|
||||||
|
 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:VPS41-CEP41 (FusionGDB2 ID:98431) |
Fusion Gene Summary for VPS41-CEP41 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: VPS41-CEP41 | Fusion gene ID: 98431 | Hgene | Tgene | Gene symbol | VPS41 | CEP41 | Gene ID | 27072 | 95681 |
| Gene name | VPS41 subunit of HOPS complex | centrosomal protein 41 | |
| Synonyms | HVPS41|HVSP41|hVps41p | JBTS15|TSGA14 | |
| Cytomap | 7p14.1 | 7q32.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | vacuolar protein sorting-associated protein 41 homologS53VPS41, HOPS complex subunitvacuolar assembly protein 41vacuolar protein sorting 41 homolog | centrosomal protein of 41 kDacentrosomal protein 41 kDacentrosomal protein 41kDatestis specific protein A14testis specific, 14testis-specific gene A14 protein | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | . | Q9BYV8 | |
| Ensembl transtripts involved in fusion gene | ENST00000310301, ENST00000395969, ENST00000466017, | ENST00000495702, ENST00000223208, ENST00000343969, ENST00000489512, ENST00000541543, | |
| Fusion gene scores | * DoF score | 15 X 14 X 9=1890 | 5 X 4 X 5=100 |
| # samples | 17 | 6 | |
| ** MAII score | log2(17/1890*10)=-3.47477958297073 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(6/100*10)=-0.736965594166206 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: VPS41 [Title/Abstract] AND CEP41 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | VPS41(38794302)-CEP41(130067859), # samples:2 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene breakpoints across VPS41 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
 |
| Fusion gene breakpoints across CEP41 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
 |
| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | ACC | TCGA-OR-A5KZ-01A | VPS41 | chr7 | 38794302 | - | CEP41 | chr7 | 130067859 | - |
Top |
Fusion Gene ORF analysis for VPS41-CEP41 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-5UTR | ENST00000310301 | ENST00000495702 | VPS41 | chr7 | 38794302 | - | CEP41 | chr7 | 130067859 | - |
| 5CDS-5UTR | ENST00000395969 | ENST00000495702 | VPS41 | chr7 | 38794302 | - | CEP41 | chr7 | 130067859 | - |
| In-frame | ENST00000310301 | ENST00000223208 | VPS41 | chr7 | 38794302 | - | CEP41 | chr7 | 130067859 | - |
| In-frame | ENST00000310301 | ENST00000343969 | VPS41 | chr7 | 38794302 | - | CEP41 | chr7 | 130067859 | - |
| In-frame | ENST00000310301 | ENST00000489512 | VPS41 | chr7 | 38794302 | - | CEP41 | chr7 | 130067859 | - |
| In-frame | ENST00000310301 | ENST00000541543 | VPS41 | chr7 | 38794302 | - | CEP41 | chr7 | 130067859 | - |
| In-frame | ENST00000395969 | ENST00000223208 | VPS41 | chr7 | 38794302 | - | CEP41 | chr7 | 130067859 | - |
| In-frame | ENST00000395969 | ENST00000343969 | VPS41 | chr7 | 38794302 | - | CEP41 | chr7 | 130067859 | - |
| In-frame | ENST00000395969 | ENST00000489512 | VPS41 | chr7 | 38794302 | - | CEP41 | chr7 | 130067859 | - |
| In-frame | ENST00000395969 | ENST00000541543 | VPS41 | chr7 | 38794302 | - | CEP41 | chr7 | 130067859 | - |
| intron-3CDS | ENST00000466017 | ENST00000223208 | VPS41 | chr7 | 38794302 | - | CEP41 | chr7 | 130067859 | - |
| intron-3CDS | ENST00000466017 | ENST00000343969 | VPS41 | chr7 | 38794302 | - | CEP41 | chr7 | 130067859 | - |
| intron-3CDS | ENST00000466017 | ENST00000489512 | VPS41 | chr7 | 38794302 | - | CEP41 | chr7 | 130067859 | - |
| intron-3CDS | ENST00000466017 | ENST00000541543 | VPS41 | chr7 | 38794302 | - | CEP41 | chr7 | 130067859 | - |
| intron-5UTR | ENST00000466017 | ENST00000495702 | VPS41 | chr7 | 38794302 | - | CEP41 | chr7 | 130067859 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000310301 | VPS41 | chr7 | 38794302 | - | ENST00000223208 | CEP41 | chr7 | 130067859 | - | 8052 | 1843 | 55 | 2931 | 958 |
| ENST00000310301 | VPS41 | chr7 | 38794302 | - | ENST00000541543 | CEP41 | chr7 | 130067859 | - | 3028 | 1843 | 55 | 2667 | 870 |
| ENST00000310301 | VPS41 | chr7 | 38794302 | - | ENST00000343969 | CEP41 | chr7 | 130067859 | - | 2868 | 1843 | 55 | 2715 | 886 |
| ENST00000310301 | VPS41 | chr7 | 38794302 | - | ENST00000489512 | CEP41 | chr7 | 130067859 | - | 4881 | 1843 | 55 | 1974 | 639 |
| ENST00000395969 | VPS41 | chr7 | 38794302 | - | ENST00000223208 | CEP41 | chr7 | 130067859 | - | 7922 | 1713 | 0 | 2801 | 933 |
| ENST00000395969 | VPS41 | chr7 | 38794302 | - | ENST00000541543 | CEP41 | chr7 | 130067859 | - | 2898 | 1713 | 0 | 2537 | 845 |
| ENST00000395969 | VPS41 | chr7 | 38794302 | - | ENST00000343969 | CEP41 | chr7 | 130067859 | - | 2738 | 1713 | 0 | 2585 | 861 |
| ENST00000395969 | VPS41 | chr7 | 38794302 | - | ENST00000489512 | CEP41 | chr7 | 130067859 | - | 4751 | 1713 | 0 | 1844 | 614 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000310301 | ENST00000223208 | VPS41 | chr7 | 38794302 | - | CEP41 | chr7 | 130067859 | - | 9.20E-05 | 0.999908 |
| ENST00000310301 | ENST00000541543 | VPS41 | chr7 | 38794302 | - | CEP41 | chr7 | 130067859 | - | 0.000895766 | 0.9991042 |
| ENST00000310301 | ENST00000343969 | VPS41 | chr7 | 38794302 | - | CEP41 | chr7 | 130067859 | - | 0.001194335 | 0.99880564 |
| ENST00000310301 | ENST00000489512 | VPS41 | chr7 | 38794302 | - | CEP41 | chr7 | 130067859 | - | 0.000195573 | 0.99980444 |
| ENST00000395969 | ENST00000223208 | VPS41 | chr7 | 38794302 | - | CEP41 | chr7 | 130067859 | - | 0.000106985 | 0.99989295 |
| ENST00000395969 | ENST00000541543 | VPS41 | chr7 | 38794302 | - | CEP41 | chr7 | 130067859 | - | 0.001253356 | 0.99874663 |
| ENST00000395969 | ENST00000343969 | VPS41 | chr7 | 38794302 | - | CEP41 | chr7 | 130067859 | - | 0.001635445 | 0.9983645 |
| ENST00000395969 | ENST00000489512 | VPS41 | chr7 | 38794302 | - | CEP41 | chr7 | 130067859 | - | 0.000242037 | 0.99975795 |
Top |
Fusion Genomic Features for VPS41-CEP41 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
 |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
Top |
Fusion Protein Features for VPS41-CEP41 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr7:38794302/chr7:130067859) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | CEP41 |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: Required during ciliogenesis for tubulin glutamylation in cilium. Probably acts by participating in the transport of TTLL6, a tubulin polyglutamylase, between the basal body and the cilium. {ECO:0000269|PubMed:22246503}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | VPS41 | chr7:38794302 | chr7:130067859 | ENST00000310301 | - | 21 | 29 | 18_27 | 596 | 855.0 | Compositional bias | Note=Poly-Glu |
| Tgene | CEP41 | chr7:38794302 | chr7:130067859 | ENST00000223208 | 0 | 11 | 169_266 | 11 | 374.0 | Domain | Rhodanese | |
| Tgene | CEP41 | chr7:38794302 | chr7:130067859 | ENST00000343969 | 0 | 10 | 169_266 | 11 | 302.0 | Domain | Rhodanese | |
| Tgene | CEP41 | chr7:38794302 | chr7:130067859 | ENST00000489512 | 0 | 3 | 169_266 | 11 | 55.0 | Domain | Rhodanese | |
| Tgene | CEP41 | chr7:38794302 | chr7:130067859 | ENST00000541543 | 0 | 9 | 169_266 | 11 | 286.0 | Domain | Rhodanese |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | VPS41 | chr7:38794302 | chr7:130067859 | ENST00000310301 | - | 21 | 29 | 568_712 | 596 | 855.0 | Repeat | Note=CHCR |
| Hgene | VPS41 | chr7:38794302 | chr7:130067859 | ENST00000310301 | - | 21 | 29 | 791_839 | 596 | 855.0 | Zinc finger | RING-type%3B atypical |
Top |
Fusion Gene Sequence for VPS41-CEP41 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >98431_98431_1_VPS41-CEP41_VPS41_chr7_38794302_ENST00000310301_CEP41_chr7_130067859_ENST00000223208_length(transcript)=8052nt_BP=1843nt AAGTGTGTGGTTTCCTCTTATTTCCGGGTCTGTCAGGTGACTCTCCCGTGGCGCCATGGCGGAAGCAGAGGAGCAGGAAACTGGGTCCCT TGAAGAATCTACAGATGAGTCTGAGGAAGAAGAGAGCGAAGAGGAACCCAAGCTGAAGTATGAAAGGCTTTCCAATGGGGTAACTGAAAT ACTTCAGAAGGATGCAGCTAGCTGCATGACAGTCCATGACAAGTTTTTGGCATTGGGCACACATTATGGCAAGGTTTATTTACTTGATGT CCAGGGGAACATCACTCAGAAGTTTGATGTAAGTCCTGTGAAGATAAATCAGATTAGCTTGGATGAAAGTGGAGAGCACATGGGTGTGTG TTCAGAGGATGGCAAGGTGCAGGTATTTGGACTGTATTCTGGAGAAGAATTTCACGAGACTTTTGACTGTCCCATTAAAATTATTGCTGT GCACCCACATTTCGTGAGATCCAGTTGCAAGCAGTTTGTGACCGGAGGGAAGAAGCTGCTACTGTTTGAACGGTCTTGGATGAACAGATG GAAGTCTGCTGTTCTGCATGAAGGGGAAGGGAACATAAGGAGTGTGAAGTGGAGAGGCCATCTGATTGCTTGGGCCAATAATATGGGTGT GAAGATTTTTGACATCATCTCAAAGCAAAGAATCACCAATGTGCCCCGGGATGATATAAGTCTTCGCCCAGACATGTATCCCTGCAGCCT CTGCTGGAAGGACAATGTGACACTGATTATTGGCTGGGGGACTTCTGTCAAGGTGTGCTCAGTGAAGGAACGGCATGCCAGTGAAATGAG GGATTTGCCAAGTCGATATGTTGAAATAGTGTCTCAGTTTGAAACTGAATTCTACATCAGTGGACTTGCACCTCTCTGTGATCAGCTTGT TGTACTTTCGTATGTAAAGGAGATTTCAGAAAAAACGGAAAGAGAATACTGTGCCAGGCCTAGACTGGACATCATCCAGCCACTTTCTGA GACTTGTGAAGAGATCTCTTCTGATGCTTTGACAGTCAGAGGCTTTCAGGAGAATGAATGTAGAGATTATCATTTAGAATACTCTGAAGG GGAATCACTTTTTTACATCGTGAGTCCGAGAGATGTTGTAGTGGCCAAGGAACGAGACCAAGATGATCACATTGACTGGCTCCTTGAAAA GAAGAAATATGAAGAAGCATTGATGGCAGCTGAAATTAGCCAAAAAAATATTAAAAGACATAAGATTCTGGATATTGGCTTGGCATATAT AAATCACCTGGTGGAGAGAGGAGACTATGACATAGCAGCACGCAAATGCCAGAAAATTCTTGGGAAAAATGCAGCACTCTGGGAATATGA AGTTTATAAATTTAAAGAAATTGGACAGCTTAAGGCTATTAGTCCTTATTTGCCAAGAGGTGATCCAGTTCTGAAACCACTCATCTATGA AATGATCTTACATGAATTTTTGGAGAGTGATTATGAGGGTTTTGCCACATTGATCCGAGAATGGCCTGGAGATCTGTATAATAATTCAGT CATAGTTCAAGCAGTTCGGGATCATTTGAAGAAAGATAGTCAGAACAAGACTTTACTTAAAACCCTGGCAGAATTGTACACCTATGACAA GAACTATGGCAATGCTCTGGAAATATACTTAACATTAAGACATAAAGACGTTTTTCAGTTGATCCACAAGCATAATCTTTTCAGTTCTAT CAAGGATAAAATTGTTTTATTAATGGATTTTGATTCAGAGAAAGCTGTTGACATGCTTTTGGACAATGAAGATAAAATTTCAATTAAAAA GGTAGTGGAAGAATTGGAAGACAGACCAGAGCTACAGCATGTGTATCTGATGAAAAGGATACCACAGAACCCAAGATACCAGCATATCAA ATCAAGACTGGACACTGGTAACAGTATGACTAAATATACTGAGAAGCTCGAAGAGATTAAGAAAAATTATAGATACAAAAAAGATGAGCT TTTCAAGAGACTAAAAGTTACAACTTTTGCCCAGCTGATCATCCAAGTTGCTTCCCTCTCTGATCAAACACTGGAAGTGACAGCTGAGGA GATTCAAAGGCTGGAAGACAATGATTCTGCAGCTTCAGACCCTGATGCTGAAACCACTGCCAGGACCAATGGGAAAGGAAATCCAGGTGA GCAGTCGCCGAGCCCTGAGCAGTTCATAAACAACGCAGGAGCAGGGGACTCCAGCCGCTCAACTCTTCAGAGTGTCATCAGTGGTGTTGG GGAACTGGATCTAGACAAAGGGCCAGTGAAGAAAGCAGAGCCCCATACCAAAGACAAACCTTATCCTGACTGCCCCTTCCTGCTGCTAGA TGTGCGTGATAGAGATTCTTACCAGCAGTGCCACATTGTTGGAGCTTACAGTTACCCAATTGCAACTCTGTCTAGAACAATGAACCCTTA TTCAAATGATATTCTTGAATATAAAAATGCCCATGGCAAGATCATCATTCTGTATGACGATGATGAAAGGCTGGCCAGTCAGGCGGCCAC CACCATGTGCGAGCGTGGATTTGAAAACCTCTTCATGCTTTCCGGAGGTCTAAAAGTCTTAGCTCAGAAATTCCCGGAAGGACTGATTAC TGGTTCCCTGCCAGCATCTTGCCAGCAGGCCCTTCCTCCTGGGTCTGCCCGGAAACGATCCAGCCCCAAAGGGCCACCCCTACCAGCTGA GAATAAATGGAGATTTACCCCAGAAGACTTAAAAAAGATAGAATATTATCTGGAAGAGGAGCAAGGGCCTGCAGATCATCCTAGCCGACT GAACCAAGCTAACTCCTCCGGAAGAGAGTCCAAGGTGCCTGGTGCCCGAAGCGCTCAGAATCTGCCAGGTGGCGGCCCCGCCAGCCACTC AAACCCCCGCTCCCTCAGCAGTGGTCACCTGCAAGGCAAACCCTGGAAGTAAAGACTTTGTCTCACTTAGGCAAATAAATGTTCTTCCTC TTTTCAGAACCCCTGAGCATTTCCCAAGTTGGGTCATTTCCAGAAACTTCTGCAGAGGAAAGACCATGACATATGTATGGGATAGGCCTC TTCCCTGTCCCTGTCTCCAGTTCCTCTCCCCTCAGGAGGCCACCTCAGGAAGGATTTTGACAGGTGACCATAAAAACCAGAGGTGTGACA GGCTCTAGTCTCCTCCCTGTTGTTTACAGCATATTTAAGTCTTGTGAAACTGTATAGGAAAAAAGTATCTACGTTTTTAGTTTTTTTGTT TTGTTTTTTTTTAATAAGGTCCAGCTTGTTGGGTCTCTCTGTGTTGTTTTGTAAATACTTCAGTCACATCTGCCCGTGTGCCTGTCCCTG CCACCTTTTCATTCACTGTTCTTGACTTCATGAAGGCTTCTCCGGGCAGTCTTGGTGTGAGAAGCTGTTTCCAAGGGTGCAGATGAGCCT TAGGTTCCAGCCGCCTGCAGACCCCACCCCAGCAGGCTCACTCAGCAAGGAGCTCTCTGCCCAGCATATTGCAGGCCCTGTTTTGAGTAT GGAAGCCAGTGCCTGTGTACTCACTGAAATTGAAGATGAGGAAAGTAGCTGTACACTCACTGAATGCTCCCCCTTACTAGATATTTCCTG GAGCCAGAAAGGTATGCATGTGGGTGTCTTCACACCGGGGAGGAGGGCCTCTCATGGGAAAGCCCTGGCCACCACACCGGCCTGTGCCCC TTGAAGCCCACCAAAGCGGCCCTCACTTGTGGTCAGTATATCAGTTATGACGCCCATTGCCCAGCTTCAGTCCATCCATGTTAGATGGAC AGAAATTATGGCCAGTTGAAAATACCAGCTTTGGTTGGACAACTGTGGACACACAAGGTGAAGAGGACTCCGAAGTCCTTTGTCAGGGCT GACAACCTCGTAAGCCCTTGCTTAGAAATACAGTATTAGTCTAATTGAGTAATTAGTGCAATTTCCTGCTTACTTTTCATTCTCATGACT GAACTGTGATTAGGAAGTTGTGATTATAGATTCTGGTTTTGGCCGGAATTTTGAATCAGCATTAATTGAATTGCTAAATGACTGACATTC ATTCCATTTAATTGGGGGAACAAAAGGCCTCAGGTAAGGATGAGGAACTCTGAAATCAGATGGAAAAGAGCGGTGTTAATTTTTATGGTC TGTGATCGTAGCTGTGATAAGGGACTGAGGAATAAATTGTGCTCTTTGTCATGGCAACCAGCTTCTGAAAAGCCCACTGAAAATTGCCTG TCCTGCTGGTAACTGCTACGGGGTAAGATTTGCCTTAACAGTACTATTTTCTCGCCACCAAAAAAAAAAAAAAAAAAAAAAAAAAATGCA CCACAGTATTTCTAGCATGGGGGCTGTGTTTGTATGAGAAATAAACGTAATAAATATCTCATAGAGACATATGGAAAAATAACTTTCAGA TTCAGCCCAGTTCTGTTTTAGAGTGTGTTTATTCTTCTCTACTTGATTTCCAAAGTGCAACATTTTCCGATGCTTTAGAAATCAAACAAA CCAGGGACATTGTTCAGATGTCAAGCCATGCCCAATTTTCCACAAGATTCAAGAATCTTGTATAAAATTCAGCCAACGTACACATAGCTT TAATGAGGAGCCTGTCATGTTTCCCCATAAATTTATTGCCTGAGAACTTAGTTCAGCCTTTGCTAATGCCAAAATGCTCTGGCTTTGTAT TTTCTTTACAGCATAGATAGAAAAATGCACATTTTTCCACACTCAGCTTTCCCCTAGCATGGACAAGATTTTCAGCCATTTTTGCCACAT ATACATTTTTAAGGAAAAAAGATTTTTCTCTGTAAGAAAGTTCTGGTTATGCTGTTTTAAAGGTGACTTGTCAGGAGTTGAGACTTCCCT GCCGGATTCTATTTTGAAAGTAAATGGTCTTCCCTCCTTGTTCCGATTCTGCGTTCCCATCGTCAGACAACTTTGGAGTATTAGAAACCA CTGTATATATGTGGAAAGCCAGGTCAGCCAGACCTGTTAGAATTGGTGTGCACTCACCTGAGAGATCTGGCAGGTTGGATATATTTATGT GTATTTCTCCACAGTGCTTGCTTTGCCCTGTTGGTAAGGATTTTAAATAACCATGCTCAAAAGAGCTGTTCTAATCTGCGTTTTGCATGT TAAGTGTTAATATCAAACATTCTTTACGTGCTCGAGGTATTGCTTTTAACATTCTACTTTGCCAGTTTCTTCATTAGATTAATTGACATG TATTATTTAAATGACCAGTGATGCTTTGTGCAATTATGAATGTTGAAGATTAAAGTACATAGTTACTAATTTGTCGTTTGCTATTAATAT GCTGAAAACTGCCAACTTCTCTCTTCTTTTCTGTCGAGATGATTTGGGGGAGCCACAGGAGACTGGTGTGATTTTTGCTGCATCTCCTAG GAAAGCATTTTTTAAAAAAAATAAATGAATCAGGAAATCAGTCCAATTAGGGCAGGGGGCCTCAGCTCTCCAGTCAGAAAGCCTGGATTT CTTTTCCTGCTCAGGCTGGGACTGAAGCCACCTTCAACAACTGGATCATGGCTTCCTACCAGCGTCTCAGGGGTTGACTAGCTGCCCTTG TCTGGGGCTTGTGAACCCTGAGACAGAAGGTGCTTCATCGATGTACAACTACAGCACCCTGAACAGCAGTGATGGCCAAAGTTTAAATAA TACCTTAAATGCTTTAAAGGGGTTTGTGTTTAAGGAAGGGAGAAAAGAAAAAAAGAAAGGAAGGGAGAAAGAAGCAAGGAAATGGGAAGA AGGGAGGGCAGAGAGAAGAAAAGAAGCAGAAAGCGAGAGAGAAAGGAGAAAGCTACATTACTTATTTGAAAACAAAAGGAACACCCTGGG CTGTAATAATGTCAGGCTCAATCTCTTGAAAAAGTATGGAATGATTTAAATGGCCTGCATTCATTTTATCTTTTATCTTTTTTTTTTTTT TTAACCTTTAGTGGTTAGCCAGGACCAGCACGATCATATTGGGCTTGGTATAAATCCGAATGAAAAGAGACCAAATAACATTCATTAGTT GCTCAGGGATTTTTCCTGTGGTGCTATTTAAATTATACAAAAATTCTTAAGACTTTAGGCTACTCGACCAAGAAAACAGAACAAAACAAA AAATCGTGTTTTCTCTAATTCCCTTGTGGAATGTAAGTGAAATCAGAGTCCTAGGCTAGGAAGAAATACGTAGGTAATTTTTCTTGTGTT GGTTTTGGTTTCTGTCATGTTGTTTATTGGCTATAGATTCTGTCTTTTATGTTATCTGACTTTTTTAGAGCGAATAATTAGTTTCTGTCC ACCTGGATTTAAATCCATGACCACCTTCTTGCTCTACTCTGAAGATAATCAGTAAGAACCTTTCTTTCTCCAGTTCTAAAACGTTCTCAG TGTCTTTAATGTGTGTTTATTTTCTTCCCAATTCTTTCAAAGATTTAACTCCCACGATACTTTTTTTTCCCCAGGAAACACCGCAAATGT GTGGAATATAATTCACCAGTTTAATTATGTGAGCATGTTGAGTACTTACATGCAGGTCCATTAATTTTTCACTAACAATTATTTTTTCAT GCAAAAGCAATAAATAACATTGTGCTTCCAAAATGTTCAGAATACATTTGGGTAGTAATACTTTCCTAGATTTACAATAATTATTGAAAT TATTATTATGACATCTTTAAATGGATACACAGGTCAGTTACAACATAAAAAATGTAATGGTGGAAATTTGTCAGCCTTGAATTCAGGCAG AACAGGATTCGGTGCATGATTTTATGTGTTTTCGAAACGGTGTCTGTCACATTGTGATCCCCTGATGGCTCCCCTCTCTGTTGCTGATCC TCTTTGTTCTGTACAGAAGCAAATTCTCACCTGTGTAACATCCTGAAGCACCTGGTAAAATGTGAGGCAAAGAGAGGCCACTTCTCAAAT GCTGTGGACGGATGGGCTGCATCTTTTAAAGGATATCAATATGTCTTCCTGTTGCAATTATTTTGACTATAAGCTCCCAGAGAGTGAAAA TCACCAACCCTGTGACAGTGGCCCTTAATAAGTGTTCATGAATAAATGAATTGAACCTGTCAAGATTGAAGTTTGGATGTGATGCCCACT GTGGTGGCCACTCAGTGCTAGTCTGTCATTCTGGAGACCCAGAAAGCTCGTTATCTTCTGTCCCCCTTGTGTATCCTGCCTTTGTGGGCG AGGCATTCAAAACCCTGAGGTTTTTAGATCTCCCTCTACAGGAAGTACCCAGAGAGCTGCTGGGGGTGTTATTACCCTGTCTCTGCCAGG CTTAAAGTATCCTCCCAAATTCAGCACGCAAAGGTCACACACCACCCCCATCTTAAGAGTAGGTTTTCTCTTTTGTTTCAAATCTTGAAG ATTTCCAGAAAATAATAATACTAGCCAATGTTTGTGGAGAGCTTACTTTGCTCCTAGATTCTTCATTATATGTTTTGACCCATTTAATTT CCACAACAGTCTGATGAGGCAGGCACCCCCATTTTCAGATGAGGAGACTGAGGTTCGGGTAGAAATTAAGTGACTCAGGTTTGCCTTCAG TCTCTGACCAAGGGTTTGAAAAGCCAGGAGCCAGCCTGAGAACTGTGGCTCCAGAGGGTGTTCTTTCAGCCACTCCGCTCTATGCTTCTC ACTCTGGGTGGGCACAACCATGTTCTCCTTTGGTGATGCCTCTAACTTACCGTGAAAATGTACCTTTCCCTTCGCTATTGGCTTCCCTTC CCTCCTAGTCAGCCGAGATTCTTTTGAAAACTTTCCTCCGCTTGCCTGCACAAAAGGCGATGGAAATTCAGGAACTGAAACATCTGCTCT GGGGAATGCGTATTTCCACATTTCCACCGCCTGTGTCTGCTGTCTTATCTTGAAGACAGGTGCTCCAGGGCTTCCGAGGTTATTTTGTCT GTTAATGGACACCTTGCAAAGTACCACTTAAGGAATGAGAATTACAAACTTTTAATTATATTGTAGGGGGAAAAAAGTAGGCTGTTTTCC >98431_98431_1_VPS41-CEP41_VPS41_chr7_38794302_ENST00000310301_CEP41_chr7_130067859_ENST00000223208_length(amino acids)=958AA_BP=596 MAEAEEQETGSLEESTDESEEEESEEEPKLKYERLSNGVTEILQKDAASCMTVHDKFLALGTHYGKVYLLDVQGNITQKFDVSPVKINQI SLDESGEHMGVCSEDGKVQVFGLYSGEEFHETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGEGNIRSVKWR GHLIAWANNMGVKIFDIISKQRITNVPRDDISLRPDMYPCSLCWKDNVTLIIGWGTSVKVCSVKERHASEMRDLPSRYVEIVSQFETEFY ISGLAPLCDQLVVLSYVKEISEKTEREYCARPRLDIIQPLSETCEEISSDALTVRGFQENECRDYHLEYSEGESLFYIVSPRDVVVAKER DQDDHIDWLLEKKKYEEALMAAEISQKNIKRHKILDIGLAYINHLVERGDYDIAARKCQKILGKNAALWEYEVYKFKEIGQLKAISPYLP RGDPVLKPLIYEMILHEFLESDYEGFATLIREWPGDLYNNSVIVQAVRDHLKKDSQNKTLLKTLAELYTYDKNYGNALEIYLTLRHKDVF QLIHKHNLFSSIKDKIVLLMDFDSEKAVDMLLDNEDKISIKKVVEELEDRPELQHVYLMKRIPQNPRYQHIKSRLDTGNSMTKYTEKLEE IKKNYRYKKDELFKRLKVTTFAQLIIQVASLSDQTLEVTAEEIQRLEDNDSAASDPDAETTARTNGKGNPGEQSPSPEQFINNAGAGDSS RSTLQSVISGVGELDLDKGPVKKAEPHTKDKPYPDCPFLLLDVRDRDSYQQCHIVGAYSYPIATLSRTMNPYSNDILEYKNAHGKIIILY DDDERLASQAATTMCERGFENLFMLSGGLKVLAQKFPEGLITGSLPASCQQALPPGSARKRSSPKGPPLPAENKWRFTPEDLKKIEYYLE -------------------------------------------------------------- >98431_98431_2_VPS41-CEP41_VPS41_chr7_38794302_ENST00000310301_CEP41_chr7_130067859_ENST00000343969_length(transcript)=2868nt_BP=1843nt AAGTGTGTGGTTTCCTCTTATTTCCGGGTCTGTCAGGTGACTCTCCCGTGGCGCCATGGCGGAAGCAGAGGAGCAGGAAACTGGGTCCCT TGAAGAATCTACAGATGAGTCTGAGGAAGAAGAGAGCGAAGAGGAACCCAAGCTGAAGTATGAAAGGCTTTCCAATGGGGTAACTGAAAT ACTTCAGAAGGATGCAGCTAGCTGCATGACAGTCCATGACAAGTTTTTGGCATTGGGCACACATTATGGCAAGGTTTATTTACTTGATGT CCAGGGGAACATCACTCAGAAGTTTGATGTAAGTCCTGTGAAGATAAATCAGATTAGCTTGGATGAAAGTGGAGAGCACATGGGTGTGTG TTCAGAGGATGGCAAGGTGCAGGTATTTGGACTGTATTCTGGAGAAGAATTTCACGAGACTTTTGACTGTCCCATTAAAATTATTGCTGT GCACCCACATTTCGTGAGATCCAGTTGCAAGCAGTTTGTGACCGGAGGGAAGAAGCTGCTACTGTTTGAACGGTCTTGGATGAACAGATG GAAGTCTGCTGTTCTGCATGAAGGGGAAGGGAACATAAGGAGTGTGAAGTGGAGAGGCCATCTGATTGCTTGGGCCAATAATATGGGTGT GAAGATTTTTGACATCATCTCAAAGCAAAGAATCACCAATGTGCCCCGGGATGATATAAGTCTTCGCCCAGACATGTATCCCTGCAGCCT CTGCTGGAAGGACAATGTGACACTGATTATTGGCTGGGGGACTTCTGTCAAGGTGTGCTCAGTGAAGGAACGGCATGCCAGTGAAATGAG GGATTTGCCAAGTCGATATGTTGAAATAGTGTCTCAGTTTGAAACTGAATTCTACATCAGTGGACTTGCACCTCTCTGTGATCAGCTTGT TGTACTTTCGTATGTAAAGGAGATTTCAGAAAAAACGGAAAGAGAATACTGTGCCAGGCCTAGACTGGACATCATCCAGCCACTTTCTGA GACTTGTGAAGAGATCTCTTCTGATGCTTTGACAGTCAGAGGCTTTCAGGAGAATGAATGTAGAGATTATCATTTAGAATACTCTGAAGG GGAATCACTTTTTTACATCGTGAGTCCGAGAGATGTTGTAGTGGCCAAGGAACGAGACCAAGATGATCACATTGACTGGCTCCTTGAAAA GAAGAAATATGAAGAAGCATTGATGGCAGCTGAAATTAGCCAAAAAAATATTAAAAGACATAAGATTCTGGATATTGGCTTGGCATATAT AAATCACCTGGTGGAGAGAGGAGACTATGACATAGCAGCACGCAAATGCCAGAAAATTCTTGGGAAAAATGCAGCACTCTGGGAATATGA AGTTTATAAATTTAAAGAAATTGGACAGCTTAAGGCTATTAGTCCTTATTTGCCAAGAGGTGATCCAGTTCTGAAACCACTCATCTATGA AATGATCTTACATGAATTTTTGGAGAGTGATTATGAGGGTTTTGCCACATTGATCCGAGAATGGCCTGGAGATCTGTATAATAATTCAGT CATAGTTCAAGCAGTTCGGGATCATTTGAAGAAAGATAGTCAGAACAAGACTTTACTTAAAACCCTGGCAGAATTGTACACCTATGACAA GAACTATGGCAATGCTCTGGAAATATACTTAACATTAAGACATAAAGACGTTTTTCAGTTGATCCACAAGCATAATCTTTTCAGTTCTAT CAAGGATAAAATTGTTTTATTAATGGATTTTGATTCAGAGAAAGCTGTTGACATGCTTTTGGACAATGAAGATAAAATTTCAATTAAAAA GGTAGTGGAAGAATTGGAAGACAGACCAGAGCTACAGCATGTGTATCTGATGAAAAGGATACCACAGAACCCAAGATACCAGCATATCAA ATCAAGACTGGACACTGGTAACAGTATGACTAAATATACTGAGAAGCTCGAAGAGATTAAGAAAAATTATAGATACAAAAAAGATGAGCT TTTCAAGAGACTAAAAGTTACAACTTTTGCCCAGCTGATCATCCAAGTTGCTTCCCTCTCTGATCAAACACTGGAAGTGACAGCTGAGGA GATTCAAAGGCTGGAAGACAATGATTCTGCAGCTTCAGACCCTGATGCTGAAACCACTGCCAGGACCAATGGGAAAGGAAATCCAGGTGA GCAGTCGCCGAGCCCTGAGCAGTTCATAAACAACGCAGGAGCAGGGGACTCCAGCCGCTCAACTCTTCAGAGTGTCATCAGTGGTGTTGG GGAACTGGATCTAGACAAAGGGCCAGTGAAGAAAGCAGAGCCCCATACCAAAGACAAACCTTATCCTGACTGCCCCTTCCTGCTGCTAGA TGTGCGTGATAGAGATTCTTACCAGCAGTGCCACATTGTTGGAGCTTACAGTTACCCAATTGCAACTCTGTCTAGAACAATGAACCCTTA TTCAAATGATATTCTTGAATATAAAAATGCCCATGGCAAGATCATCATTCTGTATGACGATGATGAAAGGCTGGCCAGTCAGGCGGCCAC CACCATGTGCGAGCGTGGATTTGAAAACCTCTTCATGCTTTCCGGAGGCCGACTGAACCAAGCTAACTCCTCCGGAAGAGAGTCCAAGGT GCCTGGTGCCCGAAGCGCTCAGAATCTGCCAGGTGGCGGCCCCGCCAGCCACTCAAACCCCCGCTCCCTCAGCAGTGGTCACCTGCAAGG CAAACCCTGGAAGTAAAGACTTTGTCTCACTTAGGCAAATAAATGTTCTTCCTCTTTTCAGAACCCCTGAGCATTTCCCAAGTTGGGTCA >98431_98431_2_VPS41-CEP41_VPS41_chr7_38794302_ENST00000310301_CEP41_chr7_130067859_ENST00000343969_length(amino acids)=886AA_BP=596 MAEAEEQETGSLEESTDESEEEESEEEPKLKYERLSNGVTEILQKDAASCMTVHDKFLALGTHYGKVYLLDVQGNITQKFDVSPVKINQI SLDESGEHMGVCSEDGKVQVFGLYSGEEFHETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGEGNIRSVKWR GHLIAWANNMGVKIFDIISKQRITNVPRDDISLRPDMYPCSLCWKDNVTLIIGWGTSVKVCSVKERHASEMRDLPSRYVEIVSQFETEFY ISGLAPLCDQLVVLSYVKEISEKTEREYCARPRLDIIQPLSETCEEISSDALTVRGFQENECRDYHLEYSEGESLFYIVSPRDVVVAKER DQDDHIDWLLEKKKYEEALMAAEISQKNIKRHKILDIGLAYINHLVERGDYDIAARKCQKILGKNAALWEYEVYKFKEIGQLKAISPYLP RGDPVLKPLIYEMILHEFLESDYEGFATLIREWPGDLYNNSVIVQAVRDHLKKDSQNKTLLKTLAELYTYDKNYGNALEIYLTLRHKDVF QLIHKHNLFSSIKDKIVLLMDFDSEKAVDMLLDNEDKISIKKVVEELEDRPELQHVYLMKRIPQNPRYQHIKSRLDTGNSMTKYTEKLEE IKKNYRYKKDELFKRLKVTTFAQLIIQVASLSDQTLEVTAEEIQRLEDNDSAASDPDAETTARTNGKGNPGEQSPSPEQFINNAGAGDSS RSTLQSVISGVGELDLDKGPVKKAEPHTKDKPYPDCPFLLLDVRDRDSYQQCHIVGAYSYPIATLSRTMNPYSNDILEYKNAHGKIIILY -------------------------------------------------------------- >98431_98431_3_VPS41-CEP41_VPS41_chr7_38794302_ENST00000310301_CEP41_chr7_130067859_ENST00000489512_length(transcript)=4881nt_BP=1843nt AAGTGTGTGGTTTCCTCTTATTTCCGGGTCTGTCAGGTGACTCTCCCGTGGCGCCATGGCGGAAGCAGAGGAGCAGGAAACTGGGTCCCT TGAAGAATCTACAGATGAGTCTGAGGAAGAAGAGAGCGAAGAGGAACCCAAGCTGAAGTATGAAAGGCTTTCCAATGGGGTAACTGAAAT ACTTCAGAAGGATGCAGCTAGCTGCATGACAGTCCATGACAAGTTTTTGGCATTGGGCACACATTATGGCAAGGTTTATTTACTTGATGT CCAGGGGAACATCACTCAGAAGTTTGATGTAAGTCCTGTGAAGATAAATCAGATTAGCTTGGATGAAAGTGGAGAGCACATGGGTGTGTG TTCAGAGGATGGCAAGGTGCAGGTATTTGGACTGTATTCTGGAGAAGAATTTCACGAGACTTTTGACTGTCCCATTAAAATTATTGCTGT GCACCCACATTTCGTGAGATCCAGTTGCAAGCAGTTTGTGACCGGAGGGAAGAAGCTGCTACTGTTTGAACGGTCTTGGATGAACAGATG GAAGTCTGCTGTTCTGCATGAAGGGGAAGGGAACATAAGGAGTGTGAAGTGGAGAGGCCATCTGATTGCTTGGGCCAATAATATGGGTGT GAAGATTTTTGACATCATCTCAAAGCAAAGAATCACCAATGTGCCCCGGGATGATATAAGTCTTCGCCCAGACATGTATCCCTGCAGCCT CTGCTGGAAGGACAATGTGACACTGATTATTGGCTGGGGGACTTCTGTCAAGGTGTGCTCAGTGAAGGAACGGCATGCCAGTGAAATGAG GGATTTGCCAAGTCGATATGTTGAAATAGTGTCTCAGTTTGAAACTGAATTCTACATCAGTGGACTTGCACCTCTCTGTGATCAGCTTGT TGTACTTTCGTATGTAAAGGAGATTTCAGAAAAAACGGAAAGAGAATACTGTGCCAGGCCTAGACTGGACATCATCCAGCCACTTTCTGA GACTTGTGAAGAGATCTCTTCTGATGCTTTGACAGTCAGAGGCTTTCAGGAGAATGAATGTAGAGATTATCATTTAGAATACTCTGAAGG GGAATCACTTTTTTACATCGTGAGTCCGAGAGATGTTGTAGTGGCCAAGGAACGAGACCAAGATGATCACATTGACTGGCTCCTTGAAAA GAAGAAATATGAAGAAGCATTGATGGCAGCTGAAATTAGCCAAAAAAATATTAAAAGACATAAGATTCTGGATATTGGCTTGGCATATAT AAATCACCTGGTGGAGAGAGGAGACTATGACATAGCAGCACGCAAATGCCAGAAAATTCTTGGGAAAAATGCAGCACTCTGGGAATATGA AGTTTATAAATTTAAAGAAATTGGACAGCTTAAGGCTATTAGTCCTTATTTGCCAAGAGGTGATCCAGTTCTGAAACCACTCATCTATGA AATGATCTTACATGAATTTTTGGAGAGTGATTATGAGGGTTTTGCCACATTGATCCGAGAATGGCCTGGAGATCTGTATAATAATTCAGT CATAGTTCAAGCAGTTCGGGATCATTTGAAGAAAGATAGTCAGAACAAGACTTTACTTAAAACCCTGGCAGAATTGTACACCTATGACAA GAACTATGGCAATGCTCTGGAAATATACTTAACATTAAGACATAAAGACGTTTTTCAGTTGATCCACAAGCATAATCTTTTCAGTTCTAT CAAGGATAAAATTGTTTTATTAATGGATTTTGATTCAGAGAAAGCTGTTGACATGCTTTTGGACAATGAAGATAAAATTTCAATTAAAAA GGTAGTGGAAGAATTGGAAGACAGACCAGAGCTACAGCATGTGTATCTGATGAAAAGGATACCACAGAACCCAAGATACCAGCATATCAA ATCAAGACTGGACACTGGTGCCTGTGTGTATCTTACCAGCTCCCCAGCACTGCCAGACTGTGCCATGAATGGATTATGCTTCTGATGAAA TCCCTGGCTGCGTTTTGTTCAGTCACCACCGCAGGGTTCTTGTATATTCTCAAGCACCCTCTCTGGGTTTCTGTTTTGCAGCACTGCAGG CTGATTAAGGGACACTTTCCAAACCACAGGGCTCTCCCTTTATTAGTCCCCACAGTCTTTCATTGGCTGCATTGTCCTCCCATTTCTATC TATATTCAATCTAATTTCCAATTTCTTTAGCTTTCTGAAATTCTGTAGGCTTTCTCCACTCAGTCTTTTCTAGCCTTATTTTTGTCTTTT TAAAAATTCACCTTCCTTTTATTATCTCTAGACAAACTATTCATTCCCTCTTTTCTTCTTTAGGCTTTACTTTTCCTGAATATTTGCTAA TAGCCTTGACTGTAAGCATCAAACTCATTATAGACTAGGTACTCTTCATTTTTATTTGTTGTTTAATTCTGTTTCTTCCGTCAAAGGAAG AAATATATGTGAAAGGCTTTTATAAACCAGAAAGCACTATACACACATATCACTTATTGAGGTTAACAAAGGACCACTGTGCCTCTTTTC ATGCTTTCTGCTCTTCCAAGCCAAGAGAACTTCTCCATAGAGGAGGGAAATATTGAAGAAAAATAAAGCCATGGAGTTGTCTCTTAGCAA CTGAGTTCGTGCCTTATAAATCTCATCTACTTTAGATTACTGCTGCACAAAATCACTTGCTTTTCTTATTGGCTCAGTATAAATAATGTT ATTAAATTATAGGAAAACAATGGAAAAAATCTAATGAATGACTCATTCACTGAATCAGTTGCACTCTGTGTTTGCACAGCACTGTTGCTA TAGTCGGGTTGTTTCTTCCTCTTGATTCTAATTGTAAAGTTTTGTTATATATCTTTTATCACAACTTTAGTTGTAAGTAAACAAAGTAGA AGCTAAATGCTACCTTATACATTTATAGGTTGCTTAAGTCGTGAAGCAATATGAGTCATATATGTAGCACATAACATATACTGTATATAA GTCAAGTTGTACATAGTTTAAAGAAAATCAGGTGTGCAGAAACTCAGACCAAATTGGGAAGTATTTGCATTATAAAATAACTCATTATAA GGATTTTTCAGTTAGTAGATCTCCATAGTAAATTTCATTCAGCAAATGTGTATTTTTCCTATTTATTTATTTATTTATTTATTGAGATGA AGTCTCGCTCTGTTGCCCAAGCTGGAGTGCAGTGGCGTGATCTTGGCTCACTGCAACCTCTGCCTCCCAGGTTCAAGCGATTCTTCTGCC TCAGCCTCCTGAGTAGCTGGGACTACAGGTGCGCACCACCATGCCTGGCTAATTTTTATATTTTTAGTAGAGACGGGGTTTTACTATGTT GGTCAGGCTGGTCTCGAACTCCTGACCTTGTGATCCTCCCGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACTGTGCCAG GTCTAGTTATTTATTTATTTATTGTAGAGATGGGCTCTCACTGTGTTGGCCAGGGTGGTCTTGAACTCCTGGCCTCGAGCAATCCTTCCA CCTCAGTCTCCCAAAGTGCTGGGATTACAGGTGTGAGCTATCACACCTGGCCATTTTTTTTTTTTTTTTTTTTTTTGAGATAGAGTCTCA CTCTGTCACCCGCATTGTAGTGCAGTGGCGCATTCTTGCTCACTGCAACCTCCCCTTCCTGGGCTCAGGGGATCCTCCTACCTCAGCCTC TCAAGTAGCTGGGACTACAGGGATGTGCCACCATGCCTGGCTAGTTTTTGTGTATGTGTGTGTTTTGTAGAGACGAGGTCTCACTATTTT GCCCAGGCTGGTCCGGAACTCCTGGGCTCAAGCAATCCTGCCTCCTCAGCCTCCCAACGTGCTGGGATTGCAGGCATGATCCAGTGCACC TGACCATCATTCAGCAAGTATTTTTGAGTGTCTCCTATGCTAGACAATGGAAGGGATAAAGATTATTCATACGTGTGTGTGTGTGTGTGT GTGTACGTGCCCATAAATAGTCCTTGGCTTTCTGTCTAGTAAGGTAGGTAAGACAATACAGTGATAAATGCCTTGTGAGTTGTAAGCCGA GTGCTATAGAGGCTCAGAGGAGGGAAAGGTCACTTCCTGCTGAGTGAGCTCTTACGAGTATGTGGCAAGGTGATACGTTAGAGAATGCAA GACTAAGAGTTTGTCAAGTTAAGTAATTAAGGCAACATTAAGAGGTAGTGAGTTGGTGTCCAGTGCTAGAGCAAGGAGTTTCAGCTTTAG TTAGGAAGCAATGGGGAGCCACTGACTTTTTTTTTTCTTTTTGATCAAAAAGTCTTATCTGGGAAAATGTATCTGGCAGTAATGTGTAAT TTCAATTTTTTTTAAAAAAAATTGGTTCTTGGATAGTCTTTTAGGCTTCTTTTGTATGAAACAAAGCCATGTTTATAAATAAGTGAATTA TGAAATGGATTCATTTCCAATCTTTTTAAAAGGTAGTCAGAAACTATCTTCAGATGCAATTAGATACAGTAAGATAGGCTGCATAGTTAA GATGTAAGCAGTTTACACAGTGGGATAAAAATGCTACTTTTCATACTTTCTCAAACCATTTTTAGGGGTATTTTTGTGTCAGCCATCCTG CTATCTCATTTGTCCAATTAAAGCAAGGAAGAAATCCTCCATTCTCCTTTTTTCCCCATTCTTGGATAGAATGAATGTCTATAGTGAAAA GAACTCATCAGTAGTCCTCTCAGATTTGGTCTGAATTTCACCAAATATTTGTATAATTGCAAAAAACTTGTTTCTCAGCCTTCTCCTTTA GGGGGAAAACAAATAGAGGGCATGATGGCCTACCTCCCTGCATTGTGGTGAGGGTCAGCTGATACAAAATAAAGTGTTAAGTGTAATTAC >98431_98431_3_VPS41-CEP41_VPS41_chr7_38794302_ENST00000310301_CEP41_chr7_130067859_ENST00000489512_length(amino acids)=639AA_BP=596 MAEAEEQETGSLEESTDESEEEESEEEPKLKYERLSNGVTEILQKDAASCMTVHDKFLALGTHYGKVYLLDVQGNITQKFDVSPVKINQI SLDESGEHMGVCSEDGKVQVFGLYSGEEFHETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGEGNIRSVKWR GHLIAWANNMGVKIFDIISKQRITNVPRDDISLRPDMYPCSLCWKDNVTLIIGWGTSVKVCSVKERHASEMRDLPSRYVEIVSQFETEFY ISGLAPLCDQLVVLSYVKEISEKTEREYCARPRLDIIQPLSETCEEISSDALTVRGFQENECRDYHLEYSEGESLFYIVSPRDVVVAKER DQDDHIDWLLEKKKYEEALMAAEISQKNIKRHKILDIGLAYINHLVERGDYDIAARKCQKILGKNAALWEYEVYKFKEIGQLKAISPYLP RGDPVLKPLIYEMILHEFLESDYEGFATLIREWPGDLYNNSVIVQAVRDHLKKDSQNKTLLKTLAELYTYDKNYGNALEIYLTLRHKDVF QLIHKHNLFSSIKDKIVLLMDFDSEKAVDMLLDNEDKISIKKVVEELEDRPELQHVYLMKRIPQNPRYQHIKSRLDTGACVYLTSSPALP -------------------------------------------------------------- >98431_98431_4_VPS41-CEP41_VPS41_chr7_38794302_ENST00000310301_CEP41_chr7_130067859_ENST00000541543_length(transcript)=3028nt_BP=1843nt AAGTGTGTGGTTTCCTCTTATTTCCGGGTCTGTCAGGTGACTCTCCCGTGGCGCCATGGCGGAAGCAGAGGAGCAGGAAACTGGGTCCCT TGAAGAATCTACAGATGAGTCTGAGGAAGAAGAGAGCGAAGAGGAACCCAAGCTGAAGTATGAAAGGCTTTCCAATGGGGTAACTGAAAT ACTTCAGAAGGATGCAGCTAGCTGCATGACAGTCCATGACAAGTTTTTGGCATTGGGCACACATTATGGCAAGGTTTATTTACTTGATGT CCAGGGGAACATCACTCAGAAGTTTGATGTAAGTCCTGTGAAGATAAATCAGATTAGCTTGGATGAAAGTGGAGAGCACATGGGTGTGTG TTCAGAGGATGGCAAGGTGCAGGTATTTGGACTGTATTCTGGAGAAGAATTTCACGAGACTTTTGACTGTCCCATTAAAATTATTGCTGT GCACCCACATTTCGTGAGATCCAGTTGCAAGCAGTTTGTGACCGGAGGGAAGAAGCTGCTACTGTTTGAACGGTCTTGGATGAACAGATG GAAGTCTGCTGTTCTGCATGAAGGGGAAGGGAACATAAGGAGTGTGAAGTGGAGAGGCCATCTGATTGCTTGGGCCAATAATATGGGTGT GAAGATTTTTGACATCATCTCAAAGCAAAGAATCACCAATGTGCCCCGGGATGATATAAGTCTTCGCCCAGACATGTATCCCTGCAGCCT CTGCTGGAAGGACAATGTGACACTGATTATTGGCTGGGGGACTTCTGTCAAGGTGTGCTCAGTGAAGGAACGGCATGCCAGTGAAATGAG GGATTTGCCAAGTCGATATGTTGAAATAGTGTCTCAGTTTGAAACTGAATTCTACATCAGTGGACTTGCACCTCTCTGTGATCAGCTTGT TGTACTTTCGTATGTAAAGGAGATTTCAGAAAAAACGGAAAGAGAATACTGTGCCAGGCCTAGACTGGACATCATCCAGCCACTTTCTGA GACTTGTGAAGAGATCTCTTCTGATGCTTTGACAGTCAGAGGCTTTCAGGAGAATGAATGTAGAGATTATCATTTAGAATACTCTGAAGG GGAATCACTTTTTTACATCGTGAGTCCGAGAGATGTTGTAGTGGCCAAGGAACGAGACCAAGATGATCACATTGACTGGCTCCTTGAAAA GAAGAAATATGAAGAAGCATTGATGGCAGCTGAAATTAGCCAAAAAAATATTAAAAGACATAAGATTCTGGATATTGGCTTGGCATATAT AAATCACCTGGTGGAGAGAGGAGACTATGACATAGCAGCACGCAAATGCCAGAAAATTCTTGGGAAAAATGCAGCACTCTGGGAATATGA AGTTTATAAATTTAAAGAAATTGGACAGCTTAAGGCTATTAGTCCTTATTTGCCAAGAGGTGATCCAGTTCTGAAACCACTCATCTATGA AATGATCTTACATGAATTTTTGGAGAGTGATTATGAGGGTTTTGCCACATTGATCCGAGAATGGCCTGGAGATCTGTATAATAATTCAGT CATAGTTCAAGCAGTTCGGGATCATTTGAAGAAAGATAGTCAGAACAAGACTTTACTTAAAACCCTGGCAGAATTGTACACCTATGACAA GAACTATGGCAATGCTCTGGAAATATACTTAACATTAAGACATAAAGACGTTTTTCAGTTGATCCACAAGCATAATCTTTTCAGTTCTAT CAAGGATAAAATTGTTTTATTAATGGATTTTGATTCAGAGAAAGCTGTTGACATGCTTTTGGACAATGAAGATAAAATTTCAATTAAAAA GGTAGTGGAAGAATTGGAAGACAGACCAGAGCTACAGCATGTGTATCTGATGAAAAGGATACCACAGAACCCAAGATACCAGCATATCAA ATCAAGACTGGACACTGATTATAGATACAAAAAAGATGAGCTTTTCAAGAGACTAAAAGTTACAACTTTTGCCCAGCTGATCATCCAAGT TGCTTCCCTCTCTGATCAAACACTGGAAGTGACAGCTGAGGAGATTCAAAGGCTGGAAGACAATGATTCTGCAGCTTCAGACCCTGATGC TGAAACCACTGCCAGGACCAATGGGAAAGGAAATCCAGGTGAGCAGTCGCCGAGCCCTGAGCAGTTCATAAACAACGCAGGAGCAGGGGA CTCCAGCCGCTCAACTCTTCAGAGTGTCATCAGTGGTGTTGGGGAACTGGATCTAGACAAAGGGCCAGTGAAGAAAGCAGAGCCCCATAC CAAAGACAAACCTTATCCTGACTGCCCCTTCCTGCTGCTAGATGTGCGTGATAGAGATTCTTACCAGCAGTGCCACATTGTTGGAGCTTA CAGTTACCCAATTGCAACTCTGTCTAGAACAATGAACCCTTATTCAAATGATATTCTTGAATATAAAAATGCCCATGGCAAGATCATCAT TCTGTATGACGATGATGAAAGGCTGGCCAGTCAGGCGGCCACCACCATGTGCGAGCGTGGATTTGAAAACCTCTTCATGCTTTCCGGAGG CCGACTGAACCAAGCTAACTCCTCCGGAAGAGAGTCCAAGGTGCCTGGTGCCCGAAGCGCTCAGAATCTGCCAGGTGGCGGCCCCGCCAG CCACTCAAACCCCCGCTCCCTCAGCAGTGGTCACCTGCAAGGCAAACCCTGGAAGTAAAGACTTTGTCTCACTTAGGCAAATAAATGTTC TTCCTCTTTTCAGAACCCCTGAGCATTTCCCAAGTTGGGTCATTTCCAGAAACTTCTGCAGAGGAAAGACCATGACATATGTATGGGATA GGCCTCTTCCCTGTCCCTGTCTCCAGTTCCTCTCCCCTCAGGAGGCCACCTCAGGAAGGATTTTGACAGGTGACCATAAAAACCAGAGGT GTGACAGGCTCTAGTCTCCTCCCTGTTGTTTACAGCATATTTAAGTCTTGTGAAACTGTATAGGAAAAAAGTATCTACGTTTTTAGTTTT >98431_98431_4_VPS41-CEP41_VPS41_chr7_38794302_ENST00000310301_CEP41_chr7_130067859_ENST00000541543_length(amino acids)=870AA_BP=596 MAEAEEQETGSLEESTDESEEEESEEEPKLKYERLSNGVTEILQKDAASCMTVHDKFLALGTHYGKVYLLDVQGNITQKFDVSPVKINQI SLDESGEHMGVCSEDGKVQVFGLYSGEEFHETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGEGNIRSVKWR GHLIAWANNMGVKIFDIISKQRITNVPRDDISLRPDMYPCSLCWKDNVTLIIGWGTSVKVCSVKERHASEMRDLPSRYVEIVSQFETEFY ISGLAPLCDQLVVLSYVKEISEKTEREYCARPRLDIIQPLSETCEEISSDALTVRGFQENECRDYHLEYSEGESLFYIVSPRDVVVAKER DQDDHIDWLLEKKKYEEALMAAEISQKNIKRHKILDIGLAYINHLVERGDYDIAARKCQKILGKNAALWEYEVYKFKEIGQLKAISPYLP RGDPVLKPLIYEMILHEFLESDYEGFATLIREWPGDLYNNSVIVQAVRDHLKKDSQNKTLLKTLAELYTYDKNYGNALEIYLTLRHKDVF QLIHKHNLFSSIKDKIVLLMDFDSEKAVDMLLDNEDKISIKKVVEELEDRPELQHVYLMKRIPQNPRYQHIKSRLDTDYRYKKDELFKRL KVTTFAQLIIQVASLSDQTLEVTAEEIQRLEDNDSAASDPDAETTARTNGKGNPGEQSPSPEQFINNAGAGDSSRSTLQSVISGVGELDL DKGPVKKAEPHTKDKPYPDCPFLLLDVRDRDSYQQCHIVGAYSYPIATLSRTMNPYSNDILEYKNAHGKIIILYDDDERLASQAATTMCE -------------------------------------------------------------- >98431_98431_5_VPS41-CEP41_VPS41_chr7_38794302_ENST00000395969_CEP41_chr7_130067859_ENST00000223208_length(transcript)=7922nt_BP=1713nt ATGGCGGAAGCAGAGGAGCAGGAAACTGGGTCCCTTGAAGAATCTACAGATGAGTCTGAGGAAGAAGAGAGCGAAGAGGAACCCAAGCTG AAGTATGAAAGGCTTTCCAATGGGGTAACTGAAATACTTCAGAAGGATGCAGCTAGCTGCATGACAGTCCATGACAAGTTTTTGGCATTG GGCACACATTATGGCAAGGTTTATTTACTTGATGTCCAGGGGAACATCACTCAGAAGTTTGATGTAGTGCAGGTATTTGGACTGTATTCT GGAGAAGAATTTCACGAGACTTTTGACTGTCCCATTAAAATTATTGCTGTGCACCCACATTTCGTGAGATCCAGTTGCAAGCAGTTTGTG ACCGGAGGGAAGAAGCTGCTACTGTTTGAACGGTCTTGGATGAACAGATGGAAGTCTGCTGTTCTGCATGAAGGGGAAGGGAACATAAGG AGTGTGAAGTGGAGAGGCCATCTGATTGCTTGGGCCAATAATATGGGTGTGAAGATTTTTGACATCATCTCAAAGCAAAGAATCACCAAT GTGCCCCGGGATGATATAAGTCTTCGCCCAGACATGTATCCCTGCAGCCTCTGCTGGAAGGACAATGTGACACTGATTATTGGCTGGGGG ACTTCTGTCAAGGTGTGCTCAGTGAAGGAACGGCATGCCAGTGAAATGAGGGATTTGCCAAGTCGATATGTTGAAATAGTGTCTCAGTTT GAAACTGAATTCTACATCAGTGGACTTGCACCTCTCTGTGATCAGCTTGTTGTACTTTCGTATGTAAAGGAGATTTCAGAAAAAACGGAA AGAGAATACTGTGCCAGGCCTAGACTGGACATCATCCAGCCACTTTCTGAGACTTGTGAAGAGATCTCTTCTGATGCTTTGACAGTCAGA GGCTTTCAGGAGAATGAATGTAGAGATTATCATTTAGAATACTCTGAAGGGGAATCACTTTTTTACATCGTGAGTCCGAGAGATGTTGTA GTGGCCAAGGAACGAGACCAAGATGATCACATTGACTGGCTCCTTGAAAAGAAGAAATATGAAGAAGCATTGATGGCAGCTGAAATTAGC CAAAAAAATATTAAAAGACATAAGATTCTGGATATTGGCTTGGCATATATAAATCACCTGGTGGAGAGAGGAGACTATGACATAGCAGCA CGCAAATGCCAGAAAATTCTTGGGAAAAATGCAGCACTCTGGGAATATGAAGTTTATAAATTTAAAGAAATTGGACAGCTTAAGGCTATT AGTCCTTATTTGCCAAGAGGTGATCCAGTTCTGAAACCACTCATCTATGAAATGATCTTACATGAATTTTTGGAGAGTGATTATGAGGGT TTTGCCACATTGATCCGAGAATGGCCTGGAGATCTGTATAATAATTCAGTCATAGTTCAAGCAGTTCGGGATCATTTGAAGAAAGATAGT CAGAACAAGACTTTACTTAAAACCCTGGCAGAATTGTACACCTATGACAAGAACTATGGCAATGCTCTGGAAATATACTTAACATTAAGA CATAAAGACGTTTTTCAGTTGATCCACAAGCATAATCTTTTCAGTTCTATCAAGGATAAAATTGTTTTATTAATGGATTTTGATTCAGAG AAAGCTGTTGACATGCTTTTGGACAATGAAGATAAAATTTCAATTAAAAAGGTAGTGGAAGAATTGGAAGACAGACCAGAGCTACAGCAT GTGTATCTGATGAAAAGGATACCACAGAACCCAAGATACCAGCATATCAAATCAAGACTGGACACTGGTAACAGTATGACTAAATATACT GAGAAGCTCGAAGAGATTAAGAAAAATTATAGATACAAAAAAGATGAGCTTTTCAAGAGACTAAAAGTTACAACTTTTGCCCAGCTGATC ATCCAAGTTGCTTCCCTCTCTGATCAAACACTGGAAGTGACAGCTGAGGAGATTCAAAGGCTGGAAGACAATGATTCTGCAGCTTCAGAC CCTGATGCTGAAACCACTGCCAGGACCAATGGGAAAGGAAATCCAGGTGAGCAGTCGCCGAGCCCTGAGCAGTTCATAAACAACGCAGGA GCAGGGGACTCCAGCCGCTCAACTCTTCAGAGTGTCATCAGTGGTGTTGGGGAACTGGATCTAGACAAAGGGCCAGTGAAGAAAGCAGAG CCCCATACCAAAGACAAACCTTATCCTGACTGCCCCTTCCTGCTGCTAGATGTGCGTGATAGAGATTCTTACCAGCAGTGCCACATTGTT GGAGCTTACAGTTACCCAATTGCAACTCTGTCTAGAACAATGAACCCTTATTCAAATGATATTCTTGAATATAAAAATGCCCATGGCAAG ATCATCATTCTGTATGACGATGATGAAAGGCTGGCCAGTCAGGCGGCCACCACCATGTGCGAGCGTGGATTTGAAAACCTCTTCATGCTT TCCGGAGGTCTAAAAGTCTTAGCTCAGAAATTCCCGGAAGGACTGATTACTGGTTCCCTGCCAGCATCTTGCCAGCAGGCCCTTCCTCCT GGGTCTGCCCGGAAACGATCCAGCCCCAAAGGGCCACCCCTACCAGCTGAGAATAAATGGAGATTTACCCCAGAAGACTTAAAAAAGATA GAATATTATCTGGAAGAGGAGCAAGGGCCTGCAGATCATCCTAGCCGACTGAACCAAGCTAACTCCTCCGGAAGAGAGTCCAAGGTGCCT GGTGCCCGAAGCGCTCAGAATCTGCCAGGTGGCGGCCCCGCCAGCCACTCAAACCCCCGCTCCCTCAGCAGTGGTCACCTGCAAGGCAAA CCCTGGAAGTAAAGACTTTGTCTCACTTAGGCAAATAAATGTTCTTCCTCTTTTCAGAACCCCTGAGCATTTCCCAAGTTGGGTCATTTC CAGAAACTTCTGCAGAGGAAAGACCATGACATATGTATGGGATAGGCCTCTTCCCTGTCCCTGTCTCCAGTTCCTCTCCCCTCAGGAGGC CACCTCAGGAAGGATTTTGACAGGTGACCATAAAAACCAGAGGTGTGACAGGCTCTAGTCTCCTCCCTGTTGTTTACAGCATATTTAAGT CTTGTGAAACTGTATAGGAAAAAAGTATCTACGTTTTTAGTTTTTTTGTTTTGTTTTTTTTTAATAAGGTCCAGCTTGTTGGGTCTCTCT GTGTTGTTTTGTAAATACTTCAGTCACATCTGCCCGTGTGCCTGTCCCTGCCACCTTTTCATTCACTGTTCTTGACTTCATGAAGGCTTC TCCGGGCAGTCTTGGTGTGAGAAGCTGTTTCCAAGGGTGCAGATGAGCCTTAGGTTCCAGCCGCCTGCAGACCCCACCCCAGCAGGCTCA CTCAGCAAGGAGCTCTCTGCCCAGCATATTGCAGGCCCTGTTTTGAGTATGGAAGCCAGTGCCTGTGTACTCACTGAAATTGAAGATGAG GAAAGTAGCTGTACACTCACTGAATGCTCCCCCTTACTAGATATTTCCTGGAGCCAGAAAGGTATGCATGTGGGTGTCTTCACACCGGGG AGGAGGGCCTCTCATGGGAAAGCCCTGGCCACCACACCGGCCTGTGCCCCTTGAAGCCCACCAAAGCGGCCCTCACTTGTGGTCAGTATA TCAGTTATGACGCCCATTGCCCAGCTTCAGTCCATCCATGTTAGATGGACAGAAATTATGGCCAGTTGAAAATACCAGCTTTGGTTGGAC AACTGTGGACACACAAGGTGAAGAGGACTCCGAAGTCCTTTGTCAGGGCTGACAACCTCGTAAGCCCTTGCTTAGAAATACAGTATTAGT CTAATTGAGTAATTAGTGCAATTTCCTGCTTACTTTTCATTCTCATGACTGAACTGTGATTAGGAAGTTGTGATTATAGATTCTGGTTTT GGCCGGAATTTTGAATCAGCATTAATTGAATTGCTAAATGACTGACATTCATTCCATTTAATTGGGGGAACAAAAGGCCTCAGGTAAGGA TGAGGAACTCTGAAATCAGATGGAAAAGAGCGGTGTTAATTTTTATGGTCTGTGATCGTAGCTGTGATAAGGGACTGAGGAATAAATTGT GCTCTTTGTCATGGCAACCAGCTTCTGAAAAGCCCACTGAAAATTGCCTGTCCTGCTGGTAACTGCTACGGGGTAAGATTTGCCTTAACA GTACTATTTTCTCGCCACCAAAAAAAAAAAAAAAAAAAAAAAAAAATGCACCACAGTATTTCTAGCATGGGGGCTGTGTTTGTATGAGAA ATAAACGTAATAAATATCTCATAGAGACATATGGAAAAATAACTTTCAGATTCAGCCCAGTTCTGTTTTAGAGTGTGTTTATTCTTCTCT ACTTGATTTCCAAAGTGCAACATTTTCCGATGCTTTAGAAATCAAACAAACCAGGGACATTGTTCAGATGTCAAGCCATGCCCAATTTTC CACAAGATTCAAGAATCTTGTATAAAATTCAGCCAACGTACACATAGCTTTAATGAGGAGCCTGTCATGTTTCCCCATAAATTTATTGCC TGAGAACTTAGTTCAGCCTTTGCTAATGCCAAAATGCTCTGGCTTTGTATTTTCTTTACAGCATAGATAGAAAAATGCACATTTTTCCAC ACTCAGCTTTCCCCTAGCATGGACAAGATTTTCAGCCATTTTTGCCACATATACATTTTTAAGGAAAAAAGATTTTTCTCTGTAAGAAAG TTCTGGTTATGCTGTTTTAAAGGTGACTTGTCAGGAGTTGAGACTTCCCTGCCGGATTCTATTTTGAAAGTAAATGGTCTTCCCTCCTTG TTCCGATTCTGCGTTCCCATCGTCAGACAACTTTGGAGTATTAGAAACCACTGTATATATGTGGAAAGCCAGGTCAGCCAGACCTGTTAG AATTGGTGTGCACTCACCTGAGAGATCTGGCAGGTTGGATATATTTATGTGTATTTCTCCACAGTGCTTGCTTTGCCCTGTTGGTAAGGA TTTTAAATAACCATGCTCAAAAGAGCTGTTCTAATCTGCGTTTTGCATGTTAAGTGTTAATATCAAACATTCTTTACGTGCTCGAGGTAT TGCTTTTAACATTCTACTTTGCCAGTTTCTTCATTAGATTAATTGACATGTATTATTTAAATGACCAGTGATGCTTTGTGCAATTATGAA TGTTGAAGATTAAAGTACATAGTTACTAATTTGTCGTTTGCTATTAATATGCTGAAAACTGCCAACTTCTCTCTTCTTTTCTGTCGAGAT GATTTGGGGGAGCCACAGGAGACTGGTGTGATTTTTGCTGCATCTCCTAGGAAAGCATTTTTTAAAAAAAATAAATGAATCAGGAAATCA GTCCAATTAGGGCAGGGGGCCTCAGCTCTCCAGTCAGAAAGCCTGGATTTCTTTTCCTGCTCAGGCTGGGACTGAAGCCACCTTCAACAA CTGGATCATGGCTTCCTACCAGCGTCTCAGGGGTTGACTAGCTGCCCTTGTCTGGGGCTTGTGAACCCTGAGACAGAAGGTGCTTCATCG ATGTACAACTACAGCACCCTGAACAGCAGTGATGGCCAAAGTTTAAATAATACCTTAAATGCTTTAAAGGGGTTTGTGTTTAAGGAAGGG AGAAAAGAAAAAAAGAAAGGAAGGGAGAAAGAAGCAAGGAAATGGGAAGAAGGGAGGGCAGAGAGAAGAAAAGAAGCAGAAAGCGAGAGA GAAAGGAGAAAGCTACATTACTTATTTGAAAACAAAAGGAACACCCTGGGCTGTAATAATGTCAGGCTCAATCTCTTGAAAAAGTATGGA ATGATTTAAATGGCCTGCATTCATTTTATCTTTTATCTTTTTTTTTTTTTTTAACCTTTAGTGGTTAGCCAGGACCAGCACGATCATATT GGGCTTGGTATAAATCCGAATGAAAAGAGACCAAATAACATTCATTAGTTGCTCAGGGATTTTTCCTGTGGTGCTATTTAAATTATACAA AAATTCTTAAGACTTTAGGCTACTCGACCAAGAAAACAGAACAAAACAAAAAATCGTGTTTTCTCTAATTCCCTTGTGGAATGTAAGTGA AATCAGAGTCCTAGGCTAGGAAGAAATACGTAGGTAATTTTTCTTGTGTTGGTTTTGGTTTCTGTCATGTTGTTTATTGGCTATAGATTC TGTCTTTTATGTTATCTGACTTTTTTAGAGCGAATAATTAGTTTCTGTCCACCTGGATTTAAATCCATGACCACCTTCTTGCTCTACTCT GAAGATAATCAGTAAGAACCTTTCTTTCTCCAGTTCTAAAACGTTCTCAGTGTCTTTAATGTGTGTTTATTTTCTTCCCAATTCTTTCAA AGATTTAACTCCCACGATACTTTTTTTTCCCCAGGAAACACCGCAAATGTGTGGAATATAATTCACCAGTTTAATTATGTGAGCATGTTG AGTACTTACATGCAGGTCCATTAATTTTTCACTAACAATTATTTTTTCATGCAAAAGCAATAAATAACATTGTGCTTCCAAAATGTTCAG AATACATTTGGGTAGTAATACTTTCCTAGATTTACAATAATTATTGAAATTATTATTATGACATCTTTAAATGGATACACAGGTCAGTTA CAACATAAAAAATGTAATGGTGGAAATTTGTCAGCCTTGAATTCAGGCAGAACAGGATTCGGTGCATGATTTTATGTGTTTTCGAAACGG TGTCTGTCACATTGTGATCCCCTGATGGCTCCCCTCTCTGTTGCTGATCCTCTTTGTTCTGTACAGAAGCAAATTCTCACCTGTGTAACA TCCTGAAGCACCTGGTAAAATGTGAGGCAAAGAGAGGCCACTTCTCAAATGCTGTGGACGGATGGGCTGCATCTTTTAAAGGATATCAAT ATGTCTTCCTGTTGCAATTATTTTGACTATAAGCTCCCAGAGAGTGAAAATCACCAACCCTGTGACAGTGGCCCTTAATAAGTGTTCATG AATAAATGAATTGAACCTGTCAAGATTGAAGTTTGGATGTGATGCCCACTGTGGTGGCCACTCAGTGCTAGTCTGTCATTCTGGAGACCC AGAAAGCTCGTTATCTTCTGTCCCCCTTGTGTATCCTGCCTTTGTGGGCGAGGCATTCAAAACCCTGAGGTTTTTAGATCTCCCTCTACA GGAAGTACCCAGAGAGCTGCTGGGGGTGTTATTACCCTGTCTCTGCCAGGCTTAAAGTATCCTCCCAAATTCAGCACGCAAAGGTCACAC ACCACCCCCATCTTAAGAGTAGGTTTTCTCTTTTGTTTCAAATCTTGAAGATTTCCAGAAAATAATAATACTAGCCAATGTTTGTGGAGA GCTTACTTTGCTCCTAGATTCTTCATTATATGTTTTGACCCATTTAATTTCCACAACAGTCTGATGAGGCAGGCACCCCCATTTTCAGAT GAGGAGACTGAGGTTCGGGTAGAAATTAAGTGACTCAGGTTTGCCTTCAGTCTCTGACCAAGGGTTTGAAAAGCCAGGAGCCAGCCTGAG AACTGTGGCTCCAGAGGGTGTTCTTTCAGCCACTCCGCTCTATGCTTCTCACTCTGGGTGGGCACAACCATGTTCTCCTTTGGTGATGCC TCTAACTTACCGTGAAAATGTACCTTTCCCTTCGCTATTGGCTTCCCTTCCCTCCTAGTCAGCCGAGATTCTTTTGAAAACTTTCCTCCG CTTGCCTGCACAAAAGGCGATGGAAATTCAGGAACTGAAACATCTGCTCTGGGGAATGCGTATTTCCACATTTCCACCGCCTGTGTCTGC TGTCTTATCTTGAAGACAGGTGCTCCAGGGCTTCCGAGGTTATTTTGTCTGTTAATGGACACCTTGCAAAGTACCACTTAAGGAATGAGA ATTACAAACTTTTAATTATATTGTAGGGGGAAAAAAGTAGGCTGTTTTCCTGATAGGTCTAGCCATTCATTCAGTAAACCATATTGATAT >98431_98431_5_VPS41-CEP41_VPS41_chr7_38794302_ENST00000395969_CEP41_chr7_130067859_ENST00000223208_length(amino acids)=933AA_BP=571 MAEAEEQETGSLEESTDESEEEESEEEPKLKYERLSNGVTEILQKDAASCMTVHDKFLALGTHYGKVYLLDVQGNITQKFDVVQVFGLYS GEEFHETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGEGNIRSVKWRGHLIAWANNMGVKIFDIISKQRITN VPRDDISLRPDMYPCSLCWKDNVTLIIGWGTSVKVCSVKERHASEMRDLPSRYVEIVSQFETEFYISGLAPLCDQLVVLSYVKEISEKTE REYCARPRLDIIQPLSETCEEISSDALTVRGFQENECRDYHLEYSEGESLFYIVSPRDVVVAKERDQDDHIDWLLEKKKYEEALMAAEIS QKNIKRHKILDIGLAYINHLVERGDYDIAARKCQKILGKNAALWEYEVYKFKEIGQLKAISPYLPRGDPVLKPLIYEMILHEFLESDYEG FATLIREWPGDLYNNSVIVQAVRDHLKKDSQNKTLLKTLAELYTYDKNYGNALEIYLTLRHKDVFQLIHKHNLFSSIKDKIVLLMDFDSE KAVDMLLDNEDKISIKKVVEELEDRPELQHVYLMKRIPQNPRYQHIKSRLDTGNSMTKYTEKLEEIKKNYRYKKDELFKRLKVTTFAQLI IQVASLSDQTLEVTAEEIQRLEDNDSAASDPDAETTARTNGKGNPGEQSPSPEQFINNAGAGDSSRSTLQSVISGVGELDLDKGPVKKAE PHTKDKPYPDCPFLLLDVRDRDSYQQCHIVGAYSYPIATLSRTMNPYSNDILEYKNAHGKIIILYDDDERLASQAATTMCERGFENLFML SGGLKVLAQKFPEGLITGSLPASCQQALPPGSARKRSSPKGPPLPAENKWRFTPEDLKKIEYYLEEEQGPADHPSRLNQANSSGRESKVP -------------------------------------------------------------- >98431_98431_6_VPS41-CEP41_VPS41_chr7_38794302_ENST00000395969_CEP41_chr7_130067859_ENST00000343969_length(transcript)=2738nt_BP=1713nt ATGGCGGAAGCAGAGGAGCAGGAAACTGGGTCCCTTGAAGAATCTACAGATGAGTCTGAGGAAGAAGAGAGCGAAGAGGAACCCAAGCTG AAGTATGAAAGGCTTTCCAATGGGGTAACTGAAATACTTCAGAAGGATGCAGCTAGCTGCATGACAGTCCATGACAAGTTTTTGGCATTG GGCACACATTATGGCAAGGTTTATTTACTTGATGTCCAGGGGAACATCACTCAGAAGTTTGATGTAGTGCAGGTATTTGGACTGTATTCT GGAGAAGAATTTCACGAGACTTTTGACTGTCCCATTAAAATTATTGCTGTGCACCCACATTTCGTGAGATCCAGTTGCAAGCAGTTTGTG ACCGGAGGGAAGAAGCTGCTACTGTTTGAACGGTCTTGGATGAACAGATGGAAGTCTGCTGTTCTGCATGAAGGGGAAGGGAACATAAGG AGTGTGAAGTGGAGAGGCCATCTGATTGCTTGGGCCAATAATATGGGTGTGAAGATTTTTGACATCATCTCAAAGCAAAGAATCACCAAT GTGCCCCGGGATGATATAAGTCTTCGCCCAGACATGTATCCCTGCAGCCTCTGCTGGAAGGACAATGTGACACTGATTATTGGCTGGGGG ACTTCTGTCAAGGTGTGCTCAGTGAAGGAACGGCATGCCAGTGAAATGAGGGATTTGCCAAGTCGATATGTTGAAATAGTGTCTCAGTTT GAAACTGAATTCTACATCAGTGGACTTGCACCTCTCTGTGATCAGCTTGTTGTACTTTCGTATGTAAAGGAGATTTCAGAAAAAACGGAA AGAGAATACTGTGCCAGGCCTAGACTGGACATCATCCAGCCACTTTCTGAGACTTGTGAAGAGATCTCTTCTGATGCTTTGACAGTCAGA GGCTTTCAGGAGAATGAATGTAGAGATTATCATTTAGAATACTCTGAAGGGGAATCACTTTTTTACATCGTGAGTCCGAGAGATGTTGTA GTGGCCAAGGAACGAGACCAAGATGATCACATTGACTGGCTCCTTGAAAAGAAGAAATATGAAGAAGCATTGATGGCAGCTGAAATTAGC CAAAAAAATATTAAAAGACATAAGATTCTGGATATTGGCTTGGCATATATAAATCACCTGGTGGAGAGAGGAGACTATGACATAGCAGCA CGCAAATGCCAGAAAATTCTTGGGAAAAATGCAGCACTCTGGGAATATGAAGTTTATAAATTTAAAGAAATTGGACAGCTTAAGGCTATT AGTCCTTATTTGCCAAGAGGTGATCCAGTTCTGAAACCACTCATCTATGAAATGATCTTACATGAATTTTTGGAGAGTGATTATGAGGGT TTTGCCACATTGATCCGAGAATGGCCTGGAGATCTGTATAATAATTCAGTCATAGTTCAAGCAGTTCGGGATCATTTGAAGAAAGATAGT CAGAACAAGACTTTACTTAAAACCCTGGCAGAATTGTACACCTATGACAAGAACTATGGCAATGCTCTGGAAATATACTTAACATTAAGA CATAAAGACGTTTTTCAGTTGATCCACAAGCATAATCTTTTCAGTTCTATCAAGGATAAAATTGTTTTATTAATGGATTTTGATTCAGAG AAAGCTGTTGACATGCTTTTGGACAATGAAGATAAAATTTCAATTAAAAAGGTAGTGGAAGAATTGGAAGACAGACCAGAGCTACAGCAT GTGTATCTGATGAAAAGGATACCACAGAACCCAAGATACCAGCATATCAAATCAAGACTGGACACTGGTAACAGTATGACTAAATATACT GAGAAGCTCGAAGAGATTAAGAAAAATTATAGATACAAAAAAGATGAGCTTTTCAAGAGACTAAAAGTTACAACTTTTGCCCAGCTGATC ATCCAAGTTGCTTCCCTCTCTGATCAAACACTGGAAGTGACAGCTGAGGAGATTCAAAGGCTGGAAGACAATGATTCTGCAGCTTCAGAC CCTGATGCTGAAACCACTGCCAGGACCAATGGGAAAGGAAATCCAGGTGAGCAGTCGCCGAGCCCTGAGCAGTTCATAAACAACGCAGGA GCAGGGGACTCCAGCCGCTCAACTCTTCAGAGTGTCATCAGTGGTGTTGGGGAACTGGATCTAGACAAAGGGCCAGTGAAGAAAGCAGAG CCCCATACCAAAGACAAACCTTATCCTGACTGCCCCTTCCTGCTGCTAGATGTGCGTGATAGAGATTCTTACCAGCAGTGCCACATTGTT GGAGCTTACAGTTACCCAATTGCAACTCTGTCTAGAACAATGAACCCTTATTCAAATGATATTCTTGAATATAAAAATGCCCATGGCAAG ATCATCATTCTGTATGACGATGATGAAAGGCTGGCCAGTCAGGCGGCCACCACCATGTGCGAGCGTGGATTTGAAAACCTCTTCATGCTT TCCGGAGGCCGACTGAACCAAGCTAACTCCTCCGGAAGAGAGTCCAAGGTGCCTGGTGCCCGAAGCGCTCAGAATCTGCCAGGTGGCGGC CCCGCCAGCCACTCAAACCCCCGCTCCCTCAGCAGTGGTCACCTGCAAGGCAAACCCTGGAAGTAAAGACTTTGTCTCACTTAGGCAAAT AAATGTTCTTCCTCTTTTCAGAACCCCTGAGCATTTCCCAAGTTGGGTCATTTCCAGAAACTTCTGCAGAGGAAAGACCATGACATATGT >98431_98431_6_VPS41-CEP41_VPS41_chr7_38794302_ENST00000395969_CEP41_chr7_130067859_ENST00000343969_length(amino acids)=861AA_BP=571 MAEAEEQETGSLEESTDESEEEESEEEPKLKYERLSNGVTEILQKDAASCMTVHDKFLALGTHYGKVYLLDVQGNITQKFDVVQVFGLYS GEEFHETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGEGNIRSVKWRGHLIAWANNMGVKIFDIISKQRITN VPRDDISLRPDMYPCSLCWKDNVTLIIGWGTSVKVCSVKERHASEMRDLPSRYVEIVSQFETEFYISGLAPLCDQLVVLSYVKEISEKTE REYCARPRLDIIQPLSETCEEISSDALTVRGFQENECRDYHLEYSEGESLFYIVSPRDVVVAKERDQDDHIDWLLEKKKYEEALMAAEIS QKNIKRHKILDIGLAYINHLVERGDYDIAARKCQKILGKNAALWEYEVYKFKEIGQLKAISPYLPRGDPVLKPLIYEMILHEFLESDYEG FATLIREWPGDLYNNSVIVQAVRDHLKKDSQNKTLLKTLAELYTYDKNYGNALEIYLTLRHKDVFQLIHKHNLFSSIKDKIVLLMDFDSE KAVDMLLDNEDKISIKKVVEELEDRPELQHVYLMKRIPQNPRYQHIKSRLDTGNSMTKYTEKLEEIKKNYRYKKDELFKRLKVTTFAQLI IQVASLSDQTLEVTAEEIQRLEDNDSAASDPDAETTARTNGKGNPGEQSPSPEQFINNAGAGDSSRSTLQSVISGVGELDLDKGPVKKAE PHTKDKPYPDCPFLLLDVRDRDSYQQCHIVGAYSYPIATLSRTMNPYSNDILEYKNAHGKIIILYDDDERLASQAATTMCERGFENLFML -------------------------------------------------------------- >98431_98431_7_VPS41-CEP41_VPS41_chr7_38794302_ENST00000395969_CEP41_chr7_130067859_ENST00000489512_length(transcript)=4751nt_BP=1713nt ATGGCGGAAGCAGAGGAGCAGGAAACTGGGTCCCTTGAAGAATCTACAGATGAGTCTGAGGAAGAAGAGAGCGAAGAGGAACCCAAGCTG AAGTATGAAAGGCTTTCCAATGGGGTAACTGAAATACTTCAGAAGGATGCAGCTAGCTGCATGACAGTCCATGACAAGTTTTTGGCATTG GGCACACATTATGGCAAGGTTTATTTACTTGATGTCCAGGGGAACATCACTCAGAAGTTTGATGTAGTGCAGGTATTTGGACTGTATTCT GGAGAAGAATTTCACGAGACTTTTGACTGTCCCATTAAAATTATTGCTGTGCACCCACATTTCGTGAGATCCAGTTGCAAGCAGTTTGTG ACCGGAGGGAAGAAGCTGCTACTGTTTGAACGGTCTTGGATGAACAGATGGAAGTCTGCTGTTCTGCATGAAGGGGAAGGGAACATAAGG AGTGTGAAGTGGAGAGGCCATCTGATTGCTTGGGCCAATAATATGGGTGTGAAGATTTTTGACATCATCTCAAAGCAAAGAATCACCAAT GTGCCCCGGGATGATATAAGTCTTCGCCCAGACATGTATCCCTGCAGCCTCTGCTGGAAGGACAATGTGACACTGATTATTGGCTGGGGG ACTTCTGTCAAGGTGTGCTCAGTGAAGGAACGGCATGCCAGTGAAATGAGGGATTTGCCAAGTCGATATGTTGAAATAGTGTCTCAGTTT GAAACTGAATTCTACATCAGTGGACTTGCACCTCTCTGTGATCAGCTTGTTGTACTTTCGTATGTAAAGGAGATTTCAGAAAAAACGGAA AGAGAATACTGTGCCAGGCCTAGACTGGACATCATCCAGCCACTTTCTGAGACTTGTGAAGAGATCTCTTCTGATGCTTTGACAGTCAGA GGCTTTCAGGAGAATGAATGTAGAGATTATCATTTAGAATACTCTGAAGGGGAATCACTTTTTTACATCGTGAGTCCGAGAGATGTTGTA GTGGCCAAGGAACGAGACCAAGATGATCACATTGACTGGCTCCTTGAAAAGAAGAAATATGAAGAAGCATTGATGGCAGCTGAAATTAGC CAAAAAAATATTAAAAGACATAAGATTCTGGATATTGGCTTGGCATATATAAATCACCTGGTGGAGAGAGGAGACTATGACATAGCAGCA CGCAAATGCCAGAAAATTCTTGGGAAAAATGCAGCACTCTGGGAATATGAAGTTTATAAATTTAAAGAAATTGGACAGCTTAAGGCTATT AGTCCTTATTTGCCAAGAGGTGATCCAGTTCTGAAACCACTCATCTATGAAATGATCTTACATGAATTTTTGGAGAGTGATTATGAGGGT TTTGCCACATTGATCCGAGAATGGCCTGGAGATCTGTATAATAATTCAGTCATAGTTCAAGCAGTTCGGGATCATTTGAAGAAAGATAGT CAGAACAAGACTTTACTTAAAACCCTGGCAGAATTGTACACCTATGACAAGAACTATGGCAATGCTCTGGAAATATACTTAACATTAAGA CATAAAGACGTTTTTCAGTTGATCCACAAGCATAATCTTTTCAGTTCTATCAAGGATAAAATTGTTTTATTAATGGATTTTGATTCAGAG AAAGCTGTTGACATGCTTTTGGACAATGAAGATAAAATTTCAATTAAAAAGGTAGTGGAAGAATTGGAAGACAGACCAGAGCTACAGCAT GTGTATCTGATGAAAAGGATACCACAGAACCCAAGATACCAGCATATCAAATCAAGACTGGACACTGGTGCCTGTGTGTATCTTACCAGC TCCCCAGCACTGCCAGACTGTGCCATGAATGGATTATGCTTCTGATGAAATCCCTGGCTGCGTTTTGTTCAGTCACCACCGCAGGGTTCT TGTATATTCTCAAGCACCCTCTCTGGGTTTCTGTTTTGCAGCACTGCAGGCTGATTAAGGGACACTTTCCAAACCACAGGGCTCTCCCTT TATTAGTCCCCACAGTCTTTCATTGGCTGCATTGTCCTCCCATTTCTATCTATATTCAATCTAATTTCCAATTTCTTTAGCTTTCTGAAA TTCTGTAGGCTTTCTCCACTCAGTCTTTTCTAGCCTTATTTTTGTCTTTTTAAAAATTCACCTTCCTTTTATTATCTCTAGACAAACTAT TCATTCCCTCTTTTCTTCTTTAGGCTTTACTTTTCCTGAATATTTGCTAATAGCCTTGACTGTAAGCATCAAACTCATTATAGACTAGGT ACTCTTCATTTTTATTTGTTGTTTAATTCTGTTTCTTCCGTCAAAGGAAGAAATATATGTGAAAGGCTTTTATAAACCAGAAAGCACTAT ACACACATATCACTTATTGAGGTTAACAAAGGACCACTGTGCCTCTTTTCATGCTTTCTGCTCTTCCAAGCCAAGAGAACTTCTCCATAG AGGAGGGAAATATTGAAGAAAAATAAAGCCATGGAGTTGTCTCTTAGCAACTGAGTTCGTGCCTTATAAATCTCATCTACTTTAGATTAC TGCTGCACAAAATCACTTGCTTTTCTTATTGGCTCAGTATAAATAATGTTATTAAATTATAGGAAAACAATGGAAAAAATCTAATGAATG ACTCATTCACTGAATCAGTTGCACTCTGTGTTTGCACAGCACTGTTGCTATAGTCGGGTTGTTTCTTCCTCTTGATTCTAATTGTAAAGT TTTGTTATATATCTTTTATCACAACTTTAGTTGTAAGTAAACAAAGTAGAAGCTAAATGCTACCTTATACATTTATAGGTTGCTTAAGTC GTGAAGCAATATGAGTCATATATGTAGCACATAACATATACTGTATATAAGTCAAGTTGTACATAGTTTAAAGAAAATCAGGTGTGCAGA AACTCAGACCAAATTGGGAAGTATTTGCATTATAAAATAACTCATTATAAGGATTTTTCAGTTAGTAGATCTCCATAGTAAATTTCATTC AGCAAATGTGTATTTTTCCTATTTATTTATTTATTTATTTATTGAGATGAAGTCTCGCTCTGTTGCCCAAGCTGGAGTGCAGTGGCGTGA TCTTGGCTCACTGCAACCTCTGCCTCCCAGGTTCAAGCGATTCTTCTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGGTGCGCACCACC ATGCCTGGCTAATTTTTATATTTTTAGTAGAGACGGGGTTTTACTATGTTGGTCAGGCTGGTCTCGAACTCCTGACCTTGTGATCCTCCC GCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACTGTGCCAGGTCTAGTTATTTATTTATTTATTGTAGAGATGGGCTCTCA CTGTGTTGGCCAGGGTGGTCTTGAACTCCTGGCCTCGAGCAATCCTTCCACCTCAGTCTCCCAAAGTGCTGGGATTACAGGTGTGAGCTA TCACACCTGGCCATTTTTTTTTTTTTTTTTTTTTTTGAGATAGAGTCTCACTCTGTCACCCGCATTGTAGTGCAGTGGCGCATTCTTGCT CACTGCAACCTCCCCTTCCTGGGCTCAGGGGATCCTCCTACCTCAGCCTCTCAAGTAGCTGGGACTACAGGGATGTGCCACCATGCCTGG CTAGTTTTTGTGTATGTGTGTGTTTTGTAGAGACGAGGTCTCACTATTTTGCCCAGGCTGGTCCGGAACTCCTGGGCTCAAGCAATCCTG CCTCCTCAGCCTCCCAACGTGCTGGGATTGCAGGCATGATCCAGTGCACCTGACCATCATTCAGCAAGTATTTTTGAGTGTCTCCTATGC TAGACAATGGAAGGGATAAAGATTATTCATACGTGTGTGTGTGTGTGTGTGTGTACGTGCCCATAAATAGTCCTTGGCTTTCTGTCTAGT AAGGTAGGTAAGACAATACAGTGATAAATGCCTTGTGAGTTGTAAGCCGAGTGCTATAGAGGCTCAGAGGAGGGAAAGGTCACTTCCTGC TGAGTGAGCTCTTACGAGTATGTGGCAAGGTGATACGTTAGAGAATGCAAGACTAAGAGTTTGTCAAGTTAAGTAATTAAGGCAACATTA AGAGGTAGTGAGTTGGTGTCCAGTGCTAGAGCAAGGAGTTTCAGCTTTAGTTAGGAAGCAATGGGGAGCCACTGACTTTTTTTTTTCTTT TTGATCAAAAAGTCTTATCTGGGAAAATGTATCTGGCAGTAATGTGTAATTTCAATTTTTTTTAAAAAAAATTGGTTCTTGGATAGTCTT TTAGGCTTCTTTTGTATGAAACAAAGCCATGTTTATAAATAAGTGAATTATGAAATGGATTCATTTCCAATCTTTTTAAAAGGTAGTCAG AAACTATCTTCAGATGCAATTAGATACAGTAAGATAGGCTGCATAGTTAAGATGTAAGCAGTTTACACAGTGGGATAAAAATGCTACTTT TCATACTTTCTCAAACCATTTTTAGGGGTATTTTTGTGTCAGCCATCCTGCTATCTCATTTGTCCAATTAAAGCAAGGAAGAAATCCTCC ATTCTCCTTTTTTCCCCATTCTTGGATAGAATGAATGTCTATAGTGAAAAGAACTCATCAGTAGTCCTCTCAGATTTGGTCTGAATTTCA CCAAATATTTGTATAATTGCAAAAAACTTGTTTCTCAGCCTTCTCCTTTAGGGGGAAAACAAATAGAGGGCATGATGGCCTACCTCCCTG >98431_98431_7_VPS41-CEP41_VPS41_chr7_38794302_ENST00000395969_CEP41_chr7_130067859_ENST00000489512_length(amino acids)=614AA_BP=571 MAEAEEQETGSLEESTDESEEEESEEEPKLKYERLSNGVTEILQKDAASCMTVHDKFLALGTHYGKVYLLDVQGNITQKFDVVQVFGLYS GEEFHETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGEGNIRSVKWRGHLIAWANNMGVKIFDIISKQRITN VPRDDISLRPDMYPCSLCWKDNVTLIIGWGTSVKVCSVKERHASEMRDLPSRYVEIVSQFETEFYISGLAPLCDQLVVLSYVKEISEKTE REYCARPRLDIIQPLSETCEEISSDALTVRGFQENECRDYHLEYSEGESLFYIVSPRDVVVAKERDQDDHIDWLLEKKKYEEALMAAEIS QKNIKRHKILDIGLAYINHLVERGDYDIAARKCQKILGKNAALWEYEVYKFKEIGQLKAISPYLPRGDPVLKPLIYEMILHEFLESDYEG FATLIREWPGDLYNNSVIVQAVRDHLKKDSQNKTLLKTLAELYTYDKNYGNALEIYLTLRHKDVFQLIHKHNLFSSIKDKIVLLMDFDSE -------------------------------------------------------------- >98431_98431_8_VPS41-CEP41_VPS41_chr7_38794302_ENST00000395969_CEP41_chr7_130067859_ENST00000541543_length(transcript)=2898nt_BP=1713nt ATGGCGGAAGCAGAGGAGCAGGAAACTGGGTCCCTTGAAGAATCTACAGATGAGTCTGAGGAAGAAGAGAGCGAAGAGGAACCCAAGCTG AAGTATGAAAGGCTTTCCAATGGGGTAACTGAAATACTTCAGAAGGATGCAGCTAGCTGCATGACAGTCCATGACAAGTTTTTGGCATTG GGCACACATTATGGCAAGGTTTATTTACTTGATGTCCAGGGGAACATCACTCAGAAGTTTGATGTAGTGCAGGTATTTGGACTGTATTCT GGAGAAGAATTTCACGAGACTTTTGACTGTCCCATTAAAATTATTGCTGTGCACCCACATTTCGTGAGATCCAGTTGCAAGCAGTTTGTG ACCGGAGGGAAGAAGCTGCTACTGTTTGAACGGTCTTGGATGAACAGATGGAAGTCTGCTGTTCTGCATGAAGGGGAAGGGAACATAAGG AGTGTGAAGTGGAGAGGCCATCTGATTGCTTGGGCCAATAATATGGGTGTGAAGATTTTTGACATCATCTCAAAGCAAAGAATCACCAAT GTGCCCCGGGATGATATAAGTCTTCGCCCAGACATGTATCCCTGCAGCCTCTGCTGGAAGGACAATGTGACACTGATTATTGGCTGGGGG ACTTCTGTCAAGGTGTGCTCAGTGAAGGAACGGCATGCCAGTGAAATGAGGGATTTGCCAAGTCGATATGTTGAAATAGTGTCTCAGTTT GAAACTGAATTCTACATCAGTGGACTTGCACCTCTCTGTGATCAGCTTGTTGTACTTTCGTATGTAAAGGAGATTTCAGAAAAAACGGAA AGAGAATACTGTGCCAGGCCTAGACTGGACATCATCCAGCCACTTTCTGAGACTTGTGAAGAGATCTCTTCTGATGCTTTGACAGTCAGA GGCTTTCAGGAGAATGAATGTAGAGATTATCATTTAGAATACTCTGAAGGGGAATCACTTTTTTACATCGTGAGTCCGAGAGATGTTGTA GTGGCCAAGGAACGAGACCAAGATGATCACATTGACTGGCTCCTTGAAAAGAAGAAATATGAAGAAGCATTGATGGCAGCTGAAATTAGC CAAAAAAATATTAAAAGACATAAGATTCTGGATATTGGCTTGGCATATATAAATCACCTGGTGGAGAGAGGAGACTATGACATAGCAGCA CGCAAATGCCAGAAAATTCTTGGGAAAAATGCAGCACTCTGGGAATATGAAGTTTATAAATTTAAAGAAATTGGACAGCTTAAGGCTATT AGTCCTTATTTGCCAAGAGGTGATCCAGTTCTGAAACCACTCATCTATGAAATGATCTTACATGAATTTTTGGAGAGTGATTATGAGGGT TTTGCCACATTGATCCGAGAATGGCCTGGAGATCTGTATAATAATTCAGTCATAGTTCAAGCAGTTCGGGATCATTTGAAGAAAGATAGT CAGAACAAGACTTTACTTAAAACCCTGGCAGAATTGTACACCTATGACAAGAACTATGGCAATGCTCTGGAAATATACTTAACATTAAGA CATAAAGACGTTTTTCAGTTGATCCACAAGCATAATCTTTTCAGTTCTATCAAGGATAAAATTGTTTTATTAATGGATTTTGATTCAGAG AAAGCTGTTGACATGCTTTTGGACAATGAAGATAAAATTTCAATTAAAAAGGTAGTGGAAGAATTGGAAGACAGACCAGAGCTACAGCAT GTGTATCTGATGAAAAGGATACCACAGAACCCAAGATACCAGCATATCAAATCAAGACTGGACACTGATTATAGATACAAAAAAGATGAG CTTTTCAAGAGACTAAAAGTTACAACTTTTGCCCAGCTGATCATCCAAGTTGCTTCCCTCTCTGATCAAACACTGGAAGTGACAGCTGAG GAGATTCAAAGGCTGGAAGACAATGATTCTGCAGCTTCAGACCCTGATGCTGAAACCACTGCCAGGACCAATGGGAAAGGAAATCCAGGT GAGCAGTCGCCGAGCCCTGAGCAGTTCATAAACAACGCAGGAGCAGGGGACTCCAGCCGCTCAACTCTTCAGAGTGTCATCAGTGGTGTT GGGGAACTGGATCTAGACAAAGGGCCAGTGAAGAAAGCAGAGCCCCATACCAAAGACAAACCTTATCCTGACTGCCCCTTCCTGCTGCTA GATGTGCGTGATAGAGATTCTTACCAGCAGTGCCACATTGTTGGAGCTTACAGTTACCCAATTGCAACTCTGTCTAGAACAATGAACCCT TATTCAAATGATATTCTTGAATATAAAAATGCCCATGGCAAGATCATCATTCTGTATGACGATGATGAAAGGCTGGCCAGTCAGGCGGCC ACCACCATGTGCGAGCGTGGATTTGAAAACCTCTTCATGCTTTCCGGAGGCCGACTGAACCAAGCTAACTCCTCCGGAAGAGAGTCCAAG GTGCCTGGTGCCCGAAGCGCTCAGAATCTGCCAGGTGGCGGCCCCGCCAGCCACTCAAACCCCCGCTCCCTCAGCAGTGGTCACCTGCAA GGCAAACCCTGGAAGTAAAGACTTTGTCTCACTTAGGCAAATAAATGTTCTTCCTCTTTTCAGAACCCCTGAGCATTTCCCAAGTTGGGT CATTTCCAGAAACTTCTGCAGAGGAAAGACCATGACATATGTATGGGATAGGCCTCTTCCCTGTCCCTGTCTCCAGTTCCTCTCCCCTCA GGAGGCCACCTCAGGAAGGATTTTGACAGGTGACCATAAAAACCAGAGGTGTGACAGGCTCTAGTCTCCTCCCTGTTGTTTACAGCATAT TTAAGTCTTGTGAAACTGTATAGGAAAAAAGTATCTACGTTTTTAGTTTTTTTGTTTTGTTTTTTTTTAATAAGGTCCAGCTTGTTGGGT >98431_98431_8_VPS41-CEP41_VPS41_chr7_38794302_ENST00000395969_CEP41_chr7_130067859_ENST00000541543_length(amino acids)=845AA_BP=571 MAEAEEQETGSLEESTDESEEEESEEEPKLKYERLSNGVTEILQKDAASCMTVHDKFLALGTHYGKVYLLDVQGNITQKFDVVQVFGLYS GEEFHETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGEGNIRSVKWRGHLIAWANNMGVKIFDIISKQRITN VPRDDISLRPDMYPCSLCWKDNVTLIIGWGTSVKVCSVKERHASEMRDLPSRYVEIVSQFETEFYISGLAPLCDQLVVLSYVKEISEKTE REYCARPRLDIIQPLSETCEEISSDALTVRGFQENECRDYHLEYSEGESLFYIVSPRDVVVAKERDQDDHIDWLLEKKKYEEALMAAEIS QKNIKRHKILDIGLAYINHLVERGDYDIAARKCQKILGKNAALWEYEVYKFKEIGQLKAISPYLPRGDPVLKPLIYEMILHEFLESDYEG FATLIREWPGDLYNNSVIVQAVRDHLKKDSQNKTLLKTLAELYTYDKNYGNALEIYLTLRHKDVFQLIHKHNLFSSIKDKIVLLMDFDSE KAVDMLLDNEDKISIKKVVEELEDRPELQHVYLMKRIPQNPRYQHIKSRLDTDYRYKKDELFKRLKVTTFAQLIIQVASLSDQTLEVTAE EIQRLEDNDSAASDPDAETTARTNGKGNPGEQSPSPEQFINNAGAGDSSRSTLQSVISGVGELDLDKGPVKKAEPHTKDKPYPDCPFLLL DVRDRDSYQQCHIVGAYSYPIATLSRTMNPYSNDILEYKNAHGKIIILYDDDERLASQAATTMCERGFENLFMLSGGRLNQANSSGRESK -------------------------------------------------------------- |
Top |
Fusion Gene PPI Analysis for VPS41-CEP41 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| Hgene | VPS41 | chr7:38794302 | chr7:130067859 | ENST00000310301 | - | 21 | 29 | 1_540 | 596.0 | 855.0 | ARL8B |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Top |
Related Drugs for VPS41-CEP41 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
Related Diseases for VPS41-CEP41 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2021-Present -The University of Texas Health Science Center at Houston (UTHealth)
Web File Viewing | Emergency Information |Campus Carry|Site Policies