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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:VPS13D-PITPNB (FusionGDB2 ID:98331)

Fusion Gene Summary for VPS13D-PITPNB

Fusion gene summary

Fusion gene information	Fusion gene name: VPS13D-PITPNB
	Fusion gene ID: 98331
		Hgene	Tgene
	Gene symbol	VPS13D	PITPNB
	Gene ID	55187	23760
	Gene name	vacuolar protein sorting 13 homolog D	phosphatidylinositol transfer protein beta
	Synonyms	SCAR4	PI-TP-beta\|PtdInsTP\|VIB1B
	Cytomap	1p36.22-p36.21	22q12.1
	Type of gene	protein-coding	protein-coding
	Description	vacuolar protein sorting-associated protein 13Dvacuolar protein sorting 13D	phosphatidylinositol transfer protein beta isoformPtdIns transfer protein betaphosphotidylinositol transfer protein, beta
	Modification date	20200313	20200313
	UniProtAcc	.	.
	Ensembl transtripts involved in fusion gene	ENST00000496628, ENST00000356315, ENST00000358136, ENST00000543766, ENST00000471923, ENST00000543710,	ENST00000320996, ENST00000335272, ENST00000455418,
Fusion gene scores	* DoF score	11 X 11 X 7=847	7 X 8 X 7=392
	# samples	11	10
	** MAII score	log2(11/847*10)=-2.94485844580754 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(10/392*10)=-1.97085365434048 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: VPS13D [Title/Abstract] AND PITPNB [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	VPS13D(12476754)-PITPNB(28254502), # samples:1
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Tgene	PITPNB	GO:0015914	phospholipid transport	16274224

Fusion gene breakpoints across VPS13D (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across PITPNB (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChiTaRS5.0	N/A	BF741687	VPS13D	chr1	12476754	-	PITPNB	chr22	28254502	-

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Fusion Gene ORF analysis for VPS13D-PITPNB

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
3UTR-3CDS	ENST00000496628	ENST00000320996	VPS13D	chr1	12476754	-	PITPNB	chr22	28254502	-
3UTR-3CDS	ENST00000496628	ENST00000335272	VPS13D	chr1	12476754	-	PITPNB	chr22	28254502	-
3UTR-3CDS	ENST00000496628	ENST00000455418	VPS13D	chr1	12476754	-	PITPNB	chr22	28254502	-
In-frame	ENST00000356315	ENST00000320996	VPS13D	chr1	12476754	-	PITPNB	chr22	28254502	-
In-frame	ENST00000356315	ENST00000335272	VPS13D	chr1	12476754	-	PITPNB	chr22	28254502	-
In-frame	ENST00000356315	ENST00000455418	VPS13D	chr1	12476754	-	PITPNB	chr22	28254502	-
In-frame	ENST00000358136	ENST00000320996	VPS13D	chr1	12476754	-	PITPNB	chr22	28254502	-
In-frame	ENST00000358136	ENST00000335272	VPS13D	chr1	12476754	-	PITPNB	chr22	28254502	-
In-frame	ENST00000358136	ENST00000455418	VPS13D	chr1	12476754	-	PITPNB	chr22	28254502	-
In-frame	ENST00000543766	ENST00000320996	VPS13D	chr1	12476754	-	PITPNB	chr22	28254502	-
In-frame	ENST00000543766	ENST00000335272	VPS13D	chr1	12476754	-	PITPNB	chr22	28254502	-
In-frame	ENST00000543766	ENST00000455418	VPS13D	chr1	12476754	-	PITPNB	chr22	28254502	-
intron-3CDS	ENST00000471923	ENST00000320996	VPS13D	chr1	12476754	-	PITPNB	chr22	28254502	-
intron-3CDS	ENST00000471923	ENST00000335272	VPS13D	chr1	12476754	-	PITPNB	chr22	28254502	-
intron-3CDS	ENST00000471923	ENST00000455418	VPS13D	chr1	12476754	-	PITPNB	chr22	28254502	-
intron-3CDS	ENST00000543710	ENST00000320996	VPS13D	chr1	12476754	-	PITPNB	chr22	28254502	-
intron-3CDS	ENST00000543710	ENST00000335272	VPS13D	chr1	12476754	-	PITPNB	chr22	28254502	-
intron-3CDS	ENST00000543710	ENST00000455418	VPS13D	chr1	12476754	-	PITPNB	chr22	28254502	-

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000358136	VPS13D	chr1	12476754	-	ENST00000335272	PITPNB	chr22	28254502	-	14625	12421	130	12591	4153
ENST00000358136	VPS13D	chr1	12476754	-	ENST00000320996	PITPNB	chr22	28254502	-	14538	12421	130	12594	4154
ENST00000358136	VPS13D	chr1	12476754	-	ENST00000455418	PITPNB	chr22	28254502	-	14622	12421	130	12591	4153
ENST00000356315	VPS13D	chr1	12476754	-	ENST00000335272	PITPNB	chr22	28254502	-	14550	12346	130	12516	4128
ENST00000356315	VPS13D	chr1	12476754	-	ENST00000320996	PITPNB	chr22	28254502	-	14463	12346	130	12519	4129
ENST00000356315	VPS13D	chr1	12476754	-	ENST00000455418	PITPNB	chr22	28254502	-	14547	12346	130	12516	4128
ENST00000543766	VPS13D	chr1	12476754	-	ENST00000335272	PITPNB	chr22	28254502	-	2489	285	0	455	151
ENST00000543766	VPS13D	chr1	12476754	-	ENST00000320996	PITPNB	chr22	28254502	-	2402	285	0	458	152
ENST00000543766	VPS13D	chr1	12476754	-	ENST00000455418	PITPNB	chr22	28254502	-	2486	285	0	455	151

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000358136	ENST00000335272	VPS13D	chr1	12476754	-	PITPNB	chr22	28254502	-	0.00051192	0.9994881
ENST00000358136	ENST00000320996	VPS13D	chr1	12476754	-	PITPNB	chr22	28254502	-	0.000360792	0.99963915
ENST00000358136	ENST00000455418	VPS13D	chr1	12476754	-	PITPNB	chr22	28254502	-	0.000507022	0.999493
ENST00000356315	ENST00000335272	VPS13D	chr1	12476754	-	PITPNB	chr22	28254502	-	0.000490407	0.9995096
ENST00000356315	ENST00000320996	VPS13D	chr1	12476754	-	PITPNB	chr22	28254502	-	0.000345223	0.99965477
ENST00000356315	ENST00000455418	VPS13D	chr1	12476754	-	PITPNB	chr22	28254502	-	0.000485687	0.99951434
ENST00000543766	ENST00000335272	VPS13D	chr1	12476754	-	PITPNB	chr22	28254502	-	0.004419421	0.9955806
ENST00000543766	ENST00000320996	VPS13D	chr1	12476754	-	PITPNB	chr22	28254502	-	0.003284906	0.99671507
ENST00000543766	ENST00000455418	VPS13D	chr1	12476754	-	PITPNB	chr22	28254502	-	0.004544556	0.9954554

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Fusion Genomic Features for VPS13D-PITPNB

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for VPS13D-PITPNB

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:12476754/chr22:28254502)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	.
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

VPS13D

chr1:12476754

chr22:28254502

ENST00000356315

2633_2676

4364.0

Domain

UBA

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Fusion Gene Sequence for VPS13D-PITPNB

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>98331_98331_1_VPS13D-PITPNB_VPS13D_chr1_12476754_ENST00000356315_PITPNB_chr22_28254502_ENST00000320996_length(transcript)=14463nt_BP=12346nt
GGAGGAAACGCCGCGCAGCGCCGGGCTGGGGCGGGCGGCCCGGGACACCGACAGATTTTTCTGTGACCATGAAAGAGAGAAATAAAGAAT
GATCCATGATTTCTAAACACCTTTTCCTGAGGATATAGTCATGTTGGAAGGCCTTGTAGCCTGGGTTCTCAATACCTATTTGGGAAAATA
TGTCAATAACCTGAACACTGACCAGCTCTCAGTTGCACTTCTCAAAGGTGCTGTTGAATTAGAAAACTTGCCATTAAAGAAAGATGCCTT
GAAAGAATTGGAATTACCATTTGAAGTCAAAGCTGGCTTCATTGGGAAAGTAACCCTTCAGATTCCCTTTTATCGCCCCCATGTGGACCC
TTGGGTGATCTCCATCTCCAGCCTTCACTTAATTGGAGCCCCAGAGAAAATACAGGATTTCAATGATGAAAAGGAGAAGCTGTTGGAAAG
GGAACGTAAGAAAGCACTACTTCAAGCCCTGGAGGAGAAATGGAAGAATGACCGCCAGCAGAAAGGGGAGTCCTATTGGTATTCAGTTAC
CGCCTCCGTAGTTACAAGGATTGTGGAGAATATTGAATTAAAAATTCAAGATGTCCATTTACGCTTTGAAGATGGTGTCACCAATCCCTC
CCATCCTTTTGCTTTTGGCATCTGCATTAAGAATGTGTCCATGCAAAATGCTGTGAATGAGCCTGTACAGAAACTAATGCGGAAAAAGCA
ATTAGACGTAGCAGAATTTAGCATCTATTGGGATGTCGATTGCACTTTACTGGGGGATTTGCCTCAGATGGAGTTACAGGAGGCCATGGC
CAGGAGCATGGAGAGTCGCAGCCATCACTACGTCCTGGAGCCTGTGTTTGCATCTGCTCTTTTGAAGAGAAACTGCTCCAAGAAGCCCCT
GCGGTCTCGGCACAGTCCCCGTATTGATTGTGATATTCAGCTGGAGACCATTCCCTTGAAACTCTCTCAGCTGCAATACCGGCAAATCAT
GGAATTCCTCAAGGAGCTGGAACGAAAGGAGAGGCAGGTGAAGTTCCGAAGGTGGAAACCCAAGGTGGCGATATCTAAGAACTGCCGAGA
ATGGTGGTATTTTGCTTTGAATGCTAACTTGTATGAGATCAGAGAGCAGAGGAAACGTTGCACCTGGGACTTTATGTTGCACCGCGCTCG
TGATGCTGTATCTTACACTGACAAATATTTCAACAAGTTAAAAGGAGGCCTGCTGTCCACAGATGACAAGGAGGAAATGTGTCGGATTGA
AGAGGAACAGAGCTTTGAGGAATTGAAGATTTTGCGTGAACTGGTTCATGATCGATTTCACAAACAGGAAGAACTAGCAGAGAGTCTGCG
GGAGCCTCAGTTTGATTCTCCAGGAGCCTGTCCGGGAGCCCCAGAACCCGGTGGAGGCAGTGGGATGCTGCAGTATCTCCAGTCCTGGTT
TCCTGGATGGGGTGGCTGGTACGGGCAGCAGACCCCAGAAGGGAATGTGGTTGAGGGACTGTCAGCAGAGCAACAGGAGCAGTGGATTCC
TGAAGAGATCCTGGGCACTGAGGAGTTTTTTGACCCCACTGCAGATGCCTCGTGTATGAACACGTATACAAAGCGAGATCATGTCTTTGC
CAAACTGAATTTGCAGTTGCAGCGAGGTACAGTGACTCTGTTACACAAGGAGCAAGGAACTCCTCAAATGAATGAAAGTGCTTTCATGCA
GCTCGAGTTTTCAGATGTAAAACTTCTAGCAGAGTCTCTTCCTCGAAGAAATTCCTCGTTGCTTTCAGTCCGGTTGGGTGGACTGTTTCT
TCGAGACCTGGCTACAGAAGGAACTATGTTTCCTCTTCTAGTCTTCCCTAATCCACAAAAAGAAGTTGGCAGAGTCTCACAATCTTTTGG
TCTACAAACTACATCTGCAGACAGAAGTGATCATTACCCAGCTGCAGATCCAGATGGCCCCGTTTTTGAGATGCTGTATGAGAGAAATCC
GGCGCACAGCCACTTTGAGAGGCGGCTCAATGTCAGCACAAGGCCCTTGAACATCATATACAATCCGCAGGCCATTAAAAAAGTAGCAGA
CTTTTTCTACAAGGGAAAGGTTCATACCTCAGGTTTTGGTTATCAGTCTGAACTTGAGCTGAGAGTGGCTGAAGCTGCCCGAAGACAATA
TAACAAGCTGAAGATGCAGACCAAGGCAGAAATCCGGCAAACTCTTGATCGTTTGCTAGTGGGTGATTTCATTGAGGAGAGTAAACGATG
GACCGTGCGGCTGGATATTTCTGCCCCTCAGGTGATATTTCCTGATGATTTCAAATTCAAGAATCCTGTGTTAGTTGTCGTGGATCTAGG
AAGAATGCTTTTGACGAACACCCAAGATAACTCCAGGAGGAAAAGTAGGGATGGGTCAGCATCTGAAGAGACCCAGTTTAGTGATGATGA
ATATAAGACCCCCCTGGCCACACCTCCTAACACCCCACCTCCCGAGTCAAGCAGCAGCAACGGAGAGAAAACACCTCCCTTTTCTGGAGT
TGAGTTCAGTGAAGAACAGCTTCAAGCACATTTAATGAGCACAAAGATGTATGAGAGGTACTCGCTGTCATTTATGGACCTCCAGATCAT
GGTTGGACGAGTGAAAGACAATTGGAAGCATGTCCAGGATATTGACGTGGGACCAACACATGTGGTAGAGAAGTTCAACGTTCACCTACA
GTTAGAGCGTCGATTGATTTATACTTCAGATCCCAAATATCCAGGAGCCGTGCTCTCAGGCAACTTACCAGACTTAAAAATCCACATTAA
TGAAGATAAAATATCTGCACTAAAGAATTGCTTTGCTCTCCTCACCACCCCAGAAATGAAAACTTCTGACACTCAGATTAAAGAAAAGAT
TTTTCCCCAGGAGGAGCAGCGGGGAAGTTTGCAAGACTCCGTAATGAATTTAACCCAGAGCATTGTGTTGTTGGAGCAGCATACCCGCGA
GGTTCTGGTGGAGTCGCAGCTCCTCCTGGCGGAATTTAAAGTGAACTGTATGCAGCTTGGTGTTGAGAGCAATGGCCGGTACATTTCTGT
GCTCAAGGTGTTTGGTACCAATGCTCACTTTGTGAAGAGGCCTTATGATGCTGAAGTCTCCCTAACTGTTCATGGTTTGCTCCTGGTGGA
TACCATGCAGACATATGGTGCTGATTTTGACCTTTTGATGGCTTCACATAAGAACTTGAGCTTTGATATTCCAACGGGAAGCCTTCGGGA
TAGCAGGGCCCAGTCTCCTGTCTCTGGACCGAATGTGGCCCACTTAACTGATGGAGCTACACTGAACGACCGATCAGCTACTAGTGTTTC
ACTTGACAAAATTCTTACCAAAGAGCAAGAGTCCCTTATTAAGTTGGAATATCAGTTTGTGAGTTCAGAGTGCCCATCGATGAATTTAGA
CAGTACTCTTCAGGTGATTTCCCTACAGGTGAATAATTTAGATATTATCCTCAATCCAGAGACGATTGTGGAGCTAATTGGTTTTCTTCA
AAAATCCTTTCCCAAGGAAAAAGATGATTTAAGTCCTCAACCTTTAATGACTGATTTTGAAAGAAGCTTCAGAGAACAAGGAACTTACCA
GTCTACATATGAACAAAACACTGAGGTTGCAGTGGAAATCCATAGGCTGAACTTACTGCTTCTTCGGACAGTGGGCATGGCAAATAGAGA
GAAATATGGCAGAAAAATTGCAACTGCAAGTATAGGTGGCACCAAAGTTAATGTCTCAATGGGTAGCACGTTTGACATGAATGGTTCTCT
TGGCTGTTTACAGCTTATGGATTTGACACAAGATAACGTTAAAAACCAGTATGTTGTCAGCATTGGGAATTCTGTAGGCTATGAAAATAT
CATCAGTGATATTGGCTACTTTGAATCTGTGTTTGTCAGAATGGAAGATGCAGCCCTCACTGAAGCTTTGAGTTTCACGTTTGTTGAGAG
ATCTAAACAGGAGTGTTTTCTCAACCTGAAGATGGCTTCTTTACATTATAACCACTCTGCTAAGTTTTTGAAGGAGTTGACGTTATCCAT
GGATGAACTGGAAGAAAATTTTCGAGGTATGCTGAAAAGCGCAGCCACCAAAGTCACCACAGTACTAGCTACCAAGACTGCCGAGTATAG
CGAGATGGTATCGCTCTTTGAAACTCCAAGGAAGACTCGGGAACCCTTTATCTTAGAGGAAAATGAAATATATGGGTTTGACCTAGCTTC
GTCTCATTTGGACACTGTAAAGCTAATCTTGAACATAAACATTGAATCACCAGTTGTTTCTATCCCTCGGAAGCCGGGGAGTCCTGAGTT
GTTGGTGGGACACTTGGGACAGATATTCATCCAGAATTTTGTGGCGGGAGATGATGAATCCAGAAGTGACCGTCTGCAGGTGGAAATCAA
GGACATTAAACTGTATTCTTTGAATTGCACCCAGTTGGCAGGTAGAGAAGCTGTTGGGTCTGAAGGAAGCCGGATGTTTTGCCCACCTTC
CGGGTCTGGCAGTGCCAACAGTCAGGAGGAAGCTCATTTCACACGACATGATTTCTTTGAATCTTTGCATAGAGGTCAAGCTTTTCACAT
CCTGAACAACACCACCATTCAGTTTAAACTGGAGAAGATCCCTATAGAGAGAGAATCTGAATTGACTTTTTCTCTTAGCCCAGATGACCT
GGGAACTTCTAGCATCATGAAGATTGAAGGAAAATTTGTCAATCCAGTTCAGGTGGTGTTAGCAAAGCATGTATATGAGCAGGTTTTACA
AACCCTGGACAATCTCGTGTACAGTGAAGATCTGAATAAGTATCCAGCCAGTGCTACCTCCTCCCCTTGCCCTGATTCTCCTCTGCCTCC
CCTCAGTACCTGTGGAGAATCTTCTGTTGAAAGGAAGGAGAATGGATTGTTCAGCCACTCCAGCCTTTCTAACACCTCTCAGAAGTCATT
GTCAGTGAAGGAAGTCAAATCCTTTACTCAGATTCAAGCCACCTTTTGTATATCAGAGCTTCAGGTTCAGCTAAGTGGAGATCTGACTTT
GGGGGCCCAAGGTCTTGTGAGCTTAAAGTTTCAGGACTTTGAGGTGGAATTCAGTAAAGACCATCCCCAGACTTTATCTATTCAGATTGC
CCTGCATTCTCTGCTGATGGAGGACTTATTGGAGAAGAATCCAGATTCTAAATATAAGAACCTGATGGTGTCTCGAGGAGCCCCTAAGCC
ATCTAGTTTAGCACAAAAAGAATACCTTTCTCAGTCTTGCCCCTCAGTGTCCAATGTGGAATATCCTGATATGCCTCGGTCTCTCCCTTC
CCACATGGAAGAAGCTCCTAATGTCTTCCAGTTGTATCAAAGGCCCACCTCTGCGTCCCGGAAAAAGCAAAAGGAAGTCCAAGACAAGGA
CTATCCCTTGACCCCACCTCCTTCTCCAACAGTGGATGAGCCCAAGATACTTGTTGGAAAGAGTAAATTTGATGATTCCTTAGTCCACAT
CAACATATTCTTGGTAGATAAGAAACATCCAGAATTCTCTTCCAGTTACAATCGAGTTAACCGGAGCATTGATGTTGATTTTAATTGCTT
GGATGTGCTGATCACACTGCAAACCTGGGTTGTGATATTAGACTTTTTTGGAATCGGCTCCACTGCAGACAACCACGCAATGAGGCTGCC
TCCTGAGGGCATTCTGCACAACGTGAAGTTGGAGCCACATGCCTCCATGGAGTCTGGACTTCAGGATCCAGTGAACACCAAACTGGATCT
CAAGGTTCATTCACTTTCTCTAGTGCTGAATAAGACCACCAGTGAGCTTGCCAAAGCAAATGTGTCCAAATTAGTAGCACACCTGGAAAT
GATTGAGGGAGACCTGGCCTTACAGGGCAGCATTGGGAGTCTGTCTCTAAGTGACCTCACATGCCATGGAGAGTTCTACAGAGAACGGTT
CACTACCAGTGGTGAAGAAGCACTCATCTTCCAGACTTTTAAATACGGACGGCCTGACCCTCTGCTCCGGAGAGAACACGACATTCGCGT
GAGCCTCCGGATGGCCTCTGTGCAGTATGTGCATACTCAGCGTTTCCAGGCAGAGGTGGTGGCCTTCATTCAGCATTTCACTCAGCTGCA
GGATGTCTTAGGGCGCCAGCGAGCTGCTATTGAGGGGCAGACGGTGAGAGATCAAGCCCAGCGCTGTTCACGGGTTCTCCTGGATATTGA
GGCTGGTGCTCCCGTTCTCTTGATCCCAGAAAGTTCCAGATCAAATAATCTGATTGTAGCAAATTTGGGGAAGTTGAAAGTCAAAAATAA
GTTTCTGTTTGCTGGTTTTCCTGGCACCTTTTCCCTACAAGATAAGGAATCTGTGCCTTCAGCTTCCCCAACGGGTATTCCCAAACACAG
TCTGAGGAAAACGACAAGCACGGAGGAGCCCAGGGGAACCCATTCCCAGGGGCAGTTCACGATGCCTCTTGCTGGAATGAGCCTAGGAAG
CCTGAAGAGTGAGTTTGTGCCCAGTACCTCCACCAAGCAGCAAGGGCCGCAACCCACACTGTCTGTTGGCCAAGAGTCCAGTAGTCCAGA
AGACCATGTCTGCCTGCTGGATTGCGTTGTCGTGGATCTCCAGGACATGGACATCTTTGCTGCAGAGAGACATCCGAGAGAATACTCGAA
GGCACCAGAGGATAGTAGTGGAGATCTGATCTTCCCTTCCTATTTTGTGCGACAGACAGGAGGAAGCCTCTTAACCGAGCCTTGTAGGCT
GAAATTGCAGGTGGAAAGGAATTTGGACAAAGAAATAAGTCATACTGTGCCAGACATATCTATCCATGGCAATCTCTCCTCAGTCCACTG
CTCTCTGGATCTGTATAAATACAAGCTGATCCGCGGCTTATTAGAGAACAACCTGGGAGAACCCATAGAGGAATTTATGCGGCCTTATGA
TTTACAAGATCCAAGAATTCATACTGTCCTGAGTGGAGAAGTGTACACCTGTATGTGCTTCCTCATTGATATGGTGAATGTAAGTCTGGA
GCTTAAAGATCCAAAAAGAAAAGAAGGTGCTGGGTCCCTAGCCAGATTTGACTTCAAGAAATGCAAACTGCTCTATGAAAGTTTTTCCAA
CCAAACCAAGTCCATTAACTTGGTTTCCCATTCCATGATGGCTTTTGACACCCGTTATGCTGGGCAGAAGACCAGCCCTGGCATGACGAA
TGTGTTCAGCTGTATCTTTCAGCCCGCTAAGAACAGCAGCACCACCCAAGGGTCCATTCAGATTGAACTACATTTCAGATCTACCAAGGA
TTCCTCCTGCTTTACAGTAGTTCTCAACAATCTCCGTGTGTTTCTCATATTTGACTGGCTACTGTTAGTCCATGATTTTCTCCACACTCC
CAGTGATATTAAGAAACAAAATCATGTTACTCCTTCTCGCCACCGTAACTCTAGCAGCGAATCTGCTATAGTTCCCAAAACTGTGAAGAG
TGGAGTAGTTACCAAGCGGTCTTCCCTTCCTGTGTCCAATGAAAGGCACCTGGAGGTCAAGGTCAATGTAACAGGTACGGAGTTTGTGGT
CATTGAAGATGTGTCCTGCTTCGACACCAATGCCATTATTCTGAAAGGCACCACAGTGCTCACCTATAAGCCCCGGTTTGTTGATCGCCC
CTTTTCAGGAAGTTTGTTTGGCATTGAGGTGTTTTCATGCCGACTAGGGAATGAGCATGATACAGCTCTTTCAATTGTGGATCCCGTACA
AATTCAAATGGAGTTGGTGGGGAATTCTTCTTATCAAAATAGTTCAGGATTGATGGATGCATTCAATAGTGAAGATTTCCCACCTGTCCT
GGAGATTCAGTTACAAGCCCTGGATATCAGACTCTCCTATAATGATGTTCAGCTGTTTCTTGCCATTGCAAAATCCATCCCAGAGCAAGC
TAATGCTGCAGTGCCAGACTCAGTGGCCCTGGAGTCAGACTCCGTTGGCACTTACCTTCCAGGTGCATCTCGCGTTGGAGAGGAAATCAG
AGAAGGGACAAGACACACCTTAGATCCTGTCTTGGAGTTACAGCTGGCTAGGCTGCAGGAGCTGGGATTCAGCATGGATGATTGTCGCAA
AGCTCTTTTGGCGTGTCAAGGCCAATTGAAAAAGGCAGCAAGTTGGTTGTTTAAGAATGCGGAACCTCTGAAGTCTCTTTCCTTGGCCTC
CACCAGCCGAGATAGCCCAGGGGCTGTGGCAGCGCCATTGATCTCTGGCGTGGAGATCAAAGCTGAGAGTGTGTGCATCTGTTTCATCGA
TGACTGCATGGATTGTGATGTTCCTCTCGCTGAACTCACCTTTTCCCGTCTGAATTTTCTTCAGCGTGTAAGAACTAGCCCTGAAGGCTA
TGCCCACTTCACCCTTTCTGGAGATTATTATAACCGTGCTCTTTCAGGCTGGGAGCCATTTATTGAGCCTTGGCCATGCTCTGTATCCTG
GCAACAGCAGGCAGCTAGTCGTCTCCATCCTCCTCGACTGAAGCTAGAAGCCAAGGCCAAACCTCGTTTGGATATCAATATCACTTCTGT
GCTAATTGACCAGTATGTAAGTACCAAGGAATCGTGGATGGCAGATTACTGTAAAGATGACAAGGACATAGAGTCAGCTAAATCAGAAGA
CTGGATGGGCTCTTCGGTGGATCCTCCATGTTTTGGACAAACAGAGGTGAAAACCCCCAAGCGCCGGCAGCCATTTGTCCCCTTTGCTCT
GAGGAACCACACGGGGTGCACTTTGTGGTTTGCCACCCTGACCACCACACCCACCAGAGCTGCACTCTCTCACAGTGGGAGTCCAGGGGT
AGTTCCAGAAGGGAACGGAACATTTCTCGATGATACTCACAATGTTAGTGAATGGCGAGAAGTCCTTACAGGTGAAGAGATTCCCTTTGA
ATTTGAAGCAAGAGGAAAGTTAAGACACAGACACACCCATGACCTCCGGATTCATCAACTGCAAGTGAGAGTAAATGGCTGGGAGCAAGT
GAGCCCAGTGTCTGTGGACAAAGTCGGGACCTTTTTTCGATATGCAGCACCAGATAAAAATTCATCTTCCTCTACGATTGGCAGCCCAAG
CAGCAGAACAAATATTATACATCCCCAGGTTTATTTCTCTTCACTCCCACCAGTGCGGGTGGTCTTTGCAGTGACTATGGAAGGCAGTGC
ACGGAAAGTCATCACTGTCCGGTCAGCCCTCATTGTGAGGAACAGACTTGAGACACCAATGGAACTAAGACTGGATAGCCCATCAGCTCC
AGACAAGCCAGTGGTGCTTCCTGCTATCATGCCAGGGGATTCGTTTGCTGTGCCTTTACACCTCACTTCTTGGCGGCTACAGGCCCGGCC
CAAAGGATTGGGTGTATTTTTCTGTAAGGCTCCCATTCATTGGACCAATGTAGTGAAGACTGCAGAAATTAGTAGCAGTAAACGAGAGTG
CCACTCTATGGACACAGAAAAAAGCCGATTTTTCAGGTTTTGTGTGGCTATAAAGAAAGAGAATTATCCAGATTATATGCCCTCAAACAT
ATTTTCTGACAGTGCAAAACAGATTTTCAGACAGCCTGGGCATACCATATATCTCCTGCCAACTGTGGTAATCTGCAACTTGCTACCCTG
TGAACTTGATTTTTATGTTAAAGGAATGCCAATTAATGGGACGCTGAAACCTGGCAAGGAGGCAGCTCTCCATACAGCTGATACATCCCA
GAACATTGAGCTGGGGGTATCACTGGAGAATTTCCCCCTCTGTAAAGAATTGCTCATTCCACCTGGAACCCAAAACTATATGGTGAGAAT
GCGACTCTATGACGTCAACCGTCGGCAGCTGAACCTCACCATCCGGATTGTGTGTCGAGCAGAAGGATCCTTAAAGATCTTCATTTCTGC
TCCATATTGGCTGATTAACAAAACAGGGTTGCCACTGATCTTCAGACAGGACAATGCCAAGACAGATGCTGCAGGCCAGTTTGAGGAGCA
TGAGCTGGCCCGTAGCCTGAGTCCTCTCTTATTCTGCTATGCTGACAAAGAGCAGCCAAACCTCTGCACGATGAGAATCGGAAGGGGGAT
TCATCCAGAAGGCATGCCGGGCTGGTGTCAGGGCTTCTCCCTGGATGGTGGTAGTGGTGTCCGAGCTTTGAAAGTCATCCAGCAAGGAAA
CCGCCCAGGGCTGATCTATAACATTGGTATTGATGTCAAGAAAGGCCGAGGTCGATACATTGATACCTGCATGGTCATCTTTGCCCCCCG
TTACCTGTTAGATAATAAATCATCTCACAAGCTTGCATTTGCACAGAGGGAATTTGCCAGGGGACAGGGAACAGCCAATCCCGAAGGTTA
CATTTCCACCCTTCCTGGTTCCAGTGTGGTGTTCCACTGGCCTCGGAATGACTATGATCAGCTATTGTGTGTCAGACTGATGGACGTTCC
CAATTGTATTTGGTCTGGAGGCTTTGAAGTCAACAAGAATAATTCCTTCCATATCAACATGAGGGATACCTTGGGAAAATGCTTCTTCCT
ACGAGTGGAAATTACTCTCCGAGGAGCTACGTATAGGATCTCATTTAGTGACACAGATCAGTTACCTCCTCCTTTCCGAATTGACAACTT
TTCTAAGGTCCCGGTTGTCTTTACTCAGCATGGCGTAGCTGAACCCAGGCTCCGGACTGAAGTGAAGCCCATGACTTCATTGGATTATGC
CTGGGACGAACCCACCTTGCCACCTTTTATCACTCTGACTGTTAAAGGGGCAGGGTCCTCTGAGATCAACTGCAACATGAATGATTTCCA
GGATAATCGGCAGCTTTATTATGAAAATTTCATTTACATTGCTGCTACATATACATTCTCTGGCTTGCAGGAGGGAACAGGCAGGCCTGT
GGCTTCCAACAAGGCCATTACCTGTGCGGAGCTCGTTTTGGATGTCTCACCCAAGACACAAAGAGTCATTTTAAAAAAGAAGGAACCAGG
AAAGCGTTCTCAGCTGTGGAGGATGACAGGAACAGGAATGCTGGCCCATGAGGGCTCCTCAGTTCCTCACAATCCCAATAAGCCCTCAGC
CGCCCGCTCCACCGAGGGGTCTGCCATCTTAGATATTGCTGGTCTCGCTGCAGTGACTGACAACAGATACGAGCCACTGATGCTGAGAAA
GCCTGACCGCAGGCGAAGCACAACTCAGACGTGGAGTTTCCGAGAAGGAAAACTGACCTGTGGGTTACATGGGTTGGTCGTCCAGGCCAA
AGGAGGACTTTCTGGTTTGTTTGATGGAGCTGAAGTTGTTCTTGGTCCTGACACTTCCATGGAGCTTTTGGGGCCAGTTCCACCTGAACA
ACAATTTATTAATCAAAAAATGAGACCTGGTTCTGGAATGTTATCCATCAGAGTCATCCCAGATGGACCAACTAGAGCACTCCAGATAAC
AGATTTCTGCCACCGGAAAAGCAGCCGTTCATATGAAGTGGATGAACTTCCTGTCACCGAACAAGAGCTGCAGAAATTAAAGAATCCAGA
TACAGAGCAGGAATTGGAAGTGCTTGTGAGGTTAGAAGGTGGAATTGGGTTGTCCTTAATTAATAAAGTCCCAGAAGAACTGGTCTTTGC
AAGTCTTACAGGAATCAATGTGCACTATACACAGCTGGCAACCAGTCACATGCTTGAACTCAGCATACAGGATGTACAGGTGGACAATCA
GCTCATTGGTACCACGCAGCCCTTCATGCTCTATGTGACTCCCCTGAGCAATGAGAATGAGGTCATCGAGACCGGCCCAGCTGTGCAAGT
CAACGCAGTGAAGTTCCCCAGTAAGAGTGCACTGACCAACATCTACAAGCATCTGATGATCACAGCTCAGAGATTCACAGTGCAAATTGA
GGAGAAACTGCTCCTCAAGCTGCTAAGTTTCTTTGGCTACGATCAAGCAGAATCAGAGGTGGAAAAATATGATGAAAACCTCCATGAAAA
GACAGCTGAGCAAGGTGGAACACCAATTCGATACTACTTTGAAAATCTCAAAATCAGCATTCCTCAGATCAAGCTAAGTGTGTTCACCTC
CAACAAGCTCCCATTGGATCTTAAGGCCCTAAAAAGCACCTTGGGGTTTCCTTTGATACGGTTTGAAGACGCTGTGATTAATCTAGATCC
ATTCACTCGGGTACATCCCTATGAGACCAAGGAGTTCATCATCAATGATATCCTCAAACATTTCCAGGAGTTTCTTGGCAATCCTATGGG
GCTTTTGAATGATGTTTCTGAAGGGGTTACTGGACTGATAAAATATGGAAATGTCGGGGGCCTCATCAGAAATGTTACACACGGAGTATC
AAACTCTGCTGCCAAGCAAGAAAAACGGATATTTACAAACTTCCATCGCCAGCTTTTTTGTTGGATTGACAAGTGGATCGATCTCACGAT
GGAAGACATTAGGAGAATGGAAGACGAGACTCAGAAAGAACTAGAAACATTACGTAATCAAGGTCAAGTGAGGGGAACAAGCGCAGCCAG
TGATGAGTGAAGAAGAATCTGACCAGTATCTTGCAGTGTTGACGTTTCCCAGATGTGTGCTTGTGATGATACACACACATGCACAGGTTC
TCAACCACGTGTGTATATATGTATGTGTGCATATGTCTGTAGCTGTATATAAAGCGCATGTAGAGCTACAGATCCAGATACACACACTTG
TGTATATATGTACATACAGACATACTGAAGGGATTAGTACAATTTCTCCAAAGTACTGTACCTATCTTCAGCAAGAATGCAAAAGAAAAT
ATTTTCAATATATATACCTGGAACAGATTTTAATAATTATCAGAGTAATACCATTAATGGACAAATTGACTGCAATGTAATACTAGCTGG
TATGTTTCATAAATGTCAAGCTGTGGACCAACATATATAGCCTTTTATTATTTTTCTCTTCTTTTAAGTCAGTCTGTTATAAATTTTTTT
TTAGTCCCATAAGCAGTAGACTCCCACAGAAAATTTCTTCAAAATTTTTTGGTGTTCCAATGAATCTGGGATGTAAACTCTGAATGTATT
TATAACTATTTATTTCTGGATGGTCATTATCTTGTAGCCAAATTTGACAATATAAAGTAAGGAGCAAAGTTACAGGCCAGTTTTTACTTG
TTTGCCCTGAGGGAAAAATCCTTTTAAAAAAAATTTCTGGTTTTTATTGGATTTTTGTATTTTAAATTTCAAATATTTTTCTACATCAAA
CCTAGCAAAAATGGAGATGACGGTTTCTGATTTATAATAAATACTAGACAGTTTTCAGGCTCCTGTTAGACAAACACATTGATGAAGAAA
TTAGTCTTAATAGGATTGTAGGCTGTGTAGAAAAGTTGGAAATATAGCACTTCATGGAGTCTTGTTTTGAAGATGACAGTTTTCTGTAAC
TACAGCTTGGAAACTATGCAAATGGTCTAGATTCCTCAGAGCTCACATGATAGGATATAGTTAGTGATGACATTTTGCTCTTCTTGTGGG
AACACACACTTCAAGGAGGAGATAGTGACTTTGAGATAGGAACAGTTTAAGATGCAGTGTGAGTCTGGCCTGCGTGCGGTGAGGAGGCCC
CGCCAAGAGACTGGTGGACATCTGACTGTGGGATGTGCTCTCAAGTAGGACGTCATCAGGACAGATTCTGAATAGGCATCATGAGAGTGC
TGGTCAGAAACGGCTGCCACTTTTTTTAATTTAATTTTATTTTTTATTTAAAGGAAGGAACAATAGCTAGGTAAGATTTTTATCAGCTTT
CTCTGTCTGAATCCAGTTTTTCCTCTGTCAGTCCTGGAAGCTTGAATAGAATTATATTGTTGAAGCCTTCAGGTCACAAACTGTCTTTTG
TAACCTCCTGTCCCTCCTAAAACACGCCAACCCCTGCAGTCAAATCACATTAGTAATCTGATTTGCTGACAGTCCTGCCCTGCCTGCTCC
TCGTTTTCCCACATGTCCTGCATCCCTCCCCCACTGGAGTGATTTCAGTGAATCAGACAAGGAAGGATGTGTAGGATCACTACTGCATTG
CAATACCCTGTTATCCTCAGCAACAAAACCCACATTTCATACATCCTTTGTGTACTCAGGATAAAGACTGATGTTTACTCTCTGGGCACT
GTTGTAAGATAGGTTTTGTCAGAGCATAATCATTGTCTGCAAAGTGTTTGGTGCGAGGAAGATTATTGCTAATTTTGTGAAATAAAGAGT
CTAGCCCTCTCCTTTTAATGAACTTAACTCTCGCTGGCATCTGTAGTATCATTGGGAGCTTAGGCGCACATGGAAATGAGAGCCCGGCGC
ATGGATTTTAATGTTTTTCTAACAACTGTGGAGATTTGAGGGAATGTGTGGTGAATGTAAAATACCTAGTTTACTTGCCAGTCTCTTGTG

>98331_98331_1_VPS13D-PITPNB_VPS13D_chr1_12476754_ENST00000356315_PITPNB_chr22_28254502_ENST00000320996_length(amino acids)=4129AA_BP=4071
MLEGLVAWVLNTYLGKYVNNLNTDQLSVALLKGAVELENLPLKKDALKELELPFEVKAGFIGKVTLQIPFYRPHVDPWVISISSLHLIGA
PEKIQDFNDEKEKLLERERKKALLQALEEKWKNDRQQKGESYWYSVTASVVTRIVENIELKIQDVHLRFEDGVTNPSHPFAFGICIKNVS
MQNAVNEPVQKLMRKKQLDVAEFSIYWDVDCTLLGDLPQMELQEAMARSMESRSHHYVLEPVFASALLKRNCSKKPLRSRHSPRIDCDIQ
LETIPLKLSQLQYRQIMEFLKELERKERQVKFRRWKPKVAISKNCREWWYFALNANLYEIREQRKRCTWDFMLHRARDAVSYTDKYFNKL
KGGLLSTDDKEEMCRIEEEQSFEELKILRELVHDRFHKQEELAESLREPQFDSPGACPGAPEPGGGSGMLQYLQSWFPGWGGWYGQQTPE
GNVVEGLSAEQQEQWIPEEILGTEEFFDPTADASCMNTYTKRDHVFAKLNLQLQRGTVTLLHKEQGTPQMNESAFMQLEFSDVKLLAESL
PRRNSSLLSVRLGGLFLRDLATEGTMFPLLVFPNPQKEVGRVSQSFGLQTTSADRSDHYPAADPDGPVFEMLYERNPAHSHFERRLNVST
RPLNIIYNPQAIKKVADFFYKGKVHTSGFGYQSELELRVAEAARRQYNKLKMQTKAEIRQTLDRLLVGDFIEESKRWTVRLDISAPQVIF
PDDFKFKNPVLVVVDLGRMLLTNTQDNSRRKSRDGSASEETQFSDDEYKTPLATPPNTPPPESSSSNGEKTPPFSGVEFSEEQLQAHLMS
TKMYERYSLSFMDLQIMVGRVKDNWKHVQDIDVGPTHVVEKFNVHLQLERRLIYTSDPKYPGAVLSGNLPDLKIHINEDKISALKNCFAL
LTTPEMKTSDTQIKEKIFPQEEQRGSLQDSVMNLTQSIVLLEQHTREVLVESQLLLAEFKVNCMQLGVESNGRYISVLKVFGTNAHFVKR
PYDAEVSLTVHGLLLVDTMQTYGADFDLLMASHKNLSFDIPTGSLRDSRAQSPVSGPNVAHLTDGATLNDRSATSVSLDKILTKEQESLI
KLEYQFVSSECPSMNLDSTLQVISLQVNNLDIILNPETIVELIGFLQKSFPKEKDDLSPQPLMTDFERSFREQGTYQSTYEQNTEVAVEI
HRLNLLLLRTVGMANREKYGRKIATASIGGTKVNVSMGSTFDMNGSLGCLQLMDLTQDNVKNQYVVSIGNSVGYENIISDIGYFESVFVR
MEDAALTEALSFTFVERSKQECFLNLKMASLHYNHSAKFLKELTLSMDELEENFRGMLKSAATKVTTVLATKTAEYSEMVSLFETPRKTR
EPFILEENEIYGFDLASSHLDTVKLILNINIESPVVSIPRKPGSPELLVGHLGQIFIQNFVAGDDESRSDRLQVEIKDIKLYSLNCTQLA
GREAVGSEGSRMFCPPSGSGSANSQEEAHFTRHDFFESLHRGQAFHILNNTTIQFKLEKIPIERESELTFSLSPDDLGTSSIMKIEGKFV
NPVQVVLAKHVYEQVLQTLDNLVYSEDLNKYPASATSSPCPDSPLPPLSTCGESSVERKENGLFSHSSLSNTSQKSLSVKEVKSFTQIQA
TFCISELQVQLSGDLTLGAQGLVSLKFQDFEVEFSKDHPQTLSIQIALHSLLMEDLLEKNPDSKYKNLMVSRGAPKPSSLAQKEYLSQSC
PSVSNVEYPDMPRSLPSHMEEAPNVFQLYQRPTSASRKKQKEVQDKDYPLTPPPSPTVDEPKILVGKSKFDDSLVHINIFLVDKKHPEFS
SSYNRVNRSIDVDFNCLDVLITLQTWVVILDFFGIGSTADNHAMRLPPEGILHNVKLEPHASMESGLQDPVNTKLDLKVHSLSLVLNKTT
SELAKANVSKLVAHLEMIEGDLALQGSIGSLSLSDLTCHGEFYRERFTTSGEEALIFQTFKYGRPDPLLRREHDIRVSLRMASVQYVHTQ
RFQAEVVAFIQHFTQLQDVLGRQRAAIEGQTVRDQAQRCSRVLLDIEAGAPVLLIPESSRSNNLIVANLGKLKVKNKFLFAGFPGTFSLQ
DKESVPSASPTGIPKHSLRKTTSTEEPRGTHSQGQFTMPLAGMSLGSLKSEFVPSTSTKQQGPQPTLSVGQESSSPEDHVCLLDCVVVDL
QDMDIFAAERHPREYSKAPEDSSGDLIFPSYFVRQTGGSLLTEPCRLKLQVERNLDKEISHTVPDISIHGNLSSVHCSLDLYKYKLIRGL
LENNLGEPIEEFMRPYDLQDPRIHTVLSGEVYTCMCFLIDMVNVSLELKDPKRKEGAGSLARFDFKKCKLLYESFSNQTKSINLVSHSMM
AFDTRYAGQKTSPGMTNVFSCIFQPAKNSSTTQGSIQIELHFRSTKDSSCFTVVLNNLRVFLIFDWLLLVHDFLHTPSDIKKQNHVTPSR
HRNSSSESAIVPKTVKSGVVTKRSSLPVSNERHLEVKVNVTGTEFVVIEDVSCFDTNAIILKGTTVLTYKPRFVDRPFSGSLFGIEVFSC
RLGNEHDTALSIVDPVQIQMELVGNSSYQNSSGLMDAFNSEDFPPVLEIQLQALDIRLSYNDVQLFLAIAKSIPEQANAAVPDSVALESD
SVGTYLPGASRVGEEIREGTRHTLDPVLELQLARLQELGFSMDDCRKALLACQGQLKKAASWLFKNAEPLKSLSLASTSRDSPGAVAAPL
ISGVEIKAESVCICFIDDCMDCDVPLAELTFSRLNFLQRVRTSPEGYAHFTLSGDYYNRALSGWEPFIEPWPCSVSWQQQAASRLHPPRL
KLEAKAKPRLDINITSVLIDQYVSTKESWMADYCKDDKDIESAKSEDWMGSSVDPPCFGQTEVKTPKRRQPFVPFALRNHTGCTLWFATL
TTTPTRAALSHSGSPGVVPEGNGTFLDDTHNVSEWREVLTGEEIPFEFEARGKLRHRHTHDLRIHQLQVRVNGWEQVSPVSVDKVGTFFR
YAAPDKNSSSSTIGSPSSRTNIIHPQVYFSSLPPVRVVFAVTMEGSARKVITVRSALIVRNRLETPMELRLDSPSAPDKPVVLPAIMPGD
SFAVPLHLTSWRLQARPKGLGVFFCKAPIHWTNVVKTAEISSSKRECHSMDTEKSRFFRFCVAIKKENYPDYMPSNIFSDSAKQIFRQPG
HTIYLLPTVVICNLLPCELDFYVKGMPINGTLKPGKEAALHTADTSQNIELGVSLENFPLCKELLIPPGTQNYMVRMRLYDVNRRQLNLT
IRIVCRAEGSLKIFISAPYWLINKTGLPLIFRQDNAKTDAAGQFEEHELARSLSPLLFCYADKEQPNLCTMRIGRGIHPEGMPGWCQGFS
LDGGSGVRALKVIQQGNRPGLIYNIGIDVKKGRGRYIDTCMVIFAPRYLLDNKSSHKLAFAQREFARGQGTANPEGYISTLPGSSVVFHW
PRNDYDQLLCVRLMDVPNCIWSGGFEVNKNNSFHINMRDTLGKCFFLRVEITLRGATYRISFSDTDQLPPPFRIDNFSKVPVVFTQHGVA
EPRLRTEVKPMTSLDYAWDEPTLPPFITLTVKGAGSSEINCNMNDFQDNRQLYYENFIYIAATYTFSGLQEGTGRPVASNKAITCAELVL
DVSPKTQRVILKKKEPGKRSQLWRMTGTGMLAHEGSSVPHNPNKPSAARSTEGSAILDIAGLAAVTDNRYEPLMLRKPDRRRSTTQTWSF
REGKLTCGLHGLVVQAKGGLSGLFDGAEVVLGPDTSMELLGPVPPEQQFINQKMRPGSGMLSIRVIPDGPTRALQITDFCHRKSSRSYEV
DELPVTEQELQKLKNPDTEQELEVLVRLEGGIGLSLINKVPEELVFASLTGINVHYTQLATSHMLELSIQDVQVDNQLIGTTQPFMLYVT
PLSNENEVIETGPAVQVNAVKFPSKSALTNIYKHLMITAQRFTVQIEEKLLLKLLSFFGYDQAESEVEKYDENLHEKTAEQGGTPIRYYF
ENLKISIPQIKLSVFTSNKLPLDLKALKSTLGFPLIRFEDAVINLDPFTRVHPYETKEFIINDILKHFQEFLGNPMGLLNDVSEGVTGLI

--------------------------------------------------------------
>98331_98331_2_VPS13D-PITPNB_VPS13D_chr1_12476754_ENST00000356315_PITPNB_chr22_28254502_ENST00000335272_length(transcript)=14550nt_BP=12346nt
GGAGGAAACGCCGCGCAGCGCCGGGCTGGGGCGGGCGGCCCGGGACACCGACAGATTTTTCTGTGACCATGAAAGAGAGAAATAAAGAAT
GATCCATGATTTCTAAACACCTTTTCCTGAGGATATAGTCATGTTGGAAGGCCTTGTAGCCTGGGTTCTCAATACCTATTTGGGAAAATA
TGTCAATAACCTGAACACTGACCAGCTCTCAGTTGCACTTCTCAAAGGTGCTGTTGAATTAGAAAACTTGCCATTAAAGAAAGATGCCTT
GAAAGAATTGGAATTACCATTTGAAGTCAAAGCTGGCTTCATTGGGAAAGTAACCCTTCAGATTCCCTTTTATCGCCCCCATGTGGACCC
TTGGGTGATCTCCATCTCCAGCCTTCACTTAATTGGAGCCCCAGAGAAAATACAGGATTTCAATGATGAAAAGGAGAAGCTGTTGGAAAG
GGAACGTAAGAAAGCACTACTTCAAGCCCTGGAGGAGAAATGGAAGAATGACCGCCAGCAGAAAGGGGAGTCCTATTGGTATTCAGTTAC
CGCCTCCGTAGTTACAAGGATTGTGGAGAATATTGAATTAAAAATTCAAGATGTCCATTTACGCTTTGAAGATGGTGTCACCAATCCCTC
CCATCCTTTTGCTTTTGGCATCTGCATTAAGAATGTGTCCATGCAAAATGCTGTGAATGAGCCTGTACAGAAACTAATGCGGAAAAAGCA
ATTAGACGTAGCAGAATTTAGCATCTATTGGGATGTCGATTGCACTTTACTGGGGGATTTGCCTCAGATGGAGTTACAGGAGGCCATGGC
CAGGAGCATGGAGAGTCGCAGCCATCACTACGTCCTGGAGCCTGTGTTTGCATCTGCTCTTTTGAAGAGAAACTGCTCCAAGAAGCCCCT
GCGGTCTCGGCACAGTCCCCGTATTGATTGTGATATTCAGCTGGAGACCATTCCCTTGAAACTCTCTCAGCTGCAATACCGGCAAATCAT
GGAATTCCTCAAGGAGCTGGAACGAAAGGAGAGGCAGGTGAAGTTCCGAAGGTGGAAACCCAAGGTGGCGATATCTAAGAACTGCCGAGA
ATGGTGGTATTTTGCTTTGAATGCTAACTTGTATGAGATCAGAGAGCAGAGGAAACGTTGCACCTGGGACTTTATGTTGCACCGCGCTCG
TGATGCTGTATCTTACACTGACAAATATTTCAACAAGTTAAAAGGAGGCCTGCTGTCCACAGATGACAAGGAGGAAATGTGTCGGATTGA
AGAGGAACAGAGCTTTGAGGAATTGAAGATTTTGCGTGAACTGGTTCATGATCGATTTCACAAACAGGAAGAACTAGCAGAGAGTCTGCG
GGAGCCTCAGTTTGATTCTCCAGGAGCCTGTCCGGGAGCCCCAGAACCCGGTGGAGGCAGTGGGATGCTGCAGTATCTCCAGTCCTGGTT
TCCTGGATGGGGTGGCTGGTACGGGCAGCAGACCCCAGAAGGGAATGTGGTTGAGGGACTGTCAGCAGAGCAACAGGAGCAGTGGATTCC
TGAAGAGATCCTGGGCACTGAGGAGTTTTTTGACCCCACTGCAGATGCCTCGTGTATGAACACGTATACAAAGCGAGATCATGTCTTTGC
CAAACTGAATTTGCAGTTGCAGCGAGGTACAGTGACTCTGTTACACAAGGAGCAAGGAACTCCTCAAATGAATGAAAGTGCTTTCATGCA
GCTCGAGTTTTCAGATGTAAAACTTCTAGCAGAGTCTCTTCCTCGAAGAAATTCCTCGTTGCTTTCAGTCCGGTTGGGTGGACTGTTTCT
TCGAGACCTGGCTACAGAAGGAACTATGTTTCCTCTTCTAGTCTTCCCTAATCCACAAAAAGAAGTTGGCAGAGTCTCACAATCTTTTGG
TCTACAAACTACATCTGCAGACAGAAGTGATCATTACCCAGCTGCAGATCCAGATGGCCCCGTTTTTGAGATGCTGTATGAGAGAAATCC
GGCGCACAGCCACTTTGAGAGGCGGCTCAATGTCAGCACAAGGCCCTTGAACATCATATACAATCCGCAGGCCATTAAAAAAGTAGCAGA
CTTTTTCTACAAGGGAAAGGTTCATACCTCAGGTTTTGGTTATCAGTCTGAACTTGAGCTGAGAGTGGCTGAAGCTGCCCGAAGACAATA
TAACAAGCTGAAGATGCAGACCAAGGCAGAAATCCGGCAAACTCTTGATCGTTTGCTAGTGGGTGATTTCATTGAGGAGAGTAAACGATG
GACCGTGCGGCTGGATATTTCTGCCCCTCAGGTGATATTTCCTGATGATTTCAAATTCAAGAATCCTGTGTTAGTTGTCGTGGATCTAGG
AAGAATGCTTTTGACGAACACCCAAGATAACTCCAGGAGGAAAAGTAGGGATGGGTCAGCATCTGAAGAGACCCAGTTTAGTGATGATGA
ATATAAGACCCCCCTGGCCACACCTCCTAACACCCCACCTCCCGAGTCAAGCAGCAGCAACGGAGAGAAAACACCTCCCTTTTCTGGAGT
TGAGTTCAGTGAAGAACAGCTTCAAGCACATTTAATGAGCACAAAGATGTATGAGAGGTACTCGCTGTCATTTATGGACCTCCAGATCAT
GGTTGGACGAGTGAAAGACAATTGGAAGCATGTCCAGGATATTGACGTGGGACCAACACATGTGGTAGAGAAGTTCAACGTTCACCTACA
GTTAGAGCGTCGATTGATTTATACTTCAGATCCCAAATATCCAGGAGCCGTGCTCTCAGGCAACTTACCAGACTTAAAAATCCACATTAA
TGAAGATAAAATATCTGCACTAAAGAATTGCTTTGCTCTCCTCACCACCCCAGAAATGAAAACTTCTGACACTCAGATTAAAGAAAAGAT
TTTTCCCCAGGAGGAGCAGCGGGGAAGTTTGCAAGACTCCGTAATGAATTTAACCCAGAGCATTGTGTTGTTGGAGCAGCATACCCGCGA
GGTTCTGGTGGAGTCGCAGCTCCTCCTGGCGGAATTTAAAGTGAACTGTATGCAGCTTGGTGTTGAGAGCAATGGCCGGTACATTTCTGT
GCTCAAGGTGTTTGGTACCAATGCTCACTTTGTGAAGAGGCCTTATGATGCTGAAGTCTCCCTAACTGTTCATGGTTTGCTCCTGGTGGA
TACCATGCAGACATATGGTGCTGATTTTGACCTTTTGATGGCTTCACATAAGAACTTGAGCTTTGATATTCCAACGGGAAGCCTTCGGGA
TAGCAGGGCCCAGTCTCCTGTCTCTGGACCGAATGTGGCCCACTTAACTGATGGAGCTACACTGAACGACCGATCAGCTACTAGTGTTTC
ACTTGACAAAATTCTTACCAAAGAGCAAGAGTCCCTTATTAAGTTGGAATATCAGTTTGTGAGTTCAGAGTGCCCATCGATGAATTTAGA
CAGTACTCTTCAGGTGATTTCCCTACAGGTGAATAATTTAGATATTATCCTCAATCCAGAGACGATTGTGGAGCTAATTGGTTTTCTTCA
AAAATCCTTTCCCAAGGAAAAAGATGATTTAAGTCCTCAACCTTTAATGACTGATTTTGAAAGAAGCTTCAGAGAACAAGGAACTTACCA
GTCTACATATGAACAAAACACTGAGGTTGCAGTGGAAATCCATAGGCTGAACTTACTGCTTCTTCGGACAGTGGGCATGGCAAATAGAGA
GAAATATGGCAGAAAAATTGCAACTGCAAGTATAGGTGGCACCAAAGTTAATGTCTCAATGGGTAGCACGTTTGACATGAATGGTTCTCT
TGGCTGTTTACAGCTTATGGATTTGACACAAGATAACGTTAAAAACCAGTATGTTGTCAGCATTGGGAATTCTGTAGGCTATGAAAATAT
CATCAGTGATATTGGCTACTTTGAATCTGTGTTTGTCAGAATGGAAGATGCAGCCCTCACTGAAGCTTTGAGTTTCACGTTTGTTGAGAG
ATCTAAACAGGAGTGTTTTCTCAACCTGAAGATGGCTTCTTTACATTATAACCACTCTGCTAAGTTTTTGAAGGAGTTGACGTTATCCAT
GGATGAACTGGAAGAAAATTTTCGAGGTATGCTGAAAAGCGCAGCCACCAAAGTCACCACAGTACTAGCTACCAAGACTGCCGAGTATAG
CGAGATGGTATCGCTCTTTGAAACTCCAAGGAAGACTCGGGAACCCTTTATCTTAGAGGAAAATGAAATATATGGGTTTGACCTAGCTTC
GTCTCATTTGGACACTGTAAAGCTAATCTTGAACATAAACATTGAATCACCAGTTGTTTCTATCCCTCGGAAGCCGGGGAGTCCTGAGTT
GTTGGTGGGACACTTGGGACAGATATTCATCCAGAATTTTGTGGCGGGAGATGATGAATCCAGAAGTGACCGTCTGCAGGTGGAAATCAA
GGACATTAAACTGTATTCTTTGAATTGCACCCAGTTGGCAGGTAGAGAAGCTGTTGGGTCTGAAGGAAGCCGGATGTTTTGCCCACCTTC
CGGGTCTGGCAGTGCCAACAGTCAGGAGGAAGCTCATTTCACACGACATGATTTCTTTGAATCTTTGCATAGAGGTCAAGCTTTTCACAT
CCTGAACAACACCACCATTCAGTTTAAACTGGAGAAGATCCCTATAGAGAGAGAATCTGAATTGACTTTTTCTCTTAGCCCAGATGACCT
GGGAACTTCTAGCATCATGAAGATTGAAGGAAAATTTGTCAATCCAGTTCAGGTGGTGTTAGCAAAGCATGTATATGAGCAGGTTTTACA
AACCCTGGACAATCTCGTGTACAGTGAAGATCTGAATAAGTATCCAGCCAGTGCTACCTCCTCCCCTTGCCCTGATTCTCCTCTGCCTCC
CCTCAGTACCTGTGGAGAATCTTCTGTTGAAAGGAAGGAGAATGGATTGTTCAGCCACTCCAGCCTTTCTAACACCTCTCAGAAGTCATT
GTCAGTGAAGGAAGTCAAATCCTTTACTCAGATTCAAGCCACCTTTTGTATATCAGAGCTTCAGGTTCAGCTAAGTGGAGATCTGACTTT
GGGGGCCCAAGGTCTTGTGAGCTTAAAGTTTCAGGACTTTGAGGTGGAATTCAGTAAAGACCATCCCCAGACTTTATCTATTCAGATTGC
CCTGCATTCTCTGCTGATGGAGGACTTATTGGAGAAGAATCCAGATTCTAAATATAAGAACCTGATGGTGTCTCGAGGAGCCCCTAAGCC
ATCTAGTTTAGCACAAAAAGAATACCTTTCTCAGTCTTGCCCCTCAGTGTCCAATGTGGAATATCCTGATATGCCTCGGTCTCTCCCTTC
CCACATGGAAGAAGCTCCTAATGTCTTCCAGTTGTATCAAAGGCCCACCTCTGCGTCCCGGAAAAAGCAAAAGGAAGTCCAAGACAAGGA
CTATCCCTTGACCCCACCTCCTTCTCCAACAGTGGATGAGCCCAAGATACTTGTTGGAAAGAGTAAATTTGATGATTCCTTAGTCCACAT
CAACATATTCTTGGTAGATAAGAAACATCCAGAATTCTCTTCCAGTTACAATCGAGTTAACCGGAGCATTGATGTTGATTTTAATTGCTT
GGATGTGCTGATCACACTGCAAACCTGGGTTGTGATATTAGACTTTTTTGGAATCGGCTCCACTGCAGACAACCACGCAATGAGGCTGCC
TCCTGAGGGCATTCTGCACAACGTGAAGTTGGAGCCACATGCCTCCATGGAGTCTGGACTTCAGGATCCAGTGAACACCAAACTGGATCT
CAAGGTTCATTCACTTTCTCTAGTGCTGAATAAGACCACCAGTGAGCTTGCCAAAGCAAATGTGTCCAAATTAGTAGCACACCTGGAAAT
GATTGAGGGAGACCTGGCCTTACAGGGCAGCATTGGGAGTCTGTCTCTAAGTGACCTCACATGCCATGGAGAGTTCTACAGAGAACGGTT
CACTACCAGTGGTGAAGAAGCACTCATCTTCCAGACTTTTAAATACGGACGGCCTGACCCTCTGCTCCGGAGAGAACACGACATTCGCGT
GAGCCTCCGGATGGCCTCTGTGCAGTATGTGCATACTCAGCGTTTCCAGGCAGAGGTGGTGGCCTTCATTCAGCATTTCACTCAGCTGCA
GGATGTCTTAGGGCGCCAGCGAGCTGCTATTGAGGGGCAGACGGTGAGAGATCAAGCCCAGCGCTGTTCACGGGTTCTCCTGGATATTGA
GGCTGGTGCTCCCGTTCTCTTGATCCCAGAAAGTTCCAGATCAAATAATCTGATTGTAGCAAATTTGGGGAAGTTGAAAGTCAAAAATAA
GTTTCTGTTTGCTGGTTTTCCTGGCACCTTTTCCCTACAAGATAAGGAATCTGTGCCTTCAGCTTCCCCAACGGGTATTCCCAAACACAG
TCTGAGGAAAACGACAAGCACGGAGGAGCCCAGGGGAACCCATTCCCAGGGGCAGTTCACGATGCCTCTTGCTGGAATGAGCCTAGGAAG
CCTGAAGAGTGAGTTTGTGCCCAGTACCTCCACCAAGCAGCAAGGGCCGCAACCCACACTGTCTGTTGGCCAAGAGTCCAGTAGTCCAGA
AGACCATGTCTGCCTGCTGGATTGCGTTGTCGTGGATCTCCAGGACATGGACATCTTTGCTGCAGAGAGACATCCGAGAGAATACTCGAA
GGCACCAGAGGATAGTAGTGGAGATCTGATCTTCCCTTCCTATTTTGTGCGACAGACAGGAGGAAGCCTCTTAACCGAGCCTTGTAGGCT
GAAATTGCAGGTGGAAAGGAATTTGGACAAAGAAATAAGTCATACTGTGCCAGACATATCTATCCATGGCAATCTCTCCTCAGTCCACTG
CTCTCTGGATCTGTATAAATACAAGCTGATCCGCGGCTTATTAGAGAACAACCTGGGAGAACCCATAGAGGAATTTATGCGGCCTTATGA
TTTACAAGATCCAAGAATTCATACTGTCCTGAGTGGAGAAGTGTACACCTGTATGTGCTTCCTCATTGATATGGTGAATGTAAGTCTGGA
GCTTAAAGATCCAAAAAGAAAAGAAGGTGCTGGGTCCCTAGCCAGATTTGACTTCAAGAAATGCAAACTGCTCTATGAAAGTTTTTCCAA
CCAAACCAAGTCCATTAACTTGGTTTCCCATTCCATGATGGCTTTTGACACCCGTTATGCTGGGCAGAAGACCAGCCCTGGCATGACGAA
TGTGTTCAGCTGTATCTTTCAGCCCGCTAAGAACAGCAGCACCACCCAAGGGTCCATTCAGATTGAACTACATTTCAGATCTACCAAGGA
TTCCTCCTGCTTTACAGTAGTTCTCAACAATCTCCGTGTGTTTCTCATATTTGACTGGCTACTGTTAGTCCATGATTTTCTCCACACTCC
CAGTGATATTAAGAAACAAAATCATGTTACTCCTTCTCGCCACCGTAACTCTAGCAGCGAATCTGCTATAGTTCCCAAAACTGTGAAGAG
TGGAGTAGTTACCAAGCGGTCTTCCCTTCCTGTGTCCAATGAAAGGCACCTGGAGGTCAAGGTCAATGTAACAGGTACGGAGTTTGTGGT
CATTGAAGATGTGTCCTGCTTCGACACCAATGCCATTATTCTGAAAGGCACCACAGTGCTCACCTATAAGCCCCGGTTTGTTGATCGCCC
CTTTTCAGGAAGTTTGTTTGGCATTGAGGTGTTTTCATGCCGACTAGGGAATGAGCATGATACAGCTCTTTCAATTGTGGATCCCGTACA
AATTCAAATGGAGTTGGTGGGGAATTCTTCTTATCAAAATAGTTCAGGATTGATGGATGCATTCAATAGTGAAGATTTCCCACCTGTCCT
GGAGATTCAGTTACAAGCCCTGGATATCAGACTCTCCTATAATGATGTTCAGCTGTTTCTTGCCATTGCAAAATCCATCCCAGAGCAAGC
TAATGCTGCAGTGCCAGACTCAGTGGCCCTGGAGTCAGACTCCGTTGGCACTTACCTTCCAGGTGCATCTCGCGTTGGAGAGGAAATCAG
AGAAGGGACAAGACACACCTTAGATCCTGTCTTGGAGTTACAGCTGGCTAGGCTGCAGGAGCTGGGATTCAGCATGGATGATTGTCGCAA
AGCTCTTTTGGCGTGTCAAGGCCAATTGAAAAAGGCAGCAAGTTGGTTGTTTAAGAATGCGGAACCTCTGAAGTCTCTTTCCTTGGCCTC
CACCAGCCGAGATAGCCCAGGGGCTGTGGCAGCGCCATTGATCTCTGGCGTGGAGATCAAAGCTGAGAGTGTGTGCATCTGTTTCATCGA
TGACTGCATGGATTGTGATGTTCCTCTCGCTGAACTCACCTTTTCCCGTCTGAATTTTCTTCAGCGTGTAAGAACTAGCCCTGAAGGCTA
TGCCCACTTCACCCTTTCTGGAGATTATTATAACCGTGCTCTTTCAGGCTGGGAGCCATTTATTGAGCCTTGGCCATGCTCTGTATCCTG
GCAACAGCAGGCAGCTAGTCGTCTCCATCCTCCTCGACTGAAGCTAGAAGCCAAGGCCAAACCTCGTTTGGATATCAATATCACTTCTGT
GCTAATTGACCAGTATGTAAGTACCAAGGAATCGTGGATGGCAGATTACTGTAAAGATGACAAGGACATAGAGTCAGCTAAATCAGAAGA
CTGGATGGGCTCTTCGGTGGATCCTCCATGTTTTGGACAAACAGAGGTGAAAACCCCCAAGCGCCGGCAGCCATTTGTCCCCTTTGCTCT
GAGGAACCACACGGGGTGCACTTTGTGGTTTGCCACCCTGACCACCACACCCACCAGAGCTGCACTCTCTCACAGTGGGAGTCCAGGGGT
AGTTCCAGAAGGGAACGGAACATTTCTCGATGATACTCACAATGTTAGTGAATGGCGAGAAGTCCTTACAGGTGAAGAGATTCCCTTTGA
ATTTGAAGCAAGAGGAAAGTTAAGACACAGACACACCCATGACCTCCGGATTCATCAACTGCAAGTGAGAGTAAATGGCTGGGAGCAAGT
GAGCCCAGTGTCTGTGGACAAAGTCGGGACCTTTTTTCGATATGCAGCACCAGATAAAAATTCATCTTCCTCTACGATTGGCAGCCCAAG
CAGCAGAACAAATATTATACATCCCCAGGTTTATTTCTCTTCACTCCCACCAGTGCGGGTGGTCTTTGCAGTGACTATGGAAGGCAGTGC
ACGGAAAGTCATCACTGTCCGGTCAGCCCTCATTGTGAGGAACAGACTTGAGACACCAATGGAACTAAGACTGGATAGCCCATCAGCTCC
AGACAAGCCAGTGGTGCTTCCTGCTATCATGCCAGGGGATTCGTTTGCTGTGCCTTTACACCTCACTTCTTGGCGGCTACAGGCCCGGCC
CAAAGGATTGGGTGTATTTTTCTGTAAGGCTCCCATTCATTGGACCAATGTAGTGAAGACTGCAGAAATTAGTAGCAGTAAACGAGAGTG
CCACTCTATGGACACAGAAAAAAGCCGATTTTTCAGGTTTTGTGTGGCTATAAAGAAAGAGAATTATCCAGATTATATGCCCTCAAACAT
ATTTTCTGACAGTGCAAAACAGATTTTCAGACAGCCTGGGCATACCATATATCTCCTGCCAACTGTGGTAATCTGCAACTTGCTACCCTG
TGAACTTGATTTTTATGTTAAAGGAATGCCAATTAATGGGACGCTGAAACCTGGCAAGGAGGCAGCTCTCCATACAGCTGATACATCCCA
GAACATTGAGCTGGGGGTATCACTGGAGAATTTCCCCCTCTGTAAAGAATTGCTCATTCCACCTGGAACCCAAAACTATATGGTGAGAAT
GCGACTCTATGACGTCAACCGTCGGCAGCTGAACCTCACCATCCGGATTGTGTGTCGAGCAGAAGGATCCTTAAAGATCTTCATTTCTGC
TCCATATTGGCTGATTAACAAAACAGGGTTGCCACTGATCTTCAGACAGGACAATGCCAAGACAGATGCTGCAGGCCAGTTTGAGGAGCA
TGAGCTGGCCCGTAGCCTGAGTCCTCTCTTATTCTGCTATGCTGACAAAGAGCAGCCAAACCTCTGCACGATGAGAATCGGAAGGGGGAT
TCATCCAGAAGGCATGCCGGGCTGGTGTCAGGGCTTCTCCCTGGATGGTGGTAGTGGTGTCCGAGCTTTGAAAGTCATCCAGCAAGGAAA
CCGCCCAGGGCTGATCTATAACATTGGTATTGATGTCAAGAAAGGCCGAGGTCGATACATTGATACCTGCATGGTCATCTTTGCCCCCCG
TTACCTGTTAGATAATAAATCATCTCACAAGCTTGCATTTGCACAGAGGGAATTTGCCAGGGGACAGGGAACAGCCAATCCCGAAGGTTA
CATTTCCACCCTTCCTGGTTCCAGTGTGGTGTTCCACTGGCCTCGGAATGACTATGATCAGCTATTGTGTGTCAGACTGATGGACGTTCC
CAATTGTATTTGGTCTGGAGGCTTTGAAGTCAACAAGAATAATTCCTTCCATATCAACATGAGGGATACCTTGGGAAAATGCTTCTTCCT
ACGAGTGGAAATTACTCTCCGAGGAGCTACGTATAGGATCTCATTTAGTGACACAGATCAGTTACCTCCTCCTTTCCGAATTGACAACTT
TTCTAAGGTCCCGGTTGTCTTTACTCAGCATGGCGTAGCTGAACCCAGGCTCCGGACTGAAGTGAAGCCCATGACTTCATTGGATTATGC
CTGGGACGAACCCACCTTGCCACCTTTTATCACTCTGACTGTTAAAGGGGCAGGGTCCTCTGAGATCAACTGCAACATGAATGATTTCCA
GGATAATCGGCAGCTTTATTATGAAAATTTCATTTACATTGCTGCTACATATACATTCTCTGGCTTGCAGGAGGGAACAGGCAGGCCTGT
GGCTTCCAACAAGGCCATTACCTGTGCGGAGCTCGTTTTGGATGTCTCACCCAAGACACAAAGAGTCATTTTAAAAAAGAAGGAACCAGG
AAAGCGTTCTCAGCTGTGGAGGATGACAGGAACAGGAATGCTGGCCCATGAGGGCTCCTCAGTTCCTCACAATCCCAATAAGCCCTCAGC
CGCCCGCTCCACCGAGGGGTCTGCCATCTTAGATATTGCTGGTCTCGCTGCAGTGACTGACAACAGATACGAGCCACTGATGCTGAGAAA
GCCTGACCGCAGGCGAAGCACAACTCAGACGTGGAGTTTCCGAGAAGGAAAACTGACCTGTGGGTTACATGGGTTGGTCGTCCAGGCCAA
AGGAGGACTTTCTGGTTTGTTTGATGGAGCTGAAGTTGTTCTTGGTCCTGACACTTCCATGGAGCTTTTGGGGCCAGTTCCACCTGAACA
ACAATTTATTAATCAAAAAATGAGACCTGGTTCTGGAATGTTATCCATCAGAGTCATCCCAGATGGACCAACTAGAGCACTCCAGATAAC
AGATTTCTGCCACCGGAAAAGCAGCCGTTCATATGAAGTGGATGAACTTCCTGTCACCGAACAAGAGCTGCAGAAATTAAAGAATCCAGA
TACAGAGCAGGAATTGGAAGTGCTTGTGAGGTTAGAAGGTGGAATTGGGTTGTCCTTAATTAATAAAGTCCCAGAAGAACTGGTCTTTGC
AAGTCTTACAGGAATCAATGTGCACTATACACAGCTGGCAACCAGTCACATGCTTGAACTCAGCATACAGGATGTACAGGTGGACAATCA
GCTCATTGGTACCACGCAGCCCTTCATGCTCTATGTGACTCCCCTGAGCAATGAGAATGAGGTCATCGAGACCGGCCCAGCTGTGCAAGT
CAACGCAGTGAAGTTCCCCAGTAAGAGTGCACTGACCAACATCTACAAGCATCTGATGATCACAGCTCAGAGATTCACAGTGCAAATTGA
GGAGAAACTGCTCCTCAAGCTGCTAAGTTTCTTTGGCTACGATCAAGCAGAATCAGAGGTGGAAAAATATGATGAAAACCTCCATGAAAA
GACAGCTGAGCAAGGTGGAACACCAATTCGATACTACTTTGAAAATCTCAAAATCAGCATTCCTCAGATCAAGCTAAGTGTGTTCACCTC
CAACAAGCTCCCATTGGATCTTAAGGCCCTAAAAAGCACCTTGGGGTTTCCTTTGATACGGTTTGAAGACGCTGTGATTAATCTAGATCC
ATTCACTCGGGTACATCCCTATGAGACCAAGGAGTTCATCATCAATGATATCCTCAAACATTTCCAGGAGTTTCTTGGCAATCCTATGGG
GCTTTTGAATGATGTTTCTGAAGGGGTTACTGGACTGATAAAATATGGAAATGTCGGGGGCCTCATCAGAAATGTTACACACGGAGTATC
AAACTCTGCTGCCAAGCAAGAAAAACGGATATTTACAAACTTCCATCGCCAGCTTTTTTGTTGGATTGACAAGTGGATCGATCTCACGAT
GGAAGACATTAGGAGAATGGAAGACGAGACTCAGAAAGAACTAGAAACAATGCGTAAGAGGGGTTCCGTTCGAGGCACGTCGGCTGCTGA
TGTCTAGATGAGTCCCCTGTAGGGTCAGAGACAATGTCAAACTGTTTACGTAATCAAGGTCAAGTGAGGGGAACAAGCGCAGCCAGTGAT
GAGTGAAGAAGAATCTGACCAGTATCTTGCAGTGTTGACGTTTCCCAGATGTGTGCTTGTGATGATACACACACATGCACAGGTTCTCAA
CCACGTGTGTATATATGTATGTGTGCATATGTCTGTAGCTGTATATAAAGCGCATGTAGAGCTACAGATCCAGATACACACACTTGTGTA
TATATGTACATACAGACATACTGAAGGGATTAGTACAATTTCTCCAAAGTACTGTACCTATCTTCAGCAAGAATGCAAAAGAAAATATTT
TCAATATATATACCTGGAACAGATTTTAATAATTATCAGAGTAATACCATTAATGGACAAATTGACTGCAATGTAATACTAGCTGGTATG
TTTCATAAATGTCAAGCTGTGGACCAACATATATAGCCTTTTATTATTTTTCTCTTCTTTTAAGTCAGTCTGTTATAAATTTTTTTTTAG
TCCCATAAGCAGTAGACTCCCACAGAAAATTTCTTCAAAATTTTTTGGTGTTCCAATGAATCTGGGATGTAAACTCTGAATGTATTTATA
ACTATTTATTTCTGGATGGTCATTATCTTGTAGCCAAATTTGACAATATAAAGTAAGGAGCAAAGTTACAGGCCAGTTTTTACTTGTTTG
CCCTGAGGGAAAAATCCTTTTAAAAAAAATTTCTGGTTTTTATTGGATTTTTGTATTTTAAATTTCAAATATTTTTCTACATCAAACCTA
GCAAAAATGGAGATGACGGTTTCTGATTTATAATAAATACTAGACAGTTTTCAGGCTCCTGTTAGACAAACACATTGATGAAGAAATTAG
TCTTAATAGGATTGTAGGCTGTGTAGAAAAGTTGGAAATATAGCACTTCATGGAGTCTTGTTTTGAAGATGACAGTTTTCTGTAACTACA
GCTTGGAAACTATGCAAATGGTCTAGATTCCTCAGAGCTCACATGATAGGATATAGTTAGTGATGACATTTTGCTCTTCTTGTGGGAACA
CACACTTCAAGGAGGAGATAGTGACTTTGAGATAGGAACAGTTTAAGATGCAGTGTGAGTCTGGCCTGCGTGCGGTGAGGAGGCCCCGCC
AAGAGACTGGTGGACATCTGACTGTGGGATGTGCTCTCAAGTAGGACGTCATCAGGACAGATTCTGAATAGGCATCATGAGAGTGCTGGT
CAGAAACGGCTGCCACTTTTTTTAATTTAATTTTATTTTTTATTTAAAGGAAGGAACAATAGCTAGGTAAGATTTTTATCAGCTTTCTCT
GTCTGAATCCAGTTTTTCCTCTGTCAGTCCTGGAAGCTTGAATAGAATTATATTGTTGAAGCCTTCAGGTCACAAACTGTCTTTTGTAAC
CTCCTGTCCCTCCTAAAACACGCCAACCCCTGCAGTCAAATCACATTAGTAATCTGATTTGCTGACAGTCCTGCCCTGCCTGCTCCTCGT
TTTCCCACATGTCCTGCATCCCTCCCCCACTGGAGTGATTTCAGTGAATCAGACAAGGAAGGATGTGTAGGATCACTACTGCATTGCAAT
ACCCTGTTATCCTCAGCAACAAAACCCACATTTCATACATCCTTTGTGTACTCAGGATAAAGACTGATGTTTACTCTCTGGGCACTGTTG
TAAGATAGGTTTTGTCAGAGCATAATCATTGTCTGCAAAGTGTTTGGTGCGAGGAAGATTATTGCTAATTTTGTGAAATAAAGAGTCTAG
CCCTCTCCTTTTAATGAACTTAACTCTCGCTGGCATCTGTAGTATCATTGGGAGCTTAGGCGCACATGGAAATGAGAGCCCGGCGCATGG
ATTTTAATGTTTTTCTAACAACTGTGGAGATTTGAGGGAATGTGTGGTGAATGTAAAATACCTAGTTTACTTGCCAGTCTCTTGTGTAAA

>98331_98331_2_VPS13D-PITPNB_VPS13D_chr1_12476754_ENST00000356315_PITPNB_chr22_28254502_ENST00000335272_length(amino acids)=4128AA_BP=4071
MLEGLVAWVLNTYLGKYVNNLNTDQLSVALLKGAVELENLPLKKDALKELELPFEVKAGFIGKVTLQIPFYRPHVDPWVISISSLHLIGA
PEKIQDFNDEKEKLLERERKKALLQALEEKWKNDRQQKGESYWYSVTASVVTRIVENIELKIQDVHLRFEDGVTNPSHPFAFGICIKNVS
MQNAVNEPVQKLMRKKQLDVAEFSIYWDVDCTLLGDLPQMELQEAMARSMESRSHHYVLEPVFASALLKRNCSKKPLRSRHSPRIDCDIQ
LETIPLKLSQLQYRQIMEFLKELERKERQVKFRRWKPKVAISKNCREWWYFALNANLYEIREQRKRCTWDFMLHRARDAVSYTDKYFNKL
KGGLLSTDDKEEMCRIEEEQSFEELKILRELVHDRFHKQEELAESLREPQFDSPGACPGAPEPGGGSGMLQYLQSWFPGWGGWYGQQTPE
GNVVEGLSAEQQEQWIPEEILGTEEFFDPTADASCMNTYTKRDHVFAKLNLQLQRGTVTLLHKEQGTPQMNESAFMQLEFSDVKLLAESL
PRRNSSLLSVRLGGLFLRDLATEGTMFPLLVFPNPQKEVGRVSQSFGLQTTSADRSDHYPAADPDGPVFEMLYERNPAHSHFERRLNVST
RPLNIIYNPQAIKKVADFFYKGKVHTSGFGYQSELELRVAEAARRQYNKLKMQTKAEIRQTLDRLLVGDFIEESKRWTVRLDISAPQVIF
PDDFKFKNPVLVVVDLGRMLLTNTQDNSRRKSRDGSASEETQFSDDEYKTPLATPPNTPPPESSSSNGEKTPPFSGVEFSEEQLQAHLMS
TKMYERYSLSFMDLQIMVGRVKDNWKHVQDIDVGPTHVVEKFNVHLQLERRLIYTSDPKYPGAVLSGNLPDLKIHINEDKISALKNCFAL
LTTPEMKTSDTQIKEKIFPQEEQRGSLQDSVMNLTQSIVLLEQHTREVLVESQLLLAEFKVNCMQLGVESNGRYISVLKVFGTNAHFVKR
PYDAEVSLTVHGLLLVDTMQTYGADFDLLMASHKNLSFDIPTGSLRDSRAQSPVSGPNVAHLTDGATLNDRSATSVSLDKILTKEQESLI
KLEYQFVSSECPSMNLDSTLQVISLQVNNLDIILNPETIVELIGFLQKSFPKEKDDLSPQPLMTDFERSFREQGTYQSTYEQNTEVAVEI
HRLNLLLLRTVGMANREKYGRKIATASIGGTKVNVSMGSTFDMNGSLGCLQLMDLTQDNVKNQYVVSIGNSVGYENIISDIGYFESVFVR
MEDAALTEALSFTFVERSKQECFLNLKMASLHYNHSAKFLKELTLSMDELEENFRGMLKSAATKVTTVLATKTAEYSEMVSLFETPRKTR
EPFILEENEIYGFDLASSHLDTVKLILNINIESPVVSIPRKPGSPELLVGHLGQIFIQNFVAGDDESRSDRLQVEIKDIKLYSLNCTQLA
GREAVGSEGSRMFCPPSGSGSANSQEEAHFTRHDFFESLHRGQAFHILNNTTIQFKLEKIPIERESELTFSLSPDDLGTSSIMKIEGKFV
NPVQVVLAKHVYEQVLQTLDNLVYSEDLNKYPASATSSPCPDSPLPPLSTCGESSVERKENGLFSHSSLSNTSQKSLSVKEVKSFTQIQA
TFCISELQVQLSGDLTLGAQGLVSLKFQDFEVEFSKDHPQTLSIQIALHSLLMEDLLEKNPDSKYKNLMVSRGAPKPSSLAQKEYLSQSC
PSVSNVEYPDMPRSLPSHMEEAPNVFQLYQRPTSASRKKQKEVQDKDYPLTPPPSPTVDEPKILVGKSKFDDSLVHINIFLVDKKHPEFS
SSYNRVNRSIDVDFNCLDVLITLQTWVVILDFFGIGSTADNHAMRLPPEGILHNVKLEPHASMESGLQDPVNTKLDLKVHSLSLVLNKTT
SELAKANVSKLVAHLEMIEGDLALQGSIGSLSLSDLTCHGEFYRERFTTSGEEALIFQTFKYGRPDPLLRREHDIRVSLRMASVQYVHTQ
RFQAEVVAFIQHFTQLQDVLGRQRAAIEGQTVRDQAQRCSRVLLDIEAGAPVLLIPESSRSNNLIVANLGKLKVKNKFLFAGFPGTFSLQ
DKESVPSASPTGIPKHSLRKTTSTEEPRGTHSQGQFTMPLAGMSLGSLKSEFVPSTSTKQQGPQPTLSVGQESSSPEDHVCLLDCVVVDL
QDMDIFAAERHPREYSKAPEDSSGDLIFPSYFVRQTGGSLLTEPCRLKLQVERNLDKEISHTVPDISIHGNLSSVHCSLDLYKYKLIRGL
LENNLGEPIEEFMRPYDLQDPRIHTVLSGEVYTCMCFLIDMVNVSLELKDPKRKEGAGSLARFDFKKCKLLYESFSNQTKSINLVSHSMM
AFDTRYAGQKTSPGMTNVFSCIFQPAKNSSTTQGSIQIELHFRSTKDSSCFTVVLNNLRVFLIFDWLLLVHDFLHTPSDIKKQNHVTPSR
HRNSSSESAIVPKTVKSGVVTKRSSLPVSNERHLEVKVNVTGTEFVVIEDVSCFDTNAIILKGTTVLTYKPRFVDRPFSGSLFGIEVFSC
RLGNEHDTALSIVDPVQIQMELVGNSSYQNSSGLMDAFNSEDFPPVLEIQLQALDIRLSYNDVQLFLAIAKSIPEQANAAVPDSVALESD
SVGTYLPGASRVGEEIREGTRHTLDPVLELQLARLQELGFSMDDCRKALLACQGQLKKAASWLFKNAEPLKSLSLASTSRDSPGAVAAPL
ISGVEIKAESVCICFIDDCMDCDVPLAELTFSRLNFLQRVRTSPEGYAHFTLSGDYYNRALSGWEPFIEPWPCSVSWQQQAASRLHPPRL
KLEAKAKPRLDINITSVLIDQYVSTKESWMADYCKDDKDIESAKSEDWMGSSVDPPCFGQTEVKTPKRRQPFVPFALRNHTGCTLWFATL
TTTPTRAALSHSGSPGVVPEGNGTFLDDTHNVSEWREVLTGEEIPFEFEARGKLRHRHTHDLRIHQLQVRVNGWEQVSPVSVDKVGTFFR
YAAPDKNSSSSTIGSPSSRTNIIHPQVYFSSLPPVRVVFAVTMEGSARKVITVRSALIVRNRLETPMELRLDSPSAPDKPVVLPAIMPGD
SFAVPLHLTSWRLQARPKGLGVFFCKAPIHWTNVVKTAEISSSKRECHSMDTEKSRFFRFCVAIKKENYPDYMPSNIFSDSAKQIFRQPG
HTIYLLPTVVICNLLPCELDFYVKGMPINGTLKPGKEAALHTADTSQNIELGVSLENFPLCKELLIPPGTQNYMVRMRLYDVNRRQLNLT
IRIVCRAEGSLKIFISAPYWLINKTGLPLIFRQDNAKTDAAGQFEEHELARSLSPLLFCYADKEQPNLCTMRIGRGIHPEGMPGWCQGFS
LDGGSGVRALKVIQQGNRPGLIYNIGIDVKKGRGRYIDTCMVIFAPRYLLDNKSSHKLAFAQREFARGQGTANPEGYISTLPGSSVVFHW
PRNDYDQLLCVRLMDVPNCIWSGGFEVNKNNSFHINMRDTLGKCFFLRVEITLRGATYRISFSDTDQLPPPFRIDNFSKVPVVFTQHGVA
EPRLRTEVKPMTSLDYAWDEPTLPPFITLTVKGAGSSEINCNMNDFQDNRQLYYENFIYIAATYTFSGLQEGTGRPVASNKAITCAELVL
DVSPKTQRVILKKKEPGKRSQLWRMTGTGMLAHEGSSVPHNPNKPSAARSTEGSAILDIAGLAAVTDNRYEPLMLRKPDRRRSTTQTWSF
REGKLTCGLHGLVVQAKGGLSGLFDGAEVVLGPDTSMELLGPVPPEQQFINQKMRPGSGMLSIRVIPDGPTRALQITDFCHRKSSRSYEV
DELPVTEQELQKLKNPDTEQELEVLVRLEGGIGLSLINKVPEELVFASLTGINVHYTQLATSHMLELSIQDVQVDNQLIGTTQPFMLYVT
PLSNENEVIETGPAVQVNAVKFPSKSALTNIYKHLMITAQRFTVQIEEKLLLKLLSFFGYDQAESEVEKYDENLHEKTAEQGGTPIRYYF
ENLKISIPQIKLSVFTSNKLPLDLKALKSTLGFPLIRFEDAVINLDPFTRVHPYETKEFIINDILKHFQEFLGNPMGLLNDVSEGVTGLI

--------------------------------------------------------------
>98331_98331_3_VPS13D-PITPNB_VPS13D_chr1_12476754_ENST00000356315_PITPNB_chr22_28254502_ENST00000455418_length(transcript)=14547nt_BP=12346nt
GGAGGAAACGCCGCGCAGCGCCGGGCTGGGGCGGGCGGCCCGGGACACCGACAGATTTTTCTGTGACCATGAAAGAGAGAAATAAAGAAT
GATCCATGATTTCTAAACACCTTTTCCTGAGGATATAGTCATGTTGGAAGGCCTTGTAGCCTGGGTTCTCAATACCTATTTGGGAAAATA
TGTCAATAACCTGAACACTGACCAGCTCTCAGTTGCACTTCTCAAAGGTGCTGTTGAATTAGAAAACTTGCCATTAAAGAAAGATGCCTT
GAAAGAATTGGAATTACCATTTGAAGTCAAAGCTGGCTTCATTGGGAAAGTAACCCTTCAGATTCCCTTTTATCGCCCCCATGTGGACCC
TTGGGTGATCTCCATCTCCAGCCTTCACTTAATTGGAGCCCCAGAGAAAATACAGGATTTCAATGATGAAAAGGAGAAGCTGTTGGAAAG
GGAACGTAAGAAAGCACTACTTCAAGCCCTGGAGGAGAAATGGAAGAATGACCGCCAGCAGAAAGGGGAGTCCTATTGGTATTCAGTTAC
CGCCTCCGTAGTTACAAGGATTGTGGAGAATATTGAATTAAAAATTCAAGATGTCCATTTACGCTTTGAAGATGGTGTCACCAATCCCTC
CCATCCTTTTGCTTTTGGCATCTGCATTAAGAATGTGTCCATGCAAAATGCTGTGAATGAGCCTGTACAGAAACTAATGCGGAAAAAGCA
ATTAGACGTAGCAGAATTTAGCATCTATTGGGATGTCGATTGCACTTTACTGGGGGATTTGCCTCAGATGGAGTTACAGGAGGCCATGGC
CAGGAGCATGGAGAGTCGCAGCCATCACTACGTCCTGGAGCCTGTGTTTGCATCTGCTCTTTTGAAGAGAAACTGCTCCAAGAAGCCCCT
GCGGTCTCGGCACAGTCCCCGTATTGATTGTGATATTCAGCTGGAGACCATTCCCTTGAAACTCTCTCAGCTGCAATACCGGCAAATCAT
GGAATTCCTCAAGGAGCTGGAACGAAAGGAGAGGCAGGTGAAGTTCCGAAGGTGGAAACCCAAGGTGGCGATATCTAAGAACTGCCGAGA
ATGGTGGTATTTTGCTTTGAATGCTAACTTGTATGAGATCAGAGAGCAGAGGAAACGTTGCACCTGGGACTTTATGTTGCACCGCGCTCG
TGATGCTGTATCTTACACTGACAAATATTTCAACAAGTTAAAAGGAGGCCTGCTGTCCACAGATGACAAGGAGGAAATGTGTCGGATTGA
AGAGGAACAGAGCTTTGAGGAATTGAAGATTTTGCGTGAACTGGTTCATGATCGATTTCACAAACAGGAAGAACTAGCAGAGAGTCTGCG
GGAGCCTCAGTTTGATTCTCCAGGAGCCTGTCCGGGAGCCCCAGAACCCGGTGGAGGCAGTGGGATGCTGCAGTATCTCCAGTCCTGGTT
TCCTGGATGGGGTGGCTGGTACGGGCAGCAGACCCCAGAAGGGAATGTGGTTGAGGGACTGTCAGCAGAGCAACAGGAGCAGTGGATTCC
TGAAGAGATCCTGGGCACTGAGGAGTTTTTTGACCCCACTGCAGATGCCTCGTGTATGAACACGTATACAAAGCGAGATCATGTCTTTGC
CAAACTGAATTTGCAGTTGCAGCGAGGTACAGTGACTCTGTTACACAAGGAGCAAGGAACTCCTCAAATGAATGAAAGTGCTTTCATGCA
GCTCGAGTTTTCAGATGTAAAACTTCTAGCAGAGTCTCTTCCTCGAAGAAATTCCTCGTTGCTTTCAGTCCGGTTGGGTGGACTGTTTCT
TCGAGACCTGGCTACAGAAGGAACTATGTTTCCTCTTCTAGTCTTCCCTAATCCACAAAAAGAAGTTGGCAGAGTCTCACAATCTTTTGG
TCTACAAACTACATCTGCAGACAGAAGTGATCATTACCCAGCTGCAGATCCAGATGGCCCCGTTTTTGAGATGCTGTATGAGAGAAATCC
GGCGCACAGCCACTTTGAGAGGCGGCTCAATGTCAGCACAAGGCCCTTGAACATCATATACAATCCGCAGGCCATTAAAAAAGTAGCAGA
CTTTTTCTACAAGGGAAAGGTTCATACCTCAGGTTTTGGTTATCAGTCTGAACTTGAGCTGAGAGTGGCTGAAGCTGCCCGAAGACAATA
TAACAAGCTGAAGATGCAGACCAAGGCAGAAATCCGGCAAACTCTTGATCGTTTGCTAGTGGGTGATTTCATTGAGGAGAGTAAACGATG
GACCGTGCGGCTGGATATTTCTGCCCCTCAGGTGATATTTCCTGATGATTTCAAATTCAAGAATCCTGTGTTAGTTGTCGTGGATCTAGG
AAGAATGCTTTTGACGAACACCCAAGATAACTCCAGGAGGAAAAGTAGGGATGGGTCAGCATCTGAAGAGACCCAGTTTAGTGATGATGA
ATATAAGACCCCCCTGGCCACACCTCCTAACACCCCACCTCCCGAGTCAAGCAGCAGCAACGGAGAGAAAACACCTCCCTTTTCTGGAGT
TGAGTTCAGTGAAGAACAGCTTCAAGCACATTTAATGAGCACAAAGATGTATGAGAGGTACTCGCTGTCATTTATGGACCTCCAGATCAT
GGTTGGACGAGTGAAAGACAATTGGAAGCATGTCCAGGATATTGACGTGGGACCAACACATGTGGTAGAGAAGTTCAACGTTCACCTACA
GTTAGAGCGTCGATTGATTTATACTTCAGATCCCAAATATCCAGGAGCCGTGCTCTCAGGCAACTTACCAGACTTAAAAATCCACATTAA
TGAAGATAAAATATCTGCACTAAAGAATTGCTTTGCTCTCCTCACCACCCCAGAAATGAAAACTTCTGACACTCAGATTAAAGAAAAGAT
TTTTCCCCAGGAGGAGCAGCGGGGAAGTTTGCAAGACTCCGTAATGAATTTAACCCAGAGCATTGTGTTGTTGGAGCAGCATACCCGCGA
GGTTCTGGTGGAGTCGCAGCTCCTCCTGGCGGAATTTAAAGTGAACTGTATGCAGCTTGGTGTTGAGAGCAATGGCCGGTACATTTCTGT
GCTCAAGGTGTTTGGTACCAATGCTCACTTTGTGAAGAGGCCTTATGATGCTGAAGTCTCCCTAACTGTTCATGGTTTGCTCCTGGTGGA
TACCATGCAGACATATGGTGCTGATTTTGACCTTTTGATGGCTTCACATAAGAACTTGAGCTTTGATATTCCAACGGGAAGCCTTCGGGA
TAGCAGGGCCCAGTCTCCTGTCTCTGGACCGAATGTGGCCCACTTAACTGATGGAGCTACACTGAACGACCGATCAGCTACTAGTGTTTC
ACTTGACAAAATTCTTACCAAAGAGCAAGAGTCCCTTATTAAGTTGGAATATCAGTTTGTGAGTTCAGAGTGCCCATCGATGAATTTAGA
CAGTACTCTTCAGGTGATTTCCCTACAGGTGAATAATTTAGATATTATCCTCAATCCAGAGACGATTGTGGAGCTAATTGGTTTTCTTCA
AAAATCCTTTCCCAAGGAAAAAGATGATTTAAGTCCTCAACCTTTAATGACTGATTTTGAAAGAAGCTTCAGAGAACAAGGAACTTACCA
GTCTACATATGAACAAAACACTGAGGTTGCAGTGGAAATCCATAGGCTGAACTTACTGCTTCTTCGGACAGTGGGCATGGCAAATAGAGA
GAAATATGGCAGAAAAATTGCAACTGCAAGTATAGGTGGCACCAAAGTTAATGTCTCAATGGGTAGCACGTTTGACATGAATGGTTCTCT
TGGCTGTTTACAGCTTATGGATTTGACACAAGATAACGTTAAAAACCAGTATGTTGTCAGCATTGGGAATTCTGTAGGCTATGAAAATAT
CATCAGTGATATTGGCTACTTTGAATCTGTGTTTGTCAGAATGGAAGATGCAGCCCTCACTGAAGCTTTGAGTTTCACGTTTGTTGAGAG
ATCTAAACAGGAGTGTTTTCTCAACCTGAAGATGGCTTCTTTACATTATAACCACTCTGCTAAGTTTTTGAAGGAGTTGACGTTATCCAT
GGATGAACTGGAAGAAAATTTTCGAGGTATGCTGAAAAGCGCAGCCACCAAAGTCACCACAGTACTAGCTACCAAGACTGCCGAGTATAG
CGAGATGGTATCGCTCTTTGAAACTCCAAGGAAGACTCGGGAACCCTTTATCTTAGAGGAAAATGAAATATATGGGTTTGACCTAGCTTC
GTCTCATTTGGACACTGTAAAGCTAATCTTGAACATAAACATTGAATCACCAGTTGTTTCTATCCCTCGGAAGCCGGGGAGTCCTGAGTT
GTTGGTGGGACACTTGGGACAGATATTCATCCAGAATTTTGTGGCGGGAGATGATGAATCCAGAAGTGACCGTCTGCAGGTGGAAATCAA
GGACATTAAACTGTATTCTTTGAATTGCACCCAGTTGGCAGGTAGAGAAGCTGTTGGGTCTGAAGGAAGCCGGATGTTTTGCCCACCTTC
CGGGTCTGGCAGTGCCAACAGTCAGGAGGAAGCTCATTTCACACGACATGATTTCTTTGAATCTTTGCATAGAGGTCAAGCTTTTCACAT
CCTGAACAACACCACCATTCAGTTTAAACTGGAGAAGATCCCTATAGAGAGAGAATCTGAATTGACTTTTTCTCTTAGCCCAGATGACCT
GGGAACTTCTAGCATCATGAAGATTGAAGGAAAATTTGTCAATCCAGTTCAGGTGGTGTTAGCAAAGCATGTATATGAGCAGGTTTTACA
AACCCTGGACAATCTCGTGTACAGTGAAGATCTGAATAAGTATCCAGCCAGTGCTACCTCCTCCCCTTGCCCTGATTCTCCTCTGCCTCC
CCTCAGTACCTGTGGAGAATCTTCTGTTGAAAGGAAGGAGAATGGATTGTTCAGCCACTCCAGCCTTTCTAACACCTCTCAGAAGTCATT
GTCAGTGAAGGAAGTCAAATCCTTTACTCAGATTCAAGCCACCTTTTGTATATCAGAGCTTCAGGTTCAGCTAAGTGGAGATCTGACTTT
GGGGGCCCAAGGTCTTGTGAGCTTAAAGTTTCAGGACTTTGAGGTGGAATTCAGTAAAGACCATCCCCAGACTTTATCTATTCAGATTGC
CCTGCATTCTCTGCTGATGGAGGACTTATTGGAGAAGAATCCAGATTCTAAATATAAGAACCTGATGGTGTCTCGAGGAGCCCCTAAGCC
ATCTAGTTTAGCACAAAAAGAATACCTTTCTCAGTCTTGCCCCTCAGTGTCCAATGTGGAATATCCTGATATGCCTCGGTCTCTCCCTTC
CCACATGGAAGAAGCTCCTAATGTCTTCCAGTTGTATCAAAGGCCCACCTCTGCGTCCCGGAAAAAGCAAAAGGAAGTCCAAGACAAGGA
CTATCCCTTGACCCCACCTCCTTCTCCAACAGTGGATGAGCCCAAGATACTTGTTGGAAAGAGTAAATTTGATGATTCCTTAGTCCACAT
CAACATATTCTTGGTAGATAAGAAACATCCAGAATTCTCTTCCAGTTACAATCGAGTTAACCGGAGCATTGATGTTGATTTTAATTGCTT
GGATGTGCTGATCACACTGCAAACCTGGGTTGTGATATTAGACTTTTTTGGAATCGGCTCCACTGCAGACAACCACGCAATGAGGCTGCC
TCCTGAGGGCATTCTGCACAACGTGAAGTTGGAGCCACATGCCTCCATGGAGTCTGGACTTCAGGATCCAGTGAACACCAAACTGGATCT
CAAGGTTCATTCACTTTCTCTAGTGCTGAATAAGACCACCAGTGAGCTTGCCAAAGCAAATGTGTCCAAATTAGTAGCACACCTGGAAAT
GATTGAGGGAGACCTGGCCTTACAGGGCAGCATTGGGAGTCTGTCTCTAAGTGACCTCACATGCCATGGAGAGTTCTACAGAGAACGGTT
CACTACCAGTGGTGAAGAAGCACTCATCTTCCAGACTTTTAAATACGGACGGCCTGACCCTCTGCTCCGGAGAGAACACGACATTCGCGT
GAGCCTCCGGATGGCCTCTGTGCAGTATGTGCATACTCAGCGTTTCCAGGCAGAGGTGGTGGCCTTCATTCAGCATTTCACTCAGCTGCA
GGATGTCTTAGGGCGCCAGCGAGCTGCTATTGAGGGGCAGACGGTGAGAGATCAAGCCCAGCGCTGTTCACGGGTTCTCCTGGATATTGA
GGCTGGTGCTCCCGTTCTCTTGATCCCAGAAAGTTCCAGATCAAATAATCTGATTGTAGCAAATTTGGGGAAGTTGAAAGTCAAAAATAA
GTTTCTGTTTGCTGGTTTTCCTGGCACCTTTTCCCTACAAGATAAGGAATCTGTGCCTTCAGCTTCCCCAACGGGTATTCCCAAACACAG
TCTGAGGAAAACGACAAGCACGGAGGAGCCCAGGGGAACCCATTCCCAGGGGCAGTTCACGATGCCTCTTGCTGGAATGAGCCTAGGAAG
CCTGAAGAGTGAGTTTGTGCCCAGTACCTCCACCAAGCAGCAAGGGCCGCAACCCACACTGTCTGTTGGCCAAGAGTCCAGTAGTCCAGA
AGACCATGTCTGCCTGCTGGATTGCGTTGTCGTGGATCTCCAGGACATGGACATCTTTGCTGCAGAGAGACATCCGAGAGAATACTCGAA
GGCACCAGAGGATAGTAGTGGAGATCTGATCTTCCCTTCCTATTTTGTGCGACAGACAGGAGGAAGCCTCTTAACCGAGCCTTGTAGGCT
GAAATTGCAGGTGGAAAGGAATTTGGACAAAGAAATAAGTCATACTGTGCCAGACATATCTATCCATGGCAATCTCTCCTCAGTCCACTG
CTCTCTGGATCTGTATAAATACAAGCTGATCCGCGGCTTATTAGAGAACAACCTGGGAGAACCCATAGAGGAATTTATGCGGCCTTATGA
TTTACAAGATCCAAGAATTCATACTGTCCTGAGTGGAGAAGTGTACACCTGTATGTGCTTCCTCATTGATATGGTGAATGTAAGTCTGGA
GCTTAAAGATCCAAAAAGAAAAGAAGGTGCTGGGTCCCTAGCCAGATTTGACTTCAAGAAATGCAAACTGCTCTATGAAAGTTTTTCCAA
CCAAACCAAGTCCATTAACTTGGTTTCCCATTCCATGATGGCTTTTGACACCCGTTATGCTGGGCAGAAGACCAGCCCTGGCATGACGAA
TGTGTTCAGCTGTATCTTTCAGCCCGCTAAGAACAGCAGCACCACCCAAGGGTCCATTCAGATTGAACTACATTTCAGATCTACCAAGGA
TTCCTCCTGCTTTACAGTAGTTCTCAACAATCTCCGTGTGTTTCTCATATTTGACTGGCTACTGTTAGTCCATGATTTTCTCCACACTCC
CAGTGATATTAAGAAACAAAATCATGTTACTCCTTCTCGCCACCGTAACTCTAGCAGCGAATCTGCTATAGTTCCCAAAACTGTGAAGAG
TGGAGTAGTTACCAAGCGGTCTTCCCTTCCTGTGTCCAATGAAAGGCACCTGGAGGTCAAGGTCAATGTAACAGGTACGGAGTTTGTGGT
CATTGAAGATGTGTCCTGCTTCGACACCAATGCCATTATTCTGAAAGGCACCACAGTGCTCACCTATAAGCCCCGGTTTGTTGATCGCCC
CTTTTCAGGAAGTTTGTTTGGCATTGAGGTGTTTTCATGCCGACTAGGGAATGAGCATGATACAGCTCTTTCAATTGTGGATCCCGTACA
AATTCAAATGGAGTTGGTGGGGAATTCTTCTTATCAAAATAGTTCAGGATTGATGGATGCATTCAATAGTGAAGATTTCCCACCTGTCCT
GGAGATTCAGTTACAAGCCCTGGATATCAGACTCTCCTATAATGATGTTCAGCTGTTTCTTGCCATTGCAAAATCCATCCCAGAGCAAGC
TAATGCTGCAGTGCCAGACTCAGTGGCCCTGGAGTCAGACTCCGTTGGCACTTACCTTCCAGGTGCATCTCGCGTTGGAGAGGAAATCAG
AGAAGGGACAAGACACACCTTAGATCCTGTCTTGGAGTTACAGCTGGCTAGGCTGCAGGAGCTGGGATTCAGCATGGATGATTGTCGCAA
AGCTCTTTTGGCGTGTCAAGGCCAATTGAAAAAGGCAGCAAGTTGGTTGTTTAAGAATGCGGAACCTCTGAAGTCTCTTTCCTTGGCCTC
CACCAGCCGAGATAGCCCAGGGGCTGTGGCAGCGCCATTGATCTCTGGCGTGGAGATCAAAGCTGAGAGTGTGTGCATCTGTTTCATCGA
TGACTGCATGGATTGTGATGTTCCTCTCGCTGAACTCACCTTTTCCCGTCTGAATTTTCTTCAGCGTGTAAGAACTAGCCCTGAAGGCTA
TGCCCACTTCACCCTTTCTGGAGATTATTATAACCGTGCTCTTTCAGGCTGGGAGCCATTTATTGAGCCTTGGCCATGCTCTGTATCCTG
GCAACAGCAGGCAGCTAGTCGTCTCCATCCTCCTCGACTGAAGCTAGAAGCCAAGGCCAAACCTCGTTTGGATATCAATATCACTTCTGT
GCTAATTGACCAGTATGTAAGTACCAAGGAATCGTGGATGGCAGATTACTGTAAAGATGACAAGGACATAGAGTCAGCTAAATCAGAAGA
CTGGATGGGCTCTTCGGTGGATCCTCCATGTTTTGGACAAACAGAGGTGAAAACCCCCAAGCGCCGGCAGCCATTTGTCCCCTTTGCTCT
GAGGAACCACACGGGGTGCACTTTGTGGTTTGCCACCCTGACCACCACACCCACCAGAGCTGCACTCTCTCACAGTGGGAGTCCAGGGGT
AGTTCCAGAAGGGAACGGAACATTTCTCGATGATACTCACAATGTTAGTGAATGGCGAGAAGTCCTTACAGGTGAAGAGATTCCCTTTGA
ATTTGAAGCAAGAGGAAAGTTAAGACACAGACACACCCATGACCTCCGGATTCATCAACTGCAAGTGAGAGTAAATGGCTGGGAGCAAGT
GAGCCCAGTGTCTGTGGACAAAGTCGGGACCTTTTTTCGATATGCAGCACCAGATAAAAATTCATCTTCCTCTACGATTGGCAGCCCAAG
CAGCAGAACAAATATTATACATCCCCAGGTTTATTTCTCTTCACTCCCACCAGTGCGGGTGGTCTTTGCAGTGACTATGGAAGGCAGTGC
ACGGAAAGTCATCACTGTCCGGTCAGCCCTCATTGTGAGGAACAGACTTGAGACACCAATGGAACTAAGACTGGATAGCCCATCAGCTCC
AGACAAGCCAGTGGTGCTTCCTGCTATCATGCCAGGGGATTCGTTTGCTGTGCCTTTACACCTCACTTCTTGGCGGCTACAGGCCCGGCC
CAAAGGATTGGGTGTATTTTTCTGTAAGGCTCCCATTCATTGGACCAATGTAGTGAAGACTGCAGAAATTAGTAGCAGTAAACGAGAGTG
CCACTCTATGGACACAGAAAAAAGCCGATTTTTCAGGTTTTGTGTGGCTATAAAGAAAGAGAATTATCCAGATTATATGCCCTCAAACAT
ATTTTCTGACAGTGCAAAACAGATTTTCAGACAGCCTGGGCATACCATATATCTCCTGCCAACTGTGGTAATCTGCAACTTGCTACCCTG
TGAACTTGATTTTTATGTTAAAGGAATGCCAATTAATGGGACGCTGAAACCTGGCAAGGAGGCAGCTCTCCATACAGCTGATACATCCCA
GAACATTGAGCTGGGGGTATCACTGGAGAATTTCCCCCTCTGTAAAGAATTGCTCATTCCACCTGGAACCCAAAACTATATGGTGAGAAT
GCGACTCTATGACGTCAACCGTCGGCAGCTGAACCTCACCATCCGGATTGTGTGTCGAGCAGAAGGATCCTTAAAGATCTTCATTTCTGC
TCCATATTGGCTGATTAACAAAACAGGGTTGCCACTGATCTTCAGACAGGACAATGCCAAGACAGATGCTGCAGGCCAGTTTGAGGAGCA
TGAGCTGGCCCGTAGCCTGAGTCCTCTCTTATTCTGCTATGCTGACAAAGAGCAGCCAAACCTCTGCACGATGAGAATCGGAAGGGGGAT
TCATCCAGAAGGCATGCCGGGCTGGTGTCAGGGCTTCTCCCTGGATGGTGGTAGTGGTGTCCGAGCTTTGAAAGTCATCCAGCAAGGAAA
CCGCCCAGGGCTGATCTATAACATTGGTATTGATGTCAAGAAAGGCCGAGGTCGATACATTGATACCTGCATGGTCATCTTTGCCCCCCG
TTACCTGTTAGATAATAAATCATCTCACAAGCTTGCATTTGCACAGAGGGAATTTGCCAGGGGACAGGGAACAGCCAATCCCGAAGGTTA
CATTTCCACCCTTCCTGGTTCCAGTGTGGTGTTCCACTGGCCTCGGAATGACTATGATCAGCTATTGTGTGTCAGACTGATGGACGTTCC
CAATTGTATTTGGTCTGGAGGCTTTGAAGTCAACAAGAATAATTCCTTCCATATCAACATGAGGGATACCTTGGGAAAATGCTTCTTCCT
ACGAGTGGAAATTACTCTCCGAGGAGCTACGTATAGGATCTCATTTAGTGACACAGATCAGTTACCTCCTCCTTTCCGAATTGACAACTT
TTCTAAGGTCCCGGTTGTCTTTACTCAGCATGGCGTAGCTGAACCCAGGCTCCGGACTGAAGTGAAGCCCATGACTTCATTGGATTATGC
CTGGGACGAACCCACCTTGCCACCTTTTATCACTCTGACTGTTAAAGGGGCAGGGTCCTCTGAGATCAACTGCAACATGAATGATTTCCA
GGATAATCGGCAGCTTTATTATGAAAATTTCATTTACATTGCTGCTACATATACATTCTCTGGCTTGCAGGAGGGAACAGGCAGGCCTGT
GGCTTCCAACAAGGCCATTACCTGTGCGGAGCTCGTTTTGGATGTCTCACCCAAGACACAAAGAGTCATTTTAAAAAAGAAGGAACCAGG
AAAGCGTTCTCAGCTGTGGAGGATGACAGGAACAGGAATGCTGGCCCATGAGGGCTCCTCAGTTCCTCACAATCCCAATAAGCCCTCAGC
CGCCCGCTCCACCGAGGGGTCTGCCATCTTAGATATTGCTGGTCTCGCTGCAGTGACTGACAACAGATACGAGCCACTGATGCTGAGAAA
GCCTGACCGCAGGCGAAGCACAACTCAGACGTGGAGTTTCCGAGAAGGAAAACTGACCTGTGGGTTACATGGGTTGGTCGTCCAGGCCAA
AGGAGGACTTTCTGGTTTGTTTGATGGAGCTGAAGTTGTTCTTGGTCCTGACACTTCCATGGAGCTTTTGGGGCCAGTTCCACCTGAACA
ACAATTTATTAATCAAAAAATGAGACCTGGTTCTGGAATGTTATCCATCAGAGTCATCCCAGATGGACCAACTAGAGCACTCCAGATAAC
AGATTTCTGCCACCGGAAAAGCAGCCGTTCATATGAAGTGGATGAACTTCCTGTCACCGAACAAGAGCTGCAGAAATTAAAGAATCCAGA
TACAGAGCAGGAATTGGAAGTGCTTGTGAGGTTAGAAGGTGGAATTGGGTTGTCCTTAATTAATAAAGTCCCAGAAGAACTGGTCTTTGC
AAGTCTTACAGGAATCAATGTGCACTATACACAGCTGGCAACCAGTCACATGCTTGAACTCAGCATACAGGATGTACAGGTGGACAATCA
GCTCATTGGTACCACGCAGCCCTTCATGCTCTATGTGACTCCCCTGAGCAATGAGAATGAGGTCATCGAGACCGGCCCAGCTGTGCAAGT
CAACGCAGTGAAGTTCCCCAGTAAGAGTGCACTGACCAACATCTACAAGCATCTGATGATCACAGCTCAGAGATTCACAGTGCAAATTGA
GGAGAAACTGCTCCTCAAGCTGCTAAGTTTCTTTGGCTACGATCAAGCAGAATCAGAGGTGGAAAAATATGATGAAAACCTCCATGAAAA
GACAGCTGAGCAAGGTGGAACACCAATTCGATACTACTTTGAAAATCTCAAAATCAGCATTCCTCAGATCAAGCTAAGTGTGTTCACCTC
CAACAAGCTCCCATTGGATCTTAAGGCCCTAAAAAGCACCTTGGGGTTTCCTTTGATACGGTTTGAAGACGCTGTGATTAATCTAGATCC
ATTCACTCGGGTACATCCCTATGAGACCAAGGAGTTCATCATCAATGATATCCTCAAACATTTCCAGGAGTTTCTTGGCAATCCTATGGG
GCTTTTGAATGATGTTTCTGAAGGGGTTACTGGACTGATAAAATATGGAAATGTCGGGGGCCTCATCAGAAATGTTACACACGGAGTATC
AAACTCTGCTGCCAAGCAAGAAAAACGGATATTTACAAACTTCCATCGCCAGCTTTTTTGTTGGATTGACAAGTGGATCGATCTCACGAT
GGAAGACATTAGGAGAATGGAAGACGAGACTCAGAAAGAACTAGAAACAATGCGTAAGAGGGGTTCCGTTCGAGGCACGTCGGCTGCTGA
TGTCTAGATGAGTCCCCTGTAGGGTCAGAGACAATGTCAAACTGTTTACGTAATCAAGGTCAAGTGAGGGGAACAAGCGCAGCCAGTGAT
GAGTGAAGAAGAATCTGACCAGTATCTTGCAGTGTTGACGTTTCCCAGATGTGTGCTTGTGATGATACACACACATGCACAGGTTCTCAA
CCACGTGTGTATATATGTATGTGTGCATATGTCTGTAGCTGTATATAAAGCGCATGTAGAGCTACAGATCCAGATACACACACTTGTGTA
TATATGTACATACAGACATACTGAAGGGATTAGTACAATTTCTCCAAAGTACTGTACCTATCTTCAGCAAGAATGCAAAAGAAAATATTT
TCAATATATATACCTGGAACAGATTTTAATAATTATCAGAGTAATACCATTAATGGACAAATTGACTGCAATGTAATACTAGCTGGTATG
TTTCATAAATGTCAAGCTGTGGACCAACATATATAGCCTTTTATTATTTTTCTCTTCTTTTAAGTCAGTCTGTTATAAATTTTTTTTTAG
TCCCATAAGCAGTAGACTCCCACAGAAAATTTCTTCAAAATTTTTTGGTGTTCCAATGAATCTGGGATGTAAACTCTGAATGTATTTATA
ACTATTTATTTCTGGATGGTCATTATCTTGTAGCCAAATTTGACAATATAAAGTAAGGAGCAAAGTTACAGGCCAGTTTTTACTTGTTTG
CCCTGAGGGAAAAATCCTTTTAAAAAAAATTTCTGGTTTTTATTGGATTTTTGTATTTTAAATTTCAAATATTTTTCTACATCAAACCTA
GCAAAAATGGAGATGACGGTTTCTGATTTATAATAAATACTAGACAGTTTTCAGGCTCCTGTTAGACAAACACATTGATGAAGAAATTAG
TCTTAATAGGATTGTAGGCTGTGTAGAAAAGTTGGAAATATAGCACTTCATGGAGTCTTGTTTTGAAGATGACAGTTTTCTGTAACTACA
GCTTGGAAACTATGCAAATGGTCTAGATTCCTCAGAGCTCACATGATAGGATATAGTTAGTGATGACATTTTGCTCTTCTTGTGGGAACA
CACACTTCAAGGAGGAGATAGTGACTTTGAGATAGGAACAGTTTAAGATGCAGTGTGAGTCTGGCCTGCGTGCGGTGAGGAGGCCCCGCC
AAGAGACTGGTGGACATCTGACTGTGGGATGTGCTCTCAAGTAGGACGTCATCAGGACAGATTCTGAATAGGCATCATGAGAGTGCTGGT
CAGAAACGGCTGCCACTTTTTTTAATTTAATTTTATTTTTTATTTAAAGGAAGGAACAATAGCTAGGTAAGATTTTTATCAGCTTTCTCT
GTCTGAATCCAGTTTTTCCTCTGTCAGTCCTGGAAGCTTGAATAGAATTATATTGTTGAAGCCTTCAGGTCACAAACTGTCTTTTGTAAC
CTCCTGTCCCTCCTAAAACACGCCAACCCCTGCAGTCAAATCACATTAGTAATCTGATTTGCTGACAGTCCTGCCCTGCCTGCTCCTCGT
TTTCCCACATGTCCTGCATCCCTCCCCCACTGGAGTGATTTCAGTGAATCAGACAAGGAAGGATGTGTAGGATCACTACTGCATTGCAAT
ACCCTGTTATCCTCAGCAACAAAACCCACATTTCATACATCCTTTGTGTACTCAGGATAAAGACTGATGTTTACTCTCTGGGCACTGTTG
TAAGATAGGTTTTGTCAGAGCATAATCATTGTCTGCAAAGTGTTTGGTGCGAGGAAGATTATTGCTAATTTTGTGAAATAAAGAGTCTAG
CCCTCTCCTTTTAATGAACTTAACTCTCGCTGGCATCTGTAGTATCATTGGGAGCTTAGGCGCACATGGAAATGAGAGCCCGGCGCATGG
ATTTTAATGTTTTTCTAACAACTGTGGAGATTTGAGGGAATGTGTGGTGAATGTAAAATACCTAGTTTACTTGCCAGTCTCTTGTGTAAA

>98331_98331_3_VPS13D-PITPNB_VPS13D_chr1_12476754_ENST00000356315_PITPNB_chr22_28254502_ENST00000455418_length(amino acids)=4128AA_BP=4071
MLEGLVAWVLNTYLGKYVNNLNTDQLSVALLKGAVELENLPLKKDALKELELPFEVKAGFIGKVTLQIPFYRPHVDPWVISISSLHLIGA
PEKIQDFNDEKEKLLERERKKALLQALEEKWKNDRQQKGESYWYSVTASVVTRIVENIELKIQDVHLRFEDGVTNPSHPFAFGICIKNVS
MQNAVNEPVQKLMRKKQLDVAEFSIYWDVDCTLLGDLPQMELQEAMARSMESRSHHYVLEPVFASALLKRNCSKKPLRSRHSPRIDCDIQ
LETIPLKLSQLQYRQIMEFLKELERKERQVKFRRWKPKVAISKNCREWWYFALNANLYEIREQRKRCTWDFMLHRARDAVSYTDKYFNKL
KGGLLSTDDKEEMCRIEEEQSFEELKILRELVHDRFHKQEELAESLREPQFDSPGACPGAPEPGGGSGMLQYLQSWFPGWGGWYGQQTPE
GNVVEGLSAEQQEQWIPEEILGTEEFFDPTADASCMNTYTKRDHVFAKLNLQLQRGTVTLLHKEQGTPQMNESAFMQLEFSDVKLLAESL
PRRNSSLLSVRLGGLFLRDLATEGTMFPLLVFPNPQKEVGRVSQSFGLQTTSADRSDHYPAADPDGPVFEMLYERNPAHSHFERRLNVST
RPLNIIYNPQAIKKVADFFYKGKVHTSGFGYQSELELRVAEAARRQYNKLKMQTKAEIRQTLDRLLVGDFIEESKRWTVRLDISAPQVIF
PDDFKFKNPVLVVVDLGRMLLTNTQDNSRRKSRDGSASEETQFSDDEYKTPLATPPNTPPPESSSSNGEKTPPFSGVEFSEEQLQAHLMS
TKMYERYSLSFMDLQIMVGRVKDNWKHVQDIDVGPTHVVEKFNVHLQLERRLIYTSDPKYPGAVLSGNLPDLKIHINEDKISALKNCFAL
LTTPEMKTSDTQIKEKIFPQEEQRGSLQDSVMNLTQSIVLLEQHTREVLVESQLLLAEFKVNCMQLGVESNGRYISVLKVFGTNAHFVKR
PYDAEVSLTVHGLLLVDTMQTYGADFDLLMASHKNLSFDIPTGSLRDSRAQSPVSGPNVAHLTDGATLNDRSATSVSLDKILTKEQESLI
KLEYQFVSSECPSMNLDSTLQVISLQVNNLDIILNPETIVELIGFLQKSFPKEKDDLSPQPLMTDFERSFREQGTYQSTYEQNTEVAVEI
HRLNLLLLRTVGMANREKYGRKIATASIGGTKVNVSMGSTFDMNGSLGCLQLMDLTQDNVKNQYVVSIGNSVGYENIISDIGYFESVFVR
MEDAALTEALSFTFVERSKQECFLNLKMASLHYNHSAKFLKELTLSMDELEENFRGMLKSAATKVTTVLATKTAEYSEMVSLFETPRKTR
EPFILEENEIYGFDLASSHLDTVKLILNINIESPVVSIPRKPGSPELLVGHLGQIFIQNFVAGDDESRSDRLQVEIKDIKLYSLNCTQLA
GREAVGSEGSRMFCPPSGSGSANSQEEAHFTRHDFFESLHRGQAFHILNNTTIQFKLEKIPIERESELTFSLSPDDLGTSSIMKIEGKFV
NPVQVVLAKHVYEQVLQTLDNLVYSEDLNKYPASATSSPCPDSPLPPLSTCGESSVERKENGLFSHSSLSNTSQKSLSVKEVKSFTQIQA
TFCISELQVQLSGDLTLGAQGLVSLKFQDFEVEFSKDHPQTLSIQIALHSLLMEDLLEKNPDSKYKNLMVSRGAPKPSSLAQKEYLSQSC
PSVSNVEYPDMPRSLPSHMEEAPNVFQLYQRPTSASRKKQKEVQDKDYPLTPPPSPTVDEPKILVGKSKFDDSLVHINIFLVDKKHPEFS
SSYNRVNRSIDVDFNCLDVLITLQTWVVILDFFGIGSTADNHAMRLPPEGILHNVKLEPHASMESGLQDPVNTKLDLKVHSLSLVLNKTT
SELAKANVSKLVAHLEMIEGDLALQGSIGSLSLSDLTCHGEFYRERFTTSGEEALIFQTFKYGRPDPLLRREHDIRVSLRMASVQYVHTQ
RFQAEVVAFIQHFTQLQDVLGRQRAAIEGQTVRDQAQRCSRVLLDIEAGAPVLLIPESSRSNNLIVANLGKLKVKNKFLFAGFPGTFSLQ
DKESVPSASPTGIPKHSLRKTTSTEEPRGTHSQGQFTMPLAGMSLGSLKSEFVPSTSTKQQGPQPTLSVGQESSSPEDHVCLLDCVVVDL
QDMDIFAAERHPREYSKAPEDSSGDLIFPSYFVRQTGGSLLTEPCRLKLQVERNLDKEISHTVPDISIHGNLSSVHCSLDLYKYKLIRGL
LENNLGEPIEEFMRPYDLQDPRIHTVLSGEVYTCMCFLIDMVNVSLELKDPKRKEGAGSLARFDFKKCKLLYESFSNQTKSINLVSHSMM
AFDTRYAGQKTSPGMTNVFSCIFQPAKNSSTTQGSIQIELHFRSTKDSSCFTVVLNNLRVFLIFDWLLLVHDFLHTPSDIKKQNHVTPSR
HRNSSSESAIVPKTVKSGVVTKRSSLPVSNERHLEVKVNVTGTEFVVIEDVSCFDTNAIILKGTTVLTYKPRFVDRPFSGSLFGIEVFSC
RLGNEHDTALSIVDPVQIQMELVGNSSYQNSSGLMDAFNSEDFPPVLEIQLQALDIRLSYNDVQLFLAIAKSIPEQANAAVPDSVALESD
SVGTYLPGASRVGEEIREGTRHTLDPVLELQLARLQELGFSMDDCRKALLACQGQLKKAASWLFKNAEPLKSLSLASTSRDSPGAVAAPL
ISGVEIKAESVCICFIDDCMDCDVPLAELTFSRLNFLQRVRTSPEGYAHFTLSGDYYNRALSGWEPFIEPWPCSVSWQQQAASRLHPPRL
KLEAKAKPRLDINITSVLIDQYVSTKESWMADYCKDDKDIESAKSEDWMGSSVDPPCFGQTEVKTPKRRQPFVPFALRNHTGCTLWFATL
TTTPTRAALSHSGSPGVVPEGNGTFLDDTHNVSEWREVLTGEEIPFEFEARGKLRHRHTHDLRIHQLQVRVNGWEQVSPVSVDKVGTFFR
YAAPDKNSSSSTIGSPSSRTNIIHPQVYFSSLPPVRVVFAVTMEGSARKVITVRSALIVRNRLETPMELRLDSPSAPDKPVVLPAIMPGD
SFAVPLHLTSWRLQARPKGLGVFFCKAPIHWTNVVKTAEISSSKRECHSMDTEKSRFFRFCVAIKKENYPDYMPSNIFSDSAKQIFRQPG
HTIYLLPTVVICNLLPCELDFYVKGMPINGTLKPGKEAALHTADTSQNIELGVSLENFPLCKELLIPPGTQNYMVRMRLYDVNRRQLNLT
IRIVCRAEGSLKIFISAPYWLINKTGLPLIFRQDNAKTDAAGQFEEHELARSLSPLLFCYADKEQPNLCTMRIGRGIHPEGMPGWCQGFS
LDGGSGVRALKVIQQGNRPGLIYNIGIDVKKGRGRYIDTCMVIFAPRYLLDNKSSHKLAFAQREFARGQGTANPEGYISTLPGSSVVFHW
PRNDYDQLLCVRLMDVPNCIWSGGFEVNKNNSFHINMRDTLGKCFFLRVEITLRGATYRISFSDTDQLPPPFRIDNFSKVPVVFTQHGVA
EPRLRTEVKPMTSLDYAWDEPTLPPFITLTVKGAGSSEINCNMNDFQDNRQLYYENFIYIAATYTFSGLQEGTGRPVASNKAITCAELVL
DVSPKTQRVILKKKEPGKRSQLWRMTGTGMLAHEGSSVPHNPNKPSAARSTEGSAILDIAGLAAVTDNRYEPLMLRKPDRRRSTTQTWSF
REGKLTCGLHGLVVQAKGGLSGLFDGAEVVLGPDTSMELLGPVPPEQQFINQKMRPGSGMLSIRVIPDGPTRALQITDFCHRKSSRSYEV
DELPVTEQELQKLKNPDTEQELEVLVRLEGGIGLSLINKVPEELVFASLTGINVHYTQLATSHMLELSIQDVQVDNQLIGTTQPFMLYVT
PLSNENEVIETGPAVQVNAVKFPSKSALTNIYKHLMITAQRFTVQIEEKLLLKLLSFFGYDQAESEVEKYDENLHEKTAEQGGTPIRYYF
ENLKISIPQIKLSVFTSNKLPLDLKALKSTLGFPLIRFEDAVINLDPFTRVHPYETKEFIINDILKHFQEFLGNPMGLLNDVSEGVTGLI

--------------------------------------------------------------
>98331_98331_4_VPS13D-PITPNB_VPS13D_chr1_12476754_ENST00000358136_PITPNB_chr22_28254502_ENST00000320996_length(transcript)=14538nt_BP=12421nt
GGAGGAAACGCCGCGCAGCGCCGGGCTGGGGCGGGCGGCCCGGGACACCGACAGATTTTTCTGTGACCATGAAAGAGAGAAATAAAGAAT
GATCCATGATTTCTAAACACCTTTTCCTGAGGATATAGTCATGTTGGAAGGCCTTGTAGCCTGGGTTCTCAATACCTATTTGGGAAAATA
TGTCAATAACCTGAACACTGACCAGCTCTCAGTTGCACTTCTCAAAGGTGCTGTTGAATTAGAAAACTTGCCATTAAAGAAAGATGCCTT
GAAAGAATTGGAATTACCATTTGAAGTCAAAGCTGGCTTCATTGGGAAAGTAACCCTTCAGATTCCCTTTTATCGCCCCCATGTGGACCC
TTGGGTGATCTCCATCTCCAGCCTTCACTTAATTGGAGCCCCAGAGAAAATACAGGATTTCAATGATGAAAAGGAGAAGCTGTTGGAAAG
GGAACGTAAGAAAGCACTACTTCAAGCCCTGGAGGAGAAATGGAAGAATGACCGCCAGCAGAAAGGGGAGTCCTATTGGTATTCAGTTAC
CGCCTCCGTAGTTACAAGGATTGTGGAGAATATTGAATTAAAAATTCAAGATGTCCATTTACGCTTTGAAGATGGTGTCACCAATCCCTC
CCATCCTTTTGCTTTTGGCATCTGCATTAAGAATGTGTCCATGCAAAATGCTGTGAATGAGCCTGTACAGAAACTAATGCGGAAAAAGCA
ATTAGACGTAGCAGAATTTAGCATCTATTGGGATGTCGATTGCACTTTACTGGGGGATTTGCCTCAGATGGAGTTACAGGAGGCCATGGC
CAGGAGCATGGAGAGTCGCAGCCATCACTACGTCCTGGAGCCTGTGTTTGCATCTGCTCTTTTGAAGAGAAACTGCTCCAAGAAGCCCCT
GCGGTCTCGGCACAGTCCCCGTATTGATTGTGATATTCAGCTGGAGACCATTCCCTTGAAACTCTCTCAGCTGCAATACCGGCAAATCAT
GGAATTCCTCAAGGAGCTGGAACGAAAGGAGAGGCAGGTGAAGTTCCGAAGGTGGAAACCCAAGGTGGCGATATCTAAGAACTGCCGAGA
ATGGTGGTATTTTGCTTTGAATGCTAACTTGTATGAGATCAGAGAGCAGAGGAAACGTTGCACCTGGGACTTTATGTTGCACCGCGCTCG
TGATGCTGTATCTTACACTGACAAATATTTCAACAAGTTAAAAGGAGGCCTGCTGTCCACAGATGACAAGGAGGAAATGTGTCGGATTGA
AGAGGAACAGAGCTTTGAGGAATTGAAGATTTTGCGTGAACTGGTTCATGATCGATTTCACAAACAGGAAGAACTAGCAGAGAGTCTGCG
GGAGCCTCAGTTTGATTCTCCAGGAGCCTGTCCGGGAGCCCCAGAACCCGGTGGAGGCAGTGGGATGCTGCAGTATCTCCAGTCCTGGTT
TCCTGGATGGGGTGGCTGGTACGGGCAGCAGACCCCAGAAGGGAATGTGGTTGAGGGACTGTCAGCAGAGCAACAGGAGCAGTGGATTCC
TGAAGAGATCCTGGGCACTGAGGAGTTTTTTGACCCCACTGCAGATGCCTCGTGTATGAACACGTATACAAAGCGAGATCATGTCTTTGC
CAAACTGAATTTGCAGTTGCAGCGAGGTACAGTGACTCTGTTACACAAGGAGCAAGGAACTCCTCAAATGAATGAAAGTGCTTTCATGCA
GCTCGAGTTTTCAGATGTAAAACTTCTAGCAGAGTCTCTTCCTCGAAGAAATTCCTCGTTGCTTTCAGTCCGGTTGGGTGGACTGTTTCT
TCGAGACCTGGCTACAGAAGGAACTATGTTTCCTCTTCTAGTCTTCCCTAATCCACAAAAAGAAGTTGGCAGAGTCTCACAATCTTTTGG
TCTACAAACTACATCTGCAGACAGAAGTGATCATTACCCAGCTGCAGATCCAGATGGCCCCGTTTTTGAGATGCTGTATGAGAGAAATCC
GGCGCACAGCCACTTTGAGAGGCGGCTCAATGTCAGCACAAGGCCCTTGAACATCATATACAATCCGCAGGCCATTAAAAAAGTAGCAGA
CTTTTTCTACAAGGGAAAGGTTCATACCTCAGGTTTTGGTTATCAGTCTGAACTTGAGCTGAGAGTGGCTGAAGCTGCCCGAAGACAATA
TAACAAGCTGAAGATGCAGACCAAGGCAGAAATCCGGCAAACTCTTGATCGTTTGCTAGTGGGTGATTTCATTGAGGAGAGTAAACGATG
GACCGTGCGGCTGGATATTTCTGCCCCTCAGGTGATATTTCCTGATGATTTCAAATTCAAGAATCCTGTGTTAGTTGTCGTGGATCTAGG
AAGAATGCTTTTGACGAACACCCAAGATAACTCCAGGAGGAAAAGTAGGGATGGGTCAGCATCTGAAGAGACCCAGTTTAGTGATGATGA
ATATAAGACCCCCCTGGCCACACCTCCTAACACCCCACCTCCCGAGTCAAGCAGCAGCAACGGAGAGAAAACACCTCCCTTTTCTGGAGT
TGAGTTCAGTGAAGAACAGCTTCAAGCACATTTAATGAGCACAAAGATGTATGAGAGGTACTCGCTGTCATTTATGGACCTCCAGATCAT
GGTTGGACGAGTGAAAGACAATTGGAAGCATGTCCAGGATATTGACGTGGGACCAACACATGTGGTAGAGAAGTTCAACGTTCACCTACA
GTTAGAGCGTCGATTGATTTATACTTCAGATCCCAAATATCCAGGAGCCGTGCTCTCAGGCAACTTACCAGACTTAAAAATCCACATTAA
TGAAGATAAAATATCTGCACTAAAGAATTGCTTTGCTCTCCTCACCACCCCAGAAATGAAAACTTCTGACACTCAGATTAAAGAAAAGAT
TTTTCCCCAGGAGGAGCAGCGGGGAAGTTTGCAAGACTCCGTAATGAATTTAACCCAGAGCATTGTGTTGTTGGAGCAGCATACCCGCGA
GGTTCTGGTGGAGTCGCAGCTCCTCCTGGCGGAATTTAAAGTGAACTGTATGCAGCTTGGTGTTGAGAGCAATGGCCGGTACATTTCTGT
GCTCAAGGTGTTTGGTACCAATGCTCACTTTGTGAAGAGGCCTTATGATGCTGAAGTCTCCCTAACTGTTCATGGTTTGCTCCTGGTGGA
TACCATGCAGACATATGGTGCTGATTTTGACCTTTTGATGGCTTCACATAAGAACTTGAGCTTTGATATTCCAACGGGAAGCCTTCGGGA
TAGCAGGGCCCAGTCTCCTGTCTCTGGACCGAATGTGGCCCACTTAACTGATGGAGCTACACTGAACGACCGATCAGCTACTAGTGTTTC
ACTTGACAAAATTCTTACCAAAGAGCAAGAGTCCCTTATTAAGTTGGAATATCAGTTTGTGAGTTCAGAGTGCCCATCGATGAATTTAGA
CAGTACTCTTCAGGTGATTTCCCTACAGGTGAATAATTTAGATATTATCCTCAATCCAGAGACGATTGTGGAGCTAATTGGTTTTCTTCA
AAAATCCTTTCCCAAGGAAAAAGATGATTTAAGTCCTCAACCTTTAATGACTGATTTTGAAAGAAGCTTCAGAGAACAAGGAACTTACCA
GTCTACATATGAACAAAACACTGAGGTTGCAGTGGAAATCCATAGGCTGAACTTACTGCTTCTTCGGACAGTGGGCATGGCAAATAGAGA
GAAATATGGCAGAAAAATTGCAACTGCAAGTATAGGTGGCACCAAAGTTAATGTCTCAATGGGTAGCACGTTTGACATGAATGGTTCTCT
TGGCTGTTTACAGCTTATGGATTTGACACAAGATAACGTTAAAAACCAGTATGTTGTCAGCATTGGGAATTCTGTAGGCTATGAAAATAT
CATCAGTGATATTGGCTACTTTGAATCTGTGTTTGTCAGAATGGAAGATGCAGCCCTCACTGAAGCTTTGAGTTTCACGTTTGTTGAGAG
ATCTAAACAGGAGTGTTTTCTCAACCTGAAGATGGCTTCTTTACATTATAACCACTCTGCTAAGTTTTTGAAGGAGTTGACGTTATCCAT
GGATGAACTGGAAGAAAATTTTCGAGGTATGCTGAAAAGCGCAGCCACCAAAGTCACCACAGTACTAGCTACCAAGACTGCCGAGTATAG
CGAGATGGTATCGCTCTTTGAAACTCCAAGGAAGACTCGGGAACCCTTTATCTTAGAGGAAAATGAAATATATGGGTTTGACCTAGCTTC
GTCTCATTTGGACACTGTAAAGCTAATCTTGAACATAAACATTGAATCACCAGTTGTTTCTATCCCTCGGAAGCCGGGGAGTCCTGAGTT
GTTGGTGGGACACTTGGGACAGATATTCATCCAGAATTTTGTGGCGGGAGATGATGAATCCAGAAGTGACCGTCTGCAGGTGGAAATCAA
GGACATTAAACTGTATTCTTTGAATTGCACCCAGTTGGCAGGTAGAGAAGCTGTTGGGTCTGAAGGAAGCCGGATGTTTTGCCCACCTTC
CGGGTCTGGCAGTGCCAACAGTCAGGAGGAAGCTCATTTCACACGACATGATTTCTTTGAATCTTTGCATAGAGGTCAAGCTTTTCACAT
CCTGAACAACACCACCATTCAGTTTAAACTGGAGAAGATCCCTATAGAGAGAGAATCTGAATTGACTTTTTCTCTTAGCCCAGATGACCT
GGGAACTTCTAGCATCATGAAGATTGAAGGAAAATTTGTCAATCCAGTTCAGGTGGTGTTAGCAAAGCATGTATATGAGCAGGTTTTACA
AACCCTGGACAATCTCGTGTACAGTGAAGATCTGAATAAGTATCCAGCCAGTGCTACCTCCTCCCCTTGCCCTGATTCTCCTCTGCCTCC
CCTCAGTACCTGTGGAGAATCTTCTGTTGAAAGGAAGGAGAATGGATTGTTCAGCCACTCCAGCCTTTCTAACACCTCTCAGAAGTCATT
GTCAGTGAAGGAAGTCAAATCCTTTACTCAGATTCAAGCCACCTTTTGTATATCAGAGCTTCAGGTTCAGCTAAGTGGAGATCTGACTTT
GGGGGCCCAAGGTCTTGTGAGCTTAAAGTTTCAGGACTTTGAGGTGGAATTCAGTAAAGACCATCCCCAGACTTTATCTATTCAGATTGC
CCTGCATTCTCTGCTGATGGAGGACTTATTGGAGAAGAATCCAGATTCTAAATATAAGAACCTGATGGTGTCTCGAGGAGCCCCTAAGCC
ATCTAGTTTAGCACAAAAAGAATACCTTTCTCAGTCTTGCCCCTCAGTGTCCAATGTGGAATATCCTGATATGCCTCGGTCTCTCCCTTC
CCACATGGAAGAAGCTCCTAATGTCTTCCAGTTGTATCAAAGGCCCACCTCTGCGTCCCGGAAAAAGCAAAAGGAAGTCCAAGACAAGGA
CTATCCCTTGACCCCACCTCCTTCTCCAACAGTGGATGAGCCCAAGATACTTGTTGGAAAGAGTAAATTTGATGATTCCTTAGTCCACAT
CAACATATTCTTGGTAGATAAGAAACATCCAGAATTCTCTTCCAGTTACAATCGAGTTAACCGGAGCATTGATGTTGATTTTAATTGCTT
GGATGTGCTGATCACACTGCAAACCTGGGTTGTGATATTAGACTTTTTTGGAATCGGCTCCACTGCAGACAACCACGCAATGAGGCTGCC
TCCTGAGGGCATTCTGCACAACGTGAAGTTGGAGCCACATGCCTCCATGGAGTCTGGACTTCAGGATCCAGTGAACACCAAACTGGATCT
CAAGGTTCATTCACTTTCTCTAGTGCTGAATAAGACCACCAGTGAGCTTGCCAAAGCAAATGTGTCCAAATTAGTAGCACACCTGGAAAT
GATTGAGGGAGACCTGGCCTTACAGGGCAGCATTGGGAGTCTGTCTCTAAGTGACCTCACATGCCATGGAGAGTTCTACAGAGAACGGTT
CACTACCAGTGGTGAAGAAGCACTCATCTTCCAGACTTTTAAATACGGACGGCCTGACCCTCTGCTCCGGAGAGAACACGACATTCGCGT
GAGCCTCCGGATGGCCTCTGTGCAGTATGTGCATACTCAGCGTTTCCAGGCAGAGGTGGTGGCCTTCATTCAGCATTTCACTCAGCTGCA
GGATGTCTTAGGGCGCCAGCGAGCTGCTATTGAGGGGCAGACGGTGAGAGATCAAGCCCAGCGCTGTTCACGGGTTCTCCTGGATATTGA
GGCTGGTGCTCCCGTTCTCTTGATCCCAGAAAGTTCCAGATCAAATAATCTGATTGTAGCAAATTTGGGGAAGTTGAAAGTCAAAAATAA
GTTTCTGTTTGCTGGTTTTCCTGGCACCTTTTCCCTACAAGATAAGGAATCTGTGCCTTCAGCTTCCCCAACGGGTATTCCCAAACACAG
TCTGAGGAAAACGACAAGCACGGAGGAGCCCAGGGGAACCCATTCCCAGGGGCAGTTCACGATGCCTCTTGCTGGAATGAGCCTAGGAAG
CCTGAAGAGTGAGTTTGTGCCCAGTACCTCCACCAAGCAGCAAGGGCCGCAACCCACACTGTCTGTTGGCCAAGAGTCCAGTAGTCCAGA
AGACCATGTCTGCCTGCTGGATTGCGTTGTCGTGGATCTCCAGGACATGGACATCTTTGCTGCAGAGAGACATCCGAGAGAATACTCGAA
GGCACCAGAGGATAGTAGTGGAGATCTGATCTTCCCTTCCTATTTTGTGCGACAGACAGGAGGAAGCCTCTTAACCGAGCCTTGTAGGCT
GAAATTGCAGGTGGAAAGGAATTTGGACAAAGAAATAAGTCATACTGTGCCAGACATATCTATCCATGGCAATCTCTCCTCAGTCCACTG
CTCTCTGGATCTGTATAAATACAAGCTGATCCGCGGCTTATTAGAGAACAACCTGGGAGAACCCATAGAGGAATTTATGCGGCCTTATGA
TTTACAAGATCCAAGAATTCATACTGTCCTGAGTGGAGAAGTGTACACCTGTATGTGCTTCCTCATTGATATGGTGAATGTAAGTCTGGA
GCTTAAAGATCCAAAAAGAAAAGAAGGTGCTGGGTCCCTAGCCAGATTTGACTTCAAGAAATGCAAACTGCTCTATGAAAGTTTTTCCAA
CCAAACCAAGTCCATTAACTTGGTTTCCCATTCCATGATGGCTTTTGACACCCGTTATGCTGGGCAGAAGACCAGCCCTGGCATGACGAA
TGTGTTCAGCTGTATCTTTCAGCCCGCTAAGAACAGCAGCACCACCCAAGGGTCCATTCAGATTGAACTACATTTCAGATCTACCAAGGA
TTCCTCCTGCTTTACAGTAGTTCTCAACAATCTCCGTGTGTTTCTCATATTTGACTGGCTACTGTTAGTCCATGATTTTCTCCACACTCC
CAGTGATATTAAGAAACAAAATCATGTTACTCCTTCTCGCCACCGTAACTCTAGCAGCGAATCTGCTATAGTTCCCAAAACTGTGAAGAG
TGGAGTAGTTACCAAGCGGTCTTCCCTTCCTGTGTCCAATGAAAGGCACCTGGAGGTCAAGGTCAATGTAACAGGTACGGAGTTTGTGGT
CATTGAAGATGTGTCCTGCTTCGACACCAATGCCATTATTCTGAAAGGCACCACAGTGCTCACCTATAAGCCCCGGTTTGTTGATCGCCC
CTTTTCAGGAAGTTTGTTTGGCATTGAGGTGTTTTCATGCCGACTAGGGAATGAGCATGATACAGCTCTTTCAATTGTGGATCCCGTACA
AATTCAAATGGAGTTGGTGGGGAATTCTTCTTATCAAAATAGTTCAGGATTGATGGATGCATTCAATAGTGAAGATTTCCCACCTGTCCT
GGAGATTCAGTTACAAGCCCTGGATATCAGACTCTCCTATAATGATGTTCAGCTGTTTCTTGCCATTGCAAAATCCATCCCAGAGCAAGC
TAATGCTGCAGTGCCAGACTCAGTGGCCCTGGAGTCAGACTCCGTTGGCACTTACCTTCCAGGTGCATCTCGCGTTGGAGAGGAAATCAG
AGAAGGGACAAGACACACCTTAGATCCTGTCTTGGAGTTACAGCTGGCTAGGCTGCAGGAGCTGGGATTCAGCATGGATGATTGTCGCAA
AGCTCTTTTGGCGTGTCAAGGCCAATTGAAAAAGGCAGCAAGTTGGTTGTTTAAGAATGCGGAACCTCTGAAGTCTCTTTCCTTGGCCTC
CACCAGCCGAGATAGCCCAGGGGCTGTGGCAGCGCCATTGATCTCTGGCGTGGAGATCAAAGCTGAGAGTGTGTGCATCTGTTTCATCGA
TGACTGCATGGATTGTGATGTTCCTCTCGCTGAACTCACCTTTTCCCGTCTGAATTTTCTTCAGCGTGTAAGAACTAGCCCTGAAGGCTA
TGCCCACTTCACCCTTTCTGGAGATTATTATAACCGTGCTCTTTCAGGCTGGGAGCCATTTATTGAGCCTTGGCCATGCTCTGTATCCTG
GCAACAGCAGGCAGCTAGTCGTCTCCATCCTCCTCGACTGAAGCTAGAAGCCAAGGCCAAACCTCGTTTGGATATCAATATCACTTCTGT
GCTAATTGACCAGTATGTAAGTACCAAGGAATCGTGGATGGCAGATTACTGTAAAGATGACAAGGACATAGAGTCAGCTAAATCAGAAGA
CTGGATGGGCTCTTCGGTGGATCCTCCATGTTTTGGACAAAGCCTCCCCCTTGTCTACCTTAGAACTAGGAGTACAGCCAGTCTGACTAA
CCTAGAGCACCAGATCTATGCTAGAGCAGAGGTGAAAACCCCCAAGCGCCGGCAGCCATTTGTCCCCTTTGCTCTGAGGAACCACACGGG
GTGCACTTTGTGGTTTGCCACCCTGACCACCACACCCACCAGAGCTGCACTCTCTCACAGTGGGAGTCCAGGGGTAGTTCCAGAAGGGAA
CGGAACATTTCTCGATGATACTCACAATGTTAGTGAATGGCGAGAAGTCCTTACAGGTGAAGAGATTCCCTTTGAATTTGAAGCAAGAGG
AAAGTTAAGACACAGACACACCCATGACCTCCGGATTCATCAACTGCAAGTGAGAGTAAATGGCTGGGAGCAAGTGAGCCCAGTGTCTGT
GGACAAAGTCGGGACCTTTTTTCGATATGCAGCACCAGATAAAAATTCATCTTCCTCTACGATTGGCAGCCCAAGCAGCAGAACAAATAT
TATACATCCCCAGGTTTATTTCTCTTCACTCCCACCAGTGCGGGTGGTCTTTGCAGTGACTATGGAAGGCAGTGCACGGAAAGTCATCAC
TGTCCGGTCAGCCCTCATTGTGAGGAACAGACTTGAGACACCAATGGAACTAAGACTGGATAGCCCATCAGCTCCAGACAAGCCAGTGGT
GCTTCCTGCTATCATGCCAGGGGATTCGTTTGCTGTGCCTTTACACCTCACTTCTTGGCGGCTACAGGCCCGGCCCAAAGGATTGGGTGT
ATTTTTCTGTAAGGCTCCCATTCATTGGACCAATGTAGTGAAGACTGCAGAAATTAGTAGCAGTAAACGAGAGTGCCACTCTATGGACAC
AGAAAAAAGCCGATTTTTCAGGTTTTGTGTGGCTATAAAGAAAGAGAATTATCCAGATTATATGCCCTCAAACATATTTTCTGACAGTGC
AAAACAGATTTTCAGACAGCCTGGGCATACCATATATCTCCTGCCAACTGTGGTAATCTGCAACTTGCTACCCTGTGAACTTGATTTTTA
TGTTAAAGGAATGCCAATTAATGGGACGCTGAAACCTGGCAAGGAGGCAGCTCTCCATACAGCTGATACATCCCAGAACATTGAGCTGGG
GGTATCACTGGAGAATTTCCCCCTCTGTAAAGAATTGCTCATTCCACCTGGAACCCAAAACTATATGGTGAGAATGCGACTCTATGACGT
CAACCGTCGGCAGCTGAACCTCACCATCCGGATTGTGTGTCGAGCAGAAGGATCCTTAAAGATCTTCATTTCTGCTCCATATTGGCTGAT
TAACAAAACAGGGTTGCCACTGATCTTCAGACAGGACAATGCCAAGACAGATGCTGCAGGCCAGTTTGAGGAGCATGAGCTGGCCCGTAG
CCTGAGTCCTCTCTTATTCTGCTATGCTGACAAAGAGCAGCCAAACCTCTGCACGATGAGAATCGGAAGGGGGATTCATCCAGAAGGCAT
GCCGGGCTGGTGTCAGGGCTTCTCCCTGGATGGTGGTAGTGGTGTCCGAGCTTTGAAAGTCATCCAGCAAGGAAACCGCCCAGGGCTGAT
CTATAACATTGGTATTGATGTCAAGAAAGGCCGAGGTCGATACATTGATACCTGCATGGTCATCTTTGCCCCCCGTTACCTGTTAGATAA
TAAATCATCTCACAAGCTTGCATTTGCACAGAGGGAATTTGCCAGGGGACAGGGAACAGCCAATCCCGAAGGTTACATTTCCACCCTTCC
TGGTTCCAGTGTGGTGTTCCACTGGCCTCGGAATGACTATGATCAGCTATTGTGTGTCAGACTGATGGACGTTCCCAATTGTATTTGGTC
TGGAGGCTTTGAAGTCAACAAGAATAATTCCTTCCATATCAACATGAGGGATACCTTGGGAAAATGCTTCTTCCTACGAGTGGAAATTAC
TCTCCGAGGAGCTACGTATAGGATCTCATTTAGTGACACAGATCAGTTACCTCCTCCTTTCCGAATTGACAACTTTTCTAAGGTCCCGGT
TGTCTTTACTCAGCATGGCGTAGCTGAACCCAGGCTCCGGACTGAAGTGAAGCCCATGACTTCATTGGATTATGCCTGGGACGAACCCAC
CTTGCCACCTTTTATCACTCTGACTGTTAAAGGGGCAGGGTCCTCTGAGATCAACTGCAACATGAATGATTTCCAGGATAATCGGCAGCT
TTATTATGAAAATTTCATTTACATTGCTGCTACATATACATTCTCTGGCTTGCAGGAGGGAACAGGCAGGCCTGTGGCTTCCAACAAGGC
CATTACCTGTGCGGAGCTCGTTTTGGATGTCTCACCCAAGACACAAAGAGTCATTTTAAAAAAGAAGGAACCAGGAAAGCGTTCTCAGCT
GTGGAGGATGACAGGAACAGGAATGCTGGCCCATGAGGGCTCCTCAGTTCCTCACAATCCCAATAAGCCCTCAGCCGCCCGCTCCACCGA
GGGGTCTGCCATCTTAGATATTGCTGGTCTCGCTGCAGTGACTGACAACAGATACGAGCCACTGATGCTGAGAAAGCCTGACCGCAGGCG
AAGCACAACTCAGACGTGGAGTTTCCGAGAAGGAAAACTGACCTGTGGGTTACATGGGTTGGTCGTCCAGGCCAAAGGAGGACTTTCTGG
TTTGTTTGATGGAGCTGAAGTTGTTCTTGGTCCTGACACTTCCATGGAGCTTTTGGGGCCAGTTCCACCTGAACAACAATTTATTAATCA
AAAAATGAGACCTGGTTCTGGAATGTTATCCATCAGAGTCATCCCAGATGGACCAACTAGAGCACTCCAGATAACAGATTTCTGCCACCG
GAAAAGCAGCCGTTCATATGAAGTGGATGAACTTCCTGTCACCGAACAAGAGCTGCAGAAATTAAAGAATCCAGATACAGAGCAGGAATT
GGAAGTGCTTGTGAGGTTAGAAGGTGGAATTGGGTTGTCCTTAATTAATAAAGTCCCAGAAGAACTGGTCTTTGCAAGTCTTACAGGAAT
CAATGTGCACTATACACAGCTGGCAACCAGTCACATGCTTGAACTCAGCATACAGGATGTACAGGTGGACAATCAGCTCATTGGTACCAC
GCAGCCCTTCATGCTCTATGTGACTCCCCTGAGCAATGAGAATGAGGTCATCGAGACCGGCCCAGCTGTGCAAGTCAACGCAGTGAAGTT
CCCCAGTAAGAGTGCACTGACCAACATCTACAAGCATCTGATGATCACAGCTCAGAGATTCACAGTGCAAATTGAGGAGAAACTGCTCCT
CAAGCTGCTAAGTTTCTTTGGCTACGATCAAGCAGAATCAGAGGTGGAAAAATATGATGAAAACCTCCATGAAAAGACAGCTGAGCAAGG
TGGAACACCAATTCGATACTACTTTGAAAATCTCAAAATCAGCATTCCTCAGATCAAGCTAAGTGTGTTCACCTCCAACAAGCTCCCATT
GGATCTTAAGGCCCTAAAAAGCACCTTGGGGTTTCCTTTGATACGGTTTGAAGACGCTGTGATTAATCTAGATCCATTCACTCGGGTACA
TCCCTATGAGACCAAGGAGTTCATCATCAATGATATCCTCAAACATTTCCAGGAGTTTCTTGGCAATCCTATGGGGCTTTTGAATGATGT
TTCTGAAGGGGTTACTGGACTGATAAAATATGGAAATGTCGGGGGCCTCATCAGAAATGTTACACACGGAGTATCAAACTCTGCTGCCAA
GCAAGAAAAACGGATATTTACAAACTTCCATCGCCAGCTTTTTTGTTGGATTGACAAGTGGATCGATCTCACGATGGAAGACATTAGGAG
AATGGAAGACGAGACTCAGAAAGAACTAGAAACATTACGTAATCAAGGTCAAGTGAGGGGAACAAGCGCAGCCAGTGATGAGTGAAGAAG
AATCTGACCAGTATCTTGCAGTGTTGACGTTTCCCAGATGTGTGCTTGTGATGATACACACACATGCACAGGTTCTCAACCACGTGTGTA
TATATGTATGTGTGCATATGTCTGTAGCTGTATATAAAGCGCATGTAGAGCTACAGATCCAGATACACACACTTGTGTATATATGTACAT
ACAGACATACTGAAGGGATTAGTACAATTTCTCCAAAGTACTGTACCTATCTTCAGCAAGAATGCAAAAGAAAATATTTTCAATATATAT
ACCTGGAACAGATTTTAATAATTATCAGAGTAATACCATTAATGGACAAATTGACTGCAATGTAATACTAGCTGGTATGTTTCATAAATG
TCAAGCTGTGGACCAACATATATAGCCTTTTATTATTTTTCTCTTCTTTTAAGTCAGTCTGTTATAAATTTTTTTTTAGTCCCATAAGCA
GTAGACTCCCACAGAAAATTTCTTCAAAATTTTTTGGTGTTCCAATGAATCTGGGATGTAAACTCTGAATGTATTTATAACTATTTATTT
CTGGATGGTCATTATCTTGTAGCCAAATTTGACAATATAAAGTAAGGAGCAAAGTTACAGGCCAGTTTTTACTTGTTTGCCCTGAGGGAA
AAATCCTTTTAAAAAAAATTTCTGGTTTTTATTGGATTTTTGTATTTTAAATTTCAAATATTTTTCTACATCAAACCTAGCAAAAATGGA
GATGACGGTTTCTGATTTATAATAAATACTAGACAGTTTTCAGGCTCCTGTTAGACAAACACATTGATGAAGAAATTAGTCTTAATAGGA
TTGTAGGCTGTGTAGAAAAGTTGGAAATATAGCACTTCATGGAGTCTTGTTTTGAAGATGACAGTTTTCTGTAACTACAGCTTGGAAACT
ATGCAAATGGTCTAGATTCCTCAGAGCTCACATGATAGGATATAGTTAGTGATGACATTTTGCTCTTCTTGTGGGAACACACACTTCAAG
GAGGAGATAGTGACTTTGAGATAGGAACAGTTTAAGATGCAGTGTGAGTCTGGCCTGCGTGCGGTGAGGAGGCCCCGCCAAGAGACTGGT
GGACATCTGACTGTGGGATGTGCTCTCAAGTAGGACGTCATCAGGACAGATTCTGAATAGGCATCATGAGAGTGCTGGTCAGAAACGGCT
GCCACTTTTTTTAATTTAATTTTATTTTTTATTTAAAGGAAGGAACAATAGCTAGGTAAGATTTTTATCAGCTTTCTCTGTCTGAATCCA
GTTTTTCCTCTGTCAGTCCTGGAAGCTTGAATAGAATTATATTGTTGAAGCCTTCAGGTCACAAACTGTCTTTTGTAACCTCCTGTCCCT
CCTAAAACACGCCAACCCCTGCAGTCAAATCACATTAGTAATCTGATTTGCTGACAGTCCTGCCCTGCCTGCTCCTCGTTTTCCCACATG
TCCTGCATCCCTCCCCCACTGGAGTGATTTCAGTGAATCAGACAAGGAAGGATGTGTAGGATCACTACTGCATTGCAATACCCTGTTATC
CTCAGCAACAAAACCCACATTTCATACATCCTTTGTGTACTCAGGATAAAGACTGATGTTTACTCTCTGGGCACTGTTGTAAGATAGGTT
TTGTCAGAGCATAATCATTGTCTGCAAAGTGTTTGGTGCGAGGAAGATTATTGCTAATTTTGTGAAATAAAGAGTCTAGCCCTCTCCTTT
TAATGAACTTAACTCTCGCTGGCATCTGTAGTATCATTGGGAGCTTAGGCGCACATGGAAATGAGAGCCCGGCGCATGGATTTTAATGTT
TTTCTAACAACTGTGGAGATTTGAGGGAATGTGTGGTGAATGTAAAATACCTAGTTTACTTGCCAGTCTCTTGTGTAAATTACAGTAAAA

>98331_98331_4_VPS13D-PITPNB_VPS13D_chr1_12476754_ENST00000358136_PITPNB_chr22_28254502_ENST00000320996_length(amino acids)=4154AA_BP=4096
MLEGLVAWVLNTYLGKYVNNLNTDQLSVALLKGAVELENLPLKKDALKELELPFEVKAGFIGKVTLQIPFYRPHVDPWVISISSLHLIGA
PEKIQDFNDEKEKLLERERKKALLQALEEKWKNDRQQKGESYWYSVTASVVTRIVENIELKIQDVHLRFEDGVTNPSHPFAFGICIKNVS
MQNAVNEPVQKLMRKKQLDVAEFSIYWDVDCTLLGDLPQMELQEAMARSMESRSHHYVLEPVFASALLKRNCSKKPLRSRHSPRIDCDIQ
LETIPLKLSQLQYRQIMEFLKELERKERQVKFRRWKPKVAISKNCREWWYFALNANLYEIREQRKRCTWDFMLHRARDAVSYTDKYFNKL
KGGLLSTDDKEEMCRIEEEQSFEELKILRELVHDRFHKQEELAESLREPQFDSPGACPGAPEPGGGSGMLQYLQSWFPGWGGWYGQQTPE
GNVVEGLSAEQQEQWIPEEILGTEEFFDPTADASCMNTYTKRDHVFAKLNLQLQRGTVTLLHKEQGTPQMNESAFMQLEFSDVKLLAESL
PRRNSSLLSVRLGGLFLRDLATEGTMFPLLVFPNPQKEVGRVSQSFGLQTTSADRSDHYPAADPDGPVFEMLYERNPAHSHFERRLNVST
RPLNIIYNPQAIKKVADFFYKGKVHTSGFGYQSELELRVAEAARRQYNKLKMQTKAEIRQTLDRLLVGDFIEESKRWTVRLDISAPQVIF
PDDFKFKNPVLVVVDLGRMLLTNTQDNSRRKSRDGSASEETQFSDDEYKTPLATPPNTPPPESSSSNGEKTPPFSGVEFSEEQLQAHLMS
TKMYERYSLSFMDLQIMVGRVKDNWKHVQDIDVGPTHVVEKFNVHLQLERRLIYTSDPKYPGAVLSGNLPDLKIHINEDKISALKNCFAL
LTTPEMKTSDTQIKEKIFPQEEQRGSLQDSVMNLTQSIVLLEQHTREVLVESQLLLAEFKVNCMQLGVESNGRYISVLKVFGTNAHFVKR
PYDAEVSLTVHGLLLVDTMQTYGADFDLLMASHKNLSFDIPTGSLRDSRAQSPVSGPNVAHLTDGATLNDRSATSVSLDKILTKEQESLI
KLEYQFVSSECPSMNLDSTLQVISLQVNNLDIILNPETIVELIGFLQKSFPKEKDDLSPQPLMTDFERSFREQGTYQSTYEQNTEVAVEI
HRLNLLLLRTVGMANREKYGRKIATASIGGTKVNVSMGSTFDMNGSLGCLQLMDLTQDNVKNQYVVSIGNSVGYENIISDIGYFESVFVR
MEDAALTEALSFTFVERSKQECFLNLKMASLHYNHSAKFLKELTLSMDELEENFRGMLKSAATKVTTVLATKTAEYSEMVSLFETPRKTR
EPFILEENEIYGFDLASSHLDTVKLILNINIESPVVSIPRKPGSPELLVGHLGQIFIQNFVAGDDESRSDRLQVEIKDIKLYSLNCTQLA
GREAVGSEGSRMFCPPSGSGSANSQEEAHFTRHDFFESLHRGQAFHILNNTTIQFKLEKIPIERESELTFSLSPDDLGTSSIMKIEGKFV
NPVQVVLAKHVYEQVLQTLDNLVYSEDLNKYPASATSSPCPDSPLPPLSTCGESSVERKENGLFSHSSLSNTSQKSLSVKEVKSFTQIQA
TFCISELQVQLSGDLTLGAQGLVSLKFQDFEVEFSKDHPQTLSIQIALHSLLMEDLLEKNPDSKYKNLMVSRGAPKPSSLAQKEYLSQSC
PSVSNVEYPDMPRSLPSHMEEAPNVFQLYQRPTSASRKKQKEVQDKDYPLTPPPSPTVDEPKILVGKSKFDDSLVHINIFLVDKKHPEFS
SSYNRVNRSIDVDFNCLDVLITLQTWVVILDFFGIGSTADNHAMRLPPEGILHNVKLEPHASMESGLQDPVNTKLDLKVHSLSLVLNKTT
SELAKANVSKLVAHLEMIEGDLALQGSIGSLSLSDLTCHGEFYRERFTTSGEEALIFQTFKYGRPDPLLRREHDIRVSLRMASVQYVHTQ
RFQAEVVAFIQHFTQLQDVLGRQRAAIEGQTVRDQAQRCSRVLLDIEAGAPVLLIPESSRSNNLIVANLGKLKVKNKFLFAGFPGTFSLQ
DKESVPSASPTGIPKHSLRKTTSTEEPRGTHSQGQFTMPLAGMSLGSLKSEFVPSTSTKQQGPQPTLSVGQESSSPEDHVCLLDCVVVDL
QDMDIFAAERHPREYSKAPEDSSGDLIFPSYFVRQTGGSLLTEPCRLKLQVERNLDKEISHTVPDISIHGNLSSVHCSLDLYKYKLIRGL
LENNLGEPIEEFMRPYDLQDPRIHTVLSGEVYTCMCFLIDMVNVSLELKDPKRKEGAGSLARFDFKKCKLLYESFSNQTKSINLVSHSMM
AFDTRYAGQKTSPGMTNVFSCIFQPAKNSSTTQGSIQIELHFRSTKDSSCFTVVLNNLRVFLIFDWLLLVHDFLHTPSDIKKQNHVTPSR
HRNSSSESAIVPKTVKSGVVTKRSSLPVSNERHLEVKVNVTGTEFVVIEDVSCFDTNAIILKGTTVLTYKPRFVDRPFSGSLFGIEVFSC
RLGNEHDTALSIVDPVQIQMELVGNSSYQNSSGLMDAFNSEDFPPVLEIQLQALDIRLSYNDVQLFLAIAKSIPEQANAAVPDSVALESD
SVGTYLPGASRVGEEIREGTRHTLDPVLELQLARLQELGFSMDDCRKALLACQGQLKKAASWLFKNAEPLKSLSLASTSRDSPGAVAAPL
ISGVEIKAESVCICFIDDCMDCDVPLAELTFSRLNFLQRVRTSPEGYAHFTLSGDYYNRALSGWEPFIEPWPCSVSWQQQAASRLHPPRL
KLEAKAKPRLDINITSVLIDQYVSTKESWMADYCKDDKDIESAKSEDWMGSSVDPPCFGQSLPLVYLRTRSTASLTNLEHQIYARAEVKT
PKRRQPFVPFALRNHTGCTLWFATLTTTPTRAALSHSGSPGVVPEGNGTFLDDTHNVSEWREVLTGEEIPFEFEARGKLRHRHTHDLRIH
QLQVRVNGWEQVSPVSVDKVGTFFRYAAPDKNSSSSTIGSPSSRTNIIHPQVYFSSLPPVRVVFAVTMEGSARKVITVRSALIVRNRLET
PMELRLDSPSAPDKPVVLPAIMPGDSFAVPLHLTSWRLQARPKGLGVFFCKAPIHWTNVVKTAEISSSKRECHSMDTEKSRFFRFCVAIK
KENYPDYMPSNIFSDSAKQIFRQPGHTIYLLPTVVICNLLPCELDFYVKGMPINGTLKPGKEAALHTADTSQNIELGVSLENFPLCKELL
IPPGTQNYMVRMRLYDVNRRQLNLTIRIVCRAEGSLKIFISAPYWLINKTGLPLIFRQDNAKTDAAGQFEEHELARSLSPLLFCYADKEQ
PNLCTMRIGRGIHPEGMPGWCQGFSLDGGSGVRALKVIQQGNRPGLIYNIGIDVKKGRGRYIDTCMVIFAPRYLLDNKSSHKLAFAQREF
ARGQGTANPEGYISTLPGSSVVFHWPRNDYDQLLCVRLMDVPNCIWSGGFEVNKNNSFHINMRDTLGKCFFLRVEITLRGATYRISFSDT
DQLPPPFRIDNFSKVPVVFTQHGVAEPRLRTEVKPMTSLDYAWDEPTLPPFITLTVKGAGSSEINCNMNDFQDNRQLYYENFIYIAATYT
FSGLQEGTGRPVASNKAITCAELVLDVSPKTQRVILKKKEPGKRSQLWRMTGTGMLAHEGSSVPHNPNKPSAARSTEGSAILDIAGLAAV
TDNRYEPLMLRKPDRRRSTTQTWSFREGKLTCGLHGLVVQAKGGLSGLFDGAEVVLGPDTSMELLGPVPPEQQFINQKMRPGSGMLSIRV
IPDGPTRALQITDFCHRKSSRSYEVDELPVTEQELQKLKNPDTEQELEVLVRLEGGIGLSLINKVPEELVFASLTGINVHYTQLATSHML
ELSIQDVQVDNQLIGTTQPFMLYVTPLSNENEVIETGPAVQVNAVKFPSKSALTNIYKHLMITAQRFTVQIEEKLLLKLLSFFGYDQAES
EVEKYDENLHEKTAEQGGTPIRYYFENLKISIPQIKLSVFTSNKLPLDLKALKSTLGFPLIRFEDAVINLDPFTRVHPYETKEFIINDIL
KHFQEFLGNPMGLLNDVSEGVTGLIKYGNVGGLIRNVTHGVSNSAAKQEKRIFTNFHRQLFCWIDKWIDLTMEDIRRMEDETQKELETLR

--------------------------------------------------------------
>98331_98331_5_VPS13D-PITPNB_VPS13D_chr1_12476754_ENST00000358136_PITPNB_chr22_28254502_ENST00000335272_length(transcript)=14625nt_BP=12421nt
GGAGGAAACGCCGCGCAGCGCCGGGCTGGGGCGGGCGGCCCGGGACACCGACAGATTTTTCTGTGACCATGAAAGAGAGAAATAAAGAAT
GATCCATGATTTCTAAACACCTTTTCCTGAGGATATAGTCATGTTGGAAGGCCTTGTAGCCTGGGTTCTCAATACCTATTTGGGAAAATA
TGTCAATAACCTGAACACTGACCAGCTCTCAGTTGCACTTCTCAAAGGTGCTGTTGAATTAGAAAACTTGCCATTAAAGAAAGATGCCTT
GAAAGAATTGGAATTACCATTTGAAGTCAAAGCTGGCTTCATTGGGAAAGTAACCCTTCAGATTCCCTTTTATCGCCCCCATGTGGACCC
TTGGGTGATCTCCATCTCCAGCCTTCACTTAATTGGAGCCCCAGAGAAAATACAGGATTTCAATGATGAAAAGGAGAAGCTGTTGGAAAG
GGAACGTAAGAAAGCACTACTTCAAGCCCTGGAGGAGAAATGGAAGAATGACCGCCAGCAGAAAGGGGAGTCCTATTGGTATTCAGTTAC
CGCCTCCGTAGTTACAAGGATTGTGGAGAATATTGAATTAAAAATTCAAGATGTCCATTTACGCTTTGAAGATGGTGTCACCAATCCCTC
CCATCCTTTTGCTTTTGGCATCTGCATTAAGAATGTGTCCATGCAAAATGCTGTGAATGAGCCTGTACAGAAACTAATGCGGAAAAAGCA
ATTAGACGTAGCAGAATTTAGCATCTATTGGGATGTCGATTGCACTTTACTGGGGGATTTGCCTCAGATGGAGTTACAGGAGGCCATGGC
CAGGAGCATGGAGAGTCGCAGCCATCACTACGTCCTGGAGCCTGTGTTTGCATCTGCTCTTTTGAAGAGAAACTGCTCCAAGAAGCCCCT
GCGGTCTCGGCACAGTCCCCGTATTGATTGTGATATTCAGCTGGAGACCATTCCCTTGAAACTCTCTCAGCTGCAATACCGGCAAATCAT
GGAATTCCTCAAGGAGCTGGAACGAAAGGAGAGGCAGGTGAAGTTCCGAAGGTGGAAACCCAAGGTGGCGATATCTAAGAACTGCCGAGA
ATGGTGGTATTTTGCTTTGAATGCTAACTTGTATGAGATCAGAGAGCAGAGGAAACGTTGCACCTGGGACTTTATGTTGCACCGCGCTCG
TGATGCTGTATCTTACACTGACAAATATTTCAACAAGTTAAAAGGAGGCCTGCTGTCCACAGATGACAAGGAGGAAATGTGTCGGATTGA
AGAGGAACAGAGCTTTGAGGAATTGAAGATTTTGCGTGAACTGGTTCATGATCGATTTCACAAACAGGAAGAACTAGCAGAGAGTCTGCG
GGAGCCTCAGTTTGATTCTCCAGGAGCCTGTCCGGGAGCCCCAGAACCCGGTGGAGGCAGTGGGATGCTGCAGTATCTCCAGTCCTGGTT
TCCTGGATGGGGTGGCTGGTACGGGCAGCAGACCCCAGAAGGGAATGTGGTTGAGGGACTGTCAGCAGAGCAACAGGAGCAGTGGATTCC
TGAAGAGATCCTGGGCACTGAGGAGTTTTTTGACCCCACTGCAGATGCCTCGTGTATGAACACGTATACAAAGCGAGATCATGTCTTTGC
CAAACTGAATTTGCAGTTGCAGCGAGGTACAGTGACTCTGTTACACAAGGAGCAAGGAACTCCTCAAATGAATGAAAGTGCTTTCATGCA
GCTCGAGTTTTCAGATGTAAAACTTCTAGCAGAGTCTCTTCCTCGAAGAAATTCCTCGTTGCTTTCAGTCCGGTTGGGTGGACTGTTTCT
TCGAGACCTGGCTACAGAAGGAACTATGTTTCCTCTTCTAGTCTTCCCTAATCCACAAAAAGAAGTTGGCAGAGTCTCACAATCTTTTGG
TCTACAAACTACATCTGCAGACAGAAGTGATCATTACCCAGCTGCAGATCCAGATGGCCCCGTTTTTGAGATGCTGTATGAGAGAAATCC
GGCGCACAGCCACTTTGAGAGGCGGCTCAATGTCAGCACAAGGCCCTTGAACATCATATACAATCCGCAGGCCATTAAAAAAGTAGCAGA
CTTTTTCTACAAGGGAAAGGTTCATACCTCAGGTTTTGGTTATCAGTCTGAACTTGAGCTGAGAGTGGCTGAAGCTGCCCGAAGACAATA
TAACAAGCTGAAGATGCAGACCAAGGCAGAAATCCGGCAAACTCTTGATCGTTTGCTAGTGGGTGATTTCATTGAGGAGAGTAAACGATG
GACCGTGCGGCTGGATATTTCTGCCCCTCAGGTGATATTTCCTGATGATTTCAAATTCAAGAATCCTGTGTTAGTTGTCGTGGATCTAGG
AAGAATGCTTTTGACGAACACCCAAGATAACTCCAGGAGGAAAAGTAGGGATGGGTCAGCATCTGAAGAGACCCAGTTTAGTGATGATGA
ATATAAGACCCCCCTGGCCACACCTCCTAACACCCCACCTCCCGAGTCAAGCAGCAGCAACGGAGAGAAAACACCTCCCTTTTCTGGAGT
TGAGTTCAGTGAAGAACAGCTTCAAGCACATTTAATGAGCACAAAGATGTATGAGAGGTACTCGCTGTCATTTATGGACCTCCAGATCAT
GGTTGGACGAGTGAAAGACAATTGGAAGCATGTCCAGGATATTGACGTGGGACCAACACATGTGGTAGAGAAGTTCAACGTTCACCTACA
GTTAGAGCGTCGATTGATTTATACTTCAGATCCCAAATATCCAGGAGCCGTGCTCTCAGGCAACTTACCAGACTTAAAAATCCACATTAA
TGAAGATAAAATATCTGCACTAAAGAATTGCTTTGCTCTCCTCACCACCCCAGAAATGAAAACTTCTGACACTCAGATTAAAGAAAAGAT
TTTTCCCCAGGAGGAGCAGCGGGGAAGTTTGCAAGACTCCGTAATGAATTTAACCCAGAGCATTGTGTTGTTGGAGCAGCATACCCGCGA
GGTTCTGGTGGAGTCGCAGCTCCTCCTGGCGGAATTTAAAGTGAACTGTATGCAGCTTGGTGTTGAGAGCAATGGCCGGTACATTTCTGT
GCTCAAGGTGTTTGGTACCAATGCTCACTTTGTGAAGAGGCCTTATGATGCTGAAGTCTCCCTAACTGTTCATGGTTTGCTCCTGGTGGA
TACCATGCAGACATATGGTGCTGATTTTGACCTTTTGATGGCTTCACATAAGAACTTGAGCTTTGATATTCCAACGGGAAGCCTTCGGGA
TAGCAGGGCCCAGTCTCCTGTCTCTGGACCGAATGTGGCCCACTTAACTGATGGAGCTACACTGAACGACCGATCAGCTACTAGTGTTTC
ACTTGACAAAATTCTTACCAAAGAGCAAGAGTCCCTTATTAAGTTGGAATATCAGTTTGTGAGTTCAGAGTGCCCATCGATGAATTTAGA
CAGTACTCTTCAGGTGATTTCCCTACAGGTGAATAATTTAGATATTATCCTCAATCCAGAGACGATTGTGGAGCTAATTGGTTTTCTTCA
AAAATCCTTTCCCAAGGAAAAAGATGATTTAAGTCCTCAACCTTTAATGACTGATTTTGAAAGAAGCTTCAGAGAACAAGGAACTTACCA
GTCTACATATGAACAAAACACTGAGGTTGCAGTGGAAATCCATAGGCTGAACTTACTGCTTCTTCGGACAGTGGGCATGGCAAATAGAGA
GAAATATGGCAGAAAAATTGCAACTGCAAGTATAGGTGGCACCAAAGTTAATGTCTCAATGGGTAGCACGTTTGACATGAATGGTTCTCT
TGGCTGTTTACAGCTTATGGATTTGACACAAGATAACGTTAAAAACCAGTATGTTGTCAGCATTGGGAATTCTGTAGGCTATGAAAATAT
CATCAGTGATATTGGCTACTTTGAATCTGTGTTTGTCAGAATGGAAGATGCAGCCCTCACTGAAGCTTTGAGTTTCACGTTTGTTGAGAG
ATCTAAACAGGAGTGTTTTCTCAACCTGAAGATGGCTTCTTTACATTATAACCACTCTGCTAAGTTTTTGAAGGAGTTGACGTTATCCAT
GGATGAACTGGAAGAAAATTTTCGAGGTATGCTGAAAAGCGCAGCCACCAAAGTCACCACAGTACTAGCTACCAAGACTGCCGAGTATAG
CGAGATGGTATCGCTCTTTGAAACTCCAAGGAAGACTCGGGAACCCTTTATCTTAGAGGAAAATGAAATATATGGGTTTGACCTAGCTTC
GTCTCATTTGGACACTGTAAAGCTAATCTTGAACATAAACATTGAATCACCAGTTGTTTCTATCCCTCGGAAGCCGGGGAGTCCTGAGTT
GTTGGTGGGACACTTGGGACAGATATTCATCCAGAATTTTGTGGCGGGAGATGATGAATCCAGAAGTGACCGTCTGCAGGTGGAAATCAA
GGACATTAAACTGTATTCTTTGAATTGCACCCAGTTGGCAGGTAGAGAAGCTGTTGGGTCTGAAGGAAGCCGGATGTTTTGCCCACCTTC
CGGGTCTGGCAGTGCCAACAGTCAGGAGGAAGCTCATTTCACACGACATGATTTCTTTGAATCTTTGCATAGAGGTCAAGCTTTTCACAT
CCTGAACAACACCACCATTCAGTTTAAACTGGAGAAGATCCCTATAGAGAGAGAATCTGAATTGACTTTTTCTCTTAGCCCAGATGACCT
GGGAACTTCTAGCATCATGAAGATTGAAGGAAAATTTGTCAATCCAGTTCAGGTGGTGTTAGCAAAGCATGTATATGAGCAGGTTTTACA
AACCCTGGACAATCTCGTGTACAGTGAAGATCTGAATAAGTATCCAGCCAGTGCTACCTCCTCCCCTTGCCCTGATTCTCCTCTGCCTCC
CCTCAGTACCTGTGGAGAATCTTCTGTTGAAAGGAAGGAGAATGGATTGTTCAGCCACTCCAGCCTTTCTAACACCTCTCAGAAGTCATT
GTCAGTGAAGGAAGTCAAATCCTTTACTCAGATTCAAGCCACCTTTTGTATATCAGAGCTTCAGGTTCAGCTAAGTGGAGATCTGACTTT
GGGGGCCCAAGGTCTTGTGAGCTTAAAGTTTCAGGACTTTGAGGTGGAATTCAGTAAAGACCATCCCCAGACTTTATCTATTCAGATTGC
CCTGCATTCTCTGCTGATGGAGGACTTATTGGAGAAGAATCCAGATTCTAAATATAAGAACCTGATGGTGTCTCGAGGAGCCCCTAAGCC
ATCTAGTTTAGCACAAAAAGAATACCTTTCTCAGTCTTGCCCCTCAGTGTCCAATGTGGAATATCCTGATATGCCTCGGTCTCTCCCTTC
CCACATGGAAGAAGCTCCTAATGTCTTCCAGTTGTATCAAAGGCCCACCTCTGCGTCCCGGAAAAAGCAAAAGGAAGTCCAAGACAAGGA
CTATCCCTTGACCCCACCTCCTTCTCCAACAGTGGATGAGCCCAAGATACTTGTTGGAAAGAGTAAATTTGATGATTCCTTAGTCCACAT
CAACATATTCTTGGTAGATAAGAAACATCCAGAATTCTCTTCCAGTTACAATCGAGTTAACCGGAGCATTGATGTTGATTTTAATTGCTT
GGATGTGCTGATCACACTGCAAACCTGGGTTGTGATATTAGACTTTTTTGGAATCGGCTCCACTGCAGACAACCACGCAATGAGGCTGCC
TCCTGAGGGCATTCTGCACAACGTGAAGTTGGAGCCACATGCCTCCATGGAGTCTGGACTTCAGGATCCAGTGAACACCAAACTGGATCT
CAAGGTTCATTCACTTTCTCTAGTGCTGAATAAGACCACCAGTGAGCTTGCCAAAGCAAATGTGTCCAAATTAGTAGCACACCTGGAAAT
GATTGAGGGAGACCTGGCCTTACAGGGCAGCATTGGGAGTCTGTCTCTAAGTGACCTCACATGCCATGGAGAGTTCTACAGAGAACGGTT
CACTACCAGTGGTGAAGAAGCACTCATCTTCCAGACTTTTAAATACGGACGGCCTGACCCTCTGCTCCGGAGAGAACACGACATTCGCGT
GAGCCTCCGGATGGCCTCTGTGCAGTATGTGCATACTCAGCGTTTCCAGGCAGAGGTGGTGGCCTTCATTCAGCATTTCACTCAGCTGCA
GGATGTCTTAGGGCGCCAGCGAGCTGCTATTGAGGGGCAGACGGTGAGAGATCAAGCCCAGCGCTGTTCACGGGTTCTCCTGGATATTGA
GGCTGGTGCTCCCGTTCTCTTGATCCCAGAAAGTTCCAGATCAAATAATCTGATTGTAGCAAATTTGGGGAAGTTGAAAGTCAAAAATAA
GTTTCTGTTTGCTGGTTTTCCTGGCACCTTTTCCCTACAAGATAAGGAATCTGTGCCTTCAGCTTCCCCAACGGGTATTCCCAAACACAG
TCTGAGGAAAACGACAAGCACGGAGGAGCCCAGGGGAACCCATTCCCAGGGGCAGTTCACGATGCCTCTTGCTGGAATGAGCCTAGGAAG
CCTGAAGAGTGAGTTTGTGCCCAGTACCTCCACCAAGCAGCAAGGGCCGCAACCCACACTGTCTGTTGGCCAAGAGTCCAGTAGTCCAGA
AGACCATGTCTGCCTGCTGGATTGCGTTGTCGTGGATCTCCAGGACATGGACATCTTTGCTGCAGAGAGACATCCGAGAGAATACTCGAA
GGCACCAGAGGATAGTAGTGGAGATCTGATCTTCCCTTCCTATTTTGTGCGACAGACAGGAGGAAGCCTCTTAACCGAGCCTTGTAGGCT
GAAATTGCAGGTGGAAAGGAATTTGGACAAAGAAATAAGTCATACTGTGCCAGACATATCTATCCATGGCAATCTCTCCTCAGTCCACTG
CTCTCTGGATCTGTATAAATACAAGCTGATCCGCGGCTTATTAGAGAACAACCTGGGAGAACCCATAGAGGAATTTATGCGGCCTTATGA
TTTACAAGATCCAAGAATTCATACTGTCCTGAGTGGAGAAGTGTACACCTGTATGTGCTTCCTCATTGATATGGTGAATGTAAGTCTGGA
GCTTAAAGATCCAAAAAGAAAAGAAGGTGCTGGGTCCCTAGCCAGATTTGACTTCAAGAAATGCAAACTGCTCTATGAAAGTTTTTCCAA
CCAAACCAAGTCCATTAACTTGGTTTCCCATTCCATGATGGCTTTTGACACCCGTTATGCTGGGCAGAAGACCAGCCCTGGCATGACGAA
TGTGTTCAGCTGTATCTTTCAGCCCGCTAAGAACAGCAGCACCACCCAAGGGTCCATTCAGATTGAACTACATTTCAGATCTACCAAGGA
TTCCTCCTGCTTTACAGTAGTTCTCAACAATCTCCGTGTGTTTCTCATATTTGACTGGCTACTGTTAGTCCATGATTTTCTCCACACTCC
CAGTGATATTAAGAAACAAAATCATGTTACTCCTTCTCGCCACCGTAACTCTAGCAGCGAATCTGCTATAGTTCCCAAAACTGTGAAGAG
TGGAGTAGTTACCAAGCGGTCTTCCCTTCCTGTGTCCAATGAAAGGCACCTGGAGGTCAAGGTCAATGTAACAGGTACGGAGTTTGTGGT
CATTGAAGATGTGTCCTGCTTCGACACCAATGCCATTATTCTGAAAGGCACCACAGTGCTCACCTATAAGCCCCGGTTTGTTGATCGCCC
CTTTTCAGGAAGTTTGTTTGGCATTGAGGTGTTTTCATGCCGACTAGGGAATGAGCATGATACAGCTCTTTCAATTGTGGATCCCGTACA
AATTCAAATGGAGTTGGTGGGGAATTCTTCTTATCAAAATAGTTCAGGATTGATGGATGCATTCAATAGTGAAGATTTCCCACCTGTCCT
GGAGATTCAGTTACAAGCCCTGGATATCAGACTCTCCTATAATGATGTTCAGCTGTTTCTTGCCATTGCAAAATCCATCCCAGAGCAAGC
TAATGCTGCAGTGCCAGACTCAGTGGCCCTGGAGTCAGACTCCGTTGGCACTTACCTTCCAGGTGCATCTCGCGTTGGAGAGGAAATCAG
AGAAGGGACAAGACACACCTTAGATCCTGTCTTGGAGTTACAGCTGGCTAGGCTGCAGGAGCTGGGATTCAGCATGGATGATTGTCGCAA
AGCTCTTTTGGCGTGTCAAGGCCAATTGAAAAAGGCAGCAAGTTGGTTGTTTAAGAATGCGGAACCTCTGAAGTCTCTTTCCTTGGCCTC
CACCAGCCGAGATAGCCCAGGGGCTGTGGCAGCGCCATTGATCTCTGGCGTGGAGATCAAAGCTGAGAGTGTGTGCATCTGTTTCATCGA
TGACTGCATGGATTGTGATGTTCCTCTCGCTGAACTCACCTTTTCCCGTCTGAATTTTCTTCAGCGTGTAAGAACTAGCCCTGAAGGCTA
TGCCCACTTCACCCTTTCTGGAGATTATTATAACCGTGCTCTTTCAGGCTGGGAGCCATTTATTGAGCCTTGGCCATGCTCTGTATCCTG
GCAACAGCAGGCAGCTAGTCGTCTCCATCCTCCTCGACTGAAGCTAGAAGCCAAGGCCAAACCTCGTTTGGATATCAATATCACTTCTGT
GCTAATTGACCAGTATGTAAGTACCAAGGAATCGTGGATGGCAGATTACTGTAAAGATGACAAGGACATAGAGTCAGCTAAATCAGAAGA
CTGGATGGGCTCTTCGGTGGATCCTCCATGTTTTGGACAAAGCCTCCCCCTTGTCTACCTTAGAACTAGGAGTACAGCCAGTCTGACTAA
CCTAGAGCACCAGATCTATGCTAGAGCAGAGGTGAAAACCCCCAAGCGCCGGCAGCCATTTGTCCCCTTTGCTCTGAGGAACCACACGGG
GTGCACTTTGTGGTTTGCCACCCTGACCACCACACCCACCAGAGCTGCACTCTCTCACAGTGGGAGTCCAGGGGTAGTTCCAGAAGGGAA
CGGAACATTTCTCGATGATACTCACAATGTTAGTGAATGGCGAGAAGTCCTTACAGGTGAAGAGATTCCCTTTGAATTTGAAGCAAGAGG
AAAGTTAAGACACAGACACACCCATGACCTCCGGATTCATCAACTGCAAGTGAGAGTAAATGGCTGGGAGCAAGTGAGCCCAGTGTCTGT
GGACAAAGTCGGGACCTTTTTTCGATATGCAGCACCAGATAAAAATTCATCTTCCTCTACGATTGGCAGCCCAAGCAGCAGAACAAATAT
TATACATCCCCAGGTTTATTTCTCTTCACTCCCACCAGTGCGGGTGGTCTTTGCAGTGACTATGGAAGGCAGTGCACGGAAAGTCATCAC
TGTCCGGTCAGCCCTCATTGTGAGGAACAGACTTGAGACACCAATGGAACTAAGACTGGATAGCCCATCAGCTCCAGACAAGCCAGTGGT
GCTTCCTGCTATCATGCCAGGGGATTCGTTTGCTGTGCCTTTACACCTCACTTCTTGGCGGCTACAGGCCCGGCCCAAAGGATTGGGTGT
ATTTTTCTGTAAGGCTCCCATTCATTGGACCAATGTAGTGAAGACTGCAGAAATTAGTAGCAGTAAACGAGAGTGCCACTCTATGGACAC
AGAAAAAAGCCGATTTTTCAGGTTTTGTGTGGCTATAAAGAAAGAGAATTATCCAGATTATATGCCCTCAAACATATTTTCTGACAGTGC
AAAACAGATTTTCAGACAGCCTGGGCATACCATATATCTCCTGCCAACTGTGGTAATCTGCAACTTGCTACCCTGTGAACTTGATTTTTA
TGTTAAAGGAATGCCAATTAATGGGACGCTGAAACCTGGCAAGGAGGCAGCTCTCCATACAGCTGATACATCCCAGAACATTGAGCTGGG
GGTATCACTGGAGAATTTCCCCCTCTGTAAAGAATTGCTCATTCCACCTGGAACCCAAAACTATATGGTGAGAATGCGACTCTATGACGT
CAACCGTCGGCAGCTGAACCTCACCATCCGGATTGTGTGTCGAGCAGAAGGATCCTTAAAGATCTTCATTTCTGCTCCATATTGGCTGAT
TAACAAAACAGGGTTGCCACTGATCTTCAGACAGGACAATGCCAAGACAGATGCTGCAGGCCAGTTTGAGGAGCATGAGCTGGCCCGTAG
CCTGAGTCCTCTCTTATTCTGCTATGCTGACAAAGAGCAGCCAAACCTCTGCACGATGAGAATCGGAAGGGGGATTCATCCAGAAGGCAT
GCCGGGCTGGTGTCAGGGCTTCTCCCTGGATGGTGGTAGTGGTGTCCGAGCTTTGAAAGTCATCCAGCAAGGAAACCGCCCAGGGCTGAT
CTATAACATTGGTATTGATGTCAAGAAAGGCCGAGGTCGATACATTGATACCTGCATGGTCATCTTTGCCCCCCGTTACCTGTTAGATAA
TAAATCATCTCACAAGCTTGCATTTGCACAGAGGGAATTTGCCAGGGGACAGGGAACAGCCAATCCCGAAGGTTACATTTCCACCCTTCC
TGGTTCCAGTGTGGTGTTCCACTGGCCTCGGAATGACTATGATCAGCTATTGTGTGTCAGACTGATGGACGTTCCCAATTGTATTTGGTC
TGGAGGCTTTGAAGTCAACAAGAATAATTCCTTCCATATCAACATGAGGGATACCTTGGGAAAATGCTTCTTCCTACGAGTGGAAATTAC
TCTCCGAGGAGCTACGTATAGGATCTCATTTAGTGACACAGATCAGTTACCTCCTCCTTTCCGAATTGACAACTTTTCTAAGGTCCCGGT
TGTCTTTACTCAGCATGGCGTAGCTGAACCCAGGCTCCGGACTGAAGTGAAGCCCATGACTTCATTGGATTATGCCTGGGACGAACCCAC
CTTGCCACCTTTTATCACTCTGACTGTTAAAGGGGCAGGGTCCTCTGAGATCAACTGCAACATGAATGATTTCCAGGATAATCGGCAGCT
TTATTATGAAAATTTCATTTACATTGCTGCTACATATACATTCTCTGGCTTGCAGGAGGGAACAGGCAGGCCTGTGGCTTCCAACAAGGC
CATTACCTGTGCGGAGCTCGTTTTGGATGTCTCACCCAAGACACAAAGAGTCATTTTAAAAAAGAAGGAACCAGGAAAGCGTTCTCAGCT
GTGGAGGATGACAGGAACAGGAATGCTGGCCCATGAGGGCTCCTCAGTTCCTCACAATCCCAATAAGCCCTCAGCCGCCCGCTCCACCGA
GGGGTCTGCCATCTTAGATATTGCTGGTCTCGCTGCAGTGACTGACAACAGATACGAGCCACTGATGCTGAGAAAGCCTGACCGCAGGCG
AAGCACAACTCAGACGTGGAGTTTCCGAGAAGGAAAACTGACCTGTGGGTTACATGGGTTGGTCGTCCAGGCCAAAGGAGGACTTTCTGG
TTTGTTTGATGGAGCTGAAGTTGTTCTTGGTCCTGACACTTCCATGGAGCTTTTGGGGCCAGTTCCACCTGAACAACAATTTATTAATCA
AAAAATGAGACCTGGTTCTGGAATGTTATCCATCAGAGTCATCCCAGATGGACCAACTAGAGCACTCCAGATAACAGATTTCTGCCACCG
GAAAAGCAGCCGTTCATATGAAGTGGATGAACTTCCTGTCACCGAACAAGAGCTGCAGAAATTAAAGAATCCAGATACAGAGCAGGAATT
GGAAGTGCTTGTGAGGTTAGAAGGTGGAATTGGGTTGTCCTTAATTAATAAAGTCCCAGAAGAACTGGTCTTTGCAAGTCTTACAGGAAT
CAATGTGCACTATACACAGCTGGCAACCAGTCACATGCTTGAACTCAGCATACAGGATGTACAGGTGGACAATCAGCTCATTGGTACCAC
GCAGCCCTTCATGCTCTATGTGACTCCCCTGAGCAATGAGAATGAGGTCATCGAGACCGGCCCAGCTGTGCAAGTCAACGCAGTGAAGTT
CCCCAGTAAGAGTGCACTGACCAACATCTACAAGCATCTGATGATCACAGCTCAGAGATTCACAGTGCAAATTGAGGAGAAACTGCTCCT
CAAGCTGCTAAGTTTCTTTGGCTACGATCAAGCAGAATCAGAGGTGGAAAAATATGATGAAAACCTCCATGAAAAGACAGCTGAGCAAGG
TGGAACACCAATTCGATACTACTTTGAAAATCTCAAAATCAGCATTCCTCAGATCAAGCTAAGTGTGTTCACCTCCAACAAGCTCCCATT
GGATCTTAAGGCCCTAAAAAGCACCTTGGGGTTTCCTTTGATACGGTTTGAAGACGCTGTGATTAATCTAGATCCATTCACTCGGGTACA
TCCCTATGAGACCAAGGAGTTCATCATCAATGATATCCTCAAACATTTCCAGGAGTTTCTTGGCAATCCTATGGGGCTTTTGAATGATGT
TTCTGAAGGGGTTACTGGACTGATAAAATATGGAAATGTCGGGGGCCTCATCAGAAATGTTACACACGGAGTATCAAACTCTGCTGCCAA
GCAAGAAAAACGGATATTTACAAACTTCCATCGCCAGCTTTTTTGTTGGATTGACAAGTGGATCGATCTCACGATGGAAGACATTAGGAG
AATGGAAGACGAGACTCAGAAAGAACTAGAAACAATGCGTAAGAGGGGTTCCGTTCGAGGCACGTCGGCTGCTGATGTCTAGATGAGTCC
CCTGTAGGGTCAGAGACAATGTCAAACTGTTTACGTAATCAAGGTCAAGTGAGGGGAACAAGCGCAGCCAGTGATGAGTGAAGAAGAATC
TGACCAGTATCTTGCAGTGTTGACGTTTCCCAGATGTGTGCTTGTGATGATACACACACATGCACAGGTTCTCAACCACGTGTGTATATA
TGTATGTGTGCATATGTCTGTAGCTGTATATAAAGCGCATGTAGAGCTACAGATCCAGATACACACACTTGTGTATATATGTACATACAG
ACATACTGAAGGGATTAGTACAATTTCTCCAAAGTACTGTACCTATCTTCAGCAAGAATGCAAAAGAAAATATTTTCAATATATATACCT
GGAACAGATTTTAATAATTATCAGAGTAATACCATTAATGGACAAATTGACTGCAATGTAATACTAGCTGGTATGTTTCATAAATGTCAA
GCTGTGGACCAACATATATAGCCTTTTATTATTTTTCTCTTCTTTTAAGTCAGTCTGTTATAAATTTTTTTTTAGTCCCATAAGCAGTAG
ACTCCCACAGAAAATTTCTTCAAAATTTTTTGGTGTTCCAATGAATCTGGGATGTAAACTCTGAATGTATTTATAACTATTTATTTCTGG
ATGGTCATTATCTTGTAGCCAAATTTGACAATATAAAGTAAGGAGCAAAGTTACAGGCCAGTTTTTACTTGTTTGCCCTGAGGGAAAAAT
CCTTTTAAAAAAAATTTCTGGTTTTTATTGGATTTTTGTATTTTAAATTTCAAATATTTTTCTACATCAAACCTAGCAAAAATGGAGATG
ACGGTTTCTGATTTATAATAAATACTAGACAGTTTTCAGGCTCCTGTTAGACAAACACATTGATGAAGAAATTAGTCTTAATAGGATTGT
AGGCTGTGTAGAAAAGTTGGAAATATAGCACTTCATGGAGTCTTGTTTTGAAGATGACAGTTTTCTGTAACTACAGCTTGGAAACTATGC
AAATGGTCTAGATTCCTCAGAGCTCACATGATAGGATATAGTTAGTGATGACATTTTGCTCTTCTTGTGGGAACACACACTTCAAGGAGG
AGATAGTGACTTTGAGATAGGAACAGTTTAAGATGCAGTGTGAGTCTGGCCTGCGTGCGGTGAGGAGGCCCCGCCAAGAGACTGGTGGAC
ATCTGACTGTGGGATGTGCTCTCAAGTAGGACGTCATCAGGACAGATTCTGAATAGGCATCATGAGAGTGCTGGTCAGAAACGGCTGCCA
CTTTTTTTAATTTAATTTTATTTTTTATTTAAAGGAAGGAACAATAGCTAGGTAAGATTTTTATCAGCTTTCTCTGTCTGAATCCAGTTT
TTCCTCTGTCAGTCCTGGAAGCTTGAATAGAATTATATTGTTGAAGCCTTCAGGTCACAAACTGTCTTTTGTAACCTCCTGTCCCTCCTA
AAACACGCCAACCCCTGCAGTCAAATCACATTAGTAATCTGATTTGCTGACAGTCCTGCCCTGCCTGCTCCTCGTTTTCCCACATGTCCT
GCATCCCTCCCCCACTGGAGTGATTTCAGTGAATCAGACAAGGAAGGATGTGTAGGATCACTACTGCATTGCAATACCCTGTTATCCTCA
GCAACAAAACCCACATTTCATACATCCTTTGTGTACTCAGGATAAAGACTGATGTTTACTCTCTGGGCACTGTTGTAAGATAGGTTTTGT
CAGAGCATAATCATTGTCTGCAAAGTGTTTGGTGCGAGGAAGATTATTGCTAATTTTGTGAAATAAAGAGTCTAGCCCTCTCCTTTTAAT
GAACTTAACTCTCGCTGGCATCTGTAGTATCATTGGGAGCTTAGGCGCACATGGAAATGAGAGCCCGGCGCATGGATTTTAATGTTTTTC
TAACAACTGTGGAGATTTGAGGGAATGTGTGGTGAATGTAAAATACCTAGTTTACTTGCCAGTCTCTTGTGTAAATTACAGTAAAACAAA

>98331_98331_5_VPS13D-PITPNB_VPS13D_chr1_12476754_ENST00000358136_PITPNB_chr22_28254502_ENST00000335272_length(amino acids)=4153AA_BP=4096
MLEGLVAWVLNTYLGKYVNNLNTDQLSVALLKGAVELENLPLKKDALKELELPFEVKAGFIGKVTLQIPFYRPHVDPWVISISSLHLIGA
PEKIQDFNDEKEKLLERERKKALLQALEEKWKNDRQQKGESYWYSVTASVVTRIVENIELKIQDVHLRFEDGVTNPSHPFAFGICIKNVS
MQNAVNEPVQKLMRKKQLDVAEFSIYWDVDCTLLGDLPQMELQEAMARSMESRSHHYVLEPVFASALLKRNCSKKPLRSRHSPRIDCDIQ
LETIPLKLSQLQYRQIMEFLKELERKERQVKFRRWKPKVAISKNCREWWYFALNANLYEIREQRKRCTWDFMLHRARDAVSYTDKYFNKL
KGGLLSTDDKEEMCRIEEEQSFEELKILRELVHDRFHKQEELAESLREPQFDSPGACPGAPEPGGGSGMLQYLQSWFPGWGGWYGQQTPE
GNVVEGLSAEQQEQWIPEEILGTEEFFDPTADASCMNTYTKRDHVFAKLNLQLQRGTVTLLHKEQGTPQMNESAFMQLEFSDVKLLAESL
PRRNSSLLSVRLGGLFLRDLATEGTMFPLLVFPNPQKEVGRVSQSFGLQTTSADRSDHYPAADPDGPVFEMLYERNPAHSHFERRLNVST
RPLNIIYNPQAIKKVADFFYKGKVHTSGFGYQSELELRVAEAARRQYNKLKMQTKAEIRQTLDRLLVGDFIEESKRWTVRLDISAPQVIF
PDDFKFKNPVLVVVDLGRMLLTNTQDNSRRKSRDGSASEETQFSDDEYKTPLATPPNTPPPESSSSNGEKTPPFSGVEFSEEQLQAHLMS
TKMYERYSLSFMDLQIMVGRVKDNWKHVQDIDVGPTHVVEKFNVHLQLERRLIYTSDPKYPGAVLSGNLPDLKIHINEDKISALKNCFAL
LTTPEMKTSDTQIKEKIFPQEEQRGSLQDSVMNLTQSIVLLEQHTREVLVESQLLLAEFKVNCMQLGVESNGRYISVLKVFGTNAHFVKR
PYDAEVSLTVHGLLLVDTMQTYGADFDLLMASHKNLSFDIPTGSLRDSRAQSPVSGPNVAHLTDGATLNDRSATSVSLDKILTKEQESLI
KLEYQFVSSECPSMNLDSTLQVISLQVNNLDIILNPETIVELIGFLQKSFPKEKDDLSPQPLMTDFERSFREQGTYQSTYEQNTEVAVEI
HRLNLLLLRTVGMANREKYGRKIATASIGGTKVNVSMGSTFDMNGSLGCLQLMDLTQDNVKNQYVVSIGNSVGYENIISDIGYFESVFVR
MEDAALTEALSFTFVERSKQECFLNLKMASLHYNHSAKFLKELTLSMDELEENFRGMLKSAATKVTTVLATKTAEYSEMVSLFETPRKTR
EPFILEENEIYGFDLASSHLDTVKLILNINIESPVVSIPRKPGSPELLVGHLGQIFIQNFVAGDDESRSDRLQVEIKDIKLYSLNCTQLA
GREAVGSEGSRMFCPPSGSGSANSQEEAHFTRHDFFESLHRGQAFHILNNTTIQFKLEKIPIERESELTFSLSPDDLGTSSIMKIEGKFV
NPVQVVLAKHVYEQVLQTLDNLVYSEDLNKYPASATSSPCPDSPLPPLSTCGESSVERKENGLFSHSSLSNTSQKSLSVKEVKSFTQIQA
TFCISELQVQLSGDLTLGAQGLVSLKFQDFEVEFSKDHPQTLSIQIALHSLLMEDLLEKNPDSKYKNLMVSRGAPKPSSLAQKEYLSQSC
PSVSNVEYPDMPRSLPSHMEEAPNVFQLYQRPTSASRKKQKEVQDKDYPLTPPPSPTVDEPKILVGKSKFDDSLVHINIFLVDKKHPEFS
SSYNRVNRSIDVDFNCLDVLITLQTWVVILDFFGIGSTADNHAMRLPPEGILHNVKLEPHASMESGLQDPVNTKLDLKVHSLSLVLNKTT
SELAKANVSKLVAHLEMIEGDLALQGSIGSLSLSDLTCHGEFYRERFTTSGEEALIFQTFKYGRPDPLLRREHDIRVSLRMASVQYVHTQ
RFQAEVVAFIQHFTQLQDVLGRQRAAIEGQTVRDQAQRCSRVLLDIEAGAPVLLIPESSRSNNLIVANLGKLKVKNKFLFAGFPGTFSLQ
DKESVPSASPTGIPKHSLRKTTSTEEPRGTHSQGQFTMPLAGMSLGSLKSEFVPSTSTKQQGPQPTLSVGQESSSPEDHVCLLDCVVVDL
QDMDIFAAERHPREYSKAPEDSSGDLIFPSYFVRQTGGSLLTEPCRLKLQVERNLDKEISHTVPDISIHGNLSSVHCSLDLYKYKLIRGL
LENNLGEPIEEFMRPYDLQDPRIHTVLSGEVYTCMCFLIDMVNVSLELKDPKRKEGAGSLARFDFKKCKLLYESFSNQTKSINLVSHSMM
AFDTRYAGQKTSPGMTNVFSCIFQPAKNSSTTQGSIQIELHFRSTKDSSCFTVVLNNLRVFLIFDWLLLVHDFLHTPSDIKKQNHVTPSR
HRNSSSESAIVPKTVKSGVVTKRSSLPVSNERHLEVKVNVTGTEFVVIEDVSCFDTNAIILKGTTVLTYKPRFVDRPFSGSLFGIEVFSC
RLGNEHDTALSIVDPVQIQMELVGNSSYQNSSGLMDAFNSEDFPPVLEIQLQALDIRLSYNDVQLFLAIAKSIPEQANAAVPDSVALESD
SVGTYLPGASRVGEEIREGTRHTLDPVLELQLARLQELGFSMDDCRKALLACQGQLKKAASWLFKNAEPLKSLSLASTSRDSPGAVAAPL
ISGVEIKAESVCICFIDDCMDCDVPLAELTFSRLNFLQRVRTSPEGYAHFTLSGDYYNRALSGWEPFIEPWPCSVSWQQQAASRLHPPRL
KLEAKAKPRLDINITSVLIDQYVSTKESWMADYCKDDKDIESAKSEDWMGSSVDPPCFGQSLPLVYLRTRSTASLTNLEHQIYARAEVKT
PKRRQPFVPFALRNHTGCTLWFATLTTTPTRAALSHSGSPGVVPEGNGTFLDDTHNVSEWREVLTGEEIPFEFEARGKLRHRHTHDLRIH
QLQVRVNGWEQVSPVSVDKVGTFFRYAAPDKNSSSSTIGSPSSRTNIIHPQVYFSSLPPVRVVFAVTMEGSARKVITVRSALIVRNRLET
PMELRLDSPSAPDKPVVLPAIMPGDSFAVPLHLTSWRLQARPKGLGVFFCKAPIHWTNVVKTAEISSSKRECHSMDTEKSRFFRFCVAIK
KENYPDYMPSNIFSDSAKQIFRQPGHTIYLLPTVVICNLLPCELDFYVKGMPINGTLKPGKEAALHTADTSQNIELGVSLENFPLCKELL
IPPGTQNYMVRMRLYDVNRRQLNLTIRIVCRAEGSLKIFISAPYWLINKTGLPLIFRQDNAKTDAAGQFEEHELARSLSPLLFCYADKEQ
PNLCTMRIGRGIHPEGMPGWCQGFSLDGGSGVRALKVIQQGNRPGLIYNIGIDVKKGRGRYIDTCMVIFAPRYLLDNKSSHKLAFAQREF
ARGQGTANPEGYISTLPGSSVVFHWPRNDYDQLLCVRLMDVPNCIWSGGFEVNKNNSFHINMRDTLGKCFFLRVEITLRGATYRISFSDT
DQLPPPFRIDNFSKVPVVFTQHGVAEPRLRTEVKPMTSLDYAWDEPTLPPFITLTVKGAGSSEINCNMNDFQDNRQLYYENFIYIAATYT
FSGLQEGTGRPVASNKAITCAELVLDVSPKTQRVILKKKEPGKRSQLWRMTGTGMLAHEGSSVPHNPNKPSAARSTEGSAILDIAGLAAV
TDNRYEPLMLRKPDRRRSTTQTWSFREGKLTCGLHGLVVQAKGGLSGLFDGAEVVLGPDTSMELLGPVPPEQQFINQKMRPGSGMLSIRV
IPDGPTRALQITDFCHRKSSRSYEVDELPVTEQELQKLKNPDTEQELEVLVRLEGGIGLSLINKVPEELVFASLTGINVHYTQLATSHML
ELSIQDVQVDNQLIGTTQPFMLYVTPLSNENEVIETGPAVQVNAVKFPSKSALTNIYKHLMITAQRFTVQIEEKLLLKLLSFFGYDQAES
EVEKYDENLHEKTAEQGGTPIRYYFENLKISIPQIKLSVFTSNKLPLDLKALKSTLGFPLIRFEDAVINLDPFTRVHPYETKEFIINDIL
KHFQEFLGNPMGLLNDVSEGVTGLIKYGNVGGLIRNVTHGVSNSAAKQEKRIFTNFHRQLFCWIDKWIDLTMEDIRRMEDETQKELETMR

--------------------------------------------------------------
>98331_98331_6_VPS13D-PITPNB_VPS13D_chr1_12476754_ENST00000358136_PITPNB_chr22_28254502_ENST00000455418_length(transcript)=14622nt_BP=12421nt
GGAGGAAACGCCGCGCAGCGCCGGGCTGGGGCGGGCGGCCCGGGACACCGACAGATTTTTCTGTGACCATGAAAGAGAGAAATAAAGAAT
GATCCATGATTTCTAAACACCTTTTCCTGAGGATATAGTCATGTTGGAAGGCCTTGTAGCCTGGGTTCTCAATACCTATTTGGGAAAATA
TGTCAATAACCTGAACACTGACCAGCTCTCAGTTGCACTTCTCAAAGGTGCTGTTGAATTAGAAAACTTGCCATTAAAGAAAGATGCCTT
GAAAGAATTGGAATTACCATTTGAAGTCAAAGCTGGCTTCATTGGGAAAGTAACCCTTCAGATTCCCTTTTATCGCCCCCATGTGGACCC
TTGGGTGATCTCCATCTCCAGCCTTCACTTAATTGGAGCCCCAGAGAAAATACAGGATTTCAATGATGAAAAGGAGAAGCTGTTGGAAAG
GGAACGTAAGAAAGCACTACTTCAAGCCCTGGAGGAGAAATGGAAGAATGACCGCCAGCAGAAAGGGGAGTCCTATTGGTATTCAGTTAC
CGCCTCCGTAGTTACAAGGATTGTGGAGAATATTGAATTAAAAATTCAAGATGTCCATTTACGCTTTGAAGATGGTGTCACCAATCCCTC
CCATCCTTTTGCTTTTGGCATCTGCATTAAGAATGTGTCCATGCAAAATGCTGTGAATGAGCCTGTACAGAAACTAATGCGGAAAAAGCA
ATTAGACGTAGCAGAATTTAGCATCTATTGGGATGTCGATTGCACTTTACTGGGGGATTTGCCTCAGATGGAGTTACAGGAGGCCATGGC
CAGGAGCATGGAGAGTCGCAGCCATCACTACGTCCTGGAGCCTGTGTTTGCATCTGCTCTTTTGAAGAGAAACTGCTCCAAGAAGCCCCT
GCGGTCTCGGCACAGTCCCCGTATTGATTGTGATATTCAGCTGGAGACCATTCCCTTGAAACTCTCTCAGCTGCAATACCGGCAAATCAT
GGAATTCCTCAAGGAGCTGGAACGAAAGGAGAGGCAGGTGAAGTTCCGAAGGTGGAAACCCAAGGTGGCGATATCTAAGAACTGCCGAGA
ATGGTGGTATTTTGCTTTGAATGCTAACTTGTATGAGATCAGAGAGCAGAGGAAACGTTGCACCTGGGACTTTATGTTGCACCGCGCTCG
TGATGCTGTATCTTACACTGACAAATATTTCAACAAGTTAAAAGGAGGCCTGCTGTCCACAGATGACAAGGAGGAAATGTGTCGGATTGA
AGAGGAACAGAGCTTTGAGGAATTGAAGATTTTGCGTGAACTGGTTCATGATCGATTTCACAAACAGGAAGAACTAGCAGAGAGTCTGCG
GGAGCCTCAGTTTGATTCTCCAGGAGCCTGTCCGGGAGCCCCAGAACCCGGTGGAGGCAGTGGGATGCTGCAGTATCTCCAGTCCTGGTT
TCCTGGATGGGGTGGCTGGTACGGGCAGCAGACCCCAGAAGGGAATGTGGTTGAGGGACTGTCAGCAGAGCAACAGGAGCAGTGGATTCC
TGAAGAGATCCTGGGCACTGAGGAGTTTTTTGACCCCACTGCAGATGCCTCGTGTATGAACACGTATACAAAGCGAGATCATGTCTTTGC
CAAACTGAATTTGCAGTTGCAGCGAGGTACAGTGACTCTGTTACACAAGGAGCAAGGAACTCCTCAAATGAATGAAAGTGCTTTCATGCA
GCTCGAGTTTTCAGATGTAAAACTTCTAGCAGAGTCTCTTCCTCGAAGAAATTCCTCGTTGCTTTCAGTCCGGTTGGGTGGACTGTTTCT
TCGAGACCTGGCTACAGAAGGAACTATGTTTCCTCTTCTAGTCTTCCCTAATCCACAAAAAGAAGTTGGCAGAGTCTCACAATCTTTTGG
TCTACAAACTACATCTGCAGACAGAAGTGATCATTACCCAGCTGCAGATCCAGATGGCCCCGTTTTTGAGATGCTGTATGAGAGAAATCC
GGCGCACAGCCACTTTGAGAGGCGGCTCAATGTCAGCACAAGGCCCTTGAACATCATATACAATCCGCAGGCCATTAAAAAAGTAGCAGA
CTTTTTCTACAAGGGAAAGGTTCATACCTCAGGTTTTGGTTATCAGTCTGAACTTGAGCTGAGAGTGGCTGAAGCTGCCCGAAGACAATA
TAACAAGCTGAAGATGCAGACCAAGGCAGAAATCCGGCAAACTCTTGATCGTTTGCTAGTGGGTGATTTCATTGAGGAGAGTAAACGATG
GACCGTGCGGCTGGATATTTCTGCCCCTCAGGTGATATTTCCTGATGATTTCAAATTCAAGAATCCTGTGTTAGTTGTCGTGGATCTAGG
AAGAATGCTTTTGACGAACACCCAAGATAACTCCAGGAGGAAAAGTAGGGATGGGTCAGCATCTGAAGAGACCCAGTTTAGTGATGATGA
ATATAAGACCCCCCTGGCCACACCTCCTAACACCCCACCTCCCGAGTCAAGCAGCAGCAACGGAGAGAAAACACCTCCCTTTTCTGGAGT
TGAGTTCAGTGAAGAACAGCTTCAAGCACATTTAATGAGCACAAAGATGTATGAGAGGTACTCGCTGTCATTTATGGACCTCCAGATCAT
GGTTGGACGAGTGAAAGACAATTGGAAGCATGTCCAGGATATTGACGTGGGACCAACACATGTGGTAGAGAAGTTCAACGTTCACCTACA
GTTAGAGCGTCGATTGATTTATACTTCAGATCCCAAATATCCAGGAGCCGTGCTCTCAGGCAACTTACCAGACTTAAAAATCCACATTAA
TGAAGATAAAATATCTGCACTAAAGAATTGCTTTGCTCTCCTCACCACCCCAGAAATGAAAACTTCTGACACTCAGATTAAAGAAAAGAT
TTTTCCCCAGGAGGAGCAGCGGGGAAGTTTGCAAGACTCCGTAATGAATTTAACCCAGAGCATTGTGTTGTTGGAGCAGCATACCCGCGA
GGTTCTGGTGGAGTCGCAGCTCCTCCTGGCGGAATTTAAAGTGAACTGTATGCAGCTTGGTGTTGAGAGCAATGGCCGGTACATTTCTGT
GCTCAAGGTGTTTGGTACCAATGCTCACTTTGTGAAGAGGCCTTATGATGCTGAAGTCTCCCTAACTGTTCATGGTTTGCTCCTGGTGGA
TACCATGCAGACATATGGTGCTGATTTTGACCTTTTGATGGCTTCACATAAGAACTTGAGCTTTGATATTCCAACGGGAAGCCTTCGGGA
TAGCAGGGCCCAGTCTCCTGTCTCTGGACCGAATGTGGCCCACTTAACTGATGGAGCTACACTGAACGACCGATCAGCTACTAGTGTTTC
ACTTGACAAAATTCTTACCAAAGAGCAAGAGTCCCTTATTAAGTTGGAATATCAGTTTGTGAGTTCAGAGTGCCCATCGATGAATTTAGA
CAGTACTCTTCAGGTGATTTCCCTACAGGTGAATAATTTAGATATTATCCTCAATCCAGAGACGATTGTGGAGCTAATTGGTTTTCTTCA
AAAATCCTTTCCCAAGGAAAAAGATGATTTAAGTCCTCAACCTTTAATGACTGATTTTGAAAGAAGCTTCAGAGAACAAGGAACTTACCA
GTCTACATATGAACAAAACACTGAGGTTGCAGTGGAAATCCATAGGCTGAACTTACTGCTTCTTCGGACAGTGGGCATGGCAAATAGAGA
GAAATATGGCAGAAAAATTGCAACTGCAAGTATAGGTGGCACCAAAGTTAATGTCTCAATGGGTAGCACGTTTGACATGAATGGTTCTCT
TGGCTGTTTACAGCTTATGGATTTGACACAAGATAACGTTAAAAACCAGTATGTTGTCAGCATTGGGAATTCTGTAGGCTATGAAAATAT
CATCAGTGATATTGGCTACTTTGAATCTGTGTTTGTCAGAATGGAAGATGCAGCCCTCACTGAAGCTTTGAGTTTCACGTTTGTTGAGAG
ATCTAAACAGGAGTGTTTTCTCAACCTGAAGATGGCTTCTTTACATTATAACCACTCTGCTAAGTTTTTGAAGGAGTTGACGTTATCCAT
GGATGAACTGGAAGAAAATTTTCGAGGTATGCTGAAAAGCGCAGCCACCAAAGTCACCACAGTACTAGCTACCAAGACTGCCGAGTATAG
CGAGATGGTATCGCTCTTTGAAACTCCAAGGAAGACTCGGGAACCCTTTATCTTAGAGGAAAATGAAATATATGGGTTTGACCTAGCTTC
GTCTCATTTGGACACTGTAAAGCTAATCTTGAACATAAACATTGAATCACCAGTTGTTTCTATCCCTCGGAAGCCGGGGAGTCCTGAGTT
GTTGGTGGGACACTTGGGACAGATATTCATCCAGAATTTTGTGGCGGGAGATGATGAATCCAGAAGTGACCGTCTGCAGGTGGAAATCAA
GGACATTAAACTGTATTCTTTGAATTGCACCCAGTTGGCAGGTAGAGAAGCTGTTGGGTCTGAAGGAAGCCGGATGTTTTGCCCACCTTC
CGGGTCTGGCAGTGCCAACAGTCAGGAGGAAGCTCATTTCACACGACATGATTTCTTTGAATCTTTGCATAGAGGTCAAGCTTTTCACAT
CCTGAACAACACCACCATTCAGTTTAAACTGGAGAAGATCCCTATAGAGAGAGAATCTGAATTGACTTTTTCTCTTAGCCCAGATGACCT
GGGAACTTCTAGCATCATGAAGATTGAAGGAAAATTTGTCAATCCAGTTCAGGTGGTGTTAGCAAAGCATGTATATGAGCAGGTTTTACA
AACCCTGGACAATCTCGTGTACAGTGAAGATCTGAATAAGTATCCAGCCAGTGCTACCTCCTCCCCTTGCCCTGATTCTCCTCTGCCTCC
CCTCAGTACCTGTGGAGAATCTTCTGTTGAAAGGAAGGAGAATGGATTGTTCAGCCACTCCAGCCTTTCTAACACCTCTCAGAAGTCATT
GTCAGTGAAGGAAGTCAAATCCTTTACTCAGATTCAAGCCACCTTTTGTATATCAGAGCTTCAGGTTCAGCTAAGTGGAGATCTGACTTT
GGGGGCCCAAGGTCTTGTGAGCTTAAAGTTTCAGGACTTTGAGGTGGAATTCAGTAAAGACCATCCCCAGACTTTATCTATTCAGATTGC
CCTGCATTCTCTGCTGATGGAGGACTTATTGGAGAAGAATCCAGATTCTAAATATAAGAACCTGATGGTGTCTCGAGGAGCCCCTAAGCC
ATCTAGTTTAGCACAAAAAGAATACCTTTCTCAGTCTTGCCCCTCAGTGTCCAATGTGGAATATCCTGATATGCCTCGGTCTCTCCCTTC
CCACATGGAAGAAGCTCCTAATGTCTTCCAGTTGTATCAAAGGCCCACCTCTGCGTCCCGGAAAAAGCAAAAGGAAGTCCAAGACAAGGA
CTATCCCTTGACCCCACCTCCTTCTCCAACAGTGGATGAGCCCAAGATACTTGTTGGAAAGAGTAAATTTGATGATTCCTTAGTCCACAT
CAACATATTCTTGGTAGATAAGAAACATCCAGAATTCTCTTCCAGTTACAATCGAGTTAACCGGAGCATTGATGTTGATTTTAATTGCTT
GGATGTGCTGATCACACTGCAAACCTGGGTTGTGATATTAGACTTTTTTGGAATCGGCTCCACTGCAGACAACCACGCAATGAGGCTGCC
TCCTGAGGGCATTCTGCACAACGTGAAGTTGGAGCCACATGCCTCCATGGAGTCTGGACTTCAGGATCCAGTGAACACCAAACTGGATCT
CAAGGTTCATTCACTTTCTCTAGTGCTGAATAAGACCACCAGTGAGCTTGCCAAAGCAAATGTGTCCAAATTAGTAGCACACCTGGAAAT
GATTGAGGGAGACCTGGCCTTACAGGGCAGCATTGGGAGTCTGTCTCTAAGTGACCTCACATGCCATGGAGAGTTCTACAGAGAACGGTT
CACTACCAGTGGTGAAGAAGCACTCATCTTCCAGACTTTTAAATACGGACGGCCTGACCCTCTGCTCCGGAGAGAACACGACATTCGCGT
GAGCCTCCGGATGGCCTCTGTGCAGTATGTGCATACTCAGCGTTTCCAGGCAGAGGTGGTGGCCTTCATTCAGCATTTCACTCAGCTGCA
GGATGTCTTAGGGCGCCAGCGAGCTGCTATTGAGGGGCAGACGGTGAGAGATCAAGCCCAGCGCTGTTCACGGGTTCTCCTGGATATTGA
GGCTGGTGCTCCCGTTCTCTTGATCCCAGAAAGTTCCAGATCAAATAATCTGATTGTAGCAAATTTGGGGAAGTTGAAAGTCAAAAATAA
GTTTCTGTTTGCTGGTTTTCCTGGCACCTTTTCCCTACAAGATAAGGAATCTGTGCCTTCAGCTTCCCCAACGGGTATTCCCAAACACAG
TCTGAGGAAAACGACAAGCACGGAGGAGCCCAGGGGAACCCATTCCCAGGGGCAGTTCACGATGCCTCTTGCTGGAATGAGCCTAGGAAG
CCTGAAGAGTGAGTTTGTGCCCAGTACCTCCACCAAGCAGCAAGGGCCGCAACCCACACTGTCTGTTGGCCAAGAGTCCAGTAGTCCAGA
AGACCATGTCTGCCTGCTGGATTGCGTTGTCGTGGATCTCCAGGACATGGACATCTTTGCTGCAGAGAGACATCCGAGAGAATACTCGAA
GGCACCAGAGGATAGTAGTGGAGATCTGATCTTCCCTTCCTATTTTGTGCGACAGACAGGAGGAAGCCTCTTAACCGAGCCTTGTAGGCT
GAAATTGCAGGTGGAAAGGAATTTGGACAAAGAAATAAGTCATACTGTGCCAGACATATCTATCCATGGCAATCTCTCCTCAGTCCACTG
CTCTCTGGATCTGTATAAATACAAGCTGATCCGCGGCTTATTAGAGAACAACCTGGGAGAACCCATAGAGGAATTTATGCGGCCTTATGA
TTTACAAGATCCAAGAATTCATACTGTCCTGAGTGGAGAAGTGTACACCTGTATGTGCTTCCTCATTGATATGGTGAATGTAAGTCTGGA
GCTTAAAGATCCAAAAAGAAAAGAAGGTGCTGGGTCCCTAGCCAGATTTGACTTCAAGAAATGCAAACTGCTCTATGAAAGTTTTTCCAA
CCAAACCAAGTCCATTAACTTGGTTTCCCATTCCATGATGGCTTTTGACACCCGTTATGCTGGGCAGAAGACCAGCCCTGGCATGACGAA
TGTGTTCAGCTGTATCTTTCAGCCCGCTAAGAACAGCAGCACCACCCAAGGGTCCATTCAGATTGAACTACATTTCAGATCTACCAAGGA
TTCCTCCTGCTTTACAGTAGTTCTCAACAATCTCCGTGTGTTTCTCATATTTGACTGGCTACTGTTAGTCCATGATTTTCTCCACACTCC
CAGTGATATTAAGAAACAAAATCATGTTACTCCTTCTCGCCACCGTAACTCTAGCAGCGAATCTGCTATAGTTCCCAAAACTGTGAAGAG
TGGAGTAGTTACCAAGCGGTCTTCCCTTCCTGTGTCCAATGAAAGGCACCTGGAGGTCAAGGTCAATGTAACAGGTACGGAGTTTGTGGT
CATTGAAGATGTGTCCTGCTTCGACACCAATGCCATTATTCTGAAAGGCACCACAGTGCTCACCTATAAGCCCCGGTTTGTTGATCGCCC
CTTTTCAGGAAGTTTGTTTGGCATTGAGGTGTTTTCATGCCGACTAGGGAATGAGCATGATACAGCTCTTTCAATTGTGGATCCCGTACA
AATTCAAATGGAGTTGGTGGGGAATTCTTCTTATCAAAATAGTTCAGGATTGATGGATGCATTCAATAGTGAAGATTTCCCACCTGTCCT
GGAGATTCAGTTACAAGCCCTGGATATCAGACTCTCCTATAATGATGTTCAGCTGTTTCTTGCCATTGCAAAATCCATCCCAGAGCAAGC
TAATGCTGCAGTGCCAGACTCAGTGGCCCTGGAGTCAGACTCCGTTGGCACTTACCTTCCAGGTGCATCTCGCGTTGGAGAGGAAATCAG
AGAAGGGACAAGACACACCTTAGATCCTGTCTTGGAGTTACAGCTGGCTAGGCTGCAGGAGCTGGGATTCAGCATGGATGATTGTCGCAA
AGCTCTTTTGGCGTGTCAAGGCCAATTGAAAAAGGCAGCAAGTTGGTTGTTTAAGAATGCGGAACCTCTGAAGTCTCTTTCCTTGGCCTC
CACCAGCCGAGATAGCCCAGGGGCTGTGGCAGCGCCATTGATCTCTGGCGTGGAGATCAAAGCTGAGAGTGTGTGCATCTGTTTCATCGA
TGACTGCATGGATTGTGATGTTCCTCTCGCTGAACTCACCTTTTCCCGTCTGAATTTTCTTCAGCGTGTAAGAACTAGCCCTGAAGGCTA
TGCCCACTTCACCCTTTCTGGAGATTATTATAACCGTGCTCTTTCAGGCTGGGAGCCATTTATTGAGCCTTGGCCATGCTCTGTATCCTG
GCAACAGCAGGCAGCTAGTCGTCTCCATCCTCCTCGACTGAAGCTAGAAGCCAAGGCCAAACCTCGTTTGGATATCAATATCACTTCTGT
GCTAATTGACCAGTATGTAAGTACCAAGGAATCGTGGATGGCAGATTACTGTAAAGATGACAAGGACATAGAGTCAGCTAAATCAGAAGA
CTGGATGGGCTCTTCGGTGGATCCTCCATGTTTTGGACAAAGCCTCCCCCTTGTCTACCTTAGAACTAGGAGTACAGCCAGTCTGACTAA
CCTAGAGCACCAGATCTATGCTAGAGCAGAGGTGAAAACCCCCAAGCGCCGGCAGCCATTTGTCCCCTTTGCTCTGAGGAACCACACGGG
GTGCACTTTGTGGTTTGCCACCCTGACCACCACACCCACCAGAGCTGCACTCTCTCACAGTGGGAGTCCAGGGGTAGTTCCAGAAGGGAA
CGGAACATTTCTCGATGATACTCACAATGTTAGTGAATGGCGAGAAGTCCTTACAGGTGAAGAGATTCCCTTTGAATTTGAAGCAAGAGG
AAAGTTAAGACACAGACACACCCATGACCTCCGGATTCATCAACTGCAAGTGAGAGTAAATGGCTGGGAGCAAGTGAGCCCAGTGTCTGT
GGACAAAGTCGGGACCTTTTTTCGATATGCAGCACCAGATAAAAATTCATCTTCCTCTACGATTGGCAGCCCAAGCAGCAGAACAAATAT
TATACATCCCCAGGTTTATTTCTCTTCACTCCCACCAGTGCGGGTGGTCTTTGCAGTGACTATGGAAGGCAGTGCACGGAAAGTCATCAC
TGTCCGGTCAGCCCTCATTGTGAGGAACAGACTTGAGACACCAATGGAACTAAGACTGGATAGCCCATCAGCTCCAGACAAGCCAGTGGT
GCTTCCTGCTATCATGCCAGGGGATTCGTTTGCTGTGCCTTTACACCTCACTTCTTGGCGGCTACAGGCCCGGCCCAAAGGATTGGGTGT
ATTTTTCTGTAAGGCTCCCATTCATTGGACCAATGTAGTGAAGACTGCAGAAATTAGTAGCAGTAAACGAGAGTGCCACTCTATGGACAC
AGAAAAAAGCCGATTTTTCAGGTTTTGTGTGGCTATAAAGAAAGAGAATTATCCAGATTATATGCCCTCAAACATATTTTCTGACAGTGC
AAAACAGATTTTCAGACAGCCTGGGCATACCATATATCTCCTGCCAACTGTGGTAATCTGCAACTTGCTACCCTGTGAACTTGATTTTTA
TGTTAAAGGAATGCCAATTAATGGGACGCTGAAACCTGGCAAGGAGGCAGCTCTCCATACAGCTGATACATCCCAGAACATTGAGCTGGG
GGTATCACTGGAGAATTTCCCCCTCTGTAAAGAATTGCTCATTCCACCTGGAACCCAAAACTATATGGTGAGAATGCGACTCTATGACGT
CAACCGTCGGCAGCTGAACCTCACCATCCGGATTGTGTGTCGAGCAGAAGGATCCTTAAAGATCTTCATTTCTGCTCCATATTGGCTGAT
TAACAAAACAGGGTTGCCACTGATCTTCAGACAGGACAATGCCAAGACAGATGCTGCAGGCCAGTTTGAGGAGCATGAGCTGGCCCGTAG
CCTGAGTCCTCTCTTATTCTGCTATGCTGACAAAGAGCAGCCAAACCTCTGCACGATGAGAATCGGAAGGGGGATTCATCCAGAAGGCAT
GCCGGGCTGGTGTCAGGGCTTCTCCCTGGATGGTGGTAGTGGTGTCCGAGCTTTGAAAGTCATCCAGCAAGGAAACCGCCCAGGGCTGAT
CTATAACATTGGTATTGATGTCAAGAAAGGCCGAGGTCGATACATTGATACCTGCATGGTCATCTTTGCCCCCCGTTACCTGTTAGATAA
TAAATCATCTCACAAGCTTGCATTTGCACAGAGGGAATTTGCCAGGGGACAGGGAACAGCCAATCCCGAAGGTTACATTTCCACCCTTCC
TGGTTCCAGTGTGGTGTTCCACTGGCCTCGGAATGACTATGATCAGCTATTGTGTGTCAGACTGATGGACGTTCCCAATTGTATTTGGTC
TGGAGGCTTTGAAGTCAACAAGAATAATTCCTTCCATATCAACATGAGGGATACCTTGGGAAAATGCTTCTTCCTACGAGTGGAAATTAC
TCTCCGAGGAGCTACGTATAGGATCTCATTTAGTGACACAGATCAGTTACCTCCTCCTTTCCGAATTGACAACTTTTCTAAGGTCCCGGT
TGTCTTTACTCAGCATGGCGTAGCTGAACCCAGGCTCCGGACTGAAGTGAAGCCCATGACTTCATTGGATTATGCCTGGGACGAACCCAC
CTTGCCACCTTTTATCACTCTGACTGTTAAAGGGGCAGGGTCCTCTGAGATCAACTGCAACATGAATGATTTCCAGGATAATCGGCAGCT
TTATTATGAAAATTTCATTTACATTGCTGCTACATATACATTCTCTGGCTTGCAGGAGGGAACAGGCAGGCCTGTGGCTTCCAACAAGGC
CATTACCTGTGCGGAGCTCGTTTTGGATGTCTCACCCAAGACACAAAGAGTCATTTTAAAAAAGAAGGAACCAGGAAAGCGTTCTCAGCT
GTGGAGGATGACAGGAACAGGAATGCTGGCCCATGAGGGCTCCTCAGTTCCTCACAATCCCAATAAGCCCTCAGCCGCCCGCTCCACCGA
GGGGTCTGCCATCTTAGATATTGCTGGTCTCGCTGCAGTGACTGACAACAGATACGAGCCACTGATGCTGAGAAAGCCTGACCGCAGGCG
AAGCACAACTCAGACGTGGAGTTTCCGAGAAGGAAAACTGACCTGTGGGTTACATGGGTTGGTCGTCCAGGCCAAAGGAGGACTTTCTGG
TTTGTTTGATGGAGCTGAAGTTGTTCTTGGTCCTGACACTTCCATGGAGCTTTTGGGGCCAGTTCCACCTGAACAACAATTTATTAATCA
AAAAATGAGACCTGGTTCTGGAATGTTATCCATCAGAGTCATCCCAGATGGACCAACTAGAGCACTCCAGATAACAGATTTCTGCCACCG
GAAAAGCAGCCGTTCATATGAAGTGGATGAACTTCCTGTCACCGAACAAGAGCTGCAGAAATTAAAGAATCCAGATACAGAGCAGGAATT
GGAAGTGCTTGTGAGGTTAGAAGGTGGAATTGGGTTGTCCTTAATTAATAAAGTCCCAGAAGAACTGGTCTTTGCAAGTCTTACAGGAAT
CAATGTGCACTATACACAGCTGGCAACCAGTCACATGCTTGAACTCAGCATACAGGATGTACAGGTGGACAATCAGCTCATTGGTACCAC
GCAGCCCTTCATGCTCTATGTGACTCCCCTGAGCAATGAGAATGAGGTCATCGAGACCGGCCCAGCTGTGCAAGTCAACGCAGTGAAGTT
CCCCAGTAAGAGTGCACTGACCAACATCTACAAGCATCTGATGATCACAGCTCAGAGATTCACAGTGCAAATTGAGGAGAAACTGCTCCT
CAAGCTGCTAAGTTTCTTTGGCTACGATCAAGCAGAATCAGAGGTGGAAAAATATGATGAAAACCTCCATGAAAAGACAGCTGAGCAAGG
TGGAACACCAATTCGATACTACTTTGAAAATCTCAAAATCAGCATTCCTCAGATCAAGCTAAGTGTGTTCACCTCCAACAAGCTCCCATT
GGATCTTAAGGCCCTAAAAAGCACCTTGGGGTTTCCTTTGATACGGTTTGAAGACGCTGTGATTAATCTAGATCCATTCACTCGGGTACA
TCCCTATGAGACCAAGGAGTTCATCATCAATGATATCCTCAAACATTTCCAGGAGTTTCTTGGCAATCCTATGGGGCTTTTGAATGATGT
TTCTGAAGGGGTTACTGGACTGATAAAATATGGAAATGTCGGGGGCCTCATCAGAAATGTTACACACGGAGTATCAAACTCTGCTGCCAA
GCAAGAAAAACGGATATTTACAAACTTCCATCGCCAGCTTTTTTGTTGGATTGACAAGTGGATCGATCTCACGATGGAAGACATTAGGAG
AATGGAAGACGAGACTCAGAAAGAACTAGAAACAATGCGTAAGAGGGGTTCCGTTCGAGGCACGTCGGCTGCTGATGTCTAGATGAGTCC
CCTGTAGGGTCAGAGACAATGTCAAACTGTTTACGTAATCAAGGTCAAGTGAGGGGAACAAGCGCAGCCAGTGATGAGTGAAGAAGAATC
TGACCAGTATCTTGCAGTGTTGACGTTTCCCAGATGTGTGCTTGTGATGATACACACACATGCACAGGTTCTCAACCACGTGTGTATATA
TGTATGTGTGCATATGTCTGTAGCTGTATATAAAGCGCATGTAGAGCTACAGATCCAGATACACACACTTGTGTATATATGTACATACAG
ACATACTGAAGGGATTAGTACAATTTCTCCAAAGTACTGTACCTATCTTCAGCAAGAATGCAAAAGAAAATATTTTCAATATATATACCT
GGAACAGATTTTAATAATTATCAGAGTAATACCATTAATGGACAAATTGACTGCAATGTAATACTAGCTGGTATGTTTCATAAATGTCAA
GCTGTGGACCAACATATATAGCCTTTTATTATTTTTCTCTTCTTTTAAGTCAGTCTGTTATAAATTTTTTTTTAGTCCCATAAGCAGTAG
ACTCCCACAGAAAATTTCTTCAAAATTTTTTGGTGTTCCAATGAATCTGGGATGTAAACTCTGAATGTATTTATAACTATTTATTTCTGG
ATGGTCATTATCTTGTAGCCAAATTTGACAATATAAAGTAAGGAGCAAAGTTACAGGCCAGTTTTTACTTGTTTGCCCTGAGGGAAAAAT
CCTTTTAAAAAAAATTTCTGGTTTTTATTGGATTTTTGTATTTTAAATTTCAAATATTTTTCTACATCAAACCTAGCAAAAATGGAGATG
ACGGTTTCTGATTTATAATAAATACTAGACAGTTTTCAGGCTCCTGTTAGACAAACACATTGATGAAGAAATTAGTCTTAATAGGATTGT
AGGCTGTGTAGAAAAGTTGGAAATATAGCACTTCATGGAGTCTTGTTTTGAAGATGACAGTTTTCTGTAACTACAGCTTGGAAACTATGC
AAATGGTCTAGATTCCTCAGAGCTCACATGATAGGATATAGTTAGTGATGACATTTTGCTCTTCTTGTGGGAACACACACTTCAAGGAGG
AGATAGTGACTTTGAGATAGGAACAGTTTAAGATGCAGTGTGAGTCTGGCCTGCGTGCGGTGAGGAGGCCCCGCCAAGAGACTGGTGGAC
ATCTGACTGTGGGATGTGCTCTCAAGTAGGACGTCATCAGGACAGATTCTGAATAGGCATCATGAGAGTGCTGGTCAGAAACGGCTGCCA
CTTTTTTTAATTTAATTTTATTTTTTATTTAAAGGAAGGAACAATAGCTAGGTAAGATTTTTATCAGCTTTCTCTGTCTGAATCCAGTTT
TTCCTCTGTCAGTCCTGGAAGCTTGAATAGAATTATATTGTTGAAGCCTTCAGGTCACAAACTGTCTTTTGTAACCTCCTGTCCCTCCTA
AAACACGCCAACCCCTGCAGTCAAATCACATTAGTAATCTGATTTGCTGACAGTCCTGCCCTGCCTGCTCCTCGTTTTCCCACATGTCCT
GCATCCCTCCCCCACTGGAGTGATTTCAGTGAATCAGACAAGGAAGGATGTGTAGGATCACTACTGCATTGCAATACCCTGTTATCCTCA
GCAACAAAACCCACATTTCATACATCCTTTGTGTACTCAGGATAAAGACTGATGTTTACTCTCTGGGCACTGTTGTAAGATAGGTTTTGT
CAGAGCATAATCATTGTCTGCAAAGTGTTTGGTGCGAGGAAGATTATTGCTAATTTTGTGAAATAAAGAGTCTAGCCCTCTCCTTTTAAT
GAACTTAACTCTCGCTGGCATCTGTAGTATCATTGGGAGCTTAGGCGCACATGGAAATGAGAGCCCGGCGCATGGATTTTAATGTTTTTC
TAACAACTGTGGAGATTTGAGGGAATGTGTGGTGAATGTAAAATACCTAGTTTACTTGCCAGTCTCTTGTGTAAATTACAGTAAAACAAA

>98331_98331_6_VPS13D-PITPNB_VPS13D_chr1_12476754_ENST00000358136_PITPNB_chr22_28254502_ENST00000455418_length(amino acids)=4153AA_BP=4096
MLEGLVAWVLNTYLGKYVNNLNTDQLSVALLKGAVELENLPLKKDALKELELPFEVKAGFIGKVTLQIPFYRPHVDPWVISISSLHLIGA
PEKIQDFNDEKEKLLERERKKALLQALEEKWKNDRQQKGESYWYSVTASVVTRIVENIELKIQDVHLRFEDGVTNPSHPFAFGICIKNVS
MQNAVNEPVQKLMRKKQLDVAEFSIYWDVDCTLLGDLPQMELQEAMARSMESRSHHYVLEPVFASALLKRNCSKKPLRSRHSPRIDCDIQ
LETIPLKLSQLQYRQIMEFLKELERKERQVKFRRWKPKVAISKNCREWWYFALNANLYEIREQRKRCTWDFMLHRARDAVSYTDKYFNKL
KGGLLSTDDKEEMCRIEEEQSFEELKILRELVHDRFHKQEELAESLREPQFDSPGACPGAPEPGGGSGMLQYLQSWFPGWGGWYGQQTPE
GNVVEGLSAEQQEQWIPEEILGTEEFFDPTADASCMNTYTKRDHVFAKLNLQLQRGTVTLLHKEQGTPQMNESAFMQLEFSDVKLLAESL
PRRNSSLLSVRLGGLFLRDLATEGTMFPLLVFPNPQKEVGRVSQSFGLQTTSADRSDHYPAADPDGPVFEMLYERNPAHSHFERRLNVST
RPLNIIYNPQAIKKVADFFYKGKVHTSGFGYQSELELRVAEAARRQYNKLKMQTKAEIRQTLDRLLVGDFIEESKRWTVRLDISAPQVIF
PDDFKFKNPVLVVVDLGRMLLTNTQDNSRRKSRDGSASEETQFSDDEYKTPLATPPNTPPPESSSSNGEKTPPFSGVEFSEEQLQAHLMS
TKMYERYSLSFMDLQIMVGRVKDNWKHVQDIDVGPTHVVEKFNVHLQLERRLIYTSDPKYPGAVLSGNLPDLKIHINEDKISALKNCFAL
LTTPEMKTSDTQIKEKIFPQEEQRGSLQDSVMNLTQSIVLLEQHTREVLVESQLLLAEFKVNCMQLGVESNGRYISVLKVFGTNAHFVKR
PYDAEVSLTVHGLLLVDTMQTYGADFDLLMASHKNLSFDIPTGSLRDSRAQSPVSGPNVAHLTDGATLNDRSATSVSLDKILTKEQESLI
KLEYQFVSSECPSMNLDSTLQVISLQVNNLDIILNPETIVELIGFLQKSFPKEKDDLSPQPLMTDFERSFREQGTYQSTYEQNTEVAVEI
HRLNLLLLRTVGMANREKYGRKIATASIGGTKVNVSMGSTFDMNGSLGCLQLMDLTQDNVKNQYVVSIGNSVGYENIISDIGYFESVFVR
MEDAALTEALSFTFVERSKQECFLNLKMASLHYNHSAKFLKELTLSMDELEENFRGMLKSAATKVTTVLATKTAEYSEMVSLFETPRKTR
EPFILEENEIYGFDLASSHLDTVKLILNINIESPVVSIPRKPGSPELLVGHLGQIFIQNFVAGDDESRSDRLQVEIKDIKLYSLNCTQLA
GREAVGSEGSRMFCPPSGSGSANSQEEAHFTRHDFFESLHRGQAFHILNNTTIQFKLEKIPIERESELTFSLSPDDLGTSSIMKIEGKFV
NPVQVVLAKHVYEQVLQTLDNLVYSEDLNKYPASATSSPCPDSPLPPLSTCGESSVERKENGLFSHSSLSNTSQKSLSVKEVKSFTQIQA
TFCISELQVQLSGDLTLGAQGLVSLKFQDFEVEFSKDHPQTLSIQIALHSLLMEDLLEKNPDSKYKNLMVSRGAPKPSSLAQKEYLSQSC
PSVSNVEYPDMPRSLPSHMEEAPNVFQLYQRPTSASRKKQKEVQDKDYPLTPPPSPTVDEPKILVGKSKFDDSLVHINIFLVDKKHPEFS
SSYNRVNRSIDVDFNCLDVLITLQTWVVILDFFGIGSTADNHAMRLPPEGILHNVKLEPHASMESGLQDPVNTKLDLKVHSLSLVLNKTT
SELAKANVSKLVAHLEMIEGDLALQGSIGSLSLSDLTCHGEFYRERFTTSGEEALIFQTFKYGRPDPLLRREHDIRVSLRMASVQYVHTQ
RFQAEVVAFIQHFTQLQDVLGRQRAAIEGQTVRDQAQRCSRVLLDIEAGAPVLLIPESSRSNNLIVANLGKLKVKNKFLFAGFPGTFSLQ
DKESVPSASPTGIPKHSLRKTTSTEEPRGTHSQGQFTMPLAGMSLGSLKSEFVPSTSTKQQGPQPTLSVGQESSSPEDHVCLLDCVVVDL
QDMDIFAAERHPREYSKAPEDSSGDLIFPSYFVRQTGGSLLTEPCRLKLQVERNLDKEISHTVPDISIHGNLSSVHCSLDLYKYKLIRGL
LENNLGEPIEEFMRPYDLQDPRIHTVLSGEVYTCMCFLIDMVNVSLELKDPKRKEGAGSLARFDFKKCKLLYESFSNQTKSINLVSHSMM
AFDTRYAGQKTSPGMTNVFSCIFQPAKNSSTTQGSIQIELHFRSTKDSSCFTVVLNNLRVFLIFDWLLLVHDFLHTPSDIKKQNHVTPSR
HRNSSSESAIVPKTVKSGVVTKRSSLPVSNERHLEVKVNVTGTEFVVIEDVSCFDTNAIILKGTTVLTYKPRFVDRPFSGSLFGIEVFSC
RLGNEHDTALSIVDPVQIQMELVGNSSYQNSSGLMDAFNSEDFPPVLEIQLQALDIRLSYNDVQLFLAIAKSIPEQANAAVPDSVALESD
SVGTYLPGASRVGEEIREGTRHTLDPVLELQLARLQELGFSMDDCRKALLACQGQLKKAASWLFKNAEPLKSLSLASTSRDSPGAVAAPL
ISGVEIKAESVCICFIDDCMDCDVPLAELTFSRLNFLQRVRTSPEGYAHFTLSGDYYNRALSGWEPFIEPWPCSVSWQQQAASRLHPPRL
KLEAKAKPRLDINITSVLIDQYVSTKESWMADYCKDDKDIESAKSEDWMGSSVDPPCFGQSLPLVYLRTRSTASLTNLEHQIYARAEVKT
PKRRQPFVPFALRNHTGCTLWFATLTTTPTRAALSHSGSPGVVPEGNGTFLDDTHNVSEWREVLTGEEIPFEFEARGKLRHRHTHDLRIH
QLQVRVNGWEQVSPVSVDKVGTFFRYAAPDKNSSSSTIGSPSSRTNIIHPQVYFSSLPPVRVVFAVTMEGSARKVITVRSALIVRNRLET
PMELRLDSPSAPDKPVVLPAIMPGDSFAVPLHLTSWRLQARPKGLGVFFCKAPIHWTNVVKTAEISSSKRECHSMDTEKSRFFRFCVAIK
KENYPDYMPSNIFSDSAKQIFRQPGHTIYLLPTVVICNLLPCELDFYVKGMPINGTLKPGKEAALHTADTSQNIELGVSLENFPLCKELL
IPPGTQNYMVRMRLYDVNRRQLNLTIRIVCRAEGSLKIFISAPYWLINKTGLPLIFRQDNAKTDAAGQFEEHELARSLSPLLFCYADKEQ
PNLCTMRIGRGIHPEGMPGWCQGFSLDGGSGVRALKVIQQGNRPGLIYNIGIDVKKGRGRYIDTCMVIFAPRYLLDNKSSHKLAFAQREF
ARGQGTANPEGYISTLPGSSVVFHWPRNDYDQLLCVRLMDVPNCIWSGGFEVNKNNSFHINMRDTLGKCFFLRVEITLRGATYRISFSDT
DQLPPPFRIDNFSKVPVVFTQHGVAEPRLRTEVKPMTSLDYAWDEPTLPPFITLTVKGAGSSEINCNMNDFQDNRQLYYENFIYIAATYT
FSGLQEGTGRPVASNKAITCAELVLDVSPKTQRVILKKKEPGKRSQLWRMTGTGMLAHEGSSVPHNPNKPSAARSTEGSAILDIAGLAAV
TDNRYEPLMLRKPDRRRSTTQTWSFREGKLTCGLHGLVVQAKGGLSGLFDGAEVVLGPDTSMELLGPVPPEQQFINQKMRPGSGMLSIRV
IPDGPTRALQITDFCHRKSSRSYEVDELPVTEQELQKLKNPDTEQELEVLVRLEGGIGLSLINKVPEELVFASLTGINVHYTQLATSHML
ELSIQDVQVDNQLIGTTQPFMLYVTPLSNENEVIETGPAVQVNAVKFPSKSALTNIYKHLMITAQRFTVQIEEKLLLKLLSFFGYDQAES
EVEKYDENLHEKTAEQGGTPIRYYFENLKISIPQIKLSVFTSNKLPLDLKALKSTLGFPLIRFEDAVINLDPFTRVHPYETKEFIINDIL
KHFQEFLGNPMGLLNDVSEGVTGLIKYGNVGGLIRNVTHGVSNSAAKQEKRIFTNFHRQLFCWIDKWIDLTMEDIRRMEDETQKELETMR

--------------------------------------------------------------
>98331_98331_7_VPS13D-PITPNB_VPS13D_chr1_12476754_ENST00000543766_PITPNB_chr22_28254502_ENST00000320996_length(transcript)=2402nt_BP=285nt
ATGAGAGGAGAGAAACTCAGTAAGGCCCTAAAAAGCACCTTGGGGTTTCCTTTGATACGGTTTGAAGACGCTGTGATTAATCTAGATCCA
TTCACTCGGGTACATCCCTATGAGACCAAGGAGTTCATCATCAATGATATCCTCAAACATTTCCAGGAGTTTCTTGGCAATCCTATGGGG
CTTTTGAATGATGTTTCTGAAGGGGTTACTGGACTGATAAAATATGGAAATGTCGGGGGCCTCATCAGAAATGTTACACACGGAGTATCA
AACTCTGCTGCCAAGCAAGAAAAACGGATATTTACAAACTTCCATCGCCAGCTTTTTTGTTGGATTGACAAGTGGATCGATCTCACGATG
GAAGACATTAGGAGAATGGAAGACGAGACTCAGAAAGAACTAGAAACATTACGTAATCAAGGTCAAGTGAGGGGAACAAGCGCAGCCAGT
GATGAGTGAAGAAGAATCTGACCAGTATCTTGCAGTGTTGACGTTTCCCAGATGTGTGCTTGTGATGATACACACACATGCACAGGTTCT
CAACCACGTGTGTATATATGTATGTGTGCATATGTCTGTAGCTGTATATAAAGCGCATGTAGAGCTACAGATCCAGATACACACACTTGT
GTATATATGTACATACAGACATACTGAAGGGATTAGTACAATTTCTCCAAAGTACTGTACCTATCTTCAGCAAGAATGCAAAAGAAAATA
TTTTCAATATATATACCTGGAACAGATTTTAATAATTATCAGAGTAATACCATTAATGGACAAATTGACTGCAATGTAATACTAGCTGGT
ATGTTTCATAAATGTCAAGCTGTGGACCAACATATATAGCCTTTTATTATTTTTCTCTTCTTTTAAGTCAGTCTGTTATAAATTTTTTTT
TAGTCCCATAAGCAGTAGACTCCCACAGAAAATTTCTTCAAAATTTTTTGGTGTTCCAATGAATCTGGGATGTAAACTCTGAATGTATTT
ATAACTATTTATTTCTGGATGGTCATTATCTTGTAGCCAAATTTGACAATATAAAGTAAGGAGCAAAGTTACAGGCCAGTTTTTACTTGT
TTGCCCTGAGGGAAAAATCCTTTTAAAAAAAATTTCTGGTTTTTATTGGATTTTTGTATTTTAAATTTCAAATATTTTTCTACATCAAAC
CTAGCAAAAATGGAGATGACGGTTTCTGATTTATAATAAATACTAGACAGTTTTCAGGCTCCTGTTAGACAAACACATTGATGAAGAAAT
TAGTCTTAATAGGATTGTAGGCTGTGTAGAAAAGTTGGAAATATAGCACTTCATGGAGTCTTGTTTTGAAGATGACAGTTTTCTGTAACT
ACAGCTTGGAAACTATGCAAATGGTCTAGATTCCTCAGAGCTCACATGATAGGATATAGTTAGTGATGACATTTTGCTCTTCTTGTGGGA
ACACACACTTCAAGGAGGAGATAGTGACTTTGAGATAGGAACAGTTTAAGATGCAGTGTGAGTCTGGCCTGCGTGCGGTGAGGAGGCCCC
GCCAAGAGACTGGTGGACATCTGACTGTGGGATGTGCTCTCAAGTAGGACGTCATCAGGACAGATTCTGAATAGGCATCATGAGAGTGCT
GGTCAGAAACGGCTGCCACTTTTTTTAATTTAATTTTATTTTTTATTTAAAGGAAGGAACAATAGCTAGGTAAGATTTTTATCAGCTTTC
TCTGTCTGAATCCAGTTTTTCCTCTGTCAGTCCTGGAAGCTTGAATAGAATTATATTGTTGAAGCCTTCAGGTCACAAACTGTCTTTTGT
AACCTCCTGTCCCTCCTAAAACACGCCAACCCCTGCAGTCAAATCACATTAGTAATCTGATTTGCTGACAGTCCTGCCCTGCCTGCTCCT
CGTTTTCCCACATGTCCTGCATCCCTCCCCCACTGGAGTGATTTCAGTGAATCAGACAAGGAAGGATGTGTAGGATCACTACTGCATTGC
AATACCCTGTTATCCTCAGCAACAAAACCCACATTTCATACATCCTTTGTGTACTCAGGATAAAGACTGATGTTTACTCTCTGGGCACTG
TTGTAAGATAGGTTTTGTCAGAGCATAATCATTGTCTGCAAAGTGTTTGGTGCGAGGAAGATTATTGCTAATTTTGTGAAATAAAGAGTC
TAGCCCTCTCCTTTTAATGAACTTAACTCTCGCTGGCATCTGTAGTATCATTGGGAGCTTAGGCGCACATGGAAATGAGAGCCCGGCGCA
TGGATTTTAATGTTTTTCTAACAACTGTGGAGATTTGAGGGAATGTGTGGTGAATGTAAAATACCTAGTTTACTTGCCAGTCTCTTGTGT

>98331_98331_7_VPS13D-PITPNB_VPS13D_chr1_12476754_ENST00000543766_PITPNB_chr22_28254502_ENST00000320996_length(amino acids)=152AA_BP=94
MRGEKLSKALKSTLGFPLIRFEDAVINLDPFTRVHPYETKEFIINDILKHFQEFLGNPMGLLNDVSEGVTGLIKYGNVGGLIRNVTHGVS

--------------------------------------------------------------
>98331_98331_8_VPS13D-PITPNB_VPS13D_chr1_12476754_ENST00000543766_PITPNB_chr22_28254502_ENST00000335272_length(transcript)=2489nt_BP=285nt
ATGAGAGGAGAGAAACTCAGTAAGGCCCTAAAAAGCACCTTGGGGTTTCCTTTGATACGGTTTGAAGACGCTGTGATTAATCTAGATCCA
TTCACTCGGGTACATCCCTATGAGACCAAGGAGTTCATCATCAATGATATCCTCAAACATTTCCAGGAGTTTCTTGGCAATCCTATGGGG
CTTTTGAATGATGTTTCTGAAGGGGTTACTGGACTGATAAAATATGGAAATGTCGGGGGCCTCATCAGAAATGTTACACACGGAGTATCA
AACTCTGCTGCCAAGCAAGAAAAACGGATATTTACAAACTTCCATCGCCAGCTTTTTTGTTGGATTGACAAGTGGATCGATCTCACGATG
GAAGACATTAGGAGAATGGAAGACGAGACTCAGAAAGAACTAGAAACAATGCGTAAGAGGGGTTCCGTTCGAGGCACGTCGGCTGCTGAT
GTCTAGATGAGTCCCCTGTAGGGTCAGAGACAATGTCAAACTGTTTACGTAATCAAGGTCAAGTGAGGGGAACAAGCGCAGCCAGTGATG
AGTGAAGAAGAATCTGACCAGTATCTTGCAGTGTTGACGTTTCCCAGATGTGTGCTTGTGATGATACACACACATGCACAGGTTCTCAAC
CACGTGTGTATATATGTATGTGTGCATATGTCTGTAGCTGTATATAAAGCGCATGTAGAGCTACAGATCCAGATACACACACTTGTGTAT
ATATGTACATACAGACATACTGAAGGGATTAGTACAATTTCTCCAAAGTACTGTACCTATCTTCAGCAAGAATGCAAAAGAAAATATTTT
CAATATATATACCTGGAACAGATTTTAATAATTATCAGAGTAATACCATTAATGGACAAATTGACTGCAATGTAATACTAGCTGGTATGT
TTCATAAATGTCAAGCTGTGGACCAACATATATAGCCTTTTATTATTTTTCTCTTCTTTTAAGTCAGTCTGTTATAAATTTTTTTTTAGT
CCCATAAGCAGTAGACTCCCACAGAAAATTTCTTCAAAATTTTTTGGTGTTCCAATGAATCTGGGATGTAAACTCTGAATGTATTTATAA
CTATTTATTTCTGGATGGTCATTATCTTGTAGCCAAATTTGACAATATAAAGTAAGGAGCAAAGTTACAGGCCAGTTTTTACTTGTTTGC
CCTGAGGGAAAAATCCTTTTAAAAAAAATTTCTGGTTTTTATTGGATTTTTGTATTTTAAATTTCAAATATTTTTCTACATCAAACCTAG
CAAAAATGGAGATGACGGTTTCTGATTTATAATAAATACTAGACAGTTTTCAGGCTCCTGTTAGACAAACACATTGATGAAGAAATTAGT
CTTAATAGGATTGTAGGCTGTGTAGAAAAGTTGGAAATATAGCACTTCATGGAGTCTTGTTTTGAAGATGACAGTTTTCTGTAACTACAG
CTTGGAAACTATGCAAATGGTCTAGATTCCTCAGAGCTCACATGATAGGATATAGTTAGTGATGACATTTTGCTCTTCTTGTGGGAACAC
ACACTTCAAGGAGGAGATAGTGACTTTGAGATAGGAACAGTTTAAGATGCAGTGTGAGTCTGGCCTGCGTGCGGTGAGGAGGCCCCGCCA
AGAGACTGGTGGACATCTGACTGTGGGATGTGCTCTCAAGTAGGACGTCATCAGGACAGATTCTGAATAGGCATCATGAGAGTGCTGGTC
AGAAACGGCTGCCACTTTTTTTAATTTAATTTTATTTTTTATTTAAAGGAAGGAACAATAGCTAGGTAAGATTTTTATCAGCTTTCTCTG
TCTGAATCCAGTTTTTCCTCTGTCAGTCCTGGAAGCTTGAATAGAATTATATTGTTGAAGCCTTCAGGTCACAAACTGTCTTTTGTAACC
TCCTGTCCCTCCTAAAACACGCCAACCCCTGCAGTCAAATCACATTAGTAATCTGATTTGCTGACAGTCCTGCCCTGCCTGCTCCTCGTT
TTCCCACATGTCCTGCATCCCTCCCCCACTGGAGTGATTTCAGTGAATCAGACAAGGAAGGATGTGTAGGATCACTACTGCATTGCAATA
CCCTGTTATCCTCAGCAACAAAACCCACATTTCATACATCCTTTGTGTACTCAGGATAAAGACTGATGTTTACTCTCTGGGCACTGTTGT
AAGATAGGTTTTGTCAGAGCATAATCATTGTCTGCAAAGTGTTTGGTGCGAGGAAGATTATTGCTAATTTTGTGAAATAAAGAGTCTAGC
CCTCTCCTTTTAATGAACTTAACTCTCGCTGGCATCTGTAGTATCATTGGGAGCTTAGGCGCACATGGAAATGAGAGCCCGGCGCATGGA
TTTTAATGTTTTTCTAACAACTGTGGAGATTTGAGGGAATGTGTGGTGAATGTAAAATACCTAGTTTACTTGCCAGTCTCTTGTGTAAAT

>98331_98331_8_VPS13D-PITPNB_VPS13D_chr1_12476754_ENST00000543766_PITPNB_chr22_28254502_ENST00000335272_length(amino acids)=151AA_BP=94
MRGEKLSKALKSTLGFPLIRFEDAVINLDPFTRVHPYETKEFIINDILKHFQEFLGNPMGLLNDVSEGVTGLIKYGNVGGLIRNVTHGVS

--------------------------------------------------------------
>98331_98331_9_VPS13D-PITPNB_VPS13D_chr1_12476754_ENST00000543766_PITPNB_chr22_28254502_ENST00000455418_length(transcript)=2486nt_BP=285nt
ATGAGAGGAGAGAAACTCAGTAAGGCCCTAAAAAGCACCTTGGGGTTTCCTTTGATACGGTTTGAAGACGCTGTGATTAATCTAGATCCA
TTCACTCGGGTACATCCCTATGAGACCAAGGAGTTCATCATCAATGATATCCTCAAACATTTCCAGGAGTTTCTTGGCAATCCTATGGGG
CTTTTGAATGATGTTTCTGAAGGGGTTACTGGACTGATAAAATATGGAAATGTCGGGGGCCTCATCAGAAATGTTACACACGGAGTATCA
AACTCTGCTGCCAAGCAAGAAAAACGGATATTTACAAACTTCCATCGCCAGCTTTTTTGTTGGATTGACAAGTGGATCGATCTCACGATG
GAAGACATTAGGAGAATGGAAGACGAGACTCAGAAAGAACTAGAAACAATGCGTAAGAGGGGTTCCGTTCGAGGCACGTCGGCTGCTGAT
GTCTAGATGAGTCCCCTGTAGGGTCAGAGACAATGTCAAACTGTTTACGTAATCAAGGTCAAGTGAGGGGAACAAGCGCAGCCAGTGATG
AGTGAAGAAGAATCTGACCAGTATCTTGCAGTGTTGACGTTTCCCAGATGTGTGCTTGTGATGATACACACACATGCACAGGTTCTCAAC
CACGTGTGTATATATGTATGTGTGCATATGTCTGTAGCTGTATATAAAGCGCATGTAGAGCTACAGATCCAGATACACACACTTGTGTAT
ATATGTACATACAGACATACTGAAGGGATTAGTACAATTTCTCCAAAGTACTGTACCTATCTTCAGCAAGAATGCAAAAGAAAATATTTT
CAATATATATACCTGGAACAGATTTTAATAATTATCAGAGTAATACCATTAATGGACAAATTGACTGCAATGTAATACTAGCTGGTATGT
TTCATAAATGTCAAGCTGTGGACCAACATATATAGCCTTTTATTATTTTTCTCTTCTTTTAAGTCAGTCTGTTATAAATTTTTTTTTAGT
CCCATAAGCAGTAGACTCCCACAGAAAATTTCTTCAAAATTTTTTGGTGTTCCAATGAATCTGGGATGTAAACTCTGAATGTATTTATAA
CTATTTATTTCTGGATGGTCATTATCTTGTAGCCAAATTTGACAATATAAAGTAAGGAGCAAAGTTACAGGCCAGTTTTTACTTGTTTGC
CCTGAGGGAAAAATCCTTTTAAAAAAAATTTCTGGTTTTTATTGGATTTTTGTATTTTAAATTTCAAATATTTTTCTACATCAAACCTAG
CAAAAATGGAGATGACGGTTTCTGATTTATAATAAATACTAGACAGTTTTCAGGCTCCTGTTAGACAAACACATTGATGAAGAAATTAGT
CTTAATAGGATTGTAGGCTGTGTAGAAAAGTTGGAAATATAGCACTTCATGGAGTCTTGTTTTGAAGATGACAGTTTTCTGTAACTACAG
CTTGGAAACTATGCAAATGGTCTAGATTCCTCAGAGCTCACATGATAGGATATAGTTAGTGATGACATTTTGCTCTTCTTGTGGGAACAC
ACACTTCAAGGAGGAGATAGTGACTTTGAGATAGGAACAGTTTAAGATGCAGTGTGAGTCTGGCCTGCGTGCGGTGAGGAGGCCCCGCCA
AGAGACTGGTGGACATCTGACTGTGGGATGTGCTCTCAAGTAGGACGTCATCAGGACAGATTCTGAATAGGCATCATGAGAGTGCTGGTC
AGAAACGGCTGCCACTTTTTTTAATTTAATTTTATTTTTTATTTAAAGGAAGGAACAATAGCTAGGTAAGATTTTTATCAGCTTTCTCTG
TCTGAATCCAGTTTTTCCTCTGTCAGTCCTGGAAGCTTGAATAGAATTATATTGTTGAAGCCTTCAGGTCACAAACTGTCTTTTGTAACC
TCCTGTCCCTCCTAAAACACGCCAACCCCTGCAGTCAAATCACATTAGTAATCTGATTTGCTGACAGTCCTGCCCTGCCTGCTCCTCGTT
TTCCCACATGTCCTGCATCCCTCCCCCACTGGAGTGATTTCAGTGAATCAGACAAGGAAGGATGTGTAGGATCACTACTGCATTGCAATA
CCCTGTTATCCTCAGCAACAAAACCCACATTTCATACATCCTTTGTGTACTCAGGATAAAGACTGATGTTTACTCTCTGGGCACTGTTGT
AAGATAGGTTTTGTCAGAGCATAATCATTGTCTGCAAAGTGTTTGGTGCGAGGAAGATTATTGCTAATTTTGTGAAATAAAGAGTCTAGC
CCTCTCCTTTTAATGAACTTAACTCTCGCTGGCATCTGTAGTATCATTGGGAGCTTAGGCGCACATGGAAATGAGAGCCCGGCGCATGGA
TTTTAATGTTTTTCTAACAACTGTGGAGATTTGAGGGAATGTGTGGTGAATGTAAAATACCTAGTTTACTTGCCAGTCTCTTGTGTAAAT

>98331_98331_9_VPS13D-PITPNB_VPS13D_chr1_12476754_ENST00000543766_PITPNB_chr22_28254502_ENST00000455418_length(amino acids)=151AA_BP=94
MRGEKLSKALKSTLGFPLIRFEDAVINLDPFTRVHPYETKEFIINDILKHFQEFLGNPMGLLNDVSEGVTGLIKYGNVGGLIRNVTHGVS

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Fusion Gene PPI Analysis for VPS13D-PITPNB

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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Related Drugs for VPS13D-PITPNB

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for VPS13D-PITPNB

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source