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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:BIRC3-MALT1 (FusionGDB2 ID:9744)

Fusion Gene Summary for BIRC3-MALT1

check button Fusion gene summary
Fusion gene informationFusion gene name: BIRC3-MALT1
Fusion gene ID: 9744
HgeneTgene
Gene symbol

BIRC3

MALT1

Gene ID

330

10892

Gene namebaculoviral IAP repeat containing 3MALT1 paracaspase
SynonymsAIP1|API2|CIAP2|HAIP1|HIAP1|IAP-1|MALT2|MIHC|RNF49|c-IAP2IMD12|MLT|MLT1|PCASP1
Cytomap

11q22.2

18q21.32

Type of geneprotein-codingprotein-coding
Descriptionbaculoviral IAP repeat-containing protein 3IAP homolog CRING finger protein 49RING-type E3 ubiquitin transferase BIRC3TNFR2-TRAF signaling complex proteinTNFR2-TRAF-signaling complex protein 1apoptosis inhibitor 2cellular inhibitor of apoptosis 2imucosa-associated lymphoid tissue lymphoma translocation protein 1MALT1 proteasecaspase-like proteinmucosa associated lymphoid tissue lymphoma translocation gene 1paracaspase-1
Modification date2020031320200315
UniProtAcc

Q13489

Q9UDY8

Ensembl transtripts involved in fusion geneENST00000263464, ENST00000532808, 
ENST00000526421, 		ENST00000345724, 
ENST00000348428, 
Fusion gene scores* DoF score2 X 3 X 3=184 X 6 X 4=96
# samples 36
** MAII scorelog2(3/18*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(6/96*10)=-0.678071905112638
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: BIRC3 [Title/Abstract] AND MALT1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointBIRC3(102201973)-MALT1(56363598), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneBIRC3

GO:0031398

positive regulation of protein ubiquitination

21931591

TgeneMALT1

GO:0006508

proteolysis

18223652

TgeneMALT1

GO:0042981

regulation of apoptotic process

12819136

TgeneMALT1

GO:0050852

T cell receptor signaling pathway

15125833

TgeneMALT1

GO:0051168

nuclear export

16123224


check buttonFusion gene breakpoints across BIRC3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across MALT1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerKB3..BIRC3chr11

102201972

+MALT1chr18

56363597

+
ChimerKB4..BIRC3chr11

102201972

+MALT1chr18

56363597

ChimerKB4..BIRC3chr11

102201972

+MALT1chr18

56363597

+
ChiTaRS5.0N/AAF123094BIRC3chr11

102201973

+MALT1chr18

56363598

+
ChiTaRS5.0N/AAX055871BIRC3chr11

102201973

+MALT1chr18

56363598

+


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Fusion Gene ORF analysis for BIRC3-MALT1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000263464ENST00000345724BIRC3chr11

102201972

+MALT1chr18

56363597

+
In-frameENST00000263464ENST00000345724BIRC3chr11

102201973

+MALT1chr18

56363598

+
In-frameENST00000263464ENST00000348428BIRC3chr11

102201972

+MALT1chr18

56363597

+
In-frameENST00000263464ENST00000348428BIRC3chr11

102201973

+MALT1chr18

56363598

+
In-frameENST00000532808ENST00000345724BIRC3chr11

102201972

+MALT1chr18

56363597

+
In-frameENST00000532808ENST00000345724BIRC3chr11

102201973

+MALT1chr18

56363598

+
In-frameENST00000532808ENST00000348428BIRC3chr11

102201972

+MALT1chr18

56363597

+
In-frameENST00000532808ENST00000348428BIRC3chr11

102201973

+MALT1chr18

56363598

+
intron-3CDSENST00000526421ENST00000345724BIRC3chr11

102201972

+MALT1chr18

56363597

+
intron-3CDSENST00000526421ENST00000345724BIRC3chr11

102201973

+MALT1chr18

56363598

+
intron-3CDSENST00000526421ENST00000348428BIRC3chr11

102201972

+MALT1chr18

56363597

+
intron-3CDSENST00000526421ENST00000348428BIRC3chr11

102201973

+MALT1chr18

56363598

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000263464BIRC3chr11102201972+ENST00000348428MALT1chr1856363597+84704074275061721140
ENST00000263464BIRC3chr11102201972+ENST00000345724MALT1chr1856363597+64524074275061391129
ENST00000532808BIRC3chr11102201972+ENST00000348428MALT1chr1856363597+5842144612235441140
ENST00000532808BIRC3chr11102201972+ENST00000345724MALT1chr1856363597+3824144612235111129
ENST00000263464BIRC3chr11102201973+ENST00000348428MALT1chr1856363598+84704074275061721140
ENST00000263464BIRC3chr11102201973+ENST00000345724MALT1chr1856363598+64524074275061391129
ENST00000532808BIRC3chr11102201973+ENST00000348428MALT1chr1856363598+5842144612235441140
ENST00000532808BIRC3chr11102201973+ENST00000345724MALT1chr1856363598+3824144612235111129

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000263464ENST00000348428BIRC3chr11102201973+MALT1chr1856363598+0.0027808490.9972192
ENST00000263464ENST00000345724BIRC3chr11102201973+MALT1chr1856363598+0.0046677160.9953323
ENST00000532808ENST00000348428BIRC3chr11102201973+MALT1chr1856363598+0.0002023080.99979776
ENST00000532808ENST00000345724BIRC3chr11102201973+MALT1chr1856363598+0.0003548440.9996451

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Fusion Genomic Features for BIRC3-MALT1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
BIRC3chr11102201972+MALT1chr1856363597+0.0002357190.99976426
BIRC3chr11102201972+MALT1chr1856363597+0.0002357190.99976426

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for BIRC3-MALT1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr11:102201973/chr18:56363598)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
BIRC3

Q13489

MALT1

Q9UDY8

FUNCTION: Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling and cell proliferation, as well as cell invasion and metastasis. Acts as an E3 ubiquitin-protein ligase regulating NF-kappa-B signaling and regulates both canonical and non-canonical NF-kappa-B signaling by acting in opposite directions: acts as a positive regulator of the canonical pathway and suppresses constitutive activation of non-canonical NF-kappa-B signaling. The target proteins for its E3 ubiquitin-protein ligase activity include: RIPK1, RIPK2, RIPK3, RIPK4, CASP3, CASP7, CASP8, IKBKE, TRAF1, and BCL10. Acts as an important regulator of innate immune signaling via regulation of Toll-like receptors (TLRs), Nodlike receptors (NLRs) and RIG-I like receptors (RLRs), collectively referred to as pattern recognition receptors (PRRs). Protects cells from spontaneous formation of the ripoptosome, a large multi-protein complex that has the capability to kill cancer cells in a caspase-dependent and caspase-independent manner. Suppresses ripoptosome formation by ubiquitinating RIPK1 and CASP8. {ECO:0000269|PubMed:21931591, ECO:0000269|PubMed:23453969}.FUNCTION: Protease that enhances BCL10-induced activation: acts via formation of CBM complexes that channel adaptive and innate immune signaling downstream of CARD domain-containing proteins (CARD9, CARD11 and CARD14) to activate NF-kappa-B and MAP kinase p38 pathways which stimulate expression of genes encoding pro-inflammatory cytokines and chemokines (PubMed:11262391, PubMed:18264101, PubMed:24074955). Mediates BCL10 cleavage: MALT1-dependent BCL10 cleavage plays an important role in T-cell antigen receptor-induced integrin adhesion (PubMed:11262391, PubMed:18264101). Involved in the induction of T helper 17 cells (Th17) differentiation (PubMed:11262391, PubMed:18264101). Cleaves RC3H1 and ZC3H12A in response to T-cell receptor (TCR) stimulation which releases their cooperatively repressed targets to promote Th17 cell differentiation (By similarity). Also mediates cleavage of N4BP1 in T-cells following TCR-mediated activation, leading to N4BP1 inactivation (PubMed:31133753). May also have ubiquitin ligase activity: binds to TRAF6, inducing TRAF6 oligomerization and activation of its ligase activity (PubMed:14695475). {ECO:0000250|UniProtKB:Q2TBA3, ECO:0000269|PubMed:11262391, ECO:0000269|PubMed:14695475, ECO:0000269|PubMed:18264101, ECO:0000269|PubMed:24074955, ECO:0000269|PubMed:31133753}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneBIRC3chr11:102201973chr18:56363598ENST00000263464+69169_235441605.0RepeatNote=BIR 2
HgeneBIRC3chr11:102201973chr18:56363598ENST00000263464+69255_322441605.0RepeatNote=BIR 3
HgeneBIRC3chr11:102201973chr18:56363598ENST00000263464+6929_96441605.0RepeatNote=BIR 1
HgeneBIRC3chr11:102201973chr18:56363598ENST00000532808+710169_235441605.0RepeatNote=BIR 2
HgeneBIRC3chr11:102201973chr18:56363598ENST00000532808+710255_322441605.0RepeatNote=BIR 3
HgeneBIRC3chr11:102201973chr18:56363598ENST00000532808+71029_96441605.0RepeatNote=BIR 1
TgeneMALT1chr11:102201973chr18:56363598ENST00000345724116125_201125814.0DomainNote=Ig-like C2-type 1
TgeneMALT1chr11:102201973chr18:56363598ENST00000345724116212_305125814.0DomainNote=Ig-like C2-type 2
TgeneMALT1chr11:102201973chr18:56363598ENST00000348428117125_201125825.0DomainNote=Ig-like C2-type 1
TgeneMALT1chr11:102201973chr18:56363598ENST00000348428117212_305125825.0DomainNote=Ig-like C2-type 2
TgeneMALT1chr11:102201973chr18:56363598ENST00000345724116369_376125814.0MotifNote=Nuclear export signal
TgeneMALT1chr11:102201973chr18:56363598ENST00000348428117369_376125825.0MotifNote=Nuclear export signal
TgeneMALT1chr11:102201973chr18:56363598ENST00000345724116348_562125814.0RegionNote=Caspase-like
TgeneMALT1chr11:102201973chr18:56363598ENST00000348428117348_562125825.0RegionNote=Caspase-like

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneBIRC3chr11:102201973chr18:56363598ENST00000263464+69439_529441605.0DomainCARD
HgeneBIRC3chr11:102201973chr18:56363598ENST00000532808+710439_529441605.0DomainCARD
HgeneBIRC3chr11:102201973chr18:56363598ENST00000263464+69557_592441605.0Zinc fingerRING-type
HgeneBIRC3chr11:102201973chr18:56363598ENST00000532808+710557_592441605.0Zinc fingerRING-type
TgeneMALT1chr11:102201973chr18:56363598ENST0000034572411639_126125814.0DomainNote=Death
TgeneMALT1chr11:102201973chr18:56363598ENST0000034842811739_126125825.0DomainNote=Death


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Fusion Gene Sequence for BIRC3-MALT1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>9744_9744_1_BIRC3-MALT1_BIRC3_chr11_102201972_ENST00000263464_MALT1_chr18_56363597_ENST00000345724_length(transcript)=6452nt_BP=4074nt
GGCCAGGCGACAGGTGTCGCTTGAAAAGACTGGGCTTGTCCTTGCTGGTGCATGCGTCGTCGGCCTCTGGGCAGCAGGTTTACAAAGGAG
GAAAACGACTTCTTCTAGATTTTTTTTTCAGTTTCTTCTATAAATCAAAACATCTCAAAATGGAGACCTAAAATCCTTAAAGGGACTTAG
TCTAATCTCGGGAGGTAGTTTTGTGCATGGGTAAACAAATTAAGTATTAACTGGTGTTTTACTATCCAAAGAATGCTAATTTTATAAACA
TGATCGAGTTATATAAGGTATACCATAATGAGTTTGATTTTGAATTTGATTTGTGGAAATAAAGGAAAAGTGATTCTAGCTGGGGCATAT
TGTTAAAGCATTTTTTTCAGAGTTGGCCAGGCAGTCTCCTACTGGCACATTCTCCCATTATGTAGAATAGAAATAGTACCTGTGTTTGGG
AAAGATTTTAAAATGAGTGACAGTTATTTGGAACAAAGAGCTAATAATCAATCCACTGCAAATTAAAGAAACATGCAGATGAAAGTTTTG
ACACATTAAAATACTTCTACAGTGACAAAGAAAAATCAAGAACAAAGCTTTTTGATATGTGCAACAAATTTAGAGGAAGTAAAAAGATAA
ATGTGATGATTGGTCAAGAAATTATCCAGTTATTTACAAGGCCACTGATATTTTAAACGTCCAAAAGTTTGTTTAAATGGGCTGTTACCG
CTGAGAATGATGAGGATGAGAATGATGGTTGAAGGTTACATTTTAGGAAATGAAGAAACTTAGAAAATTAATATAAAGACAGTGATGAAT
ACAAAGAAGATTTTTATAACAATGTGTAAAATTTTTGGCCAGGGAAAGGAATATTGAAGTTAGATACAATTACTTACCTTTGAGGGAAAT
AATTGTTGGTAATGAGATGTGATGTTTCTCCTGCCACCTGGAAACAAAGCATTGAAGTCTGCAGTTGAAAAGCCCAACGTCTGTGAGATC
CAGGAAACCATGCTTGCAAACCACTGGTAAAAAAAAAAAAAAAAAAAAAAAAAAGCCACAGTGACTTGCTTATTGGTCATTGCTAGTATT
ATCGACTCAGAACCTCTTTACTAATGGCTAGTAAATCATAATTGAGAAATTCTGAATTTTGACAAGGTCTCTGCTGTTGAAATGGTAAAT
TTATTATTTTTTTTGTCATGATAAATTCTGGTTCAAGGTATGCTATCCATGAAATAATTTCTGACCAAAACTAAATTGATGCAATTTGAT
TATCCATCTTAGCCTACAGATGGCATCTGGTAACTTTTGACTGTTTTAAAAAATAAATCCACTATCAGAGTAGATTTGATGTTGGCTTCA
GAAACATTTAGAAAAACAAAAGTTCAAAAATGTTTTCAGGAGGTGATAAGTTGAATAACTCTACAATGTTAGTTCTTTGAGGGGGACAAA
AAATTTAAAATCTTTGAAAGGTCTTATTTTACAGCCATATCTAAATTATCTTAAGAAAATTTTTAACAAAGGGAATGAAATATATATCAT
GATTCTGTTTTTCCAAAAGTAACCTGAATATAGCAATGAAGTTCAGTTTTGTTATTGGTAGTTTGGGCAGAGTCTCTTTTTGCAGCACCT
GTTGTCTACCATAATTACAGAGGACATTTCCATGTTCTAGCCAAGTATACTATTAGAATAAAAAAACTTAACATTGAGTTGCTTCAACAG
CATGAAACTGAGTCCAAAAGACCAAATGAACAAACACATTAATCTCTGATTATTTATTTTAAATAGAATATTTAATTGTGTAAGATCTAA
TAGTATCATTATACTTAAGCAATCATATTCCTGATGATCTATGGGAAATAACTATTATTTAATTAATATTGAAACCAGGTTTTAAGATGT
GTTAGCCAGTCCTGTTACTAGTAAATCTCTTTATTTGGAGAGAAATTTTAGATTGTTTTGTTCTCCTTATTAGAAGGATTGTAGAAAGAA
AAAAATGACTAATTGGAGAAAAATTGGGGATATATCATATTTCACTGAATTCAAAATGTCTTCAGTTGTAAATCTTACCATTATTTTACG
TACCTCTAAGAAATAAAAGTGCTTCTAATTAAAATATGATGTCATTAATTATGAAATACTTCTTGATAACAGAAGTTTTAAAATAGCCAT
CTTAGAATCAGTGAAATATGGTAATGTATTATTTTCCTCCTTTGAGTTAGGTCTTGTGCTTTTTTTTCCTGGCCACTAAATTTCACAATT
TCCAAAAAGCAAAATAAACATATTCTGAATATTTTTGCTGTGAAACACTTGACAGCAGAGCTTTCCACCATGAAAAGAAGCTTCATGAGT
CACACATTACATCTTTGGGTTGATTGAATGCCACTGAAACATTCTAGTAGCCTGGAGAAGTTGACCTACCTGTGGAGATGCCTGCCATTA
AATGGCATCCTGATGGCTTAATACACATCACTCTTCTGTGAAGGGTTTTAATTTTCAACACAGCTTACTCTGTAGCATCATGTTTACATT
GTATGTATAAAGATTATACAAAGGTGCAATTGTGTATTTCTTCCTTAAAATGTATCAGTATAGGATTTAGAATCTCCATGTTGAAACTCT
AAATGCATAGAAATAAAAATAATAAAAAATTTTTCATTTTGGCTTTTCAGCCTAGTATTAAAACTGATAAAAGCAAAGCCATGCACAAAA
CTACCTCCCTAGAGAAAGGCTAGTCCCTTTTCTTCCCCATTCATTTCATTATGAACATAGTAGAAAACAGCATATTCTTATCAAATTTGA
TGAAAAGCGCCAACACGTTTGAACTGAAATACGACTTGTCATGTGAACTGTACCGAATGTCTACGTATTCCACTTTTCCTGCTGGGGTTC
CTGTCTCAGAAAGGAGTCTTGCTCGTGCTGGTTTCTATTACACTGGTGTGAATGACAAGGTCAAATGCTTCTGTTGTGGCCTGATGCTGG
ATAACTGGAAAAGAGGAGACAGTCCTACTGAAAAGCATAAAAAGTTGTATCCTAGCTGCAGATTCGTTCAGAGTCTAAATTCCGTTAACA
ACTTGGAAGCTACCTCTCAGCCTACTTTTCCTTCTTCAGTAACAAATTCCACACACTCATTACTTCCGGGTACAGAAAACAGTGGATATT
TCCGTGGCTCTTATTCAAACTCTCCATCAAATCCTGTAAACTCCAGAGCAAATCAAGATTTTTCTGCCTTGATGAGAAGTTCCTACCACT
GTGCAATGAATAACGAAAATGCCAGATTACTTACTTTTCAGACATGGCCATTGACTTTTCTGTCGCCAACAGATCTGGCAAAAGCAGGCT
TTTACTACATAGGACCTGGAGACAGAGTGGCTTGCTTTGCCTGTGGTGGAAAATTGAGCAATTGGGAACCGAAGGATAATGCTATGTCAG
AACACCTGAGACATTTTCCCAAATGCCCATTTATAGAAAATCAGCTTCAAGACACTTCAAGATACACAGTTTCTAATCTGAGCATGCAGA
CACATGCAGCCCGCTTTAAAACATTCTTTAACTGGCCCTCTAGTGTTCTAGTTAATCCTGAGCAGCTTGCAAGTGCGGGTTTTTATTATG
TGGGTAACAGTGATGATGTCAAATGCTTTTGCTGTGATGGTGGACTCAGGTGTTGGGAATCTGGAGATGATCCATGGGTTCAACATGCCA
AGTGGTTTCCAAGGTGTGAGTACTTGATAAGAATTAAAGGACAGGAGTTCATCCGTCAAGTTCAAGCCAGTTACCCTCATCTACTTGAAC
AGCTGCTATCCACATCAGACAGCCCAGGAGATGAAAATGCAGAGTCATCAATTATCCATTTTGAACCTGGAGAAGACCATTCAGAAGATG
CAATCATGATGAATACTCCTGTGATTAATGCTGCCGTGGAAATGGGCTTTAGTAGAAGCCTGGTAAAACAGACAGTTCAGAGAAAAATCC
TAGCAACTGGAGAGAATTATAGACTAGTCAATGATCTTGTGTTAGACTTACTCAATGCAGAAGATGAAATAAGGGAAGAGGAGAGAGAAA
GAGCAACTGAGGAAAAAGAATCAAGAATAAAGATTACTGTAAACCCAGAGTCAAAGGCAGTCTTGGCTGGACAGTTTGTGAAACTGTGTT
GCCGGGCAACTGGACATCCTTTTGTTCAATATCAGTGGTTCAAAATGAATAAAGAGATTCCAAATGGAAATACATCAGAGCTTATTTTTA
ATGCAGTGCATGTAAAAGATGCAGGCTTTTATGTCTGTCGAGTTAATAACAATTTCACCTTTGAATTCAGCCAGTGGTCACAGCTGGATG
TTTGCGACATCCCAGAGAGCTTCCAGAGAAGTGTTGATGGCGTCTCTGAATCCAAGTTGCAAATCTGTGTTGAACCAACTTCCCAAAAGC
TGATGCCAGGCAGCACATTGGTTTTACAGTGTGTTGCTGTTGGAAGCCCTATTCCTCACTACCAGTGGTTCAAAAATGAATTACCATTAA
CACATGAGACCAAAAAGCTATACATGGTGCCTTATGTGGATTTGGAACACCAAGGAACCTACTGGTGTCATGTATATAATGATCGAGACA
GTCAAGATAGCAAGAAGGTAGAAATCATCATAGATGAATTAAATAATCTTGGTCATCCTGATAATAAAGAGCAAACAACTGACCAGCCTT
TGGCGAAGGACAAGGTTGCCCTTTTGATAGGAAATATGAATTACCGGGAGCACCCCAAGCTCAAAGCTCCTTTGGTGGATGTGTACGAAT
TGACTAACTTACTGAGACAGCTGGACTTCAAAGTGGTTTCACTGTTGGATCTTACTGAATATGAGATGCGTAATGCTGTGGATGAGTTTT
TACTCCTTTTAGACAAGGGAGTATATGGGTTATTATATTATGCAGGACATGGTTATGAAAATTTTGGGAACAGCTTCATGGTCCCCGTTG
ATGCTCCAAATCCATATAGGTCTGAAAATTGTCTGTGTGTACAAAATATACTGAAATTGATGCAAGAAAAAGAAACTGGACTTAATGTGT
TCTTATTGGATATGTGTAGGAAAAGAAATGACTACGATGATACCATTCCAATCTTGGATGCACTAAAAGTCACCGCCAATATTGTGTTTG
GATATGCCACGTGTCAAGGAGCAGAAGCTTTTGAAATCCAGCATTCTGGATTGGCAAATGGAATCTTTATGAAATTTTTAAAAGACAGAT
TATTAGAAGATAAGAAAATCACTGTGTTACTGGATGAAGTTGCAGAAGATATGGGTAAGTGTCACCTTACCAAAGGCAAACAGGCTCTAG
AGATTCGAAGTAGTTTATCTGAGAAGAGAGCACTTACTGATCCAATACAGGGAACAGAATATTCTGCTGAATCTCTTGTGCGGAATCTAC
AGTGGGCCAAGGCTCATGAACTTCCAGAAAGTATGTGTCTTAAGTTTGACTGTGGTGTTCAGATTCAATTAGGATTTGCAGCTGAGTTTT
CCAATGTCATGATCATCTATACAAGTATAGTTTACAAACCACCGGAGATAATAATGTGTGATGCCTACGTTACTGATTTTCCACTTGATC
TAGATATTGATCCAAAAGATGCAAATAAAGGCACACCTGAAGAAACTGGCAGCTACTTGGTATCAAAGGATCTTCCCAAGCATTGCCTCT
ATACCAGACTCAGTTCACTGCAAAAATTAAAGGAACATCTAGTCTTCACAGTATGTTTATCATATCAGTACTCAGGATTGGAAGATACTG
TAGAGGACAAGCAGGAAGTGAATGTTGGGAAACCTCTCATTGCTAAATTAGACATGCATCGAGGTTTGGGAAGGAAGACTTGCTTTCAAA
CTTGTCTTATGTCTAATGGTCCTTACCAGAGTTCTGCAGCCACCTCAGGAGGAGCAGGGCATTATCACTCATTGCAAGACCCATTCCATG
GTGTTTACCATTCACATCCTGGTAATCCAAGTAATGTTACACCAGCAGATAGCTGTCATTGCAGCCGGACTCCAGATGCATTTATTTCAA
GTTTCGCTCACCATGCTTCATGTCATTTTAGTAGAAGTAATGTGCCAGTAGAGACAACTGATGAAATACCATTTAGTTTCTCTGACAGGC
TCAGAATTTCTGAAAAATGACCTCCTTGTTTTTGAAAGTTAGCATAATTTTAGATGCCTGTGAAATAGTACTGCACTTACATAAAGTGAG
ACATTGTGAAAAGGCAAATTTGTATATGTAGAGAAAGAATAGTAGTAACTGTTTCATAGCAAACTTCAGGACTTTGAGATGTTGAAATTA
CATTATTTAATTACAGACTTCCTCTTTCTAAGATTTTGTGAATTGGTTGAATAGTTCTATACAAATGAAGTATGGAGGTGTGTATGTTTA

>9744_9744_1_BIRC3-MALT1_BIRC3_chr11_102201972_ENST00000263464_MALT1_chr18_56363597_ENST00000345724_length(amino acids)=1129AA_BP=442
MNIVENSIFLSNLMKSANTFELKYDLSCELYRMSTYSTFPAGVPVSERSLARAGFYYTGVNDKVKCFCCGLMLDNWKRGDSPTEKHKKLY
PSCRFVQSLNSVNNLEATSQPTFPSSVTNSTHSLLPGTENSGYFRGSYSNSPSNPVNSRANQDFSALMRSSYHCAMNNENARLLTFQTWP
LTFLSPTDLAKAGFYYIGPGDRVACFACGGKLSNWEPKDNAMSEHLRHFPKCPFIENQLQDTSRYTVSNLSMQTHAARFKTFFNWPSSVL
VNPEQLASAGFYYVGNSDDVKCFCCDGGLRCWESGDDPWVQHAKWFPRCEYLIRIKGQEFIRQVQASYPHLLEQLLSTSDSPGDENAESS
IIHFEPGEDHSEDAIMMNTPVINAAVEMGFSRSLVKQTVQRKILATGENYRLVNDLVLDLLNAEDEIREEERERATEEKESRIKITVNPE
SKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSELIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSE
SKLQICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHETKKLYMVPYVDLEHQGTYWCHVYNDRDSQDSKKVEIIIDELNNL
GHPDNKEQTTDQPLAKDKVALLIGNMNYREHPKLKAPLVDVYELTNLLRQLDFKVVSLLDLTEYEMRNAVDEFLLLLDKGVYGLLYYAGH
GYENFGNSFMVPVDAPNPYRSENCLCVQNILKLMQEKETGLNVFLLDMCRKRNDYDDTIPILDALKVTANIVFGYATCQGAEAFEIQHSG
LANGIFMKFLKDRLLEDKKITVLLDEVAEDMGKCHLTKGKQALEIRSSLSEKRALTDPIQGTEYSAESLVRNLQWAKAHELPESMCLKFD
CGVQIQLGFAAEFSNVMIIYTSIVYKPPEIIMCDAYVTDFPLDLDIDPKDANKGTPEETGSYLVSKDLPKHCLYTRLSSLQKLKEHLVFT
VCLSYQYSGLEDTVEDKQEVNVGKPLIAKLDMHRGLGRKTCFQTCLMSNGPYQSSAATSGGAGHYHSLQDPFHGVYHSHPGNPSNVTPAD

--------------------------------------------------------------
>9744_9744_2_BIRC3-MALT1_BIRC3_chr11_102201972_ENST00000263464_MALT1_chr18_56363597_ENST00000348428_length(transcript)=8470nt_BP=4074nt
GGCCAGGCGACAGGTGTCGCTTGAAAAGACTGGGCTTGTCCTTGCTGGTGCATGCGTCGTCGGCCTCTGGGCAGCAGGTTTACAAAGGAG
GAAAACGACTTCTTCTAGATTTTTTTTTCAGTTTCTTCTATAAATCAAAACATCTCAAAATGGAGACCTAAAATCCTTAAAGGGACTTAG
TCTAATCTCGGGAGGTAGTTTTGTGCATGGGTAAACAAATTAAGTATTAACTGGTGTTTTACTATCCAAAGAATGCTAATTTTATAAACA
TGATCGAGTTATATAAGGTATACCATAATGAGTTTGATTTTGAATTTGATTTGTGGAAATAAAGGAAAAGTGATTCTAGCTGGGGCATAT
TGTTAAAGCATTTTTTTCAGAGTTGGCCAGGCAGTCTCCTACTGGCACATTCTCCCATTATGTAGAATAGAAATAGTACCTGTGTTTGGG
AAAGATTTTAAAATGAGTGACAGTTATTTGGAACAAAGAGCTAATAATCAATCCACTGCAAATTAAAGAAACATGCAGATGAAAGTTTTG
ACACATTAAAATACTTCTACAGTGACAAAGAAAAATCAAGAACAAAGCTTTTTGATATGTGCAACAAATTTAGAGGAAGTAAAAAGATAA
ATGTGATGATTGGTCAAGAAATTATCCAGTTATTTACAAGGCCACTGATATTTTAAACGTCCAAAAGTTTGTTTAAATGGGCTGTTACCG
CTGAGAATGATGAGGATGAGAATGATGGTTGAAGGTTACATTTTAGGAAATGAAGAAACTTAGAAAATTAATATAAAGACAGTGATGAAT
ACAAAGAAGATTTTTATAACAATGTGTAAAATTTTTGGCCAGGGAAAGGAATATTGAAGTTAGATACAATTACTTACCTTTGAGGGAAAT
AATTGTTGGTAATGAGATGTGATGTTTCTCCTGCCACCTGGAAACAAAGCATTGAAGTCTGCAGTTGAAAAGCCCAACGTCTGTGAGATC
CAGGAAACCATGCTTGCAAACCACTGGTAAAAAAAAAAAAAAAAAAAAAAAAAAGCCACAGTGACTTGCTTATTGGTCATTGCTAGTATT
ATCGACTCAGAACCTCTTTACTAATGGCTAGTAAATCATAATTGAGAAATTCTGAATTTTGACAAGGTCTCTGCTGTTGAAATGGTAAAT
TTATTATTTTTTTTGTCATGATAAATTCTGGTTCAAGGTATGCTATCCATGAAATAATTTCTGACCAAAACTAAATTGATGCAATTTGAT
TATCCATCTTAGCCTACAGATGGCATCTGGTAACTTTTGACTGTTTTAAAAAATAAATCCACTATCAGAGTAGATTTGATGTTGGCTTCA
GAAACATTTAGAAAAACAAAAGTTCAAAAATGTTTTCAGGAGGTGATAAGTTGAATAACTCTACAATGTTAGTTCTTTGAGGGGGACAAA
AAATTTAAAATCTTTGAAAGGTCTTATTTTACAGCCATATCTAAATTATCTTAAGAAAATTTTTAACAAAGGGAATGAAATATATATCAT
GATTCTGTTTTTCCAAAAGTAACCTGAATATAGCAATGAAGTTCAGTTTTGTTATTGGTAGTTTGGGCAGAGTCTCTTTTTGCAGCACCT
GTTGTCTACCATAATTACAGAGGACATTTCCATGTTCTAGCCAAGTATACTATTAGAATAAAAAAACTTAACATTGAGTTGCTTCAACAG
CATGAAACTGAGTCCAAAAGACCAAATGAACAAACACATTAATCTCTGATTATTTATTTTAAATAGAATATTTAATTGTGTAAGATCTAA
TAGTATCATTATACTTAAGCAATCATATTCCTGATGATCTATGGGAAATAACTATTATTTAATTAATATTGAAACCAGGTTTTAAGATGT
GTTAGCCAGTCCTGTTACTAGTAAATCTCTTTATTTGGAGAGAAATTTTAGATTGTTTTGTTCTCCTTATTAGAAGGATTGTAGAAAGAA
AAAAATGACTAATTGGAGAAAAATTGGGGATATATCATATTTCACTGAATTCAAAATGTCTTCAGTTGTAAATCTTACCATTATTTTACG
TACCTCTAAGAAATAAAAGTGCTTCTAATTAAAATATGATGTCATTAATTATGAAATACTTCTTGATAACAGAAGTTTTAAAATAGCCAT
CTTAGAATCAGTGAAATATGGTAATGTATTATTTTCCTCCTTTGAGTTAGGTCTTGTGCTTTTTTTTCCTGGCCACTAAATTTCACAATT
TCCAAAAAGCAAAATAAACATATTCTGAATATTTTTGCTGTGAAACACTTGACAGCAGAGCTTTCCACCATGAAAAGAAGCTTCATGAGT
CACACATTACATCTTTGGGTTGATTGAATGCCACTGAAACATTCTAGTAGCCTGGAGAAGTTGACCTACCTGTGGAGATGCCTGCCATTA
AATGGCATCCTGATGGCTTAATACACATCACTCTTCTGTGAAGGGTTTTAATTTTCAACACAGCTTACTCTGTAGCATCATGTTTACATT
GTATGTATAAAGATTATACAAAGGTGCAATTGTGTATTTCTTCCTTAAAATGTATCAGTATAGGATTTAGAATCTCCATGTTGAAACTCT
AAATGCATAGAAATAAAAATAATAAAAAATTTTTCATTTTGGCTTTTCAGCCTAGTATTAAAACTGATAAAAGCAAAGCCATGCACAAAA
CTACCTCCCTAGAGAAAGGCTAGTCCCTTTTCTTCCCCATTCATTTCATTATGAACATAGTAGAAAACAGCATATTCTTATCAAATTTGA
TGAAAAGCGCCAACACGTTTGAACTGAAATACGACTTGTCATGTGAACTGTACCGAATGTCTACGTATTCCACTTTTCCTGCTGGGGTTC
CTGTCTCAGAAAGGAGTCTTGCTCGTGCTGGTTTCTATTACACTGGTGTGAATGACAAGGTCAAATGCTTCTGTTGTGGCCTGATGCTGG
ATAACTGGAAAAGAGGAGACAGTCCTACTGAAAAGCATAAAAAGTTGTATCCTAGCTGCAGATTCGTTCAGAGTCTAAATTCCGTTAACA
ACTTGGAAGCTACCTCTCAGCCTACTTTTCCTTCTTCAGTAACAAATTCCACACACTCATTACTTCCGGGTACAGAAAACAGTGGATATT
TCCGTGGCTCTTATTCAAACTCTCCATCAAATCCTGTAAACTCCAGAGCAAATCAAGATTTTTCTGCCTTGATGAGAAGTTCCTACCACT
GTGCAATGAATAACGAAAATGCCAGATTACTTACTTTTCAGACATGGCCATTGACTTTTCTGTCGCCAACAGATCTGGCAAAAGCAGGCT
TTTACTACATAGGACCTGGAGACAGAGTGGCTTGCTTTGCCTGTGGTGGAAAATTGAGCAATTGGGAACCGAAGGATAATGCTATGTCAG
AACACCTGAGACATTTTCCCAAATGCCCATTTATAGAAAATCAGCTTCAAGACACTTCAAGATACACAGTTTCTAATCTGAGCATGCAGA
CACATGCAGCCCGCTTTAAAACATTCTTTAACTGGCCCTCTAGTGTTCTAGTTAATCCTGAGCAGCTTGCAAGTGCGGGTTTTTATTATG
TGGGTAACAGTGATGATGTCAAATGCTTTTGCTGTGATGGTGGACTCAGGTGTTGGGAATCTGGAGATGATCCATGGGTTCAACATGCCA
AGTGGTTTCCAAGGTGTGAGTACTTGATAAGAATTAAAGGACAGGAGTTCATCCGTCAAGTTCAAGCCAGTTACCCTCATCTACTTGAAC
AGCTGCTATCCACATCAGACAGCCCAGGAGATGAAAATGCAGAGTCATCAATTATCCATTTTGAACCTGGAGAAGACCATTCAGAAGATG
CAATCATGATGAATACTCCTGTGATTAATGCTGCCGTGGAAATGGGCTTTAGTAGAAGCCTGGTAAAACAGACAGTTCAGAGAAAAATCC
TAGCAACTGGAGAGAATTATAGACTAGTCAATGATCTTGTGTTAGACTTACTCAATGCAGAAGATGAAATAAGGGAAGAGGAGAGAGAAA
GAGCAACTGAGGAAAAAGAATCAAGAATAAAGATTACTGTAAACCCAGAGTCAAAGGCAGTCTTGGCTGGACAGTTTGTGAAACTGTGTT
GCCGGGCAACTGGACATCCTTTTGTTCAATATCAGTGGTTCAAAATGAATAAAGAGATTCCAAATGGAAATACATCAGAGCTTATTTTTA
ATGCAGTGCATGTAAAAGATGCAGGCTTTTATGTCTGTCGAGTTAATAACAATTTCACCTTTGAATTCAGCCAGTGGTCACAGCTGGATG
TTTGCGACATCCCAGAGAGCTTCCAGAGAAGTGTTGATGGCGTCTCTGAATCCAAGTTGCAAATCTGTGTTGAACCAACTTCCCAAAAGC
TGATGCCAGGCAGCACATTGGTTTTACAGTGTGTTGCTGTTGGAAGCCCTATTCCTCACTACCAGTGGTTCAAAAATGAATTACCATTAA
CACATGAGACCAAAAAGCTATACATGGTGCCTTATGTGGATTTGGAACACCAAGGAACCTACTGGTGTCATGTATATAATGATCGAGACA
GTCAAGATAGCAAGAAGGTAGAAATCATCATAGGAAGAACAGATGAGGCAGTGGAGTGCACTGAAGATGAATTAAATAATCTTGGTCATC
CTGATAATAAAGAGCAAACAACTGACCAGCCTTTGGCGAAGGACAAGGTTGCCCTTTTGATAGGAAATATGAATTACCGGGAGCACCCCA
AGCTCAAAGCTCCTTTGGTGGATGTGTACGAATTGACTAACTTACTGAGACAGCTGGACTTCAAAGTGGTTTCACTGTTGGATCTTACTG
AATATGAGATGCGTAATGCTGTGGATGAGTTTTTACTCCTTTTAGACAAGGGAGTATATGGGTTATTATATTATGCAGGACATGGTTATG
AAAATTTTGGGAACAGCTTCATGGTCCCCGTTGATGCTCCAAATCCATATAGGTCTGAAAATTGTCTGTGTGTACAAAATATACTGAAAT
TGATGCAAGAAAAAGAAACTGGACTTAATGTGTTCTTATTGGATATGTGTAGGAAAAGAAATGACTACGATGATACCATTCCAATCTTGG
ATGCACTAAAAGTCACCGCCAATATTGTGTTTGGATATGCCACGTGTCAAGGAGCAGAAGCTTTTGAAATCCAGCATTCTGGATTGGCAA
ATGGAATCTTTATGAAATTTTTAAAAGACAGATTATTAGAAGATAAGAAAATCACTGTGTTACTGGATGAAGTTGCAGAAGATATGGGTA
AGTGTCACCTTACCAAAGGCAAACAGGCTCTAGAGATTCGAAGTAGTTTATCTGAGAAGAGAGCACTTACTGATCCAATACAGGGAACAG
AATATTCTGCTGAATCTCTTGTGCGGAATCTACAGTGGGCCAAGGCTCATGAACTTCCAGAAAGTATGTGTCTTAAGTTTGACTGTGGTG
TTCAGATTCAATTAGGATTTGCAGCTGAGTTTTCCAATGTCATGATCATCTATACAAGTATAGTTTACAAACCACCGGAGATAATAATGT
GTGATGCCTACGTTACTGATTTTCCACTTGATCTAGATATTGATCCAAAAGATGCAAATAAAGGCACACCTGAAGAAACTGGCAGCTACT
TGGTATCAAAGGATCTTCCCAAGCATTGCCTCTATACCAGACTCAGTTCACTGCAAAAATTAAAGGAACATCTAGTCTTCACAGTATGTT
TATCATATCAGTACTCAGGATTGGAAGATACTGTAGAGGACAAGCAGGAAGTGAATGTTGGGAAACCTCTCATTGCTAAATTAGACATGC
ATCGAGGTTTGGGAAGGAAGACTTGCTTTCAAACTTGTCTTATGTCTAATGGTCCTTACCAGAGTTCTGCAGCCACCTCAGGAGGAGCAG
GGCATTATCACTCATTGCAAGACCCATTCCATGGTGTTTACCATTCACATCCTGGTAATCCAAGTAATGTTACACCAGCAGATAGCTGTC
ATTGCAGCCGGACTCCAGATGCATTTATTTCAAGTTTCGCTCACCATGCTTCATGTCATTTTAGTAGAAGTAATGTGCCAGTAGAGACAA
CTGATGAAATACCATTTAGTTTCTCTGACAGGCTCAGAATTTCTGAAAAATGACCTCCTTGTTTTTGAAAGTTAGCATAATTTTAGATGC
CTGTGAAATAGTACTGCACTTACATAAAGTGAGACATTGTGAAAAGGCAAATTTGTATATGTAGAGAAAGAATAGTAGTAACTGTTTCAT
AGCAAACTTCAGGACTTTGAGATGTTGAAATTACATTATTTAATTACAGACTTCCTCTTTCTAAGATTTTGTGAATTGGTTGAATAGTTC
TATACAAATGAAGTATGGAGGTGTGTATGTTTATATGTATATAACAAAATATTTTCATTGTGACCACTCTGAAGTAAGAGCAATGGGAAT
GGCATTATTGTAGAATAAGTCATTGTATTTTTAACACCAGAAAGAACCTTGCCGATCACCAGGCATAACCTAATTTTATCCATGGAAGAA
ACACAGAAAGGCATCTAAGTTAGAGCTGGCACCAGAACTGAGACCTCCAGAAATCTATTCCAGTATTTTTTCCACTACACAACTGCCTTC
CTGACAGGTTCTGAGATAAGTGTTATGTTTGTAGATAGAGTGAAATATATTTATATATATATAAATATATACAGATACATATCTGTGTAT
TATCTCAAGGAATGTACAAACTTTAGTTTTTGATTATAAGGACTTCACTGCAAGTTTTAGTTAAGAGGTTTGTATATAAATCTGTTATAG
AACAGGCTGAAATTTCTTGTTCATAAGATTATGAAACCACATGAGAAGTGATAAAATGTTTGTTAAAGCTAGATAGAGGTTAAGAATCAA
GATATAATGGATAATTTTCATAGCTGCCTATCAGAATTTCCCAAATATTTAGCATCTTCCTTGATAATATGTATTTTCTTCTTGAATTTC
ACTGGCCTAATGAGATAATACTCTTATCTTTGGCTCTACCTAAAAGTTGGTTAAAAATGCAATTGGCATTAACAAGGAAAAATACTGAAT
TAGTAATTTTAAAAGTCTCACAAAGAAAATCCCAGGCCTAGATGGCTGCATTGTTGAATTCTGCCAAACATTAAAATTAGCACTAATTTT
TTGCACACTGTTTCTAAAAGTAGGAGAGGAAAGAACACTTCCCAACTTACTCTAGGTCAGTATTACCCTGATACTAGACTAGACATCACA
AGAAAACTATAAGCCAATATTCCTTATTAATACAAACACAAAAATCATTAACAAAAATATTAGCAAACTGAATCCAGCAACCTATAAAAA
GGATTCTATATCATGACCAAGTGGAATTTATCCCAGGAATTCAAGGTTGGTTCAACATCTAAAAATCAAATAAGCTAATATACAGTCAGT
TCTCATTATTCACAGTAATTATGTTCTACAGAATATTCTCCCATAAACACTGAATTAAATATGGAACAACTGCTTTTAGGAGAAAGTGTA
TTTGTGTATATGTGTGTATACATATGTTTATCTCACACACATTATGAGCTTGAATTCTTAATTCATCCTAGCAAATTCTACCTTATTTTA
CAGAAGTGAAAGTGAGGTATCAGAAGTGTTAAGTGACATGCCTGAGGCACCCCCCTAACAGGTGTCAGAGCTGAAATTCAAACCCCATCC
AGCTGGCCCCGGAGCCAGAGCTTCTTGTACTACACAGAATTGCCCCTGCCATTTCCACCCTCCAGTCATTTCTCTATGAGACTGAAGCAG
GAAGGCAGAGCATCATCTTGTTCAGCCTCAGCTGGGAACATGTGTACTGGGTGACTCAAATTTTTCACCCATTTACACATATCCACAAAT
GACTGCAAAAGTGCCACGGATATCAATTTGAGGGTTATAAATTTTAGCAAGTTGGTAAATTCACAAATACATAACCTTGAATAATGAGGA
TCAACTGTACCATATTTAATAAAGCACAAAACCCACACAGATTGTCTTATTACAGCATTTGATAAAATCCAAAACTCTTTCATAAAAACA
CTCAACAAACTTAGGAATAAAAGGAATCTTCCTAGATATGATAAATATAACATCTATGAAAAGCCCACACCTAACATTATACTTCATGGT
GATAGACTGAAGGCTGAATGTTTTCCCCTTAAGATTGGGAAGAAGGACAAGGATGTTCACTCGGCACTACTTCTATTCAGCATTGTACTT
GAAGTTCTAGCCACAGCAGTTAGGTTAGGAATTCAAGGTTTGTTCAACATCTAAAAATCAAATAAGCTAATAAAGAAAAGAGGTTTATAC
TGCAAAAGAAGTGAAACTATATGTATTCACAGTTGATACATAGTTGTATATAGAAAATGCTAAAGAATCCATAAAAAGTAATAAATGAGT

>9744_9744_2_BIRC3-MALT1_BIRC3_chr11_102201972_ENST00000263464_MALT1_chr18_56363597_ENST00000348428_length(amino acids)=1140AA_BP=442
MNIVENSIFLSNLMKSANTFELKYDLSCELYRMSTYSTFPAGVPVSERSLARAGFYYTGVNDKVKCFCCGLMLDNWKRGDSPTEKHKKLY
PSCRFVQSLNSVNNLEATSQPTFPSSVTNSTHSLLPGTENSGYFRGSYSNSPSNPVNSRANQDFSALMRSSYHCAMNNENARLLTFQTWP
LTFLSPTDLAKAGFYYIGPGDRVACFACGGKLSNWEPKDNAMSEHLRHFPKCPFIENQLQDTSRYTVSNLSMQTHAARFKTFFNWPSSVL
VNPEQLASAGFYYVGNSDDVKCFCCDGGLRCWESGDDPWVQHAKWFPRCEYLIRIKGQEFIRQVQASYPHLLEQLLSTSDSPGDENAESS
IIHFEPGEDHSEDAIMMNTPVINAAVEMGFSRSLVKQTVQRKILATGENYRLVNDLVLDLLNAEDEIREEERERATEEKESRIKITVNPE
SKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSELIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSE
SKLQICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHETKKLYMVPYVDLEHQGTYWCHVYNDRDSQDSKKVEIIIGRTDEA
VECTEDELNNLGHPDNKEQTTDQPLAKDKVALLIGNMNYREHPKLKAPLVDVYELTNLLRQLDFKVVSLLDLTEYEMRNAVDEFLLLLDK
GVYGLLYYAGHGYENFGNSFMVPVDAPNPYRSENCLCVQNILKLMQEKETGLNVFLLDMCRKRNDYDDTIPILDALKVTANIVFGYATCQ
GAEAFEIQHSGLANGIFMKFLKDRLLEDKKITVLLDEVAEDMGKCHLTKGKQALEIRSSLSEKRALTDPIQGTEYSAESLVRNLQWAKAH
ELPESMCLKFDCGVQIQLGFAAEFSNVMIIYTSIVYKPPEIIMCDAYVTDFPLDLDIDPKDANKGTPEETGSYLVSKDLPKHCLYTRLSS
LQKLKEHLVFTVCLSYQYSGLEDTVEDKQEVNVGKPLIAKLDMHRGLGRKTCFQTCLMSNGPYQSSAATSGGAGHYHSLQDPFHGVYHSH

--------------------------------------------------------------
>9744_9744_3_BIRC3-MALT1_BIRC3_chr11_102201972_ENST00000532808_MALT1_chr18_56363597_ENST00000345724_length(transcript)=3824nt_BP=1446nt
GGGCAGCAGGTTTACAAAGGAGGAAAACGACTTCTTCTAGATTTTTTTTTCAGTTTCTTCTATAAATCAAAACTACCTCCCTAGAGAAAG
GCTAGTCCCTTTTCTTCCCCATTCATTTCATTATGAACATAGTAGAAAACAGCATATTCTTATCAAATTTGATGAAAAGCGCCAACACGT
TTGAACTGAAATACGACTTGTCATGTGAACTGTACCGAATGTCTACGTATTCCACTTTTCCTGCTGGGGTTCCTGTCTCAGAAAGGAGTC
TTGCTCGTGCTGGTTTCTATTACACTGGTGTGAATGACAAGGTCAAATGCTTCTGTTGTGGCCTGATGCTGGATAACTGGAAAAGAGGAG
ACAGTCCTACTGAAAAGCATAAAAAGTTGTATCCTAGCTGCAGATTCGTTCAGAGTCTAAATTCCGTTAACAACTTGGAAGCTACCTCTC
AGCCTACTTTTCCTTCTTCAGTAACAAATTCCACACACTCATTACTTCCGGGTACAGAAAACAGTGGATATTTCCGTGGCTCTTATTCAA
ACTCTCCATCAAATCCTGTAAACTCCAGAGCAAATCAAGATTTTTCTGCCTTGATGAGAAGTTCCTACCACTGTGCAATGAATAACGAAA
ATGCCAGATTACTTACTTTTCAGACATGGCCATTGACTTTTCTGTCGCCAACAGATCTGGCAAAAGCAGGCTTTTACTACATAGGACCTG
GAGACAGAGTGGCTTGCTTTGCCTGTGGTGGAAAATTGAGCAATTGGGAACCGAAGGATAATGCTATGTCAGAACACCTGAGACATTTTC
CCAAATGCCCATTTATAGAAAATCAGCTTCAAGACACTTCAAGATACACAGTTTCTAATCTGAGCATGCAGACACATGCAGCCCGCTTTA
AAACATTCTTTAACTGGCCCTCTAGTGTTCTAGTTAATCCTGAGCAGCTTGCAAGTGCGGGTTTTTATTATGTGGGTAACAGTGATGATG
TCAAATGCTTTTGCTGTGATGGTGGACTCAGGTGTTGGGAATCTGGAGATGATCCATGGGTTCAACATGCCAAGTGGTTTCCAAGGTGTG
AGTACTTGATAAGAATTAAAGGACAGGAGTTCATCCGTCAAGTTCAAGCCAGTTACCCTCATCTACTTGAACAGCTGCTATCCACATCAG
ACAGCCCAGGAGATGAAAATGCAGAGTCATCAATTATCCATTTTGAACCTGGAGAAGACCATTCAGAAGATGCAATCATGATGAATACTC
CTGTGATTAATGCTGCCGTGGAAATGGGCTTTAGTAGAAGCCTGGTAAAACAGACAGTTCAGAGAAAAATCCTAGCAACTGGAGAGAATT
ATAGACTAGTCAATGATCTTGTGTTAGACTTACTCAATGCAGAAGATGAAATAAGGGAAGAGGAGAGAGAAAGAGCAACTGAGGAAAAAG
AATCAAGAATAAAGATTACTGTAAACCCAGAGTCAAAGGCAGTCTTGGCTGGACAGTTTGTGAAACTGTGTTGCCGGGCAACTGGACATC
CTTTTGTTCAATATCAGTGGTTCAAAATGAATAAAGAGATTCCAAATGGAAATACATCAGAGCTTATTTTTAATGCAGTGCATGTAAAAG
ATGCAGGCTTTTATGTCTGTCGAGTTAATAACAATTTCACCTTTGAATTCAGCCAGTGGTCACAGCTGGATGTTTGCGACATCCCAGAGA
GCTTCCAGAGAAGTGTTGATGGCGTCTCTGAATCCAAGTTGCAAATCTGTGTTGAACCAACTTCCCAAAAGCTGATGCCAGGCAGCACAT
TGGTTTTACAGTGTGTTGCTGTTGGAAGCCCTATTCCTCACTACCAGTGGTTCAAAAATGAATTACCATTAACACATGAGACCAAAAAGC
TATACATGGTGCCTTATGTGGATTTGGAACACCAAGGAACCTACTGGTGTCATGTATATAATGATCGAGACAGTCAAGATAGCAAGAAGG
TAGAAATCATCATAGATGAATTAAATAATCTTGGTCATCCTGATAATAAAGAGCAAACAACTGACCAGCCTTTGGCGAAGGACAAGGTTG
CCCTTTTGATAGGAAATATGAATTACCGGGAGCACCCCAAGCTCAAAGCTCCTTTGGTGGATGTGTACGAATTGACTAACTTACTGAGAC
AGCTGGACTTCAAAGTGGTTTCACTGTTGGATCTTACTGAATATGAGATGCGTAATGCTGTGGATGAGTTTTTACTCCTTTTAGACAAGG
GAGTATATGGGTTATTATATTATGCAGGACATGGTTATGAAAATTTTGGGAACAGCTTCATGGTCCCCGTTGATGCTCCAAATCCATATA
GGTCTGAAAATTGTCTGTGTGTACAAAATATACTGAAATTGATGCAAGAAAAAGAAACTGGACTTAATGTGTTCTTATTGGATATGTGTA
GGAAAAGAAATGACTACGATGATACCATTCCAATCTTGGATGCACTAAAAGTCACCGCCAATATTGTGTTTGGATATGCCACGTGTCAAG
GAGCAGAAGCTTTTGAAATCCAGCATTCTGGATTGGCAAATGGAATCTTTATGAAATTTTTAAAAGACAGATTATTAGAAGATAAGAAAA
TCACTGTGTTACTGGATGAAGTTGCAGAAGATATGGGTAAGTGTCACCTTACCAAAGGCAAACAGGCTCTAGAGATTCGAAGTAGTTTAT
CTGAGAAGAGAGCACTTACTGATCCAATACAGGGAACAGAATATTCTGCTGAATCTCTTGTGCGGAATCTACAGTGGGCCAAGGCTCATG
AACTTCCAGAAAGTATGTGTCTTAAGTTTGACTGTGGTGTTCAGATTCAATTAGGATTTGCAGCTGAGTTTTCCAATGTCATGATCATCT
ATACAAGTATAGTTTACAAACCACCGGAGATAATAATGTGTGATGCCTACGTTACTGATTTTCCACTTGATCTAGATATTGATCCAAAAG
ATGCAAATAAAGGCACACCTGAAGAAACTGGCAGCTACTTGGTATCAAAGGATCTTCCCAAGCATTGCCTCTATACCAGACTCAGTTCAC
TGCAAAAATTAAAGGAACATCTAGTCTTCACAGTATGTTTATCATATCAGTACTCAGGATTGGAAGATACTGTAGAGGACAAGCAGGAAG
TGAATGTTGGGAAACCTCTCATTGCTAAATTAGACATGCATCGAGGTTTGGGAAGGAAGACTTGCTTTCAAACTTGTCTTATGTCTAATG
GTCCTTACCAGAGTTCTGCAGCCACCTCAGGAGGAGCAGGGCATTATCACTCATTGCAAGACCCATTCCATGGTGTTTACCATTCACATC
CTGGTAATCCAAGTAATGTTACACCAGCAGATAGCTGTCATTGCAGCCGGACTCCAGATGCATTTATTTCAAGTTTCGCTCACCATGCTT
CATGTCATTTTAGTAGAAGTAATGTGCCAGTAGAGACAACTGATGAAATACCATTTAGTTTCTCTGACAGGCTCAGAATTTCTGAAAAAT
GACCTCCTTGTTTTTGAAAGTTAGCATAATTTTAGATGCCTGTGAAATAGTACTGCACTTACATAAAGTGAGACATTGTGAAAAGGCAAA
TTTGTATATGTAGAGAAAGAATAGTAGTAACTGTTTCATAGCAAACTTCAGGACTTTGAGATGTTGAAATTACATTATTTAATTACAGAC
TTCCTCTTTCTAAGATTTTGTGAATTGGTTGAATAGTTCTATACAAATGAAGTATGGAGGTGTGTATGTTTATATGTATATAACAAAATA

>9744_9744_3_BIRC3-MALT1_BIRC3_chr11_102201972_ENST00000532808_MALT1_chr18_56363597_ENST00000345724_length(amino acids)=1129AA_BP=442
MNIVENSIFLSNLMKSANTFELKYDLSCELYRMSTYSTFPAGVPVSERSLARAGFYYTGVNDKVKCFCCGLMLDNWKRGDSPTEKHKKLY
PSCRFVQSLNSVNNLEATSQPTFPSSVTNSTHSLLPGTENSGYFRGSYSNSPSNPVNSRANQDFSALMRSSYHCAMNNENARLLTFQTWP
LTFLSPTDLAKAGFYYIGPGDRVACFACGGKLSNWEPKDNAMSEHLRHFPKCPFIENQLQDTSRYTVSNLSMQTHAARFKTFFNWPSSVL
VNPEQLASAGFYYVGNSDDVKCFCCDGGLRCWESGDDPWVQHAKWFPRCEYLIRIKGQEFIRQVQASYPHLLEQLLSTSDSPGDENAESS
IIHFEPGEDHSEDAIMMNTPVINAAVEMGFSRSLVKQTVQRKILATGENYRLVNDLVLDLLNAEDEIREEERERATEEKESRIKITVNPE
SKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSELIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSE
SKLQICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHETKKLYMVPYVDLEHQGTYWCHVYNDRDSQDSKKVEIIIDELNNL
GHPDNKEQTTDQPLAKDKVALLIGNMNYREHPKLKAPLVDVYELTNLLRQLDFKVVSLLDLTEYEMRNAVDEFLLLLDKGVYGLLYYAGH
GYENFGNSFMVPVDAPNPYRSENCLCVQNILKLMQEKETGLNVFLLDMCRKRNDYDDTIPILDALKVTANIVFGYATCQGAEAFEIQHSG
LANGIFMKFLKDRLLEDKKITVLLDEVAEDMGKCHLTKGKQALEIRSSLSEKRALTDPIQGTEYSAESLVRNLQWAKAHELPESMCLKFD
CGVQIQLGFAAEFSNVMIIYTSIVYKPPEIIMCDAYVTDFPLDLDIDPKDANKGTPEETGSYLVSKDLPKHCLYTRLSSLQKLKEHLVFT
VCLSYQYSGLEDTVEDKQEVNVGKPLIAKLDMHRGLGRKTCFQTCLMSNGPYQSSAATSGGAGHYHSLQDPFHGVYHSHPGNPSNVTPAD

--------------------------------------------------------------
>9744_9744_4_BIRC3-MALT1_BIRC3_chr11_102201972_ENST00000532808_MALT1_chr18_56363597_ENST00000348428_length(transcript)=5842nt_BP=1446nt
GGGCAGCAGGTTTACAAAGGAGGAAAACGACTTCTTCTAGATTTTTTTTTCAGTTTCTTCTATAAATCAAAACTACCTCCCTAGAGAAAG
GCTAGTCCCTTTTCTTCCCCATTCATTTCATTATGAACATAGTAGAAAACAGCATATTCTTATCAAATTTGATGAAAAGCGCCAACACGT
TTGAACTGAAATACGACTTGTCATGTGAACTGTACCGAATGTCTACGTATTCCACTTTTCCTGCTGGGGTTCCTGTCTCAGAAAGGAGTC
TTGCTCGTGCTGGTTTCTATTACACTGGTGTGAATGACAAGGTCAAATGCTTCTGTTGTGGCCTGATGCTGGATAACTGGAAAAGAGGAG
ACAGTCCTACTGAAAAGCATAAAAAGTTGTATCCTAGCTGCAGATTCGTTCAGAGTCTAAATTCCGTTAACAACTTGGAAGCTACCTCTC
AGCCTACTTTTCCTTCTTCAGTAACAAATTCCACACACTCATTACTTCCGGGTACAGAAAACAGTGGATATTTCCGTGGCTCTTATTCAA
ACTCTCCATCAAATCCTGTAAACTCCAGAGCAAATCAAGATTTTTCTGCCTTGATGAGAAGTTCCTACCACTGTGCAATGAATAACGAAA
ATGCCAGATTACTTACTTTTCAGACATGGCCATTGACTTTTCTGTCGCCAACAGATCTGGCAAAAGCAGGCTTTTACTACATAGGACCTG
GAGACAGAGTGGCTTGCTTTGCCTGTGGTGGAAAATTGAGCAATTGGGAACCGAAGGATAATGCTATGTCAGAACACCTGAGACATTTTC
CCAAATGCCCATTTATAGAAAATCAGCTTCAAGACACTTCAAGATACACAGTTTCTAATCTGAGCATGCAGACACATGCAGCCCGCTTTA
AAACATTCTTTAACTGGCCCTCTAGTGTTCTAGTTAATCCTGAGCAGCTTGCAAGTGCGGGTTTTTATTATGTGGGTAACAGTGATGATG
TCAAATGCTTTTGCTGTGATGGTGGACTCAGGTGTTGGGAATCTGGAGATGATCCATGGGTTCAACATGCCAAGTGGTTTCCAAGGTGTG
AGTACTTGATAAGAATTAAAGGACAGGAGTTCATCCGTCAAGTTCAAGCCAGTTACCCTCATCTACTTGAACAGCTGCTATCCACATCAG
ACAGCCCAGGAGATGAAAATGCAGAGTCATCAATTATCCATTTTGAACCTGGAGAAGACCATTCAGAAGATGCAATCATGATGAATACTC
CTGTGATTAATGCTGCCGTGGAAATGGGCTTTAGTAGAAGCCTGGTAAAACAGACAGTTCAGAGAAAAATCCTAGCAACTGGAGAGAATT
ATAGACTAGTCAATGATCTTGTGTTAGACTTACTCAATGCAGAAGATGAAATAAGGGAAGAGGAGAGAGAAAGAGCAACTGAGGAAAAAG
AATCAAGAATAAAGATTACTGTAAACCCAGAGTCAAAGGCAGTCTTGGCTGGACAGTTTGTGAAACTGTGTTGCCGGGCAACTGGACATC
CTTTTGTTCAATATCAGTGGTTCAAAATGAATAAAGAGATTCCAAATGGAAATACATCAGAGCTTATTTTTAATGCAGTGCATGTAAAAG
ATGCAGGCTTTTATGTCTGTCGAGTTAATAACAATTTCACCTTTGAATTCAGCCAGTGGTCACAGCTGGATGTTTGCGACATCCCAGAGA
GCTTCCAGAGAAGTGTTGATGGCGTCTCTGAATCCAAGTTGCAAATCTGTGTTGAACCAACTTCCCAAAAGCTGATGCCAGGCAGCACAT
TGGTTTTACAGTGTGTTGCTGTTGGAAGCCCTATTCCTCACTACCAGTGGTTCAAAAATGAATTACCATTAACACATGAGACCAAAAAGC
TATACATGGTGCCTTATGTGGATTTGGAACACCAAGGAACCTACTGGTGTCATGTATATAATGATCGAGACAGTCAAGATAGCAAGAAGG
TAGAAATCATCATAGGAAGAACAGATGAGGCAGTGGAGTGCACTGAAGATGAATTAAATAATCTTGGTCATCCTGATAATAAAGAGCAAA
CAACTGACCAGCCTTTGGCGAAGGACAAGGTTGCCCTTTTGATAGGAAATATGAATTACCGGGAGCACCCCAAGCTCAAAGCTCCTTTGG
TGGATGTGTACGAATTGACTAACTTACTGAGACAGCTGGACTTCAAAGTGGTTTCACTGTTGGATCTTACTGAATATGAGATGCGTAATG
CTGTGGATGAGTTTTTACTCCTTTTAGACAAGGGAGTATATGGGTTATTATATTATGCAGGACATGGTTATGAAAATTTTGGGAACAGCT
TCATGGTCCCCGTTGATGCTCCAAATCCATATAGGTCTGAAAATTGTCTGTGTGTACAAAATATACTGAAATTGATGCAAGAAAAAGAAA
CTGGACTTAATGTGTTCTTATTGGATATGTGTAGGAAAAGAAATGACTACGATGATACCATTCCAATCTTGGATGCACTAAAAGTCACCG
CCAATATTGTGTTTGGATATGCCACGTGTCAAGGAGCAGAAGCTTTTGAAATCCAGCATTCTGGATTGGCAAATGGAATCTTTATGAAAT
TTTTAAAAGACAGATTATTAGAAGATAAGAAAATCACTGTGTTACTGGATGAAGTTGCAGAAGATATGGGTAAGTGTCACCTTACCAAAG
GCAAACAGGCTCTAGAGATTCGAAGTAGTTTATCTGAGAAGAGAGCACTTACTGATCCAATACAGGGAACAGAATATTCTGCTGAATCTC
TTGTGCGGAATCTACAGTGGGCCAAGGCTCATGAACTTCCAGAAAGTATGTGTCTTAAGTTTGACTGTGGTGTTCAGATTCAATTAGGAT
TTGCAGCTGAGTTTTCCAATGTCATGATCATCTATACAAGTATAGTTTACAAACCACCGGAGATAATAATGTGTGATGCCTACGTTACTG
ATTTTCCACTTGATCTAGATATTGATCCAAAAGATGCAAATAAAGGCACACCTGAAGAAACTGGCAGCTACTTGGTATCAAAGGATCTTC
CCAAGCATTGCCTCTATACCAGACTCAGTTCACTGCAAAAATTAAAGGAACATCTAGTCTTCACAGTATGTTTATCATATCAGTACTCAG
GATTGGAAGATACTGTAGAGGACAAGCAGGAAGTGAATGTTGGGAAACCTCTCATTGCTAAATTAGACATGCATCGAGGTTTGGGAAGGA
AGACTTGCTTTCAAACTTGTCTTATGTCTAATGGTCCTTACCAGAGTTCTGCAGCCACCTCAGGAGGAGCAGGGCATTATCACTCATTGC
AAGACCCATTCCATGGTGTTTACCATTCACATCCTGGTAATCCAAGTAATGTTACACCAGCAGATAGCTGTCATTGCAGCCGGACTCCAG
ATGCATTTATTTCAAGTTTCGCTCACCATGCTTCATGTCATTTTAGTAGAAGTAATGTGCCAGTAGAGACAACTGATGAAATACCATTTA
GTTTCTCTGACAGGCTCAGAATTTCTGAAAAATGACCTCCTTGTTTTTGAAAGTTAGCATAATTTTAGATGCCTGTGAAATAGTACTGCA
CTTACATAAAGTGAGACATTGTGAAAAGGCAAATTTGTATATGTAGAGAAAGAATAGTAGTAACTGTTTCATAGCAAACTTCAGGACTTT
GAGATGTTGAAATTACATTATTTAATTACAGACTTCCTCTTTCTAAGATTTTGTGAATTGGTTGAATAGTTCTATACAAATGAAGTATGG
AGGTGTGTATGTTTATATGTATATAACAAAATATTTTCATTGTGACCACTCTGAAGTAAGAGCAATGGGAATGGCATTATTGTAGAATAA
GTCATTGTATTTTTAACACCAGAAAGAACCTTGCCGATCACCAGGCATAACCTAATTTTATCCATGGAAGAAACACAGAAAGGCATCTAA
GTTAGAGCTGGCACCAGAACTGAGACCTCCAGAAATCTATTCCAGTATTTTTTCCACTACACAACTGCCTTCCTGACAGGTTCTGAGATA
AGTGTTATGTTTGTAGATAGAGTGAAATATATTTATATATATATAAATATATACAGATACATATCTGTGTATTATCTCAAGGAATGTACA
AACTTTAGTTTTTGATTATAAGGACTTCACTGCAAGTTTTAGTTAAGAGGTTTGTATATAAATCTGTTATAGAACAGGCTGAAATTTCTT
GTTCATAAGATTATGAAACCACATGAGAAGTGATAAAATGTTTGTTAAAGCTAGATAGAGGTTAAGAATCAAGATATAATGGATAATTTT
CATAGCTGCCTATCAGAATTTCCCAAATATTTAGCATCTTCCTTGATAATATGTATTTTCTTCTTGAATTTCACTGGCCTAATGAGATAA
TACTCTTATCTTTGGCTCTACCTAAAAGTTGGTTAAAAATGCAATTGGCATTAACAAGGAAAAATACTGAATTAGTAATTTTAAAAGTCT
CACAAAGAAAATCCCAGGCCTAGATGGCTGCATTGTTGAATTCTGCCAAACATTAAAATTAGCACTAATTTTTTGCACACTGTTTCTAAA
AGTAGGAGAGGAAAGAACACTTCCCAACTTACTCTAGGTCAGTATTACCCTGATACTAGACTAGACATCACAAGAAAACTATAAGCCAAT
ATTCCTTATTAATACAAACACAAAAATCATTAACAAAAATATTAGCAAACTGAATCCAGCAACCTATAAAAAGGATTCTATATCATGACC
AAGTGGAATTTATCCCAGGAATTCAAGGTTGGTTCAACATCTAAAAATCAAATAAGCTAATATACAGTCAGTTCTCATTATTCACAGTAA
TTATGTTCTACAGAATATTCTCCCATAAACACTGAATTAAATATGGAACAACTGCTTTTAGGAGAAAGTGTATTTGTGTATATGTGTGTA
TACATATGTTTATCTCACACACATTATGAGCTTGAATTCTTAATTCATCCTAGCAAATTCTACCTTATTTTACAGAAGTGAAAGTGAGGT
ATCAGAAGTGTTAAGTGACATGCCTGAGGCACCCCCCTAACAGGTGTCAGAGCTGAAATTCAAACCCCATCCAGCTGGCCCCGGAGCCAG
AGCTTCTTGTACTACACAGAATTGCCCCTGCCATTTCCACCCTCCAGTCATTTCTCTATGAGACTGAAGCAGGAAGGCAGAGCATCATCT
TGTTCAGCCTCAGCTGGGAACATGTGTACTGGGTGACTCAAATTTTTCACCCATTTACACATATCCACAAATGACTGCAAAAGTGCCACG
GATATCAATTTGAGGGTTATAAATTTTAGCAAGTTGGTAAATTCACAAATACATAACCTTGAATAATGAGGATCAACTGTACCATATTTA
ATAAAGCACAAAACCCACACAGATTGTCTTATTACAGCATTTGATAAAATCCAAAACTCTTTCATAAAAACACTCAACAAACTTAGGAAT
AAAAGGAATCTTCCTAGATATGATAAATATAACATCTATGAAAAGCCCACACCTAACATTATACTTCATGGTGATAGACTGAAGGCTGAA
TGTTTTCCCCTTAAGATTGGGAAGAAGGACAAGGATGTTCACTCGGCACTACTTCTATTCAGCATTGTACTTGAAGTTCTAGCCACAGCA
GTTAGGTTAGGAATTCAAGGTTTGTTCAACATCTAAAAATCAAATAAGCTAATAAAGAAAAGAGGTTTATACTGCAAAAGAAGTGAAACT

>9744_9744_4_BIRC3-MALT1_BIRC3_chr11_102201972_ENST00000532808_MALT1_chr18_56363597_ENST00000348428_length(amino acids)=1140AA_BP=442
MNIVENSIFLSNLMKSANTFELKYDLSCELYRMSTYSTFPAGVPVSERSLARAGFYYTGVNDKVKCFCCGLMLDNWKRGDSPTEKHKKLY
PSCRFVQSLNSVNNLEATSQPTFPSSVTNSTHSLLPGTENSGYFRGSYSNSPSNPVNSRANQDFSALMRSSYHCAMNNENARLLTFQTWP
LTFLSPTDLAKAGFYYIGPGDRVACFACGGKLSNWEPKDNAMSEHLRHFPKCPFIENQLQDTSRYTVSNLSMQTHAARFKTFFNWPSSVL
VNPEQLASAGFYYVGNSDDVKCFCCDGGLRCWESGDDPWVQHAKWFPRCEYLIRIKGQEFIRQVQASYPHLLEQLLSTSDSPGDENAESS
IIHFEPGEDHSEDAIMMNTPVINAAVEMGFSRSLVKQTVQRKILATGENYRLVNDLVLDLLNAEDEIREEERERATEEKESRIKITVNPE
SKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSELIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSE
SKLQICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHETKKLYMVPYVDLEHQGTYWCHVYNDRDSQDSKKVEIIIGRTDEA
VECTEDELNNLGHPDNKEQTTDQPLAKDKVALLIGNMNYREHPKLKAPLVDVYELTNLLRQLDFKVVSLLDLTEYEMRNAVDEFLLLLDK
GVYGLLYYAGHGYENFGNSFMVPVDAPNPYRSENCLCVQNILKLMQEKETGLNVFLLDMCRKRNDYDDTIPILDALKVTANIVFGYATCQ
GAEAFEIQHSGLANGIFMKFLKDRLLEDKKITVLLDEVAEDMGKCHLTKGKQALEIRSSLSEKRALTDPIQGTEYSAESLVRNLQWAKAH
ELPESMCLKFDCGVQIQLGFAAEFSNVMIIYTSIVYKPPEIIMCDAYVTDFPLDLDIDPKDANKGTPEETGSYLVSKDLPKHCLYTRLSS
LQKLKEHLVFTVCLSYQYSGLEDTVEDKQEVNVGKPLIAKLDMHRGLGRKTCFQTCLMSNGPYQSSAATSGGAGHYHSLQDPFHGVYHSH

--------------------------------------------------------------
>9744_9744_5_BIRC3-MALT1_BIRC3_chr11_102201973_ENST00000263464_MALT1_chr18_56363598_ENST00000345724_length(transcript)=6452nt_BP=4074nt
GGCCAGGCGACAGGTGTCGCTTGAAAAGACTGGGCTTGTCCTTGCTGGTGCATGCGTCGTCGGCCTCTGGGCAGCAGGTTTACAAAGGAG
GAAAACGACTTCTTCTAGATTTTTTTTTCAGTTTCTTCTATAAATCAAAACATCTCAAAATGGAGACCTAAAATCCTTAAAGGGACTTAG
TCTAATCTCGGGAGGTAGTTTTGTGCATGGGTAAACAAATTAAGTATTAACTGGTGTTTTACTATCCAAAGAATGCTAATTTTATAAACA
TGATCGAGTTATATAAGGTATACCATAATGAGTTTGATTTTGAATTTGATTTGTGGAAATAAAGGAAAAGTGATTCTAGCTGGGGCATAT
TGTTAAAGCATTTTTTTCAGAGTTGGCCAGGCAGTCTCCTACTGGCACATTCTCCCATTATGTAGAATAGAAATAGTACCTGTGTTTGGG
AAAGATTTTAAAATGAGTGACAGTTATTTGGAACAAAGAGCTAATAATCAATCCACTGCAAATTAAAGAAACATGCAGATGAAAGTTTTG
ACACATTAAAATACTTCTACAGTGACAAAGAAAAATCAAGAACAAAGCTTTTTGATATGTGCAACAAATTTAGAGGAAGTAAAAAGATAA
ATGTGATGATTGGTCAAGAAATTATCCAGTTATTTACAAGGCCACTGATATTTTAAACGTCCAAAAGTTTGTTTAAATGGGCTGTTACCG
CTGAGAATGATGAGGATGAGAATGATGGTTGAAGGTTACATTTTAGGAAATGAAGAAACTTAGAAAATTAATATAAAGACAGTGATGAAT
ACAAAGAAGATTTTTATAACAATGTGTAAAATTTTTGGCCAGGGAAAGGAATATTGAAGTTAGATACAATTACTTACCTTTGAGGGAAAT
AATTGTTGGTAATGAGATGTGATGTTTCTCCTGCCACCTGGAAACAAAGCATTGAAGTCTGCAGTTGAAAAGCCCAACGTCTGTGAGATC
CAGGAAACCATGCTTGCAAACCACTGGTAAAAAAAAAAAAAAAAAAAAAAAAAAGCCACAGTGACTTGCTTATTGGTCATTGCTAGTATT
ATCGACTCAGAACCTCTTTACTAATGGCTAGTAAATCATAATTGAGAAATTCTGAATTTTGACAAGGTCTCTGCTGTTGAAATGGTAAAT
TTATTATTTTTTTTGTCATGATAAATTCTGGTTCAAGGTATGCTATCCATGAAATAATTTCTGACCAAAACTAAATTGATGCAATTTGAT
TATCCATCTTAGCCTACAGATGGCATCTGGTAACTTTTGACTGTTTTAAAAAATAAATCCACTATCAGAGTAGATTTGATGTTGGCTTCA
GAAACATTTAGAAAAACAAAAGTTCAAAAATGTTTTCAGGAGGTGATAAGTTGAATAACTCTACAATGTTAGTTCTTTGAGGGGGACAAA
AAATTTAAAATCTTTGAAAGGTCTTATTTTACAGCCATATCTAAATTATCTTAAGAAAATTTTTAACAAAGGGAATGAAATATATATCAT
GATTCTGTTTTTCCAAAAGTAACCTGAATATAGCAATGAAGTTCAGTTTTGTTATTGGTAGTTTGGGCAGAGTCTCTTTTTGCAGCACCT
GTTGTCTACCATAATTACAGAGGACATTTCCATGTTCTAGCCAAGTATACTATTAGAATAAAAAAACTTAACATTGAGTTGCTTCAACAG
CATGAAACTGAGTCCAAAAGACCAAATGAACAAACACATTAATCTCTGATTATTTATTTTAAATAGAATATTTAATTGTGTAAGATCTAA
TAGTATCATTATACTTAAGCAATCATATTCCTGATGATCTATGGGAAATAACTATTATTTAATTAATATTGAAACCAGGTTTTAAGATGT
GTTAGCCAGTCCTGTTACTAGTAAATCTCTTTATTTGGAGAGAAATTTTAGATTGTTTTGTTCTCCTTATTAGAAGGATTGTAGAAAGAA
AAAAATGACTAATTGGAGAAAAATTGGGGATATATCATATTTCACTGAATTCAAAATGTCTTCAGTTGTAAATCTTACCATTATTTTACG
TACCTCTAAGAAATAAAAGTGCTTCTAATTAAAATATGATGTCATTAATTATGAAATACTTCTTGATAACAGAAGTTTTAAAATAGCCAT
CTTAGAATCAGTGAAATATGGTAATGTATTATTTTCCTCCTTTGAGTTAGGTCTTGTGCTTTTTTTTCCTGGCCACTAAATTTCACAATT
TCCAAAAAGCAAAATAAACATATTCTGAATATTTTTGCTGTGAAACACTTGACAGCAGAGCTTTCCACCATGAAAAGAAGCTTCATGAGT
CACACATTACATCTTTGGGTTGATTGAATGCCACTGAAACATTCTAGTAGCCTGGAGAAGTTGACCTACCTGTGGAGATGCCTGCCATTA
AATGGCATCCTGATGGCTTAATACACATCACTCTTCTGTGAAGGGTTTTAATTTTCAACACAGCTTACTCTGTAGCATCATGTTTACATT
GTATGTATAAAGATTATACAAAGGTGCAATTGTGTATTTCTTCCTTAAAATGTATCAGTATAGGATTTAGAATCTCCATGTTGAAACTCT
AAATGCATAGAAATAAAAATAATAAAAAATTTTTCATTTTGGCTTTTCAGCCTAGTATTAAAACTGATAAAAGCAAAGCCATGCACAAAA
CTACCTCCCTAGAGAAAGGCTAGTCCCTTTTCTTCCCCATTCATTTCATTATGAACATAGTAGAAAACAGCATATTCTTATCAAATTTGA
TGAAAAGCGCCAACACGTTTGAACTGAAATACGACTTGTCATGTGAACTGTACCGAATGTCTACGTATTCCACTTTTCCTGCTGGGGTTC
CTGTCTCAGAAAGGAGTCTTGCTCGTGCTGGTTTCTATTACACTGGTGTGAATGACAAGGTCAAATGCTTCTGTTGTGGCCTGATGCTGG
ATAACTGGAAAAGAGGAGACAGTCCTACTGAAAAGCATAAAAAGTTGTATCCTAGCTGCAGATTCGTTCAGAGTCTAAATTCCGTTAACA
ACTTGGAAGCTACCTCTCAGCCTACTTTTCCTTCTTCAGTAACAAATTCCACACACTCATTACTTCCGGGTACAGAAAACAGTGGATATT
TCCGTGGCTCTTATTCAAACTCTCCATCAAATCCTGTAAACTCCAGAGCAAATCAAGATTTTTCTGCCTTGATGAGAAGTTCCTACCACT
GTGCAATGAATAACGAAAATGCCAGATTACTTACTTTTCAGACATGGCCATTGACTTTTCTGTCGCCAACAGATCTGGCAAAAGCAGGCT
TTTACTACATAGGACCTGGAGACAGAGTGGCTTGCTTTGCCTGTGGTGGAAAATTGAGCAATTGGGAACCGAAGGATAATGCTATGTCAG
AACACCTGAGACATTTTCCCAAATGCCCATTTATAGAAAATCAGCTTCAAGACACTTCAAGATACACAGTTTCTAATCTGAGCATGCAGA
CACATGCAGCCCGCTTTAAAACATTCTTTAACTGGCCCTCTAGTGTTCTAGTTAATCCTGAGCAGCTTGCAAGTGCGGGTTTTTATTATG
TGGGTAACAGTGATGATGTCAAATGCTTTTGCTGTGATGGTGGACTCAGGTGTTGGGAATCTGGAGATGATCCATGGGTTCAACATGCCA
AGTGGTTTCCAAGGTGTGAGTACTTGATAAGAATTAAAGGACAGGAGTTCATCCGTCAAGTTCAAGCCAGTTACCCTCATCTACTTGAAC
AGCTGCTATCCACATCAGACAGCCCAGGAGATGAAAATGCAGAGTCATCAATTATCCATTTTGAACCTGGAGAAGACCATTCAGAAGATG
CAATCATGATGAATACTCCTGTGATTAATGCTGCCGTGGAAATGGGCTTTAGTAGAAGCCTGGTAAAACAGACAGTTCAGAGAAAAATCC
TAGCAACTGGAGAGAATTATAGACTAGTCAATGATCTTGTGTTAGACTTACTCAATGCAGAAGATGAAATAAGGGAAGAGGAGAGAGAAA
GAGCAACTGAGGAAAAAGAATCAAGAATAAAGATTACTGTAAACCCAGAGTCAAAGGCAGTCTTGGCTGGACAGTTTGTGAAACTGTGTT
GCCGGGCAACTGGACATCCTTTTGTTCAATATCAGTGGTTCAAAATGAATAAAGAGATTCCAAATGGAAATACATCAGAGCTTATTTTTA
ATGCAGTGCATGTAAAAGATGCAGGCTTTTATGTCTGTCGAGTTAATAACAATTTCACCTTTGAATTCAGCCAGTGGTCACAGCTGGATG
TTTGCGACATCCCAGAGAGCTTCCAGAGAAGTGTTGATGGCGTCTCTGAATCCAAGTTGCAAATCTGTGTTGAACCAACTTCCCAAAAGC
TGATGCCAGGCAGCACATTGGTTTTACAGTGTGTTGCTGTTGGAAGCCCTATTCCTCACTACCAGTGGTTCAAAAATGAATTACCATTAA
CACATGAGACCAAAAAGCTATACATGGTGCCTTATGTGGATTTGGAACACCAAGGAACCTACTGGTGTCATGTATATAATGATCGAGACA
GTCAAGATAGCAAGAAGGTAGAAATCATCATAGATGAATTAAATAATCTTGGTCATCCTGATAATAAAGAGCAAACAACTGACCAGCCTT
TGGCGAAGGACAAGGTTGCCCTTTTGATAGGAAATATGAATTACCGGGAGCACCCCAAGCTCAAAGCTCCTTTGGTGGATGTGTACGAAT
TGACTAACTTACTGAGACAGCTGGACTTCAAAGTGGTTTCACTGTTGGATCTTACTGAATATGAGATGCGTAATGCTGTGGATGAGTTTT
TACTCCTTTTAGACAAGGGAGTATATGGGTTATTATATTATGCAGGACATGGTTATGAAAATTTTGGGAACAGCTTCATGGTCCCCGTTG
ATGCTCCAAATCCATATAGGTCTGAAAATTGTCTGTGTGTACAAAATATACTGAAATTGATGCAAGAAAAAGAAACTGGACTTAATGTGT
TCTTATTGGATATGTGTAGGAAAAGAAATGACTACGATGATACCATTCCAATCTTGGATGCACTAAAAGTCACCGCCAATATTGTGTTTG
GATATGCCACGTGTCAAGGAGCAGAAGCTTTTGAAATCCAGCATTCTGGATTGGCAAATGGAATCTTTATGAAATTTTTAAAAGACAGAT
TATTAGAAGATAAGAAAATCACTGTGTTACTGGATGAAGTTGCAGAAGATATGGGTAAGTGTCACCTTACCAAAGGCAAACAGGCTCTAG
AGATTCGAAGTAGTTTATCTGAGAAGAGAGCACTTACTGATCCAATACAGGGAACAGAATATTCTGCTGAATCTCTTGTGCGGAATCTAC
AGTGGGCCAAGGCTCATGAACTTCCAGAAAGTATGTGTCTTAAGTTTGACTGTGGTGTTCAGATTCAATTAGGATTTGCAGCTGAGTTTT
CCAATGTCATGATCATCTATACAAGTATAGTTTACAAACCACCGGAGATAATAATGTGTGATGCCTACGTTACTGATTTTCCACTTGATC
TAGATATTGATCCAAAAGATGCAAATAAAGGCACACCTGAAGAAACTGGCAGCTACTTGGTATCAAAGGATCTTCCCAAGCATTGCCTCT
ATACCAGACTCAGTTCACTGCAAAAATTAAAGGAACATCTAGTCTTCACAGTATGTTTATCATATCAGTACTCAGGATTGGAAGATACTG
TAGAGGACAAGCAGGAAGTGAATGTTGGGAAACCTCTCATTGCTAAATTAGACATGCATCGAGGTTTGGGAAGGAAGACTTGCTTTCAAA
CTTGTCTTATGTCTAATGGTCCTTACCAGAGTTCTGCAGCCACCTCAGGAGGAGCAGGGCATTATCACTCATTGCAAGACCCATTCCATG
GTGTTTACCATTCACATCCTGGTAATCCAAGTAATGTTACACCAGCAGATAGCTGTCATTGCAGCCGGACTCCAGATGCATTTATTTCAA
GTTTCGCTCACCATGCTTCATGTCATTTTAGTAGAAGTAATGTGCCAGTAGAGACAACTGATGAAATACCATTTAGTTTCTCTGACAGGC
TCAGAATTTCTGAAAAATGACCTCCTTGTTTTTGAAAGTTAGCATAATTTTAGATGCCTGTGAAATAGTACTGCACTTACATAAAGTGAG
ACATTGTGAAAAGGCAAATTTGTATATGTAGAGAAAGAATAGTAGTAACTGTTTCATAGCAAACTTCAGGACTTTGAGATGTTGAAATTA
CATTATTTAATTACAGACTTCCTCTTTCTAAGATTTTGTGAATTGGTTGAATAGTTCTATACAAATGAAGTATGGAGGTGTGTATGTTTA

>9744_9744_5_BIRC3-MALT1_BIRC3_chr11_102201973_ENST00000263464_MALT1_chr18_56363598_ENST00000345724_length(amino acids)=1129AA_BP=442
MNIVENSIFLSNLMKSANTFELKYDLSCELYRMSTYSTFPAGVPVSERSLARAGFYYTGVNDKVKCFCCGLMLDNWKRGDSPTEKHKKLY
PSCRFVQSLNSVNNLEATSQPTFPSSVTNSTHSLLPGTENSGYFRGSYSNSPSNPVNSRANQDFSALMRSSYHCAMNNENARLLTFQTWP
LTFLSPTDLAKAGFYYIGPGDRVACFACGGKLSNWEPKDNAMSEHLRHFPKCPFIENQLQDTSRYTVSNLSMQTHAARFKTFFNWPSSVL
VNPEQLASAGFYYVGNSDDVKCFCCDGGLRCWESGDDPWVQHAKWFPRCEYLIRIKGQEFIRQVQASYPHLLEQLLSTSDSPGDENAESS
IIHFEPGEDHSEDAIMMNTPVINAAVEMGFSRSLVKQTVQRKILATGENYRLVNDLVLDLLNAEDEIREEERERATEEKESRIKITVNPE
SKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSELIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSE
SKLQICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHETKKLYMVPYVDLEHQGTYWCHVYNDRDSQDSKKVEIIIDELNNL
GHPDNKEQTTDQPLAKDKVALLIGNMNYREHPKLKAPLVDVYELTNLLRQLDFKVVSLLDLTEYEMRNAVDEFLLLLDKGVYGLLYYAGH
GYENFGNSFMVPVDAPNPYRSENCLCVQNILKLMQEKETGLNVFLLDMCRKRNDYDDTIPILDALKVTANIVFGYATCQGAEAFEIQHSG
LANGIFMKFLKDRLLEDKKITVLLDEVAEDMGKCHLTKGKQALEIRSSLSEKRALTDPIQGTEYSAESLVRNLQWAKAHELPESMCLKFD
CGVQIQLGFAAEFSNVMIIYTSIVYKPPEIIMCDAYVTDFPLDLDIDPKDANKGTPEETGSYLVSKDLPKHCLYTRLSSLQKLKEHLVFT
VCLSYQYSGLEDTVEDKQEVNVGKPLIAKLDMHRGLGRKTCFQTCLMSNGPYQSSAATSGGAGHYHSLQDPFHGVYHSHPGNPSNVTPAD

--------------------------------------------------------------
>9744_9744_6_BIRC3-MALT1_BIRC3_chr11_102201973_ENST00000263464_MALT1_chr18_56363598_ENST00000348428_length(transcript)=8470nt_BP=4074nt
GGCCAGGCGACAGGTGTCGCTTGAAAAGACTGGGCTTGTCCTTGCTGGTGCATGCGTCGTCGGCCTCTGGGCAGCAGGTTTACAAAGGAG
GAAAACGACTTCTTCTAGATTTTTTTTTCAGTTTCTTCTATAAATCAAAACATCTCAAAATGGAGACCTAAAATCCTTAAAGGGACTTAG
TCTAATCTCGGGAGGTAGTTTTGTGCATGGGTAAACAAATTAAGTATTAACTGGTGTTTTACTATCCAAAGAATGCTAATTTTATAAACA
TGATCGAGTTATATAAGGTATACCATAATGAGTTTGATTTTGAATTTGATTTGTGGAAATAAAGGAAAAGTGATTCTAGCTGGGGCATAT
TGTTAAAGCATTTTTTTCAGAGTTGGCCAGGCAGTCTCCTACTGGCACATTCTCCCATTATGTAGAATAGAAATAGTACCTGTGTTTGGG
AAAGATTTTAAAATGAGTGACAGTTATTTGGAACAAAGAGCTAATAATCAATCCACTGCAAATTAAAGAAACATGCAGATGAAAGTTTTG
ACACATTAAAATACTTCTACAGTGACAAAGAAAAATCAAGAACAAAGCTTTTTGATATGTGCAACAAATTTAGAGGAAGTAAAAAGATAA
ATGTGATGATTGGTCAAGAAATTATCCAGTTATTTACAAGGCCACTGATATTTTAAACGTCCAAAAGTTTGTTTAAATGGGCTGTTACCG
CTGAGAATGATGAGGATGAGAATGATGGTTGAAGGTTACATTTTAGGAAATGAAGAAACTTAGAAAATTAATATAAAGACAGTGATGAAT
ACAAAGAAGATTTTTATAACAATGTGTAAAATTTTTGGCCAGGGAAAGGAATATTGAAGTTAGATACAATTACTTACCTTTGAGGGAAAT
AATTGTTGGTAATGAGATGTGATGTTTCTCCTGCCACCTGGAAACAAAGCATTGAAGTCTGCAGTTGAAAAGCCCAACGTCTGTGAGATC
CAGGAAACCATGCTTGCAAACCACTGGTAAAAAAAAAAAAAAAAAAAAAAAAAAGCCACAGTGACTTGCTTATTGGTCATTGCTAGTATT
ATCGACTCAGAACCTCTTTACTAATGGCTAGTAAATCATAATTGAGAAATTCTGAATTTTGACAAGGTCTCTGCTGTTGAAATGGTAAAT
TTATTATTTTTTTTGTCATGATAAATTCTGGTTCAAGGTATGCTATCCATGAAATAATTTCTGACCAAAACTAAATTGATGCAATTTGAT
TATCCATCTTAGCCTACAGATGGCATCTGGTAACTTTTGACTGTTTTAAAAAATAAATCCACTATCAGAGTAGATTTGATGTTGGCTTCA
GAAACATTTAGAAAAACAAAAGTTCAAAAATGTTTTCAGGAGGTGATAAGTTGAATAACTCTACAATGTTAGTTCTTTGAGGGGGACAAA
AAATTTAAAATCTTTGAAAGGTCTTATTTTACAGCCATATCTAAATTATCTTAAGAAAATTTTTAACAAAGGGAATGAAATATATATCAT
GATTCTGTTTTTCCAAAAGTAACCTGAATATAGCAATGAAGTTCAGTTTTGTTATTGGTAGTTTGGGCAGAGTCTCTTTTTGCAGCACCT
GTTGTCTACCATAATTACAGAGGACATTTCCATGTTCTAGCCAAGTATACTATTAGAATAAAAAAACTTAACATTGAGTTGCTTCAACAG
CATGAAACTGAGTCCAAAAGACCAAATGAACAAACACATTAATCTCTGATTATTTATTTTAAATAGAATATTTAATTGTGTAAGATCTAA
TAGTATCATTATACTTAAGCAATCATATTCCTGATGATCTATGGGAAATAACTATTATTTAATTAATATTGAAACCAGGTTTTAAGATGT
GTTAGCCAGTCCTGTTACTAGTAAATCTCTTTATTTGGAGAGAAATTTTAGATTGTTTTGTTCTCCTTATTAGAAGGATTGTAGAAAGAA
AAAAATGACTAATTGGAGAAAAATTGGGGATATATCATATTTCACTGAATTCAAAATGTCTTCAGTTGTAAATCTTACCATTATTTTACG
TACCTCTAAGAAATAAAAGTGCTTCTAATTAAAATATGATGTCATTAATTATGAAATACTTCTTGATAACAGAAGTTTTAAAATAGCCAT
CTTAGAATCAGTGAAATATGGTAATGTATTATTTTCCTCCTTTGAGTTAGGTCTTGTGCTTTTTTTTCCTGGCCACTAAATTTCACAATT
TCCAAAAAGCAAAATAAACATATTCTGAATATTTTTGCTGTGAAACACTTGACAGCAGAGCTTTCCACCATGAAAAGAAGCTTCATGAGT
CACACATTACATCTTTGGGTTGATTGAATGCCACTGAAACATTCTAGTAGCCTGGAGAAGTTGACCTACCTGTGGAGATGCCTGCCATTA
AATGGCATCCTGATGGCTTAATACACATCACTCTTCTGTGAAGGGTTTTAATTTTCAACACAGCTTACTCTGTAGCATCATGTTTACATT
GTATGTATAAAGATTATACAAAGGTGCAATTGTGTATTTCTTCCTTAAAATGTATCAGTATAGGATTTAGAATCTCCATGTTGAAACTCT
AAATGCATAGAAATAAAAATAATAAAAAATTTTTCATTTTGGCTTTTCAGCCTAGTATTAAAACTGATAAAAGCAAAGCCATGCACAAAA
CTACCTCCCTAGAGAAAGGCTAGTCCCTTTTCTTCCCCATTCATTTCATTATGAACATAGTAGAAAACAGCATATTCTTATCAAATTTGA
TGAAAAGCGCCAACACGTTTGAACTGAAATACGACTTGTCATGTGAACTGTACCGAATGTCTACGTATTCCACTTTTCCTGCTGGGGTTC
CTGTCTCAGAAAGGAGTCTTGCTCGTGCTGGTTTCTATTACACTGGTGTGAATGACAAGGTCAAATGCTTCTGTTGTGGCCTGATGCTGG
ATAACTGGAAAAGAGGAGACAGTCCTACTGAAAAGCATAAAAAGTTGTATCCTAGCTGCAGATTCGTTCAGAGTCTAAATTCCGTTAACA
ACTTGGAAGCTACCTCTCAGCCTACTTTTCCTTCTTCAGTAACAAATTCCACACACTCATTACTTCCGGGTACAGAAAACAGTGGATATT
TCCGTGGCTCTTATTCAAACTCTCCATCAAATCCTGTAAACTCCAGAGCAAATCAAGATTTTTCTGCCTTGATGAGAAGTTCCTACCACT
GTGCAATGAATAACGAAAATGCCAGATTACTTACTTTTCAGACATGGCCATTGACTTTTCTGTCGCCAACAGATCTGGCAAAAGCAGGCT
TTTACTACATAGGACCTGGAGACAGAGTGGCTTGCTTTGCCTGTGGTGGAAAATTGAGCAATTGGGAACCGAAGGATAATGCTATGTCAG
AACACCTGAGACATTTTCCCAAATGCCCATTTATAGAAAATCAGCTTCAAGACACTTCAAGATACACAGTTTCTAATCTGAGCATGCAGA
CACATGCAGCCCGCTTTAAAACATTCTTTAACTGGCCCTCTAGTGTTCTAGTTAATCCTGAGCAGCTTGCAAGTGCGGGTTTTTATTATG
TGGGTAACAGTGATGATGTCAAATGCTTTTGCTGTGATGGTGGACTCAGGTGTTGGGAATCTGGAGATGATCCATGGGTTCAACATGCCA
AGTGGTTTCCAAGGTGTGAGTACTTGATAAGAATTAAAGGACAGGAGTTCATCCGTCAAGTTCAAGCCAGTTACCCTCATCTACTTGAAC
AGCTGCTATCCACATCAGACAGCCCAGGAGATGAAAATGCAGAGTCATCAATTATCCATTTTGAACCTGGAGAAGACCATTCAGAAGATG
CAATCATGATGAATACTCCTGTGATTAATGCTGCCGTGGAAATGGGCTTTAGTAGAAGCCTGGTAAAACAGACAGTTCAGAGAAAAATCC
TAGCAACTGGAGAGAATTATAGACTAGTCAATGATCTTGTGTTAGACTTACTCAATGCAGAAGATGAAATAAGGGAAGAGGAGAGAGAAA
GAGCAACTGAGGAAAAAGAATCAAGAATAAAGATTACTGTAAACCCAGAGTCAAAGGCAGTCTTGGCTGGACAGTTTGTGAAACTGTGTT
GCCGGGCAACTGGACATCCTTTTGTTCAATATCAGTGGTTCAAAATGAATAAAGAGATTCCAAATGGAAATACATCAGAGCTTATTTTTA
ATGCAGTGCATGTAAAAGATGCAGGCTTTTATGTCTGTCGAGTTAATAACAATTTCACCTTTGAATTCAGCCAGTGGTCACAGCTGGATG
TTTGCGACATCCCAGAGAGCTTCCAGAGAAGTGTTGATGGCGTCTCTGAATCCAAGTTGCAAATCTGTGTTGAACCAACTTCCCAAAAGC
TGATGCCAGGCAGCACATTGGTTTTACAGTGTGTTGCTGTTGGAAGCCCTATTCCTCACTACCAGTGGTTCAAAAATGAATTACCATTAA
CACATGAGACCAAAAAGCTATACATGGTGCCTTATGTGGATTTGGAACACCAAGGAACCTACTGGTGTCATGTATATAATGATCGAGACA
GTCAAGATAGCAAGAAGGTAGAAATCATCATAGGAAGAACAGATGAGGCAGTGGAGTGCACTGAAGATGAATTAAATAATCTTGGTCATC
CTGATAATAAAGAGCAAACAACTGACCAGCCTTTGGCGAAGGACAAGGTTGCCCTTTTGATAGGAAATATGAATTACCGGGAGCACCCCA
AGCTCAAAGCTCCTTTGGTGGATGTGTACGAATTGACTAACTTACTGAGACAGCTGGACTTCAAAGTGGTTTCACTGTTGGATCTTACTG
AATATGAGATGCGTAATGCTGTGGATGAGTTTTTACTCCTTTTAGACAAGGGAGTATATGGGTTATTATATTATGCAGGACATGGTTATG
AAAATTTTGGGAACAGCTTCATGGTCCCCGTTGATGCTCCAAATCCATATAGGTCTGAAAATTGTCTGTGTGTACAAAATATACTGAAAT
TGATGCAAGAAAAAGAAACTGGACTTAATGTGTTCTTATTGGATATGTGTAGGAAAAGAAATGACTACGATGATACCATTCCAATCTTGG
ATGCACTAAAAGTCACCGCCAATATTGTGTTTGGATATGCCACGTGTCAAGGAGCAGAAGCTTTTGAAATCCAGCATTCTGGATTGGCAA
ATGGAATCTTTATGAAATTTTTAAAAGACAGATTATTAGAAGATAAGAAAATCACTGTGTTACTGGATGAAGTTGCAGAAGATATGGGTA
AGTGTCACCTTACCAAAGGCAAACAGGCTCTAGAGATTCGAAGTAGTTTATCTGAGAAGAGAGCACTTACTGATCCAATACAGGGAACAG
AATATTCTGCTGAATCTCTTGTGCGGAATCTACAGTGGGCCAAGGCTCATGAACTTCCAGAAAGTATGTGTCTTAAGTTTGACTGTGGTG
TTCAGATTCAATTAGGATTTGCAGCTGAGTTTTCCAATGTCATGATCATCTATACAAGTATAGTTTACAAACCACCGGAGATAATAATGT
GTGATGCCTACGTTACTGATTTTCCACTTGATCTAGATATTGATCCAAAAGATGCAAATAAAGGCACACCTGAAGAAACTGGCAGCTACT
TGGTATCAAAGGATCTTCCCAAGCATTGCCTCTATACCAGACTCAGTTCACTGCAAAAATTAAAGGAACATCTAGTCTTCACAGTATGTT
TATCATATCAGTACTCAGGATTGGAAGATACTGTAGAGGACAAGCAGGAAGTGAATGTTGGGAAACCTCTCATTGCTAAATTAGACATGC
ATCGAGGTTTGGGAAGGAAGACTTGCTTTCAAACTTGTCTTATGTCTAATGGTCCTTACCAGAGTTCTGCAGCCACCTCAGGAGGAGCAG
GGCATTATCACTCATTGCAAGACCCATTCCATGGTGTTTACCATTCACATCCTGGTAATCCAAGTAATGTTACACCAGCAGATAGCTGTC
ATTGCAGCCGGACTCCAGATGCATTTATTTCAAGTTTCGCTCACCATGCTTCATGTCATTTTAGTAGAAGTAATGTGCCAGTAGAGACAA
CTGATGAAATACCATTTAGTTTCTCTGACAGGCTCAGAATTTCTGAAAAATGACCTCCTTGTTTTTGAAAGTTAGCATAATTTTAGATGC
CTGTGAAATAGTACTGCACTTACATAAAGTGAGACATTGTGAAAAGGCAAATTTGTATATGTAGAGAAAGAATAGTAGTAACTGTTTCAT
AGCAAACTTCAGGACTTTGAGATGTTGAAATTACATTATTTAATTACAGACTTCCTCTTTCTAAGATTTTGTGAATTGGTTGAATAGTTC
TATACAAATGAAGTATGGAGGTGTGTATGTTTATATGTATATAACAAAATATTTTCATTGTGACCACTCTGAAGTAAGAGCAATGGGAAT
GGCATTATTGTAGAATAAGTCATTGTATTTTTAACACCAGAAAGAACCTTGCCGATCACCAGGCATAACCTAATTTTATCCATGGAAGAA
ACACAGAAAGGCATCTAAGTTAGAGCTGGCACCAGAACTGAGACCTCCAGAAATCTATTCCAGTATTTTTTCCACTACACAACTGCCTTC
CTGACAGGTTCTGAGATAAGTGTTATGTTTGTAGATAGAGTGAAATATATTTATATATATATAAATATATACAGATACATATCTGTGTAT
TATCTCAAGGAATGTACAAACTTTAGTTTTTGATTATAAGGACTTCACTGCAAGTTTTAGTTAAGAGGTTTGTATATAAATCTGTTATAG
AACAGGCTGAAATTTCTTGTTCATAAGATTATGAAACCACATGAGAAGTGATAAAATGTTTGTTAAAGCTAGATAGAGGTTAAGAATCAA
GATATAATGGATAATTTTCATAGCTGCCTATCAGAATTTCCCAAATATTTAGCATCTTCCTTGATAATATGTATTTTCTTCTTGAATTTC
ACTGGCCTAATGAGATAATACTCTTATCTTTGGCTCTACCTAAAAGTTGGTTAAAAATGCAATTGGCATTAACAAGGAAAAATACTGAAT
TAGTAATTTTAAAAGTCTCACAAAGAAAATCCCAGGCCTAGATGGCTGCATTGTTGAATTCTGCCAAACATTAAAATTAGCACTAATTTT
TTGCACACTGTTTCTAAAAGTAGGAGAGGAAAGAACACTTCCCAACTTACTCTAGGTCAGTATTACCCTGATACTAGACTAGACATCACA
AGAAAACTATAAGCCAATATTCCTTATTAATACAAACACAAAAATCATTAACAAAAATATTAGCAAACTGAATCCAGCAACCTATAAAAA
GGATTCTATATCATGACCAAGTGGAATTTATCCCAGGAATTCAAGGTTGGTTCAACATCTAAAAATCAAATAAGCTAATATACAGTCAGT
TCTCATTATTCACAGTAATTATGTTCTACAGAATATTCTCCCATAAACACTGAATTAAATATGGAACAACTGCTTTTAGGAGAAAGTGTA
TTTGTGTATATGTGTGTATACATATGTTTATCTCACACACATTATGAGCTTGAATTCTTAATTCATCCTAGCAAATTCTACCTTATTTTA
CAGAAGTGAAAGTGAGGTATCAGAAGTGTTAAGTGACATGCCTGAGGCACCCCCCTAACAGGTGTCAGAGCTGAAATTCAAACCCCATCC
AGCTGGCCCCGGAGCCAGAGCTTCTTGTACTACACAGAATTGCCCCTGCCATTTCCACCCTCCAGTCATTTCTCTATGAGACTGAAGCAG
GAAGGCAGAGCATCATCTTGTTCAGCCTCAGCTGGGAACATGTGTACTGGGTGACTCAAATTTTTCACCCATTTACACATATCCACAAAT
GACTGCAAAAGTGCCACGGATATCAATTTGAGGGTTATAAATTTTAGCAAGTTGGTAAATTCACAAATACATAACCTTGAATAATGAGGA
TCAACTGTACCATATTTAATAAAGCACAAAACCCACACAGATTGTCTTATTACAGCATTTGATAAAATCCAAAACTCTTTCATAAAAACA
CTCAACAAACTTAGGAATAAAAGGAATCTTCCTAGATATGATAAATATAACATCTATGAAAAGCCCACACCTAACATTATACTTCATGGT
GATAGACTGAAGGCTGAATGTTTTCCCCTTAAGATTGGGAAGAAGGACAAGGATGTTCACTCGGCACTACTTCTATTCAGCATTGTACTT
GAAGTTCTAGCCACAGCAGTTAGGTTAGGAATTCAAGGTTTGTTCAACATCTAAAAATCAAATAAGCTAATAAAGAAAAGAGGTTTATAC
TGCAAAAGAAGTGAAACTATATGTATTCACAGTTGATACATAGTTGTATATAGAAAATGCTAAAGAATCCATAAAAAGTAATAAATGAGT

>9744_9744_6_BIRC3-MALT1_BIRC3_chr11_102201973_ENST00000263464_MALT1_chr18_56363598_ENST00000348428_length(amino acids)=1140AA_BP=442
MNIVENSIFLSNLMKSANTFELKYDLSCELYRMSTYSTFPAGVPVSERSLARAGFYYTGVNDKVKCFCCGLMLDNWKRGDSPTEKHKKLY
PSCRFVQSLNSVNNLEATSQPTFPSSVTNSTHSLLPGTENSGYFRGSYSNSPSNPVNSRANQDFSALMRSSYHCAMNNENARLLTFQTWP
LTFLSPTDLAKAGFYYIGPGDRVACFACGGKLSNWEPKDNAMSEHLRHFPKCPFIENQLQDTSRYTVSNLSMQTHAARFKTFFNWPSSVL
VNPEQLASAGFYYVGNSDDVKCFCCDGGLRCWESGDDPWVQHAKWFPRCEYLIRIKGQEFIRQVQASYPHLLEQLLSTSDSPGDENAESS
IIHFEPGEDHSEDAIMMNTPVINAAVEMGFSRSLVKQTVQRKILATGENYRLVNDLVLDLLNAEDEIREEERERATEEKESRIKITVNPE
SKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSELIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSE
SKLQICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHETKKLYMVPYVDLEHQGTYWCHVYNDRDSQDSKKVEIIIGRTDEA
VECTEDELNNLGHPDNKEQTTDQPLAKDKVALLIGNMNYREHPKLKAPLVDVYELTNLLRQLDFKVVSLLDLTEYEMRNAVDEFLLLLDK
GVYGLLYYAGHGYENFGNSFMVPVDAPNPYRSENCLCVQNILKLMQEKETGLNVFLLDMCRKRNDYDDTIPILDALKVTANIVFGYATCQ
GAEAFEIQHSGLANGIFMKFLKDRLLEDKKITVLLDEVAEDMGKCHLTKGKQALEIRSSLSEKRALTDPIQGTEYSAESLVRNLQWAKAH
ELPESMCLKFDCGVQIQLGFAAEFSNVMIIYTSIVYKPPEIIMCDAYVTDFPLDLDIDPKDANKGTPEETGSYLVSKDLPKHCLYTRLSS
LQKLKEHLVFTVCLSYQYSGLEDTVEDKQEVNVGKPLIAKLDMHRGLGRKTCFQTCLMSNGPYQSSAATSGGAGHYHSLQDPFHGVYHSH

--------------------------------------------------------------
>9744_9744_7_BIRC3-MALT1_BIRC3_chr11_102201973_ENST00000532808_MALT1_chr18_56363598_ENST00000345724_length(transcript)=3824nt_BP=1446nt
GGGCAGCAGGTTTACAAAGGAGGAAAACGACTTCTTCTAGATTTTTTTTTCAGTTTCTTCTATAAATCAAAACTACCTCCCTAGAGAAAG
GCTAGTCCCTTTTCTTCCCCATTCATTTCATTATGAACATAGTAGAAAACAGCATATTCTTATCAAATTTGATGAAAAGCGCCAACACGT
TTGAACTGAAATACGACTTGTCATGTGAACTGTACCGAATGTCTACGTATTCCACTTTTCCTGCTGGGGTTCCTGTCTCAGAAAGGAGTC
TTGCTCGTGCTGGTTTCTATTACACTGGTGTGAATGACAAGGTCAAATGCTTCTGTTGTGGCCTGATGCTGGATAACTGGAAAAGAGGAG
ACAGTCCTACTGAAAAGCATAAAAAGTTGTATCCTAGCTGCAGATTCGTTCAGAGTCTAAATTCCGTTAACAACTTGGAAGCTACCTCTC
AGCCTACTTTTCCTTCTTCAGTAACAAATTCCACACACTCATTACTTCCGGGTACAGAAAACAGTGGATATTTCCGTGGCTCTTATTCAA
ACTCTCCATCAAATCCTGTAAACTCCAGAGCAAATCAAGATTTTTCTGCCTTGATGAGAAGTTCCTACCACTGTGCAATGAATAACGAAA
ATGCCAGATTACTTACTTTTCAGACATGGCCATTGACTTTTCTGTCGCCAACAGATCTGGCAAAAGCAGGCTTTTACTACATAGGACCTG
GAGACAGAGTGGCTTGCTTTGCCTGTGGTGGAAAATTGAGCAATTGGGAACCGAAGGATAATGCTATGTCAGAACACCTGAGACATTTTC
CCAAATGCCCATTTATAGAAAATCAGCTTCAAGACACTTCAAGATACACAGTTTCTAATCTGAGCATGCAGACACATGCAGCCCGCTTTA
AAACATTCTTTAACTGGCCCTCTAGTGTTCTAGTTAATCCTGAGCAGCTTGCAAGTGCGGGTTTTTATTATGTGGGTAACAGTGATGATG
TCAAATGCTTTTGCTGTGATGGTGGACTCAGGTGTTGGGAATCTGGAGATGATCCATGGGTTCAACATGCCAAGTGGTTTCCAAGGTGTG
AGTACTTGATAAGAATTAAAGGACAGGAGTTCATCCGTCAAGTTCAAGCCAGTTACCCTCATCTACTTGAACAGCTGCTATCCACATCAG
ACAGCCCAGGAGATGAAAATGCAGAGTCATCAATTATCCATTTTGAACCTGGAGAAGACCATTCAGAAGATGCAATCATGATGAATACTC
CTGTGATTAATGCTGCCGTGGAAATGGGCTTTAGTAGAAGCCTGGTAAAACAGACAGTTCAGAGAAAAATCCTAGCAACTGGAGAGAATT
ATAGACTAGTCAATGATCTTGTGTTAGACTTACTCAATGCAGAAGATGAAATAAGGGAAGAGGAGAGAGAAAGAGCAACTGAGGAAAAAG
AATCAAGAATAAAGATTACTGTAAACCCAGAGTCAAAGGCAGTCTTGGCTGGACAGTTTGTGAAACTGTGTTGCCGGGCAACTGGACATC
CTTTTGTTCAATATCAGTGGTTCAAAATGAATAAAGAGATTCCAAATGGAAATACATCAGAGCTTATTTTTAATGCAGTGCATGTAAAAG
ATGCAGGCTTTTATGTCTGTCGAGTTAATAACAATTTCACCTTTGAATTCAGCCAGTGGTCACAGCTGGATGTTTGCGACATCCCAGAGA
GCTTCCAGAGAAGTGTTGATGGCGTCTCTGAATCCAAGTTGCAAATCTGTGTTGAACCAACTTCCCAAAAGCTGATGCCAGGCAGCACAT
TGGTTTTACAGTGTGTTGCTGTTGGAAGCCCTATTCCTCACTACCAGTGGTTCAAAAATGAATTACCATTAACACATGAGACCAAAAAGC
TATACATGGTGCCTTATGTGGATTTGGAACACCAAGGAACCTACTGGTGTCATGTATATAATGATCGAGACAGTCAAGATAGCAAGAAGG
TAGAAATCATCATAGATGAATTAAATAATCTTGGTCATCCTGATAATAAAGAGCAAACAACTGACCAGCCTTTGGCGAAGGACAAGGTTG
CCCTTTTGATAGGAAATATGAATTACCGGGAGCACCCCAAGCTCAAAGCTCCTTTGGTGGATGTGTACGAATTGACTAACTTACTGAGAC
AGCTGGACTTCAAAGTGGTTTCACTGTTGGATCTTACTGAATATGAGATGCGTAATGCTGTGGATGAGTTTTTACTCCTTTTAGACAAGG
GAGTATATGGGTTATTATATTATGCAGGACATGGTTATGAAAATTTTGGGAACAGCTTCATGGTCCCCGTTGATGCTCCAAATCCATATA
GGTCTGAAAATTGTCTGTGTGTACAAAATATACTGAAATTGATGCAAGAAAAAGAAACTGGACTTAATGTGTTCTTATTGGATATGTGTA
GGAAAAGAAATGACTACGATGATACCATTCCAATCTTGGATGCACTAAAAGTCACCGCCAATATTGTGTTTGGATATGCCACGTGTCAAG
GAGCAGAAGCTTTTGAAATCCAGCATTCTGGATTGGCAAATGGAATCTTTATGAAATTTTTAAAAGACAGATTATTAGAAGATAAGAAAA
TCACTGTGTTACTGGATGAAGTTGCAGAAGATATGGGTAAGTGTCACCTTACCAAAGGCAAACAGGCTCTAGAGATTCGAAGTAGTTTAT
CTGAGAAGAGAGCACTTACTGATCCAATACAGGGAACAGAATATTCTGCTGAATCTCTTGTGCGGAATCTACAGTGGGCCAAGGCTCATG
AACTTCCAGAAAGTATGTGTCTTAAGTTTGACTGTGGTGTTCAGATTCAATTAGGATTTGCAGCTGAGTTTTCCAATGTCATGATCATCT
ATACAAGTATAGTTTACAAACCACCGGAGATAATAATGTGTGATGCCTACGTTACTGATTTTCCACTTGATCTAGATATTGATCCAAAAG
ATGCAAATAAAGGCACACCTGAAGAAACTGGCAGCTACTTGGTATCAAAGGATCTTCCCAAGCATTGCCTCTATACCAGACTCAGTTCAC
TGCAAAAATTAAAGGAACATCTAGTCTTCACAGTATGTTTATCATATCAGTACTCAGGATTGGAAGATACTGTAGAGGACAAGCAGGAAG
TGAATGTTGGGAAACCTCTCATTGCTAAATTAGACATGCATCGAGGTTTGGGAAGGAAGACTTGCTTTCAAACTTGTCTTATGTCTAATG
GTCCTTACCAGAGTTCTGCAGCCACCTCAGGAGGAGCAGGGCATTATCACTCATTGCAAGACCCATTCCATGGTGTTTACCATTCACATC
CTGGTAATCCAAGTAATGTTACACCAGCAGATAGCTGTCATTGCAGCCGGACTCCAGATGCATTTATTTCAAGTTTCGCTCACCATGCTT
CATGTCATTTTAGTAGAAGTAATGTGCCAGTAGAGACAACTGATGAAATACCATTTAGTTTCTCTGACAGGCTCAGAATTTCTGAAAAAT
GACCTCCTTGTTTTTGAAAGTTAGCATAATTTTAGATGCCTGTGAAATAGTACTGCACTTACATAAAGTGAGACATTGTGAAAAGGCAAA
TTTGTATATGTAGAGAAAGAATAGTAGTAACTGTTTCATAGCAAACTTCAGGACTTTGAGATGTTGAAATTACATTATTTAATTACAGAC
TTCCTCTTTCTAAGATTTTGTGAATTGGTTGAATAGTTCTATACAAATGAAGTATGGAGGTGTGTATGTTTATATGTATATAACAAAATA

>9744_9744_7_BIRC3-MALT1_BIRC3_chr11_102201973_ENST00000532808_MALT1_chr18_56363598_ENST00000345724_length(amino acids)=1129AA_BP=442
MNIVENSIFLSNLMKSANTFELKYDLSCELYRMSTYSTFPAGVPVSERSLARAGFYYTGVNDKVKCFCCGLMLDNWKRGDSPTEKHKKLY
PSCRFVQSLNSVNNLEATSQPTFPSSVTNSTHSLLPGTENSGYFRGSYSNSPSNPVNSRANQDFSALMRSSYHCAMNNENARLLTFQTWP
LTFLSPTDLAKAGFYYIGPGDRVACFACGGKLSNWEPKDNAMSEHLRHFPKCPFIENQLQDTSRYTVSNLSMQTHAARFKTFFNWPSSVL
VNPEQLASAGFYYVGNSDDVKCFCCDGGLRCWESGDDPWVQHAKWFPRCEYLIRIKGQEFIRQVQASYPHLLEQLLSTSDSPGDENAESS
IIHFEPGEDHSEDAIMMNTPVINAAVEMGFSRSLVKQTVQRKILATGENYRLVNDLVLDLLNAEDEIREEERERATEEKESRIKITVNPE
SKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSELIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSE
SKLQICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHETKKLYMVPYVDLEHQGTYWCHVYNDRDSQDSKKVEIIIDELNNL
GHPDNKEQTTDQPLAKDKVALLIGNMNYREHPKLKAPLVDVYELTNLLRQLDFKVVSLLDLTEYEMRNAVDEFLLLLDKGVYGLLYYAGH
GYENFGNSFMVPVDAPNPYRSENCLCVQNILKLMQEKETGLNVFLLDMCRKRNDYDDTIPILDALKVTANIVFGYATCQGAEAFEIQHSG
LANGIFMKFLKDRLLEDKKITVLLDEVAEDMGKCHLTKGKQALEIRSSLSEKRALTDPIQGTEYSAESLVRNLQWAKAHELPESMCLKFD
CGVQIQLGFAAEFSNVMIIYTSIVYKPPEIIMCDAYVTDFPLDLDIDPKDANKGTPEETGSYLVSKDLPKHCLYTRLSSLQKLKEHLVFT
VCLSYQYSGLEDTVEDKQEVNVGKPLIAKLDMHRGLGRKTCFQTCLMSNGPYQSSAATSGGAGHYHSLQDPFHGVYHSHPGNPSNVTPAD

--------------------------------------------------------------
>9744_9744_8_BIRC3-MALT1_BIRC3_chr11_102201973_ENST00000532808_MALT1_chr18_56363598_ENST00000348428_length(transcript)=5842nt_BP=1446nt
GGGCAGCAGGTTTACAAAGGAGGAAAACGACTTCTTCTAGATTTTTTTTTCAGTTTCTTCTATAAATCAAAACTACCTCCCTAGAGAAAG
GCTAGTCCCTTTTCTTCCCCATTCATTTCATTATGAACATAGTAGAAAACAGCATATTCTTATCAAATTTGATGAAAAGCGCCAACACGT
TTGAACTGAAATACGACTTGTCATGTGAACTGTACCGAATGTCTACGTATTCCACTTTTCCTGCTGGGGTTCCTGTCTCAGAAAGGAGTC
TTGCTCGTGCTGGTTTCTATTACACTGGTGTGAATGACAAGGTCAAATGCTTCTGTTGTGGCCTGATGCTGGATAACTGGAAAAGAGGAG
ACAGTCCTACTGAAAAGCATAAAAAGTTGTATCCTAGCTGCAGATTCGTTCAGAGTCTAAATTCCGTTAACAACTTGGAAGCTACCTCTC
AGCCTACTTTTCCTTCTTCAGTAACAAATTCCACACACTCATTACTTCCGGGTACAGAAAACAGTGGATATTTCCGTGGCTCTTATTCAA
ACTCTCCATCAAATCCTGTAAACTCCAGAGCAAATCAAGATTTTTCTGCCTTGATGAGAAGTTCCTACCACTGTGCAATGAATAACGAAA
ATGCCAGATTACTTACTTTTCAGACATGGCCATTGACTTTTCTGTCGCCAACAGATCTGGCAAAAGCAGGCTTTTACTACATAGGACCTG
GAGACAGAGTGGCTTGCTTTGCCTGTGGTGGAAAATTGAGCAATTGGGAACCGAAGGATAATGCTATGTCAGAACACCTGAGACATTTTC
CCAAATGCCCATTTATAGAAAATCAGCTTCAAGACACTTCAAGATACACAGTTTCTAATCTGAGCATGCAGACACATGCAGCCCGCTTTA
AAACATTCTTTAACTGGCCCTCTAGTGTTCTAGTTAATCCTGAGCAGCTTGCAAGTGCGGGTTTTTATTATGTGGGTAACAGTGATGATG
TCAAATGCTTTTGCTGTGATGGTGGACTCAGGTGTTGGGAATCTGGAGATGATCCATGGGTTCAACATGCCAAGTGGTTTCCAAGGTGTG
AGTACTTGATAAGAATTAAAGGACAGGAGTTCATCCGTCAAGTTCAAGCCAGTTACCCTCATCTACTTGAACAGCTGCTATCCACATCAG
ACAGCCCAGGAGATGAAAATGCAGAGTCATCAATTATCCATTTTGAACCTGGAGAAGACCATTCAGAAGATGCAATCATGATGAATACTC
CTGTGATTAATGCTGCCGTGGAAATGGGCTTTAGTAGAAGCCTGGTAAAACAGACAGTTCAGAGAAAAATCCTAGCAACTGGAGAGAATT
ATAGACTAGTCAATGATCTTGTGTTAGACTTACTCAATGCAGAAGATGAAATAAGGGAAGAGGAGAGAGAAAGAGCAACTGAGGAAAAAG
AATCAAGAATAAAGATTACTGTAAACCCAGAGTCAAAGGCAGTCTTGGCTGGACAGTTTGTGAAACTGTGTTGCCGGGCAACTGGACATC
CTTTTGTTCAATATCAGTGGTTCAAAATGAATAAAGAGATTCCAAATGGAAATACATCAGAGCTTATTTTTAATGCAGTGCATGTAAAAG
ATGCAGGCTTTTATGTCTGTCGAGTTAATAACAATTTCACCTTTGAATTCAGCCAGTGGTCACAGCTGGATGTTTGCGACATCCCAGAGA
GCTTCCAGAGAAGTGTTGATGGCGTCTCTGAATCCAAGTTGCAAATCTGTGTTGAACCAACTTCCCAAAAGCTGATGCCAGGCAGCACAT
TGGTTTTACAGTGTGTTGCTGTTGGAAGCCCTATTCCTCACTACCAGTGGTTCAAAAATGAATTACCATTAACACATGAGACCAAAAAGC
TATACATGGTGCCTTATGTGGATTTGGAACACCAAGGAACCTACTGGTGTCATGTATATAATGATCGAGACAGTCAAGATAGCAAGAAGG
TAGAAATCATCATAGGAAGAACAGATGAGGCAGTGGAGTGCACTGAAGATGAATTAAATAATCTTGGTCATCCTGATAATAAAGAGCAAA
CAACTGACCAGCCTTTGGCGAAGGACAAGGTTGCCCTTTTGATAGGAAATATGAATTACCGGGAGCACCCCAAGCTCAAAGCTCCTTTGG
TGGATGTGTACGAATTGACTAACTTACTGAGACAGCTGGACTTCAAAGTGGTTTCACTGTTGGATCTTACTGAATATGAGATGCGTAATG
CTGTGGATGAGTTTTTACTCCTTTTAGACAAGGGAGTATATGGGTTATTATATTATGCAGGACATGGTTATGAAAATTTTGGGAACAGCT
TCATGGTCCCCGTTGATGCTCCAAATCCATATAGGTCTGAAAATTGTCTGTGTGTACAAAATATACTGAAATTGATGCAAGAAAAAGAAA
CTGGACTTAATGTGTTCTTATTGGATATGTGTAGGAAAAGAAATGACTACGATGATACCATTCCAATCTTGGATGCACTAAAAGTCACCG
CCAATATTGTGTTTGGATATGCCACGTGTCAAGGAGCAGAAGCTTTTGAAATCCAGCATTCTGGATTGGCAAATGGAATCTTTATGAAAT
TTTTAAAAGACAGATTATTAGAAGATAAGAAAATCACTGTGTTACTGGATGAAGTTGCAGAAGATATGGGTAAGTGTCACCTTACCAAAG
GCAAACAGGCTCTAGAGATTCGAAGTAGTTTATCTGAGAAGAGAGCACTTACTGATCCAATACAGGGAACAGAATATTCTGCTGAATCTC
TTGTGCGGAATCTACAGTGGGCCAAGGCTCATGAACTTCCAGAAAGTATGTGTCTTAAGTTTGACTGTGGTGTTCAGATTCAATTAGGAT
TTGCAGCTGAGTTTTCCAATGTCATGATCATCTATACAAGTATAGTTTACAAACCACCGGAGATAATAATGTGTGATGCCTACGTTACTG
ATTTTCCACTTGATCTAGATATTGATCCAAAAGATGCAAATAAAGGCACACCTGAAGAAACTGGCAGCTACTTGGTATCAAAGGATCTTC
CCAAGCATTGCCTCTATACCAGACTCAGTTCACTGCAAAAATTAAAGGAACATCTAGTCTTCACAGTATGTTTATCATATCAGTACTCAG
GATTGGAAGATACTGTAGAGGACAAGCAGGAAGTGAATGTTGGGAAACCTCTCATTGCTAAATTAGACATGCATCGAGGTTTGGGAAGGA
AGACTTGCTTTCAAACTTGTCTTATGTCTAATGGTCCTTACCAGAGTTCTGCAGCCACCTCAGGAGGAGCAGGGCATTATCACTCATTGC
AAGACCCATTCCATGGTGTTTACCATTCACATCCTGGTAATCCAAGTAATGTTACACCAGCAGATAGCTGTCATTGCAGCCGGACTCCAG
ATGCATTTATTTCAAGTTTCGCTCACCATGCTTCATGTCATTTTAGTAGAAGTAATGTGCCAGTAGAGACAACTGATGAAATACCATTTA
GTTTCTCTGACAGGCTCAGAATTTCTGAAAAATGACCTCCTTGTTTTTGAAAGTTAGCATAATTTTAGATGCCTGTGAAATAGTACTGCA
CTTACATAAAGTGAGACATTGTGAAAAGGCAAATTTGTATATGTAGAGAAAGAATAGTAGTAACTGTTTCATAGCAAACTTCAGGACTTT
GAGATGTTGAAATTACATTATTTAATTACAGACTTCCTCTTTCTAAGATTTTGTGAATTGGTTGAATAGTTCTATACAAATGAAGTATGG
AGGTGTGTATGTTTATATGTATATAACAAAATATTTTCATTGTGACCACTCTGAAGTAAGAGCAATGGGAATGGCATTATTGTAGAATAA
GTCATTGTATTTTTAACACCAGAAAGAACCTTGCCGATCACCAGGCATAACCTAATTTTATCCATGGAAGAAACACAGAAAGGCATCTAA
GTTAGAGCTGGCACCAGAACTGAGACCTCCAGAAATCTATTCCAGTATTTTTTCCACTACACAACTGCCTTCCTGACAGGTTCTGAGATA
AGTGTTATGTTTGTAGATAGAGTGAAATATATTTATATATATATAAATATATACAGATACATATCTGTGTATTATCTCAAGGAATGTACA
AACTTTAGTTTTTGATTATAAGGACTTCACTGCAAGTTTTAGTTAAGAGGTTTGTATATAAATCTGTTATAGAACAGGCTGAAATTTCTT
GTTCATAAGATTATGAAACCACATGAGAAGTGATAAAATGTTTGTTAAAGCTAGATAGAGGTTAAGAATCAAGATATAATGGATAATTTT
CATAGCTGCCTATCAGAATTTCCCAAATATTTAGCATCTTCCTTGATAATATGTATTTTCTTCTTGAATTTCACTGGCCTAATGAGATAA
TACTCTTATCTTTGGCTCTACCTAAAAGTTGGTTAAAAATGCAATTGGCATTAACAAGGAAAAATACTGAATTAGTAATTTTAAAAGTCT
CACAAAGAAAATCCCAGGCCTAGATGGCTGCATTGTTGAATTCTGCCAAACATTAAAATTAGCACTAATTTTTTGCACACTGTTTCTAAA
AGTAGGAGAGGAAAGAACACTTCCCAACTTACTCTAGGTCAGTATTACCCTGATACTAGACTAGACATCACAAGAAAACTATAAGCCAAT
ATTCCTTATTAATACAAACACAAAAATCATTAACAAAAATATTAGCAAACTGAATCCAGCAACCTATAAAAAGGATTCTATATCATGACC
AAGTGGAATTTATCCCAGGAATTCAAGGTTGGTTCAACATCTAAAAATCAAATAAGCTAATATACAGTCAGTTCTCATTATTCACAGTAA
TTATGTTCTACAGAATATTCTCCCATAAACACTGAATTAAATATGGAACAACTGCTTTTAGGAGAAAGTGTATTTGTGTATATGTGTGTA
TACATATGTTTATCTCACACACATTATGAGCTTGAATTCTTAATTCATCCTAGCAAATTCTACCTTATTTTACAGAAGTGAAAGTGAGGT
ATCAGAAGTGTTAAGTGACATGCCTGAGGCACCCCCCTAACAGGTGTCAGAGCTGAAATTCAAACCCCATCCAGCTGGCCCCGGAGCCAG
AGCTTCTTGTACTACACAGAATTGCCCCTGCCATTTCCACCCTCCAGTCATTTCTCTATGAGACTGAAGCAGGAAGGCAGAGCATCATCT
TGTTCAGCCTCAGCTGGGAACATGTGTACTGGGTGACTCAAATTTTTCACCCATTTACACATATCCACAAATGACTGCAAAAGTGCCACG
GATATCAATTTGAGGGTTATAAATTTTAGCAAGTTGGTAAATTCACAAATACATAACCTTGAATAATGAGGATCAACTGTACCATATTTA
ATAAAGCACAAAACCCACACAGATTGTCTTATTACAGCATTTGATAAAATCCAAAACTCTTTCATAAAAACACTCAACAAACTTAGGAAT
AAAAGGAATCTTCCTAGATATGATAAATATAACATCTATGAAAAGCCCACACCTAACATTATACTTCATGGTGATAGACTGAAGGCTGAA
TGTTTTCCCCTTAAGATTGGGAAGAAGGACAAGGATGTTCACTCGGCACTACTTCTATTCAGCATTGTACTTGAAGTTCTAGCCACAGCA
GTTAGGTTAGGAATTCAAGGTTTGTTCAACATCTAAAAATCAAATAAGCTAATAAAGAAAAGAGGTTTATACTGCAAAAGAAGTGAAACT

>9744_9744_8_BIRC3-MALT1_BIRC3_chr11_102201973_ENST00000532808_MALT1_chr18_56363598_ENST00000348428_length(amino acids)=1140AA_BP=442
MNIVENSIFLSNLMKSANTFELKYDLSCELYRMSTYSTFPAGVPVSERSLARAGFYYTGVNDKVKCFCCGLMLDNWKRGDSPTEKHKKLY
PSCRFVQSLNSVNNLEATSQPTFPSSVTNSTHSLLPGTENSGYFRGSYSNSPSNPVNSRANQDFSALMRSSYHCAMNNENARLLTFQTWP
LTFLSPTDLAKAGFYYIGPGDRVACFACGGKLSNWEPKDNAMSEHLRHFPKCPFIENQLQDTSRYTVSNLSMQTHAARFKTFFNWPSSVL
VNPEQLASAGFYYVGNSDDVKCFCCDGGLRCWESGDDPWVQHAKWFPRCEYLIRIKGQEFIRQVQASYPHLLEQLLSTSDSPGDENAESS
IIHFEPGEDHSEDAIMMNTPVINAAVEMGFSRSLVKQTVQRKILATGENYRLVNDLVLDLLNAEDEIREEERERATEEKESRIKITVNPE
SKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSELIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSE
SKLQICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHETKKLYMVPYVDLEHQGTYWCHVYNDRDSQDSKKVEIIIGRTDEA
VECTEDELNNLGHPDNKEQTTDQPLAKDKVALLIGNMNYREHPKLKAPLVDVYELTNLLRQLDFKVVSLLDLTEYEMRNAVDEFLLLLDK
GVYGLLYYAGHGYENFGNSFMVPVDAPNPYRSENCLCVQNILKLMQEKETGLNVFLLDMCRKRNDYDDTIPILDALKVTANIVFGYATCQ
GAEAFEIQHSGLANGIFMKFLKDRLLEDKKITVLLDEVAEDMGKCHLTKGKQALEIRSSLSEKRALTDPIQGTEYSAESLVRNLQWAKAH
ELPESMCLKFDCGVQIQLGFAAEFSNVMIIYTSIVYKPPEIIMCDAYVTDFPLDLDIDPKDANKGTPEETGSYLVSKDLPKHCLYTRLSS
LQKLKEHLVFTVCLSYQYSGLEDTVEDKQEVNVGKPLIAKLDMHRGLGRKTCFQTCLMSNGPYQSSAATSGGAGHYHSLQDPFHGVYHSH

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Fusion Gene PPI Analysis for BIRC3-MALT1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for BIRC3-MALT1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for BIRC3-MALT1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource