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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:VPS41-SDK1 (FusionGDB2 ID:98440) |
Fusion Gene Summary for VPS41-SDK1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: VPS41-SDK1 | Fusion gene ID: 98440 | Hgene | Tgene | Gene symbol | VPS41 | SDK1 | Gene ID | 27072 | 221935 |
| Gene name | VPS41 subunit of HOPS complex | sidekick cell adhesion molecule 1 | |
| Synonyms | HVPS41|HVSP41|hVps41p | - | |
| Cytomap | 7p14.1 | 7p22.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | vacuolar protein sorting-associated protein 41 homologS53VPS41, HOPS complex subunitvacuolar assembly protein 41vacuolar protein sorting 41 homolog | protein sidekick-1sidekick homolog 1, cell adhesion molecule | |
| Modification date | 20200313 | 20200320 | |
| UniProtAcc | . | . | |
| Ensembl transtripts involved in fusion gene | ENST00000310301, ENST00000395969, ENST00000466017, | ENST00000466611, ENST00000389531, ENST00000404826, | |
| Fusion gene scores | * DoF score | 15 X 14 X 9=1890 | 21 X 21 X 9=3969 |
| # samples | 17 | 23 | |
| ** MAII score | log2(17/1890*10)=-3.47477958297073 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(23/3969*10)=-4.10906979605546 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: VPS41 [Title/Abstract] AND SDK1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | VPS41(38835065)-SDK1(4150295), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene breakpoints across VPS41 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across SDK1 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | LGG | TCGA-DU-6399-01A | VPS41 | chr7 | 38835065 | - | SDK1 | chr7 | 4150295 | + |
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Fusion Gene ORF analysis for VPS41-SDK1 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000310301 | ENST00000466611 | VPS41 | chr7 | 38835065 | - | SDK1 | chr7 | 4150295 | + |
| 5CDS-intron | ENST00000395969 | ENST00000466611 | VPS41 | chr7 | 38835065 | - | SDK1 | chr7 | 4150295 | + |
| 5UTR-3CDS | ENST00000466017 | ENST00000389531 | VPS41 | chr7 | 38835065 | - | SDK1 | chr7 | 4150295 | + |
| 5UTR-3CDS | ENST00000466017 | ENST00000404826 | VPS41 | chr7 | 38835065 | - | SDK1 | chr7 | 4150295 | + |
| 5UTR-intron | ENST00000466017 | ENST00000466611 | VPS41 | chr7 | 38835065 | - | SDK1 | chr7 | 4150295 | + |
| In-frame | ENST00000310301 | ENST00000389531 | VPS41 | chr7 | 38835065 | - | SDK1 | chr7 | 4150295 | + |
| In-frame | ENST00000310301 | ENST00000404826 | VPS41 | chr7 | 38835065 | - | SDK1 | chr7 | 4150295 | + |
| In-frame | ENST00000395969 | ENST00000389531 | VPS41 | chr7 | 38835065 | - | SDK1 | chr7 | 4150295 | + |
| In-frame | ENST00000395969 | ENST00000404826 | VPS41 | chr7 | 38835065 | - | SDK1 | chr7 | 4150295 | + |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000310301 | VPS41 | chr7 | 38835065 | - | ENST00000404826 | SDK1 | chr7 | 4150295 | + | 7706 | 772 | 55 | 4089 | 1344 |
| ENST00000310301 | VPS41 | chr7 | 38835065 | - | ENST00000389531 | SDK1 | chr7 | 4150295 | + | 5054 | 772 | 55 | 4029 | 1324 |
| ENST00000395969 | VPS41 | chr7 | 38835065 | - | ENST00000404826 | SDK1 | chr7 | 4150295 | + | 7576 | 642 | 0 | 3959 | 1319 |
| ENST00000395969 | VPS41 | chr7 | 38835065 | - | ENST00000389531 | SDK1 | chr7 | 4150295 | + | 4924 | 642 | 0 | 3899 | 1299 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000310301 | ENST00000404826 | VPS41 | chr7 | 38835065 | - | SDK1 | chr7 | 4150295 | + | 0.000583554 | 0.9994165 |
| ENST00000310301 | ENST00000389531 | VPS41 | chr7 | 38835065 | - | SDK1 | chr7 | 4150295 | + | 0.00143207 | 0.99856794 |
| ENST00000395969 | ENST00000404826 | VPS41 | chr7 | 38835065 | - | SDK1 | chr7 | 4150295 | + | 0.000611678 | 0.99938834 |
| ENST00000395969 | ENST00000389531 | VPS41 | chr7 | 38835065 | - | SDK1 | chr7 | 4150295 | + | 0.001544057 | 0.9984559 |
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Fusion Genomic Features for VPS41-SDK1 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| VPS41 | chr7 | 38835064 | - | SDK1 | chr7 | 4150294 | + | 0.00011309 | 0.9998869 |
| VPS41 | chr7 | 38835064 | - | SDK1 | chr7 | 4150294 | + | 0.00011309 | 0.9998869 |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for VPS41-SDK1 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr7:38835065/chr7:4150295) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | . |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | VPS41 | chr7:38835065 | chr7:4150295 | ENST00000310301 | - | 9 | 29 | 18_27 | 239 | 855.0 | Compositional bias | Note=Poly-Glu |
| Tgene | SDK1 | chr7:38835065 | chr7:4150295 | ENST00000404826 | 21 | 45 | 1176_1274 | 1108 | 2214.0 | Domain | Fibronectin type-III 6 | |
| Tgene | SDK1 | chr7:38835065 | chr7:4150295 | ENST00000404826 | 21 | 45 | 1279_1376 | 1108 | 2214.0 | Domain | Fibronectin type-III 7 | |
| Tgene | SDK1 | chr7:38835065 | chr7:4150295 | ENST00000404826 | 21 | 45 | 1380_1474 | 1108 | 2214.0 | Domain | Fibronectin type-III 8 | |
| Tgene | SDK1 | chr7:38835065 | chr7:4150295 | ENST00000404826 | 21 | 45 | 1479_1576 | 1108 | 2214.0 | Domain | Fibronectin type-III 9 | |
| Tgene | SDK1 | chr7:38835065 | chr7:4150295 | ENST00000404826 | 21 | 45 | 1581_1699 | 1108 | 2214.0 | Domain | Fibronectin type-III 10 | |
| Tgene | SDK1 | chr7:38835065 | chr7:4150295 | ENST00000404826 | 21 | 45 | 1704_1800 | 1108 | 2214.0 | Domain | Fibronectin type-III 11 | |
| Tgene | SDK1 | chr7:38835065 | chr7:4150295 | ENST00000404826 | 21 | 45 | 1804_1899 | 1108 | 2214.0 | Domain | Fibronectin type-III 12 | |
| Tgene | SDK1 | chr7:38835065 | chr7:4150295 | ENST00000404826 | 21 | 45 | 1902_2000 | 1108 | 2214.0 | Domain | Fibronectin type-III 13 | |
| Tgene | SDK1 | chr7:38835065 | chr7:4150295 | ENST00000404826 | 21 | 45 | 2207_2213 | 1108 | 2214.0 | Motif | PDZ-binding | |
| Tgene | SDK1 | chr7:38835065 | chr7:4150295 | ENST00000404826 | 21 | 45 | 2031_2213 | 1108 | 2214.0 | Topological domain | Cytoplasmic | |
| Tgene | SDK1 | chr7:38835065 | chr7:4150295 | ENST00000404826 | 21 | 45 | 2010_2030 | 1108 | 2214.0 | Transmembrane | Helical |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | VPS41 | chr7:38835065 | chr7:4150295 | ENST00000310301 | - | 9 | 29 | 568_712 | 239 | 855.0 | Repeat | Note=CHCR |
| Hgene | VPS41 | chr7:38835065 | chr7:4150295 | ENST00000310301 | - | 9 | 29 | 791_839 | 239 | 855.0 | Zinc finger | RING-type%3B atypical |
| Tgene | SDK1 | chr7:38835065 | chr7:4150295 | ENST00000404826 | 21 | 45 | 19_58 | 1108 | 2214.0 | Compositional bias | Note=Pro-rich | |
| Tgene | SDK1 | chr7:38835065 | chr7:4150295 | ENST00000404826 | 21 | 45 | 104_186 | 1108 | 2214.0 | Domain | Note=Ig-like C2-type 1 | |
| Tgene | SDK1 | chr7:38835065 | chr7:4150295 | ENST00000404826 | 21 | 45 | 1072_1171 | 1108 | 2214.0 | Domain | Fibronectin type-III 5 | |
| Tgene | SDK1 | chr7:38835065 | chr7:4150295 | ENST00000404826 | 21 | 45 | 191_277 | 1108 | 2214.0 | Domain | Note=Ig-like C2-type 2 | |
| Tgene | SDK1 | chr7:38835065 | chr7:4150295 | ENST00000404826 | 21 | 45 | 293_378 | 1108 | 2214.0 | Domain | Note=Ig-like C2-type 3 | |
| Tgene | SDK1 | chr7:38835065 | chr7:4150295 | ENST00000404826 | 21 | 45 | 386_476 | 1108 | 2214.0 | Domain | Note=Ig-like C2-type 4 | |
| Tgene | SDK1 | chr7:38835065 | chr7:4150295 | ENST00000404826 | 21 | 45 | 480_569 | 1108 | 2214.0 | Domain | Note=Ig-like C2-type 5 | |
| Tgene | SDK1 | chr7:38835065 | chr7:4150295 | ENST00000404826 | 21 | 45 | 574_663 | 1108 | 2214.0 | Domain | Note=Ig-like C2-type 6 | |
| Tgene | SDK1 | chr7:38835065 | chr7:4150295 | ENST00000404826 | 21 | 45 | 670_766 | 1108 | 2214.0 | Domain | Fibronectin type-III 1 | |
| Tgene | SDK1 | chr7:38835065 | chr7:4150295 | ENST00000404826 | 21 | 45 | 771_867 | 1108 | 2214.0 | Domain | Fibronectin type-III 2 | |
| Tgene | SDK1 | chr7:38835065 | chr7:4150295 | ENST00000404826 | 21 | 45 | 872_970 | 1108 | 2214.0 | Domain | Fibronectin type-III 3 | |
| Tgene | SDK1 | chr7:38835065 | chr7:4150295 | ENST00000404826 | 21 | 45 | 974_1068 | 1108 | 2214.0 | Domain | Fibronectin type-III 4 |
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Fusion Gene Sequence for VPS41-SDK1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >98440_98440_1_VPS41-SDK1_VPS41_chr7_38835065_ENST00000310301_SDK1_chr7_4150295_ENST00000389531_length(transcript)=5054nt_BP=772nt AAGTGTGTGGTTTCCTCTTATTTCCGGGTCTGTCAGGTGACTCTCCCGTGGCGCCATGGCGGAAGCAGAGGAGCAGGAAACTGGGTCCCT TGAAGAATCTACAGATGAGTCTGAGGAAGAAGAGAGCGAAGAGGAACCCAAGCTGAAGTATGAAAGGCTTTCCAATGGGGTAACTGAAAT ACTTCAGAAGGATGCAGCTAGCTGCATGACAGTCCATGACAAGTTTTTGGCATTGGGCACACATTATGGCAAGGTTTATTTACTTGATGT CCAGGGGAACATCACTCAGAAGTTTGATGTAAGTCCTGTGAAGATAAATCAGATTAGCTTGGATGAAAGTGGAGAGCACATGGGTGTGTG TTCAGAGGATGGCAAGGTGCAGGTATTTGGACTGTATTCTGGAGAAGAATTTCACGAGACTTTTGACTGTCCCATTAAAATTATTGCTGT GCACCCACATTTCGTGAGATCCAGTTGCAAGCAGTTTGTGACCGGAGGGAAGAAGCTGCTACTGTTTGAACGGTCTTGGATGAACAGATG GAAGTCTGCTGTTCTGCATGAAGGGGAAGGGAACATAAGGAGTGTGAAGTGGAGAGGCCATCTGATTGCTTGGGCCAATAATATGGGTGT GAAGATTTTTGACATCATCTCAAAGCAAAGAATCACCAATGTGCCCCGGGATGATATAAGTCTTCGCCCAGACATGTATCCCTGCAGCCT CTGCTGGAAGGACAATGTGACACTGATTATTGGCTGGGGGACTTCTGTCAAGGTGGGAGCTATCGGCGACGAGGAGGAGTGGGTCACCCT CTATGAAGAGGAGAATGAGCCTGATGCCCAGATGCTGGAGATCCCAAACCTCACACCCTACACTCACTACAGATTTCGAATGAAGCAAGT GAACATTGTTGGGCCGAGCCCCTACAGTCCGTCTTCCCGGGTCATCCAGACCCTGCAGGCCCCACCCGACGTGGCTCCAACCAGCGTCAC GGTCCGTACTGCCAGTGAGACCAGCCTGCGGCTTCGCTGGGTGCCCCTGCCGGATTCTCAGTACAACGGGAACCCCGAGTCCGTGGGCTA CAGGATTAAGTACTGGCGCTCAGACCTCCAGTCCTCAGCAGTGGCCCAAGTCGTCAGTGACCGGCTGGAGAGAGAATTCACCATCGAGGA GCTGGAGGAGTGGATGGAATACGAGCTGCAGATGCAGGCCTTCAACGCCGTCGGGGCTGGGCCGTGGAGCGAGGTGGTGCGGGGCCGGAC GCGGGAGTCAGTTCCTTCAGCCGCCCCTGAGAACGTGTCAGCCGAGGCTGTCAGCTCGACCCAGATTTTACTGACATGGACATCCGTGCC GGAACAGGACCAGAATGGGCTCATACTGGGCTACAAGATCCTGTTCCGGGCCAAAGACCTGGATCCCGAGCCCAGGAGCCACATCGTGCG AGGGAACCACACGCAGTCGGCCCTGCTGGCAGGCCTGCGCAAGTTCGTGCTCTACGAGCTCCAGGTGCTGGCGTTCACCCGCATCGGGAA CGGGGTCCCCAGCACGCCCCTCATCCTGGAGCGCACCAAAGACGATGCCCCAGGCCCACCAGTGAGGCTCGTGTTCCCCGAAGTGAGACT CACCTCCGTGCGGATAGTGTGGCAACCTCCGGAGGAGCCCAACGGCATCATCCTGGGGTACCAGATTGCCTACCGCCTGGCCAGCAGCAG CCCCCACACCTTCACCACCGTGGAGGTCGGCGCCACAGTGAGGCAGTTCACAGCCACCGACCTGGCCCCGGAGTCCGCATACATCTTCAG GCTGTCCGCCAAGACGAGGCAGGGCTGGGGGGAGCCACTGGAGGCCACCGTCATCACCACCGAGAAGAGAGAGCGGCCGGCACCCCCCAG AGAGCTCCTGGTGCCCCAGGCAGAAGTGACCGCACGCAGCCTCCGGCTCCAGTGGGTCCCGGGCAGCGACGGGGCCTCCCCCATCCGGTA CTTCACCATGCAGGTGCGAGAGCTGCCTCGGGGTGAGTGGCAGACCTACTCCTCGTCCATCAGCCATGAGGCGACAGCATGCGTCGTTGA CAGACTGAGGCCCTTCACCTCCTACAAGCTGCGCCTGAAAGCCACCAACGACATTGGGGACAGTGACTTCAGTTCAGAGACAGAGGCGGT GACCACGCTGCAGGATGTTCCAGGAGAGCCCCCGGGATCTGTCTCAGCGACGCCACACACCACGTCCTCTGTCCTGATACAGTGGCAGCC TCCGAGGGACGAAAGCCTGAATGGCCTTCTTCAGGGATACAGGATCTACTACAGGGAGCTGGAGTATGAAGCCGGGTCAGGCACTGAGGC CAAGACGCTCAAAAACCCTATAGCTTTACATGCTGAGCTCACAGATTTAAAGAAGTACCGGCGCTATGAAGTAATAATGACCGCCTATAA CATCATCGGCGAGAGCCCAGCCAGCGCGCCCGTGGAGGTCTTTGTCGGCGAGGCTGCCCCGGCCATGGCCCCGCAGAACGTGCAGGTGAC CCCACTCACGGCCAGCCAGCTGGAGGTCACGTGGGACCCACCACCCCCGGAGAGCCAGAATGGGAACATCCAAGGCTACAAGATTTACTA CTGGGAGGCAGACAGCCAGAACGAAACGGAGAAAATGAAGGTCCTCTTCCTCCCCGAGCCCGTGGTGAGGCTGAAGAACCTGACCAGCCA TACCAAGTACCTGGTCAGCATATCAGCCTTCAACGCCGCCGGAGATGGACCTAAGAGTGACCCCCAGCAGGGGCGCACCCACCAGGCCGC CCCTGGGGCCCCCAGCTTTCTGGCGTTCTCAGAAATAACCTCCACCACGCTCAACGTGTCCTGGGGCGAGCCTGCGGCGGCCAACGGCAT CCTGCAGGGCTATCGGGTGGTGTACGAGCCCTTGGCCCCTGTACAAGGGGTGAGCAAGGTGGTGACCGTGGAAGTGAGAGGGAACTGGCA GCGCTGGCTGAAGGTGCGGGACCTCACCAAGGGAGTGACCTATTTCTTCCGTGTCCAAGCGCGGACCATCACCTACGGGCCCGAGCTCCA AGCCAATATCACAGCCGGGCCAGCCGAGGGATCCCCGGGCTCGCCTAGAGATGTCCTGGTCACCAAGTCCGCCTCTGAACTGACGCTGCA GTGGACTGAGGGACACTCTGGCGACACACCTACCACGGGCTATGTGATCGAGGCCCGGCCCTCAGATGAAGGCTTATGGGACATGTTTGT GAAGGACATCCCGCGGAGCGCCACATCCTACACCCTCAGCCTGGATAAGCTCCGGCAAGGAGTGACTTACGAGTTCCGGGTGGTGGCTGT GAATGAGGCGGGCTACGGGGAGCCCAGCAACCCCTCCACGGCTGTGTCAGCTCAAGTGGAAGCCCCATTCTACGAGGAGTGGTGGTTCCT CCTGGTGATGGCTCTGTCCAGCCTGATCGTCATCCTGCTGGTGGTGTTCGCCCTCGTCCTGCACGGGCAGAATAAGAAGTATAAGAACTG CAGCACAGGAAAGGGGATCTCCACCATGGAGGAGTCTGTGACCCTGGACAACGGAGGATTTGCTGCCCTGGAGCTCAGCAGCCGCCACCT CAATGTCAAGAGCACCTTCTCCAAGAAGAACGGGACCAGGTCCCCACCCCGGCCTAGCCCCGGCGGCCTGCACTACTCAGACGAGGACAT CTGCAACAAGTACAACGGCGCCGTGCTGACCGAGAGCGTGAGCCTCAAGGAGAAGTCGGCAGATGCATCAGAATCTGAGGCCACGGACTC TGACTACGAGGACGCGCTGCCCAAGCACTCCTTCGTGAACCACTACATGAGCGACCCCACCTACTACAACTCATGGAAGCGCAGGGCCCA GGGCCGCGCACCTGCGCCGCACAGGTACGAGGCGGTGGCGGGCTCCGAGGCGGGCGCGCAGCTGCACCCGGTCATCACCACGCAGAGCGC GGGCGGCGTCTACACCCCCGCTGGCCCCGGCGCGCGAACTCCGCTCACCGGCTTCTCCTCCTTCGTGTGAGCAAAGCGCCGCGCCTCCCT CAGGGCGGAACGGAGGCAACTTTCCGGAGTCTATTTTTGTTAAGACAATCAACTCCAATAACTGAGCTGAAGTTTTTGTTTAAAAAGAAA AAAATCTGATAAGTGATGATTTTACCTACTTGTGGACACTAGATTTCAATTAGGAAGGTTTTTTTAAACGGCTTTTTGTAACTTCGCTGC AGGAAGCAGGTTTGTTTCTTTTTCTTTTCTTTTTAAGAGAAGGTGTATTTCACTGGTGCAATGGCTTGGCACCTCCGGGGCCTGGGAGGA CCTCAGACCTCCCCAGCCCTGGGTTTCTCCGTCTTCAAGACCAACTAGGAAGGGTCAAGCGGGGAGAGGGAGTGGAGGGTCAGGTGAGAT CTCAGAGCTGCCCCGGCCGGCCCCCGTCTCTTTCTACCTCCTCTTCCAGAGAACCAGCGGCTCACACCCTTCTCAACGCAGGACATCCTC GGCGGCTCCTGGGGTTTGAAGAGCAAACGTTTTTCCCTGGGCTCAGTGCGTTTTGTCCCAACTTCATCTGTTTCTGAAATGTTCTCACTT GGCAGTGTCTAGTCAAGGAGTCGGCTTTCAGGTTCCTGACGGCCAGGCAGGGATGCTAAGGTGTGGCTCAGCCGTCACTGTCTGTGTCAC TGCAGTGGTGCGGTCCTCAGGCTTTTCTGCCTGTCTTTCCCCCTTCCTTCTCACCTGACAGCGAGGGAGAGGGAAGCCTCTTAGGGCTGG AAGCCACCACGCTGGCCCTCTCCTTCCCCGAACACAGCACACGGTCAACTCCGCGGGACACGAGGACACGGGACGGCGTCTCCAGAATTG CTTGTTACGTAGGAAGCGTGCATTGTTAACCAGAGTATTTTTAAAATCTTTTTATCTTTTTTTAAACTATGTCACATGAAATGAATGCGT CTTTGCTGTCTCCAGGTGCCTTTTTATTAATTGTTCAGCTTTGTACATGGGAAAGATGAAAAGCAACAGTGTCTGCAAATAAAGCAAAAC >98440_98440_1_VPS41-SDK1_VPS41_chr7_38835065_ENST00000310301_SDK1_chr7_4150295_ENST00000389531_length(amino acids)=1324AA_BP=239 MAEAEEQETGSLEESTDESEEEESEEEPKLKYERLSNGVTEILQKDAASCMTVHDKFLALGTHYGKVYLLDVQGNITQKFDVSPVKINQI SLDESGEHMGVCSEDGKVQVFGLYSGEEFHETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGEGNIRSVKWR GHLIAWANNMGVKIFDIISKQRITNVPRDDISLRPDMYPCSLCWKDNVTLIIGWGTSVKVGAIGDEEEWVTLYEEENEPDAQMLEIPNLT PYTHYRFRMKQVNIVGPSPYSPSSRVIQTLQAPPDVAPTSVTVRTASETSLRLRWVPLPDSQYNGNPESVGYRIKYWRSDLQSSAVAQVV SDRLEREFTIEELEEWMEYELQMQAFNAVGAGPWSEVVRGRTRESVPSAAPENVSAEAVSSTQILLTWTSVPEQDQNGLILGYKILFRAK DLDPEPRSHIVRGNHTQSALLAGLRKFVLYELQVLAFTRIGNGVPSTPLILERTKDDAPGPPVRLVFPEVRLTSVRIVWQPPEEPNGIIL GYQIAYRLASSSPHTFTTVEVGATVRQFTATDLAPESAYIFRLSAKTRQGWGEPLEATVITTEKRERPAPPRELLVPQAEVTARSLRLQW VPGSDGASPIRYFTMQVRELPRGEWQTYSSSISHEATACVVDRLRPFTSYKLRLKATNDIGDSDFSSETEAVTTLQDVPGEPPGSVSATP HTTSSVLIQWQPPRDESLNGLLQGYRIYYRELEYEAGSGTEAKTLKNPIALHAELTDLKKYRRYEVIMTAYNIIGESPASAPVEVFVGEA APAMAPQNVQVTPLTASQLEVTWDPPPPESQNGNIQGYKIYYWEADSQNETEKMKVLFLPEPVVRLKNLTSHTKYLVSISAFNAAGDGPK SDPQQGRTHQAAPGAPSFLAFSEITSTTLNVSWGEPAAANGILQGYRVVYEPLAPVQGVSKVVTVEVRGNWQRWLKVRDLTKGVTYFFRV QARTITYGPELQANITAGPAEGSPGSPRDVLVTKSASELTLQWTEGHSGDTPTTGYVIEARPSDEGLWDMFVKDIPRSATSYTLSLDKLR QGVTYEFRVVAVNEAGYGEPSNPSTAVSAQVEAPFYEEWWFLLVMALSSLIVILLVVFALVLHGQNKKYKNCSTGKGISTMEESVTLDNG GFAALELSSRHLNVKSTFSKKNGTRSPPRPSPGGLHYSDEDICNKYNGAVLTESVSLKEKSADASESEATDSDYEDALPKHSFVNHYMSD -------------------------------------------------------------- >98440_98440_2_VPS41-SDK1_VPS41_chr7_38835065_ENST00000310301_SDK1_chr7_4150295_ENST00000404826_length(transcript)=7706nt_BP=772nt AAGTGTGTGGTTTCCTCTTATTTCCGGGTCTGTCAGGTGACTCTCCCGTGGCGCCATGGCGGAAGCAGAGGAGCAGGAAACTGGGTCCCT TGAAGAATCTACAGATGAGTCTGAGGAAGAAGAGAGCGAAGAGGAACCCAAGCTGAAGTATGAAAGGCTTTCCAATGGGGTAACTGAAAT ACTTCAGAAGGATGCAGCTAGCTGCATGACAGTCCATGACAAGTTTTTGGCATTGGGCACACATTATGGCAAGGTTTATTTACTTGATGT CCAGGGGAACATCACTCAGAAGTTTGATGTAAGTCCTGTGAAGATAAATCAGATTAGCTTGGATGAAAGTGGAGAGCACATGGGTGTGTG TTCAGAGGATGGCAAGGTGCAGGTATTTGGACTGTATTCTGGAGAAGAATTTCACGAGACTTTTGACTGTCCCATTAAAATTATTGCTGT GCACCCACATTTCGTGAGATCCAGTTGCAAGCAGTTTGTGACCGGAGGGAAGAAGCTGCTACTGTTTGAACGGTCTTGGATGAACAGATG GAAGTCTGCTGTTCTGCATGAAGGGGAAGGGAACATAAGGAGTGTGAAGTGGAGAGGCCATCTGATTGCTTGGGCCAATAATATGGGTGT GAAGATTTTTGACATCATCTCAAAGCAAAGAATCACCAATGTGCCCCGGGATGATATAAGTCTTCGCCCAGACATGTATCCCTGCAGCCT CTGCTGGAAGGACAATGTGACACTGATTATTGGCTGGGGGACTTCTGTCAAGGTGGGAGCTATCGGCGACGAGGAGGAGTGGGTCACCCT CTATGAAGAGGAGAATGAGCCTGATGCCCAGATGCTGGAGATCCCAAACCTCACACCCTACACTCACTACAGATTTCGAATGAAGCAAGT GAACATTGTTGGGCCGAGCCCCTACAGTCCGTCTTCCCGGGTCATCCAGACCCTGCAGGCCCCACCCGACGTGGCTCCAACCAGCGTCAC GGTCCGTACTGCCAGTGAGACCAGCCTGCGGCTTCGCTGGGTGCCCCTGCCGGATTCTCAGTACAACGGGAACCCCGAGTCCGTGGGCTA CAGGATTAAGTACTGGCGCTCAGACCTCCAGTCCTCAGCAGTGGCCCAAGTCGTCAGTGACCGGCTGGAGAGAGAATTCACCATCGAGGA GCTGGAGGAGTGGATGGAATACGAGCTGCAGATGCAGGCCTTCAACGCCGTCGGGGCTGGGCCGTGGAGCGAGGTGGTGCGGGGCCGGAC GCGGGAGTCAGTTCCTTCAGCCGCCCCTGAGAACGTGTCAGCCGAGGCTGTCAGCTCGACCCAGATTTTACTGACATGGACATCCGTGCC GGAACAGGACCAGAATGGGCTCATACTGGGCTACAAGATCCTGTTCCGGGCCAAAGACCTGGATCCCGAGCCCAGGAGCCACATCGTGCG AGGGAACCACACGCAGTCGGCCCTGCTGGCAGGCCTGCGCAAGTTCGTGCTCTACGAGCTCCAGGTGCTGGCGTTCACCCGCATCGGGAA CGGGGTCCCCAGCACGCCCCTCATCCTGGAGCGCACCAAAGACGATGCCCCAGGCCCACCAGTGAGGCTCGTGTTCCCCGAAGTGAGACT CACCTCCGTGCGGATAGTGTGGCAACCTCCGGAGGAGCCCAACGGCATCATCCTGGGGTACCAGATTGCCTACCGCCTGGCCAGCAGCAG CCCCCACACCTTCACCACCGTGGAGGTCGGCGCCACAGTGAGGCAGTTCACAGCCACCGACCTGGCCCCGGAGTCCGCATACATCTTCAG GCTGTCCGCCAAGACGAGGCAGGGCTGGGGGGAGCCACTGGAGGCCACCGTCATCACCACCGAGAAGAGAGAGCGGCCGGCACCCCCCAG AGAGCTCCTGGTGCCCCAGGCAGAAGTGACCGCACGCAGCCTCCGGCTCCAGTGGGTCCCGGGCAGCGACGGGGCCTCCCCCATCCGGTA CTTCACCATGCAGGTGCGAGAGCTGCCTCGGGGTGAGTGGCAGACCTACTCCTCGTCCATCAGCCATGAGGCGACAGCATGCGTCGTTGA CAGACTGAGGCCCTTCACCTCCTACAAGCTGCGCCTGAAAGCCACCAACGACATTGGGGACAGTGACTTCAGTTCAGAGACAGAGGCGGT GACCACGCTGCAGGATGTTCCAGGAGAGCCCCCGGGATCTGTCTCAGCGACGCCACACACCACGTCCTCTGTCCTGATACAGTGGCAGCC TCCGAGGGACGAAAGCCTGAATGGCCTTCTTCAGGGATACAGGATCTACTACAGGGAGCTGGAGTATGAAGCCGGGTCAGGCACTGAGGC CAAGACGCTCAAAAACCCTATAGCTTTACATGCTGAGCTCACAGCCCAAAGCAGCTTCAAGACGGTGAACAGCAGCTCCACATCGACGAT GTGTGAACTAACACATTTAAAGAAGTACCGGCGCTATGAAGTAATAATGACCGCCTATAACATCATCGGCGAGAGCCCAGCCAGCGCGCC CGTGGAGGTCTTTGTCGGCGAGGCTGCCCCGGCCATGGCCCCGCAGAACGTGCAGGTGACCCCACTCACGGCCAGCCAGCTGGAGGTCAC GTGGGACCCACCACCCCCGGAGAGCCAGAATGGGAACATCCAAGGCTACAAGATTTACTACTGGGAGGCAGACAGCCAGAACGAAACGGA GAAAATGAAGGTCCTCTTCCTCCCCGAGCCCGTGGTGAGGCTGAAGAACCTGACCAGCCATACCAAGTACCTGGTCAGCATATCAGCCTT CAACGCCGCCGGAGATGGACCTAAGAGTGACCCCCAGCAGGGGCGCACCCACCAGGCCGCCCCTGGGGCCCCCAGCTTTCTGGCGTTCTC AGAAATAACCTCCACCACGCTCAACGTGTCCTGGGGCGAGCCTGCGGCGGCCAACGGCATCCTGCAGGGCTATCGGGTGGTGTACGAGCC CTTGGCCCCTGTACAAGGGGTGAGCAAGGTGGTGACCGTGGAAGTGAGAGGGAACTGGCAGCGCTGGCTGAAGGTGCGGGACCTCACCAA GGGAGTGACCTATTTCTTCCGTGTCCAAGCGCGGACCATCACCTACGGGCCCGAGCTCCAAGCCAATATCACAGCCGGGCCAGCCGAGGG ATCCCCGGGCTCGCCTAGAGATGTCCTGGTCACCAAGTCCGCCTCTGAACTGACGCTGCAGTGGACTGAGGGACACTCTGGCGACACACC TACCACGGGCTATGTGATCGAGGCCCGGCCCTCAGATGAAGGCTTATGGGACATGTTTGTGAAGGACATCCCGCGGAGCGCCACATCCTA CACCCTCAGCCTGGATAAGCTCCGGCAAGGAGTGACTTACGAGTTCCGGGTGGTGGCTGTGAATGAGGCGGGCTACGGGGAGCCCAGCAA CCCCTCCACGGCTGTGTCAGCTCAAGTGGAAGCCCCATTCTACGAGGAGTGGTGGTTCCTCCTGGTGATGGCTCTGTCCAGCCTGATCGT CATCCTGCTGGTGGTGTTCGCCCTCGTCCTGCACGGGCAGAATAAGAAGTATAAGAACTGCAGCACAGGAAAGGGGATCTCCACCATGGA GGAGTCTGTGACCCTGGACAACGGAGGATTTGCTGCCCTGGAGCTCAGCAGCCGCCACCTCAATGTCAAGAGCACCTTCTCCAAGAAGAA CGGGACCAGGTCCCCACCCCGGCCTAGCCCCGGCGGCCTGCACTACTCAGACGAGGACATCTGCAACAAGTACAACGGCGCCGTGCTGAC CGAGAGCGTGAGCCTCAAGGAGAAGTCGGCAGATGCATCAGAATCTGAGGCCACGGACTCTGACTACGAGGACGCGCTGCCCAAGCACTC CTTCGTGAACCACTACATGAGCGACCCCACCTACTACAACTCATGGAAGCGCAGGGCCCAGGGCCGCGCACCTGCGCCGCACAGGTACGA GGCGGTGGCGGGCTCCGAGGCGGGCGCGCAGCTGCACCCGGTCATCACCACGCAGAGCGCGGGCGGCGTCTACACCCCCGCTGGCCCCGG CGCGCGAACTCCGCTCACCGGCTTCTCCTCCTTCGTGTGAGCAAAGCGCCGCGCCTCCCTCAGGGCGGAACGGAGGCAACTTTCCGGAGT CTATTTTTGTTAAGACAATCAACTCCAATAACTGAGCTGAAGTTTTTGTTTAAAAAGAAAAAAATCTGATAAGTGATGATTTTACCTACT TGTGGACACTAGATTTCAATTAGGAAGGTTTTTTTAAACGGCTTTTTGTAACTTCGCTGCAGGAAGCAGGTTTGTTTCTTTTTCTTTTCT TTTTAAGAGAAGGTGTATTTCACTGGTGCAATGGCTTGGCACCTCCGGGGCCTGGGAGGACCTCAGACCTCCCCAGCCCTGGGTTTCTCC GTCTTCAAGACCAACTAGGAAGGGTCAAGCGGGGAGAGGGAGTGGAGGGTCAGGTGAGATCTCAGAGCTGCCCCGGCCGGCCCCCGTCTC TTTCTACCTCCTCTTCCAGAGAACCAGCGGCTCACACCCTTCTCAACGCAGGACATCCTCGGCGGCTCCTGGGGTTTGAAGAGCAAACGT TTTTCCCTGGGCTCAGTGCGTTTTGTCCCAACTTCATCTGTTTCTGAAATGTTCTCACTTGGCAGTGTCTAGTCAAGGAGTCGGCTTTCA GGTTCCTGACGGCCAGGCAGGGATGCTAAGGTGTGGCTCAGCCGTCACTGTCTGTGTCACTGCAGTGGTGCGGTCCTCAGGCTTTTCTGC CTGTCTTTCCCCCTTCCTTCTCACCTGACAGCGAGGGAGAGGGAAGCCTCTTAGGGCTGGAAGCCACCACGCTGGCCCTCTCCTTCCCCG AACACAGCACACGGTCAACTCCGCGGGACACGAGGACACGGGACGGCGTCTCCAGAATTGCTTGTTACGTAGGAAGCGTGCATTGTTAAC CAGAGTATTTTTAAAATCTTTTTATCTTTTTTTAAACTATGTCACATGAAATGAATGCGTCTTTGCTGTCTCCAGGTGCCTTTTTATTAA TTGTTCAGCTTTGTACATGGGAAAGATGAAAAGCAACAGTGTCTGCAAATAAAGCAAAACAGCTCTGAGAACACACGCTCCCGACTCGCC TCGTGCACACCAGGCCGTCCCCTCCCTCTGTCCTGGCTTCTGCTGGCTGCTCGCAGCAGCCACCGCTTCTCCACCACTGGCGCTGCTGCT GCCCCCTCTCCCAGTCCGAGGCCAGCTTTTAGCCTTAACAGGTTTTTTGGAAATGTTTCTTTTTTTTATTTAAAATTGTCATTGTTTGGT TTAAATTTTTCAGCTAGATGAAAAGAGTATGAACTACTTTGGAAAACTTAACAGCTCAGAGATGGCCATGCCTCCAGCCCCTCACGTCAT CTTTGCAACAGACGACTGGGCTGCCATGGTCCACCCCTCAGCCCGGGTCCCGGGTCTGGATGGAACGGGAGCACTGCTGGTGCCCACTGG CGTGTGTGCCCCGGGTCCCTGTAAGTGCCCCCTCACCAGCAGCAGCGTGACACACACAAGACTCAAGACCACCCTGTCAGTGCCCCCCAG TGCACGGCAAACGGGCAGGTGCCGTTCCCCCAGTGACCTGAGGGTAGGGGACAACTGAGCAGTATCTGACCAGTGCCACCCAGGAGCCAG TCTCCTGGCCACATGCAGAAAGTGTGGCCCCTGCTTACCTAGATGTTTTGTGCACCTCCATGGGCAGAGGGTGTGGATATTGCCTGGATT CTGTGCTGTCAGCGTTGCTGAGTATGGCCCCAGGAGACCAAGGAGAGTTTTGTATAGGCTGGAAAACCCCTTTTCAGTCTTTCCAAAATT AGAGGGTATGGCAAGTTTCCTTTTTTCTCTCCTCCCTTCCTTCCCCTCCTTCCTTTCCTTTACCCCTCCTTTCCTTCCTTCCTCCCTTCC TCTCTTCTTTCCTCCCTCCCTCCCTCCTTCCCTCCCTTCCTTCCTCTCTTTCCTCCTTCCTTCCCTCCCTTCTTTCCCTCCCTCCCTTCC TCTCTCCCCTATTCCTTCTTCCTTTTCTCCTCCTTTTTCTGAGTGGAGGGGGAAATATTCTAAACCAAAAATCCTAGATGCTCTGCCCAA AGCCACTTCTGCATGAGAATCGCAACCCACAGTTCCCCGGATGAGACTCACCACAGTGGACAGTGCCACCTCCTTCCCCTCGGCCCCGGA GAGGGCGAAGTGGGCGGGAAGCCAGGATGTGAGCACTGGAATTTCTTGGAAGAGAAGCGATAAATGGAGACCATGGCCAGCGCTGCTTTC TGTGCACTCTGATGACTGCTCTCTGCAGCCATGAGGATGTGGCTTTACATGCCAGGGAGAGTGTTGAGACGTCTTAGGTTGAGGATGAGC AGATTCGAGATATGTTTGTTGCTCTCGGGTTTTCGATACAACATCATGACACTTCTGTTTCAAGCTCATGTTTTCCGTCTCCCCTCCACT CTTAGTAAACCTTGATCTGTACGGAGCGGCCTGTCCGAGGCTACGCCGGCCTCCTGGCTGCTGCTGGACTGTGCTTAGGACAGCGCCCAT GCCTCGGAGGGACTCTGTCCCATGAGAACCACCTGTGCAAAGGAACAGAGCTGGATGTTTCCAGGTAGATTTTGGCCTCCCAGAGCAATG CGGCATTTGAGAAGCAACAGTTCCTAACTCCTTATCTTCAGGGAAGGAAAAGAAAATCACAGCCTAGGAAGATGGAGGTTGGATTTTAAT CTCGGTTTTAAAAAGAGGACAAACAAAATGTCTCTAAGCCAGGCTAGATGGAATGTGCTCCCGCTCTCTCCTGCCGTGCTGAAAGTCATG CCTTGCGGATGCCTCATGACAGCAGTGGCTGAGTCTCCCCACCCACCCCCAACGTGGCTCATTTCAGATTGCTTCGGCCCCACCCTGCAA GGATGTGGTCACGGAGTGGCCAGGAGGCTCCGTCTGAGCCACAGGGATGGGTGTGCAGAGCTCCCTCCTCCTGGGGTGCCAGGGCAGAGA TTCCAGGCAGGTGAGCCCAGAGAGAGCTGCCAGGCCACACCCCCTCGGCCTCCTGCACGGCCACCTTCTGGGTGAATCGGTCCAGCCCAA GCCCCTCTCCCCAGCCTCGCCTTCAGCCTCTCTCCCAGCCTGCTTTTATAAGGCGCACTTCACTCAATGCTGTAGCCAAAAAACGAGGGG CCCCAGGGAGAGGGGACCCAGATGGCCACACACGGAACGCGCCTCCACAGCCCCGGGAGGTGGCTCACTCTGTACAGGTCTTCGGAGGCC GTGTTTGTATCTAACTGTGACTGGGCTGAAGCATGATGTTTGCCTAATGGTTCGTAGCATGGTTTTTATTTCTTACGCATTCTTGGCACA CAGTGTAGCTATCCTCCTGACGAGCAACCCGTCTGCGTACCTAAGTGTGGCTCCCCGTGGGTCAGCGTCCTGGTAGCATGGATCCAGTCT GAAAGGTGAGGACAACGTGGAAACTCATGAGCTGAGCCTGCCCGCTGGGACACGTCTCCTTCCCGCGTCACCTTCTGGTTTAGGGAGCCG TCAGGTCCCTAAACGTTCCCTACAACTTTTTCTGAAATTGTGCAGAAAAACAGATCTCATTAAAAGAAAAAAAGAAACAACTTGTAGGAA >98440_98440_2_VPS41-SDK1_VPS41_chr7_38835065_ENST00000310301_SDK1_chr7_4150295_ENST00000404826_length(amino acids)=1344AA_BP=239 MAEAEEQETGSLEESTDESEEEESEEEPKLKYERLSNGVTEILQKDAASCMTVHDKFLALGTHYGKVYLLDVQGNITQKFDVSPVKINQI SLDESGEHMGVCSEDGKVQVFGLYSGEEFHETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGEGNIRSVKWR GHLIAWANNMGVKIFDIISKQRITNVPRDDISLRPDMYPCSLCWKDNVTLIIGWGTSVKVGAIGDEEEWVTLYEEENEPDAQMLEIPNLT PYTHYRFRMKQVNIVGPSPYSPSSRVIQTLQAPPDVAPTSVTVRTASETSLRLRWVPLPDSQYNGNPESVGYRIKYWRSDLQSSAVAQVV SDRLEREFTIEELEEWMEYELQMQAFNAVGAGPWSEVVRGRTRESVPSAAPENVSAEAVSSTQILLTWTSVPEQDQNGLILGYKILFRAK DLDPEPRSHIVRGNHTQSALLAGLRKFVLYELQVLAFTRIGNGVPSTPLILERTKDDAPGPPVRLVFPEVRLTSVRIVWQPPEEPNGIIL GYQIAYRLASSSPHTFTTVEVGATVRQFTATDLAPESAYIFRLSAKTRQGWGEPLEATVITTEKRERPAPPRELLVPQAEVTARSLRLQW VPGSDGASPIRYFTMQVRELPRGEWQTYSSSISHEATACVVDRLRPFTSYKLRLKATNDIGDSDFSSETEAVTTLQDVPGEPPGSVSATP HTTSSVLIQWQPPRDESLNGLLQGYRIYYRELEYEAGSGTEAKTLKNPIALHAELTAQSSFKTVNSSSTSTMCELTHLKKYRRYEVIMTA YNIIGESPASAPVEVFVGEAAPAMAPQNVQVTPLTASQLEVTWDPPPPESQNGNIQGYKIYYWEADSQNETEKMKVLFLPEPVVRLKNLT SHTKYLVSISAFNAAGDGPKSDPQQGRTHQAAPGAPSFLAFSEITSTTLNVSWGEPAAANGILQGYRVVYEPLAPVQGVSKVVTVEVRGN WQRWLKVRDLTKGVTYFFRVQARTITYGPELQANITAGPAEGSPGSPRDVLVTKSASELTLQWTEGHSGDTPTTGYVIEARPSDEGLWDM FVKDIPRSATSYTLSLDKLRQGVTYEFRVVAVNEAGYGEPSNPSTAVSAQVEAPFYEEWWFLLVMALSSLIVILLVVFALVLHGQNKKYK NCSTGKGISTMEESVTLDNGGFAALELSSRHLNVKSTFSKKNGTRSPPRPSPGGLHYSDEDICNKYNGAVLTESVSLKEKSADASESEAT -------------------------------------------------------------- >98440_98440_3_VPS41-SDK1_VPS41_chr7_38835065_ENST00000395969_SDK1_chr7_4150295_ENST00000389531_length(transcript)=4924nt_BP=642nt ATGGCGGAAGCAGAGGAGCAGGAAACTGGGTCCCTTGAAGAATCTACAGATGAGTCTGAGGAAGAAGAGAGCGAAGAGGAACCCAAGCTG AAGTATGAAAGGCTTTCCAATGGGGTAACTGAAATACTTCAGAAGGATGCAGCTAGCTGCATGACAGTCCATGACAAGTTTTTGGCATTG GGCACACATTATGGCAAGGTTTATTTACTTGATGTCCAGGGGAACATCACTCAGAAGTTTGATGTAGTGCAGGTATTTGGACTGTATTCT GGAGAAGAATTTCACGAGACTTTTGACTGTCCCATTAAAATTATTGCTGTGCACCCACATTTCGTGAGATCCAGTTGCAAGCAGTTTGTG ACCGGAGGGAAGAAGCTGCTACTGTTTGAACGGTCTTGGATGAACAGATGGAAGTCTGCTGTTCTGCATGAAGGGGAAGGGAACATAAGG AGTGTGAAGTGGAGAGGCCATCTGATTGCTTGGGCCAATAATATGGGTGTGAAGATTTTTGACATCATCTCAAAGCAAAGAATCACCAAT GTGCCCCGGGATGATATAAGTCTTCGCCCAGACATGTATCCCTGCAGCCTCTGCTGGAAGGACAATGTGACACTGATTATTGGCTGGGGG ACTTCTGTCAAGGTGGGAGCTATCGGCGACGAGGAGGAGTGGGTCACCCTCTATGAAGAGGAGAATGAGCCTGATGCCCAGATGCTGGAG ATCCCAAACCTCACACCCTACACTCACTACAGATTTCGAATGAAGCAAGTGAACATTGTTGGGCCGAGCCCCTACAGTCCGTCTTCCCGG GTCATCCAGACCCTGCAGGCCCCACCCGACGTGGCTCCAACCAGCGTCACGGTCCGTACTGCCAGTGAGACCAGCCTGCGGCTTCGCTGG GTGCCCCTGCCGGATTCTCAGTACAACGGGAACCCCGAGTCCGTGGGCTACAGGATTAAGTACTGGCGCTCAGACCTCCAGTCCTCAGCA GTGGCCCAAGTCGTCAGTGACCGGCTGGAGAGAGAATTCACCATCGAGGAGCTGGAGGAGTGGATGGAATACGAGCTGCAGATGCAGGCC TTCAACGCCGTCGGGGCTGGGCCGTGGAGCGAGGTGGTGCGGGGCCGGACGCGGGAGTCAGTTCCTTCAGCCGCCCCTGAGAACGTGTCA GCCGAGGCTGTCAGCTCGACCCAGATTTTACTGACATGGACATCCGTGCCGGAACAGGACCAGAATGGGCTCATACTGGGCTACAAGATC CTGTTCCGGGCCAAAGACCTGGATCCCGAGCCCAGGAGCCACATCGTGCGAGGGAACCACACGCAGTCGGCCCTGCTGGCAGGCCTGCGC AAGTTCGTGCTCTACGAGCTCCAGGTGCTGGCGTTCACCCGCATCGGGAACGGGGTCCCCAGCACGCCCCTCATCCTGGAGCGCACCAAA GACGATGCCCCAGGCCCACCAGTGAGGCTCGTGTTCCCCGAAGTGAGACTCACCTCCGTGCGGATAGTGTGGCAACCTCCGGAGGAGCCC AACGGCATCATCCTGGGGTACCAGATTGCCTACCGCCTGGCCAGCAGCAGCCCCCACACCTTCACCACCGTGGAGGTCGGCGCCACAGTG AGGCAGTTCACAGCCACCGACCTGGCCCCGGAGTCCGCATACATCTTCAGGCTGTCCGCCAAGACGAGGCAGGGCTGGGGGGAGCCACTG GAGGCCACCGTCATCACCACCGAGAAGAGAGAGCGGCCGGCACCCCCCAGAGAGCTCCTGGTGCCCCAGGCAGAAGTGACCGCACGCAGC CTCCGGCTCCAGTGGGTCCCGGGCAGCGACGGGGCCTCCCCCATCCGGTACTTCACCATGCAGGTGCGAGAGCTGCCTCGGGGTGAGTGG CAGACCTACTCCTCGTCCATCAGCCATGAGGCGACAGCATGCGTCGTTGACAGACTGAGGCCCTTCACCTCCTACAAGCTGCGCCTGAAA GCCACCAACGACATTGGGGACAGTGACTTCAGTTCAGAGACAGAGGCGGTGACCACGCTGCAGGATGTTCCAGGAGAGCCCCCGGGATCT GTCTCAGCGACGCCACACACCACGTCCTCTGTCCTGATACAGTGGCAGCCTCCGAGGGACGAAAGCCTGAATGGCCTTCTTCAGGGATAC AGGATCTACTACAGGGAGCTGGAGTATGAAGCCGGGTCAGGCACTGAGGCCAAGACGCTCAAAAACCCTATAGCTTTACATGCTGAGCTC ACAGATTTAAAGAAGTACCGGCGCTATGAAGTAATAATGACCGCCTATAACATCATCGGCGAGAGCCCAGCCAGCGCGCCCGTGGAGGTC TTTGTCGGCGAGGCTGCCCCGGCCATGGCCCCGCAGAACGTGCAGGTGACCCCACTCACGGCCAGCCAGCTGGAGGTCACGTGGGACCCA CCACCCCCGGAGAGCCAGAATGGGAACATCCAAGGCTACAAGATTTACTACTGGGAGGCAGACAGCCAGAACGAAACGGAGAAAATGAAG GTCCTCTTCCTCCCCGAGCCCGTGGTGAGGCTGAAGAACCTGACCAGCCATACCAAGTACCTGGTCAGCATATCAGCCTTCAACGCCGCC GGAGATGGACCTAAGAGTGACCCCCAGCAGGGGCGCACCCACCAGGCCGCCCCTGGGGCCCCCAGCTTTCTGGCGTTCTCAGAAATAACC TCCACCACGCTCAACGTGTCCTGGGGCGAGCCTGCGGCGGCCAACGGCATCCTGCAGGGCTATCGGGTGGTGTACGAGCCCTTGGCCCCT GTACAAGGGGTGAGCAAGGTGGTGACCGTGGAAGTGAGAGGGAACTGGCAGCGCTGGCTGAAGGTGCGGGACCTCACCAAGGGAGTGACC TATTTCTTCCGTGTCCAAGCGCGGACCATCACCTACGGGCCCGAGCTCCAAGCCAATATCACAGCCGGGCCAGCCGAGGGATCCCCGGGC TCGCCTAGAGATGTCCTGGTCACCAAGTCCGCCTCTGAACTGACGCTGCAGTGGACTGAGGGACACTCTGGCGACACACCTACCACGGGC TATGTGATCGAGGCCCGGCCCTCAGATGAAGGCTTATGGGACATGTTTGTGAAGGACATCCCGCGGAGCGCCACATCCTACACCCTCAGC CTGGATAAGCTCCGGCAAGGAGTGACTTACGAGTTCCGGGTGGTGGCTGTGAATGAGGCGGGCTACGGGGAGCCCAGCAACCCCTCCACG GCTGTGTCAGCTCAAGTGGAAGCCCCATTCTACGAGGAGTGGTGGTTCCTCCTGGTGATGGCTCTGTCCAGCCTGATCGTCATCCTGCTG GTGGTGTTCGCCCTCGTCCTGCACGGGCAGAATAAGAAGTATAAGAACTGCAGCACAGGAAAGGGGATCTCCACCATGGAGGAGTCTGTG ACCCTGGACAACGGAGGATTTGCTGCCCTGGAGCTCAGCAGCCGCCACCTCAATGTCAAGAGCACCTTCTCCAAGAAGAACGGGACCAGG TCCCCACCCCGGCCTAGCCCCGGCGGCCTGCACTACTCAGACGAGGACATCTGCAACAAGTACAACGGCGCCGTGCTGACCGAGAGCGTG AGCCTCAAGGAGAAGTCGGCAGATGCATCAGAATCTGAGGCCACGGACTCTGACTACGAGGACGCGCTGCCCAAGCACTCCTTCGTGAAC CACTACATGAGCGACCCCACCTACTACAACTCATGGAAGCGCAGGGCCCAGGGCCGCGCACCTGCGCCGCACAGGTACGAGGCGGTGGCG GGCTCCGAGGCGGGCGCGCAGCTGCACCCGGTCATCACCACGCAGAGCGCGGGCGGCGTCTACACCCCCGCTGGCCCCGGCGCGCGAACT CCGCTCACCGGCTTCTCCTCCTTCGTGTGAGCAAAGCGCCGCGCCTCCCTCAGGGCGGAACGGAGGCAACTTTCCGGAGTCTATTTTTGT TAAGACAATCAACTCCAATAACTGAGCTGAAGTTTTTGTTTAAAAAGAAAAAAATCTGATAAGTGATGATTTTACCTACTTGTGGACACT AGATTTCAATTAGGAAGGTTTTTTTAAACGGCTTTTTGTAACTTCGCTGCAGGAAGCAGGTTTGTTTCTTTTTCTTTTCTTTTTAAGAGA AGGTGTATTTCACTGGTGCAATGGCTTGGCACCTCCGGGGCCTGGGAGGACCTCAGACCTCCCCAGCCCTGGGTTTCTCCGTCTTCAAGA CCAACTAGGAAGGGTCAAGCGGGGAGAGGGAGTGGAGGGTCAGGTGAGATCTCAGAGCTGCCCCGGCCGGCCCCCGTCTCTTTCTACCTC CTCTTCCAGAGAACCAGCGGCTCACACCCTTCTCAACGCAGGACATCCTCGGCGGCTCCTGGGGTTTGAAGAGCAAACGTTTTTCCCTGG GCTCAGTGCGTTTTGTCCCAACTTCATCTGTTTCTGAAATGTTCTCACTTGGCAGTGTCTAGTCAAGGAGTCGGCTTTCAGGTTCCTGAC GGCCAGGCAGGGATGCTAAGGTGTGGCTCAGCCGTCACTGTCTGTGTCACTGCAGTGGTGCGGTCCTCAGGCTTTTCTGCCTGTCTTTCC CCCTTCCTTCTCACCTGACAGCGAGGGAGAGGGAAGCCTCTTAGGGCTGGAAGCCACCACGCTGGCCCTCTCCTTCCCCGAACACAGCAC ACGGTCAACTCCGCGGGACACGAGGACACGGGACGGCGTCTCCAGAATTGCTTGTTACGTAGGAAGCGTGCATTGTTAACCAGAGTATTT TTAAAATCTTTTTATCTTTTTTTAAACTATGTCACATGAAATGAATGCGTCTTTGCTGTCTCCAGGTGCCTTTTTATTAATTGTTCAGCT >98440_98440_3_VPS41-SDK1_VPS41_chr7_38835065_ENST00000395969_SDK1_chr7_4150295_ENST00000389531_length(amino acids)=1299AA_BP=214 MAEAEEQETGSLEESTDESEEEESEEEPKLKYERLSNGVTEILQKDAASCMTVHDKFLALGTHYGKVYLLDVQGNITQKFDVVQVFGLYS GEEFHETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGEGNIRSVKWRGHLIAWANNMGVKIFDIISKQRITN VPRDDISLRPDMYPCSLCWKDNVTLIIGWGTSVKVGAIGDEEEWVTLYEEENEPDAQMLEIPNLTPYTHYRFRMKQVNIVGPSPYSPSSR VIQTLQAPPDVAPTSVTVRTASETSLRLRWVPLPDSQYNGNPESVGYRIKYWRSDLQSSAVAQVVSDRLEREFTIEELEEWMEYELQMQA FNAVGAGPWSEVVRGRTRESVPSAAPENVSAEAVSSTQILLTWTSVPEQDQNGLILGYKILFRAKDLDPEPRSHIVRGNHTQSALLAGLR KFVLYELQVLAFTRIGNGVPSTPLILERTKDDAPGPPVRLVFPEVRLTSVRIVWQPPEEPNGIILGYQIAYRLASSSPHTFTTVEVGATV RQFTATDLAPESAYIFRLSAKTRQGWGEPLEATVITTEKRERPAPPRELLVPQAEVTARSLRLQWVPGSDGASPIRYFTMQVRELPRGEW QTYSSSISHEATACVVDRLRPFTSYKLRLKATNDIGDSDFSSETEAVTTLQDVPGEPPGSVSATPHTTSSVLIQWQPPRDESLNGLLQGY RIYYRELEYEAGSGTEAKTLKNPIALHAELTDLKKYRRYEVIMTAYNIIGESPASAPVEVFVGEAAPAMAPQNVQVTPLTASQLEVTWDP PPPESQNGNIQGYKIYYWEADSQNETEKMKVLFLPEPVVRLKNLTSHTKYLVSISAFNAAGDGPKSDPQQGRTHQAAPGAPSFLAFSEIT STTLNVSWGEPAAANGILQGYRVVYEPLAPVQGVSKVVTVEVRGNWQRWLKVRDLTKGVTYFFRVQARTITYGPELQANITAGPAEGSPG SPRDVLVTKSASELTLQWTEGHSGDTPTTGYVIEARPSDEGLWDMFVKDIPRSATSYTLSLDKLRQGVTYEFRVVAVNEAGYGEPSNPST AVSAQVEAPFYEEWWFLLVMALSSLIVILLVVFALVLHGQNKKYKNCSTGKGISTMEESVTLDNGGFAALELSSRHLNVKSTFSKKNGTR SPPRPSPGGLHYSDEDICNKYNGAVLTESVSLKEKSADASESEATDSDYEDALPKHSFVNHYMSDPTYYNSWKRRAQGRAPAPHRYEAVA -------------------------------------------------------------- >98440_98440_4_VPS41-SDK1_VPS41_chr7_38835065_ENST00000395969_SDK1_chr7_4150295_ENST00000404826_length(transcript)=7576nt_BP=642nt ATGGCGGAAGCAGAGGAGCAGGAAACTGGGTCCCTTGAAGAATCTACAGATGAGTCTGAGGAAGAAGAGAGCGAAGAGGAACCCAAGCTG AAGTATGAAAGGCTTTCCAATGGGGTAACTGAAATACTTCAGAAGGATGCAGCTAGCTGCATGACAGTCCATGACAAGTTTTTGGCATTG GGCACACATTATGGCAAGGTTTATTTACTTGATGTCCAGGGGAACATCACTCAGAAGTTTGATGTAGTGCAGGTATTTGGACTGTATTCT GGAGAAGAATTTCACGAGACTTTTGACTGTCCCATTAAAATTATTGCTGTGCACCCACATTTCGTGAGATCCAGTTGCAAGCAGTTTGTG ACCGGAGGGAAGAAGCTGCTACTGTTTGAACGGTCTTGGATGAACAGATGGAAGTCTGCTGTTCTGCATGAAGGGGAAGGGAACATAAGG AGTGTGAAGTGGAGAGGCCATCTGATTGCTTGGGCCAATAATATGGGTGTGAAGATTTTTGACATCATCTCAAAGCAAAGAATCACCAAT GTGCCCCGGGATGATATAAGTCTTCGCCCAGACATGTATCCCTGCAGCCTCTGCTGGAAGGACAATGTGACACTGATTATTGGCTGGGGG ACTTCTGTCAAGGTGGGAGCTATCGGCGACGAGGAGGAGTGGGTCACCCTCTATGAAGAGGAGAATGAGCCTGATGCCCAGATGCTGGAG ATCCCAAACCTCACACCCTACACTCACTACAGATTTCGAATGAAGCAAGTGAACATTGTTGGGCCGAGCCCCTACAGTCCGTCTTCCCGG GTCATCCAGACCCTGCAGGCCCCACCCGACGTGGCTCCAACCAGCGTCACGGTCCGTACTGCCAGTGAGACCAGCCTGCGGCTTCGCTGG GTGCCCCTGCCGGATTCTCAGTACAACGGGAACCCCGAGTCCGTGGGCTACAGGATTAAGTACTGGCGCTCAGACCTCCAGTCCTCAGCA GTGGCCCAAGTCGTCAGTGACCGGCTGGAGAGAGAATTCACCATCGAGGAGCTGGAGGAGTGGATGGAATACGAGCTGCAGATGCAGGCC TTCAACGCCGTCGGGGCTGGGCCGTGGAGCGAGGTGGTGCGGGGCCGGACGCGGGAGTCAGTTCCTTCAGCCGCCCCTGAGAACGTGTCA GCCGAGGCTGTCAGCTCGACCCAGATTTTACTGACATGGACATCCGTGCCGGAACAGGACCAGAATGGGCTCATACTGGGCTACAAGATC CTGTTCCGGGCCAAAGACCTGGATCCCGAGCCCAGGAGCCACATCGTGCGAGGGAACCACACGCAGTCGGCCCTGCTGGCAGGCCTGCGC AAGTTCGTGCTCTACGAGCTCCAGGTGCTGGCGTTCACCCGCATCGGGAACGGGGTCCCCAGCACGCCCCTCATCCTGGAGCGCACCAAA GACGATGCCCCAGGCCCACCAGTGAGGCTCGTGTTCCCCGAAGTGAGACTCACCTCCGTGCGGATAGTGTGGCAACCTCCGGAGGAGCCC AACGGCATCATCCTGGGGTACCAGATTGCCTACCGCCTGGCCAGCAGCAGCCCCCACACCTTCACCACCGTGGAGGTCGGCGCCACAGTG AGGCAGTTCACAGCCACCGACCTGGCCCCGGAGTCCGCATACATCTTCAGGCTGTCCGCCAAGACGAGGCAGGGCTGGGGGGAGCCACTG GAGGCCACCGTCATCACCACCGAGAAGAGAGAGCGGCCGGCACCCCCCAGAGAGCTCCTGGTGCCCCAGGCAGAAGTGACCGCACGCAGC CTCCGGCTCCAGTGGGTCCCGGGCAGCGACGGGGCCTCCCCCATCCGGTACTTCACCATGCAGGTGCGAGAGCTGCCTCGGGGTGAGTGG CAGACCTACTCCTCGTCCATCAGCCATGAGGCGACAGCATGCGTCGTTGACAGACTGAGGCCCTTCACCTCCTACAAGCTGCGCCTGAAA GCCACCAACGACATTGGGGACAGTGACTTCAGTTCAGAGACAGAGGCGGTGACCACGCTGCAGGATGTTCCAGGAGAGCCCCCGGGATCT GTCTCAGCGACGCCACACACCACGTCCTCTGTCCTGATACAGTGGCAGCCTCCGAGGGACGAAAGCCTGAATGGCCTTCTTCAGGGATAC AGGATCTACTACAGGGAGCTGGAGTATGAAGCCGGGTCAGGCACTGAGGCCAAGACGCTCAAAAACCCTATAGCTTTACATGCTGAGCTC ACAGCCCAAAGCAGCTTCAAGACGGTGAACAGCAGCTCCACATCGACGATGTGTGAACTAACACATTTAAAGAAGTACCGGCGCTATGAA GTAATAATGACCGCCTATAACATCATCGGCGAGAGCCCAGCCAGCGCGCCCGTGGAGGTCTTTGTCGGCGAGGCTGCCCCGGCCATGGCC CCGCAGAACGTGCAGGTGACCCCACTCACGGCCAGCCAGCTGGAGGTCACGTGGGACCCACCACCCCCGGAGAGCCAGAATGGGAACATC CAAGGCTACAAGATTTACTACTGGGAGGCAGACAGCCAGAACGAAACGGAGAAAATGAAGGTCCTCTTCCTCCCCGAGCCCGTGGTGAGG CTGAAGAACCTGACCAGCCATACCAAGTACCTGGTCAGCATATCAGCCTTCAACGCCGCCGGAGATGGACCTAAGAGTGACCCCCAGCAG GGGCGCACCCACCAGGCCGCCCCTGGGGCCCCCAGCTTTCTGGCGTTCTCAGAAATAACCTCCACCACGCTCAACGTGTCCTGGGGCGAG CCTGCGGCGGCCAACGGCATCCTGCAGGGCTATCGGGTGGTGTACGAGCCCTTGGCCCCTGTACAAGGGGTGAGCAAGGTGGTGACCGTG GAAGTGAGAGGGAACTGGCAGCGCTGGCTGAAGGTGCGGGACCTCACCAAGGGAGTGACCTATTTCTTCCGTGTCCAAGCGCGGACCATC ACCTACGGGCCCGAGCTCCAAGCCAATATCACAGCCGGGCCAGCCGAGGGATCCCCGGGCTCGCCTAGAGATGTCCTGGTCACCAAGTCC GCCTCTGAACTGACGCTGCAGTGGACTGAGGGACACTCTGGCGACACACCTACCACGGGCTATGTGATCGAGGCCCGGCCCTCAGATGAA GGCTTATGGGACATGTTTGTGAAGGACATCCCGCGGAGCGCCACATCCTACACCCTCAGCCTGGATAAGCTCCGGCAAGGAGTGACTTAC GAGTTCCGGGTGGTGGCTGTGAATGAGGCGGGCTACGGGGAGCCCAGCAACCCCTCCACGGCTGTGTCAGCTCAAGTGGAAGCCCCATTC TACGAGGAGTGGTGGTTCCTCCTGGTGATGGCTCTGTCCAGCCTGATCGTCATCCTGCTGGTGGTGTTCGCCCTCGTCCTGCACGGGCAG AATAAGAAGTATAAGAACTGCAGCACAGGAAAGGGGATCTCCACCATGGAGGAGTCTGTGACCCTGGACAACGGAGGATTTGCTGCCCTG GAGCTCAGCAGCCGCCACCTCAATGTCAAGAGCACCTTCTCCAAGAAGAACGGGACCAGGTCCCCACCCCGGCCTAGCCCCGGCGGCCTG CACTACTCAGACGAGGACATCTGCAACAAGTACAACGGCGCCGTGCTGACCGAGAGCGTGAGCCTCAAGGAGAAGTCGGCAGATGCATCA GAATCTGAGGCCACGGACTCTGACTACGAGGACGCGCTGCCCAAGCACTCCTTCGTGAACCACTACATGAGCGACCCCACCTACTACAAC TCATGGAAGCGCAGGGCCCAGGGCCGCGCACCTGCGCCGCACAGGTACGAGGCGGTGGCGGGCTCCGAGGCGGGCGCGCAGCTGCACCCG GTCATCACCACGCAGAGCGCGGGCGGCGTCTACACCCCCGCTGGCCCCGGCGCGCGAACTCCGCTCACCGGCTTCTCCTCCTTCGTGTGA GCAAAGCGCCGCGCCTCCCTCAGGGCGGAACGGAGGCAACTTTCCGGAGTCTATTTTTGTTAAGACAATCAACTCCAATAACTGAGCTGA AGTTTTTGTTTAAAAAGAAAAAAATCTGATAAGTGATGATTTTACCTACTTGTGGACACTAGATTTCAATTAGGAAGGTTTTTTTAAACG GCTTTTTGTAACTTCGCTGCAGGAAGCAGGTTTGTTTCTTTTTCTTTTCTTTTTAAGAGAAGGTGTATTTCACTGGTGCAATGGCTTGGC ACCTCCGGGGCCTGGGAGGACCTCAGACCTCCCCAGCCCTGGGTTTCTCCGTCTTCAAGACCAACTAGGAAGGGTCAAGCGGGGAGAGGG AGTGGAGGGTCAGGTGAGATCTCAGAGCTGCCCCGGCCGGCCCCCGTCTCTTTCTACCTCCTCTTCCAGAGAACCAGCGGCTCACACCCT TCTCAACGCAGGACATCCTCGGCGGCTCCTGGGGTTTGAAGAGCAAACGTTTTTCCCTGGGCTCAGTGCGTTTTGTCCCAACTTCATCTG TTTCTGAAATGTTCTCACTTGGCAGTGTCTAGTCAAGGAGTCGGCTTTCAGGTTCCTGACGGCCAGGCAGGGATGCTAAGGTGTGGCTCA GCCGTCACTGTCTGTGTCACTGCAGTGGTGCGGTCCTCAGGCTTTTCTGCCTGTCTTTCCCCCTTCCTTCTCACCTGACAGCGAGGGAGA GGGAAGCCTCTTAGGGCTGGAAGCCACCACGCTGGCCCTCTCCTTCCCCGAACACAGCACACGGTCAACTCCGCGGGACACGAGGACACG GGACGGCGTCTCCAGAATTGCTTGTTACGTAGGAAGCGTGCATTGTTAACCAGAGTATTTTTAAAATCTTTTTATCTTTTTTTAAACTAT GTCACATGAAATGAATGCGTCTTTGCTGTCTCCAGGTGCCTTTTTATTAATTGTTCAGCTTTGTACATGGGAAAGATGAAAAGCAACAGT GTCTGCAAATAAAGCAAAACAGCTCTGAGAACACACGCTCCCGACTCGCCTCGTGCACACCAGGCCGTCCCCTCCCTCTGTCCTGGCTTC TGCTGGCTGCTCGCAGCAGCCACCGCTTCTCCACCACTGGCGCTGCTGCTGCCCCCTCTCCCAGTCCGAGGCCAGCTTTTAGCCTTAACA GGTTTTTTGGAAATGTTTCTTTTTTTTATTTAAAATTGTCATTGTTTGGTTTAAATTTTTCAGCTAGATGAAAAGAGTATGAACTACTTT GGAAAACTTAACAGCTCAGAGATGGCCATGCCTCCAGCCCCTCACGTCATCTTTGCAACAGACGACTGGGCTGCCATGGTCCACCCCTCA GCCCGGGTCCCGGGTCTGGATGGAACGGGAGCACTGCTGGTGCCCACTGGCGTGTGTGCCCCGGGTCCCTGTAAGTGCCCCCTCACCAGC AGCAGCGTGACACACACAAGACTCAAGACCACCCTGTCAGTGCCCCCCAGTGCACGGCAAACGGGCAGGTGCCGTTCCCCCAGTGACCTG AGGGTAGGGGACAACTGAGCAGTATCTGACCAGTGCCACCCAGGAGCCAGTCTCCTGGCCACATGCAGAAAGTGTGGCCCCTGCTTACCT AGATGTTTTGTGCACCTCCATGGGCAGAGGGTGTGGATATTGCCTGGATTCTGTGCTGTCAGCGTTGCTGAGTATGGCCCCAGGAGACCA AGGAGAGTTTTGTATAGGCTGGAAAACCCCTTTTCAGTCTTTCCAAAATTAGAGGGTATGGCAAGTTTCCTTTTTTCTCTCCTCCCTTCC TTCCCCTCCTTCCTTTCCTTTACCCCTCCTTTCCTTCCTTCCTCCCTTCCTCTCTTCTTTCCTCCCTCCCTCCCTCCTTCCCTCCCTTCC TTCCTCTCTTTCCTCCTTCCTTCCCTCCCTTCTTTCCCTCCCTCCCTTCCTCTCTCCCCTATTCCTTCTTCCTTTTCTCCTCCTTTTTCT GAGTGGAGGGGGAAATATTCTAAACCAAAAATCCTAGATGCTCTGCCCAAAGCCACTTCTGCATGAGAATCGCAACCCACAGTTCCCCGG ATGAGACTCACCACAGTGGACAGTGCCACCTCCTTCCCCTCGGCCCCGGAGAGGGCGAAGTGGGCGGGAAGCCAGGATGTGAGCACTGGA ATTTCTTGGAAGAGAAGCGATAAATGGAGACCATGGCCAGCGCTGCTTTCTGTGCACTCTGATGACTGCTCTCTGCAGCCATGAGGATGT GGCTTTACATGCCAGGGAGAGTGTTGAGACGTCTTAGGTTGAGGATGAGCAGATTCGAGATATGTTTGTTGCTCTCGGGTTTTCGATACA ACATCATGACACTTCTGTTTCAAGCTCATGTTTTCCGTCTCCCCTCCACTCTTAGTAAACCTTGATCTGTACGGAGCGGCCTGTCCGAGG CTACGCCGGCCTCCTGGCTGCTGCTGGACTGTGCTTAGGACAGCGCCCATGCCTCGGAGGGACTCTGTCCCATGAGAACCACCTGTGCAA AGGAACAGAGCTGGATGTTTCCAGGTAGATTTTGGCCTCCCAGAGCAATGCGGCATTTGAGAAGCAACAGTTCCTAACTCCTTATCTTCA GGGAAGGAAAAGAAAATCACAGCCTAGGAAGATGGAGGTTGGATTTTAATCTCGGTTTTAAAAAGAGGACAAACAAAATGTCTCTAAGCC AGGCTAGATGGAATGTGCTCCCGCTCTCTCCTGCCGTGCTGAAAGTCATGCCTTGCGGATGCCTCATGACAGCAGTGGCTGAGTCTCCCC ACCCACCCCCAACGTGGCTCATTTCAGATTGCTTCGGCCCCACCCTGCAAGGATGTGGTCACGGAGTGGCCAGGAGGCTCCGTCTGAGCC ACAGGGATGGGTGTGCAGAGCTCCCTCCTCCTGGGGTGCCAGGGCAGAGATTCCAGGCAGGTGAGCCCAGAGAGAGCTGCCAGGCCACAC CCCCTCGGCCTCCTGCACGGCCACCTTCTGGGTGAATCGGTCCAGCCCAAGCCCCTCTCCCCAGCCTCGCCTTCAGCCTCTCTCCCAGCC TGCTTTTATAAGGCGCACTTCACTCAATGCTGTAGCCAAAAAACGAGGGGCCCCAGGGAGAGGGGACCCAGATGGCCACACACGGAACGC GCCTCCACAGCCCCGGGAGGTGGCTCACTCTGTACAGGTCTTCGGAGGCCGTGTTTGTATCTAACTGTGACTGGGCTGAAGCATGATGTT TGCCTAATGGTTCGTAGCATGGTTTTTATTTCTTACGCATTCTTGGCACACAGTGTAGCTATCCTCCTGACGAGCAACCCGTCTGCGTAC CTAAGTGTGGCTCCCCGTGGGTCAGCGTCCTGGTAGCATGGATCCAGTCTGAAAGGTGAGGACAACGTGGAAACTCATGAGCTGAGCCTG CCCGCTGGGACACGTCTCCTTCCCGCGTCACCTTCTGGTTTAGGGAGCCGTCAGGTCCCTAAACGTTCCCTACAACTTTTTCTGAAATTG TGCAGAAAAACAGATCTCATTAAAAGAAAAAAAGAAACAACTTGTAGGAAGACAGAGAGGTGCTATGGGTACAATTTTTAATAAAAACAT >98440_98440_4_VPS41-SDK1_VPS41_chr7_38835065_ENST00000395969_SDK1_chr7_4150295_ENST00000404826_length(amino acids)=1319AA_BP=214 MAEAEEQETGSLEESTDESEEEESEEEPKLKYERLSNGVTEILQKDAASCMTVHDKFLALGTHYGKVYLLDVQGNITQKFDVVQVFGLYS GEEFHETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGEGNIRSVKWRGHLIAWANNMGVKIFDIISKQRITN VPRDDISLRPDMYPCSLCWKDNVTLIIGWGTSVKVGAIGDEEEWVTLYEEENEPDAQMLEIPNLTPYTHYRFRMKQVNIVGPSPYSPSSR VIQTLQAPPDVAPTSVTVRTASETSLRLRWVPLPDSQYNGNPESVGYRIKYWRSDLQSSAVAQVVSDRLEREFTIEELEEWMEYELQMQA FNAVGAGPWSEVVRGRTRESVPSAAPENVSAEAVSSTQILLTWTSVPEQDQNGLILGYKILFRAKDLDPEPRSHIVRGNHTQSALLAGLR KFVLYELQVLAFTRIGNGVPSTPLILERTKDDAPGPPVRLVFPEVRLTSVRIVWQPPEEPNGIILGYQIAYRLASSSPHTFTTVEVGATV RQFTATDLAPESAYIFRLSAKTRQGWGEPLEATVITTEKRERPAPPRELLVPQAEVTARSLRLQWVPGSDGASPIRYFTMQVRELPRGEW QTYSSSISHEATACVVDRLRPFTSYKLRLKATNDIGDSDFSSETEAVTTLQDVPGEPPGSVSATPHTTSSVLIQWQPPRDESLNGLLQGY RIYYRELEYEAGSGTEAKTLKNPIALHAELTAQSSFKTVNSSSTSTMCELTHLKKYRRYEVIMTAYNIIGESPASAPVEVFVGEAAPAMA PQNVQVTPLTASQLEVTWDPPPPESQNGNIQGYKIYYWEADSQNETEKMKVLFLPEPVVRLKNLTSHTKYLVSISAFNAAGDGPKSDPQQ GRTHQAAPGAPSFLAFSEITSTTLNVSWGEPAAANGILQGYRVVYEPLAPVQGVSKVVTVEVRGNWQRWLKVRDLTKGVTYFFRVQARTI TYGPELQANITAGPAEGSPGSPRDVLVTKSASELTLQWTEGHSGDTPTTGYVIEARPSDEGLWDMFVKDIPRSATSYTLSLDKLRQGVTY EFRVVAVNEAGYGEPSNPSTAVSAQVEAPFYEEWWFLLVMALSSLIVILLVVFALVLHGQNKKYKNCSTGKGISTMEESVTLDNGGFAAL ELSSRHLNVKSTFSKKNGTRSPPRPSPGGLHYSDEDICNKYNGAVLTESVSLKEKSADASESEATDSDYEDALPKHSFVNHYMSDPTYYN -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for VPS41-SDK1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Hgene | VPS41 | chr7:38835065 | chr7:4150295 | ENST00000310301 | - | 9 | 29 | 1_540 | 239.0 | 855.0 | ARL8B |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for VPS41-SDK1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for VPS41-SDK1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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