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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:UTY-KDM6A (FusionGDB2 ID:97776)

Fusion Gene Summary for UTY-KDM6A

Fusion gene summary

Fusion gene information	Fusion gene name: UTY-KDM6A
	Fusion gene ID: 97776
		Hgene	Tgene
	Gene symbol	UTY	KDM6A
	Gene ID	7404	7403
	Gene name	ubiquitously transcribed tetratricopeptide repeat containing, Y-linked	lysine demethylase 6A
	Synonyms	KDM6AL\|KDM6C\|UTY1	KABUK2\|UTX\|bA386N14.2
	Cytomap	Yq11.221	Xp11.3
	Type of gene	protein-coding	protein-coding
	Description	histone demethylase UTYubiquitous TPR motif protein UTYubiquitously transcribed TPR gene on Y chromosomeubiquitously transcribed tetratricopeptide repeat gene, Y chromosomeubiquitously transcribed tetratricopeptide repeat gene, Y-linkedubiquitously-t	lysine-specific demethylase 6AbA386N14.2 (ubiquitously transcribed X chromosome tetratricopeptide repeat protein (UTX))histone demethylase UTXlysine (K)-specific demethylase 6Aubiquitously transcribed tetratricopeptide repeat protein X-linkedubiquito
	Modification date	20200313	20200313
	UniProtAcc	.	O15550
	Ensembl transtripts involved in fusion gene	ENST00000540140, ENST00000545955, ENST00000329134, ENST00000331397, ENST00000362096, ENST00000382893, ENST00000382896, ENST00000474365, ENST00000537580, ENST00000538878,	ENST00000479423, ENST00000377967, ENST00000382899, ENST00000536777, ENST00000543216,
Fusion gene scores	* DoF score	5 X 6 X 2=60	13 X 15 X 6=1170
	# samples	6	16
	** MAII score	log2(6/60*10)=0	log2(16/1170*10)=-2.8703647195834 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: UTY [Title/Abstract] AND KDM6A [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	UTY(15470343)-KDM6A(44920568), # samples:74
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Fusion gene breakpoints across UTY (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across KDM6A (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	Non-Cancer	115Nd	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	117Nd	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	119Nd	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	123Nd	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	13N	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	143N	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	145N	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	201N	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	203N	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	235N	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	265N	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	269N	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	271N	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	43N	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	5263N	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	5357N	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	61N	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-22-5482-11A	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-22-5489-11A	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-43-3394-11A	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-43-5670-11A	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-43-7657-11A	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-43-7658-11A	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-44-6146-11A	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-51-4079-11A	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-51-4080-11A	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-55-6986-11A	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-77-7337-11A	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-AF-2692-11A	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-AF-3400-11A	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-AG-3742-11A	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-B9-4115-11A	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-BH-A0AZ-11A	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-BH-A0B3-11B	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-BH-A0BV-11A	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-BH-A0DV-11A	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-BH-A1EW-11B	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-BQ-5878-11A	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-BR-6453-11A	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-BR-6852-11A	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-BR-7851-11A	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-BR-8060-11A	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-CG-5722-11A	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-CH-5767-11B	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-CV-6933-11A	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-CV-6938-11A	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-CV-7235-11A	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-CV-7255-11A	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-E2-A1LS-11A	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-EJ-7782-11A	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-EJ-7786-11A	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-EJ-7792-11A	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-EJ-7797-11A	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-EL-A3ZR-11A	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-EM-A1CT-11A	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-GL-A9DE-11A	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-H6-8124-11A	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-H7-A6C5-11A	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-HU-8238-11A	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-IC-A6RE-11A	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-IC-A6RF-11A	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-IG-A3I8-11A	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-IN-8462-11A	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-IN-AB1V-11A	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-IN-AB1X-11A	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-IP-7968-11A	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-L5-A43C-11A	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-L5-A4OF-11A	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-L5-A4OG-11A	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-L5-A4OJ-11A	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-L5-A4OM-11A	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-L5-A4OO-11A	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-L5-A4OQ-11A	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
ChimerDB4	Non-Cancer	TCGA-V5-AASX-11A	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+

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Fusion Gene ORF analysis for UTY-KDM6A

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-intron	ENST00000540140	ENST00000479423	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
5CDS-intron	ENST00000545955	ENST00000479423	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
In-frame	ENST00000540140	ENST00000377967	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
In-frame	ENST00000540140	ENST00000382899	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
In-frame	ENST00000540140	ENST00000536777	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
In-frame	ENST00000540140	ENST00000543216	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
In-frame	ENST00000545955	ENST00000377967	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
In-frame	ENST00000545955	ENST00000382899	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
In-frame	ENST00000545955	ENST00000536777	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
In-frame	ENST00000545955	ENST00000543216	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
intron-3CDS	ENST00000329134	ENST00000377967	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
intron-3CDS	ENST00000329134	ENST00000382899	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
intron-3CDS	ENST00000329134	ENST00000536777	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
intron-3CDS	ENST00000329134	ENST00000543216	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
intron-3CDS	ENST00000331397	ENST00000377967	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
intron-3CDS	ENST00000331397	ENST00000382899	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
intron-3CDS	ENST00000331397	ENST00000536777	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
intron-3CDS	ENST00000331397	ENST00000543216	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
intron-3CDS	ENST00000362096	ENST00000377967	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
intron-3CDS	ENST00000362096	ENST00000382899	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
intron-3CDS	ENST00000362096	ENST00000536777	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
intron-3CDS	ENST00000362096	ENST00000543216	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
intron-3CDS	ENST00000382893	ENST00000377967	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
intron-3CDS	ENST00000382893	ENST00000382899	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
intron-3CDS	ENST00000382893	ENST00000536777	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
intron-3CDS	ENST00000382893	ENST00000543216	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
intron-3CDS	ENST00000382896	ENST00000377967	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
intron-3CDS	ENST00000382896	ENST00000382899	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
intron-3CDS	ENST00000382896	ENST00000536777	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
intron-3CDS	ENST00000382896	ENST00000543216	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
intron-3CDS	ENST00000474365	ENST00000377967	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
intron-3CDS	ENST00000474365	ENST00000382899	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
intron-3CDS	ENST00000474365	ENST00000536777	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
intron-3CDS	ENST00000474365	ENST00000543216	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
intron-3CDS	ENST00000537580	ENST00000377967	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
intron-3CDS	ENST00000537580	ENST00000382899	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
intron-3CDS	ENST00000537580	ENST00000536777	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
intron-3CDS	ENST00000537580	ENST00000543216	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
intron-3CDS	ENST00000538878	ENST00000377967	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
intron-3CDS	ENST00000538878	ENST00000382899	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
intron-3CDS	ENST00000538878	ENST00000536777	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
intron-3CDS	ENST00000538878	ENST00000543216	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
intron-intron	ENST00000329134	ENST00000479423	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
intron-intron	ENST00000331397	ENST00000479423	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
intron-intron	ENST00000362096	ENST00000479423	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
intron-intron	ENST00000382893	ENST00000479423	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
intron-intron	ENST00000382896	ENST00000479423	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
intron-intron	ENST00000474365	ENST00000479423	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
intron-intron	ENST00000537580	ENST00000479423	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+
intron-intron	ENST00000538878	ENST00000479423	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000540140	UTY	chrY	15470343	-	ENST00000377967	KDM6A	chrX	44920568	+	5244	1176	0	4052	1350
ENST00000540140	UTY	chrY	15470343	-	ENST00000382899	KDM6A	chrX	44920568	+	4146	1176	0	4052	1350
ENST00000540140	UTY	chrY	15470343	-	ENST00000536777	KDM6A	chrX	44920568	+	4150	1176	0	4052	1350
ENST00000540140	UTY	chrY	15470343	-	ENST00000543216	KDM6A	chrX	44920568	+	3951	1176	0	3950	1316
ENST00000545955	UTY	chrY	15470343	-	ENST00000377967	KDM6A	chrX	44920568	+	5478	1410	0	4286	1428
ENST00000545955	UTY	chrY	15470343	-	ENST00000382899	KDM6A	chrX	44920568	+	4380	1410	0	4286	1428
ENST00000545955	UTY	chrY	15470343	-	ENST00000536777	KDM6A	chrX	44920568	+	4384	1410	0	4286	1428
ENST00000545955	UTY	chrY	15470343	-	ENST00000543216	KDM6A	chrX	44920568	+	4185	1410	0	4184	1394

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000540140	ENST00000377967	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+	8.69E-05	0.9999131
ENST00000540140	ENST00000382899	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+	0.000333745	0.9996662
ENST00000540140	ENST00000536777	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+	0.000336646	0.99966335
ENST00000540140	ENST00000543216	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+	0.00083166	0.9991684
ENST00000545955	ENST00000377967	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+	0.000100963	0.999899
ENST00000545955	ENST00000382899	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+	0.000390477	0.99960953
ENST00000545955	ENST00000536777	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+	0.000393498	0.99960655
ENST00000545955	ENST00000543216	UTY	chrY	15470343	-	KDM6A	chrX	44920568	+	0.000625439	0.99937457

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Fusion Genomic Features for UTY-KDM6A

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
UTY	chrY	15470343	-	KDM6A	chrX	44920568	+	2.57E-07	0.99999976
UTY	chrY	15470343	-	KDM6A	chrX	44920568	+	2.57E-07	0.99999976

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for UTY-KDM6A

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chrY:15470343/chrX:44920568)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	KDM6A O15550
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code (PubMed:17851529, PubMed:17713478, PubMed:17761849). Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-27' (PubMed:17851529, PubMed:17713478, PubMed:17761849). Plays a central role in regulation of posterior development, by regulating HOX gene expression (PubMed:17851529). Demethylation of 'Lys-27' of histone H3 is concomitant with methylation of 'Lys-4' of histone H3, and regulates the recruitment of the PRC1 complex and monoubiquitination of histone H2A (PubMed:17761849). Plays a demethylase-independent role in chromatin remodeling to regulate T-box family member-dependent gene expression (By similarity). {ECO:0000250\|UniProtKB:O70546, ECO:0000269\|PubMed:17713478, ECO:0000269\|PubMed:17761849, ECO:0000269\|PubMed:17851529, ECO:0000269\|PubMed:18003914}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

KDM6A

chrY:15470343

chrX:44920568

ENST00000377967

1095_1258

443

1402.0

Domain

JmjC

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

UTY

chrY:15470343

chrX:44920568

ENST00000329134

1042_1205

1080.0

Domain

JmjC

Hgene

UTY

chrY:15470343

chrX:44920568

ENST00000331397

1042_1205

1348.0

Domain

JmjC

Hgene

UTY

chrY:15470343

chrX:44920568

ENST00000362096

1042_1205

1241.0

Domain

JmjC

Hgene

UTY

chrY:15470343

chrX:44920568

ENST00000382896

1042_1205

1393.0

Domain

JmjC

Hgene

UTY

chrY:15470343

chrX:44920568

ENST00000537580

1042_1205

1212.0

Domain

JmjC

Hgene

UTY

chrY:15470343

chrX:44920568

ENST00000329134

127_160

1080.0

Repeat

Note=TPR 2

Hgene

UTY

chrY:15470343

chrX:44920568

ENST00000329134

167_196

1080.0

Repeat

Note=TPR 3

Hgene

UTY

chrY:15470343

chrX:44920568

ENST00000329134

202_235

1080.0

Repeat

Note=TPR 4

Hgene

UTY

chrY:15470343

chrX:44920568

ENST00000329134

247_280

1080.0

Repeat

Note=TPR 5

Hgene

UTY

chrY:15470343

chrX:44920568

ENST00000329134

281_314

1080.0

Repeat

Note=TPR 6

Hgene

UTY

chrY:15470343

chrX:44920568

ENST00000329134

315_348

1080.0

Repeat

Note=TPR 7

Hgene

UTY

chrY:15470343

chrX:44920568

ENST00000329134

349_382

1080.0

Repeat

Note=TPR 8

Hgene

UTY

chrY:15470343

chrX:44920568

ENST00000329134

90_123

1080.0

Repeat

Note=TPR 1

Hgene

UTY

chrY:15470343

chrX:44920568

ENST00000331397

127_160

1348.0

Repeat

Note=TPR 2

Hgene

UTY

chrY:15470343

chrX:44920568

ENST00000331397

167_196

1348.0

Repeat

Note=TPR 3

Hgene

UTY

chrY:15470343

chrX:44920568

ENST00000331397

202_235

1348.0

Repeat

Note=TPR 4

Hgene

UTY

chrY:15470343

chrX:44920568

ENST00000331397

247_280

1348.0

Repeat

Note=TPR 5

Hgene

UTY

chrY:15470343

chrX:44920568

ENST00000331397

281_314

1348.0

Repeat

Note=TPR 6

Hgene

UTY

chrY:15470343

chrX:44920568

ENST00000331397

315_348

1348.0

Repeat

Note=TPR 7

Hgene

UTY

chrY:15470343

chrX:44920568

ENST00000331397

349_382

1348.0

Repeat

Note=TPR 8

Hgene

UTY

chrY:15470343

chrX:44920568

ENST00000331397

90_123

1348.0

Repeat

Note=TPR 1

Hgene

UTY

chrY:15470343

chrX:44920568

ENST00000362096

127_160

1241.0

Repeat

Note=TPR 2

Hgene

UTY

chrY:15470343

chrX:44920568

ENST00000362096

167_196

1241.0

Repeat

Note=TPR 3

Hgene

UTY

chrY:15470343

chrX:44920568

ENST00000362096

202_235

1241.0

Repeat

Note=TPR 4

Hgene

UTY

chrY:15470343

chrX:44920568

ENST00000362096

247_280

1241.0

Repeat

Note=TPR 5

Hgene

UTY

chrY:15470343

chrX:44920568

ENST00000362096

281_314

1241.0

Repeat

Note=TPR 6

Hgene

UTY

chrY:15470343

chrX:44920568

ENST00000362096

315_348

1241.0

Repeat

Note=TPR 7

Hgene

UTY

chrY:15470343

chrX:44920568

ENST00000362096

349_382

1241.0

Repeat

Note=TPR 8

Hgene

UTY

chrY:15470343

chrX:44920568

ENST00000362096

90_123

1241.0

Repeat

Note=TPR 1

Hgene

UTY

chrY:15470343

chrX:44920568

ENST00000382896

127_160

1393.0

Repeat

Note=TPR 2

Hgene

UTY

chrY:15470343

chrX:44920568

ENST00000382896

167_196

1393.0

Repeat

Note=TPR 3

Hgene

UTY

chrY:15470343

chrX:44920568

ENST00000382896

202_235

1393.0

Repeat

Note=TPR 4

Hgene

UTY

chrY:15470343

chrX:44920568

ENST00000382896

247_280

1393.0

Repeat

Note=TPR 5

Hgene

UTY

chrY:15470343

chrX:44920568

ENST00000382896

281_314

1393.0

Repeat

Note=TPR 6

Hgene

UTY

chrY:15470343

chrX:44920568

ENST00000382896

315_348

1393.0

Repeat

Note=TPR 7

Hgene

UTY

chrY:15470343

chrX:44920568

ENST00000382896

349_382

1393.0

Repeat

Note=TPR 8

Hgene

UTY

chrY:15470343

chrX:44920568

ENST00000382896

90_123

1393.0

Repeat

Note=TPR 1

Hgene

UTY

chrY:15470343

chrX:44920568

ENST00000537580

127_160

1212.0

Repeat

Note=TPR 2

Hgene

UTY

chrY:15470343

chrX:44920568

ENST00000537580

167_196

1212.0

Repeat

Note=TPR 3

Hgene

UTY

chrY:15470343

chrX:44920568

ENST00000537580

202_235

1212.0

Repeat

Note=TPR 4

Hgene

UTY

chrY:15470343

chrX:44920568

ENST00000537580

247_280

1212.0

Repeat

Note=TPR 5

Hgene

UTY

chrY:15470343

chrX:44920568

ENST00000537580

281_314

1212.0

Repeat

Note=TPR 6

Hgene

UTY

chrY:15470343

chrX:44920568

ENST00000537580

315_348

1212.0

Repeat

Note=TPR 7

Hgene

UTY

chrY:15470343

chrX:44920568

ENST00000537580

349_382

1212.0

Repeat

Note=TPR 8

Hgene

UTY

chrY:15470343

chrX:44920568

ENST00000537580

90_123

1212.0

Repeat

Note=TPR 1

Tgene

KDM6A

chrY:15470343

chrX:44920568

ENST00000377967

9_17

443

1402.0

Compositional bias

Note=Poly-Ala

Tgene

KDM6A

chrY:15470343

chrX:44920568

ENST00000377967

130_163

443

1402.0

Repeat

Note=TPR 2

Tgene

KDM6A

chrY:15470343

chrX:44920568

ENST00000377967

170_199

443

1402.0

Repeat

Note=TPR 3

Tgene

KDM6A

chrY:15470343

chrX:44920568

ENST00000377967

205_238

443

1402.0

Repeat

Note=TPR 4

Tgene

KDM6A

chrY:15470343

chrX:44920568

ENST00000377967

250_283

443

1402.0

Repeat

Note=TPR 5

Tgene

KDM6A

chrY:15470343

chrX:44920568

ENST00000377967

284_317

443

1402.0

Repeat

Note=TPR 6

Tgene

KDM6A

chrY:15470343

chrX:44920568

ENST00000377967

318_351

443

1402.0

Repeat

Note=TPR 7

Tgene

KDM6A

chrY:15470343

chrX:44920568

ENST00000377967

352_385

443

1402.0

Repeat

Note=TPR 8

Tgene

KDM6A

chrY:15470343

chrX:44920568

ENST00000377967

93_126

443

1402.0

Repeat

Note=TPR 1

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Fusion Gene Sequence for UTY-KDM6A

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>97776_97776_1_UTY-KDM6A_UTY_chrY_15470343_ENST00000540140_KDM6A_chrX_44920568_ENST00000377967_length(transcript)=5244nt_BP=1176nt
ATGAAATCCTGCGCAGTGTCGCTCACTACCGCCGCTGTTGCCTTCGGTGATGAGGCAAAGAAAATGGCGGAAGGAAAAGCGAGCCGCGAG
AGTGAAGAGGAGTCTGTTAGCCTGACAGTCGAGGAAAGGGAGGCGCTTGGTGGCATGGACAGCCGTCTCTTCGGGTTCGTGAGGCTTCAT
GAAGATGGCGCCAGAACGAAGACCCTACTAGGCAAGGCTGTTCGCTGCTACGAATCTTTAATCTTAAAAGCTGAAGGAAAAGTGGAGTCT
GACTTCTTTTGCCAATTAGGTCACTTCAACCTCTTGTTGGAAGATTATTCAAAAGCATTATCTGCATATCAGAGATATTACAGTTTACAG
GCTGACTACTGGAAGAATGCTGCGTTTTTATATGGCCTTGGTTTGGTCTACTTCTACTACAATGCATTTCATTGGGCAATTAAAGCATTT
CAAGATGTCCTTTATGTTGACCCCAGCTTTTGTCGAGCCAAGGAAATTCATTTACGACTTGGGCTCATGTTCAAAGTGAACACAGACTAC
AAGTCTAGTTTAAAGCATTTTCAGTTAGCCTTGATTGACTGTAATCCATGTACTTTGTCCAATGCTGAAATTCAATTTCATATTGCCCAT
TTGTATGAAACCCAGAGGAAGTATCATTCTGCAAAGGAGGCATATGAACAACTTTTGCAGACAGAAAACCTTCCTGCACAAGTAAAAGCA
ACTGTATTGCAACAGTTAGGTTGGATGCATCATAATATGGATCTAGTAGGAGACAAAGCCACAAAGGAAAGCTATGCTATTCAGTATCTC
CAAAAGTCTTTGGAGGCAGATCCTAATTCTGGCCAATCGTGGTATTTTCTTGGAAGTGTGTTGTATCAGCAGCAAAATCAGCCTATGGAT
GCTTTACAGGCATATATTTGTGCTGTACAATTGGACCATGGGCATGCCGCAGCCTGGATGGACCTAGGTACTCTCTATGAATCCTGCAAT
CAACCTCAAGATGCCATTAAATGCTACCTAAATGCAGCTAGAAGCAAACGTTGTAGTAATACCTCTACGCTTGCTGCAAGAATTAAATTT
CTACAGCAATCCTTGTCACTACACATGATTACTTCTAGCCAAGTAGAAGGCCTGTCCAGTCCTGCCAAGAAGAAAAGAACATCTAGTCCA
ACAAAGAATACTTCTGACAATTGGAGTGGTGGACATGCTGTGTCACATCCTCCAGTACAGCAACAAGCTCATTCATGGTGTTTGACACCA
CAGAAATTACAGCATTTGGAACAGCTCCGCGCAAATAGAAATAATTTAAATCCAGCACAGAAACTGATGCTGGAACAGCTGGAAAGTCAG
TTTGTCTTAATGCAACAACACCAAATGAGACCAACAGGAGTTGCACAGGTACGATCTACTGGAATTCCTAATGGGCCAACAGCTGACTCA
TCACTGCCTACAAACTCAGTCTCTGGCCAGCAGCCACAGCTTGCTCTGACCAGAGTGCCTAGCGTCTCTCAGCCTGGAGTCCGTCCTGCC
TGCCCTGGGCAGCCTTTGGCCAATGGACCCTTTTCTGCAGGCCATGTTCCCTGTAGCACATCAAGAACGCTGGGAAGTACAGACACTATT
TTGATAGGCAATAATCATATAACAGGAAGTGGAAGTAATGGAAACGTGCCTTACCTGCAGCGAAACGCACTCACTCTACCTCATAACCGC
ACAAACCTGACCAGCAGCGCAGAGGAGCCGTGGAAAAACCAACTATCTAACTCCACTCAGGGGCTTCACAAAGGTCAGAGTTCACATTCG
GCAGGTCCTAATGGTGAACGACCTCTCTCTTCCACTGGGCCTTCCCAGCATCTCCAGGCAGCTGGCTCTGGTATTCAGAATCAGAACGGA
CATCCCACCCTGCCTAGCAATTCAGTAACACAGGGGGCTGCTCTCAATCACCTCTCCTCTCACACTGCTACCTCAGGTGGACAACAAGGC
ATTACCTTAACCAAAGAGAGCAAGCCTTCAGGAAACATATTGACGGTGCCTGAAACAAGCAGGCACACTGGAGAGACACCTAACAGCACT
GCCAGTGTCGAGGGACTTCCTAATCATGTCCATCAGATGACGGCAGATGCTGTTTGCAGTCCTAGCCATGGAGATTCTAAGTCACCAGGT
TTACTAAGTTCAGACAATCCTCAGCTCTCTGCCTTGTTGATGGGAAAAGCCAATAACAATGTGGGTACTGGAACCTGTGACAAAGTCAAT
AACATCCACCCAGCTGTTCATACAAAGACTGATAACTCTGTTGCCTCTTCACCATCTTCAGCCATTTCAACAGCAACACCTTCTCCAAAA
TCCACTGAGCAGACAACCACAAACAGTGTTACCAGCCTTAACAGCCCTCACAGTGGGCTACACACAATTAATGGAGAAGGGATGGAAGAA
TCTCAGAGCCCCATGAAAACAGATCTGCTTCTGGTTAACCACAAACCTAGTCCACAGATCATACCATCAATGTCTGTGTCCATATACCCC
AGCTCAGCAGAAGTTCTGAAGGCATGCAGGAATCTAGGTAAAAATGGCTTATCTAACAGTAGCATTTTGTTGGATAAATGTCCACCTCCA
AGACCACCATCTTCACCATACCCTCCCTTGCCAAAGGACAAGTTGAATCCACCTACACCTAGTATTTACTTGGAAAATAAACGTGATGCT
TTCTTTCCTCCATTACATCAATTTTGTACAAATCCGAACAACCCTGTTACAGTAATACGTGGCCTTGCTGGAGCTCTTAAGTTAGACCTG
GGACTTTTCTCTACTAAAACTTTGGTGGAAGCTAACAATGAACATATGGTAGAAGTGAGGACACAGTTGTTGCAGCCAGCAGATGAAAAC
TGGGATCCCACTGGAACAAAGAAAATCTGGCATTGTGAAAGTAATAGATCTCATACTACAATTGCTAAATATGCACAGTACCAGGCCTCC
TCATTCCAGGAATCATTGAGAGAAGAAAATGAAAAAAGAAGTCATCATAAAGACCACTCAGATAGTGAATCTACATCGTCAGATAATTCT
GGGAGGAGGAGGAAAGGACCCTTTAAAACCATAAAGTTTGGGACCAATATTGACCTATCTGATGACAAAAAGTGGAAGTTGCAGCTACAT
GAGCTGACTAAACTTCCTGCTTTTGTGCGTGTCGTATCAGCAGGAAATCTTCTAAGCCATGTTGGTCATACCATATTGGGCATGAACACA
GTTCAACTATACATGAAAGTTCCAGGGAGCAGAACACCAGGTCATCAGGAAAATAACAACTTCTGTTCAGTTAACATAAATATTGGCCCA
GGTGACTGTGAATGGTTTGTTGTTCCTGAAGGTTACTGGGGTGTTCTGAATGACTTCTGTGAAAAAAATAATTTGAATTTCCTAATGGGT
TCTTGGTGGCCCAATCTTGAAGATCTTTATGAAGCAAATGTTCCAGTGTATAGGTTTATTCAGCGACCTGGAGATTTGGTCTGGATAAAT
GCAGGCACTGTTCATTGGGTTCAGGCTATTGGCTGGTGCAACAACATTGCTTGGAATGTTGGTCCACTTACAGCCTGCCAGTATAAATTG
GCAGTGGAACGGTACGAATGGAACAAATTGCAAAGTGTGAAGTCAATAGTACCCATGGTTCATCTTTCCTGGAATATGGCACGAAATATC
AAGGTCTCAGATCCAAAGCTTTTTGAAATGATTAAGTATTGTCTTCTAAGAACTCTGAAGCAATGTCAGACATTGAGGGAAGCTCTCATT
GCTGCAGGAAAAGAGATTATATGGCATGGGCGGACAAAAGAAGAACCAGCTCATTACTGTAGCATTTGTGAAGTGGAGGTTTTTGATCTG
CTTTTTGTCACTAATGAGAGTAATTCACGAAAGACCTACATAGTACATTGCCAAGATTGTGCACGAAAAACAAGCGGAAACTTGGAAAAC
TTTGTGGTGCTAGAACAGTACAAAATGGAGGACCTGATGCAAGTCTATGACCAATTTACATTAGCTCCTCCATTACCATCCGCCTCATCT
TGATATTGTTCCATGGACATTAAATGAGACCTTTTCTGCTATTCAGGAAATAACCCAGTTCTGCACCACTGGTTTTTGTAGCTATCTCGT
AAGGCTGCTGGCTGAAAACTGTGTCTATGCAACCTTCCAAGTGCGGAGTGTCAACCAACTGGACGGGAGAGAGTACTGCTCCTACTCCAG
GACTCTCACAAAGCTGATGAGCTGTACTTCAGAAAAAAATAATAATTTCCATGTTTTGTATATATCTGACAAAACTGGCAACATCTTACA
GACTACTGACTTGAAGACAACCTCTTTTATATTTCTCTATTTCTGGGCTGATGAATTTGTTTTCATCTGTCTTTTCCCCCTTCAGAATTT
TCCTTGGAAAAAAAATACTAGCCTAGCTGGTCATTTCTTTGTAAGGTAGTTAGCAATTTTAAGTCTTTCTTTGGTCAACTTTTTTTTAAT
GTGAAAAGTTAGGTAAGACACTTTTTTACTGCTTTTATGTTTTTCTGTCTTGTTTTGAGACCATGATGGTTACACTTTTGGTTCCTAAAT
AAAATTTAAAAAATTAACAGCCAAGTCACAAAGGTAATGGATTGCACATAGACTAAGGAATAAACTTCAGATTTGTGATTTTTGTTTCTA
ATCTTGATGTAAATTTACACTATTTATAAATACATATTTATTGCTTGAAAATATTTGTGAATGGAATGCTGTTATTTTTTCCAGATTTAC
CTGCCATTGAAATTTTAAGGAGTTCTGTAATTTCAAACACTACTCCTATTACATTTTCTATGTGTAAATAAAACTGCTTAGCATTGTACA
GAAACTTTTATTAAAATTGTTTAATGTTTAAAGAGTTTTCTATTGTTTGAGTTTTAAAAAAGACTTTATGTACAGTGCCCAGTTTTTGTT
CATTTTTGAAATCTGATTATATATATTTTATATATACTTATGTATGTATATATAATATATATAGAAATCTGGATATATATGTATAAATCT
TTAGAACTTAAATTTTTCTCGTTTTAAGTTTCACATCTATGGTAGATTTTTGAGGTGTCTACTGTAAAGTATTGCTTACAAAAAGTATGA
TTATTTTTAAAGAAATATATATGGTATGTATCCTCAAGACCTAAAATGTCAGACTGGTTTATTGTTAAGTTGCAATTACTGCAATGACAG

>97776_97776_1_UTY-KDM6A_UTY_chrY_15470343_ENST00000540140_KDM6A_chrX_44920568_ENST00000377967_length(amino acids)=1350AA_BP=10
MKSCAVSLTTAAVAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFVRLHEDGARTKTLLGKAVRCYESLILKAEGKVES
DFFCQLGHFNLLLEDYSKALSAYQRYYSLQADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDY
KSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKATVLQQLGWMHHNMDLVGDKATKESYAIQYL
QKSLEADPNSGQSWYFLGSVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNAARSKRCSNTSTLAARIKF
LQQSLSLHMITSSQVEGLSSPAKKKRTSSPTKNTSDNWSGGHAVSHPPVQQQAHSWCLTPQKLQHLEQLRANRNNLNPAQKLMLEQLESQ
FVLMQQHQMRPTGVAQVRSTGIPNGPTADSSLPTNSVSGQQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTLGSTDTI
LIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQSSHSAGPNGERPLSSTGPSQHLQAAGSGIQNQNG
HPTLPSNSVTQGAALNHLSSHTATSGGQQGITLTKESKPSGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSPG
LLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPKSTEQTTTNSVTSLNSPHSGLHTINGEGMEE
SQSPMKTDLLLVNHKPSPQIIPSMSVSIYPSSAEVLKACRNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTPSIYLENKRDA
FFPPLHQFCTNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKIWHCESNRSHTTIAKYAQYQAS
SFQESLREENEKRSHHKDHSDSESTSSDNSGRRRKGPFKTIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHTILGMNT
VQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFCEKNNLNFLMGSWWPNLEDLYEANVPVYRFIQRPGDLVWIN
AGTVHWVQAIGWCNNIAWNVGPLTACQYKLAVERYEWNKLQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIKYCLLRTLKQCQTLREALI
AAGKEIIWHGRTKEEPAHYCSICEVEVFDLLFVTNESNSRKTYIVHCQDCARKTSGNLENFVVLEQYKMEDLMQVYDQFTLAPPLPSASS

--------------------------------------------------------------
>97776_97776_2_UTY-KDM6A_UTY_chrY_15470343_ENST00000540140_KDM6A_chrX_44920568_ENST00000382899_length(transcript)=4146nt_BP=1176nt
ATGAAATCCTGCGCAGTGTCGCTCACTACCGCCGCTGTTGCCTTCGGTGATGAGGCAAAGAAAATGGCGGAAGGAAAAGCGAGCCGCGAG
AGTGAAGAGGAGTCTGTTAGCCTGACAGTCGAGGAAAGGGAGGCGCTTGGTGGCATGGACAGCCGTCTCTTCGGGTTCGTGAGGCTTCAT
GAAGATGGCGCCAGAACGAAGACCCTACTAGGCAAGGCTGTTCGCTGCTACGAATCTTTAATCTTAAAAGCTGAAGGAAAAGTGGAGTCT
GACTTCTTTTGCCAATTAGGTCACTTCAACCTCTTGTTGGAAGATTATTCAAAAGCATTATCTGCATATCAGAGATATTACAGTTTACAG
GCTGACTACTGGAAGAATGCTGCGTTTTTATATGGCCTTGGTTTGGTCTACTTCTACTACAATGCATTTCATTGGGCAATTAAAGCATTT
CAAGATGTCCTTTATGTTGACCCCAGCTTTTGTCGAGCCAAGGAAATTCATTTACGACTTGGGCTCATGTTCAAAGTGAACACAGACTAC
AAGTCTAGTTTAAAGCATTTTCAGTTAGCCTTGATTGACTGTAATCCATGTACTTTGTCCAATGCTGAAATTCAATTTCATATTGCCCAT
TTGTATGAAACCCAGAGGAAGTATCATTCTGCAAAGGAGGCATATGAACAACTTTTGCAGACAGAAAACCTTCCTGCACAAGTAAAAGCA
ACTGTATTGCAACAGTTAGGTTGGATGCATCATAATATGGATCTAGTAGGAGACAAAGCCACAAAGGAAAGCTATGCTATTCAGTATCTC
CAAAAGTCTTTGGAGGCAGATCCTAATTCTGGCCAATCGTGGTATTTTCTTGGAAGTGTGTTGTATCAGCAGCAAAATCAGCCTATGGAT
GCTTTACAGGCATATATTTGTGCTGTACAATTGGACCATGGGCATGCCGCAGCCTGGATGGACCTAGGTACTCTCTATGAATCCTGCAAT
CAACCTCAAGATGCCATTAAATGCTACCTAAATGCAGCTAGAAGCAAACGTTGTAGTAATACCTCTACGCTTGCTGCAAGAATTAAATTT
CTACAGCAATCCTTGTCACTACACATGATTACTTCTAGCCAAGTAGAAGGCCTGTCCAGTCCTGCCAAGAAGAAAAGAACATCTAGTCCA
ACAAAGAATACTTCTGACAATTGGAGTGGTGGACATGCTGTGTCACATCCTCCAGTACAGCAACAAGCTCATTCATGGTGTTTGACACCA
CAGAAATTACAGCATTTGGAACAGCTCCGCGCAAATAGAAATAATTTAAATCCAGCACAGAAACTGATGCTGGAACAGCTGGAAAGTCAG
TTTGTCTTAATGCAACAACACCAAATGAGACCAACAGGAGTTGCACAGGTACGATCTACTGGAATTCCTAATGGGCCAACAGCTGACTCA
TCACTGCCTACAAACTCAGTCTCTGGCCAGCAGCCACAGCTTGCTCTGACCAGAGTGCCTAGCGTCTCTCAGCCTGGAGTCCGTCCTGCC
TGCCCTGGGCAGCCTTTGGCCAATGGACCCTTTTCTGCAGGCCATGTTCCCTGTAGCACATCAAGAACGCTGGGAAGTACAGACACTATT
TTGATAGGCAATAATCATATAACAGGAAGTGGAAGTAATGGAAACGTGCCTTACCTGCAGCGAAACGCACTCACTCTACCTCATAACCGC
ACAAACCTGACCAGCAGCGCAGAGGAGCCGTGGAAAAACCAACTATCTAACTCCACTCAGGGGCTTCACAAAGGTCAGAGTTCACATTCG
GCAGGTCCTAATGGTGAACGACCTCTCTCTTCCACTGGGCCTTCCCAGCATCTCCAGGCAGCTGGCTCTGGTATTCAGAATCAGAACGGA
CATCCCACCCTGCCTAGCAATTCAGTAACACAGGGGGCTGCTCTCAATCACCTCTCCTCTCACACTGCTACCTCAGGTGGACAACAAGGC
ATTACCTTAACCAAAGAGAGCAAGCCTTCAGGAAACATATTGACGGTGCCTGAAACAAGCAGGCACACTGGAGAGACACCTAACAGCACT
GCCAGTGTCGAGGGACTTCCTAATCATGTCCATCAGATGACGGCAGATGCTGTTTGCAGTCCTAGCCATGGAGATTCTAAGTCACCAGGT
TTACTAAGTTCAGACAATCCTCAGCTCTCTGCCTTGTTGATGGGAAAAGCCAATAACAATGTGGGTACTGGAACCTGTGACAAAGTCAAT
AACATCCACCCAGCTGTTCATACAAAGACTGATAACTCTGTTGCCTCTTCACCATCTTCAGCCATTTCAACAGCAACACCTTCTCCAAAA
TCCACTGAGCAGACAACCACAAACAGTGTTACCAGCCTTAACAGCCCTCACAGTGGGCTACACACAATTAATGGAGAAGGGATGGAAGAA
TCTCAGAGCCCCATGAAAACAGATCTGCTTCTGGTTAACCACAAACCTAGTCCACAGATCATACCATCAATGTCTGTGTCCATATACCCC
AGCTCAGCAGAAGTTCTGAAGGCATGCAGGAATCTAGGTAAAAATGGCTTATCTAACAGTAGCATTTTGTTGGATAAATGTCCACCTCCA
AGACCACCATCTTCACCATACCCTCCCTTGCCAAAGGACAAGTTGAATCCACCTACACCTAGTATTTACTTGGAAAATAAACGTGATGCT
TTCTTTCCTCCATTACATCAATTTTGTACAAATCCGAACAACCCTGTTACAGTAATACGTGGCCTTGCTGGAGCTCTTAAGTTAGACCTG
GGACTTTTCTCTACTAAAACTTTGGTGGAAGCTAACAATGAACATATGGTAGAAGTGAGGACACAGTTGTTGCAGCCAGCAGATGAAAAC
TGGGATCCCACTGGAACAAAGAAAATCTGGCATTGTGAAAGTAATAGATCTCATACTACAATTGCTAAATATGCACAGTACCAGGCCTCC
TCATTCCAGGAATCATTGAGAGAAGAAAATGAAAAAAGAAGTCATCATAAAGACCACTCAGATAGTGAATCTACATCGTCAGATAATTCT
GGGAGGAGGAGGAAAGGACCCTTTAAAACCATAAAGTTTGGGACCAATATTGACCTATCTGATGACAAAAAGTGGAAGTTGCAGCTACAT
GAGCTGACTAAACTTCCTGCTTTTGTGCGTGTCGTATCAGCAGGAAATCTTCTAAGCCATGTTGGTCATACCATATTGGGCATGAACACA
GTTCAACTATACATGAAAGTTCCAGGGAGCAGAACACCAGGTCATCAGGAAAATAACAACTTCTGTTCAGTTAACATAAATATTGGCCCA
GGTGACTGTGAATGGTTTGTTGTTCCTGAAGGTTACTGGGGTGTTCTGAATGACTTCTGTGAAAAAAATAATTTGAATTTCCTAATGGGT
TCTTGGTGGCCCAATCTTGAAGATCTTTATGAAGCAAATGTTCCAGTGTATAGGTTTATTCAGCGACCTGGAGATTTGGTCTGGATAAAT
GCAGGCACTGTTCATTGGGTTCAGGCTATTGGCTGGTGCAACAACATTGCTTGGAATGTTGGTCCACTTACAGCCTGCCAGTATAAATTG
GCAGTGGAACGGTACGAATGGAACAAATTGCAAAGTGTGAAGTCAATAGTACCCATGGTTCATCTTTCCTGGAATATGGCACGAAATATC
AAGGTCTCAGATCCAAAGCTTTTTGAAATGATTAAGTATTGTCTTCTAAGAACTCTGAAGCAATGTCAGACATTGAGGGAAGCTCTCATT
GCTGCAGGAAAAGAGATTATATGGCATGGGCGGACAAAAGAAGAACCAGCTCATTACTGTAGCATTTGTGAAGTGGAGGTTTTTGATCTG
CTTTTTGTCACTAATGAGAGTAATTCACGAAAGACCTACATAGTACATTGCCAAGATTGTGCACGAAAAACAAGCGGAAACTTGGAAAAC
TTTGTGGTGCTAGAACAGTACAAAATGGAGGACCTGATGCAAGTCTATGACCAATTTACATTAGCTCCTCCATTACCATCCGCCTCATCT
TGATATTGTTCCATGGACATTAAATGAGACCTTTTCTGCTATTCAGGAAATAACCCAGTTCTGCACCACTGGTTTTTGTAGCTATCTCGT

>97776_97776_2_UTY-KDM6A_UTY_chrY_15470343_ENST00000540140_KDM6A_chrX_44920568_ENST00000382899_length(amino acids)=1350AA_BP=10
MKSCAVSLTTAAVAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFVRLHEDGARTKTLLGKAVRCYESLILKAEGKVES
DFFCQLGHFNLLLEDYSKALSAYQRYYSLQADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDY
KSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKATVLQQLGWMHHNMDLVGDKATKESYAIQYL
QKSLEADPNSGQSWYFLGSVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNAARSKRCSNTSTLAARIKF
LQQSLSLHMITSSQVEGLSSPAKKKRTSSPTKNTSDNWSGGHAVSHPPVQQQAHSWCLTPQKLQHLEQLRANRNNLNPAQKLMLEQLESQ
FVLMQQHQMRPTGVAQVRSTGIPNGPTADSSLPTNSVSGQQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTLGSTDTI
LIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQSSHSAGPNGERPLSSTGPSQHLQAAGSGIQNQNG
HPTLPSNSVTQGAALNHLSSHTATSGGQQGITLTKESKPSGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSPG
LLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPKSTEQTTTNSVTSLNSPHSGLHTINGEGMEE
SQSPMKTDLLLVNHKPSPQIIPSMSVSIYPSSAEVLKACRNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTPSIYLENKRDA
FFPPLHQFCTNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKIWHCESNRSHTTIAKYAQYQAS
SFQESLREENEKRSHHKDHSDSESTSSDNSGRRRKGPFKTIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHTILGMNT
VQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFCEKNNLNFLMGSWWPNLEDLYEANVPVYRFIQRPGDLVWIN
AGTVHWVQAIGWCNNIAWNVGPLTACQYKLAVERYEWNKLQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIKYCLLRTLKQCQTLREALI
AAGKEIIWHGRTKEEPAHYCSICEVEVFDLLFVTNESNSRKTYIVHCQDCARKTSGNLENFVVLEQYKMEDLMQVYDQFTLAPPLPSASS

--------------------------------------------------------------
>97776_97776_3_UTY-KDM6A_UTY_chrY_15470343_ENST00000540140_KDM6A_chrX_44920568_ENST00000536777_length(transcript)=4150nt_BP=1176nt
ATGAAATCCTGCGCAGTGTCGCTCACTACCGCCGCTGTTGCCTTCGGTGATGAGGCAAAGAAAATGGCGGAAGGAAAAGCGAGCCGCGAG
AGTGAAGAGGAGTCTGTTAGCCTGACAGTCGAGGAAAGGGAGGCGCTTGGTGGCATGGACAGCCGTCTCTTCGGGTTCGTGAGGCTTCAT
GAAGATGGCGCCAGAACGAAGACCCTACTAGGCAAGGCTGTTCGCTGCTACGAATCTTTAATCTTAAAAGCTGAAGGAAAAGTGGAGTCT
GACTTCTTTTGCCAATTAGGTCACTTCAACCTCTTGTTGGAAGATTATTCAAAAGCATTATCTGCATATCAGAGATATTACAGTTTACAG
GCTGACTACTGGAAGAATGCTGCGTTTTTATATGGCCTTGGTTTGGTCTACTTCTACTACAATGCATTTCATTGGGCAATTAAAGCATTT
CAAGATGTCCTTTATGTTGACCCCAGCTTTTGTCGAGCCAAGGAAATTCATTTACGACTTGGGCTCATGTTCAAAGTGAACACAGACTAC
AAGTCTAGTTTAAAGCATTTTCAGTTAGCCTTGATTGACTGTAATCCATGTACTTTGTCCAATGCTGAAATTCAATTTCATATTGCCCAT
TTGTATGAAACCCAGAGGAAGTATCATTCTGCAAAGGAGGCATATGAACAACTTTTGCAGACAGAAAACCTTCCTGCACAAGTAAAAGCA
ACTGTATTGCAACAGTTAGGTTGGATGCATCATAATATGGATCTAGTAGGAGACAAAGCCACAAAGGAAAGCTATGCTATTCAGTATCTC
CAAAAGTCTTTGGAGGCAGATCCTAATTCTGGCCAATCGTGGTATTTTCTTGGAAGTGTGTTGTATCAGCAGCAAAATCAGCCTATGGAT
GCTTTACAGGCATATATTTGTGCTGTACAATTGGACCATGGGCATGCCGCAGCCTGGATGGACCTAGGTACTCTCTATGAATCCTGCAAT
CAACCTCAAGATGCCATTAAATGCTACCTAAATGCAGCTAGAAGCAAACGTTGTAGTAATACCTCTACGCTTGCTGCAAGAATTAAATTT
CTACAGCAATCCTTGTCACTACACATGATTACTTCTAGCCAAGTAGAAGGCCTGTCCAGTCCTGCCAAGAAGAAAAGAACATCTAGTCCA
ACAAAGAATACTTCTGACAATTGGAGTGGTGGACATGCTGTGTCACATCCTCCAGTACAGCAACAAGCTCATTCATGGTGTTTGACACCA
CAGAAATTACAGCATTTGGAACAGCTCCGCGCAAATAGAAATAATTTAAATCCAGCACAGAAACTGATGCTGGAACAGCTGGAAAGTCAG
TTTGTCTTAATGCAACAACACCAAATGAGACCAACAGGAGTTGCACAGGTACGATCTACTGGAATTCCTAATGGGCCAACAGCTGACTCA
TCACTGCCTACAAACTCAGTCTCTGGCCAGCAGCCACAGCTTGCTCTGACCAGAGTGCCTAGCGTCTCTCAGCCTGGAGTCCGTCCTGCC
TGCCCTGGGCAGCCTTTGGCCAATGGACCCTTTTCTGCAGGCCATGTTCCCTGTAGCACATCAAGAACGCTGGGAAGTACAGACACTATT
TTGATAGGCAATAATCATATAACAGGAAGTGGAAGTAATGGAAACGTGCCTTACCTGCAGCGAAACGCACTCACTCTACCTCATAACCGC
ACAAACCTGACCAGCAGCGCAGAGGAGCCGTGGAAAAACCAACTATCTAACTCCACTCAGGGGCTTCACAAAGGTCAGAGTTCACATTCG
GCAGGTCCTAATGGTGAACGACCTCTCTCTTCCACTGGGCCTTCCCAGCATCTCCAGGCAGCTGGCTCTGGTATTCAGAATCAGAACGGA
CATCCCACCCTGCCTAGCAATTCAGTAACACAGGGGGCTGCTCTCAATCACCTCTCCTCTCACACTGCTACCTCAGGTGGACAACAAGGC
ATTACCTTAACCAAAGAGAGCAAGCCTTCAGGAAACATATTGACGGTGCCTGAAACAAGCAGGCACACTGGAGAGACACCTAACAGCACT
GCCAGTGTCGAGGGACTTCCTAATCATGTCCATCAGATGACGGCAGATGCTGTTTGCAGTCCTAGCCATGGAGATTCTAAGTCACCAGGT
TTACTAAGTTCAGACAATCCTCAGCTCTCTGCCTTGTTGATGGGAAAAGCCAATAACAATGTGGGTACTGGAACCTGTGACAAAGTCAAT
AACATCCACCCAGCTGTTCATACAAAGACTGATAACTCTGTTGCCTCTTCACCATCTTCAGCCATTTCAACAGCAACACCTTCTCCAAAA
TCCACTGAGCAGACAACCACAAACAGTGTTACCAGCCTTAACAGCCCTCACAGTGGGCTACACACAATTAATGGAGAAGGGATGGAAGAA
TCTCAGAGCCCCATGAAAACAGATCTGCTTCTGGTTAACCACAAACCTAGTCCACAGATCATACCATCAATGTCTGTGTCCATATACCCC
AGCTCAGCAGAAGTTCTGAAGGCATGCAGGAATCTAGGTAAAAATGGCTTATCTAACAGTAGCATTTTGTTGGATAAATGTCCACCTCCA
AGACCACCATCTTCACCATACCCTCCCTTGCCAAAGGACAAGTTGAATCCACCTACACCTAGTATTTACTTGGAAAATAAACGTGATGCT
TTCTTTCCTCCATTACATCAATTTTGTACAAATCCGAACAACCCTGTTACAGTAATACGTGGCCTTGCTGGAGCTCTTAAGTTAGACCTG
GGACTTTTCTCTACTAAAACTTTGGTGGAAGCTAACAATGAACATATGGTAGAAGTGAGGACACAGTTGTTGCAGCCAGCAGATGAAAAC
TGGGATCCCACTGGAACAAAGAAAATCTGGCATTGTGAAAGTAATAGATCTCATACTACAATTGCTAAATATGCACAGTACCAGGCCTCC
TCATTCCAGGAATCATTGAGAGAAGAAAATGAAAAAAGAAGTCATCATAAAGACCACTCAGATAGTGAATCTACATCGTCAGATAATTCT
GGGAGGAGGAGGAAAGGACCCTTTAAAACCATAAAGTTTGGGACCAATATTGACCTATCTGATGACAAAAAGTGGAAGTTGCAGCTACAT
GAGCTGACTAAACTTCCTGCTTTTGTGCGTGTCGTATCAGCAGGAAATCTTCTAAGCCATGTTGGTCATACCATATTGGGCATGAACACA
GTTCAACTATACATGAAAGTTCCAGGGAGCAGAACACCAGGTCATCAGGAAAATAACAACTTCTGTTCAGTTAACATAAATATTGGCCCA
GGTGACTGTGAATGGTTTGTTGTTCCTGAAGGTTACTGGGGTGTTCTGAATGACTTCTGTGAAAAAAATAATTTGAATTTCCTAATGGGT
TCTTGGTGGCCCAATCTTGAAGATCTTTATGAAGCAAATGTTCCAGTGTATAGGTTTATTCAGCGACCTGGAGATTTGGTCTGGATAAAT
GCAGGCACTGTTCATTGGGTTCAGGCTATTGGCTGGTGCAACAACATTGCTTGGAATGTTGGTCCACTTACAGCCTGCCAGTATAAATTG
GCAGTGGAACGGTACGAATGGAACAAATTGCAAAGTGTGAAGTCAATAGTACCCATGGTTCATCTTTCCTGGAATATGGCACGAAATATC
AAGGTCTCAGATCCAAAGCTTTTTGAAATGATTAAGTATTGTCTTCTAAGAACTCTGAAGCAATGTCAGACATTGAGGGAAGCTCTCATT
GCTGCAGGAAAAGAGATTATATGGCATGGGCGGACAAAAGAAGAACCAGCTCATTACTGTAGCATTTGTGAAGTGGAGGTTTTTGATCTG
CTTTTTGTCACTAATGAGAGTAATTCACGAAAGACCTACATAGTACATTGCCAAGATTGTGCACGAAAAACAAGCGGAAACTTGGAAAAC
TTTGTGGTGCTAGAACAGTACAAAATGGAGGACCTGATGCAAGTCTATGACCAATTTACATTAGCTCCTCCATTACCATCCGCCTCATCT
TGATATTGTTCCATGGACATTAAATGAGACCTTTTCTGCTATTCAGGAAATAACCCAGTTCTGCACCACTGGTTTTTGTAGCTATCTCGT

>97776_97776_3_UTY-KDM6A_UTY_chrY_15470343_ENST00000540140_KDM6A_chrX_44920568_ENST00000536777_length(amino acids)=1350AA_BP=10
MKSCAVSLTTAAVAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFVRLHEDGARTKTLLGKAVRCYESLILKAEGKVES
DFFCQLGHFNLLLEDYSKALSAYQRYYSLQADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDY
KSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKATVLQQLGWMHHNMDLVGDKATKESYAIQYL
QKSLEADPNSGQSWYFLGSVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNAARSKRCSNTSTLAARIKF
LQQSLSLHMITSSQVEGLSSPAKKKRTSSPTKNTSDNWSGGHAVSHPPVQQQAHSWCLTPQKLQHLEQLRANRNNLNPAQKLMLEQLESQ
FVLMQQHQMRPTGVAQVRSTGIPNGPTADSSLPTNSVSGQQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTLGSTDTI
LIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQSSHSAGPNGERPLSSTGPSQHLQAAGSGIQNQNG
HPTLPSNSVTQGAALNHLSSHTATSGGQQGITLTKESKPSGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSPG
LLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPKSTEQTTTNSVTSLNSPHSGLHTINGEGMEE
SQSPMKTDLLLVNHKPSPQIIPSMSVSIYPSSAEVLKACRNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTPSIYLENKRDA
FFPPLHQFCTNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKIWHCESNRSHTTIAKYAQYQAS
SFQESLREENEKRSHHKDHSDSESTSSDNSGRRRKGPFKTIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHTILGMNT
VQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFCEKNNLNFLMGSWWPNLEDLYEANVPVYRFIQRPGDLVWIN
AGTVHWVQAIGWCNNIAWNVGPLTACQYKLAVERYEWNKLQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIKYCLLRTLKQCQTLREALI
AAGKEIIWHGRTKEEPAHYCSICEVEVFDLLFVTNESNSRKTYIVHCQDCARKTSGNLENFVVLEQYKMEDLMQVYDQFTLAPPLPSASS

--------------------------------------------------------------
>97776_97776_4_UTY-KDM6A_UTY_chrY_15470343_ENST00000540140_KDM6A_chrX_44920568_ENST00000543216_length(transcript)=3951nt_BP=1176nt
ATGAAATCCTGCGCAGTGTCGCTCACTACCGCCGCTGTTGCCTTCGGTGATGAGGCAAAGAAAATGGCGGAAGGAAAAGCGAGCCGCGAG
AGTGAAGAGGAGTCTGTTAGCCTGACAGTCGAGGAAAGGGAGGCGCTTGGTGGCATGGACAGCCGTCTCTTCGGGTTCGTGAGGCTTCAT
GAAGATGGCGCCAGAACGAAGACCCTACTAGGCAAGGCTGTTCGCTGCTACGAATCTTTAATCTTAAAAGCTGAAGGAAAAGTGGAGTCT
GACTTCTTTTGCCAATTAGGTCACTTCAACCTCTTGTTGGAAGATTATTCAAAAGCATTATCTGCATATCAGAGATATTACAGTTTACAG
GCTGACTACTGGAAGAATGCTGCGTTTTTATATGGCCTTGGTTTGGTCTACTTCTACTACAATGCATTTCATTGGGCAATTAAAGCATTT
CAAGATGTCCTTTATGTTGACCCCAGCTTTTGTCGAGCCAAGGAAATTCATTTACGACTTGGGCTCATGTTCAAAGTGAACACAGACTAC
AAGTCTAGTTTAAAGCATTTTCAGTTAGCCTTGATTGACTGTAATCCATGTACTTTGTCCAATGCTGAAATTCAATTTCATATTGCCCAT
TTGTATGAAACCCAGAGGAAGTATCATTCTGCAAAGGAGGCATATGAACAACTTTTGCAGACAGAAAACCTTCCTGCACAAGTAAAAGCA
ACTGTATTGCAACAGTTAGGTTGGATGCATCATAATATGGATCTAGTAGGAGACAAAGCCACAAAGGAAAGCTATGCTATTCAGTATCTC
CAAAAGTCTTTGGAGGCAGATCCTAATTCTGGCCAATCGTGGTATTTTCTTGGAAGTGTGTTGTATCAGCAGCAAAATCAGCCTATGGAT
GCTTTACAGGCATATATTTGTGCTGTACAATTGGACCATGGGCATGCCGCAGCCTGGATGGACCTAGGTACTCTCTATGAATCCTGCAAT
CAACCTCAAGATGCCATTAAATGCTACCTAAATGCAGCTAGAAGCAAACGTTGTAGTAATACCTCTACGCTTGCTGCAAGAATTAAATTT
CTACAGCAATCCTTGTCACTACACATGATTACTTCTAGCCAAGTAGAAGGCCTGTCCAGTCCTGCCAAGAAGAAAAGAACATCTAGTCCA
ACAAAGAATACTTCTGACAATTGGAGTGGTGGACATGCTGTGTCACATCCTCCAGTACAGCAACAAGCTCATTCATGGTGTTTGACACCA
CAGAAATTACAGATGAGACCAACAGGAGTTGCACAGGTACGATCTACTGGAATTCCTAATGGGCCAACAGCTGACTCATCACTGCCTACA
AACTCAGTCTCTGGCCAGCAGCCACAGCTTGCTCTGACCAGAGTGCCTAGCGTCTCTCAGCCTGGAGTCCGTCCTGCCTGCCCTGGGCAG
CCTTTGGCCAATGGACCCTTTTCTGCAGGCCATGTTCCCTGTAGCACATCAAGAACGCTGGGAAGTACAGACACTATTTTGATAGGCAAT
AATCATATAACAGGAAGTGGAAGTAATGGAAACGTGCCTTACCTGCAGCGAAACGCACTCACTCTACCTCATAACCGCACAAACCTGACC
AGCAGCGCAGAGGAGCCGTGGAAAAACCAACTATCTAACTCCACTCAGGGGCTTCACAAAGGTCAGAGTTCACATTCGGCAGGTCCTAAT
GGTGAACGACCTCTCTCTTCCACTGGGCCTTCCCAGCATCTCCAGGCAGCTGGCTCTGGTATTCAGAATCAGAACGGACATCCCACCCTG
CCTAGCAATTCAGTAACACAGGGGGCTGCTCTCAATCACCTCTCCTCTCACACTGCTACCTCAGGTGGACAACAAGGCATTACCTTAACC
AAAGAGAGCAAGCCTTCAGGAAACATATTGACGGTGCCTGAAACAAGCAGGCACACTGGAGAGACACCTAACAGCACTGCCAGTGTCGAG
GGACTTCCTAATCATGTCCATCAGATGACGGCAGATGCTGTTTGCAGTCCTAGCCATGGAGATTCTAAGTCACCAGGTTTACTAAGTTCA
GACAATCCTCAGCTCTCTGCCTTGTTGATGGGAAAAGCCAATAACAATGTGGGTACTGGAACCTGTGACAAAGTCAATAACATCCACCCA
GCTGTTCATACAAAGACTGATAACTCTGTTGCCTCTTCACCATCTTCAGCCATTTCAACAGCAACACCTTCTCCAAAATCCACTGAGCAG
ACAACCACAAACAGTGTTACCAGCCTTAACAGCCCTCACAGTGGGCTACACACAATTAATGGAGAAGGGATGGAAGAATCTCAGAGCCCC
ATGAAAACAGATCTGCTTCTGGTTAACCACAAACCTAGTCCACAGATCATACCATCAATGTCTGTGTCCATATACCCCAGCTCAGCAGAA
GTTCTGAAGGCATGCAGGAATCTAGGTAAAAATGGCTTATCTAACAGTAGCATTTTGTTGGATAAATGTCCACCTCCAAGACCACCATCT
TCACCATACCCTCCCTTGCCAAAGGACAAGTTGAATCCACCTACACCTAGTATTTACTTGGAAAATAAACGTGATGCTTTCTTTCCTCCA
TTACATCAATTTTGTACAAATCCGAACAACCCTGTTACAGTAATACGTGGCCTTGCTGGAGCTCTTAAGTTAGACCTGGGACTTTTCTCT
ACTAAAACTTTGGTGGAAGCTAACAATGAACATATGGTAGAAGTGAGGACACAGTTGTTGCAGCCAGCAGATGAAAACTGGGATCCCACT
GGAACAAAGAAAATCTGGCATTGTGAAAGTAATAGATCTCATACTACAATTGCTAAATATGCACAGTACCAGGCCTCCTCATTCCAGGAA
TCATTGAGAGAAGAAAATGAAAAAAGAAGTCATCATAAAGACCACTCAGATAGTGAATCTACATCGTCAGATAATTCTGGGAGGAGGAGG
AAAGGACCCTTTAAAACCATAAAGTTTGGGACCAATATTGACCTATCTGATGACAAAAAGTGGAAGTTGCAGCTACATGAGCTGACTAAA
CTTCCTGCTTTTGTGCGTGTCGTATCAGCAGGAAATCTTCTAAGCCATGTTGGTCATACCATATTGGGCATGAACACAGTTCAACTATAC
ATGAAAGTTCCAGGGAGCAGAACACCAGGTCATCAGGAAAATAACAACTTCTGTTCAGTTAACATAAATATTGGCCCAGGTGACTGTGAA
TGGTTTGTTGTTCCTGAAGGTTACTGGGGTGTTCTGAATGACTTCTGTGAAAAAAATAATTTGAATTTCCTAATGGGTTCTTGGTGGCCC
AATCTTGAAGATCTTTATGAAGCAAATGTTCCAGTGTATAGGTTTATTCAGCGACCTGGAGATTTGGTCTGGATAAATGCAGGCACTGTT
CATTGGGTTCAGGCTATTGGCTGGTGCAACAACATTGCTTGGAATGTTGGTCCACTTACAGCCTGCCAGTATAAATTGGCAGTGGAACGG
TACGAATGGAACAAATTGCAAAGTGTGAAGTCAATAGTACCCATGGTTCATCTTTCCTGGAATATGGCACGAAATATCAAGGTCTCAGAT
CCAAAGCTTTTTGAAATGATTAAGTATTGTCTTCTAAGAACTCTGAAGCAATGTCAGACATTGAGGGAAGCTCTCATTGCTGCAGGAAAA
GAGATTATATGGCATGGGCGGACAAAAGAAGAACCAGCTCATTACTGTAGCATTTGTGAAGTGGAGGTTTTTGATCTGCTTTTTGTCACT
AATGAGAGTAATTCACGAAAGACCTACATAGTACATTGCCAAGATTGTGCACGAAAAACAAGCGGAAACTTGGAAAACTTTGTGGTGCTA

>97776_97776_4_UTY-KDM6A_UTY_chrY_15470343_ENST00000540140_KDM6A_chrX_44920568_ENST00000543216_length(amino acids)=1316AA_BP=10
MKSCAVSLTTAAVAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFVRLHEDGARTKTLLGKAVRCYESLILKAEGKVES
DFFCQLGHFNLLLEDYSKALSAYQRYYSLQADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDY
KSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKATVLQQLGWMHHNMDLVGDKATKESYAIQYL
QKSLEADPNSGQSWYFLGSVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNAARSKRCSNTSTLAARIKF
LQQSLSLHMITSSQVEGLSSPAKKKRTSSPTKNTSDNWSGGHAVSHPPVQQQAHSWCLTPQKLQMRPTGVAQVRSTGIPNGPTADSSLPT
NSVSGQQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTLGSTDTILIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLT
SSAEEPWKNQLSNSTQGLHKGQSSHSAGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHTATSGGQQGITLT
KESKPSGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHP
AVHTKTDNSVASSPSSAISTATPSPKSTEQTTTNSVTSLNSPHSGLHTINGEGMEESQSPMKTDLLLVNHKPSPQIIPSMSVSIYPSSAE
VLKACRNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFCTNPNNPVTVIRGLAGALKLDLGLFS
TKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKIWHCESNRSHTTIAKYAQYQASSFQESLREENEKRSHHKDHSDSESTSSDNSGRRR
KGPFKTIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHTILGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCE
WFVVPEGYWGVLNDFCEKNNLNFLMGSWWPNLEDLYEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNVGPLTACQYKLAVER
YEWNKLQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIKYCLLRTLKQCQTLREALIAAGKEIIWHGRTKEEPAHYCSICEVEVFDLLFVT

--------------------------------------------------------------
>97776_97776_5_UTY-KDM6A_UTY_chrY_15470343_ENST00000545955_KDM6A_chrX_44920568_ENST00000377967_length(transcript)=5478nt_BP=1410nt
ATGAAATCCTGCGCAGTGTCGCTCACTACCGCCGCTGTTGCCTTCGGTGATGAGGCAAAGAAAATGGCGGAAGGAAAAGCGAGCCGCGAG
AGTGAAGAGGAGTCTGTTAGCCTGACAGTCGAGGAAAGGGAGGCGCTTGGTGGCATGGACAGCCGTCTCTTCGGGTTCGTGAGGCTTCAT
GAAGATGGCGCCAGAACGAAGACCCTACTAGGCAAGGCTGTTCGCTGCTACGAATCTTTAATCTTAAAAGCTGAAGGAAAAGTGGAGTCT
GACTTCTTTTGCCAATTAGGTCACTTCAACCTCTTGTTGGAAGATTATTCAAAAGCATTATCTGCATATCAGAGATATTACAGTTTACAG
GCTGACTACTGGAAGAATGCTGCGTTTTTATATGGCCTTGGTTTGGTCTACTTCTACTACAATGCATTTCATTGGGCAATTAAAGCATTT
CAAGATGTCCTTTATGTTGACCCCAGCTTTTGTCGAGCCAAGGAAATTCATTTACGACTTGGGCTCATGTTCAAAGTGAACACAGACTAC
AAGTCTAGTTTAAAGCATTTTCAGTTAGCCTTGATTGACTGTAATCCATGTACTTTGTCCAATGCTGAAATTCAATTTCATATTGCCCAT
TTGTATGAAACCCAGAGGAAGTATCATTCTGCAAAGGAGGCATATGAACAACTTTTGCAGACAGAAAACCTTCCTGCACAAGTAAAAGCA
ACTGTATTGCAACAGTTAGGTTGGATGCATCATAATATGGATCTAGTAGGAGACAAAGCCACAAAGGAAAGCTATGCTATTCAGTATCTC
CAAAAGTCTTTGGAGGCAGATCCTAATTCTGGCCAATCGTGGTATTTTCTTGGAAGGTGTTATTCAAGTATTGGGAAAGTTCAGGATGCC
TTTATATCTTACAGGCAATCTATTGATAAATCAGAAGCAAGTGCAGATACATGGTGTTCAATAGGTGTGTTGTATCAGCAGCAAAATCAG
CCTATGGATGCTTTACAGGCATATATTTGTGCTGTACAATTGGACCATGGGCATGCCGCAGCCTGGATGGACCTAGGTACTCTCTATGAA
TCCTGCAATCAACCTCAAGATGCCATTAAATGCTACCTAAATGCAGCTAGAAGCAAACGTTGTAGTAATACCTCTACGCTTGCTGCAAGA
ATTAAATTTCTACAGGCTCAGTTGTGTAACCTTCCACAAAGTAGTCTACAGAATAAAACTAAATTACTTCCTAGTATTGAGGAGGCATGG
AGCCTACCAATCCCCGCAGAGCTTACCTCCAGGCAGGGTGCCATGAACACAGCACAGCAGCAATCCTTGTCACTACACATGATTACTTCT
AGCCAAGTAGAAGGCCTGTCCAGTCCTGCCAAGAAGAAAAGAACATCTAGTCCAACAAAGAATACTTCTGACAATTGGAGTGGTGGACAT
GCTGTGTCACATCCTCCAGTACAGCAACAAGCTCATTCATGGTGTTTGACACCACAGAAATTACAGCATTTGGAACAGCTCCGCGCAAAT
AGAAATAATTTAAATCCAGCACAGAAACTGATGCTGGAACAGCTGGAAAGTCAGTTTGTCTTAATGCAACAACACCAAATGAGACCAACA
GGAGTTGCACAGGTACGATCTACTGGAATTCCTAATGGGCCAACAGCTGACTCATCACTGCCTACAAACTCAGTCTCTGGCCAGCAGCCA
CAGCTTGCTCTGACCAGAGTGCCTAGCGTCTCTCAGCCTGGAGTCCGTCCTGCCTGCCCTGGGCAGCCTTTGGCCAATGGACCCTTTTCT
GCAGGCCATGTTCCCTGTAGCACATCAAGAACGCTGGGAAGTACAGACACTATTTTGATAGGCAATAATCATATAACAGGAAGTGGAAGT
AATGGAAACGTGCCTTACCTGCAGCGAAACGCACTCACTCTACCTCATAACCGCACAAACCTGACCAGCAGCGCAGAGGAGCCGTGGAAA
AACCAACTATCTAACTCCACTCAGGGGCTTCACAAAGGTCAGAGTTCACATTCGGCAGGTCCTAATGGTGAACGACCTCTCTCTTCCACT
GGGCCTTCCCAGCATCTCCAGGCAGCTGGCTCTGGTATTCAGAATCAGAACGGACATCCCACCCTGCCTAGCAATTCAGTAACACAGGGG
GCTGCTCTCAATCACCTCTCCTCTCACACTGCTACCTCAGGTGGACAACAAGGCATTACCTTAACCAAAGAGAGCAAGCCTTCAGGAAAC
ATATTGACGGTGCCTGAAACAAGCAGGCACACTGGAGAGACACCTAACAGCACTGCCAGTGTCGAGGGACTTCCTAATCATGTCCATCAG
ATGACGGCAGATGCTGTTTGCAGTCCTAGCCATGGAGATTCTAAGTCACCAGGTTTACTAAGTTCAGACAATCCTCAGCTCTCTGCCTTG
TTGATGGGAAAAGCCAATAACAATGTGGGTACTGGAACCTGTGACAAAGTCAATAACATCCACCCAGCTGTTCATACAAAGACTGATAAC
TCTGTTGCCTCTTCACCATCTTCAGCCATTTCAACAGCAACACCTTCTCCAAAATCCACTGAGCAGACAACCACAAACAGTGTTACCAGC
CTTAACAGCCCTCACAGTGGGCTACACACAATTAATGGAGAAGGGATGGAAGAATCTCAGAGCCCCATGAAAACAGATCTGCTTCTGGTT
AACCACAAACCTAGTCCACAGATCATACCATCAATGTCTGTGTCCATATACCCCAGCTCAGCAGAAGTTCTGAAGGCATGCAGGAATCTA
GGTAAAAATGGCTTATCTAACAGTAGCATTTTGTTGGATAAATGTCCACCTCCAAGACCACCATCTTCACCATACCCTCCCTTGCCAAAG
GACAAGTTGAATCCACCTACACCTAGTATTTACTTGGAAAATAAACGTGATGCTTTCTTTCCTCCATTACATCAATTTTGTACAAATCCG
AACAACCCTGTTACAGTAATACGTGGCCTTGCTGGAGCTCTTAAGTTAGACCTGGGACTTTTCTCTACTAAAACTTTGGTGGAAGCTAAC
AATGAACATATGGTAGAAGTGAGGACACAGTTGTTGCAGCCAGCAGATGAAAACTGGGATCCCACTGGAACAAAGAAAATCTGGCATTGT
GAAAGTAATAGATCTCATACTACAATTGCTAAATATGCACAGTACCAGGCCTCCTCATTCCAGGAATCATTGAGAGAAGAAAATGAAAAA
AGAAGTCATCATAAAGACCACTCAGATAGTGAATCTACATCGTCAGATAATTCTGGGAGGAGGAGGAAAGGACCCTTTAAAACCATAAAG
TTTGGGACCAATATTGACCTATCTGATGACAAAAAGTGGAAGTTGCAGCTACATGAGCTGACTAAACTTCCTGCTTTTGTGCGTGTCGTA
TCAGCAGGAAATCTTCTAAGCCATGTTGGTCATACCATATTGGGCATGAACACAGTTCAACTATACATGAAAGTTCCAGGGAGCAGAACA
CCAGGTCATCAGGAAAATAACAACTTCTGTTCAGTTAACATAAATATTGGCCCAGGTGACTGTGAATGGTTTGTTGTTCCTGAAGGTTAC
TGGGGTGTTCTGAATGACTTCTGTGAAAAAAATAATTTGAATTTCCTAATGGGTTCTTGGTGGCCCAATCTTGAAGATCTTTATGAAGCA
AATGTTCCAGTGTATAGGTTTATTCAGCGACCTGGAGATTTGGTCTGGATAAATGCAGGCACTGTTCATTGGGTTCAGGCTATTGGCTGG
TGCAACAACATTGCTTGGAATGTTGGTCCACTTACAGCCTGCCAGTATAAATTGGCAGTGGAACGGTACGAATGGAACAAATTGCAAAGT
GTGAAGTCAATAGTACCCATGGTTCATCTTTCCTGGAATATGGCACGAAATATCAAGGTCTCAGATCCAAAGCTTTTTGAAATGATTAAG
TATTGTCTTCTAAGAACTCTGAAGCAATGTCAGACATTGAGGGAAGCTCTCATTGCTGCAGGAAAAGAGATTATATGGCATGGGCGGACA
AAAGAAGAACCAGCTCATTACTGTAGCATTTGTGAAGTGGAGGTTTTTGATCTGCTTTTTGTCACTAATGAGAGTAATTCACGAAAGACC
TACATAGTACATTGCCAAGATTGTGCACGAAAAACAAGCGGAAACTTGGAAAACTTTGTGGTGCTAGAACAGTACAAAATGGAGGACCTG
ATGCAAGTCTATGACCAATTTACATTAGCTCCTCCATTACCATCCGCCTCATCTTGATATTGTTCCATGGACATTAAATGAGACCTTTTC
TGCTATTCAGGAAATAACCCAGTTCTGCACCACTGGTTTTTGTAGCTATCTCGTAAGGCTGCTGGCTGAAAACTGTGTCTATGCAACCTT
CCAAGTGCGGAGTGTCAACCAACTGGACGGGAGAGAGTACTGCTCCTACTCCAGGACTCTCACAAAGCTGATGAGCTGTACTTCAGAAAA
AAATAATAATTTCCATGTTTTGTATATATCTGACAAAACTGGCAACATCTTACAGACTACTGACTTGAAGACAACCTCTTTTATATTTCT
CTATTTCTGGGCTGATGAATTTGTTTTCATCTGTCTTTTCCCCCTTCAGAATTTTCCTTGGAAAAAAAATACTAGCCTAGCTGGTCATTT
CTTTGTAAGGTAGTTAGCAATTTTAAGTCTTTCTTTGGTCAACTTTTTTTTAATGTGAAAAGTTAGGTAAGACACTTTTTTACTGCTTTT
ATGTTTTTCTGTCTTGTTTTGAGACCATGATGGTTACACTTTTGGTTCCTAAATAAAATTTAAAAAATTAACAGCCAAGTCACAAAGGTA
ATGGATTGCACATAGACTAAGGAATAAACTTCAGATTTGTGATTTTTGTTTCTAATCTTGATGTAAATTTACACTATTTATAAATACATA
TTTATTGCTTGAAAATATTTGTGAATGGAATGCTGTTATTTTTTCCAGATTTACCTGCCATTGAAATTTTAAGGAGTTCTGTAATTTCAA
ACACTACTCCTATTACATTTTCTATGTGTAAATAAAACTGCTTAGCATTGTACAGAAACTTTTATTAAAATTGTTTAATGTTTAAAGAGT
TTTCTATTGTTTGAGTTTTAAAAAAGACTTTATGTACAGTGCCCAGTTTTTGTTCATTTTTGAAATCTGATTATATATATTTTATATATA
CTTATGTATGTATATATAATATATATAGAAATCTGGATATATATGTATAAATCTTTAGAACTTAAATTTTTCTCGTTTTAAGTTTCACAT
CTATGGTAGATTTTTGAGGTGTCTACTGTAAAGTATTGCTTACAAAAAGTATGATTATTTTTAAAGAAATATATATGGTATGTATCCTCA

>97776_97776_5_UTY-KDM6A_UTY_chrY_15470343_ENST00000545955_KDM6A_chrX_44920568_ENST00000377967_length(amino acids)=1428AA_BP=10
MKSCAVSLTTAAVAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFVRLHEDGARTKTLLGKAVRCYESLILKAEGKVES
DFFCQLGHFNLLLEDYSKALSAYQRYYSLQADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDY
KSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKATVLQQLGWMHHNMDLVGDKATKESYAIQYL
QKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYE
SCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQAQLCNLPQSSLQNKTKLLPSIEEAWSLPIPAELTSRQGAMNTAQQQSLSLHMITS
SQVEGLSSPAKKKRTSSPTKNTSDNWSGGHAVSHPPVQQQAHSWCLTPQKLQHLEQLRANRNNLNPAQKLMLEQLESQFVLMQQHQMRPT
GVAQVRSTGIPNGPTADSSLPTNSVSGQQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTLGSTDTILIGNNHITGSGS
NGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQSSHSAGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQG
AALNHLSSHTATSGGQQGITLTKESKPSGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSPGLLSSDNPQLSAL
LMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPKSTEQTTTNSVTSLNSPHSGLHTINGEGMEESQSPMKTDLLLV
NHKPSPQIIPSMSVSIYPSSAEVLKACRNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFCTNP
NNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKIWHCESNRSHTTIAKYAQYQASSFQESLREENEK
RSHHKDHSDSESTSSDNSGRRRKGPFKTIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHTILGMNTVQLYMKVPGSRT
PGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFCEKNNLNFLMGSWWPNLEDLYEANVPVYRFIQRPGDLVWINAGTVHWVQAIGW
CNNIAWNVGPLTACQYKLAVERYEWNKLQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIKYCLLRTLKQCQTLREALIAAGKEIIWHGRT

--------------------------------------------------------------
>97776_97776_6_UTY-KDM6A_UTY_chrY_15470343_ENST00000545955_KDM6A_chrX_44920568_ENST00000382899_length(transcript)=4380nt_BP=1410nt
ATGAAATCCTGCGCAGTGTCGCTCACTACCGCCGCTGTTGCCTTCGGTGATGAGGCAAAGAAAATGGCGGAAGGAAAAGCGAGCCGCGAG
AGTGAAGAGGAGTCTGTTAGCCTGACAGTCGAGGAAAGGGAGGCGCTTGGTGGCATGGACAGCCGTCTCTTCGGGTTCGTGAGGCTTCAT
GAAGATGGCGCCAGAACGAAGACCCTACTAGGCAAGGCTGTTCGCTGCTACGAATCTTTAATCTTAAAAGCTGAAGGAAAAGTGGAGTCT
GACTTCTTTTGCCAATTAGGTCACTTCAACCTCTTGTTGGAAGATTATTCAAAAGCATTATCTGCATATCAGAGATATTACAGTTTACAG
GCTGACTACTGGAAGAATGCTGCGTTTTTATATGGCCTTGGTTTGGTCTACTTCTACTACAATGCATTTCATTGGGCAATTAAAGCATTT
CAAGATGTCCTTTATGTTGACCCCAGCTTTTGTCGAGCCAAGGAAATTCATTTACGACTTGGGCTCATGTTCAAAGTGAACACAGACTAC
AAGTCTAGTTTAAAGCATTTTCAGTTAGCCTTGATTGACTGTAATCCATGTACTTTGTCCAATGCTGAAATTCAATTTCATATTGCCCAT
TTGTATGAAACCCAGAGGAAGTATCATTCTGCAAAGGAGGCATATGAACAACTTTTGCAGACAGAAAACCTTCCTGCACAAGTAAAAGCA
ACTGTATTGCAACAGTTAGGTTGGATGCATCATAATATGGATCTAGTAGGAGACAAAGCCACAAAGGAAAGCTATGCTATTCAGTATCTC
CAAAAGTCTTTGGAGGCAGATCCTAATTCTGGCCAATCGTGGTATTTTCTTGGAAGGTGTTATTCAAGTATTGGGAAAGTTCAGGATGCC
TTTATATCTTACAGGCAATCTATTGATAAATCAGAAGCAAGTGCAGATACATGGTGTTCAATAGGTGTGTTGTATCAGCAGCAAAATCAG
CCTATGGATGCTTTACAGGCATATATTTGTGCTGTACAATTGGACCATGGGCATGCCGCAGCCTGGATGGACCTAGGTACTCTCTATGAA
TCCTGCAATCAACCTCAAGATGCCATTAAATGCTACCTAAATGCAGCTAGAAGCAAACGTTGTAGTAATACCTCTACGCTTGCTGCAAGA
ATTAAATTTCTACAGGCTCAGTTGTGTAACCTTCCACAAAGTAGTCTACAGAATAAAACTAAATTACTTCCTAGTATTGAGGAGGCATGG
AGCCTACCAATCCCCGCAGAGCTTACCTCCAGGCAGGGTGCCATGAACACAGCACAGCAGCAATCCTTGTCACTACACATGATTACTTCT
AGCCAAGTAGAAGGCCTGTCCAGTCCTGCCAAGAAGAAAAGAACATCTAGTCCAACAAAGAATACTTCTGACAATTGGAGTGGTGGACAT
GCTGTGTCACATCCTCCAGTACAGCAACAAGCTCATTCATGGTGTTTGACACCACAGAAATTACAGCATTTGGAACAGCTCCGCGCAAAT
AGAAATAATTTAAATCCAGCACAGAAACTGATGCTGGAACAGCTGGAAAGTCAGTTTGTCTTAATGCAACAACACCAAATGAGACCAACA
GGAGTTGCACAGGTACGATCTACTGGAATTCCTAATGGGCCAACAGCTGACTCATCACTGCCTACAAACTCAGTCTCTGGCCAGCAGCCA
CAGCTTGCTCTGACCAGAGTGCCTAGCGTCTCTCAGCCTGGAGTCCGTCCTGCCTGCCCTGGGCAGCCTTTGGCCAATGGACCCTTTTCT
GCAGGCCATGTTCCCTGTAGCACATCAAGAACGCTGGGAAGTACAGACACTATTTTGATAGGCAATAATCATATAACAGGAAGTGGAAGT
AATGGAAACGTGCCTTACCTGCAGCGAAACGCACTCACTCTACCTCATAACCGCACAAACCTGACCAGCAGCGCAGAGGAGCCGTGGAAA
AACCAACTATCTAACTCCACTCAGGGGCTTCACAAAGGTCAGAGTTCACATTCGGCAGGTCCTAATGGTGAACGACCTCTCTCTTCCACT
GGGCCTTCCCAGCATCTCCAGGCAGCTGGCTCTGGTATTCAGAATCAGAACGGACATCCCACCCTGCCTAGCAATTCAGTAACACAGGGG
GCTGCTCTCAATCACCTCTCCTCTCACACTGCTACCTCAGGTGGACAACAAGGCATTACCTTAACCAAAGAGAGCAAGCCTTCAGGAAAC
ATATTGACGGTGCCTGAAACAAGCAGGCACACTGGAGAGACACCTAACAGCACTGCCAGTGTCGAGGGACTTCCTAATCATGTCCATCAG
ATGACGGCAGATGCTGTTTGCAGTCCTAGCCATGGAGATTCTAAGTCACCAGGTTTACTAAGTTCAGACAATCCTCAGCTCTCTGCCTTG
TTGATGGGAAAAGCCAATAACAATGTGGGTACTGGAACCTGTGACAAAGTCAATAACATCCACCCAGCTGTTCATACAAAGACTGATAAC
TCTGTTGCCTCTTCACCATCTTCAGCCATTTCAACAGCAACACCTTCTCCAAAATCCACTGAGCAGACAACCACAAACAGTGTTACCAGC
CTTAACAGCCCTCACAGTGGGCTACACACAATTAATGGAGAAGGGATGGAAGAATCTCAGAGCCCCATGAAAACAGATCTGCTTCTGGTT
AACCACAAACCTAGTCCACAGATCATACCATCAATGTCTGTGTCCATATACCCCAGCTCAGCAGAAGTTCTGAAGGCATGCAGGAATCTA
GGTAAAAATGGCTTATCTAACAGTAGCATTTTGTTGGATAAATGTCCACCTCCAAGACCACCATCTTCACCATACCCTCCCTTGCCAAAG
GACAAGTTGAATCCACCTACACCTAGTATTTACTTGGAAAATAAACGTGATGCTTTCTTTCCTCCATTACATCAATTTTGTACAAATCCG
AACAACCCTGTTACAGTAATACGTGGCCTTGCTGGAGCTCTTAAGTTAGACCTGGGACTTTTCTCTACTAAAACTTTGGTGGAAGCTAAC
AATGAACATATGGTAGAAGTGAGGACACAGTTGTTGCAGCCAGCAGATGAAAACTGGGATCCCACTGGAACAAAGAAAATCTGGCATTGT
GAAAGTAATAGATCTCATACTACAATTGCTAAATATGCACAGTACCAGGCCTCCTCATTCCAGGAATCATTGAGAGAAGAAAATGAAAAA
AGAAGTCATCATAAAGACCACTCAGATAGTGAATCTACATCGTCAGATAATTCTGGGAGGAGGAGGAAAGGACCCTTTAAAACCATAAAG
TTTGGGACCAATATTGACCTATCTGATGACAAAAAGTGGAAGTTGCAGCTACATGAGCTGACTAAACTTCCTGCTTTTGTGCGTGTCGTA
TCAGCAGGAAATCTTCTAAGCCATGTTGGTCATACCATATTGGGCATGAACACAGTTCAACTATACATGAAAGTTCCAGGGAGCAGAACA
CCAGGTCATCAGGAAAATAACAACTTCTGTTCAGTTAACATAAATATTGGCCCAGGTGACTGTGAATGGTTTGTTGTTCCTGAAGGTTAC
TGGGGTGTTCTGAATGACTTCTGTGAAAAAAATAATTTGAATTTCCTAATGGGTTCTTGGTGGCCCAATCTTGAAGATCTTTATGAAGCA
AATGTTCCAGTGTATAGGTTTATTCAGCGACCTGGAGATTTGGTCTGGATAAATGCAGGCACTGTTCATTGGGTTCAGGCTATTGGCTGG
TGCAACAACATTGCTTGGAATGTTGGTCCACTTACAGCCTGCCAGTATAAATTGGCAGTGGAACGGTACGAATGGAACAAATTGCAAAGT
GTGAAGTCAATAGTACCCATGGTTCATCTTTCCTGGAATATGGCACGAAATATCAAGGTCTCAGATCCAAAGCTTTTTGAAATGATTAAG
TATTGTCTTCTAAGAACTCTGAAGCAATGTCAGACATTGAGGGAAGCTCTCATTGCTGCAGGAAAAGAGATTATATGGCATGGGCGGACA
AAAGAAGAACCAGCTCATTACTGTAGCATTTGTGAAGTGGAGGTTTTTGATCTGCTTTTTGTCACTAATGAGAGTAATTCACGAAAGACC
TACATAGTACATTGCCAAGATTGTGCACGAAAAACAAGCGGAAACTTGGAAAACTTTGTGGTGCTAGAACAGTACAAAATGGAGGACCTG
ATGCAAGTCTATGACCAATTTACATTAGCTCCTCCATTACCATCCGCCTCATCTTGATATTGTTCCATGGACATTAAATGAGACCTTTTC

>97776_97776_6_UTY-KDM6A_UTY_chrY_15470343_ENST00000545955_KDM6A_chrX_44920568_ENST00000382899_length(amino acids)=1428AA_BP=10
MKSCAVSLTTAAVAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFVRLHEDGARTKTLLGKAVRCYESLILKAEGKVES
DFFCQLGHFNLLLEDYSKALSAYQRYYSLQADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDY
KSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKATVLQQLGWMHHNMDLVGDKATKESYAIQYL
QKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYE
SCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQAQLCNLPQSSLQNKTKLLPSIEEAWSLPIPAELTSRQGAMNTAQQQSLSLHMITS
SQVEGLSSPAKKKRTSSPTKNTSDNWSGGHAVSHPPVQQQAHSWCLTPQKLQHLEQLRANRNNLNPAQKLMLEQLESQFVLMQQHQMRPT
GVAQVRSTGIPNGPTADSSLPTNSVSGQQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTLGSTDTILIGNNHITGSGS
NGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQSSHSAGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQG
AALNHLSSHTATSGGQQGITLTKESKPSGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSPGLLSSDNPQLSAL
LMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPKSTEQTTTNSVTSLNSPHSGLHTINGEGMEESQSPMKTDLLLV
NHKPSPQIIPSMSVSIYPSSAEVLKACRNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFCTNP
NNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKIWHCESNRSHTTIAKYAQYQASSFQESLREENEK
RSHHKDHSDSESTSSDNSGRRRKGPFKTIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHTILGMNTVQLYMKVPGSRT
PGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFCEKNNLNFLMGSWWPNLEDLYEANVPVYRFIQRPGDLVWINAGTVHWVQAIGW
CNNIAWNVGPLTACQYKLAVERYEWNKLQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIKYCLLRTLKQCQTLREALIAAGKEIIWHGRT

--------------------------------------------------------------
>97776_97776_7_UTY-KDM6A_UTY_chrY_15470343_ENST00000545955_KDM6A_chrX_44920568_ENST00000536777_length(transcript)=4384nt_BP=1410nt
ATGAAATCCTGCGCAGTGTCGCTCACTACCGCCGCTGTTGCCTTCGGTGATGAGGCAAAGAAAATGGCGGAAGGAAAAGCGAGCCGCGAG
AGTGAAGAGGAGTCTGTTAGCCTGACAGTCGAGGAAAGGGAGGCGCTTGGTGGCATGGACAGCCGTCTCTTCGGGTTCGTGAGGCTTCAT
GAAGATGGCGCCAGAACGAAGACCCTACTAGGCAAGGCTGTTCGCTGCTACGAATCTTTAATCTTAAAAGCTGAAGGAAAAGTGGAGTCT
GACTTCTTTTGCCAATTAGGTCACTTCAACCTCTTGTTGGAAGATTATTCAAAAGCATTATCTGCATATCAGAGATATTACAGTTTACAG
GCTGACTACTGGAAGAATGCTGCGTTTTTATATGGCCTTGGTTTGGTCTACTTCTACTACAATGCATTTCATTGGGCAATTAAAGCATTT
CAAGATGTCCTTTATGTTGACCCCAGCTTTTGTCGAGCCAAGGAAATTCATTTACGACTTGGGCTCATGTTCAAAGTGAACACAGACTAC
AAGTCTAGTTTAAAGCATTTTCAGTTAGCCTTGATTGACTGTAATCCATGTACTTTGTCCAATGCTGAAATTCAATTTCATATTGCCCAT
TTGTATGAAACCCAGAGGAAGTATCATTCTGCAAAGGAGGCATATGAACAACTTTTGCAGACAGAAAACCTTCCTGCACAAGTAAAAGCA
ACTGTATTGCAACAGTTAGGTTGGATGCATCATAATATGGATCTAGTAGGAGACAAAGCCACAAAGGAAAGCTATGCTATTCAGTATCTC
CAAAAGTCTTTGGAGGCAGATCCTAATTCTGGCCAATCGTGGTATTTTCTTGGAAGGTGTTATTCAAGTATTGGGAAAGTTCAGGATGCC
TTTATATCTTACAGGCAATCTATTGATAAATCAGAAGCAAGTGCAGATACATGGTGTTCAATAGGTGTGTTGTATCAGCAGCAAAATCAG
CCTATGGATGCTTTACAGGCATATATTTGTGCTGTACAATTGGACCATGGGCATGCCGCAGCCTGGATGGACCTAGGTACTCTCTATGAA
TCCTGCAATCAACCTCAAGATGCCATTAAATGCTACCTAAATGCAGCTAGAAGCAAACGTTGTAGTAATACCTCTACGCTTGCTGCAAGA
ATTAAATTTCTACAGGCTCAGTTGTGTAACCTTCCACAAAGTAGTCTACAGAATAAAACTAAATTACTTCCTAGTATTGAGGAGGCATGG
AGCCTACCAATCCCCGCAGAGCTTACCTCCAGGCAGGGTGCCATGAACACAGCACAGCAGCAATCCTTGTCACTACACATGATTACTTCT
AGCCAAGTAGAAGGCCTGTCCAGTCCTGCCAAGAAGAAAAGAACATCTAGTCCAACAAAGAATACTTCTGACAATTGGAGTGGTGGACAT
GCTGTGTCACATCCTCCAGTACAGCAACAAGCTCATTCATGGTGTTTGACACCACAGAAATTACAGCATTTGGAACAGCTCCGCGCAAAT
AGAAATAATTTAAATCCAGCACAGAAACTGATGCTGGAACAGCTGGAAAGTCAGTTTGTCTTAATGCAACAACACCAAATGAGACCAACA
GGAGTTGCACAGGTACGATCTACTGGAATTCCTAATGGGCCAACAGCTGACTCATCACTGCCTACAAACTCAGTCTCTGGCCAGCAGCCA
CAGCTTGCTCTGACCAGAGTGCCTAGCGTCTCTCAGCCTGGAGTCCGTCCTGCCTGCCCTGGGCAGCCTTTGGCCAATGGACCCTTTTCT
GCAGGCCATGTTCCCTGTAGCACATCAAGAACGCTGGGAAGTACAGACACTATTTTGATAGGCAATAATCATATAACAGGAAGTGGAAGT
AATGGAAACGTGCCTTACCTGCAGCGAAACGCACTCACTCTACCTCATAACCGCACAAACCTGACCAGCAGCGCAGAGGAGCCGTGGAAA
AACCAACTATCTAACTCCACTCAGGGGCTTCACAAAGGTCAGAGTTCACATTCGGCAGGTCCTAATGGTGAACGACCTCTCTCTTCCACT
GGGCCTTCCCAGCATCTCCAGGCAGCTGGCTCTGGTATTCAGAATCAGAACGGACATCCCACCCTGCCTAGCAATTCAGTAACACAGGGG
GCTGCTCTCAATCACCTCTCCTCTCACACTGCTACCTCAGGTGGACAACAAGGCATTACCTTAACCAAAGAGAGCAAGCCTTCAGGAAAC
ATATTGACGGTGCCTGAAACAAGCAGGCACACTGGAGAGACACCTAACAGCACTGCCAGTGTCGAGGGACTTCCTAATCATGTCCATCAG
ATGACGGCAGATGCTGTTTGCAGTCCTAGCCATGGAGATTCTAAGTCACCAGGTTTACTAAGTTCAGACAATCCTCAGCTCTCTGCCTTG
TTGATGGGAAAAGCCAATAACAATGTGGGTACTGGAACCTGTGACAAAGTCAATAACATCCACCCAGCTGTTCATACAAAGACTGATAAC
TCTGTTGCCTCTTCACCATCTTCAGCCATTTCAACAGCAACACCTTCTCCAAAATCCACTGAGCAGACAACCACAAACAGTGTTACCAGC
CTTAACAGCCCTCACAGTGGGCTACACACAATTAATGGAGAAGGGATGGAAGAATCTCAGAGCCCCATGAAAACAGATCTGCTTCTGGTT
AACCACAAACCTAGTCCACAGATCATACCATCAATGTCTGTGTCCATATACCCCAGCTCAGCAGAAGTTCTGAAGGCATGCAGGAATCTA
GGTAAAAATGGCTTATCTAACAGTAGCATTTTGTTGGATAAATGTCCACCTCCAAGACCACCATCTTCACCATACCCTCCCTTGCCAAAG
GACAAGTTGAATCCACCTACACCTAGTATTTACTTGGAAAATAAACGTGATGCTTTCTTTCCTCCATTACATCAATTTTGTACAAATCCG
AACAACCCTGTTACAGTAATACGTGGCCTTGCTGGAGCTCTTAAGTTAGACCTGGGACTTTTCTCTACTAAAACTTTGGTGGAAGCTAAC
AATGAACATATGGTAGAAGTGAGGACACAGTTGTTGCAGCCAGCAGATGAAAACTGGGATCCCACTGGAACAAAGAAAATCTGGCATTGT
GAAAGTAATAGATCTCATACTACAATTGCTAAATATGCACAGTACCAGGCCTCCTCATTCCAGGAATCATTGAGAGAAGAAAATGAAAAA
AGAAGTCATCATAAAGACCACTCAGATAGTGAATCTACATCGTCAGATAATTCTGGGAGGAGGAGGAAAGGACCCTTTAAAACCATAAAG
TTTGGGACCAATATTGACCTATCTGATGACAAAAAGTGGAAGTTGCAGCTACATGAGCTGACTAAACTTCCTGCTTTTGTGCGTGTCGTA
TCAGCAGGAAATCTTCTAAGCCATGTTGGTCATACCATATTGGGCATGAACACAGTTCAACTATACATGAAAGTTCCAGGGAGCAGAACA
CCAGGTCATCAGGAAAATAACAACTTCTGTTCAGTTAACATAAATATTGGCCCAGGTGACTGTGAATGGTTTGTTGTTCCTGAAGGTTAC
TGGGGTGTTCTGAATGACTTCTGTGAAAAAAATAATTTGAATTTCCTAATGGGTTCTTGGTGGCCCAATCTTGAAGATCTTTATGAAGCA
AATGTTCCAGTGTATAGGTTTATTCAGCGACCTGGAGATTTGGTCTGGATAAATGCAGGCACTGTTCATTGGGTTCAGGCTATTGGCTGG
TGCAACAACATTGCTTGGAATGTTGGTCCACTTACAGCCTGCCAGTATAAATTGGCAGTGGAACGGTACGAATGGAACAAATTGCAAAGT
GTGAAGTCAATAGTACCCATGGTTCATCTTTCCTGGAATATGGCACGAAATATCAAGGTCTCAGATCCAAAGCTTTTTGAAATGATTAAG
TATTGTCTTCTAAGAACTCTGAAGCAATGTCAGACATTGAGGGAAGCTCTCATTGCTGCAGGAAAAGAGATTATATGGCATGGGCGGACA
AAAGAAGAACCAGCTCATTACTGTAGCATTTGTGAAGTGGAGGTTTTTGATCTGCTTTTTGTCACTAATGAGAGTAATTCACGAAAGACC
TACATAGTACATTGCCAAGATTGTGCACGAAAAACAAGCGGAAACTTGGAAAACTTTGTGGTGCTAGAACAGTACAAAATGGAGGACCTG
ATGCAAGTCTATGACCAATTTACATTAGCTCCTCCATTACCATCCGCCTCATCTTGATATTGTTCCATGGACATTAAATGAGACCTTTTC

>97776_97776_7_UTY-KDM6A_UTY_chrY_15470343_ENST00000545955_KDM6A_chrX_44920568_ENST00000536777_length(amino acids)=1428AA_BP=10
MKSCAVSLTTAAVAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFVRLHEDGARTKTLLGKAVRCYESLILKAEGKVES
DFFCQLGHFNLLLEDYSKALSAYQRYYSLQADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDY
KSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKATVLQQLGWMHHNMDLVGDKATKESYAIQYL
QKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYE
SCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQAQLCNLPQSSLQNKTKLLPSIEEAWSLPIPAELTSRQGAMNTAQQQSLSLHMITS
SQVEGLSSPAKKKRTSSPTKNTSDNWSGGHAVSHPPVQQQAHSWCLTPQKLQHLEQLRANRNNLNPAQKLMLEQLESQFVLMQQHQMRPT
GVAQVRSTGIPNGPTADSSLPTNSVSGQQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTLGSTDTILIGNNHITGSGS
NGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQSSHSAGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQG
AALNHLSSHTATSGGQQGITLTKESKPSGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSPGLLSSDNPQLSAL
LMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPKSTEQTTTNSVTSLNSPHSGLHTINGEGMEESQSPMKTDLLLV
NHKPSPQIIPSMSVSIYPSSAEVLKACRNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFCTNP
NNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKIWHCESNRSHTTIAKYAQYQASSFQESLREENEK
RSHHKDHSDSESTSSDNSGRRRKGPFKTIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHTILGMNTVQLYMKVPGSRT
PGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFCEKNNLNFLMGSWWPNLEDLYEANVPVYRFIQRPGDLVWINAGTVHWVQAIGW
CNNIAWNVGPLTACQYKLAVERYEWNKLQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIKYCLLRTLKQCQTLREALIAAGKEIIWHGRT

--------------------------------------------------------------
>97776_97776_8_UTY-KDM6A_UTY_chrY_15470343_ENST00000545955_KDM6A_chrX_44920568_ENST00000543216_length(transcript)=4185nt_BP=1410nt
ATGAAATCCTGCGCAGTGTCGCTCACTACCGCCGCTGTTGCCTTCGGTGATGAGGCAAAGAAAATGGCGGAAGGAAAAGCGAGCCGCGAG
AGTGAAGAGGAGTCTGTTAGCCTGACAGTCGAGGAAAGGGAGGCGCTTGGTGGCATGGACAGCCGTCTCTTCGGGTTCGTGAGGCTTCAT
GAAGATGGCGCCAGAACGAAGACCCTACTAGGCAAGGCTGTTCGCTGCTACGAATCTTTAATCTTAAAAGCTGAAGGAAAAGTGGAGTCT
GACTTCTTTTGCCAATTAGGTCACTTCAACCTCTTGTTGGAAGATTATTCAAAAGCATTATCTGCATATCAGAGATATTACAGTTTACAG
GCTGACTACTGGAAGAATGCTGCGTTTTTATATGGCCTTGGTTTGGTCTACTTCTACTACAATGCATTTCATTGGGCAATTAAAGCATTT
CAAGATGTCCTTTATGTTGACCCCAGCTTTTGTCGAGCCAAGGAAATTCATTTACGACTTGGGCTCATGTTCAAAGTGAACACAGACTAC
AAGTCTAGTTTAAAGCATTTTCAGTTAGCCTTGATTGACTGTAATCCATGTACTTTGTCCAATGCTGAAATTCAATTTCATATTGCCCAT
TTGTATGAAACCCAGAGGAAGTATCATTCTGCAAAGGAGGCATATGAACAACTTTTGCAGACAGAAAACCTTCCTGCACAAGTAAAAGCA
ACTGTATTGCAACAGTTAGGTTGGATGCATCATAATATGGATCTAGTAGGAGACAAAGCCACAAAGGAAAGCTATGCTATTCAGTATCTC
CAAAAGTCTTTGGAGGCAGATCCTAATTCTGGCCAATCGTGGTATTTTCTTGGAAGGTGTTATTCAAGTATTGGGAAAGTTCAGGATGCC
TTTATATCTTACAGGCAATCTATTGATAAATCAGAAGCAAGTGCAGATACATGGTGTTCAATAGGTGTGTTGTATCAGCAGCAAAATCAG
CCTATGGATGCTTTACAGGCATATATTTGTGCTGTACAATTGGACCATGGGCATGCCGCAGCCTGGATGGACCTAGGTACTCTCTATGAA
TCCTGCAATCAACCTCAAGATGCCATTAAATGCTACCTAAATGCAGCTAGAAGCAAACGTTGTAGTAATACCTCTACGCTTGCTGCAAGA
ATTAAATTTCTACAGGCTCAGTTGTGTAACCTTCCACAAAGTAGTCTACAGAATAAAACTAAATTACTTCCTAGTATTGAGGAGGCATGG
AGCCTACCAATCCCCGCAGAGCTTACCTCCAGGCAGGGTGCCATGAACACAGCACAGCAGCAATCCTTGTCACTACACATGATTACTTCT
AGCCAAGTAGAAGGCCTGTCCAGTCCTGCCAAGAAGAAAAGAACATCTAGTCCAACAAAGAATACTTCTGACAATTGGAGTGGTGGACAT
GCTGTGTCACATCCTCCAGTACAGCAACAAGCTCATTCATGGTGTTTGACACCACAGAAATTACAGATGAGACCAACAGGAGTTGCACAG
GTACGATCTACTGGAATTCCTAATGGGCCAACAGCTGACTCATCACTGCCTACAAACTCAGTCTCTGGCCAGCAGCCACAGCTTGCTCTG
ACCAGAGTGCCTAGCGTCTCTCAGCCTGGAGTCCGTCCTGCCTGCCCTGGGCAGCCTTTGGCCAATGGACCCTTTTCTGCAGGCCATGTT
CCCTGTAGCACATCAAGAACGCTGGGAAGTACAGACACTATTTTGATAGGCAATAATCATATAACAGGAAGTGGAAGTAATGGAAACGTG
CCTTACCTGCAGCGAAACGCACTCACTCTACCTCATAACCGCACAAACCTGACCAGCAGCGCAGAGGAGCCGTGGAAAAACCAACTATCT
AACTCCACTCAGGGGCTTCACAAAGGTCAGAGTTCACATTCGGCAGGTCCTAATGGTGAACGACCTCTCTCTTCCACTGGGCCTTCCCAG
CATCTCCAGGCAGCTGGCTCTGGTATTCAGAATCAGAACGGACATCCCACCCTGCCTAGCAATTCAGTAACACAGGGGGCTGCTCTCAAT
CACCTCTCCTCTCACACTGCTACCTCAGGTGGACAACAAGGCATTACCTTAACCAAAGAGAGCAAGCCTTCAGGAAACATATTGACGGTG
CCTGAAACAAGCAGGCACACTGGAGAGACACCTAACAGCACTGCCAGTGTCGAGGGACTTCCTAATCATGTCCATCAGATGACGGCAGAT
GCTGTTTGCAGTCCTAGCCATGGAGATTCTAAGTCACCAGGTTTACTAAGTTCAGACAATCCTCAGCTCTCTGCCTTGTTGATGGGAAAA
GCCAATAACAATGTGGGTACTGGAACCTGTGACAAAGTCAATAACATCCACCCAGCTGTTCATACAAAGACTGATAACTCTGTTGCCTCT
TCACCATCTTCAGCCATTTCAACAGCAACACCTTCTCCAAAATCCACTGAGCAGACAACCACAAACAGTGTTACCAGCCTTAACAGCCCT
CACAGTGGGCTACACACAATTAATGGAGAAGGGATGGAAGAATCTCAGAGCCCCATGAAAACAGATCTGCTTCTGGTTAACCACAAACCT
AGTCCACAGATCATACCATCAATGTCTGTGTCCATATACCCCAGCTCAGCAGAAGTTCTGAAGGCATGCAGGAATCTAGGTAAAAATGGC
TTATCTAACAGTAGCATTTTGTTGGATAAATGTCCACCTCCAAGACCACCATCTTCACCATACCCTCCCTTGCCAAAGGACAAGTTGAAT
CCACCTACACCTAGTATTTACTTGGAAAATAAACGTGATGCTTTCTTTCCTCCATTACATCAATTTTGTACAAATCCGAACAACCCTGTT
ACAGTAATACGTGGCCTTGCTGGAGCTCTTAAGTTAGACCTGGGACTTTTCTCTACTAAAACTTTGGTGGAAGCTAACAATGAACATATG
GTAGAAGTGAGGACACAGTTGTTGCAGCCAGCAGATGAAAACTGGGATCCCACTGGAACAAAGAAAATCTGGCATTGTGAAAGTAATAGA
TCTCATACTACAATTGCTAAATATGCACAGTACCAGGCCTCCTCATTCCAGGAATCATTGAGAGAAGAAAATGAAAAAAGAAGTCATCAT
AAAGACCACTCAGATAGTGAATCTACATCGTCAGATAATTCTGGGAGGAGGAGGAAAGGACCCTTTAAAACCATAAAGTTTGGGACCAAT
ATTGACCTATCTGATGACAAAAAGTGGAAGTTGCAGCTACATGAGCTGACTAAACTTCCTGCTTTTGTGCGTGTCGTATCAGCAGGAAAT
CTTCTAAGCCATGTTGGTCATACCATATTGGGCATGAACACAGTTCAACTATACATGAAAGTTCCAGGGAGCAGAACACCAGGTCATCAG
GAAAATAACAACTTCTGTTCAGTTAACATAAATATTGGCCCAGGTGACTGTGAATGGTTTGTTGTTCCTGAAGGTTACTGGGGTGTTCTG
AATGACTTCTGTGAAAAAAATAATTTGAATTTCCTAATGGGTTCTTGGTGGCCCAATCTTGAAGATCTTTATGAAGCAAATGTTCCAGTG
TATAGGTTTATTCAGCGACCTGGAGATTTGGTCTGGATAAATGCAGGCACTGTTCATTGGGTTCAGGCTATTGGCTGGTGCAACAACATT
GCTTGGAATGTTGGTCCACTTACAGCCTGCCAGTATAAATTGGCAGTGGAACGGTACGAATGGAACAAATTGCAAAGTGTGAAGTCAATA
GTACCCATGGTTCATCTTTCCTGGAATATGGCACGAAATATCAAGGTCTCAGATCCAAAGCTTTTTGAAATGATTAAGTATTGTCTTCTA
AGAACTCTGAAGCAATGTCAGACATTGAGGGAAGCTCTCATTGCTGCAGGAAAAGAGATTATATGGCATGGGCGGACAAAAGAAGAACCA
GCTCATTACTGTAGCATTTGTGAAGTGGAGGTTTTTGATCTGCTTTTTGTCACTAATGAGAGTAATTCACGAAAGACCTACATAGTACAT
TGCCAAGATTGTGCACGAAAAACAAGCGGAAACTTGGAAAACTTTGTGGTGCTAGAACAGTACAAAATGGAGGACCTGATGCAAGTCTAT

>97776_97776_8_UTY-KDM6A_UTY_chrY_15470343_ENST00000545955_KDM6A_chrX_44920568_ENST00000543216_length(amino acids)=1394AA_BP=10
MKSCAVSLTTAAVAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFVRLHEDGARTKTLLGKAVRCYESLILKAEGKVES
DFFCQLGHFNLLLEDYSKALSAYQRYYSLQADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDY
KSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKATVLQQLGWMHHNMDLVGDKATKESYAIQYL
QKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYE
SCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQAQLCNLPQSSLQNKTKLLPSIEEAWSLPIPAELTSRQGAMNTAQQQSLSLHMITS
SQVEGLSSPAKKKRTSSPTKNTSDNWSGGHAVSHPPVQQQAHSWCLTPQKLQMRPTGVAQVRSTGIPNGPTADSSLPTNSVSGQQPQLAL
TRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTLGSTDTILIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLS
NSTQGLHKGQSSHSAGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHTATSGGQQGITLTKESKPSGNILTV
PETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVAS
SPSSAISTATPSPKSTEQTTTNSVTSLNSPHSGLHTINGEGMEESQSPMKTDLLLVNHKPSPQIIPSMSVSIYPSSAEVLKACRNLGKNG
LSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFCTNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHM
VEVRTQLLQPADENWDPTGTKKIWHCESNRSHTTIAKYAQYQASSFQESLREENEKRSHHKDHSDSESTSSDNSGRRRKGPFKTIKFGTN
IDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHTILGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVL
NDFCEKNNLNFLMGSWWPNLEDLYEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNVGPLTACQYKLAVERYEWNKLQSVKSI
VPMVHLSWNMARNIKVSDPKLFEMIKYCLLRTLKQCQTLREALIAAGKEIIWHGRTKEEPAHYCSICEVEVFDLLFVTNESNSRKTYIVH

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for UTY-KDM6A

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner	Gene	Hbp	Tbp	ENST	Strand	BPexon	TotalExon	Protein feature loci	*BPloci	TotalLen	Interaction lost with
Tgene	KDM6A	chrY:15470343	chrX:44920568	ENST00000377967		12	29	1_1095	443.0	1402.0	SUPT6H

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for UTY-KDM6A

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for UTY-KDM6A

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source