGGAAC
CAGAACACCCCGAGATGAGAGGAGAAGAGCCCAGCACAACGAAGGTGGCCGGACTGTGCCATGCTGCTCCAGACCCAAGGTGGCAGCTCT
CACTGCGGGGACCCTGCTACTTCTGACAGCCATCGGGGCGGCATCCTGGGCCATTGTGGCTGTTCTCCTCAGGAGTGACCAGGAGCCGCT
GTACCCAGTGCAGGTCAGCTCTGCGGACGCTCGGCTCATGGTCTTTGACAAGACGGAAGGGACGTGGCGGCTGCTGTGCTCCTCGCGCTC
CAACGCCAGGGTAGCCGGACTCAGCTGCGAGGAGATGGGCTTCCTCAGGGCACTGACCCACTCCGAGCTGGACGTGCGAACGGCGGGCGC
CAATGGCACGTCGGGCTTCTTCTGTGTGGACGAGGGGAGGCTGCCCCACACCCAGAGGCTGCTGGAGGTCATCTCCGTGTGTGATTGCCC
CAGAGGCCGTTTCTTGGCCGCCATCTGCCAAGACTGTGGCCGCAGGAAGCTGCCCGTGGACCGCATCGTGGGAGGCCGGGACACCAGCTT
GGGCCGGTGGCCGTGGCAAGTCAGCCTTCGCTATGATGGAGCACACCTCTGTGGGGGATCCCTGCTCTCCGGGGACTGGGTGCTGACAGC
CGCCCACTGCTTCCCGGAGCGGAACCGGGTCCTGTCCCGATGGCGAGTGTTTGCCGGTGCCGTGGCCCAGGCCTCTCCCCACGGTCTGCA
GCTGGGGGTGCAGGCTGTGGTCTACCACGGGGGCTATCTTCCCTTTCGGGACCCCAACAGCGAGGAGAACAGCAACGATATTGCCCTGGT
CCACCTCTCCAGTCCCCTGCCCCTCACAGAATACATCCAGCCTGTGTGCCTCCCAGCTGCCGGCCAGGCCCTGGTGGATGGCAAGATCTG
TACCGTGACGGGCTGGGGCAACACGCAGTACTATGGCCAACAGGCCGGGGTACTCCAGGAGGCTCGAGTCCCCATAATCAGCAATGATGT
CTGCAATGGCGCTGACTTCTATGGAAACCAGATCAAGCCCAAGATGTTCTGTGCTGGCTACCCCGAGGGTGGCATTGATGCCTGCCAGGG
CGACAGCGGTGGTCCCTTTGTGTGTGAGGACAGCATCTCTCGGACGCCACGTTGGCGGCTGTGTGGCATTGTGAGTTGGGGCACTGGCTG
TGCCCTGGCCCAGAAGCCAGGCGTCTACACCAAAGTCAGTGACTTCCGGGAGTGGATCTTCCAGGCCATAAAGACTCACTCCGAAGCCAG
CGGCATGGTGACCCAGCTCTGACCGGTGGCTTCTCGCTGCGCAGCCTCCAGGGCCCGAGGTGATCCCGGTGGTGGGATCCACGCTGGGCC
TAGGATGGGACGTTTTTCTTCTTGGGCCCGGTCCACAGGTCCAAGGACACCCTCCCTCCAGGGTCCTCTCTTCCACAGTGGCGGGCCCAC
TCAGCCCCGAGACCACCCAACCTCACCCTCCTGACCCCCATGTAAATATTGTTCTGCTGTCTGGGACTCCTGTCTAGGTGCCCCTGATGA

>97121_97121_1_USF2-HPN_USF2_chr19_35762044_ENST00000222305_HPN_chr19_35540193_ENST00000262626_length(amino acids)=654AA_BP=242
MDMLDPGLDPAASATAAAAASHDKGPEAEEGVELQEGGDGPGAEEQTAVAITSVQQAAFGDHNIQYQFRTETNGGQVTYRVVQVTDGQLD
GQGDTAGAVSVVSTAAFAGGQQAVTQVGVDGAAQRPGPAAASVPPGPAAPFPLAVIQNPFSNGGSPAAEAVSGEARFAYFPASSVGDTTA
VSVQTTDQSLQAGGQFYVMMTPQDVLQTGTQRTIAPRTHPYSPKIDGTRTPRDERRRAQHNEGGRTVPCCSRPKVAALTAGTLLLLTAIG
AASWAIVAVLLRSDQEPLYPVQVSSADARLMVFDKTEGTWRLLCSSRSNARVAGLSCEEMGFLRALTHSELDVRTAGANGTSGFFCVDEG
RLPHTQRLLEVISVCDCPRGRFLAAICQDCGRRKLPVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLS
RWRVFAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYG
QQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKV

--------------------------------------------------------------
>97121_97121_2_USF2-HPN_USF2_chr19_35762044_ENST00000222305_HPN_chr19_35540193_ENST00000392226_length(transcript)=2286nt_BP=764nt
CCCCGGGCCCCGCGCCCCCCCCGCCCCCGCCCCCCCCATGGACATGCTGGACCCGGGTCTGGATCCCGCTGCCTCGGCCACCGCTGCTGC
CGCCGCCAGCCACGACAAGGGACCCGAGGCGGAGGAGGGCGTCGAGCTGCAGGAAGGCGGGGACGGCCCAGGAGCGGAGGAGCAGACAGC
GGTGGCCATCACCAGCGTCCAGCAGGCGGCGTTCGGCGACCACAACATCCAGTACCAGTTCCGCACAGAGACAAATGGAGGACAGGTGAC
ATACCGCGTAGTCCAGGTGACTGATGGTCAGCTGGACGGCCAGGGCGACACAGCTGGCGCCGTCAGCGTCGTGTCCACCGCTGCCTTCGC
GGGGGGGCAGCAGGCTGTGACCCAGGTGGGTGTGGACGGGGCAGCCCAGCGCCCGGGCCCCGCCGCTGCCTCTGTGCCCCCAGGTCCTGC
AGCGCCCTTCCCGCTGGCTGTGATCCAAAATCCCTTCAGCAATGGTGGCAGTCCGGCGGCCGAGGCTGTCAGCGGGGAGGCACGATTTGC
CTATTTCCCAGCGTCCAGTGTGGGAGATACTACGGCTGTGTCCGTACAGACCACAGACCAGAGCTTGCAGGCTGGAGGCCAGTTCTACGT
CATGATGACGCCCCAGGATGTGCTTCAGACAGGAACACAGAGGACGATCGCCCCCCGGACACACCCTTACTCTCCAAAAATTGATGGAAC
CAGAACACCCCGAGATGAGAGGAGAAGAGCCCAGCACAACGAAGGTGGCCGGACTGTGCCATGCTGCTCCAGACCCAAGGTGGCAGCTCT
CACTGCGGGGACCCTGCTACTTCTGACAGCCATCGGGGCGGCATCCTGGGCCATTGTGGCTGTTCTCCTCAGGAGTGACCAGGAGCCGCT
GTACCCAGTGCAGGTCAGCTCTGCGGACGCTCGGCTCATGGTCTTTGACAAGACGGAAGGGACGTGGCGGCTGCTGTGCTCCTCGCGCTC
CAACGCCAGGGTAGCCGGACTCAGCTGCGAGGAGATGGGCTTCCTCAGGGCACTGACCCACTCCGAGCTGGACGTGCGAACGGCGGGCGC
CAATGGCACGTCGGGCTTCTTCTGTGTGGACGAGGGGAGGCTGCCCCACACCCAGAGGCTGCTGGAGGTCATCTCCGTGTGTGATTGCCC
CAGAGGCCGTTTCTTGGCCGCCATCTGCCAAGACTGTGGCCGCAGGAAGCTGCCCGTGGACCGCATCGTGGGAGGCCGGGACACCAGCTT
GGGCCGGTGGCCGTGGCAAGTCAGCCTTCGCTATGATGGAGCACACCTCTGTGGGGGATCCCTGCTCTCCGGGGACTGGGTGCTGACAGC
CGCCCACTGCTTCCCGGAGCGGAACCGGGTCCTGTCCCGATGGCGAGTGTTTGCCGGTGCCGTGGCCCAGGCCTCTCCCCACGGTCTGCA
GCTGGGGGTGCAGGCTGTGGTCTACCACGGGGGCTATCTTCCCTTTCGGGACCCCAACAGCGAGGAGAACAGCAACGATATTGCCCTGGT
CCACCTCTCCAGTCCCCTGCCCCTCACAGAATACATCCAGCCTGTGTGCCTCCCAGCTGCCGGCCAGGCCCTGGTGGATGGCAAGATCTG
TACCGTGACGGGCTGGGGCAACACGCAGTACTATGGCCAACAGGCCGGGGTACTCCAGGAGGCTCGAGTCCCCATAATCAGCAATGATGT
CTGCAATGGCGCTGACTTCTATGGAAACCAGATCAAGCCCAAGATGTTCTGTGCTGGCTACCCCGAGGGTGGCATTGATGCCTGCCAGGG
CGACAGCGGTGGTCCCTTTGTGTGTGAGGACAGCATCTCTCGGACGCCACGTTGGCGGCTGTGTGGCATTGTGAGTTGGGGCACTGGCTG
TGCCCTGGCCCAGAAGCCAGGCGTCTACACCAAAGTCAGTGACTTCCGGGAGTGGATCTTCCAGGCCATAAAGACTCACTCCGAAGCCAG
CGGCATGGTGACCCAGCTCTGACCGGTGGCTTCTCGCTGCGCAGCCTCCAGGGCCCGAGGTGATCCCGGTGGTGGGATCCACGCTGGGCC
TAGGATGGGACGTTTTTCTTCTTGGGCCCGGTCCACAGGTCCAAGGACACCCTCCCTCCAGGGTCCTCTCTTCCACAGTGGCGGGCCCAC
TCAGCCCCGAGACCACCCAACCTCACCCTCCTGACCCCCATGTAAATATTGTTCTGCTGTCTGGGACTCCTGTCTAGGTGCCCCTGATGA

>97121_97121_2_USF2-HPN_USF2_chr19_35762044_ENST00000222305_HPN_chr19_35540193_ENST00000392226_length(amino acids)=654AA_BP=242
MDMLDPGLDPAASATAAAAASHDKGPEAEEGVELQEGGDGPGAEEQTAVAITSVQQAAFGDHNIQYQFRTETNGGQVTYRVVQVTDGQLD
GQGDTAGAVSVVSTAAFAGGQQAVTQVGVDGAAQRPGPAAASVPPGPAAPFPLAVIQNPFSNGGSPAAEAVSGEARFAYFPASSVGDTTA
VSVQTTDQSLQAGGQFYVMMTPQDVLQTGTQRTIAPRTHPYSPKIDGTRTPRDERRRAQHNEGGRTVPCCSRPKVAALTAGTLLLLTAIG
AASWAIVAVLLRSDQEPLYPVQVSSADARLMVFDKTEGTWRLLCSSRSNARVAGLSCEEMGFLRALTHSELDVRTAGANGTSGFFCVDEG
RLPHTQRLLEVISVCDCPRGRFLAAICQDCGRRKLPVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLS
RWRVFAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYG
QQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKV

--------------------------------------------------------------
>97121_97121_3_USF2-HPN_USF2_chr19_35762044_ENST00000343550_HPN_chr19_35540193_ENST00000262626_length(transcript)=2172nt_BP=650nt
CTCCTGCCGCGCGGCGTGAGCGCCGGGCTCGGGGCCCCCCCGGCCGCCCGCCCCCTCCCCTCCCTCCCTCCCCTCCCCTCCCCTCCCCCC
CGGGCCCCGCGCCCCCCCCGCCCCCGCCCCCCCCATGGACATGCTGGACCCGGGTCTGGATCCCGCTGCCTCGGCCACCGCTGCTGCCGC
CGCCAGCCACGACAAGGGACCCGAGGCGGAGGAGGGCGTCGAGCTGCAGGAAGGCGGGGACGGCCCAGGAGCGGAGGAGCAGACAGCGGT
GGCCATCACCAGCGTCCAGCAGGCGGCGTTCGGCGACCACAACATCCAGTACCAGTTCCGCACAGAGACAAATGGAGGACAGGCTGTGAT
CCAAAATCCCTTCAGCAATGGTGGCAGTCCGGCGGCCGAGGCTGTCAGCGGGGAGGCACGATTTGCCTATTTCCCAGCGTCCAGTGTGGG
AGATACTACGGCTGTGTCCGTACAGACCACAGACCAGAGCTTGCAGGCTGGAGGCCAGTTCTACGTCATGATGACGCCCCAGGATGTGCT
TCAGACAGGAACACAGAGGACGATCGCCCCCCGGACACACCCTTACTCTCCAAAAATTGATGGAACCAGAACACCCCGAGATGAGAGGAG
AAGAGCCCAGCACAACGAAGGTGGCCGGACTGTGCCATGCTGCTCCAGACCCAAGGTGGCAGCTCTCACTGCGGGGACCCTGCTACTTCT
GACAGCCATCGGGGCGGCATCCTGGGCCATTGTGGCTGTTCTCCTCAGGAGTGACCAGGAGCCGCTGTACCCAGTGCAGGTCAGCTCTGC
GGACGCTCGGCTCATGGTCTTTGACAAGACGGAAGGGACGTGGCGGCTGCTGTGCTCCTCGCGCTCCAACGCCAGGGTAGCCGGACTCAG
CTGCGAGGAGATGGGCTTCCTCAGGGCACTGACCCACTCCGAGCTGGACGTGCGAACGGCGGGCGCCAATGGCACGTCGGGCTTCTTCTG
TGTGGACGAGGGGAGGCTGCCCCACACCCAGAGGCTGCTGGAGGTCATCTCCGTGTGTGATTGCCCCAGAGGCCGTTTCTTGGCCGCCAT
CTGCCAAGACTGTGGCCGCAGGAAGCTGCCCGTGGACCGCATCGTGGGAGGCCGGGACACCAGCTTGGGCCGGTGGCCGTGGCAAGTCAG
CCTTCGCTATGATGGAGCACACCTCTGTGGGGGATCCCTGCTCTCCGGGGACTGGGTGCTGACAGCCGCCCACTGCTTCCCGGAGCGGAA
CCGGGTCCTGTCCCGATGGCGAGTGTTTGCCGGTGCCGTGGCCCAGGCCTCTCCCCACGGTCTGCAGCTGGGGGTGCAGGCTGTGGTCTA
CCACGGGGGCTATCTTCCCTTTCGGGACCCCAACAGCGAGGAGAACAGCAACGATATTGCCCTGGTCCACCTCTCCAGTCCCCTGCCCCT
CACAGAATACATCCAGCCTGTGTGCCTCCCAGCTGCCGGCCAGGCCCTGGTGGATGGCAAGATCTGTACCGTGACGGGCTGGGGCAACAC
GCAGTACTATGGCCAACAGGCCGGGGTACTCCAGGAGGCTCGAGTCCCCATAATCAGCAATGATGTCTGCAATGGCGCTGACTTCTATGG
AAACCAGATCAAGCCCAAGATGTTCTGTGCTGGCTACCCCGAGGGTGGCATTGATGCCTGCCAGGGCGACAGCGGTGGTCCCTTTGTGTG
TGAGGACAGCATCTCTCGGACGCCACGTTGGCGGCTGTGTGGCATTGTGAGTTGGGGCACTGGCTGTGCCCTGGCCCAGAAGCCAGGCGT
CTACACCAAAGTCAGTGACTTCCGGGAGTGGATCTTCCAGGCCATAAAGACTCACTCCGAAGCCAGCGGCATGGTGACCCAGCTCTGACC
GGTGGCTTCTCGCTGCGCAGCCTCCAGGGCCCGAGGTGATCCCGGTGGTGGGATCCACGCTGGGCCTAGGATGGGACGTTTTTCTTCTTG
GGCCCGGTCCACAGGTCCAAGGACACCCTCCCTCCAGGGTCCTCTCTTCCACAGTGGCGGGCCCACTCAGCCCCGAGACCACCCAACCTC
ACCCTCCTGACCCCCATGTAAATATTGTTCTGCTGTCTGGGACTCCTGTCTAGGTGCCCCTGATGACGGGATGCTCTTTAAATAATAAAG

>97121_97121_3_USF2-HPN_USF2_chr19_35762044_ENST00000343550_HPN_chr19_35540193_ENST00000262626_length(amino acids)=587AA_BP=175
MDMLDPGLDPAASATAAAAASHDKGPEAEEGVELQEGGDGPGAEEQTAVAITSVQQAAFGDHNIQYQFRTETNGGQAVIQNPFSNGGSPA
AEAVSGEARFAYFPASSVGDTTAVSVQTTDQSLQAGGQFYVMMTPQDVLQTGTQRTIAPRTHPYSPKIDGTRTPRDERRRAQHNEGGRTV
PCCSRPKVAALTAGTLLLLTAIGAASWAIVAVLLRSDQEPLYPVQVSSADARLMVFDKTEGTWRLLCSSRSNARVAGLSCEEMGFLRALT
HSELDVRTAGANGTSGFFCVDEGRLPHTQRLLEVISVCDCPRGRFLAAICQDCGRRKLPVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGG
SLLSGDWVLTAAHCFPERNRVLSRWRVFAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPA
AGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWR

--------------------------------------------------------------
>97121_97121_4_USF2-HPN_USF2_chr19_35762044_ENST00000343550_HPN_chr19_35540193_ENST00000392226_length(transcript)=2172nt_BP=650nt
CTCCTGCCGCGCGGCGTGAGCGCCGGGCTCGGGGCCCCCCCGGCCGCCCGCCCCCTCCCCTCCCTCCCTCCCCTCCCCTCCCCTCCCCCC
CGGGCCCCGCGCCCCCCCCGCCCCCGCCCCCCCCATGGACATGCTGGACCCGGGTCTGGATCCCGCTGCCTCGGCCACCGCTGCTGCCGC
CGCCAGCCACGACAAGGGACCCGAGGCGGAGGAGGGCGTCGAGCTGCAGGAAGGCGGGGACGGCCCAGGAGCGGAGGAGCAGACAGCGGT
GGCCATCACCAGCGTCCAGCAGGCGGCGTTCGGCGACCACAACATCCAGTACCAGTTCCGCACAGAGACAAATGGAGGACAGGCTGTGAT
CCAAAATCCCTTCAGCAATGGTGGCAGTCCGGCGGCCGAGGCTGTCAGCGGGGAGGCACGATTTGCCTATTTCCCAGCGTCCAGTGTGGG
AGATACTACGGCTGTGTCCGTACAGACCACAGACCAGAGCTTGCAGGCTGGAGGCCAGTTCTACGTCATGATGACGCCCCAGGATGTGCT
TCAGACAGGAACACAGAGGACGATCGCCCCCCGGACACACCCTTACTCTCCAAAAATTGATGGAACCAGAACACCCCGAGATGAGAGGAG
AAGAGCCCAGCACAACGAAGGTGGCCGGACTGTGCCATGCTGCTCCAGACCCAAGGTGGCAGCTCTCACTGCGGGGACCCTGCTACTTCT
GACAGCCATCGGGGCGGCATCCTGGGCCATTGTGGCTGTTCTCCTCAGGAGTGACCAGGAGCCGCTGTACCCAGTGCAGGTCAGCTCTGC
GGACGCTCGGCTCATGGTCTTTGACAAGACGGAAGGGACGTGGCGGCTGCTGTGCTCCTCGCGCTCCAACGCCAGGGTAGCCGGACTCAG
CTGCGAGGAGATGGGCTTCCTCAGGGCACTGACCCACTCCGAGCTGGACGTGCGAACGGCGGGCGCCAATGGCACGTCGGGCTTCTTCTG
TGTGGACGAGGGGAGGCTGCCCCACACCCAGAGGCTGCTGGAGGTCATCTCCGTGTGTGATTGCCCCAGAGGCCGTTTCTTGGCCGCCAT
CTGCCAAGACTGTGGCCGCAGGAAGCTGCCCGTGGACCGCATCGTGGGAGGCCGGGACACCAGCTTGGGCCGGTGGCCGTGGCAAGTCAG
CCTTCGCTATGATGGAGCACACCTCTGTGGGGGATCCCTGCTCTCCGGGGACTGGGTGCTGACAGCCGCCCACTGCTTCCCGGAGCGGAA
CCGGGTCCTGTCCCGATGGCGAGTGTTTGCCGGTGCCGTGGCCCAGGCCTCTCCCCACGGTCTGCAGCTGGGGGTGCAGGCTGTGGTCTA
CCACGGGGGCTATCTTCCCTTTCGGGACCCCAACAGCGAGGAGAACAGCAACGATATTGCCCTGGTCCACCTCTCCAGTCCCCTGCCCCT
CACAGAATACATCCAGCCTGTGTGCCTCCCAGCTGCCGGCCAGGCCCTGGTGGATGGCAAGATCTGTACCGTGACGGGCTGGGGCAACAC
GCAGTACTATGGCCAACAGGCCGGGGTACTCCAGGAGGCTCGAGTCCCCATAATCAGCAATGATGTCTGCAATGGCGCTGACTTCTATGG
AAACCAGATCAAGCCCAAGATGTTCTGTGCTGGCTACCCCGAGGGTGGCATTGATGCCTGCCAGGGCGACAGCGGTGGTCCCTTTGTGTG
TGAGGACAGCATCTCTCGGACGCCACGTTGGCGGCTGTGTGGCATTGTGAGTTGGGGCACTGGCTGTGCCCTGGCCCAGAAGCCAGGCGT
CTACACCAAAGTCAGTGACTTCCGGGAGTGGATCTTCCAGGCCATAAAGACTCACTCCGAAGCCAGCGGCATGGTGACCCAGCTCTGACC
GGTGGCTTCTCGCTGCGCAGCCTCCAGGGCCCGAGGTGATCCCGGTGGTGGGATCCACGCTGGGCCTAGGATGGGACGTTTTTCTTCTTG
GGCCCGGTCCACAGGTCCAAGGACACCCTCCCTCCAGGGTCCTCTCTTCCACAGTGGCGGGCCCACTCAGCCCCGAGACCACCCAACCTC
ACCCTCCTGACCCCCATGTAAATATTGTTCTGCTGTCTGGGACTCCTGTCTAGGTGCCCCTGATGACGGGATGCTCTTTAAATAATAAAG

>97121_97121_4_USF2-HPN_USF2_chr19_35762044_ENST00000343550_HPN_chr19_35540193_ENST00000392226_length(amino acids)=587AA_BP=175
MDMLDPGLDPAASATAAAAASHDKGPEAEEGVELQEGGDGPGAEEQTAVAITSVQQAAFGDHNIQYQFRTETNGGQAVIQNPFSNGGSPA
AEAVSGEARFAYFPASSVGDTTAVSVQTTDQSLQAGGQFYVMMTPQDVLQTGTQRTIAPRTHPYSPKIDGTRTPRDERRRAQHNEGGRTV
PCCSRPKVAALTAGTLLLLTAIGAASWAIVAVLLRSDQEPLYPVQVSSADARLMVFDKTEGTWRLLCSSRSNARVAGLSCEEMGFLRALT
HSELDVRTAGANGTSGFFCVDEGRLPHTQRLLEVISVCDCPRGRFLAAICQDCGRRKLPVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGG
SLLSGDWVLTAAHCFPERNRVLSRWRVFAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPA
AGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWR

--------------------------------------------------------------
>97121_97121_5_USF2-HPN_USF2_chr19_35762044_ENST00000379134_HPN_chr19_35540193_ENST00000262626_length(transcript)=1856nt_BP=334nt
ATGGACATGCTGGACCCGGGTCTGGATCCCGCTGCCTCGGCCACCGCTGCTGCCGCCGCCAGCCACGACAAGGGACCCGAGGCGGAGGAG
GGCGTCGAGCTGCAGGAAGGCGGGGACGGCCCAGGAGCGGAGGAGCAGACAGCGGTGGCCATCACCAGCGTCCAGCAGGCGGCGTTCGGC
GACCACAACATCCAGTACCAGTTCCGCACAGAGACAAATGGAGGACAGACAGGAACACAGAGGACGATCGCCCCCCGGACACACCCTTAC
TCTCCAAAAATTGATGGAACCAGAACACCCCGAGATGAGAGGAGAAGAGCCCAGCACAACGAAGGTGGCCGGACTGTGCCATGCTGCTCC
AGACCCAAGGTGGCAGCTCTCACTGCGGGGACCCTGCTACTTCTGACAGCCATCGGGGCGGCATCCTGGGCCATTGTGGCTGTTCTCCTC
AGGAGTGACCAGGAGCCGCTGTACCCAGTGCAGGTCAGCTCTGCGGACGCTCGGCTCATGGTCTTTGACAAGACGGAAGGGACGTGGCGG
CTGCTGTGCTCCTCGCGCTCCAACGCCAGGGTAGCCGGACTCAGCTGCGAGGAGATGGGCTTCCTCAGGGCACTGACCCACTCCGAGCTG
GACGTGCGAACGGCGGGCGCCAATGGCACGTCGGGCTTCTTCTGTGTGGACGAGGGGAGGCTGCCCCACACCCAGAGGCTGCTGGAGGTC
ATCTCCGTGTGTGATTGCCCCAGAGGCCGTTTCTTGGCCGCCATCTGCCAAGACTGTGGCCGCAGGAAGCTGCCCGTGGACCGCATCGTG
GGAGGCCGGGACACCAGCTTGGGCCGGTGGCCGTGGCAAGTCAGCCTTCGCTATGATGGAGCACACCTCTGTGGGGGATCCCTGCTCTCC
GGGGACTGGGTGCTGACAGCCGCCCACTGCTTCCCGGAGCGGAACCGGGTCCTGTCCCGATGGCGAGTGTTTGCCGGTGCCGTGGCCCAG
GCCTCTCCCCACGGTCTGCAGCTGGGGGTGCAGGCTGTGGTCTACCACGGGGGCTATCTTCCCTTTCGGGACCCCAACAGCGAGGAGAAC
AGCAACGATATTGCCCTGGTCCACCTCTCCAGTCCCCTGCCCCTCACAGAATACATCCAGCCTGTGTGCCTCCCAGCTGCCGGCCAGGCC
CTGGTGGATGGCAAGATCTGTACCGTGACGGGCTGGGGCAACACGCAGTACTATGGCCAACAGGCCGGGGTACTCCAGGAGGCTCGAGTC
CCCATAATCAGCAATGATGTCTGCAATGGCGCTGACTTCTATGGAAACCAGATCAAGCCCAAGATGTTCTGTGCTGGCTACCCCGAGGGT
GGCATTGATGCCTGCCAGGGCGACAGCGGTGGTCCCTTTGTGTGTGAGGACAGCATCTCTCGGACGCCACGTTGGCGGCTGTGTGGCATT
GTGAGTTGGGGCACTGGCTGTGCCCTGGCCCAGAAGCCAGGCGTCTACACCAAAGTCAGTGACTTCCGGGAGTGGATCTTCCAGGCCATA
AAGACTCACTCCGAAGCCAGCGGCATGGTGACCCAGCTCTGACCGGTGGCTTCTCGCTGCGCAGCCTCCAGGGCCCGAGGTGATCCCGGT
GGTGGGATCCACGCTGGGCCTAGGATGGGACGTTTTTCTTCTTGGGCCCGGTCCACAGGTCCAAGGACACCCTCCCTCCAGGGTCCTCTC
TTCCACAGTGGCGGGCCCACTCAGCCCCGAGACCACCCAACCTCACCCTCCTGACCCCCATGTAAATATTGTTCTGCTGTCTGGGACTCC

>97121_97121_5_USF2-HPN_USF2_chr19_35762044_ENST00000379134_HPN_chr19_35540193_ENST00000262626_length(amino acids)=523AA_BP=111
MDMLDPGLDPAASATAAAAASHDKGPEAEEGVELQEGGDGPGAEEQTAVAITSVQQAAFGDHNIQYQFRTETNGGQTGTQRTIAPRTHPY
SPKIDGTRTPRDERRRAQHNEGGRTVPCCSRPKVAALTAGTLLLLTAIGAASWAIVAVLLRSDQEPLYPVQVSSADARLMVFDKTEGTWR
LLCSSRSNARVAGLSCEEMGFLRALTHSELDVRTAGANGTSGFFCVDEGRLPHTQRLLEVISVCDCPRGRFLAAICQDCGRRKLPVDRIV
GGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEEN
SNDIALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFCAGYPEG

--------------------------------------------------------------
>97121_97121_6_USF2-HPN_USF2_chr19_35762044_ENST00000379134_HPN_chr19_35540193_ENST00000392226_length(transcript)=1856nt_BP=334nt
ATGGACATGCTGGACCCGGGTCTGGATCCCGCTGCCTCGGCCACCGCTGCTGCCGCCGCCAGCCACGACAAGGGACCCGAGGCGGAGGAG
GGCGTCGAGCTGCAGGAAGGCGGGGACGGCCCAGGAGCGGAGGAGCAGACAGCGGTGGCCATCACCAGCGTCCAGCAGGCGGCGTTCGGC
GACCACAACATCCAGTACCAGTTCCGCACAGAGACAAATGGAGGACAGACAGGAACACAGAGGACGATCGCCCCCCGGACACACCCTTAC
TCTCCAAAAATTGATGGAACCAGAACACCCCGAGATGAGAGGAGAAGAGCCCAGCACAACGAAGGTGGCCGGACTGTGCCATGCTGCTCC
AGACCCAAGGTGGCAGCTCTCACTGCGGGGACCCTGCTACTTCTGACAGCCATCGGGGCGGCATCCTGGGCCATTGTGGCTGTTCTCCTC
AGGAGTGACCAGGAGCCGCTGTACCCAGTGCAGGTCAGCTCTGCGGACGCTCGGCTCATGGTCTTTGACAAGACGGAAGGGACGTGGCGG
CTGCTGTGCTCCTCGCGCTCCAACGCCAGGGTAGCCGGACTCAGCTGCGAGGAGATGGGCTTCCTCAGGGCACTGACCCACTCCGAGCTG
GACGTGCGAACGGCGGGCGCCAATGGCACGTCGGGCTTCTTCTGTGTGGACGAGGGGAGGCTGCCCCACACCCAGAGGCTGCTGGAGGTC
ATCTCCGTGTGTGATTGCCCCAGAGGCCGTTTCTTGGCCGCCATCTGCCAAGACTGTGGCCGCAGGAAGCTGCCCGTGGACCGCATCGTG
GGAGGCCGGGACACCAGCTTGGGCCGGTGGCCGTGGCAAGTCAGCCTTCGCTATGATGGAGCACACCTCTGTGGGGGATCCCTGCTCTCC
GGGGACTGGGTGCTGACAGCCGCCCACTGCTTCCCGGAGCGGAACCGGGTCCTGTCCCGATGGCGAGTGTTTGCCGGTGCCGTGGCCCAG
GCCTCTCCCCACGGTCTGCAGCTGGGGGTGCAGGCTGTGGTCTACCACGGGGGCTATCTTCCCTTTCGGGACCCCAACAGCGAGGAGAAC
AGCAACGATATTGCCCTGGTCCACCTCTCCAGTCCCCTGCCCCTCACAGAATACATCCAGCCTGTGTGCCTCCCAGCTGCCGGCCAGGCC
CTGGTGGATGGCAAGATCTGTACCGTGACGGGCTGGGGCAACACGCAGTACTATGGCCAACAGGCCGGGGTACTCCAGGAGGCTCGAGTC
CCCATAATCAGCAATGATGTCTGCAATGGCGCTGACTTCTATGGAAACCAGATCAAGCCCAAGATGTTCTGTGCTGGCTACCCCGAGGGT
GGCATTGATGCCTGCCAGGGCGACAGCGGTGGTCCCTTTGTGTGTGAGGACAGCATCTCTCGGACGCCACGTTGGCGGCTGTGTGGCATT
GTGAGTTGGGGCACTGGCTGTGCCCTGGCCCAGAAGCCAGGCGTCTACACCAAAGTCAGTGACTTCCGGGAGTGGATCTTCCAGGCCATA
AAGACTCACTCCGAAGCCAGCGGCATGGTGACCCAGCTCTGACCGGTGGCTTCTCGCTGCGCAGCCTCCAGGGCCCGAGGTGATCCCGGT
GGTGGGATCCACGCTGGGCCTAGGATGGGACGTTTTTCTTCTTGGGCCCGGTCCACAGGTCCAAGGACACCCTCCCTCCAGGGTCCTCTC
TTCCACAGTGGCGGGCCCACTCAGCCCCGAGACCACCCAACCTCACCCTCCTGACCCCCATGTAAATATTGTTCTGCTGTCTGGGACTCC

>97121_97121_6_USF2-HPN_USF2_chr19_35762044_ENST00000379134_HPN_chr19_35540193_ENST00000392226_length(amino acids)=523AA_BP=111
MDMLDPGLDPAASATAAAAASHDKGPEAEEGVELQEGGDGPGAEEQTAVAITSVQQAAFGDHNIQYQFRTETNGGQTGTQRTIAPRTHPY
SPKIDGTRTPRDERRRAQHNEGGRTVPCCSRPKVAALTAGTLLLLTAIGAASWAIVAVLLRSDQEPLYPVQVSSADARLMVFDKTEGTWR
LLCSSRSNARVAGLSCEEMGFLRALTHSELDVRTAGANGTSGFFCVDEGRLPHTQRLLEVISVCDCPRGRFLAAICQDCGRRKLPVDRIV
GGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEEN
SNDIALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFCAGYPEG

--------------------------------------------------------------
>97121_97121_7_USF2-HPN_USF2_chr19_35762044_ENST00000594064_HPN_chr19_35540193_ENST00000262626_length(transcript)=2243nt_BP=721nt
ATGCTGGACCCGGGTCTGGATCCCGCTGCCTCGGCCACCGCTGCTGCCGCCGCCAGCCACGACAAGGGACCCGAGGCGGAGGAGGGCGTC
GAGCTGCAGGAAGGCGGGGACGGCCCAGGAGCGGAGGAGCAGACAGCGGTGGCCATCACCAGCGTCCAGCAGGCGGCGTTCGGCGACCAC
AACATCCAGTACCAGTTCCGCACAGAGACAAATGGAGGACAGGTGACATACCGCGTAGTCCAGGTGACTGATGGTCAGCTGGACGGCCAG
GGCGACACAGCTGGCGCCGTCAGCGTCGTGTCCACCGCTGCCTTCGCGGGGGGGCAGCAGGCTGTGACCCAGGTGGGTGTGGACGGGGCA
GCCCAGCGCCCGGGCCCCGCCGCTGCCTCTGTGCCCCCAGGTCCTGCAGCGCCCTTCCCGCTGGCTGTGATCCAAAATCCCTTCAGCAAT
GGTGGCAGTCCGGCGGCCGAGGCTGTCAGCGGGGAGGCACGATTTGCCTATTTCCCAGCGTCCAGTGTGGGAGATACTACGGCTGTGTCC
GTACAGACCACAGACCAGAGCTTGCAGGCTGGAGGCCAGTTCTACGTCATGATGACGCCCCAGGATGTGCTTCAGACAGGAACACAGAGG
ACGATCGCCCCCCGGACACACCCTTACTCTCCAAAAATTGATGGAACCAGAACACCCCGAGATGAGAGGAGAAGAGCCCAGCACAACGAA
GGTGGCCGGACTGTGCCATGCTGCTCCAGACCCAAGGTGGCAGCTCTCACTGCGGGGACCCTGCTACTTCTGACAGCCATCGGGGCGGCA
TCCTGGGCCATTGTGGCTGTTCTCCTCAGGAGTGACCAGGAGCCGCTGTACCCAGTGCAGGTCAGCTCTGCGGACGCTCGGCTCATGGTC
TTTGACAAGACGGAAGGGACGTGGCGGCTGCTGTGCTCCTCGCGCTCCAACGCCAGGGTAGCCGGACTCAGCTGCGAGGAGATGGGCTTC
CTCAGGGCACTGACCCACTCCGAGCTGGACGTGCGAACGGCGGGCGCCAATGGCACGTCGGGCTTCTTCTGTGTGGACGAGGGGAGGCTG
CCCCACACCCAGAGGCTGCTGGAGGTCATCTCCGTGTGTGATTGCCCCAGAGGCCGTTTCTTGGCCGCCATCTGCCAAGACTGTGGCCGC
AGGAAGCTGCCCGTGGACCGCATCGTGGGAGGCCGGGACACCAGCTTGGGCCGGTGGCCGTGGCAAGTCAGCCTTCGCTATGATGGAGCA
CACCTCTGTGGGGGATCCCTGCTCTCCGGGGACTGGGTGCTGACAGCCGCCCACTGCTTCCCGGAGCGGAACCGGGTCCTGTCCCGATGG
CGAGTGTTTGCCGGTGCCGTGGCCCAGGCCTCTCCCCACGGTCTGCAGCTGGGGGTGCAGGCTGTGGTCTACCACGGGGGCTATCTTCCC
TTTCGGGACCCCAACAGCGAGGAGAACAGCAACGATATTGCCCTGGTCCACCTCTCCAGTCCCCTGCCCCTCACAGAATACATCCAGCCT
GTGTGCCTCCCAGCTGCCGGCCAGGCCCTGGTGGATGGCAAGATCTGTACCGTGACGGGCTGGGGCAACACGCAGTACTATGGCCAACAG
GCCGGGGTACTCCAGGAGGCTCGAGTCCCCATAATCAGCAATGATGTCTGCAATGGCGCTGACTTCTATGGAAACCAGATCAAGCCCAAG
ATGTTCTGTGCTGGCTACCCCGAGGGTGGCATTGATGCCTGCCAGGGCGACAGCGGTGGTCCCTTTGTGTGTGAGGACAGCATCTCTCGG
ACGCCACGTTGGCGGCTGTGTGGCATTGTGAGTTGGGGCACTGGCTGTGCCCTGGCCCAGAAGCCAGGCGTCTACACCAAAGTCAGTGAC
TTCCGGGAGTGGATCTTCCAGGCCATAAAGACTCACTCCGAAGCCAGCGGCATGGTGACCCAGCTCTGACCGGTGGCTTCTCGCTGCGCA
GCCTCCAGGGCCCGAGGTGATCCCGGTGGTGGGATCCACGCTGGGCCTAGGATGGGACGTTTTTCTTCTTGGGCCCGGTCCACAGGTCCA
AGGACACCCTCCCTCCAGGGTCCTCTCTTCCACAGTGGCGGGCCCACTCAGCCCCGAGACCACCCAACCTCACCCTCCTGACCCCCATGT

>97121_97121_7_USF2-HPN_USF2_chr19_35762044_ENST00000594064_HPN_chr19_35540193_ENST00000262626_length(amino acids)=652AA_BP=240
MLDPGLDPAASATAAAAASHDKGPEAEEGVELQEGGDGPGAEEQTAVAITSVQQAAFGDHNIQYQFRTETNGGQVTYRVVQVTDGQLDGQ
GDTAGAVSVVSTAAFAGGQQAVTQVGVDGAAQRPGPAAASVPPGPAAPFPLAVIQNPFSNGGSPAAEAVSGEARFAYFPASSVGDTTAVS
VQTTDQSLQAGGQFYVMMTPQDVLQTGTQRTIAPRTHPYSPKIDGTRTPRDERRRAQHNEGGRTVPCCSRPKVAALTAGTLLLLTAIGAA
SWAIVAVLLRSDQEPLYPVQVSSADARLMVFDKTEGTWRLLCSSRSNARVAGLSCEEMGFLRALTHSELDVRTAGANGTSGFFCVDEGRL
PHTQRLLEVISVCDCPRGRFLAAICQDCGRRKLPVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRW
RVFAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQ
AGVLQEARVPIISNDVCNGADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSD

--------------------------------------------------------------
>97121_97121_8_USF2-HPN_USF2_chr19_35762044_ENST00000594064_HPN_chr19_35540193_ENST00000392226_length(transcript)=2243nt_BP=721nt
ATGCTGGACCCGGGTCTGGATCCCGCTGCCTCGGCCACCGCTGCTGCCGCCGCCAGCCACGACAAGGGACCCGAGGCGGAGGAGGGCGTC
GAGCTGCAGGAAGGCGGGGACGGCCCAGGAGCGGAGGAGCAGACAGCGGTGGCCATCACCAGCGTCCAGCAGGCGGCGTTCGGCGACCAC
AACATCCAGTACCAGTTCCGCACAGAGACAAATGGAGGACAGGTGACATACCGCGTAGTCCAGGTGACTGATGGTCAGCTGGACGGCCAG
GGCGACACAGCTGGCGCCGTCAGCGTCGTGTCCACCGCTGCCTTCGCGGGGGGGCAGCAGGCTGTGACCCAGGTGGGTGTGGACGGGGCA
GCCCAGCGCCCGGGCCCCGCCGCTGCCTCTGTGCCCCCAGGTCCTGCAGCGCCCTTCCCGCTGGCTGTGATCCAAAATCCCTTCAGCAAT
GGTGGCAGTCCGGCGGCCGAGGCTGTCAGCGGGGAGGCACGATTTGCCTATTTCCCAGCGTCCAGTGTGGGAGATACTACGGCTGTGTCC
GTACAGACCACAGACCAGAGCTTGCAGGCTGGAGGCCAGTTCTACGTCATGATGACGCCCCAGGATGTGCTTCAGACAGGAACACAGAGG
ACGATCGCCCCCCGGACACACCCTTACTCTCCAAAAATTGATGGAACCAGAACACCCCGAGATGAGAGGAGAAGAGCCCAGCACAACGAA
GGTGGCCGGACTGTGCCATGCTGCTCCAGACCCAAGGTGGCAGCTCTCACTGCGGGGACCCTGCTACTTCTGACAGCCATCGGGGCGGCA
TCCTGGGCCATTGTGGCTGTTCTCCTCAGGAGTGACCAGGAGCCGCTGTACCCAGTGCAGGTCAGCTCTGCGGACGCTCGGCTCATGGTC
TTTGACAAGACGGAAGGGACGTGGCGGCTGCTGTGCTCCTCGCGCTCCAACGCCAGGGTAGCCGGACTCAGCTGCGAGGAGATGGGCTTC
CTCAGGGCACTGACCCACTCCGAGCTGGACGTGCGAACGGCGGGCGCCAATGGCACGTCGGGCTTCTTCTGTGTGGACGAGGGGAGGCTG
CCCCACACCCAGAGGCTGCTGGAGGTCATCTCCGTGTGTGATTGCCCCAGAGGCCGTTTCTTGGCCGCCATCTGCCAAGACTGTGGCCGC
AGGAAGCTGCCCGTGGACCGCATCGTGGGAGGCCGGGACACCAGCTTGGGCCGGTGGCCGTGGCAAGTCAGCCTTCGCTATGATGGAGCA
CACCTCTGTGGGGGATCCCTGCTCTCCGGGGACTGGGTGCTGACAGCCGCCCACTGCTTCCCGGAGCGGAACCGGGTCCTGTCCCGATGG
CGAGTGTTTGCCGGTGCCGTGGCCCAGGCCTCTCCCCACGGTCTGCAGCTGGGGGTGCAGGCTGTGGTCTACCACGGGGGCTATCTTCCC
TTTCGGGACCCCAACAGCGAGGAGAACAGCAACGATATTGCCCTGGTCCACCTCTCCAGTCCCCTGCCCCTCACAGAATACATCCAGCCT
GTGTGCCTCCCAGCTGCCGGCCAGGCCCTGGTGGATGGCAAGATCTGTACCGTGACGGGCTGGGGCAACACGCAGTACTATGGCCAACAG
GCCGGGGTACTCCAGGAGGCTCGAGTCCCCATAATCAGCAATGATGTCTGCAATGGCGCTGACTTCTATGGAAACCAGATCAAGCCCAAG
ATGTTCTGTGCTGGCTACCCCGAGGGTGGCATTGATGCCTGCCAGGGCGACAGCGGTGGTCCCTTTGTGTGTGAGGACAGCATCTCTCGG
ACGCCACGTTGGCGGCTGTGTGGCATTGTGAGTTGGGGCACTGGCTGTGCCCTGGCCCAGAAGCCAGGCGTCTACACCAAAGTCAGTGAC
TTCCGGGAGTGGATCTTCCAGGCCATAAAGACTCACTCCGAAGCCAGCGGCATGGTGACCCAGCTCTGACCGGTGGCTTCTCGCTGCGCA
GCCTCCAGGGCCCGAGGTGATCCCGGTGGTGGGATCCACGCTGGGCCTAGGATGGGACGTTTTTCTTCTTGGGCCCGGTCCACAGGTCCA
AGGACACCCTCCCTCCAGGGTCCTCTCTTCCACAGTGGCGGGCCCACTCAGCCCCGAGACCACCCAACCTCACCCTCCTGACCCCCATGT

>97121_97121_8_USF2-HPN_USF2_chr19_35762044_ENST00000594064_HPN_chr19_35540193_ENST00000392226_length(amino acids)=652AA_BP=240
MLDPGLDPAASATAAAAASHDKGPEAEEGVELQEGGDGPGAEEQTAVAITSVQQAAFGDHNIQYQFRTETNGGQVTYRVVQVTDGQLDGQ
GDTAGAVSVVSTAAFAGGQQAVTQVGVDGAAQRPGPAAASVPPGPAAPFPLAVIQNPFSNGGSPAAEAVSGEARFAYFPASSVGDTTAVS
VQTTDQSLQAGGQFYVMMTPQDVLQTGTQRTIAPRTHPYSPKIDGTRTPRDERRRAQHNEGGRTVPCCSRPKVAALTAGTLLLLTAIGAA
SWAIVAVLLRSDQEPLYPVQVSSADARLMVFDKTEGTWRLLCSSRSNARVAGLSCEEMGFLRALTHSELDVRTAGANGTSGFFCVDEGRL
PHTQRLLEVISVCDCPRGRFLAAICQDCGRRKLPVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRW
RVFAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQ
AGVLQEARVPIISNDVCNGADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSD

--------------------------------------------------------------
>97121_97121_9_USF2-HPN_USF2_chr19_35762044_ENST00000595068_HPN_chr19_35540193_ENST00000262626_length(transcript)=2286nt_BP=764nt
CCCCGGGCCCCGCGCCCCCCCCGCCCCCGCCCCCCCCATGGACATGCTGGACCCGGGTCTGGATCCCGCTGCCTCGGCCACCGCTGCTGC
CGCCGCCAGCCACGACAAGGGACCCGAGGCGGAGGAGGGCGTCGAGCTGCAGGAAGGCGGGGACGGCCCAGGAGCGGAGGAGCAGACAGC
GGTGGCCATCACCAGCGTCCAGCAGGCGGCGTTCGGCGACCACAACATCCAGTACCAGTTCCGCACAGAGACAAATGGAGGACAGGTGAC
ATACCGCGTAGTCCAGGTGACTGATGGTCAGCTGGACGGCCAGGGCGACACAGCTGGCGCCGTCAGCGTCGTGTCCACCGCTGCCTTCGC
GGGGGGGCAGCAGGCTGTGACCCAGGTGGGTGTGGACGGGGCAGCCCAGCGCCCGGGCCCCGCCGCTGCCTCTGTGCCCCCAGGTCCTGC
AGCGCCCTTCCCGCTGGCTGTGATCCAAAATCCCTTCAGCAATGGTGGCAGTCCGGCGGCCGAGGCTGTCAGCGGGGAGGCACGATTTGC
CTATTTCCCAGCGTCCAGTGTGGGAGATACTACGGCTGTGTCCGTACAGACCACAGACCAGAGCTTGCAGGCTGGAGGCCAGTTCTACGT
CATGATGACGCCCCAGGATGTGCTTCAGACAGGAACACAGAGGACGATCGCCCCCCGGACACACCCTTACTCTCCAAAAATTGATGGAAC
CAGAACACCCCGAGATGAGAGGAGAAGAGCCCAGCACAACGAAGGTGGCCGGACTGTGCCATGCTGCTCCAGACCCAAGGTGGCAGCTCT
CACTGCGGGGACCCTGCTACTTCTGACAGCCATCGGGGCGGCATCCTGGGCCATTGTGGCTGTTCTCCTCAGGAGTGACCAGGAGCCGCT
GTACCCAGTGCAGGTCAGCTCTGCGGACGCTCGGCTCATGGTCTTTGACAAGACGGAAGGGACGTGGCGGCTGCTGTGCTCCTCGCGCTC
CAACGCCAGGGTAGCCGGACTCAGCTGCGAGGAGATGGGCTTCCTCAGGGCACTGACCCACTCCGAGCTGGACGTGCGAACGGCGGGCGC
CAATGGCACGTCGGGCTTCTTCTGTGTGGACGAGGGGAGGCTGCCCCACACCCAGAGGCTGCTGGAGGTCATCTCCGTGTGTGATTGCCC
CAGAGGCCGTTTCTTGGCCGCCATCTGCCAAGACTGTGGCCGCAGGAAGCTGCCCGTGGACCGCATCGTGGGAGGCCGGGACACCAGCTT
GGGCCGGTGGCCGTGGCAAGTCAGCCTTCGCTATGATGGAGCACACCTCTGTGGGGGATCCCTGCTCTCCGGGGACTGGGTGCTGACAGC
CGCCCACTGCTTCCCGGAGCGGAACCGGGTCCTGTCCCGATGGCGAGTGTTTGCCGGTGCCGTGGCCCAGGCCTCTCCCCACGGTCTGCA
GCTGGGGGTGCAGGCTGTGGTCTACCACGGGGGCTATCTTCCCTTTCGGGACCCCAACAGCGAGGAGAACAGCAACGATATTGCCCTGGT
CCACCTCTCCAGTCCCCTGCCCCTCACAGAATACATCCAGCCTGTGTGCCTCCCAGCTGCCGGCCAGGCCCTGGTGGATGGCAAGATCTG
TACCGTGACGGGCTGGGGCAACACGCAGTACTATGGCCAACAGGCCGGGGTACTCCAGGAGGCTCGAGTCCCCATAATCAGCAATGATGT
CTGCAATGGCGCTGACTTCTATGGAAACCAGATCAAGCCCAAGATGTTCTGTGCTGGCTACCCCGAGGGTGGCATTGATGCCTGCCAGGG
CGACAGCGGTGGTCCCTTTGTGTGTGAGGACAGCATCTCTCGGACGCCACGTTGGCGGCTGTGTGGCATTGTGAGTTGGGGCACTGGCTG
TGCCCTGGCCCAGAAGCCAGGCGTCTACACCAAAGTCAGTGACTTCCGGGAGTGGATCTTCCAGGCCATAAAGACTCACTCCGAAGCCAG
CGGCATGGTGACCCAGCTCTGACCGGTGGCTTCTCGCTGCGCAGCCTCCAGGGCCCGAGGTGATCCCGGTGGTGGGATCCACGCTGGGCC
TAGGATGGGACGTTTTTCTTCTTGGGCCCGGTCCACAGGTCCAAGGACACCCTCCCTCCAGGGTCCTCTCTTCCACAGTGGCGGGCCCAC
TCAGCCCCGAGACCACCCAACCTCACCCTCCTGACCCCCATGTAAATATTGTTCTGCTGTCTGGGACTCCTGTCTAGGTGCCCCTGATGA

>97121_97121_9_USF2-HPN_USF2_chr19_35762044_ENST00000595068_HPN_chr19_35540193_ENST00000262626_length(amino acids)=654AA_BP=242
MDMLDPGLDPAASATAAAAASHDKGPEAEEGVELQEGGDGPGAEEQTAVAITSVQQAAFGDHNIQYQFRTETNGGQVTYRVVQVTDGQLD
GQGDTAGAVSVVSTAAFAGGQQAVTQVGVDGAAQRPGPAAASVPPGPAAPFPLAVIQNPFSNGGSPAAEAVSGEARFAYFPASSVGDTTA
VSVQTTDQSLQAGGQFYVMMTPQDVLQTGTQRTIAPRTHPYSPKIDGTRTPRDERRRAQHNEGGRTVPCCSRPKVAALTAGTLLLLTAIG
AASWAIVAVLLRSDQEPLYPVQVSSADARLMVFDKTEGTWRLLCSSRSNARVAGLSCEEMGFLRALTHSELDVRTAGANGTSGFFCVDEG
RLPHTQRLLEVISVCDCPRGRFLAAICQDCGRRKLPVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLS
RWRVFAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYG
QQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKV

--------------------------------------------------------------
>97121_97121_10_USF2-HPN_USF2_chr19_35762044_ENST00000595068_HPN_chr19_35540193_ENST00000392226_length(transcript)=2286nt_BP=764nt
CCCCGGGCCCCGCGCCCCCCCCGCCCCCGCCCCCCCCATGGACATGCTGGACCCGGGTCTGGATCCCGCTGCCTCGGCCACCGCTGCTGC
CGCCGCCAGCCACGACAAGGGACCCGAGGCGGAGGAGGGCGTCGAGCTGCAGGAAGGCGGGGACGGCCCAGGAGCGGAGGAGCAGACAGC
GGTGGCCATCACCAGCGTCCAGCAGGCGGCGTTCGGCGACCACAACATCCAGTACCAGTTCCGCACAGAGACAAATGGAGGACAGGTGAC
ATACCGCGTAGTCCAGGTGACTGATGGTCAGCTGGACGGCCAGGGCGACACAGCTGGCGCCGTCAGCGTCGTGTCCACCGCTGCCTTCGC
GGGGGGGCAGCAGGCTGTGACCCAGGTGGGTGTGGACGGGGCAGCCCAGCGCCCGGGCCCCGCCGCTGCCTCTGTGCCCCCAGGTCCTGC
AGCGCCCTTCCCGCTGGCTGTGATCCAAAATCCCTTCAGCAATGGTGGCAGTCCGGCGGCCGAGGCTGTCAGCGGGGAGGCACGATTTGC
CTATTTCCCAGCGTCCAGTGTGGGAGATACTACGGCTGTGTCCGTACAGACCACAGACCAGAGCTTGCAGGCTGGAGGCCAGTTCTACGT
CATGATGACGCCCCAGGATGTGCTTCAGACAGGAACACAGAGGACGATCGCCCCCCGGACACACCCTTACTCTCCAAAAATTGATGGAAC
CAGAACACCCCGAGATGAGAGGAGAAGAGCCCAGCACAACGAAGGTGGCCGGACTGTGCCATGCTGCTCCAGACCCAAGGTGGCAGCTCT
CACTGCGGGGACCCTGCTACTTCTGACAGCCATCGGGGCGGCATCCTGGGCCATTGTGGCTGTTCTCCTCAGGAGTGACCAGGAGCCGCT
GTACCCAGTGCAGGTCAGCTCTGCGGACGCTCGGCTCATGGTCTTTGACAAGACGGAAGGGACGTGGCGGCTGCTGTGCTCCTCGCGCTC
CAACGCCAGGGTAGCCGGACTCAGCTGCGAGGAGATGGGCTTCCTCAGGGCACTGACCCACTCCGAGCTGGACGTGCGAACGGCGGGCGC
CAATGGCACGTCGGGCTTCTTCTGTGTGGACGAGGGGAGGCTGCCCCACACCCAGAGGCTGCTGGAGGTCATCTCCGTGTGTGATTGCCC
CAGAGGCCGTTTCTTGGCCGCCATCTGCCAAGACTGTGGCCGCAGGAAGCTGCCCGTGGACCGCATCGTGGGAGGCCGGGACACCAGCTT
GGGCCGGTGGCCGTGGCAAGTCAGCCTTCGCTATGATGGAGCACACCTCTGTGGGGGATCCCTGCTCTCCGGGGACTGGGTGCTGACAGC
CGCCCACTGCTTCCCGGAGCGGAACCGGGTCCTGTCCCGATGGCGAGTGTTTGCCGGTGCCGTGGCCCAGGCCTCTCCCCACGGTCTGCA
GCTGGGGGTGCAGGCTGTGGTCTACCACGGGGGCTATCTTCCCTTTCGGGACCCCAACAGCGAGGAGAACAGCAACGATATTGCCCTGGT
CCACCTCTCCAGTCCCCTGCCCCTCACAGAATACATCCAGCCTGTGTGCCTCCCAGCTGCCGGCCAGGCCCTGGTGGATGGCAAGATCTG
TACCGTGACGGGCTGGGGCAACACGCAGTACTATGGCCAACAGGCCGGGGTACTCCAGGAGGCTCGAGTCCCCATAATCAGCAATGATGT
CTGCAATGGCGCTGACTTCTATGGAAACCAGATCAAGCCCAAGATGTTCTGTGCTGGCTACCCCGAGGGTGGCATTGATGCCTGCCAGGG
CGACAGCGGTGGTCCCTTTGTGTGTGAGGACAGCATCTCTCGGACGCCACGTTGGCGGCTGTGTGGCATTGTGAGTTGGGGCACTGGCTG
TGCCCTGGCCCAGAAGCCAGGCGTCTACACCAAAGTCAGTGACTTCCGGGAGTGGATCTTCCAGGCCATAAAGACTCACTCCGAAGCCAG
CGGCATGGTGACCCAGCTCTGACCGGTGGCTTCTCGCTGCGCAGCCTCCAGGGCCCGAGGTGATCCCGGTGGTGGGATCCACGCTGGGCC
TAGGATGGGACGTTTTTCTTCTTGGGCCCGGTCCACAGGTCCAAGGACACCCTCCCTCCAGGGTCCTCTCTTCCACAGTGGCGGGCCCAC
TCAGCCCCGAGACCACCCAACCTCACCCTCCTGACCCCCATGTAAATATTGTTCTGCTGTCTGGGACTCCTGTCTAGGTGCCCCTGATGA

>97121_97121_10_USF2-HPN_USF2_chr19_35762044_ENST00000595068_HPN_chr19_35540193_ENST00000392226_length(amino acids)=654AA_BP=242
MDMLDPGLDPAASATAAAAASHDKGPEAEEGVELQEGGDGPGAEEQTAVAITSVQQAAFGDHNIQYQFRTETNGGQVTYRVVQVTDGQLD
GQGDTAGAVSVVSTAAFAGGQQAVTQVGVDGAAQRPGPAAASVPPGPAAPFPLAVIQNPFSNGGSPAAEAVSGEARFAYFPASSVGDTTA
VSVQTTDQSLQAGGQFYVMMTPQDVLQTGTQRTIAPRTHPYSPKIDGTRTPRDERRRAQHNEGGRTVPCCSRPKVAALTAGTLLLLTAIG
AASWAIVAVLLRSDQEPLYPVQVSSADARLMVFDKTEGTWRLLCSSRSNARVAGLSCEEMGFLRALTHSELDVRTAGANGTSGFFCVDEG
RLPHTQRLLEVISVCDCPRGRFLAAICQDCGRRKLPVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLS
RWRVFAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYG
QQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKV

--------------------------------------------------------------

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Fusion Gene PPI Analysis for USF2-HPN


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for USF2-HPN


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for USF2-HPN


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource