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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:VPS13A-DHX29 (FusionGDB2 ID:98251) |
Fusion Gene Summary for VPS13A-DHX29 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: VPS13A-DHX29 | Fusion gene ID: 98251 | Hgene | Tgene | Gene symbol | VPS13A | DHX29 | Gene ID | 23230 | 54505 |
| Gene name | vacuolar protein sorting 13 homolog A | DExH-box helicase 29 | |
| Synonyms | CHAC|CHOREIN | DDX29 | |
| Cytomap | 9q21.2 | 5q11.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | vacuolar protein sorting-associated protein 13Achorea-acanthocytosis proteinvacuolar protein sorting 13A | ATP-dependent RNA helicase DHX29DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 29DEAH (Asp-Glu-Ala-His) box polypeptide 29DEAH box protein 29DEAH-box helicase 29nucleic acid helicase DDXx | |
| Modification date | 20200313 | 20200320 | |
| UniProtAcc | . | Q7Z478 | |
| Ensembl transtripts involved in fusion gene | ENST00000357409, ENST00000360280, ENST00000376634, ENST00000376636, ENST00000376646, ENST00000423463, ENST00000484581, | ENST00000251636, | |
| Fusion gene scores | * DoF score | 8 X 5 X 7=280 | 9 X 7 X 9=567 |
| # samples | 8 | 12 | |
| ** MAII score | log2(8/280*10)=-1.8073549220576 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(12/567*10)=-2.24031432933371 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: VPS13A [Title/Abstract] AND DHX29 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | VPS13A(79875140)-DHX29(54573110), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene breakpoints across VPS13A (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across DHX29 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | KIRC | TCGA-B0-4819-01A | VPS13A | chr9 | 79875140 | + | DHX29 | chr5 | 54573110 | - |
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Fusion Gene ORF analysis for VPS13A-DHX29 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000357409 | ENST00000251636 | VPS13A | chr9 | 79875140 | + | DHX29 | chr5 | 54573110 | - |
| In-frame | ENST00000360280 | ENST00000251636 | VPS13A | chr9 | 79875140 | + | DHX29 | chr5 | 54573110 | - |
| In-frame | ENST00000376634 | ENST00000251636 | VPS13A | chr9 | 79875140 | + | DHX29 | chr5 | 54573110 | - |
| In-frame | ENST00000376636 | ENST00000251636 | VPS13A | chr9 | 79875140 | + | DHX29 | chr5 | 54573110 | - |
| intron-3CDS | ENST00000376646 | ENST00000251636 | VPS13A | chr9 | 79875140 | + | DHX29 | chr5 | 54573110 | - |
| intron-3CDS | ENST00000423463 | ENST00000251636 | VPS13A | chr9 | 79875140 | + | DHX29 | chr5 | 54573110 | - |
| intron-3CDS | ENST00000484581 | ENST00000251636 | VPS13A | chr9 | 79875140 | + | DHX29 | chr5 | 54573110 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000376634 | VPS13A | chr9 | 79875140 | + | ENST00000251636 | DHX29 | chr5 | 54573110 | - | 5023 | 2779 | 325 | 4779 | 1484 |
| ENST00000376636 | VPS13A | chr9 | 79875140 | + | ENST00000251636 | DHX29 | chr5 | 54573110 | - | 4931 | 2687 | 233 | 4687 | 1484 |
| ENST00000360280 | VPS13A | chr9 | 79875140 | + | ENST00000251636 | DHX29 | chr5 | 54573110 | - | 4931 | 2687 | 233 | 4687 | 1484 |
| ENST00000357409 | VPS13A | chr9 | 79875140 | + | ENST00000251636 | DHX29 | chr5 | 54573110 | - | 4842 | 2598 | 144 | 4598 | 1484 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000376634 | ENST00000251636 | VPS13A | chr9 | 79875140 | + | DHX29 | chr5 | 54573110 | - | 0.000355517 | 0.9996445 |
| ENST00000376636 | ENST00000251636 | VPS13A | chr9 | 79875140 | + | DHX29 | chr5 | 54573110 | - | 0.000316502 | 0.9996835 |
| ENST00000360280 | ENST00000251636 | VPS13A | chr9 | 79875140 | + | DHX29 | chr5 | 54573110 | - | 0.000316502 | 0.9996835 |
| ENST00000357409 | ENST00000251636 | VPS13A | chr9 | 79875140 | + | DHX29 | chr5 | 54573110 | - | 0.000287691 | 0.9997123 |
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Fusion Genomic Features for VPS13A-DHX29 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for VPS13A-DHX29 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr9:79875140/chr5:54573110) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | DHX29 |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity. {ECO:0000255|HAMAP-Rule:MF_03068, ECO:0000269|PubMed:19109895, ECO:0000269|PubMed:23706745}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | VPS13A | chr9:79875140 | chr5:54573110 | ENST00000357409 | + | 23 | 69 | 212_245 | 809 | 3096.0 | Repeat | Note=TPR 1 |
| Hgene | VPS13A | chr9:79875140 | chr5:54573110 | ENST00000357409 | + | 23 | 69 | 373_406 | 809 | 3096.0 | Repeat | Note=TPR 2 |
| Hgene | VPS13A | chr9:79875140 | chr5:54573110 | ENST00000357409 | + | 23 | 69 | 537_575 | 809 | 3096.0 | Repeat | Note=TPR 3 |
| Hgene | VPS13A | chr9:79875140 | chr5:54573110 | ENST00000360280 | + | 23 | 72 | 212_245 | 809 | 3175.0 | Repeat | Note=TPR 1 |
| Hgene | VPS13A | chr9:79875140 | chr5:54573110 | ENST00000360280 | + | 23 | 72 | 373_406 | 809 | 3175.0 | Repeat | Note=TPR 2 |
| Hgene | VPS13A | chr9:79875140 | chr5:54573110 | ENST00000360280 | + | 23 | 72 | 537_575 | 809 | 3175.0 | Repeat | Note=TPR 3 |
| Hgene | VPS13A | chr9:79875140 | chr5:54573110 | ENST00000376634 | + | 23 | 69 | 212_245 | 809 | 3070.0 | Repeat | Note=TPR 1 |
| Hgene | VPS13A | chr9:79875140 | chr5:54573110 | ENST00000376634 | + | 23 | 69 | 373_406 | 809 | 3070.0 | Repeat | Note=TPR 2 |
| Hgene | VPS13A | chr9:79875140 | chr5:54573110 | ENST00000376634 | + | 23 | 69 | 537_575 | 809 | 3070.0 | Repeat | Note=TPR 3 |
| Hgene | VPS13A | chr9:79875140 | chr5:54573110 | ENST00000376636 | + | 23 | 71 | 212_245 | 809 | 3136.0 | Repeat | Note=TPR 1 |
| Hgene | VPS13A | chr9:79875140 | chr5:54573110 | ENST00000376636 | + | 23 | 71 | 373_406 | 809 | 3136.0 | Repeat | Note=TPR 2 |
| Hgene | VPS13A | chr9:79875140 | chr5:54573110 | ENST00000376636 | + | 23 | 71 | 537_575 | 809 | 3136.0 | Repeat | Note=TPR 3 |
| Tgene | DHX29 | chr9:79875140 | chr5:54573110 | ENST00000251636 | 11 | 27 | 789_793 | 703 | 1370.0 | Compositional bias | Note=Poly-Glu | |
| Tgene | DHX29 | chr9:79875140 | chr5:54573110 | ENST00000251636 | 11 | 27 | 849_1026 | 703 | 1370.0 | Domain | Helicase C-terminal | |
| Tgene | DHX29 | chr9:79875140 | chr5:54573110 | ENST00000251636 | 11 | 27 | 702_705 | 703 | 1370.0 | Motif | DEAH box |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | VPS13A | chr9:79875140 | chr5:54573110 | ENST00000357409 | + | 23 | 69 | 842_848 | 809 | 3096.0 | Motif | FFAT |
| Hgene | VPS13A | chr9:79875140 | chr5:54573110 | ENST00000360280 | + | 23 | 72 | 842_848 | 809 | 3175.0 | Motif | FFAT |
| Hgene | VPS13A | chr9:79875140 | chr5:54573110 | ENST00000376634 | + | 23 | 69 | 842_848 | 809 | 3070.0 | Motif | FFAT |
| Hgene | VPS13A | chr9:79875140 | chr5:54573110 | ENST00000376636 | + | 23 | 71 | 842_848 | 809 | 3136.0 | Motif | FFAT |
| Hgene | VPS13A | chr9:79875140 | chr5:54573110 | ENST00000357409 | + | 23 | 69 | 2615_3174 | 809 | 3096.0 | Region | Required for mitochondrial localization |
| Hgene | VPS13A | chr9:79875140 | chr5:54573110 | ENST00000360280 | + | 23 | 72 | 2615_3174 | 809 | 3175.0 | Region | Required for mitochondrial localization |
| Hgene | VPS13A | chr9:79875140 | chr5:54573110 | ENST00000376634 | + | 23 | 69 | 2615_3174 | 809 | 3070.0 | Region | Required for mitochondrial localization |
| Hgene | VPS13A | chr9:79875140 | chr5:54573110 | ENST00000376636 | + | 23 | 71 | 2615_3174 | 809 | 3136.0 | Region | Required for mitochondrial localization |
| Hgene | VPS13A | chr9:79875140 | chr5:54573110 | ENST00000357409 | + | 23 | 69 | 1256_1289 | 809 | 3096.0 | Repeat | Note=TPR 4 |
| Hgene | VPS13A | chr9:79875140 | chr5:54573110 | ENST00000357409 | + | 23 | 69 | 1291_1320 | 809 | 3096.0 | Repeat | Note=TPR 5 |
| Hgene | VPS13A | chr9:79875140 | chr5:54573110 | ENST00000357409 | + | 23 | 69 | 2009_2041 | 809 | 3096.0 | Repeat | Note=TPR 6 |
| Hgene | VPS13A | chr9:79875140 | chr5:54573110 | ENST00000357409 | + | 23 | 69 | 2568_2601 | 809 | 3096.0 | Repeat | Note=TPR 7 |
| Hgene | VPS13A | chr9:79875140 | chr5:54573110 | ENST00000357409 | + | 23 | 69 | 2717_2751 | 809 | 3096.0 | Repeat | Note=TPR 8 |
| Hgene | VPS13A | chr9:79875140 | chr5:54573110 | ENST00000357409 | + | 23 | 69 | 2860_2898 | 809 | 3096.0 | Repeat | Note=TPR 9 |
| Hgene | VPS13A | chr9:79875140 | chr5:54573110 | ENST00000357409 | + | 23 | 69 | 3086_3119 | 809 | 3096.0 | Repeat | Note=TPR 10 |
| Hgene | VPS13A | chr9:79875140 | chr5:54573110 | ENST00000360280 | + | 23 | 72 | 1256_1289 | 809 | 3175.0 | Repeat | Note=TPR 4 |
| Hgene | VPS13A | chr9:79875140 | chr5:54573110 | ENST00000360280 | + | 23 | 72 | 1291_1320 | 809 | 3175.0 | Repeat | Note=TPR 5 |
| Hgene | VPS13A | chr9:79875140 | chr5:54573110 | ENST00000360280 | + | 23 | 72 | 2009_2041 | 809 | 3175.0 | Repeat | Note=TPR 6 |
| Hgene | VPS13A | chr9:79875140 | chr5:54573110 | ENST00000360280 | + | 23 | 72 | 2568_2601 | 809 | 3175.0 | Repeat | Note=TPR 7 |
| Hgene | VPS13A | chr9:79875140 | chr5:54573110 | ENST00000360280 | + | 23 | 72 | 2717_2751 | 809 | 3175.0 | Repeat | Note=TPR 8 |
| Hgene | VPS13A | chr9:79875140 | chr5:54573110 | ENST00000360280 | + | 23 | 72 | 2860_2898 | 809 | 3175.0 | Repeat | Note=TPR 9 |
| Hgene | VPS13A | chr9:79875140 | chr5:54573110 | ENST00000360280 | + | 23 | 72 | 3086_3119 | 809 | 3175.0 | Repeat | Note=TPR 10 |
| Hgene | VPS13A | chr9:79875140 | chr5:54573110 | ENST00000376634 | + | 23 | 69 | 1256_1289 | 809 | 3070.0 | Repeat | Note=TPR 4 |
| Hgene | VPS13A | chr9:79875140 | chr5:54573110 | ENST00000376634 | + | 23 | 69 | 1291_1320 | 809 | 3070.0 | Repeat | Note=TPR 5 |
| Hgene | VPS13A | chr9:79875140 | chr5:54573110 | ENST00000376634 | + | 23 | 69 | 2009_2041 | 809 | 3070.0 | Repeat | Note=TPR 6 |
| Hgene | VPS13A | chr9:79875140 | chr5:54573110 | ENST00000376634 | + | 23 | 69 | 2568_2601 | 809 | 3070.0 | Repeat | Note=TPR 7 |
| Hgene | VPS13A | chr9:79875140 | chr5:54573110 | ENST00000376634 | + | 23 | 69 | 2717_2751 | 809 | 3070.0 | Repeat | Note=TPR 8 |
| Hgene | VPS13A | chr9:79875140 | chr5:54573110 | ENST00000376634 | + | 23 | 69 | 2860_2898 | 809 | 3070.0 | Repeat | Note=TPR 9 |
| Hgene | VPS13A | chr9:79875140 | chr5:54573110 | ENST00000376634 | + | 23 | 69 | 3086_3119 | 809 | 3070.0 | Repeat | Note=TPR 10 |
| Hgene | VPS13A | chr9:79875140 | chr5:54573110 | ENST00000376636 | + | 23 | 71 | 1256_1289 | 809 | 3136.0 | Repeat | Note=TPR 4 |
| Hgene | VPS13A | chr9:79875140 | chr5:54573110 | ENST00000376636 | + | 23 | 71 | 1291_1320 | 809 | 3136.0 | Repeat | Note=TPR 5 |
| Hgene | VPS13A | chr9:79875140 | chr5:54573110 | ENST00000376636 | + | 23 | 71 | 2009_2041 | 809 | 3136.0 | Repeat | Note=TPR 6 |
| Hgene | VPS13A | chr9:79875140 | chr5:54573110 | ENST00000376636 | + | 23 | 71 | 2568_2601 | 809 | 3136.0 | Repeat | Note=TPR 7 |
| Hgene | VPS13A | chr9:79875140 | chr5:54573110 | ENST00000376636 | + | 23 | 71 | 2717_2751 | 809 | 3136.0 | Repeat | Note=TPR 8 |
| Hgene | VPS13A | chr9:79875140 | chr5:54573110 | ENST00000376636 | + | 23 | 71 | 2860_2898 | 809 | 3136.0 | Repeat | Note=TPR 9 |
| Hgene | VPS13A | chr9:79875140 | chr5:54573110 | ENST00000376636 | + | 23 | 71 | 3086_3119 | 809 | 3136.0 | Repeat | Note=TPR 10 |
| Tgene | DHX29 | chr9:79875140 | chr5:54573110 | ENST00000251636 | 11 | 27 | 222_256 | 703 | 1370.0 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | DHX29 | chr9:79875140 | chr5:54573110 | ENST00000251636 | 11 | 27 | 283_310 | 703 | 1370.0 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | DHX29 | chr9:79875140 | chr5:54573110 | ENST00000251636 | 11 | 27 | 492_519 | 703 | 1370.0 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | DHX29 | chr9:79875140 | chr5:54573110 | ENST00000251636 | 11 | 27 | 10_53 | 703 | 1370.0 | Compositional bias | Note=Ala-rich | |
| Tgene | DHX29 | chr9:79875140 | chr5:54573110 | ENST00000251636 | 11 | 27 | 582_755 | 703 | 1370.0 | Domain | Helicase ATP-binding | |
| Tgene | DHX29 | chr9:79875140 | chr5:54573110 | ENST00000251636 | 11 | 27 | 595_602 | 703 | 1370.0 | Nucleotide binding | ATP |
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Fusion Gene Sequence for VPS13A-DHX29 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >98251_98251_1_VPS13A-DHX29_VPS13A_chr9_79875140_ENST00000357409_DHX29_chr5_54573110_ENST00000251636_length(transcript)=4842nt_BP=2598nt GCCTCCGTCTCTCGCTGGGCTCGCTAGGGCTGCGCGTTGGGCCAGCGGGGGCGCCGCAGCTGAAGCCGCCCCGGAGCCGGTGAACCGAAT TACCTCGAGGGAGGGGCGTGGGGAAGGCGGCGGGAGGAGGAGCGCACGGGCCGGCTGCCGTGCCCACCACGGCTGAGGAACATGGTTTTC GAGTCGGTGGTCGTGGACGTGTTGAACCGGTTCTTGGGGGACTATGTGGTGGACTTGGACACGTCCCAGCTCTCTCTGGGCATCTGGAAA GGAGCTGTGGCCCTCAAGAATCTTCAAATTAAAGAAAATGCCCTGAGTCAACTGGATGTACCATTTAAAGTTAAAGTTGGTCACATAGGT AATCTTAAACTTATAATTCCATGGAAAAACCTTTATACTCAACCTGTTGAAGCCGTATTGGAAGAAATTTATTTACTTATAGTGCCTTCT TCTAGAATAAAATATGATCCTTTAAAAGAAGAGAAACAACTCATGGAAGCAAAGCAACAGGAACTGAAAAGAATAGAAGAAGCAAAACAA AAAGTAGTTGATCAAGAACAACATCTGCCGGAAAAACAGGACACTTTTGCAGAAAAATTAGTTACACAGATCATAAAAAATCTTCAGGTG AAAATTTCCAGTATCCATATTCGTTATGAAGATGATATCACAAATCGGGACAAACCGCTGTCATTTGGTATTTCCCTTCAAAATCTGAGC ATGCAGACAACTGATCAATACTGGGTTCCATGTTTACATGATGAAACTGAGAAACTGGTTCGTAAGTTAATCCGATTGGATAACCTGTTT GCCTATTGGAATGTGAAGTCTCAGATGTTTTATCTTAGTGATTATGATAACTCCTTGGACGACTTGAAGAATGGCATTGTCAATGAAAAT ATTGTTCCAGAAGGTTATGATTTTGTATTTCGTCCCATATCTGCTAATGCCAAACTTGTGATGAATCGCCGATCTGATTTTGACTTTTCT GCCCCCAAAATAAACTTGGAAATTGAGTTACATAACATAGCAATTGAATTTAATAAACCACAGTATTTCAGTATTATGGAGCTTCTTGAA TCAGTTGATATGATGGCACAAAATCTGCCATATAGGAAGTTCAAACCTGATGTGCCTCTTCACCACCATGCCAGAGAATGGTGGGCTTAT GCTATACATGGCGTTCTTGAAGTAAATGTTTGCCCCAGGTTATGGATGTGGTCATGGAAGCATATTAGAAAACATAGGCAAAAAGTGAAG CAATATAAAGAACTGTATAAAAAAAAGTTAACAAGTAAGAAGCCACCTGGTGAACTTCTCGTGTCTTTGGAGGAGTTGGAAAAAACCTTG GATGTCTTTAATATAACTATAGCTAGACAGACGGCAGAAGTTGAGGTAAAGAAAGCTGGATACAAAATTTACAAAGAAGGAGTAAAAGAT CCAGAGGATAATAAAGGGTGGTTTAGCTGGCTATGGTCTTGGTCAGAACAAAATACTAATGAACAGCAACCAGATGTTCAACCTGAAACT CTTGAAGAAATGTTGACACCTGAAGAAAAAGCTTTACTCTATGAAGCAATTGGCTATAGTGAAACAGCAGTTGATCCAACTTTACTAAAA ACATTTGAAGCCTTGAAGTTTTTTGTCCACTTGAAAAGTATGTCTATTGTTCTAAGAGAAAATCATCAAAAACCTGAGCTGGTAGATATT GTAATAGAAGAATTTAGCACCTTAATTGTGCAAAGACCAGGAGCACAAGCAATAAAATTTGAAACTAAAATAGATTCATTTCATATTACT GGCTTACCAGATAATTCAGAAAAACCCCGCCTCCTGTCTTCATTGGATGATGCAATGTCACTTTTCCAAATTACATTTGAGATAAATCCA TTAGATGAAACTGTTTCTCAGAGGTGTATCATAGAAGCTGAACCTTTAGAAATCATATATGATGCAAGGACAGTGAATAGTATAGTGGAA TTCTTCAGACCTCCAAAAGAGGTACATCTAGCACAGCTCACTGCAGCAACTTTGACAAAACTGGAAGAATTTCGCAGTAAGACAGCAACA GGTCTACTGTATATTATTGAAACACAGAAAGTTCTTGATCTCAAAATTAATTTGAAGGCTTCATATATTATTGTCCCACAAGATGGAATT TTTAGTCCTACATCAAATCTGCTTCTTTTGGACCTTGGTCATCTAAAGGTGACGAGTAAAAGTCGTTCTGAATTACCAGATGTGAAACAA GGTGAGGCCAATCTTAAAGAGATAATGGATAGAGCTTATGATTCATTTGATATTCAACTTACAAGTGTACAGCTGCTTTACAGTAGAGTT GGTGATAATTGGAGAGAAGCACGAAAACTCAGTGTATCTACCCAGCATATTTTGGTACCCATGCACTTCAATTTGGAACTGTCTAAGGCC ATGGTTTTCATGGATGTAAGGATGCCCAAATTCAAGATTTATGGAAAGTTACCTCTTATTTCTTTACGAATCTCAGATAAAAAACTACAA GGGATTATGGAATTGATTGAAAGCATTCCAAAACCTGAACCAGTAACTGAAGTATCTGCCCCTGTCAAATCATTCCAGGTTCATGAAAGA AGTGTCCAGTCAGACTTCCTACTAATTATCTTGAAGGAAATTTTACAGAAACGTTCTGATCTACACTTGATTCTAATGAGTGCCACTGTG GACAGCGAAAAATTTTCTACATATTTCACACACTGCCCCATTCTCAGAATTTCAGGAAGAAGTTATCCTGTTGAGGTTTTTCATCTTGAA GATATAATAGAAGAAACAGGCTTTGTACTGGAAAAAGACTCAGAATATTGTCAGAAATTTCTGGAAGAGGAAGAAGAAGTAACCATTAAT GTTACAAGCAAAGCAGGGGGAATAAAAAAATATCAGGAATACATCCCAGTTCAGACTGGAGCACATGCTGATTTAAATCCATTTTACCAA AAGTACAGCAGCCGCACTCAGCATGCTATTCTATACATGAATCCTCATAAAATCAACCTGGATCTCATTTTGGAACTTCTTGCATACTTA GATAAAAGTCCCCAATTCAGAAATATTGAAGGAGCAGTATTGATCTTTTTACCAGGACTTGCTCATATTCAGCAGTTGTATGATCTTCTA TCAAATGATAGAAGATTTTATTCTGAACGATATAAAGTGATAGCTCTGCATTCTATTCTTTCAACCCAAGATCAAGCTGCAGCATTCACA CTTCCCCCTCCAGGAGTCAGGAAGATTGTTTTAGCAACCAATATTGCAGAGACGGGTATCACTATTCCTGATGTTGTATTTGTAATTGAT ACTGGAAGAACAAAAGAAAATAAGTACCATGAAAGCAGTCAGATGAGTTCTTTGGTGGAGACGTTTGTCAGTAAAGCCAGTGCTTTGCAG CGCCAGGGAAGAGCTGGGCGGGTCAGAGATGGCTTCTGTTTCCGAATGTACACAAGAGAAAGATTTGAAGGCTTTATGGATTATTCTGTT CCTGAAATCTTACGTGTACCTTTGGAGGAATTATGCCTTCATATTATGAAATGTAATCTTGGTTCTCCTGAAGATTTCCTCTCCAAAGCC TTAGATCCTCCTCAGCTCCAAGTGATCAGCAATGCAATGAATTTGCTCCGAAAAATTGGAGCTTGTGAATTAAATGAGCCTAAACTGACT CCGTTGGGCCAACACCTTGCAGCTTTACCTGTGAATGTCAAGATTGGCAAGATGCTTATTTTTGGTGCCATATTTGGCTGCCTTGACCCA GTGGCAACACTAGCTGCAGTTATGACAGAGAAGTCTCCTTTTACCACACCAATTGGTCGAAAAGATGAAGCAGATCTTGCAAAATCAGCT TTGGCCATGGCGGATTCAGACCACCTGACGATCTACAATGCATATCTAGGATGGAAGAAAGCACGACAAGAAGGAGGTTATCGTTCTGAA ATCACATACTGCCGGAGGAACTTTCTTAATAGAACATCACTGTTAACCCTAGAGGATGTAAAGCAGGAGTTAATAAAGTTGGTTAAGGCA GCAGGATTTTCATCTTCCACAACTTCTACCAGCTGGGAAGGAAACAGAGCCTCACAGACCCTCTCATTCCAAGAAATTGCCCTTCTTAAA GCTGTACTGGTGGCTGGACTGTATGACAATGTGGGGAAGATAATCTATACAAAGTCAGTGGATGTTACAGAAAAATTGGCTTGCATTGTG GAGACGGCCCAAGGCAAAGCACAAGTACACCCATCCTCAGTAAATCGAGATTTGCAAACTCATGGATGGCTCTTATACCAGGAGAAGATA AGGTATGCCAGAGTGTATTTGAGAGAAACTACCCTAATAACCCCTTTTCCAGTTTTACTTTTTGGTGGTGATATAGAAGTTCAGCACCGA GAACGTCTTCTTTCTATTGATGGCTGGATCTATTTTCAGGCCCCTGTAAAGATAGCTGTCATTTTCAAGCAGCTGAGAGTTCTCATTGAT TCAGTTTTAAGAAAAAAGCTTGAAAATCCAAAGATGTCCCTTGAAAATGACAAGATTCTGCAGATCATTACGGAATTGATAAAAACAGAG AATAACTGAAACTGAAATTCATGGTCAACTGCTTTAAAAATTAAGATGAAGATACAGTCATGAAATTATCTGAAAATGGGTCATCACATT AAGTATTTCATTACTTAAAATGTTGGTACTAGCCATTAACTTAAAGGTGGTGGGAAAAAAGCACATACTTTAAACATGTATAATTTTCTA >98251_98251_1_VPS13A-DHX29_VPS13A_chr9_79875140_ENST00000357409_DHX29_chr5_54573110_ENST00000251636_length(amino acids)=1484AA_BP=818 MPCPPRLRNMVFESVVVDVLNRFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENALSQLDVPFKVKVGHIGNLKLIIPWKNLYTQPVEA VLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIEEAKQKVVDQEQHLPEKQDTFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDK PLSFGISLQNLSMQTTDQYWVPCLHDETEKLVRKLIRLDNLFAYWNVKSQMFYLSDYDNSLDDLKNGIVNENIVPEGYDFVFRPISANAK LVMNRRSDFDFSAPKINLEIELHNIAIEFNKPQYFSIMELLESVDMMAQNLPYRKFKPDVPLHHHAREWWAYAIHGVLEVNVCPRLWMWS WKHIRKHRQKVKQYKELYKKKLTSKKPPGELLVSLEELEKTLDVFNITIARQTAEVEVKKAGYKIYKEGVKDPEDNKGWFSWLWSWSEQN TNEQQPDVQPETLEEMLTPEEKALLYEAIGYSETAVDPTLLKTFEALKFFVHLKSMSIVLRENHQKPELVDIVIEEFSTLIVQRPGAQAI KFETKIDSFHITGLPDNSEKPRLLSSLDDAMSLFQITFEINPLDETVSQRCIIEAEPLEIIYDARTVNSIVEFFRPPKEVHLAQLTAATL TKLEEFRSKTATGLLYIIETQKVLDLKINLKASYIIVPQDGIFSPTSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRAYDSFDI QLTSVQLLYSRVGDNWREARKLSVSTQHILVPMHFNLELSKAMVFMDVRMPKFKIYGKLPLISLRISDKKLQGIMELIESIPKPEPVTEV SAPVKSFQVHERSVQSDFLLIILKEILQKRSDLHLILMSATVDSEKFSTYFTHCPILRISGRSYPVEVFHLEDIIEETGFVLEKDSEYCQ KFLEEEEEVTINVTSKAGGIKKYQEYIPVQTGAHADLNPFYQKYSSRTQHAILYMNPHKINLDLILELLAYLDKSPQFRNIEGAVLIFLP GLAHIQQLYDLLSNDRRFYSERYKVIALHSILSTQDQAAAFTLPPPGVRKIVLATNIAETGITIPDVVFVIDTGRTKENKYHESSQMSSL VETFVSKASALQRQGRAGRVRDGFCFRMYTRERFEGFMDYSVPEILRVPLEELCLHIMKCNLGSPEDFLSKALDPPQLQVISNAMNLLRK IGACELNEPKLTPLGQHLAALPVNVKIGKMLIFGAIFGCLDPVATLAAVMTEKSPFTTPIGRKDEADLAKSALAMADSDHLTIYNAYLGW KKARQEGGYRSEITYCRRNFLNRTSLLTLEDVKQELIKLVKAAGFSSSTTSTSWEGNRASQTLSFQEIALLKAVLVAGLYDNVGKIIYTK SVDVTEKLACIVETAQGKAQVHPSSVNRDLQTHGWLLYQEKIRYARVYLRETTLITPFPVLLFGGDIEVQHRERLLSIDGWIYFQAPVKI -------------------------------------------------------------- >98251_98251_2_VPS13A-DHX29_VPS13A_chr9_79875140_ENST00000360280_DHX29_chr5_54573110_ENST00000251636_length(transcript)=4931nt_BP=2687nt TTCCTCCCTCTCAGGGCTGCGCGCCCAGGTCTGCGCCGCGCTCCGCCTCCAGCCGCGCGCAGACTTGCGCACGCGTCGTGAGAGCGACCG CCTCCGTCTCTCGCTGGGCTCGCTAGGGCTGCGCGTTGGGCCAGCGGGGGCGCCGCAGCTGAAGCCGCCCCGGAGCCGGTGAACCGAATT ACCTCGAGGGAGGGGCGTGGGGAAGGCGGCGGGAGGAGGAGCGCACGGGCCGGCTGCCGTGCCCACCACGGCTGAGGAACATGGTTTTCG AGTCGGTGGTCGTGGACGTGTTGAACCGGTTCTTGGGGGACTATGTGGTGGACTTGGACACGTCCCAGCTCTCTCTGGGCATCTGGAAAG GAGCTGTGGCCCTCAAGAATCTTCAAATTAAAGAAAATGCCCTGAGTCAACTGGATGTACCATTTAAAGTTAAAGTTGGTCACATAGGTA ATCTTAAACTTATAATTCCATGGAAAAACCTTTATACTCAACCTGTTGAAGCCGTATTGGAAGAAATTTATTTACTTATAGTGCCTTCTT CTAGAATAAAATATGATCCTTTAAAAGAAGAGAAACAACTCATGGAAGCAAAGCAACAGGAACTGAAAAGAATAGAAGAAGCAAAACAAA AAGTAGTTGATCAAGAACAACATCTGCCGGAAAAACAGGACACTTTTGCAGAAAAATTAGTTACACAGATCATAAAAAATCTTCAGGTGA AAATTTCCAGTATCCATATTCGTTATGAAGATGATATCACAAATCGGGACAAACCGCTGTCATTTGGTATTTCCCTTCAAAATCTGAGCA TGCAGACAACTGATCAATACTGGGTTCCATGTTTACATGATGAAACTGAGAAACTGGTTCGTAAGTTAATCCGATTGGATAACCTGTTTG CCTATTGGAATGTGAAGTCTCAGATGTTTTATCTTAGTGATTATGATAACTCCTTGGACGACTTGAAGAATGGCATTGTCAATGAAAATA TTGTTCCAGAAGGTTATGATTTTGTATTTCGTCCCATATCTGCTAATGCCAAACTTGTGATGAATCGCCGATCTGATTTTGACTTTTCTG CCCCCAAAATAAACTTGGAAATTGAGTTACATAACATAGCAATTGAATTTAATAAACCACAGTATTTCAGTATTATGGAGCTTCTTGAAT CAGTTGATATGATGGCACAAAATCTGCCATATAGGAAGTTCAAACCTGATGTGCCTCTTCACCACCATGCCAGAGAATGGTGGGCTTATG CTATACATGGCGTTCTTGAAGTAAATGTTTGCCCCAGGTTATGGATGTGGTCATGGAAGCATATTAGAAAACATAGGCAAAAAGTGAAGC AATATAAAGAACTGTATAAAAAAAAGTTAACAAGTAAGAAGCCACCTGGTGAACTTCTCGTGTCTTTGGAGGAGTTGGAAAAAACCTTGG ATGTCTTTAATATAACTATAGCTAGACAGACGGCAGAAGTTGAGGTAAAGAAAGCTGGATACAAAATTTACAAAGAAGGAGTAAAAGATC CAGAGGATAATAAAGGGTGGTTTAGCTGGCTATGGTCTTGGTCAGAACAAAATACTAATGAACAGCAACCAGATGTTCAACCTGAAACTC TTGAAGAAATGTTGACACCTGAAGAAAAAGCTTTACTCTATGAAGCAATTGGCTATAGTGAAACAGCAGTTGATCCAACTTTACTAAAAA CATTTGAAGCCTTGAAGTTTTTTGTCCACTTGAAAAGTATGTCTATTGTTCTAAGAGAAAATCATCAAAAACCTGAGCTGGTAGATATTG TAATAGAAGAATTTAGCACCTTAATTGTGCAAAGACCAGGAGCACAAGCAATAAAATTTGAAACTAAAATAGATTCATTTCATATTACTG GCTTACCAGATAATTCAGAAAAACCCCGCCTCCTGTCTTCATTGGATGATGCAATGTCACTTTTCCAAATTACATTTGAGATAAATCCAT TAGATGAAACTGTTTCTCAGAGGTGTATCATAGAAGCTGAACCTTTAGAAATCATATATGATGCAAGGACAGTGAATAGTATAGTGGAAT TCTTCAGACCTCCAAAAGAGGTACATCTAGCACAGCTCACTGCAGCAACTTTGACAAAACTGGAAGAATTTCGCAGTAAGACAGCAACAG GTCTACTGTATATTATTGAAACACAGAAAGTTCTTGATCTCAAAATTAATTTGAAGGCTTCATATATTATTGTCCCACAAGATGGAATTT TTAGTCCTACATCAAATCTGCTTCTTTTGGACCTTGGTCATCTAAAGGTGACGAGTAAAAGTCGTTCTGAATTACCAGATGTGAAACAAG GTGAGGCCAATCTTAAAGAGATAATGGATAGAGCTTATGATTCATTTGATATTCAACTTACAAGTGTACAGCTGCTTTACAGTAGAGTTG GTGATAATTGGAGAGAAGCACGAAAACTCAGTGTATCTACCCAGCATATTTTGGTACCCATGCACTTCAATTTGGAACTGTCTAAGGCCA TGGTTTTCATGGATGTAAGGATGCCCAAATTCAAGATTTATGGAAAGTTACCTCTTATTTCTTTACGAATCTCAGATAAAAAACTACAAG GGATTATGGAATTGATTGAAAGCATTCCAAAACCTGAACCAGTAACTGAAGTATCTGCCCCTGTCAAATCATTCCAGGTTCATGAAAGAA GTGTCCAGTCAGACTTCCTACTAATTATCTTGAAGGAAATTTTACAGAAACGTTCTGATCTACACTTGATTCTAATGAGTGCCACTGTGG ACAGCGAAAAATTTTCTACATATTTCACACACTGCCCCATTCTCAGAATTTCAGGAAGAAGTTATCCTGTTGAGGTTTTTCATCTTGAAG ATATAATAGAAGAAACAGGCTTTGTACTGGAAAAAGACTCAGAATATTGTCAGAAATTTCTGGAAGAGGAAGAAGAAGTAACCATTAATG TTACAAGCAAAGCAGGGGGAATAAAAAAATATCAGGAATACATCCCAGTTCAGACTGGAGCACATGCTGATTTAAATCCATTTTACCAAA AGTACAGCAGCCGCACTCAGCATGCTATTCTATACATGAATCCTCATAAAATCAACCTGGATCTCATTTTGGAACTTCTTGCATACTTAG ATAAAAGTCCCCAATTCAGAAATATTGAAGGAGCAGTATTGATCTTTTTACCAGGACTTGCTCATATTCAGCAGTTGTATGATCTTCTAT CAAATGATAGAAGATTTTATTCTGAACGATATAAAGTGATAGCTCTGCATTCTATTCTTTCAACCCAAGATCAAGCTGCAGCATTCACAC TTCCCCCTCCAGGAGTCAGGAAGATTGTTTTAGCAACCAATATTGCAGAGACGGGTATCACTATTCCTGATGTTGTATTTGTAATTGATA CTGGAAGAACAAAAGAAAATAAGTACCATGAAAGCAGTCAGATGAGTTCTTTGGTGGAGACGTTTGTCAGTAAAGCCAGTGCTTTGCAGC GCCAGGGAAGAGCTGGGCGGGTCAGAGATGGCTTCTGTTTCCGAATGTACACAAGAGAAAGATTTGAAGGCTTTATGGATTATTCTGTTC CTGAAATCTTACGTGTACCTTTGGAGGAATTATGCCTTCATATTATGAAATGTAATCTTGGTTCTCCTGAAGATTTCCTCTCCAAAGCCT TAGATCCTCCTCAGCTCCAAGTGATCAGCAATGCAATGAATTTGCTCCGAAAAATTGGAGCTTGTGAATTAAATGAGCCTAAACTGACTC CGTTGGGCCAACACCTTGCAGCTTTACCTGTGAATGTCAAGATTGGCAAGATGCTTATTTTTGGTGCCATATTTGGCTGCCTTGACCCAG TGGCAACACTAGCTGCAGTTATGACAGAGAAGTCTCCTTTTACCACACCAATTGGTCGAAAAGATGAAGCAGATCTTGCAAAATCAGCTT TGGCCATGGCGGATTCAGACCACCTGACGATCTACAATGCATATCTAGGATGGAAGAAAGCACGACAAGAAGGAGGTTATCGTTCTGAAA TCACATACTGCCGGAGGAACTTTCTTAATAGAACATCACTGTTAACCCTAGAGGATGTAAAGCAGGAGTTAATAAAGTTGGTTAAGGCAG CAGGATTTTCATCTTCCACAACTTCTACCAGCTGGGAAGGAAACAGAGCCTCACAGACCCTCTCATTCCAAGAAATTGCCCTTCTTAAAG CTGTACTGGTGGCTGGACTGTATGACAATGTGGGGAAGATAATCTATACAAAGTCAGTGGATGTTACAGAAAAATTGGCTTGCATTGTGG AGACGGCCCAAGGCAAAGCACAAGTACACCCATCCTCAGTAAATCGAGATTTGCAAACTCATGGATGGCTCTTATACCAGGAGAAGATAA GGTATGCCAGAGTGTATTTGAGAGAAACTACCCTAATAACCCCTTTTCCAGTTTTACTTTTTGGTGGTGATATAGAAGTTCAGCACCGAG AACGTCTTCTTTCTATTGATGGCTGGATCTATTTTCAGGCCCCTGTAAAGATAGCTGTCATTTTCAAGCAGCTGAGAGTTCTCATTGATT CAGTTTTAAGAAAAAAGCTTGAAAATCCAAAGATGTCCCTTGAAAATGACAAGATTCTGCAGATCATTACGGAATTGATAAAAACAGAGA ATAACTGAAACTGAAATTCATGGTCAACTGCTTTAAAAATTAAGATGAAGATACAGTCATGAAATTATCTGAAAATGGGTCATCACATTA AGTATTTCATTACTTAAAATGTTGGTACTAGCCATTAACTTAAAGGTGGTGGGAAAAAAGCACATACTTTAAACATGTATAATTTTCTAG >98251_98251_2_VPS13A-DHX29_VPS13A_chr9_79875140_ENST00000360280_DHX29_chr5_54573110_ENST00000251636_length(amino acids)=1484AA_BP=818 MPCPPRLRNMVFESVVVDVLNRFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENALSQLDVPFKVKVGHIGNLKLIIPWKNLYTQPVEA VLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIEEAKQKVVDQEQHLPEKQDTFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDK PLSFGISLQNLSMQTTDQYWVPCLHDETEKLVRKLIRLDNLFAYWNVKSQMFYLSDYDNSLDDLKNGIVNENIVPEGYDFVFRPISANAK LVMNRRSDFDFSAPKINLEIELHNIAIEFNKPQYFSIMELLESVDMMAQNLPYRKFKPDVPLHHHAREWWAYAIHGVLEVNVCPRLWMWS WKHIRKHRQKVKQYKELYKKKLTSKKPPGELLVSLEELEKTLDVFNITIARQTAEVEVKKAGYKIYKEGVKDPEDNKGWFSWLWSWSEQN TNEQQPDVQPETLEEMLTPEEKALLYEAIGYSETAVDPTLLKTFEALKFFVHLKSMSIVLRENHQKPELVDIVIEEFSTLIVQRPGAQAI KFETKIDSFHITGLPDNSEKPRLLSSLDDAMSLFQITFEINPLDETVSQRCIIEAEPLEIIYDARTVNSIVEFFRPPKEVHLAQLTAATL TKLEEFRSKTATGLLYIIETQKVLDLKINLKASYIIVPQDGIFSPTSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRAYDSFDI QLTSVQLLYSRVGDNWREARKLSVSTQHILVPMHFNLELSKAMVFMDVRMPKFKIYGKLPLISLRISDKKLQGIMELIESIPKPEPVTEV SAPVKSFQVHERSVQSDFLLIILKEILQKRSDLHLILMSATVDSEKFSTYFTHCPILRISGRSYPVEVFHLEDIIEETGFVLEKDSEYCQ KFLEEEEEVTINVTSKAGGIKKYQEYIPVQTGAHADLNPFYQKYSSRTQHAILYMNPHKINLDLILELLAYLDKSPQFRNIEGAVLIFLP GLAHIQQLYDLLSNDRRFYSERYKVIALHSILSTQDQAAAFTLPPPGVRKIVLATNIAETGITIPDVVFVIDTGRTKENKYHESSQMSSL VETFVSKASALQRQGRAGRVRDGFCFRMYTRERFEGFMDYSVPEILRVPLEELCLHIMKCNLGSPEDFLSKALDPPQLQVISNAMNLLRK IGACELNEPKLTPLGQHLAALPVNVKIGKMLIFGAIFGCLDPVATLAAVMTEKSPFTTPIGRKDEADLAKSALAMADSDHLTIYNAYLGW KKARQEGGYRSEITYCRRNFLNRTSLLTLEDVKQELIKLVKAAGFSSSTTSTSWEGNRASQTLSFQEIALLKAVLVAGLYDNVGKIIYTK SVDVTEKLACIVETAQGKAQVHPSSVNRDLQTHGWLLYQEKIRYARVYLRETTLITPFPVLLFGGDIEVQHRERLLSIDGWIYFQAPVKI -------------------------------------------------------------- >98251_98251_3_VPS13A-DHX29_VPS13A_chr9_79875140_ENST00000376634_DHX29_chr5_54573110_ENST00000251636_length(transcript)=5023nt_BP=2779nt AGGCGATGGGGAGGAGGCGGGGCCGACAGGAAAGAGGAGCCGGGCTCGGCGCGAAAAGGGCACCCTCCAGAGCCGCGGCCGCGCAGCCGC CTTTCCTCCCTCTCAGGGCTGCGCGCCCAGGTCTGCGCCGCGCTCCGCCTCCAGCCGCGCGCAGACTTGCGCACGCGTCGTGAGAGCGAC CGCCTCCGTCTCTCGCTGGGCTCGCTAGGGCTGCGCGTTGGGCCAGCGGGGGCGCCGCAGCTGAAGCCGCCCCGGAGCCGGTGAACCGAA TTACCTCGAGGGAGGGGCGTGGGGAAGGCGGCGGGAGGAGGAGCGCACGGGCCGGCTGCCGTGCCCACCACGGCTGAGGAACATGGTTTT CGAGTCGGTGGTCGTGGACGTGTTGAACCGGTTCTTGGGGGACTATGTGGTGGACTTGGACACGTCCCAGCTCTCTCTGGGCATCTGGAA AGGAGCTGTGGCCCTCAAGAATCTTCAAATTAAAGAAAATGCCCTGAGTCAACTGGATGTACCATTTAAAGTTAAAGTTGGTCACATAGG TAATCTTAAACTTATAATTCCATGGAAAAACCTTTATACTCAACCTGTTGAAGCCGTATTGGAAGAAATTTATTTACTTATAGTGCCTTC TTCTAGAATAAAATATGATCCTTTAAAAGAAGAGAAACAACTCATGGAAGCAAAGCAACAGGAACTGAAAAGAATAGAAGAAGCAAAACA AAAAGTAGTTGATCAAGAACAACATCTGCCGGAAAAACAGGACACTTTTGCAGAAAAATTAGTTACACAGATCATAAAAAATCTTCAGGT GAAAATTTCCAGTATCCATATTCGTTATGAAGATGATATCACAAATCGGGACAAACCGCTGTCATTTGGTATTTCCCTTCAAAATCTGAG CATGCAGACAACTGATCAATACTGGGTTCCATGTTTACATGATGAAACTGAGAAACTGGTTCGTAAGTTAATCCGATTGGATAACCTGTT TGCCTATTGGAATGTGAAGTCTCAGATGTTTTATCTTAGTGATTATGATAACTCCTTGGACGACTTGAAGAATGGCATTGTCAATGAAAA TATTGTTCCAGAAGGTTATGATTTTGTATTTCGTCCCATATCTGCTAATGCCAAACTTGTGATGAATCGCCGATCTGATTTTGACTTTTC TGCCCCCAAAATAAACTTGGAAATTGAGTTACATAACATAGCAATTGAATTTAATAAACCACAGTATTTCAGTATTATGGAGCTTCTTGA ATCAGTTGATATGATGGCACAAAATCTGCCATATAGGAAGTTCAAACCTGATGTGCCTCTTCACCACCATGCCAGAGAATGGTGGGCTTA TGCTATACATGGCGTTCTTGAAGTAAATGTTTGCCCCAGGTTATGGATGTGGTCATGGAAGCATATTAGAAAACATAGGCAAAAAGTGAA GCAATATAAAGAACTGTATAAAAAAAAGTTAACAAGTAAGAAGCCACCTGGTGAACTTCTCGTGTCTTTGGAGGAGTTGGAAAAAACCTT GGATGTCTTTAATATAACTATAGCTAGACAGACGGCAGAAGTTGAGGTAAAGAAAGCTGGATACAAAATTTACAAAGAAGGAGTAAAAGA TCCAGAGGATAATAAAGGGTGGTTTAGCTGGCTATGGTCTTGGTCAGAACAAAATACTAATGAACAGCAACCAGATGTTCAACCTGAAAC TCTTGAAGAAATGTTGACACCTGAAGAAAAAGCTTTACTCTATGAAGCAATTGGCTATAGTGAAACAGCAGTTGATCCAACTTTACTAAA AACATTTGAAGCCTTGAAGTTTTTTGTCCACTTGAAAAGTATGTCTATTGTTCTAAGAGAAAATCATCAAAAACCTGAGCTGGTAGATAT TGTAATAGAAGAATTTAGCACCTTAATTGTGCAAAGACCAGGAGCACAAGCAATAAAATTTGAAACTAAAATAGATTCATTTCATATTAC TGGCTTACCAGATAATTCAGAAAAACCCCGCCTCCTGTCTTCATTGGATGATGCAATGTCACTTTTCCAAATTACATTTGAGATAAATCC ATTAGATGAAACTGTTTCTCAGAGGTGTATCATAGAAGCTGAACCTTTAGAAATCATATATGATGCAAGGACAGTGAATAGTATAGTGGA ATTCTTCAGACCTCCAAAAGAGGTACATCTAGCACAGCTCACTGCAGCAACTTTGACAAAACTGGAAGAATTTCGCAGTAAGACAGCAAC AGGTCTACTGTATATTATTGAAACACAGAAAGTTCTTGATCTCAAAATTAATTTGAAGGCTTCATATATTATTGTCCCACAAGATGGAAT TTTTAGTCCTACATCAAATCTGCTTCTTTTGGACCTTGGTCATCTAAAGGTGACGAGTAAAAGTCGTTCTGAATTACCAGATGTGAAACA AGGTGAGGCCAATCTTAAAGAGATAATGGATAGAGCTTATGATTCATTTGATATTCAACTTACAAGTGTACAGCTGCTTTACAGTAGAGT TGGTGATAATTGGAGAGAAGCACGAAAACTCAGTGTATCTACCCAGCATATTTTGGTACCCATGCACTTCAATTTGGAACTGTCTAAGGC CATGGTTTTCATGGATGTAAGGATGCCCAAATTCAAGATTTATGGAAAGTTACCTCTTATTTCTTTACGAATCTCAGATAAAAAACTACA AGGGATTATGGAATTGATTGAAAGCATTCCAAAACCTGAACCAGTAACTGAAGTATCTGCCCCTGTCAAATCATTCCAGGTTCATGAAAG AAGTGTCCAGTCAGACTTCCTACTAATTATCTTGAAGGAAATTTTACAGAAACGTTCTGATCTACACTTGATTCTAATGAGTGCCACTGT GGACAGCGAAAAATTTTCTACATATTTCACACACTGCCCCATTCTCAGAATTTCAGGAAGAAGTTATCCTGTTGAGGTTTTTCATCTTGA AGATATAATAGAAGAAACAGGCTTTGTACTGGAAAAAGACTCAGAATATTGTCAGAAATTTCTGGAAGAGGAAGAAGAAGTAACCATTAA TGTTACAAGCAAAGCAGGGGGAATAAAAAAATATCAGGAATACATCCCAGTTCAGACTGGAGCACATGCTGATTTAAATCCATTTTACCA AAAGTACAGCAGCCGCACTCAGCATGCTATTCTATACATGAATCCTCATAAAATCAACCTGGATCTCATTTTGGAACTTCTTGCATACTT AGATAAAAGTCCCCAATTCAGAAATATTGAAGGAGCAGTATTGATCTTTTTACCAGGACTTGCTCATATTCAGCAGTTGTATGATCTTCT ATCAAATGATAGAAGATTTTATTCTGAACGATATAAAGTGATAGCTCTGCATTCTATTCTTTCAACCCAAGATCAAGCTGCAGCATTCAC ACTTCCCCCTCCAGGAGTCAGGAAGATTGTTTTAGCAACCAATATTGCAGAGACGGGTATCACTATTCCTGATGTTGTATTTGTAATTGA TACTGGAAGAACAAAAGAAAATAAGTACCATGAAAGCAGTCAGATGAGTTCTTTGGTGGAGACGTTTGTCAGTAAAGCCAGTGCTTTGCA GCGCCAGGGAAGAGCTGGGCGGGTCAGAGATGGCTTCTGTTTCCGAATGTACACAAGAGAAAGATTTGAAGGCTTTATGGATTATTCTGT TCCTGAAATCTTACGTGTACCTTTGGAGGAATTATGCCTTCATATTATGAAATGTAATCTTGGTTCTCCTGAAGATTTCCTCTCCAAAGC CTTAGATCCTCCTCAGCTCCAAGTGATCAGCAATGCAATGAATTTGCTCCGAAAAATTGGAGCTTGTGAATTAAATGAGCCTAAACTGAC TCCGTTGGGCCAACACCTTGCAGCTTTACCTGTGAATGTCAAGATTGGCAAGATGCTTATTTTTGGTGCCATATTTGGCTGCCTTGACCC AGTGGCAACACTAGCTGCAGTTATGACAGAGAAGTCTCCTTTTACCACACCAATTGGTCGAAAAGATGAAGCAGATCTTGCAAAATCAGC TTTGGCCATGGCGGATTCAGACCACCTGACGATCTACAATGCATATCTAGGATGGAAGAAAGCACGACAAGAAGGAGGTTATCGTTCTGA AATCACATACTGCCGGAGGAACTTTCTTAATAGAACATCACTGTTAACCCTAGAGGATGTAAAGCAGGAGTTAATAAAGTTGGTTAAGGC AGCAGGATTTTCATCTTCCACAACTTCTACCAGCTGGGAAGGAAACAGAGCCTCACAGACCCTCTCATTCCAAGAAATTGCCCTTCTTAA AGCTGTACTGGTGGCTGGACTGTATGACAATGTGGGGAAGATAATCTATACAAAGTCAGTGGATGTTACAGAAAAATTGGCTTGCATTGT GGAGACGGCCCAAGGCAAAGCACAAGTACACCCATCCTCAGTAAATCGAGATTTGCAAACTCATGGATGGCTCTTATACCAGGAGAAGAT AAGGTATGCCAGAGTGTATTTGAGAGAAACTACCCTAATAACCCCTTTTCCAGTTTTACTTTTTGGTGGTGATATAGAAGTTCAGCACCG AGAACGTCTTCTTTCTATTGATGGCTGGATCTATTTTCAGGCCCCTGTAAAGATAGCTGTCATTTTCAAGCAGCTGAGAGTTCTCATTGA TTCAGTTTTAAGAAAAAAGCTTGAAAATCCAAAGATGTCCCTTGAAAATGACAAGATTCTGCAGATCATTACGGAATTGATAAAAACAGA GAATAACTGAAACTGAAATTCATGGTCAACTGCTTTAAAAATTAAGATGAAGATACAGTCATGAAATTATCTGAAAATGGGTCATCACAT TAAGTATTTCATTACTTAAAATGTTGGTACTAGCCATTAACTTAAAGGTGGTGGGAAAAAAGCACATACTTTAAACATGTATAATTTTCT >98251_98251_3_VPS13A-DHX29_VPS13A_chr9_79875140_ENST00000376634_DHX29_chr5_54573110_ENST00000251636_length(amino acids)=1484AA_BP=818 MPCPPRLRNMVFESVVVDVLNRFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENALSQLDVPFKVKVGHIGNLKLIIPWKNLYTQPVEA VLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIEEAKQKVVDQEQHLPEKQDTFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDK PLSFGISLQNLSMQTTDQYWVPCLHDETEKLVRKLIRLDNLFAYWNVKSQMFYLSDYDNSLDDLKNGIVNENIVPEGYDFVFRPISANAK LVMNRRSDFDFSAPKINLEIELHNIAIEFNKPQYFSIMELLESVDMMAQNLPYRKFKPDVPLHHHAREWWAYAIHGVLEVNVCPRLWMWS WKHIRKHRQKVKQYKELYKKKLTSKKPPGELLVSLEELEKTLDVFNITIARQTAEVEVKKAGYKIYKEGVKDPEDNKGWFSWLWSWSEQN TNEQQPDVQPETLEEMLTPEEKALLYEAIGYSETAVDPTLLKTFEALKFFVHLKSMSIVLRENHQKPELVDIVIEEFSTLIVQRPGAQAI KFETKIDSFHITGLPDNSEKPRLLSSLDDAMSLFQITFEINPLDETVSQRCIIEAEPLEIIYDARTVNSIVEFFRPPKEVHLAQLTAATL TKLEEFRSKTATGLLYIIETQKVLDLKINLKASYIIVPQDGIFSPTSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRAYDSFDI QLTSVQLLYSRVGDNWREARKLSVSTQHILVPMHFNLELSKAMVFMDVRMPKFKIYGKLPLISLRISDKKLQGIMELIESIPKPEPVTEV SAPVKSFQVHERSVQSDFLLIILKEILQKRSDLHLILMSATVDSEKFSTYFTHCPILRISGRSYPVEVFHLEDIIEETGFVLEKDSEYCQ KFLEEEEEVTINVTSKAGGIKKYQEYIPVQTGAHADLNPFYQKYSSRTQHAILYMNPHKINLDLILELLAYLDKSPQFRNIEGAVLIFLP GLAHIQQLYDLLSNDRRFYSERYKVIALHSILSTQDQAAAFTLPPPGVRKIVLATNIAETGITIPDVVFVIDTGRTKENKYHESSQMSSL VETFVSKASALQRQGRAGRVRDGFCFRMYTRERFEGFMDYSVPEILRVPLEELCLHIMKCNLGSPEDFLSKALDPPQLQVISNAMNLLRK IGACELNEPKLTPLGQHLAALPVNVKIGKMLIFGAIFGCLDPVATLAAVMTEKSPFTTPIGRKDEADLAKSALAMADSDHLTIYNAYLGW KKARQEGGYRSEITYCRRNFLNRTSLLTLEDVKQELIKLVKAAGFSSSTTSTSWEGNRASQTLSFQEIALLKAVLVAGLYDNVGKIIYTK SVDVTEKLACIVETAQGKAQVHPSSVNRDLQTHGWLLYQEKIRYARVYLRETTLITPFPVLLFGGDIEVQHRERLLSIDGWIYFQAPVKI -------------------------------------------------------------- >98251_98251_4_VPS13A-DHX29_VPS13A_chr9_79875140_ENST00000376636_DHX29_chr5_54573110_ENST00000251636_length(transcript)=4931nt_BP=2687nt TTCCTCCCTCTCAGGGCTGCGCGCCCAGGTCTGCGCCGCGCTCCGCCTCCAGCCGCGCGCAGACTTGCGCACGCGTCGTGAGAGCGACCG CCTCCGTCTCTCGCTGGGCTCGCTAGGGCTGCGCGTTGGGCCAGCGGGGGCGCCGCAGCTGAAGCCGCCCCGGAGCCGGTGAACCGAATT ACCTCGAGGGAGGGGCGTGGGGAAGGCGGCGGGAGGAGGAGCGCACGGGCCGGCTGCCGTGCCCACCACGGCTGAGGAACATGGTTTTCG AGTCGGTGGTCGTGGACGTGTTGAACCGGTTCTTGGGGGACTATGTGGTGGACTTGGACACGTCCCAGCTCTCTCTGGGCATCTGGAAAG GAGCTGTGGCCCTCAAGAATCTTCAAATTAAAGAAAATGCCCTGAGTCAACTGGATGTACCATTTAAAGTTAAAGTTGGTCACATAGGTA ATCTTAAACTTATAATTCCATGGAAAAACCTTTATACTCAACCTGTTGAAGCCGTATTGGAAGAAATTTATTTACTTATAGTGCCTTCTT CTAGAATAAAATATGATCCTTTAAAAGAAGAGAAACAACTCATGGAAGCAAAGCAACAGGAACTGAAAAGAATAGAAGAAGCAAAACAAA AAGTAGTTGATCAAGAACAACATCTGCCGGAAAAACAGGACACTTTTGCAGAAAAATTAGTTACACAGATCATAAAAAATCTTCAGGTGA AAATTTCCAGTATCCATATTCGTTATGAAGATGATATCACAAATCGGGACAAACCGCTGTCATTTGGTATTTCCCTTCAAAATCTGAGCA TGCAGACAACTGATCAATACTGGGTTCCATGTTTACATGATGAAACTGAGAAACTGGTTCGTAAGTTAATCCGATTGGATAACCTGTTTG CCTATTGGAATGTGAAGTCTCAGATGTTTTATCTTAGTGATTATGATAACTCCTTGGACGACTTGAAGAATGGCATTGTCAATGAAAATA TTGTTCCAGAAGGTTATGATTTTGTATTTCGTCCCATATCTGCTAATGCCAAACTTGTGATGAATCGCCGATCTGATTTTGACTTTTCTG CCCCCAAAATAAACTTGGAAATTGAGTTACATAACATAGCAATTGAATTTAATAAACCACAGTATTTCAGTATTATGGAGCTTCTTGAAT CAGTTGATATGATGGCACAAAATCTGCCATATAGGAAGTTCAAACCTGATGTGCCTCTTCACCACCATGCCAGAGAATGGTGGGCTTATG CTATACATGGCGTTCTTGAAGTAAATGTTTGCCCCAGGTTATGGATGTGGTCATGGAAGCATATTAGAAAACATAGGCAAAAAGTGAAGC AATATAAAGAACTGTATAAAAAAAAGTTAACAAGTAAGAAGCCACCTGGTGAACTTCTCGTGTCTTTGGAGGAGTTGGAAAAAACCTTGG ATGTCTTTAATATAACTATAGCTAGACAGACGGCAGAAGTTGAGGTAAAGAAAGCTGGATACAAAATTTACAAAGAAGGAGTAAAAGATC CAGAGGATAATAAAGGGTGGTTTAGCTGGCTATGGTCTTGGTCAGAACAAAATACTAATGAACAGCAACCAGATGTTCAACCTGAAACTC TTGAAGAAATGTTGACACCTGAAGAAAAAGCTTTACTCTATGAAGCAATTGGCTATAGTGAAACAGCAGTTGATCCAACTTTACTAAAAA CATTTGAAGCCTTGAAGTTTTTTGTCCACTTGAAAAGTATGTCTATTGTTCTAAGAGAAAATCATCAAAAACCTGAGCTGGTAGATATTG TAATAGAAGAATTTAGCACCTTAATTGTGCAAAGACCAGGAGCACAAGCAATAAAATTTGAAACTAAAATAGATTCATTTCATATTACTG GCTTACCAGATAATTCAGAAAAACCCCGCCTCCTGTCTTCATTGGATGATGCAATGTCACTTTTCCAAATTACATTTGAGATAAATCCAT TAGATGAAACTGTTTCTCAGAGGTGTATCATAGAAGCTGAACCTTTAGAAATCATATATGATGCAAGGACAGTGAATAGTATAGTGGAAT TCTTCAGACCTCCAAAAGAGGTACATCTAGCACAGCTCACTGCAGCAACTTTGACAAAACTGGAAGAATTTCGCAGTAAGACAGCAACAG GTCTACTGTATATTATTGAAACACAGAAAGTTCTTGATCTCAAAATTAATTTGAAGGCTTCATATATTATTGTCCCACAAGATGGAATTT TTAGTCCTACATCAAATCTGCTTCTTTTGGACCTTGGTCATCTAAAGGTGACGAGTAAAAGTCGTTCTGAATTACCAGATGTGAAACAAG GTGAGGCCAATCTTAAAGAGATAATGGATAGAGCTTATGATTCATTTGATATTCAACTTACAAGTGTACAGCTGCTTTACAGTAGAGTTG GTGATAATTGGAGAGAAGCACGAAAACTCAGTGTATCTACCCAGCATATTTTGGTACCCATGCACTTCAATTTGGAACTGTCTAAGGCCA TGGTTTTCATGGATGTAAGGATGCCCAAATTCAAGATTTATGGAAAGTTACCTCTTATTTCTTTACGAATCTCAGATAAAAAACTACAAG GGATTATGGAATTGATTGAAAGCATTCCAAAACCTGAACCAGTAACTGAAGTATCTGCCCCTGTCAAATCATTCCAGGTTCATGAAAGAA GTGTCCAGTCAGACTTCCTACTAATTATCTTGAAGGAAATTTTACAGAAACGTTCTGATCTACACTTGATTCTAATGAGTGCCACTGTGG ACAGCGAAAAATTTTCTACATATTTCACACACTGCCCCATTCTCAGAATTTCAGGAAGAAGTTATCCTGTTGAGGTTTTTCATCTTGAAG ATATAATAGAAGAAACAGGCTTTGTACTGGAAAAAGACTCAGAATATTGTCAGAAATTTCTGGAAGAGGAAGAAGAAGTAACCATTAATG TTACAAGCAAAGCAGGGGGAATAAAAAAATATCAGGAATACATCCCAGTTCAGACTGGAGCACATGCTGATTTAAATCCATTTTACCAAA AGTACAGCAGCCGCACTCAGCATGCTATTCTATACATGAATCCTCATAAAATCAACCTGGATCTCATTTTGGAACTTCTTGCATACTTAG ATAAAAGTCCCCAATTCAGAAATATTGAAGGAGCAGTATTGATCTTTTTACCAGGACTTGCTCATATTCAGCAGTTGTATGATCTTCTAT CAAATGATAGAAGATTTTATTCTGAACGATATAAAGTGATAGCTCTGCATTCTATTCTTTCAACCCAAGATCAAGCTGCAGCATTCACAC TTCCCCCTCCAGGAGTCAGGAAGATTGTTTTAGCAACCAATATTGCAGAGACGGGTATCACTATTCCTGATGTTGTATTTGTAATTGATA CTGGAAGAACAAAAGAAAATAAGTACCATGAAAGCAGTCAGATGAGTTCTTTGGTGGAGACGTTTGTCAGTAAAGCCAGTGCTTTGCAGC GCCAGGGAAGAGCTGGGCGGGTCAGAGATGGCTTCTGTTTCCGAATGTACACAAGAGAAAGATTTGAAGGCTTTATGGATTATTCTGTTC CTGAAATCTTACGTGTACCTTTGGAGGAATTATGCCTTCATATTATGAAATGTAATCTTGGTTCTCCTGAAGATTTCCTCTCCAAAGCCT TAGATCCTCCTCAGCTCCAAGTGATCAGCAATGCAATGAATTTGCTCCGAAAAATTGGAGCTTGTGAATTAAATGAGCCTAAACTGACTC CGTTGGGCCAACACCTTGCAGCTTTACCTGTGAATGTCAAGATTGGCAAGATGCTTATTTTTGGTGCCATATTTGGCTGCCTTGACCCAG TGGCAACACTAGCTGCAGTTATGACAGAGAAGTCTCCTTTTACCACACCAATTGGTCGAAAAGATGAAGCAGATCTTGCAAAATCAGCTT TGGCCATGGCGGATTCAGACCACCTGACGATCTACAATGCATATCTAGGATGGAAGAAAGCACGACAAGAAGGAGGTTATCGTTCTGAAA TCACATACTGCCGGAGGAACTTTCTTAATAGAACATCACTGTTAACCCTAGAGGATGTAAAGCAGGAGTTAATAAAGTTGGTTAAGGCAG CAGGATTTTCATCTTCCACAACTTCTACCAGCTGGGAAGGAAACAGAGCCTCACAGACCCTCTCATTCCAAGAAATTGCCCTTCTTAAAG CTGTACTGGTGGCTGGACTGTATGACAATGTGGGGAAGATAATCTATACAAAGTCAGTGGATGTTACAGAAAAATTGGCTTGCATTGTGG AGACGGCCCAAGGCAAAGCACAAGTACACCCATCCTCAGTAAATCGAGATTTGCAAACTCATGGATGGCTCTTATACCAGGAGAAGATAA GGTATGCCAGAGTGTATTTGAGAGAAACTACCCTAATAACCCCTTTTCCAGTTTTACTTTTTGGTGGTGATATAGAAGTTCAGCACCGAG AACGTCTTCTTTCTATTGATGGCTGGATCTATTTTCAGGCCCCTGTAAAGATAGCTGTCATTTTCAAGCAGCTGAGAGTTCTCATTGATT CAGTTTTAAGAAAAAAGCTTGAAAATCCAAAGATGTCCCTTGAAAATGACAAGATTCTGCAGATCATTACGGAATTGATAAAAACAGAGA ATAACTGAAACTGAAATTCATGGTCAACTGCTTTAAAAATTAAGATGAAGATACAGTCATGAAATTATCTGAAAATGGGTCATCACATTA AGTATTTCATTACTTAAAATGTTGGTACTAGCCATTAACTTAAAGGTGGTGGGAAAAAAGCACATACTTTAAACATGTATAATTTTCTAG >98251_98251_4_VPS13A-DHX29_VPS13A_chr9_79875140_ENST00000376636_DHX29_chr5_54573110_ENST00000251636_length(amino acids)=1484AA_BP=818 MPCPPRLRNMVFESVVVDVLNRFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENALSQLDVPFKVKVGHIGNLKLIIPWKNLYTQPVEA VLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIEEAKQKVVDQEQHLPEKQDTFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDK PLSFGISLQNLSMQTTDQYWVPCLHDETEKLVRKLIRLDNLFAYWNVKSQMFYLSDYDNSLDDLKNGIVNENIVPEGYDFVFRPISANAK LVMNRRSDFDFSAPKINLEIELHNIAIEFNKPQYFSIMELLESVDMMAQNLPYRKFKPDVPLHHHAREWWAYAIHGVLEVNVCPRLWMWS WKHIRKHRQKVKQYKELYKKKLTSKKPPGELLVSLEELEKTLDVFNITIARQTAEVEVKKAGYKIYKEGVKDPEDNKGWFSWLWSWSEQN TNEQQPDVQPETLEEMLTPEEKALLYEAIGYSETAVDPTLLKTFEALKFFVHLKSMSIVLRENHQKPELVDIVIEEFSTLIVQRPGAQAI KFETKIDSFHITGLPDNSEKPRLLSSLDDAMSLFQITFEINPLDETVSQRCIIEAEPLEIIYDARTVNSIVEFFRPPKEVHLAQLTAATL TKLEEFRSKTATGLLYIIETQKVLDLKINLKASYIIVPQDGIFSPTSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRAYDSFDI QLTSVQLLYSRVGDNWREARKLSVSTQHILVPMHFNLELSKAMVFMDVRMPKFKIYGKLPLISLRISDKKLQGIMELIESIPKPEPVTEV SAPVKSFQVHERSVQSDFLLIILKEILQKRSDLHLILMSATVDSEKFSTYFTHCPILRISGRSYPVEVFHLEDIIEETGFVLEKDSEYCQ KFLEEEEEVTINVTSKAGGIKKYQEYIPVQTGAHADLNPFYQKYSSRTQHAILYMNPHKINLDLILELLAYLDKSPQFRNIEGAVLIFLP GLAHIQQLYDLLSNDRRFYSERYKVIALHSILSTQDQAAAFTLPPPGVRKIVLATNIAETGITIPDVVFVIDTGRTKENKYHESSQMSSL VETFVSKASALQRQGRAGRVRDGFCFRMYTRERFEGFMDYSVPEILRVPLEELCLHIMKCNLGSPEDFLSKALDPPQLQVISNAMNLLRK IGACELNEPKLTPLGQHLAALPVNVKIGKMLIFGAIFGCLDPVATLAAVMTEKSPFTTPIGRKDEADLAKSALAMADSDHLTIYNAYLGW KKARQEGGYRSEITYCRRNFLNRTSLLTLEDVKQELIKLVKAAGFSSSTTSTSWEGNRASQTLSFQEIALLKAVLVAGLYDNVGKIIYTK SVDVTEKLACIVETAQGKAQVHPSSVNRDLQTHGWLLYQEKIRYARVYLRETTLITPFPVLLFGGDIEVQHRERLLSIDGWIYFQAPVKI -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for VPS13A-DHX29 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for VPS13A-DHX29 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for VPS13A-DHX29 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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