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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:UVRAG-ZMAT4 (FusionGDB2 ID:97822)

Fusion Gene Summary for UVRAG-ZMAT4

check button Fusion gene summary
Fusion gene informationFusion gene name: UVRAG-ZMAT4
Fusion gene ID: 97822
HgeneTgene
Gene symbol

UVRAG

ZMAT4

Gene ID

7405

79698

Gene nameUV radiation resistance associatedzinc finger matrin-type 4
SynonymsDHTX|VPS38|p63-
Cytomap

11q13.5

8p11.21

Type of geneprotein-codingprotein-coding
DescriptionUV radiation resistance-associated gene proteinbeclin 1 binding proteindisrupted in heterotaxyzinc finger matrin-type protein 4
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000356136, ENST00000528420, 
ENST00000531818, ENST00000532130, 
ENST00000533454, ENST00000539288, 
ENST00000525872, ENST00000538870, 
ENST00000523823, ENST00000297737, 
ENST00000315769, 
Fusion gene scores* DoF score41 X 18 X 15=1107015 X 12 X 7=1260
# samples 4917
** MAII scorelog2(49/11070*10)=-4.49772966266634
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(17/1260*10)=-2.88981708224958
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: UVRAG [Title/Abstract] AND ZMAT4 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointUVRAG(75728024)-ZMAT4(40389757), # samples:4
Anticipated loss of major functional domain due to fusion event.UVRAG-ZMAT4 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
UVRAG-ZMAT4 seems lost the major protein functional domain in Hgene partner, which is a tumor suppressor due to the frame-shifted ORF.
UVRAG-ZMAT4 seems lost the major protein functional domain in Tgene partner, which is a transcription factor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneUVRAG

GO:0071900

regulation of protein serine/threonine kinase activity

22542840

HgeneUVRAG

GO:0097352

autophagosome maturation

28306502

HgeneUVRAG

GO:0097680

double-strand break repair via classical nonhomologous end joining

22542840


check buttonFusion gene breakpoints across UVRAG (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ZMAT4 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-A2-A0ES-01AUVRAGchr11

75728024

-ZMAT4chr8

40389757

-
ChimerDB4BRCATCGA-A2-A0ES-01AUVRAGchr11

75728024

+ZMAT4chr8

40389757

-
ChimerDB4BRCATCGA-A2-A0ESUVRAGchr11

75728024

+ZMAT4chr8

40389757

-


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Fusion Gene ORF analysis for UVRAG-ZMAT4

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000356136ENST00000523823UVRAGchr11

75728024

+ZMAT4chr8

40389757

-
5CDS-intronENST00000528420ENST00000523823UVRAGchr11

75728024

+ZMAT4chr8

40389757

-
5CDS-intronENST00000531818ENST00000523823UVRAGchr11

75728024

+ZMAT4chr8

40389757

-
5CDS-intronENST00000532130ENST00000523823UVRAGchr11

75728024

+ZMAT4chr8

40389757

-
5CDS-intronENST00000533454ENST00000523823UVRAGchr11

75728024

+ZMAT4chr8

40389757

-
5CDS-intronENST00000539288ENST00000523823UVRAGchr11

75728024

+ZMAT4chr8

40389757

-
Frame-shiftENST00000356136ENST00000297737UVRAGchr11

75728024

+ZMAT4chr8

40389757

-
Frame-shiftENST00000528420ENST00000297737UVRAGchr11

75728024

+ZMAT4chr8

40389757

-
Frame-shiftENST00000531818ENST00000297737UVRAGchr11

75728024

+ZMAT4chr8

40389757

-
Frame-shiftENST00000532130ENST00000297737UVRAGchr11

75728024

+ZMAT4chr8

40389757

-
Frame-shiftENST00000533454ENST00000297737UVRAGchr11

75728024

+ZMAT4chr8

40389757

-
Frame-shiftENST00000539288ENST00000297737UVRAGchr11

75728024

+ZMAT4chr8

40389757

-
In-frameENST00000356136ENST00000315769UVRAGchr11

75728024

+ZMAT4chr8

40389757

-
In-frameENST00000528420ENST00000315769UVRAGchr11

75728024

+ZMAT4chr8

40389757

-
In-frameENST00000531818ENST00000315769UVRAGchr11

75728024

+ZMAT4chr8

40389757

-
In-frameENST00000532130ENST00000315769UVRAGchr11

75728024

+ZMAT4chr8

40389757

-
In-frameENST00000533454ENST00000315769UVRAGchr11

75728024

+ZMAT4chr8

40389757

-
In-frameENST00000539288ENST00000315769UVRAGchr11

75728024

+ZMAT4chr8

40389757

-
intron-3CDSENST00000525872ENST00000297737UVRAGchr11

75728024

+ZMAT4chr8

40389757

-
intron-3CDSENST00000525872ENST00000315769UVRAGchr11

75728024

+ZMAT4chr8

40389757

-
intron-3CDSENST00000538870ENST00000297737UVRAGchr11

75728024

+ZMAT4chr8

40389757

-
intron-3CDSENST00000538870ENST00000315769UVRAGchr11

75728024

+ZMAT4chr8

40389757

-
intron-intronENST00000525872ENST00000523823UVRAGchr11

75728024

+ZMAT4chr8

40389757

-
intron-intronENST00000538870ENST00000523823UVRAGchr11

75728024

+ZMAT4chr8

40389757

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000356136UVRAGchr1175728024+ENST00000315769ZMAT4chr840389757-311614671631482439
ENST00000528420UVRAGchr1175728024+ENST00000315769ZMAT4chr840389757-28571208961223375
ENST00000533454UVRAGchr1175728024+ENST00000315769ZMAT4chr840389757-251186221881733151
ENST00000531818UVRAGchr1175728024+ENST00000315769ZMAT4chr840389757-268910404471055202
ENST00000532130UVRAGchr1175728024+ENST00000315769ZMAT4chr840389757-223658748602184
ENST00000539288UVRAGchr1175728024+ENST00000315769ZMAT4chr840389757-230365419801525151

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000356136ENST00000315769UVRAGchr1175728024+ZMAT4chr840389757-0.0006027210.9993973
ENST00000528420ENST00000315769UVRAGchr1175728024+ZMAT4chr840389757-0.0007416770.99925834
ENST00000533454ENST00000315769UVRAGchr1175728024+ZMAT4chr840389757-0.69579490.30420512
ENST00000531818ENST00000315769UVRAGchr1175728024+ZMAT4chr840389757-0.72202620.2779738
ENST00000532130ENST00000315769UVRAGchr1175728024+ZMAT4chr840389757-0.72163780.27836218
ENST00000539288ENST00000315769UVRAGchr1175728024+ZMAT4chr840389757-0.45465220.5453478

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Fusion Genomic Features for UVRAG-ZMAT4


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for UVRAG-ZMAT4


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr11:75728024/chr8:40389757)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneUVRAGchr11:75728024chr8:40389757ENST00000356136+1215224_305408700.0Coiled coilOntology_term=ECO:0000255
HgeneUVRAGchr11:75728024chr8:40389757ENST00000356136+121523_149408700.0DomainC2
TgeneZMAT4chr11:75728024chr8:40389757ENST0000031576946198_228148154.0Zinc fingerNote=Matrin-type 4

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneZMAT4chr11:75728024chr8:40389757ENST0000029773757145_175224230.0Zinc fingerNote=Matrin-type 3
TgeneZMAT4chr11:75728024chr8:40389757ENST000002977375714_44224230.0Zinc fingerNote=Matrin-type 1
TgeneZMAT4chr11:75728024chr8:40389757ENST0000029773757198_228224230.0Zinc fingerNote=Matrin-type 4
TgeneZMAT4chr11:75728024chr8:40389757ENST000002977375772_106224230.0Zinc fingerNote=Matrin-type 2
TgeneZMAT4chr11:75728024chr8:40389757ENST0000031576946145_175148154.0Zinc fingerNote=Matrin-type 3
TgeneZMAT4chr11:75728024chr8:40389757ENST000003157694614_44148154.0Zinc fingerNote=Matrin-type 1
TgeneZMAT4chr11:75728024chr8:40389757ENST000003157694672_106148154.0Zinc fingerNote=Matrin-type 2


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Fusion Gene Sequence for UVRAG-ZMAT4


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>97822_97822_1_UVRAG-ZMAT4_UVRAG_chr11_75728024_ENST00000356136_ZMAT4_chr8_40389757_ENST00000315769_length(transcript)=3116nt_BP=1467nt
AATGAGCGCTCCGGGTCTCAGCGGGGTGGAGGGGTTGCACTGCGGTAATATGGCTCTTCCTTAGCCAGCGGCGGCAACGGCGGCAGCGGC
GGCAGCGGCGGCGGCTACTGTCTGGGCTGAGCAGTAGTGCCTCTCGGGTGGCGGGTTTCTAGGCTGCAGGGGCTTGGTAGGTGGTGGCAA
GGGGGCGGCGGCGGATGCCGGAAGAGTGCCCGCCCCGCCGCTTGGCGGCCCCTGGATCGAGATGAGCGCCTCCGCGTCGGTCGGGGGCCC
CGTCCCCCAGCCACCCCCGGGCCCGGCCGCTGCTCTGCCTCCCGGTTCTGCCGCGCGGGCCCTGCATGTGGAGCTGCCGTCTCAGCAGCG
GCGTCTTCGACATCTTCGGAACATTGCTGCCCGGAACATTGTTAATAGAAATGGCCATCAGCTCCTTGATACCTACTTTACACTTCACTT
GTGTAGTACTGAAAAGATATATAAAGAATTTTATAGAAGTGAAGTGATTAAGAATTCCTTGAATCCCACGTGGCGAAGTCTCGATTTTGG
AATTATGCCAGACCGTCTTGATACATCTGTGTCTTGTTTCGTGGTGAAGATATGGGGTGGAAAGGAGAACATCTACCAGCTGTTGATTGA
ATGGAAAGTCTGTTTGGATGGGCTGAAATACTTGGGTCAGCAGATTCATGCCCGAAACCAAAATGAAATAATTTTTGGGCTGAATGATGG
ATACTATGGTGCTCCATTTGAACATAAGGGTTATTCAAATGCTCAGAAGACTATTCTTCTGCAGGTGGATCAGAACTGTGTTCGCAATTC
TTACGATGTCTTCTCTTTGCTACGGCTTCATAGAGCCCAGTGTGCAATTAAACAGACTCAGGTAACTGTTCAGAAAATTGGAAAGGAAAT
TGAAGAAAAACTAAGACTCACATCTACAAGCAATGAACTGAAAAAAAAAAGTGAATGCCTGCAGTTAAAAATTTTGGTGCTTCAGAATGA
ACTGGAACGGCAGAAGAAAGCTTTGGGACGGGAGGTGGCATTACTGCATAAGCAACAAATTGCATTACAAGACAAAGGAAGTGCATTTTC
AGCTGAGCACCTCAAACTTCAACTCCAGAAGGAATCCCTAAATGAGCTGAGGAAGGAGTGCACTGCAAAAAGAGAACTCTTCTTGAAGAC
TAATGCTCAGTTGACAATTCGTTGCAGGCAGTTACTCTCTGAGCTTTCCTACATTTACCCTATTGATTTGAATGAACATAAGGATTACTT
TGTATGCGGTGTCAAGTTGCCTAATTCTGAGGACTTCCAAGCAAAAGATGATGGAAGCATTGCTGTTGCCCTTGGTTATACTGCACATCT
GGTCTCCATGATTTCCTTTTTCCTACAAGTGCCCCTCAGATATCCTATAATTCATAAGGGGTCTAGATCAACAATCAAAGACAATATCAA
TGACAAACTGACGGAAAAGGAGAGAGACCTGAAGAATAAGTAGTGAAAGCATCAATCAAGACATAAGAACAAAACATTAGCATTTCTCTG
CCGTGGAGAATTGCTTATCAACCACCAGAGGAGGCTTCTTTCTTGAACAATAAACATTTCTTATAAGGATTCACAGATTCACATACGACT
GATCTTGATTTTTGGAAATGAATGAGGTTTCTTTTTTCTTTTTCCTTTTTTTAATTTTGGGGTAAGTTATGATATTTGGATGGATTTTTA
AATTCTTTCCTGATAACATATTTAGCACATGTTCTAAATTATAATCCTATAGCAAACAGTTGGAGCATTATTCAAACTGAAAGTGGAAAA
ATTTAAATTTCCAATTTATTCTAGATTTCCTCAGAGCATAATTATTCTGTTAAATCCTCAATGAGTGTGATGTAAACCACCTCTATCCAG
AAATATACATTCTTTTCTCATCATGTTGGACACAGTTGAGGGTGACATGCACAGAACTGGAACAGATCACTATTAGTGGAAAATACCAAA
TGGACAAATAAATACCAGTCGTTTTCTCCGTTCTCCAAGCACAGGAGCCAGGTTTACCATCTGAACAATGAAGACGAAGGGAGTAAATAA
AGGAAGAATTCTCATCTTTTTTCCTGATCATTCAAAGAACAGTTTCTCAAGGTTAAGCCAAGTCCTCCTTGCAAGTTGCCAAATAATAGC
TTAGGAAAAGAATTAGTCTGCCTGCATGATGATCTTCTTAGGCAAAAACGTCTTCACAGCCCTTGACCTTGGTGAATTTTTTTCCCCAAA
AGCATCCAAAAGAAGAATTATAAACCCCAGAATGAGATGGAAATAAACAAGTATTTTTTTTTATGATGTTTGGCCTGAACTGTGGGCTTT
AATTGGGGGATACTGATCGTTTGGAAAGAAGTGAGAAAATTCTGAAGAAATGGCGGCCTTGGGCTAGGCGGGGTCCCCTATTTCTTCTGT
TTCTCACTGAAGTCCTACTGCTGAGCCAAGACTCAGTCACTCTGGAAAGAGCATGACCGATAAAGAAAACAGTTCCTTTCTGATGGGGAG
CGTCTGAGTGCAGATCATGAGGCTCTTTCTCTAGGTTTAATTCTTTTCCATGGTGACCGGACTTGGTGTCTTGTAGCCTGGTTACGAAGT
GGGACGTTGAGCTTCTACTGACGATGCCCTGCATGGACCAGCTGGGATCTGGCTGGGGCTGCCCTGTGTCCCTAACGACCATAGGCAATC
CATCTTCTTGTGTCAGCAATTTCTGGACACCCACTGTTTTCCACCAAGAGCTGAGGTGGCAACAACTCAGTGAGCAATAAACAAAATGAC
ACAGAAATGCACAGTGTTGTTATGAAGGAGCCTGTTTACCTGTGTTCAAAATCTGGCACCATTCCCTTGAGCAGGGCCCGCTCAGGAGGG
ACCAGGTCTGCCAGTTTCTGTGCCTGCAGAGAGACGAAGCCCCACGAGCCACACCCTACTCTACAAGAGGAAAGGGGGTTGGATGGGAAG
AATCTATTTTGCTGTTTTGGAAAGCACACAGCCGACCTACAAACCTCCTGTGATGGTGTTTCTTCGGATGTGTAAAATAAGGCTTTATTT

>97822_97822_1_UVRAG-ZMAT4_UVRAG_chr11_75728024_ENST00000356136_ZMAT4_chr8_40389757_ENST00000315769_length(amino acids)=439AA_BP=
MVGGGKGAAADAGRVPAPPLGGPWIEMSASASVGGPVPQPPPGPAAALPPGSAARALHVELPSQQRRLRHLRNIAARNIVNRNGHQLLDT
YFTLHLCSTEKIYKEFYRSEVIKNSLNPTWRSLDFGIMPDRLDTSVSCFVVKIWGGKENIYQLLIEWKVCLDGLKYLGQQIHARNQNEII
FGLNDGYYGAPFEHKGYSNAQKTILLQVDQNCVRNSYDVFSLLRLHRAQCAIKQTQVTVQKIGKEIEEKLRLTSTSNELKKKSECLQLKI
LVLQNELERQKKALGREVALLHKQQIALQDKGSAFSAEHLKLQLQKESLNELRKECTAKRELFLKTNAQLTIRCRQLLSELSYIYPIDLN

--------------------------------------------------------------
>97822_97822_2_UVRAG-ZMAT4_UVRAG_chr11_75728024_ENST00000528420_ZMAT4_chr8_40389757_ENST00000315769_length(transcript)=2857nt_BP=1208nt
AGTGCTCAGCTCCCTTGCCATGCGATACCCTGCAAGTCCTCACCAGCAAAAAGGCTCTCACCAGAGGCTGCCCCTCGGCCTGTGTTATCA
GATTTTTTGCGGCGTCTTCGACATCTTCGGAACATTGCTGCCCGGAACATTGTTAATAGAAATGGCCATCAGCTCCTTGATACCTACTTT
ACACTTCACTTGTGTAGTACTGAAAAGATATATAAAGAATTTTATAGAAGTGAAGTGATTAAGAATTCCTTGAATCCCACGTGGCGAAGT
CTCGATTTTGGAATTATGCCAGACCGTCTTGATACATCTGTGTCTTGTTTCGTGGTGAAGATATGGGGTGGAAAGGAGAACATCTACCAG
CTGTTGATTGAATGGAAAGTCTGTTTGGATGGGCTGAAATACTTGGGTCAGCAGATTCATGCCCGAAACCAAAATGAAATAATTTTTGGG
CTGAATGATGGATACTATGGTGCTCCATTTGAACATAAGGGTTATTCAAATGCTCAGAAGACTATTCTTCTGCAGGTGGATCAGAACTGT
GTTCGCAATTCTTACGATGTCTTCTCTTTGCTACGGCTTCATAGAGCCCAGTGTGCAATTAAACAGACTCAGGTAACTGTTCAGAAAATT
GGAAAGGAAATTGAAGAAAAACTAAGACTCACATCTACAAGCAATGAACTGAAAAAAAAAAGTGAATGCCTGCAGTTAAAAATTTTGGTG
CTTCAGAATGAACTGGAACGGCAGAAGAAAGCTTTGGGACGGGAGGTGGCATTACTGCATAAGCAACAAATTGCATTACAAGACAAAGGA
AGTGCATTTTCAGCTGAGCACCTCAAACTTCAACTCCAGAAGGAATCCCTAAATGAGCTGAGGAAGGAGTGCACTGCAAAAAGAGAACTC
TTCTTGAAGACTAATGCTCAGTTGACAATTCGTTGCAGGCAGTTACTCTCTGAGCTTTCCTACATTTACCCTATTGATTTGAATGAACAT
AAGGATTACTTTGTATGCGGTGTCAAGTTGCCTAATTCTGAGGACTTCCAAGCAAAAGATGATGGAAGCATTGCTGTTGCCCTTGGTTAT
ACTGCACATCTGGTCTCCATGATTTCCTTTTTCCTACAAGTGCCCCTCAGATATCCTATAATTCATAAGGGGTCTAGATCAACAATCAAA
GACAATATCAATGACAAACTGACGGAAAAGGAGAGAGACCTGAAGAATAAGTAGTGAAAGCATCAATCAAGACATAAGAACAAAACATTA
GCATTTCTCTGCCGTGGAGAATTGCTTATCAACCACCAGAGGAGGCTTCTTTCTTGAACAATAAACATTTCTTATAAGGATTCACAGATT
CACATACGACTGATCTTGATTTTTGGAAATGAATGAGGTTTCTTTTTTCTTTTTCCTTTTTTTAATTTTGGGGTAAGTTATGATATTTGG
ATGGATTTTTAAATTCTTTCCTGATAACATATTTAGCACATGTTCTAAATTATAATCCTATAGCAAACAGTTGGAGCATTATTCAAACTG
AAAGTGGAAAAATTTAAATTTCCAATTTATTCTAGATTTCCTCAGAGCATAATTATTCTGTTAAATCCTCAATGAGTGTGATGTAAACCA
CCTCTATCCAGAAATATACATTCTTTTCTCATCATGTTGGACACAGTTGAGGGTGACATGCACAGAACTGGAACAGATCACTATTAGTGG
AAAATACCAAATGGACAAATAAATACCAGTCGTTTTCTCCGTTCTCCAAGCACAGGAGCCAGGTTTACCATCTGAACAATGAAGACGAAG
GGAGTAAATAAAGGAAGAATTCTCATCTTTTTTCCTGATCATTCAAAGAACAGTTTCTCAAGGTTAAGCCAAGTCCTCCTTGCAAGTTGC
CAAATAATAGCTTAGGAAAAGAATTAGTCTGCCTGCATGATGATCTTCTTAGGCAAAAACGTCTTCACAGCCCTTGACCTTGGTGAATTT
TTTTCCCCAAAAGCATCCAAAAGAAGAATTATAAACCCCAGAATGAGATGGAAATAAACAAGTATTTTTTTTTATGATGTTTGGCCTGAA
CTGTGGGCTTTAATTGGGGGATACTGATCGTTTGGAAAGAAGTGAGAAAATTCTGAAGAAATGGCGGCCTTGGGCTAGGCGGGGTCCCCT
ATTTCTTCTGTTTCTCACTGAAGTCCTACTGCTGAGCCAAGACTCAGTCACTCTGGAAAGAGCATGACCGATAAAGAAAACAGTTCCTTT
CTGATGGGGAGCGTCTGAGTGCAGATCATGAGGCTCTTTCTCTAGGTTTAATTCTTTTCCATGGTGACCGGACTTGGTGTCTTGTAGCCT
GGTTACGAAGTGGGACGTTGAGCTTCTACTGACGATGCCCTGCATGGACCAGCTGGGATCTGGCTGGGGCTGCCCTGTGTCCCTAACGAC
CATAGGCAATCCATCTTCTTGTGTCAGCAATTTCTGGACACCCACTGTTTTCCACCAAGAGCTGAGGTGGCAACAACTCAGTGAGCAATA
AACAAAATGACACAGAAATGCACAGTGTTGTTATGAAGGAGCCTGTTTACCTGTGTTCAAAATCTGGCACCATTCCCTTGAGCAGGGCCC
GCTCAGGAGGGACCAGGTCTGCCAGTTTCTGTGCCTGCAGAGAGACGAAGCCCCACGAGCCACACCCTACTCTACAAGAGGAAAGGGGGT
TGGATGGGAAGAATCTATTTTGCTGTTTTGGAAAGCACACAGCCGACCTACAAACCTCCTGTGATGGTGTTTCTTCGGATGTGTAAAATA

>97822_97822_2_UVRAG-ZMAT4_UVRAG_chr11_75728024_ENST00000528420_ZMAT4_chr8_40389757_ENST00000315769_length(amino acids)=375AA_BP=
MRRLRHLRNIAARNIVNRNGHQLLDTYFTLHLCSTEKIYKEFYRSEVIKNSLNPTWRSLDFGIMPDRLDTSVSCFVVKIWGGKENIYQLL
IEWKVCLDGLKYLGQQIHARNQNEIIFGLNDGYYGAPFEHKGYSNAQKTILLQVDQNCVRNSYDVFSLLRLHRAQCAIKQTQVTVQKIGK
EIEEKLRLTSTSNELKKKSECLQLKILVLQNELERQKKALGREVALLHKQQIALQDKGSAFSAEHLKLQLQKESLNELRKECTAKRELFL
KTNAQLTIRCRQLLSELSYIYPIDLNEHKDYFVCGVKLPNSEDFQAKDDGSIAVALGYTAHLVSMISFFLQVPLRYPIIHKGSRSTIKDN

--------------------------------------------------------------
>97822_97822_3_UVRAG-ZMAT4_UVRAG_chr11_75728024_ENST00000531818_ZMAT4_chr8_40389757_ENST00000315769_length(transcript)=2689nt_BP=1040nt
CAGTTCGAGCTTCTGGGCAGCTTTGTTTACCTGCTCAAGCCTCAGCATTGGTGGGCGCCCCTCCCCCAGCCTCGCTGCCGCCTTGCAGTT
TGATCTCAGACTGCTGTGCTAGCAGTGAGCAAGGCTCCGTGGGCGTGGGACCCTCTGAGCCAGGCGCGGGATATAATCTTCTGGTATGCT
GTTTGCTAAGACCTTTGGAAAAGCACAGTATTAGGGTGGGAGTGACCTGATTTTCCGGGTGCGATTTTCCAGGTGCCGTCTGTCGTGGCT
TCCCTTGGCTGGGAAAGGGAGTTCCCCGACCCCTTGTGCTTCCCTGGTGAGGCGATGCCTTGCCCTGCTTTGGCTCACGGTCCGTGGGCT
GCACCCACTGTCCTACAAGCCCCAGTGAGATGAACCCGGCACCTCAATTGGAAATGCAGAAATCATCCATCTTCTGCGTCGCTCACGCTG
GAAGCTGTAGACTGGAGCTATTCCTATTCGGCCATCTTGGAACCTCCCTGCCTCTTTTTTCTGAAAAAAAAAAGTGAATGCCTGCAGTTA
AAAATTTTGGTGCTTCAGAATGAACTGGAACGGCAGAAGAAAGCTTTGGGACGGGAGGTGGCATTACTGCATAAGCAACAAATTGCATTA
CAAGACAAAGGAAGTGCATTTTCAGCTGAGCACCTCAAACTTCAACTCCAGAAGGAATCCCTAAATGAGCTGAGGAAGGAGTGCACTGCA
AAAAGAGAACTCTTCTTGAAGACTAATGCTCAGTTGACAATTCGTTGCAGGCAGTTACTCTCTGAGCTTTCCTACATTTACCCTATTGAT
TTGAATGAACATAAGGATTACTTTGTATGCGGTGTCAAGTTGCCTAATTCTGAGGACTTCCAAGCAAAAGATGATGGAAGCATTGCTGTT
GCCCTTGGTTATACTGCACATCTGGTCTCCATGATTTCCTTTTTCCTACAAGTGCCCCTCAGATATCCTATAATTCATAAGGGGTCTAGA
TCAACAATCAAAGACAATATCAATGACAAACTGACGGAAAAGGAGAGAGACCTGAAGAATAAGTAGTGAAAGCATCAATCAAGACATAAG
AACAAAACATTAGCATTTCTCTGCCGTGGAGAATTGCTTATCAACCACCAGAGGAGGCTTCTTTCTTGAACAATAAACATTTCTTATAAG
GATTCACAGATTCACATACGACTGATCTTGATTTTTGGAAATGAATGAGGTTTCTTTTTTCTTTTTCCTTTTTTTAATTTTGGGGTAAGT
TATGATATTTGGATGGATTTTTAAATTCTTTCCTGATAACATATTTAGCACATGTTCTAAATTATAATCCTATAGCAAACAGTTGGAGCA
TTATTCAAACTGAAAGTGGAAAAATTTAAATTTCCAATTTATTCTAGATTTCCTCAGAGCATAATTATTCTGTTAAATCCTCAATGAGTG
TGATGTAAACCACCTCTATCCAGAAATATACATTCTTTTCTCATCATGTTGGACACAGTTGAGGGTGACATGCACAGAACTGGAACAGAT
CACTATTAGTGGAAAATACCAAATGGACAAATAAATACCAGTCGTTTTCTCCGTTCTCCAAGCACAGGAGCCAGGTTTACCATCTGAACA
ATGAAGACGAAGGGAGTAAATAAAGGAAGAATTCTCATCTTTTTTCCTGATCATTCAAAGAACAGTTTCTCAAGGTTAAGCCAAGTCCTC
CTTGCAAGTTGCCAAATAATAGCTTAGGAAAAGAATTAGTCTGCCTGCATGATGATCTTCTTAGGCAAAAACGTCTTCACAGCCCTTGAC
CTTGGTGAATTTTTTTCCCCAAAAGCATCCAAAAGAAGAATTATAAACCCCAGAATGAGATGGAAATAAACAAGTATTTTTTTTTATGAT
GTTTGGCCTGAACTGTGGGCTTTAATTGGGGGATACTGATCGTTTGGAAAGAAGTGAGAAAATTCTGAAGAAATGGCGGCCTTGGGCTAG
GCGGGGTCCCCTATTTCTTCTGTTTCTCACTGAAGTCCTACTGCTGAGCCAAGACTCAGTCACTCTGGAAAGAGCATGACCGATAAAGAA
AACAGTTCCTTTCTGATGGGGAGCGTCTGAGTGCAGATCATGAGGCTCTTTCTCTAGGTTTAATTCTTTTCCATGGTGACCGGACTTGGT
GTCTTGTAGCCTGGTTACGAAGTGGGACGTTGAGCTTCTACTGACGATGCCCTGCATGGACCAGCTGGGATCTGGCTGGGGCTGCCCTGT
GTCCCTAACGACCATAGGCAATCCATCTTCTTGTGTCAGCAATTTCTGGACACCCACTGTTTTCCACCAAGAGCTGAGGTGGCAACAACT
CAGTGAGCAATAAACAAAATGACACAGAAATGCACAGTGTTGTTATGAAGGAGCCTGTTTACCTGTGTTCAAAATCTGGCACCATTCCCT
TGAGCAGGGCCCGCTCAGGAGGGACCAGGTCTGCCAGTTTCTGTGCCTGCAGAGAGACGAAGCCCCACGAGCCACACCCTACTCTACAAG
AGGAAAGGGGGTTGGATGGGAAGAATCTATTTTGCTGTTTTGGAAAGCACACAGCCGACCTACAAACCTCCTGTGATGGTGTTTCTTCGG

>97822_97822_3_UVRAG-ZMAT4_UVRAG_chr11_75728024_ENST00000531818_ZMAT4_chr8_40389757_ENST00000315769_length(amino acids)=202AA_BP=
MEAVDWSYSYSAILEPPCLFFLKKKSECLQLKILVLQNELERQKKALGREVALLHKQQIALQDKGSAFSAEHLKLQLQKESLNELRKECT
AKRELFLKTNAQLTIRCRQLLSELSYIYPIDLNEHKDYFVCGVKLPNSEDFQAKDDGSIAVALGYTAHLVSMISFFLQVPLRYPIIHKGS

--------------------------------------------------------------
>97822_97822_4_UVRAG-ZMAT4_UVRAG_chr11_75728024_ENST00000532130_ZMAT4_chr8_40389757_ENST00000315769_length(transcript)=2236nt_BP=587nt
TTTAGTAGAATTCACTGTGAAACCAACTAGACCTTTTTTTTTTCTCCCCTGTTTCTGAAGAAAAAAAAAAGTGAATGCCTGCAGTTAAAA
ATTTTGGTGCTTCAGAATGAACTGGAACGGCAGAAGAAAGCTTTGGGACGGGAGGTGGCATTACTGCATAAGCAACAAATTGCATTACAA
GACAAAGGAAGTGCATTTTCAGCTGAGCACCTCAAACTTCAACTCCAGAAGGAATCCCTAAATGAGCTGAGGAAGGAGTGCACTGCAAAA
AGAGAACTCTTCTTGAAGACTAATGCTCAGTTGACAATTCGTTGCAGGCAGTTACTCTCTGAGCTTTCCTACATTTACCCTATTGATTTG
AATGAACATAAGGATTACTTTGTATGCGGTGTCAAGTTGCCTAATTCTGAGGACTTCCAAGCAAAAGATGATGGAAGCATTGCTGTTGCC
CTTGGTTATACTGCACATCTGGTCTCCATGATTTCCTTTTTCCTACAAGTGCCCCTCAGATATCCTATAATTCATAAGGGGTCTAGATCA
ACAATCAAAGACAATATCAATGACAAACTGACGGAAAAGGAGAGAGACCTGAAGAATAAGTAGTGAAAGCATCAATCAAGACATAAGAAC
AAAACATTAGCATTTCTCTGCCGTGGAGAATTGCTTATCAACCACCAGAGGAGGCTTCTTTCTTGAACAATAAACATTTCTTATAAGGAT
TCACAGATTCACATACGACTGATCTTGATTTTTGGAAATGAATGAGGTTTCTTTTTTCTTTTTCCTTTTTTTAATTTTGGGGTAAGTTAT
GATATTTGGATGGATTTTTAAATTCTTTCCTGATAACATATTTAGCACATGTTCTAAATTATAATCCTATAGCAAACAGTTGGAGCATTA
TTCAAACTGAAAGTGGAAAAATTTAAATTTCCAATTTATTCTAGATTTCCTCAGAGCATAATTATTCTGTTAAATCCTCAATGAGTGTGA
TGTAAACCACCTCTATCCAGAAATATACATTCTTTTCTCATCATGTTGGACACAGTTGAGGGTGACATGCACAGAACTGGAACAGATCAC
TATTAGTGGAAAATACCAAATGGACAAATAAATACCAGTCGTTTTCTCCGTTCTCCAAGCACAGGAGCCAGGTTTACCATCTGAACAATG
AAGACGAAGGGAGTAAATAAAGGAAGAATTCTCATCTTTTTTCCTGATCATTCAAAGAACAGTTTCTCAAGGTTAAGCCAAGTCCTCCTT
GCAAGTTGCCAAATAATAGCTTAGGAAAAGAATTAGTCTGCCTGCATGATGATCTTCTTAGGCAAAAACGTCTTCACAGCCCTTGACCTT
GGTGAATTTTTTTCCCCAAAAGCATCCAAAAGAAGAATTATAAACCCCAGAATGAGATGGAAATAAACAAGTATTTTTTTTTATGATGTT
TGGCCTGAACTGTGGGCTTTAATTGGGGGATACTGATCGTTTGGAAAGAAGTGAGAAAATTCTGAAGAAATGGCGGCCTTGGGCTAGGCG
GGGTCCCCTATTTCTTCTGTTTCTCACTGAAGTCCTACTGCTGAGCCAAGACTCAGTCACTCTGGAAAGAGCATGACCGATAAAGAAAAC
AGTTCCTTTCTGATGGGGAGCGTCTGAGTGCAGATCATGAGGCTCTTTCTCTAGGTTTAATTCTTTTCCATGGTGACCGGACTTGGTGTC
TTGTAGCCTGGTTACGAAGTGGGACGTTGAGCTTCTACTGACGATGCCCTGCATGGACCAGCTGGGATCTGGCTGGGGCTGCCCTGTGTC
CCTAACGACCATAGGCAATCCATCTTCTTGTGTCAGCAATTTCTGGACACCCACTGTTTTCCACCAAGAGCTGAGGTGGCAACAACTCAG
TGAGCAATAAACAAAATGACACAGAAATGCACAGTGTTGTTATGAAGGAGCCTGTTTACCTGTGTTCAAAATCTGGCACCATTCCCTTGA
GCAGGGCCCGCTCAGGAGGGACCAGGTCTGCCAGTTTCTGTGCCTGCAGAGAGACGAAGCCCCACGAGCCACACCCTACTCTACAAGAGG
AAAGGGGGTTGGATGGGAAGAATCTATTTTGCTGTTTTGGAAAGCACACAGCCGACCTACAAACCTCCTGTGATGGTGTTTCTTCGGATG

>97822_97822_4_UVRAG-ZMAT4_UVRAG_chr11_75728024_ENST00000532130_ZMAT4_chr8_40389757_ENST00000315769_length(amino acids)=184AA_BP=
MFLKKKKSECLQLKILVLQNELERQKKALGREVALLHKQQIALQDKGSAFSAEHLKLQLQKESLNELRKECTAKRELFLKTNAQLTIRCR
QLLSELSYIYPIDLNEHKDYFVCGVKLPNSEDFQAKDDGSIAVALGYTAHLVSMISFFLQVPLRYPIIHKGSRSTIKDNINDKLTEKERD

--------------------------------------------------------------
>97822_97822_5_UVRAG-ZMAT4_UVRAG_chr11_75728024_ENST00000533454_ZMAT4_chr8_40389757_ENST00000315769_length(transcript)=2511nt_BP=862nt
ACTACCCACAAGAGGTGGTGAAAACGATCTCTGGTATAAAGCAAATGGAAAAGGCTTCATAGAGCCCAGTGTGCAATTAAACAGACTCAG
GTAACTGTTCAGAAAATTGGAAAGGAAATTGAAGAAAAACTAAGACTCACATCTACAAGCAATGAACTGAAAAAAAAAAGTGAATGCCTG
CAGTTAAAAATTTTGGTGCTTCAGAATGAACTGGAACGGCAGAAGAAAGCTTTGGGACGGGAGGTGGCATTACTGCATAAGCAACAAATT
GCATTACAAGACAAAGGAAGTGCATTTTCAGCTGAGCACCTCAAACTTCAACTCCAGAAGGAATCCCTAAATGAGCTGAGGAAGGAGTGC
ACTGCAAAAAGAGAACTCTTCTTGAAGACTAATGCTCAGTTGACAATTCGTTGCAGGCAGTTACTCTCTGAGCTTTCCTACATTTACCCT
ATTGATTTGAATGAACATAAGGATTACTTTGTATGCGGTGTCAAGTTGCCTAATTCTGAGGACTTCCAAGGCATGATTTCTTGGAAAGGA
GAGTCCATATGTCAAACAATGTCTCATTGAGAACATGGAATGATTCCATAGATGCTGTGGCAGTGATTAGAGTCTTAAATATTTTGTCCT
GTCTGGATCAGTGGGTGCTTGGTTCCTTAACAAATCAGCTGCCTCAGTGATTGGGAAGGCAGGATGCAAAAGATGATGGAAGCATTGCTG
TTGCCCTTGGTTATACTGCACATCTGGTCTCCATGATTTCCTTTTTCCTACAAGTGCCCCTCAGATATCCTATAATTCATAAGGGGTCTA
GATCAACAATCAAAGACAATATCAATGACAAACTGACGGAAAAGGAGAGAGACCTGAAGAATAAGTAGTGAAAGCATCAATCAAGACATA
AGAACAAAACATTAGCATTTCTCTGCCGTGGAGAATTGCTTATCAACCACCAGAGGAGGCTTCTTTCTTGAACAATAAACATTTCTTATA
AGGATTCACAGATTCACATACGACTGATCTTGATTTTTGGAAATGAATGAGGTTTCTTTTTTCTTTTTCCTTTTTTTAATTTTGGGGTAA
GTTATGATATTTGGATGGATTTTTAAATTCTTTCCTGATAACATATTTAGCACATGTTCTAAATTATAATCCTATAGCAAACAGTTGGAG
CATTATTCAAACTGAAAGTGGAAAAATTTAAATTTCCAATTTATTCTAGATTTCCTCAGAGCATAATTATTCTGTTAAATCCTCAATGAG
TGTGATGTAAACCACCTCTATCCAGAAATATACATTCTTTTCTCATCATGTTGGACACAGTTGAGGGTGACATGCACAGAACTGGAACAG
ATCACTATTAGTGGAAAATACCAAATGGACAAATAAATACCAGTCGTTTTCTCCGTTCTCCAAGCACAGGAGCCAGGTTTACCATCTGAA
CAATGAAGACGAAGGGAGTAAATAAAGGAAGAATTCTCATCTTTTTTCCTGATCATTCAAAGAACAGTTTCTCAAGGTTAAGCCAAGTCC
TCCTTGCAAGTTGCCAAATAATAGCTTAGGAAAAGAATTAGTCTGCCTGCATGATGATCTTCTTAGGCAAAAACGTCTTCACAGCCCTTG
ACCTTGGTGAATTTTTTTCCCCAAAAGCATCCAAAAGAAGAATTATAAACCCCAGAATGAGATGGAAATAAACAAGTATTTTTTTTTATG
ATGTTTGGCCTGAACTGTGGGCTTTAATTGGGGGATACTGATCGTTTGGAAAGAAGTGAGAAAATTCTGAAGAAATGGCGGCCTTGGGCT
AGGCGGGGTCCCCTATTTCTTCTGTTTCTCACTGAAGTCCTACTGCTGAGCCAAGACTCAGTCACTCTGGAAAGAGCATGACCGATAAAG
AAAACAGTTCCTTTCTGATGGGGAGCGTCTGAGTGCAGATCATGAGGCTCTTTCTCTAGGTTTAATTCTTTTCCATGGTGACCGGACTTG
GTGTCTTGTAGCCTGGTTACGAAGTGGGACGTTGAGCTTCTACTGACGATGCCCTGCATGGACCAGCTGGGATCTGGCTGGGGCTGCCCT
GTGTCCCTAACGACCATAGGCAATCCATCTTCTTGTGTCAGCAATTTCTGGACACCCACTGTTTTCCACCAAGAGCTGAGGTGGCAACAA
CTCAGTGAGCAATAAACAAAATGACACAGAAATGCACAGTGTTGTTATGAAGGAGCCTGTTTACCTGTGTTCAAAATCTGGCACCATTCC
CTTGAGCAGGGCCCGCTCAGGAGGGACCAGGTCTGCCAGTTTCTGTGCCTGCAGAGAGACGAAGCCCCACGAGCCACACCCTACTCTACA
AGAGGAAAGGGGGTTGGATGGGAAGAATCTATTTTGCTGTTTTGGAAAGCACACAGCCGACCTACAAACCTCCTGTGATGGTGTTTCTTC

>97822_97822_5_UVRAG-ZMAT4_UVRAG_chr11_75728024_ENST00000533454_ZMAT4_chr8_40389757_ENST00000315769_length(amino acids)=151AA_BP=
MCHFVYCSLSCCHLSSWWKTVGVQKLLTQEDGLPMVVRDTGQPQPDPSWSMQGIVSRSSTSHFVTRLQDTKSGHHGKELNLEKEPHDLHS

--------------------------------------------------------------
>97822_97822_6_UVRAG-ZMAT4_UVRAG_chr11_75728024_ENST00000539288_ZMAT4_chr8_40389757_ENST00000315769_length(transcript)=2303nt_BP=654nt
AACTGGAACGGCAGAAGAAAGCTTTGGGACGGGAGGTGGCATTACTGCATAAGCAACAAATTGCATTACAAGACAAAGGAAGTGCATTTT
CAGCTGAGCACCTCAAACTTCAACTCCAGAAGGAATCCCTAAATGAGCTGAGGAAGGAGTGCACTGCAAAAAGAGAACTCTTCTTGAAGA
CTAATGCTCAGTTGACAATTCGTTGCAGGCAGTTACTCTCTGAGCTTTCCTACATTTACCCTATTGATTTGAATGAACATAAGGATTACT
TTGTATGCGGTGTCAAGTTGCCTAATTCTGAGGACTTCCAAGGCATGATTTCTTGGAAAGGAGAGTCCATATGTCAAACAATGTCTCATT
GAGAACATGGAATGATTCCATAGATGCTGTGGCAGTGATTAGAGTCTTAAATATTTTGTCCTGTCTGGATCAGTGGGTGCTTGGTTCCTT
AACAAATCAGCTGCCTCAGTGATTGGGAAGGCAGGATGCAAAAGATGATGGAAGCATTGCTGTTGCCCTTGGTTATACTGCACATCTGGT
CTCCATGATTTCCTTTTTCCTACAAGTGCCCCTCAGATATCCTATAATTCATAAGGGGTCTAGATCAACAATCAAAGACAATATCAATGA
CAAACTGACGGAAAAGGAGAGAGACCTGAAGAATAAGTAGTGAAAGCATCAATCAAGACATAAGAACAAAACATTAGCATTTCTCTGCCG
TGGAGAATTGCTTATCAACCACCAGAGGAGGCTTCTTTCTTGAACAATAAACATTTCTTATAAGGATTCACAGATTCACATACGACTGAT
CTTGATTTTTGGAAATGAATGAGGTTTCTTTTTTCTTTTTCCTTTTTTTAATTTTGGGGTAAGTTATGATATTTGGATGGATTTTTAAAT
TCTTTCCTGATAACATATTTAGCACATGTTCTAAATTATAATCCTATAGCAAACAGTTGGAGCATTATTCAAACTGAAAGTGGAAAAATT
TAAATTTCCAATTTATTCTAGATTTCCTCAGAGCATAATTATTCTGTTAAATCCTCAATGAGTGTGATGTAAACCACCTCTATCCAGAAA
TATACATTCTTTTCTCATCATGTTGGACACAGTTGAGGGTGACATGCACAGAACTGGAACAGATCACTATTAGTGGAAAATACCAAATGG
ACAAATAAATACCAGTCGTTTTCTCCGTTCTCCAAGCACAGGAGCCAGGTTTACCATCTGAACAATGAAGACGAAGGGAGTAAATAAAGG
AAGAATTCTCATCTTTTTTCCTGATCATTCAAAGAACAGTTTCTCAAGGTTAAGCCAAGTCCTCCTTGCAAGTTGCCAAATAATAGCTTA
GGAAAAGAATTAGTCTGCCTGCATGATGATCTTCTTAGGCAAAAACGTCTTCACAGCCCTTGACCTTGGTGAATTTTTTTCCCCAAAAGC
ATCCAAAAGAAGAATTATAAACCCCAGAATGAGATGGAAATAAACAAGTATTTTTTTTTATGATGTTTGGCCTGAACTGTGGGCTTTAAT
TGGGGGATACTGATCGTTTGGAAAGAAGTGAGAAAATTCTGAAGAAATGGCGGCCTTGGGCTAGGCGGGGTCCCCTATTTCTTCTGTTTC
TCACTGAAGTCCTACTGCTGAGCCAAGACTCAGTCACTCTGGAAAGAGCATGACCGATAAAGAAAACAGTTCCTTTCTGATGGGGAGCGT
CTGAGTGCAGATCATGAGGCTCTTTCTCTAGGTTTAATTCTTTTCCATGGTGACCGGACTTGGTGTCTTGTAGCCTGGTTACGAAGTGGG
ACGTTGAGCTTCTACTGACGATGCCCTGCATGGACCAGCTGGGATCTGGCTGGGGCTGCCCTGTGTCCCTAACGACCATAGGCAATCCAT
CTTCTTGTGTCAGCAATTTCTGGACACCCACTGTTTTCCACCAAGAGCTGAGGTGGCAACAACTCAGTGAGCAATAAACAAAATGACACA
GAAATGCACAGTGTTGTTATGAAGGAGCCTGTTTACCTGTGTTCAAAATCTGGCACCATTCCCTTGAGCAGGGCCCGCTCAGGAGGGACC
AGGTCTGCCAGTTTCTGTGCCTGCAGAGAGACGAAGCCCCACGAGCCACACCCTACTCTACAAGAGGAAAGGGGGTTGGATGGGAAGAAT
CTATTTTGCTGTTTTGGAAAGCACACAGCCGACCTACAAACCTCCTGTGATGGTGTTTCTTCGGATGTGTAAAATAAGGCTTTATTTGTC

>97822_97822_6_UVRAG-ZMAT4_UVRAG_chr11_75728024_ENST00000539288_ZMAT4_chr8_40389757_ENST00000315769_length(amino acids)=151AA_BP=
MCHFVYCSLSCCHLSSWWKTVGVQKLLTQEDGLPMVVRDTGQPQPDPSWSMQGIVSRSSTSHFVTRLQDTKSGHHGKELNLEKEPHDLHS

--------------------------------------------------------------

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Fusion Gene PPI Analysis for UVRAG-ZMAT4


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for UVRAG-ZMAT4


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for UVRAG-ZMAT4


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource