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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:VPS53-LRP1B (FusionGDB2 ID:98483) |
Fusion Gene Summary for VPS53-LRP1B |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: VPS53-LRP1B | Fusion gene ID: 98483 | Hgene | Tgene | Gene symbol | VPS53 | LRP1B | Gene ID | 55275 | 53353 |
| Gene name | VPS53 subunit of GARP complex | LDL receptor related protein 1B | |
| Synonyms | HCCS1|PCH2E|hVps53L|pp13624 | LRP-1B|LRP-DIT|LRPDIT | |
| Cytomap | 17p13.3 | 2q22.1-q22.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | vacuolar protein sorting-associated protein 53 homologVPS53, GARP complex subunit | low-density lipoprotein receptor-related protein 1BLRP-deleted in tumorslow density lipoprotein receptor related protein-deleted in tumorlow density lipoprotein receptor-related protein 1Blow density lipoprotein-related protein 1B (deleted in tumors) | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | . | Q9NZR2 | |
| Ensembl transtripts involved in fusion gene | ENST00000291074, ENST00000401468, ENST00000437048, ENST00000446250, ENST00000571805, ENST00000576149, ENST00000574029, | ENST00000486364, ENST00000389484, | |
| Fusion gene scores | * DoF score | 18 X 15 X 14=3780 | 12 X 13 X 5=780 |
| # samples | 24 | 13 | |
| ** MAII score | log2(24/3780*10)=-3.97727992349992 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(13/780*10)=-2.58496250072116 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: VPS53 [Title/Abstract] AND LRP1B [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | VPS53(463666)-LRP1B(142012210), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | VPS53-LRP1B seems lost the major protein functional domain in Hgene partner, which is a tumor suppressor due to the frame-shifted ORF. VPS53-LRP1B seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF. VPS53-LRP1B seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF. VPS53-LRP1B seems lost the major protein functional domain in Tgene partner, which is a tumor suppressor due to the frame-shifted ORF. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene breakpoints across VPS53 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across LRP1B (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | UCEC | TCGA-AJ-A3NF-01A | VPS53 | chr17 | 463666 | - | LRP1B | chr2 | 142012210 | - |
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Fusion Gene ORF analysis for VPS53-LRP1B |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000291074 | ENST00000486364 | VPS53 | chr17 | 463666 | - | LRP1B | chr2 | 142012210 | - |
| 5CDS-intron | ENST00000401468 | ENST00000486364 | VPS53 | chr17 | 463666 | - | LRP1B | chr2 | 142012210 | - |
| 5CDS-intron | ENST00000437048 | ENST00000486364 | VPS53 | chr17 | 463666 | - | LRP1B | chr2 | 142012210 | - |
| 5CDS-intron | ENST00000446250 | ENST00000486364 | VPS53 | chr17 | 463666 | - | LRP1B | chr2 | 142012210 | - |
| 5CDS-intron | ENST00000571805 | ENST00000486364 | VPS53 | chr17 | 463666 | - | LRP1B | chr2 | 142012210 | - |
| 5UTR-3CDS | ENST00000576149 | ENST00000389484 | VPS53 | chr17 | 463666 | - | LRP1B | chr2 | 142012210 | - |
| 5UTR-intron | ENST00000576149 | ENST00000486364 | VPS53 | chr17 | 463666 | - | LRP1B | chr2 | 142012210 | - |
| Frame-shift | ENST00000291074 | ENST00000389484 | VPS53 | chr17 | 463666 | - | LRP1B | chr2 | 142012210 | - |
| Frame-shift | ENST00000401468 | ENST00000389484 | VPS53 | chr17 | 463666 | - | LRP1B | chr2 | 142012210 | - |
| Frame-shift | ENST00000437048 | ENST00000389484 | VPS53 | chr17 | 463666 | - | LRP1B | chr2 | 142012210 | - |
| Frame-shift | ENST00000571805 | ENST00000389484 | VPS53 | chr17 | 463666 | - | LRP1B | chr2 | 142012210 | - |
| In-frame | ENST00000446250 | ENST00000389484 | VPS53 | chr17 | 463666 | - | LRP1B | chr2 | 142012210 | - |
| intron-3CDS | ENST00000574029 | ENST00000389484 | VPS53 | chr17 | 463666 | - | LRP1B | chr2 | 142012210 | - |
| intron-intron | ENST00000574029 | ENST00000486364 | VPS53 | chr17 | 463666 | - | LRP1B | chr2 | 142012210 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000446250 | VPS53 | chr17 | 463666 | - | ENST00000389484 | LRP1B | chr2 | 142012210 | - | 17169 | 1949 | 1927 | 15405 | 4492 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000446250 | ENST00000389484 | VPS53 | chr17 | 463666 | - | LRP1B | chr2 | 142012210 | - | 0.00146098 | 0.998539 |
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Fusion Genomic Features for VPS53-LRP1B |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for VPS53-LRP1B |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:463666/chr2:142012210) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | LRP1B |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: Potential cell surface proteins that bind and internalize ligands in the process of receptor-mediated endocytosis. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | VPS53 | chr17:463666 | chr2:142012210 | ENST00000291074 | - | 14 | 18 | 97_138 | 539 | 671.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | VPS53 | chr17:463666 | chr2:142012210 | ENST00000437048 | - | 15 | 22 | 97_138 | 568 | 833.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | VPS53 | chr17:463666 | chr2:142012210 | ENST00000571805 | - | 15 | 19 | 97_138 | 568 | 700.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 1005_1043 | 114 | 4600.0 | Domain | LDL-receptor class A 7 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 1052_1089 | 114 | 4600.0 | Domain | LDL-receptor class A 8 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 1094_1132 | 114 | 4600.0 | Domain | LDL-receptor class A 9 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 1135_1174 | 114 | 4600.0 | Domain | LDL-receptor class A 10 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 116_154 | 114 | 4600.0 | Domain | EGF-like 1 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 1174_1213 | 114 | 4600.0 | Domain | EGF-like 5 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 1214_1253 | 114 | 4600.0 | Domain | EGF-like 6 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 1527_1570 | 114 | 4600.0 | Domain | EGF-like 7 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 155_194 | 114 | 4600.0 | Domain | EGF-like 2%3B calcium-binding | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 1834_1875 | 114 | 4600.0 | Domain | EGF-like 8 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 2143_2183 | 114 | 4600.0 | Domain | EGF-like 9 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 2464_2504 | 114 | 4600.0 | Domain | EGF-like 10 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 2509_2548 | 114 | 4600.0 | Domain | LDL-receptor class A 11 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 2551_2587 | 114 | 4600.0 | Domain | LDL-receptor class A 12 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 2590_2626 | 114 | 4600.0 | Domain | LDL-receptor class A 13 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 2629_2675 | 114 | 4600.0 | Domain | LDL-receptor class A 14 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 2681_2717 | 114 | 4600.0 | Domain | LDL-receptor class A 15 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 2719_2757 | 114 | 4600.0 | Domain | LDL-receptor class A 16 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 2760_2800 | 114 | 4600.0 | Domain | LDL-receptor class A 17 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 2804_2841 | 114 | 4600.0 | Domain | LDL-receptor class A 18 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 2844_2885 | 114 | 4600.0 | Domain | LDL-receptor class A 19 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 2890_2926 | 114 | 4600.0 | Domain | LDL-receptor class A 20 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 2927_2967 | 114 | 4600.0 | Domain | EGF-like 11 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 2968_3008 | 114 | 4600.0 | Domain | EGF-like 12%3B calcium-binding | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 3273_3314 | 114 | 4600.0 | Domain | EGF-like 13 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 3316_3353 | 114 | 4600.0 | Domain | LDL-receptor class A 21 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 3356_3392 | 114 | 4600.0 | Domain | LDL-receptor class A 22 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 3395_3432 | 114 | 4600.0 | Domain | LDL-receptor class A 23 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 3435_3472 | 114 | 4600.0 | Domain | LDL-receptor class A 24 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 3475_3511 | 114 | 4600.0 | Domain | LDL-receptor class A 25 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 3514_3550 | 114 | 4600.0 | Domain | LDL-receptor class A 26 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 3552_3588 | 114 | 4600.0 | Domain | LDL-receptor class A 27 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 3593_3629 | 114 | 4600.0 | Domain | LDL-receptor class A 28 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 3631_3668 | 114 | 4600.0 | Domain | LDL-receptor class A 29 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 3673_3711 | 114 | 4600.0 | Domain | LDL-receptor class A 30 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 3714_3752 | 114 | 4600.0 | Domain | LDL-receptor class A 31 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 3761_3797 | 114 | 4600.0 | Domain | LDL-receptor class A 32 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 3801_3843 | 114 | 4600.0 | Domain | EGF-like 14 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 3844_3881 | 114 | 4600.0 | Domain | EGF-like 15 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 4171_4208 | 114 | 4600.0 | Domain | EGF-like 16 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 4213_4249 | 114 | 4600.0 | Domain | EGF-like 17 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 4249_4285 | 114 | 4600.0 | Domain | EGF-like 18 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 4285_4321 | 114 | 4600.0 | Domain | EGF-like 19 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 4321_4357 | 114 | 4600.0 | Domain | EGF-like 20 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 4357_4392 | 114 | 4600.0 | Domain | EGF-like 21 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 4390_4427 | 114 | 4600.0 | Domain | EGF-like 22 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 471_517 | 114 | 4600.0 | Domain | EGF-like 3 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 794_834 | 114 | 4600.0 | Domain | EGF-like 4 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 844_882 | 114 | 4600.0 | Domain | LDL-receptor class A 3 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 885_923 | 114 | 4600.0 | Domain | LDL-receptor class A 4 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 926_963 | 114 | 4600.0 | Domain | LDL-receptor class A 5 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 966_1003 | 114 | 4600.0 | Domain | LDL-receptor class A 6 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 4492_4495 | 114 | 4600.0 | Motif | Endocytosis signal | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 4559_4562 | 114 | 4600.0 | Motif | Endocytosis signal | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 1300_1346 | 114 | 4600.0 | Repeat | Note=LDL-receptor class B 8 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 1347_1389 | 114 | 4600.0 | Repeat | Note=LDL-receptor class B 9 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 1390_1436 | 114 | 4600.0 | Repeat | Note=LDL-receptor class B 10 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 1437_1480 | 114 | 4600.0 | Repeat | Note=LDL-receptor class B 11 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 1481_1522 | 114 | 4600.0 | Repeat | Note=LDL-receptor class B 12 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 1618_1660 | 114 | 4600.0 | Repeat | Note=LDL-receptor class B 13 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 1661_1704 | 114 | 4600.0 | Repeat | Note=LDL-receptor class B 14 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 1705_1744 | 114 | 4600.0 | Repeat | Note=LDL-receptor class B 15 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 1745_1787 | 114 | 4600.0 | Repeat | Note=LDL-receptor class B 16 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 1922_1964 | 114 | 4600.0 | Repeat | Note=LDL-receptor class B 17 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 1965_2007 | 114 | 4600.0 | Repeat | Note=LDL-receptor class B 28 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 2008_2051 | 114 | 4600.0 | Repeat | Note=LDL-receptor class B 19 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 2052_2095 | 114 | 4600.0 | Repeat | Note=LDL-receptor class B 20 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 2239_2280 | 114 | 4600.0 | Repeat | Note=LDL-receptor class B 21 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 2281_2329 | 114 | 4600.0 | Repeat | Note=LDL-receptor class B 22 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 2330_2374 | 114 | 4600.0 | Repeat | Note=LDL-receptor class B 23 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 2375_2416 | 114 | 4600.0 | Repeat | Note=LDL-receptor class B 24 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 2417_2459 | 114 | 4600.0 | Repeat | Note=LDL-receptor class B 25 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 295_337 | 114 | 4600.0 | Repeat | Note=LDL-receptor class B 1 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 3055_3098 | 114 | 4600.0 | Repeat | Note=LDL-receptor class B 26 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 3099_3141 | 114 | 4600.0 | Repeat | Note=LDL-receptor class B 27 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 3142_3185 | 114 | 4600.0 | Repeat | Note=LDL-receptor class B 28 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 3186_3224 | 114 | 4600.0 | Repeat | Note=LDL-receptor class B 29 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 3225_3268 | 114 | 4600.0 | Repeat | Note=LDL-receptor class B 30 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 338_381 | 114 | 4600.0 | Repeat | Note=LDL-receptor class B 2 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 382_425 | 114 | 4600.0 | Repeat | Note=LDL-receptor class B 3 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 3933_3980 | 114 | 4600.0 | Repeat | Note=LDL-receptor class B 31 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 3981_4038 | 114 | 4600.0 | Repeat | Note=LDL-receptor class B 32 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 4039_4082 | 114 | 4600.0 | Repeat | Note=LDL-receptor class B 33 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 4083_4127 | 114 | 4600.0 | Repeat | Note=LDL-receptor class B 34 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 568_610 | 114 | 4600.0 | Repeat | Note=LDL-receptor class B 4 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 611_656 | 114 | 4600.0 | Repeat | Note=LDL-receptor class B 5 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 657_706 | 114 | 4600.0 | Repeat | Note=LDL-receptor class B 6 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 707_750 | 114 | 4600.0 | Repeat | Note=LDL-receptor class B 7 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 4468_4599 | 114 | 4600.0 | Topological domain | Cytoplasmic | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 4445_4467 | 114 | 4600.0 | Transmembrane | Helical |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 31_70 | 114 | 4600.0 | Domain | LDL-receptor class A 1 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 76_114 | 114 | 4600.0 | Domain | LDL-receptor class A 2 | |
| Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 25_4444 | 114 | 4600.0 | Topological domain | Extracellular |
Top |
Fusion Gene Sequence for VPS53-LRP1B |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >98483_98483_1_VPS53-LRP1B_VPS53_chr17_463666_ENST00000446250_LRP1B_chr2_142012210_ENST00000389484_length(transcript)=17169nt_BP=1949nt GAAGTGCCGGAGCGGCTGACAGAGCGGCTGACGGAGCCGGGCTCACCAGGTCGCTGCCGCGAGGGAGTTGCTGTGCTGGGGCCTGGGTGG CGGCTGGAGGCCTGAGTTGGGCTCGCGGCGGGGGTCGGCAGGGGGCCGGGTGGCGGAATGATGGAGGAGGAGGAACTGGAGTTCGTGGAG GAGCTGGAAGCCGTGCTGCAGCTCACGCCCGAGGTGCAGCTGGCCATCGAGCAGGTGTTTCCAAGCCAGGACCCTCTAGATCGAGCAGAT TTCAATGCTGTTGAGTATATCAATACCCTGTTCCCAACCGAGCAATCTCTGGCGAACATAGACGAAGTCGTGAACAAAATTAGGCTGAAA ATAAGGAGACTGGATGACAATATTCGAACTGTTGTAAGAGGTCAGACGAACGTGGGGCAGGATGGACGGCAAGCGCTTGAAGAGGCTCAG AAAGCTATCCAACAACTCTTTGGCAAAATCAAAGATATCAAAGACAAAGCTGAAAAATCAGAGCAAATGGTGAAAGAAATCACCCGTGAT ATTAAGCAATTAGATCACGCCAAACGCCACCTGACCACCTCAATCACCACACTGAACCACCTGCACATGCTGGCAGGAGGTGTCGACTCC CTCGAAGCCATGACCAGGCGAAGACAATACGGAGAAGTTGCTAATCTCCTTCAGGGTGTGATGAATGTCCTGGAGCACTTCCACAAGTAT ATGGGGATTCCGCAGATCCGGCAGCTTTCCGAAAGGAAACCCAAAACACTGCAGCTGCATGGATTGAACTGGACGTGATGTGAAATGAAA TAAGCCAGACACGGGAAGACAGATTCCTCATGTTCTCACTCATAGTGAAGGCTGCACAGACTGAGTTAGGACAGCAAATCCTGGCAGATT TTGAAGAAGCGTTTCCTTCCCAGGGCACCAAGAGACCAGGAGGACCCAGCAATGTTCTACGAGATGCATGTCTGGTTGCTAATATTCTAG ATCCCAGGATCAAACAGGAAATCATCAAAAAGTTTATTAAACAGCATCTGTCAGAGTATCTGGTACTTTTTCAAGAAAACCAAGATGTTG CCTGGCTGGACAAAATCGACAGACGCTATGCCTGGATAAAACGCCAGCTTGTGGACTATGAGGAGAAATACGGCCGCATGTTTCCACGTG AGTGGTGCATGGCTGAGAGGATTGCGGTGGAATTTTGCCATGTGACAAGGGCAGAACTTGCCAAGATTATGCGTACCAGAGCGAAGGAAA TTGAAGTGAAATTGCTTCTTTTTGCTATTCAAAGAACAACTAACTTTGAGGGGTTTCTTGCAAAACGCTTCTCCGGCTGCACCCTGACCG ATGGGACCCTGAAAAAGCTTGAGTCTCCACCCCCATCTACCAATCCCTTCCTGGAAGATGAGCCAACACCAGAGATGGAGGAACTGGCAA CGGAGAAAGGAGATTTAGATCAACCAAAGAAGCCTAAAGCCCCAGACAATCCATTTCATGGCATTGTTTCCAAGTGTTTTGAGCCTCATC TCTACGTGTATATCGAATCCCAAGACAAGAACCTCGGAGAGCTGATAGATCGGTTTGTGGCTGATTTCAAAGCCCAGGGGCCACCTAAGC CCAACACTGATGAAGGGGGTGCCGTGCTCCCCAGCTGCGCCGACCTCTTTGTCTACTACAAGAAGTGCATGGTGCAATGCTCTCAGCTCA GTACTGGGGAGCCCATGATCGCCCTGACCACCATTTTCCAGAAGTACCTCCGAGAATACGCCTGGAAAATCCTCTCTGGCAACCTGCCCA AAACCACAACCAGCAGTGGAGGACTGACTATCAGCAGCCTCCTCAAGGAAAAGGAGGGCTCAGAAGTAGCCAAGTTCACTCTGGAGGAGC TCTGCCTCATCTGTAACATCCTGAGCACGGCAGAGTACTGTCTGGCCACCACCCAGCAGAACTGTTATCCAATTGCCAACAGCTGAATTG TCAGTATAAATGTACAATGGTCAGAAATAGTACAAGATGTTACTGTGAGGATGGATTCGAAATAACAGAAGATGGGAGAAGCTGTAAAGA TCAAGATGAATGTGCTGTTTATGGTACATGCAGCCAGACCTGCAGAAACACACATGGATCCTACACTTGCAGTTGTGTGGAAGGCTACCT AATGCAGCCAGACAACAGATCTTGCAAGGCTAAAATTGAACCTACAGATAGACCACCTATACTATTAATTGCAAATTTTGAAACAATTGA GGTTTTCTATCTTAATGGAAGTAAAATGGCAACTCTAAGCTCAGTCAATGGAAATGAAATTCATACTCTGGATTTTATTTATAATGAAGA TATGATTTGTTGGATTGAATCAAGAGAATCTTCAAATCAACTCAAATGTATCCAGATAACAAAAGCAGGAGGATTAACAGATGAATGGAC AATCAATATTCTTCAATCCTTCCACAATGTGCAACAAATGGCGATTGACTGGCTCACTCGAAATCTCTATTTTGTGGACCATGTCGGTGA CCGGATCTTTGTTTGTAATTCCAACGGTTCTGTATGTGTCACCCTGATTGATCTGGAGCTTCACAATCCTAAAGCAATAGCAGTAGATCC AATAGCAGGAAAACTTTTCTTTACTGACTACGGGAATGTCGCCAAAGTGGAGAGATGTGACATGGATGGGATGAACCGAACAAGGATAAT TGATTCAAAGACAGAGCAGCCAGCTGCACTGGCACTAGACCTAGTCAACAAATTGGTTTACTGGGTAGATCTTTACTTGGACTATGTGGG AGTAGTGGACTATCAAGGAAAAAATAGACACACTGTCATTCAAGGCAGACAAGTTAGACATCTTTATGGTATAACTGTGTTTGAAGATTA TTTGTATGCAACCAATTCTGATAACTACAATATCGTAAGGATAAACCGATTTAATGGGACTGATATTCACTCATTAATTAAAATTGAGAA TGCTTGGGGAATCCGAATTTATCAAAAAAGAACTCAACCAACAGTCAGAAGCCATGCATGTGAAGTCGATCCATATGGAATGCCAGGGGG CTGTTCACACATCTGTCTACTCAGCAGCAGTTACAAAACTCGGACTTGTCGCTGCAGGACTGGCTTCAACTTGGGAAGTGATGGCAGGTC ATGCAAAAGACCAAAGAATGAGTTGTTCCTCTTTTATGGGAAAGGACGCCCAGGAATTGTTAGAGGAATGGACTTGAATACCAAGATAGC TGATGAATACATGATCCCCATAGAAAATCTGGTAAACCCTCGTGCTTTAGACTTTCACGCAGAAACCAATTACATCTACTTTGCTGACAC CACCAGTTTCCTAATTGGCCGGCAGAAGATAGATGGCACAGAGAGAGAAACCATCCTGAAAGATGATCTGGATAATGTAGAGGGCATTGC TGTGGACTGGATTGGAAATAATCTTTACTGGACCAATGATGGCCATAGGAAAACCATTAATGTGGCCAGGCTGGAAAAAGCTTCTCAGAG TCGGAAGACTCTTTTAGAGGGTGAAATGTCTCATCCCAGAGGAATTGTGGTGGATCCAGTTAATGGTTGGATGTATTGGACAGACTGGGA GGAAGATGAAATAGATGACAGCGTGGGAAGGATTGAGAAGGCCTGGATGGATGGATTCAATCGGCAGATTTTTGTGACTTCAAAGATGCT GTGGCCAAACGGTTTAACTCTGGACTTTCACACCAACACATTATACTGGTGTGATGCCTATTACGATCATATTGAAAAAGTATTTTTGAA TGGGACTCACAGGAAGATTGTTTACAGTGGGAGAGAGTTGAACCACCCTTTCGGACTGTCGCATCATGGAAATTATGTGTTCTGGACTGA TTATATGAATGGTTCCATTTTTCAACTAGATTTGATAACAAGTGAGGTGACATTGCTGAGGCATGAAAGACCACCCCTATTTGGGCTTCA GATTTATGATCCACGAAAGCAACAAGGTGACAATATGTGCCGAGTAAATAATGGGGGCTGTAGTACACTTTGCTTGGCTATCCCAGGAGG CCGGGTGTGTGCTTGTGCCGATAATCAACTTTTGGATGAAAATGGGACAACTTGCACATTTAATCCTGGAGAAGCACTACCTCACATATG TAAAGCTGGAGAGTTTCGCTGCAAAAACAGACACTGTATCCAAGCTCGGTGGAAATGTGATGGCGACGATGACTGCCTAGACGGAAGCGA TGAGGATTCAGTAAACTGCTTCAATCATAGCTGTCCTGATGATCAGTTTAAATGCCAGAATAATCGCTGCATCCCCAAGAGATGGCTTTG TGATGGAGCTAATGACTGTGGGAGCAATGAAGATGAATCCAATCAAACTTGCACAGCCAGAACATGCCAGGTAGACCAGTTTTCTTGCGG AAATGGGCGTTGCATTCCCAGAGCATGGCTGTGTGACAGGGAAGACGACTGTGGTGACCAGACAGATGAAATGGCATCTTGTGAATTCCC AACTTGTGAGCCACTAACCCAATTCGTATGCAAAAGTGGAAGATGCATTAGCAGCAAATGGCACTGCGACTCTGATGACGACTGTGGGGA CGGGAGTGATGAGGTGGGCTGTGTTCACTCTTGCTTTGATAATCAGTTCAGATGTTCCAGTGGCAGATGCATCCCAGGCCACTGGGCCTG TGATGGTGACAATGACTGTGGGGACTTCAGTGATGAAGCCCAGATCAATTGTACTAAAGAAGAGATTCATTCTCCTGCTGGTTGTAACGG AAATGAATTTCAGTGCCACCCTGATGGTAATTGCGTTCCTGATTTGTGGCGCTGTGATGGAGAAAAAGACTGTGAAGATGGTAGTGATGA AAAAGGTTGCAATGGTACCATACGATTGTGTGACCACAAAACCAAGTTTTCCTGTTGGAGTACAGGGAGATGCATCAACAAAGCATGGGT GTGTGATGGAGATATTGATTGCGAAGATCAGTCAGATGAAGATGACTGTGACAGTTTCTTGTGTGGACCACCCAAGCATCCTTGTGCTAA TGACACCTCAGTCTGCCTGCAGCCAGAGAAACTCTGCAATGGGAAAAAGGATTGTCCTGATGGCTCTGATGAAGGCTATCTCTGTGATGA GTGTTCGCTGAACAATGGAGGCTGTAGCAACCACTGTTCTGTTGTTCCTGGAAGAGGAATTGTCTGTTCCTGCCCTGAAGGACTTCAACT CAACAAAGACAATAAAACATGTGAAATTGTGGATTATTGTAGCAATCATCTAAAGTGCAGCCAAGTATGTGAGCAGCACAAGCACACAGT CAAGTGCTCATGTTATGAAGGTTGGAAGCTGGATGTAGACGGTGAAAGTTGTACAAGTGTTGATCCTTTTGAAGCATTCATCATCTTTTC TATTCGTCATGAGATCAGAAGGATTGATCTTCACAAAAGAGACTATAGTCTACTTGTTCCTGGATTGAGAAACACAATAGCACTTGATTT TCACTTCAATCAAAGTTTACTTTATTGGACAGATGTTGTAGAAGACAGAATATACCGGGGAAAGCTTTCTGAAAGTGGAGGTGTCAGTGC CATTGAAGTGGTTGTGGAGCATGGCCTGGCTACTCCAGAAGGCCTGACAGTCGACTGGATAGCAGGAAACATATACTGGATAGACAGCAA TCTGGACCAAATCGAAGTGGCCAAACTAGATGGCTCCCTAAGAACTACACTAATAGCAGGAGCCATGGAACACCCCAGGGCCATTGCTTT GGACCCAAGATATGGAATTCTTTTCTGGACAGACTGGGATGCAAATTTTCCTCGCATTGAATCTGCCTCTATGAGTGGTGCTGGGAGAAA AACCATCTATAAAGACATGAAAACTGGGGCTTGGCCTAATGGACTAACTGTGGACCACTTTGAGAAAAGGATAGTGTGGACAGACGCCAG GTCAGATGCTATTTATTCAGCCCTCTATGATGGAACAAACATGATAGAAATCATCCGAGGTCATGAATACCTTTCCCATCCCTTTGCTGT GTCTCTATATGGGAGTGAAGTCTACTGGACAGACTGGAGGACCAACACATTGTCCAAAGCCAATAAGTGGACAGGGCAGAATGTCAGTGT GATTCAGAAAACCAGTGCACAGCCATTTGACCTTCAGATATACCATCCCAGTCGCCAGCCACAGGCTCCCAATCCTTGTGCAGCTAATGA TGGCAAAGGCCCCTGCTCTCACATGTGTCTAATCAATCACAATAGGAGTGCTGCCTGTGCGTGCCCCCACTTGATGAAGCTTTCTTCAGA CAAGAAGACCTGCTATGAAATGAAAAAATTTCTTCTTTATGCAAGACGTTCTGAAATCAGAGGAGTGGATATTGACAATCCATACTTTAA CTTCATCACGGCATTTACAGTCCCTGATATTGATGACGTTACTGTGATAGACTTCGATGCATCTGAGGAACGTTTATACTGGACAGATAT TAAAACACAAACCATTAAACGAGCTTTTATTAACGGAACTGGGTTAGAAACTGTTATTTCAAGAGATATTCAGAGTATCAGAGGGCTAGC AGTGGATTGGGTGTCACGTAATTTATACTGGATTAGCTCAGAATTTGATGAAACGCAAATTAATGTGGCAAGGCTAGATGGCTCTTTGAA AACCTCAATTATCCATGGAATCGATAAGCCACAGTGTCTTGCAGCTCACCCAGTCAGGGGAAAACTCTACTGGACCGATGGAAACACAAT TAACATGGCAAATATGGATGGCAGTAATAGCAAGATTCTGTTTCAGAATCAGAAGGAGCCAGTTGGTCTATCGATAGACTATGTGGAAAA CAAGCTTTATTGGATCAGTTCAGGGAATGGAACCATAAATAGATGCAACCTGGATGGTGGTAATTTAGAAGTAATCGAGTCAATGAAAGA AGAATTAACAAAAGCTACAGCCCTAACCATCATGGATAAGAAACTGTGGTGGGCAGACCAAAACTTAGCCCAGCTAGGAACCTGCAGCAA AAGAGACGGAAGAAACCCCACCATCCTACGGAATAAGACTTCTGGGGTAGTTCATATGAAAGTCTATGATAAAGAAGCACAGCAAGGCAG CAATTCCTGCCAACTAAACAATGGTGGATGCTCTCAACTTTGTTTACCAACATCTGAAACTACAAGGACTTGTATGTGTACAGTGGGATA TTATCTCCAAAAGAACCGTATGTCATGTCAAGGTATAGAATCATTTCTTATGTACTCTGTTCATGAAGGAATCAGGGGAATACCTCTTGA ACCAAGTGACAAAATGGATGCTTTGATGCCTATATCAGGAACTTCATTTGCCGTGGGAATAGATTTCCATGCAGAAAATGATACCATCTA CTGGACAGACATGGGCTTCAATAAAATTAGCAGAGCTAAAAGAGATCAGACTTGGAAAGAAGATATCATTACCAATGGCTTGGGAAGAGT GGAAGGGATAGCTGTTGACTGGATTGCTGGTAACATATATTGGACAGATCATGGTTTCAACTTAATTGAAGTTGCAAGACTCAATGGTTC TTTCCGTTATGTAATTATTTCCCAAGGCCTGGATCAACCAAGATCTATAGCTGTGCACCCAGAGAAAGGCCTCTTGTTCTGGACTGAATG GGGACAAATGCCCTGTATTGGAAAGGCTCGCTTGGATGGCTCAGAGAAGGTTGTCCTTGTAAGCATGGGAATAGCATGGCCGAATGGCAT CTCCATCGACTATGAGGAAAATAAATTGTACTGGTGTGATGCTCGCACAGACAAGATAGAGAGAATCGACCTTGAGACTGGAGGGAATCG CGAGATGGTGCTGTCAGGAAGCAATGTGGATATGTTTTCAGTTGCAGTCTTTGGGGCTTACATCTACTGGTCTGACAGAGCACATGCAAA CGGGTCTGTCAGAAGGGGCCACAAGAATGATGCCACAGAAACGATAACCATGAGAACCGGCCTTGGAGTCAACCTGAAGGAGGTTAAAAT ATTTAACCGAGTAAGAGAGAAAGGGACCAATGTTTGTGCCAGGGACAATGGTGGCTGTAAGCAACTCTGTCTTTATCGAGGAAATTCCCG GAGAACTTGTGCTTGTGCCCATGGATATTTGGCAGAAGATGGAGTTACTTGCCTGAGGCATGAAGGCTATTTACTGTATTCAGGAAGAAC AATATTAAAAAGTATACATCTTTCTGATGAAACCAATTTAAATTCCCCAATAAGGCCATATGAGAATCCACGTTATTTCAAGAATGTCAT AGCCTTGGCTTTTGACTATAATCAAAGAAGAAAAGGTACCAACCGAATCTTTTACAGTGATGCACACTTTGGAAATATACAGCTTATTAA AGACAACTGGGAAGACAGACAAGTAATTGTTGAAAATGTGGGTTCTGTGGAAGGACTTGCCTATCACAGAGCCTGGGATACACTGTACTG GACAAGCTCTACCACCTCATCCATCACCAGACACACTGTGGACCAGACTCGGCCTGGAGCATTTGACAGGGAAGCTGTCATCACCATGTC AGAAGATGACCATCCACATGTGCTAGCCTTGGATGAATGTCAAAATTTAATGTTTTGGACCAACTGGAATGAACAACATCCAAGTATCAT GAGATCTACTCTGACTGGGAAAAATGCTCAAGTGGTGGTCAGTACAGACATACTCACTCCAAATGGACTTACTATCGACTACCGTGCAGA GAAGCTGTATTTCTCAGATGGCAGTCTAGGAAAAATTGAAAGGTGTGAATACGATGGATCCCAGAGACATGTGATAGTTAAATCTGGGCC AGGGACTTTCCTCAGTTTGGCTGTTTATGACAATTATATATTCTGGTCGGACTGGGGAAGAAGAGCTATACTGCGGTCCAACAAGTACAC AGGAGGAGATACAAAAATTCTTCGTTCCGATATTCCACATCAGCCAATGGGAATCATAGCTGTTGCCAATGACACCAATAGCTGTGAACT TTCTCCATGTGCATTATTGAATGGAGGCTGCCATGACTTGTGCCTTTTAACTCCCAATGGGAGAGTGAATTGTTCCTGCAGAGGGGACCG AATATTGCTAGAGGACAACAGATGTGTGACTAAAAATTCCTCCTGCAACGCTTATTCGGAGTTTGAATGTGGAAATGGTGAGTGCATTGA CTACCAGCTCACCTGTGATGGCATTCCTCACTGTAAAGATAAATCAGATGAAAAACTGCTCTACTGTGAAAACAGAAGCTGTCGAAGAGG CTTCAAGCCATGCTATAATCGCCGCTGCATTCCTCATGGCAAGTTATGTGATGGAGAAAATGACTGCGGAGACAACTCTGATGAATTAGA TTGTAAAGTTTCAACCTGTGCCACGGTTGAGTTCCGCTGTGCAGATGGGACTTGTATTCCAAGATCAGCACGATGCAACCAGAACATAGA TTGTGCAGATGCTTCAGATGAAAAGAACTGCAATAACACAGACTGCACACATTTCTATAAGCTTGGAGTGAAAACCACAGGGTTCATAAG ATGTAATTCTACCTCACTGTGTGTTCTGCCAACCTGGATATGCGACGGGTCTAATGACTGTGGAGACTATTCAGATGAATTAAAGTGCCC AGTTCAAAACAAACACAAATGTGAAGAAAATTATTTTAGTTGTCCTAGTGGAAGATGCATTTTGAATACCTGGATATGCGATGGTCAGAA AGATTGTGAGGATGGACGTGATGAATTCCACTGTGATTCTTCTTGCTCTTGGAACCAATTTGCTTGTTCCGCACAAAAATGTATTTCTAA GCATTGGATTTGTGATGGAGAAGATGACTGTGGGGATGGGTTAGATGAAAGTGACAGCATTTGTGGTGCCATAACCTGTGCTGCTGACAT GTTCAGCTGCCAGGGCTCTCGTGCCTGCGTGCCCCGACATTGGCTTTGTGATGGTGAAAGGGACTGTCCAGATGGAAGCGATGAGCTTTC CACAGCAGGCTGCGCTCCCAATAATACATGTGATGAAAATGCTTTCATGTGCCATAATAAAGTATGCATTCCCAAGCAATTTGTTTGTGA CCATGATGACGACTGTGGAGATGGCTCTGATGAGTCACCGCAGTGTGGATATCGACAGTGTGGTACAGAAGAATTTAGTTGTGCTGATGG GCGGTGTCTTCTAAATACTCAATGGCAGTGTGATGGAGACTTTGACTGTCCTGACCATTCTGATGAAGCACCTTTAAACCCAAAGTGTAA AAGTGCAGAACAGTCATGCAACAGTTCATTTTTTATGTGCAAAAATGGCAGGTGCATTCCCAGTGGAGGTCTTTGCGACAATAAGGATGA CTGTGGCGATGGTTCAGATGAGAGAAACTGCCATATAAATGAATGTTTGAGTAAGAAAGTCAGTGGATGTTCTCAAGACTGTCAAGACCT TCCGGTCAGTTATAAGTGCAAATGCTGGCCTGGATTCCAACTGAAGGATGACGGCAAAACATGTGTAGACATTGATGAATGCTCTTCAGG CTTTCCCTGTAGCCAGCAATGCATCAATACATACGGGACTTACAAGTGCCTCTGTACAGATGGGTATGAAATACAACCTGATAACCCAAA TGGCTGCAAATCGCTCTCAGATGAAGAACCTTTTTTAATTCTTGCTGATCATCATGAGATAAGGAAAATTAGCACTGATGGCTCCAACTA CACACTTTTAAAACAGGGATTAAACAATGTTATTGCTATAGACTTTGATTACAGAGAAGAATTCATCTATTGGATCGATTCTAGCCGACC CAATGGCAGTCGCATAAATAGAATGTGTTTAAATGGAAGTGACATTAAGGTAGTTCATAACACAGCGGTCCCCAATGCACTTGCTGTCGA TTGGATTGGAAAAAACCTCTATTGGTCTGACACAGAAAAAAGAATCATTGAAGTATCCAAACTCAATGGCTTGTACCCTACTATACTCGT TAGCAAAAGGCTGAAGTTTCCCAGAGACTTGTCTTTAGATCCTCAAGCTGGATATTTGTATTGGATTGACTGCTGCGAGTATCCTCATAT TGGCCGTGTTGGAATGGATGGAACCAATCAGAGTGTTGTCATAGAAACCAAGATTTCTAGACCTATGGCACTAACAATAGATTATGTTAA TCGTAGACTCTACTGGGCCGATGAAAATCACATTGAATTTAGCAACATGGATGGATCTCATAGACACAAAGTCCCTAATCAAGATATTCC AGGGGTGATTGCACTAACATTGTTTGAAGACTACATCTACTGGACTGATGGGAAAACCAAGTCACTCAGCCGTGCCCATAAAACATCGGG AGCAGACAGACTCTCACTGATTTACTCATGGCATGCCATCACAGATATCCAGGTGTATCATTCTTATAGACAACCTGATGTCTCCAAACA TCTCTGCATGATAAATAATGGTGGTTGCAGTCATTTGTGCCTTTTAGCCCCTGGAAAAACCCACACTTGTGCATGTCCCACTAACTTCTA TCTGGCAGCTGATAATAGGACTTGCTTATCCAACTGCACAGCCAGCCAGTTTCGTTGCAAAACTGACAAATGTATTCCATTCTGGTGGAA ATGTGACACCGTGGATGACTGTGGTGATGGATCTGATGAACCTGATGACTGTCCTGAATTTAGATGTCAGCCAGGCCGATTTCAGTGTGG GACTGGACTCTGTGCTCTACCAGCTTTCATCTGTGATGGAGAGAATGATTGTGGAGACAATTCTGATGAACTCAACTGTGACACACATGT CTGCCTGTCAGGTCAATTCAAATGTACCAAGAACCAGAAATGTATCCCAGTAAACTTAAGATGTAATGGGCAAGATGACTGTGGTGATGA GGAAGATGAAAGAGACTGTCCTGAAAACAGCTGTTCTCCAGACTATTTCCAGTGTAAGACTACGAAGCATTGCATTTCCAAGCTGTGGGT TTGTGACGAGGATCCAGACTGTGCAGATGCATCAGACGAGGCCAACTGCGATAAAAAGACTTGTGGACCTCATGAATTCCAGTGTAAAAA CAACAACTGTATTCCCGATCACTGGCGGTGTGATAGCCAAAATGACTGCAGTGATAATTCAGATGAAGAAAACTGTAAGCCACAGACATG TACATTGAAAGATTTCCTCTGTGCCAATGGGGACTGTGTTTCTTCAAGGTTTTGGTGTGATGGAGATTTTGACTGTGCAGATGGCTCTGA TGAGAGAAATTGTGAGACAAGTTGTTCCAAAGATCAGTTCCGGTGTTCCAATGGTCAGTGTATACCAGCAAAATGGAAATGTGATGGCCA TGAAGACTGCAAATATGGGGAAGATGAGAAAAGCTGTGAGCCAGCTTCTCCTACTTGCTCATCACGTGAATATATATGTGCCAGTGATGG ATGTATTTCAGCATCTTTGAAATGTAATGGAGAATATGATTGTGCTGATGGTTCAGATGAGATGGACTGTGTGACTGAATGTAAGGAAGA TCAGTTTCGGTGCAAAAATAAAGCCCACTGTATTCCAATTAGATGGCTGTGTGATGGAATTCATGACTGTGTGGATGGCAGTGATGAAGA GAACTGTGAAAGAGGAGGAAATATATGTAGAGCTGATGAGTTCCTTTGCAATAATTCTCTCTGCAAACTACATTTCTGGGTGTGTGATGG AGAGGACGACTGTGGAGACAACTCTGATGAAGCCCCTGATATGTGTGTCAAATTTCTTTGTCCATCCACGAGACCTCACAGATGCAGAAA TAACAGAATATGCCTACAGTCGGAGCAAATGTGCAATGGGATTGATGAATGCGGTGACAATTCAGATGAAGATCACTGTGGTGGTAAGCT GACATATAAAGCAAGGCCTTGTAAAAAGGATGAGTTTGCTTGTAGTAATAAAAAATGCATCCCTATGGATCTCCAGTGTGATCGACTTGA TGACTGCGGAGATGGTTCAGATGAGCAAGGATGCAGAATAGCTCCTACTGAATATACCTGTGAAGATAATGTGAATCCATGTGGAGATGA TGCATATTGTAATCAAATAAAAACATCTGTTTTCTGTCGCTGTAAGCCTGGATTTCAGAGAAACATGAAAAACAGACAATGTGAAGACCT TAATGAATGTTTGGTGTTTGGCACATGTTCCCATCAATGTATAAATGTGGAAGGATCATATAAATGTGTGTGTGACCAGAATTTTCAAGA AAGAAATAACACCTGCATAGCAGAAGGCTCTGAAGATCAAGTTCTCTACATTGCTAATGACACTGATATCCTGGGTTTTATATATCCATT CAACTACAGTGGCGATCATCAACAAATTTCTCATATTGAACATAATTCAAGAATAACAGGGATGGATGTATATTATCAAAGAGATATGAT TATTTGGAGTACTCAGTTTAATCCAGGCGGAATTTTCTACAAAAGGATCCATGGCAGAGAAAAAAGGCAAGCAAACAGTGGCTTGATTTG TCCTGAATTTAAAAGGCCCAGGGACATTGCAGTTGACTGGGTGGCTGGAAACATTTACTGGACTGATCATTCTAGAATGCATTGGTTCAG TTACTACACTACTCACTGGACCAGTCTGAGGTACTCTATCAACGTAGGGCAGCTGAATGGCCCCAACTGCACCAGACTCTTAACAAATAT GGCTGGAGAACCCTATGCTATTGCAGTAAATCCTAAAAGAGGGATGATGTACTGGACTGTTGTTGGGGATCATTCCCATATAGAAGAAGC AGCCATGGATGGTACACTGAGAAGGATTTTAGTACAAAAGAACTTACAGAGACCCACAGGTTTGGCTGTGGATTATTTTAGTGAACGCAT ATATTGGGCTGACTTTGAGCTCTCCATCATTGGCAGTGTTCTGTATGATGGCTCTAATTCAGTAGTCTCTGTCAGCAGCAAACAAGGTTT ATTACATCCACATAGGATCGATATCTTTGAAGATTATATATATGGAGCAGGACCTAAAAATGGTGTATTTCGAGTTCAAAAATTTGGCCA TGGTTCAGTAGAGTACTTAGCTTTAAATATTGATAAAACAAAAGGTGTTTTGATATCTCATCGTTATAAACAACTAGATTTACCCAATCC ATGCTTGGATTTAGCATGCGAATTTCTTTGCTTGCTAAATCCTTCTGGGGCCACTTGTGTGTGTCCAGAAGGAAAATATTTGATTAATGG CACCTGCAATGATGACAGCCTGTTAGATGATTCATGTAAGTTAACTTGTGAAAATGGAGGAAGATGCATTTTAAATGAGAAAGGTGATTT GAGGTGTCACTGTTGGCCCAGTTATTCAGGAGAAAGATGTGAAGTCAACCACTGTAGCAACTACTGCCAGAATGGAGGAACTTGCGTACC ATCAGTTCTAGGGAGACCCACCTGCAGCTGTGCACTGGGTTTCACTGGGCCAAACTGTGGTAAGACAGTCTGTGAGGATTTTTGTCAAAA TGGAGGAACCTGCATTGTGACTGCTGGAAACCAGCCTTACTGCCACTGCCAGCCGGAATACACCGGAGACAGATGTCAGTACTACGTGTG CCACCACTATTGTGTGAATTCTGAATCATGTACCATTGGGGATGATGGAAGTGTTGAATGTGTCTGTCCAACGCGCTATGAAGGACCAAA ATGTGAGGTTGACAAGTGTGTAAGGTGCCATGGGGGGCACTGCATTATAAATAAAGACAGTGAAGATATATTTTGCAACTGCACTAATGG AAAGATTGCCTCTAGCTGTCAGTTATGTGATGGCTACTGTTACAATGGTGGCACATGCCAGCTGGACCCCGAGACAAATGTACCTGTGTG TCTATGCTCCACCAACTGGTCAGGCACACAGTGTGAAAGGCCAGCCCCAAAGAGCAGCAAGTCTGATCATATCAGCACAAGAAGCATTGC CATCATTGTGCCTCTCGTCCTCTTGGTGACTTTGATAACCACCTTAGTAATTGGTTTAGTGCTTTGTAAAAGAAAAAGAAGGACAAAAAC AATTAGAAGACAACCTATTATCAATGGAGGAATAAATGTAGAAATTGGCAATCCATCTTATAACATGTATGAGGTAGATCATGATCACAA CGATGGAGGTCTTTTAGATCCTGGCTTTATGATAGACCCAACAAAGGCCAGGTACATAGGGGGAGGACCCAGTGCTTTCAAGCTTCCACA CACAGCGCCGCCCATCTACCTAAACTCTGATTTGAAAGGACCACTAACTGCTGGGCCAACAAATTACTCCAATCCGGTATATGCAAAATT ATATATGGATGGGCAAAACTGTCGAAACTCCTTAGGAAGTGTTGATGAAAGGAAAGAACTGCTTCCAAAGAAAATAGAAATTGGTATAAG AGAGACAGTGGCATAATCAGTGATATCTTTTATATGCTGTATAAATGTATAAAATATAAGGATTACTTTTGTATGTTCCAACAGTATTAT ACTTGTTTTGGCATCAGCATTACCTCTTTCTTTATCTTTTTCCTGGTTAATTGTTTTCTGAGTTTTTTGGGTTTTATTTTTTGCTGATGA CTATTGATTGACCATTTGTATGGTATTTTTATGAAAAAGAACTGCACTACAGTACAATTTACAACAATGCTGCTGATATGACACACCTTT GAATTTGTTAAAATTAAAAACAACGTATTCCTTTGTAGTGTGAATATGAGCAATCTATTTTATATGAACTTTTTTGGTTGTACTTAATCA ACGAGGAGAATCTCTGCACTTTTCCATTATACGGTTTGAAGGCTGTAATACAGTGTCATATTATTTTTCTGTTTAAATTGATGGAAAAAT GATTGAATGGTCAACTCTCTTCTTTGTGCCCATAAAGATCGATTCAGACTCTGCTGAAAATATATAGCTCTCACAAGTTCAGCATCACCT GCTTTGAAATTAGCCTTAGATTGCCAACCAATAGATGAGAATTTTGAGGAAAAAAATTAAAAATATGTAAAATTAATAATTTGCATGAAC ACAGATGACTACATTTTCCAAAACTTAGTGGACTCTATGTGATGTACTAAATGTATACACCTTGTAAGCAATAGTTATATTTAGGTGGTA GAACATAGCAAAAATATAACCGAAAGTTGGCCGACTGCACTTGCTATGGAATAAGACCTTTTATTCTCCCTCAGTCTCGAGATAAATAGC CAGCCTAGAGCACAACAGGGCATTGGGTACTTGCATCTTAGGTATTTCTTCCCAGTCACATCCATTTTGTGGAAGATTAACCCAACCCCT TACACTACACTGAACACTAAAGAATAATATATAAGCACACAAATTGGTGACAGAATTTCAATTACGTGAACGCATCCTCTTTGCTAGGTC AAAAAACAAAGGGCAAAGCAGACATTTTAGTATACAGAGTGATTGGCAAATATTTTCAAGATTTAATATGAGCAACCCATTATTTGCCCT ATCCAAAATATATTCAAGGGCCTTCCAAGTTGTAGAAGAACAATGATCTTCCCATAATCAAAAGTGGAGAGTCGAAATGCTGTGCCAGTT GCTCTGGTATTCAGGTTTCTCTGGGTTTTACAGAACGCATGGACCCCATTCACGTTTGGTTTGTTTATCTTCAAATTTGAGTTGAAACGA GTGCGATTTATTTAAGTTGTATATAAAAATAAAAGGATAGCATTTTTATACAAATATCTTTAAAGGCACAAAAGATTTATTCACAAGTTT TGGAGGGCTTTTTGTTCCTCTGATAGACATGACTGACTTTTAGCTGTCATAATGTATTAACCTAACAGATGAAATATGTTAAATATGTGG TTGCTCTTTATCCCTTTGTACAAGCATTAAAAAAACTGCTGTTTTATAAGAAGACTTTTTGTTGTACTATGTGCATGCATACTACCTATT TCTAAACTTTGCCATATTGAGGCCTTTATAAACTATTGATTTATGTAATACTAGTGCAATTTTGCTTGAACAATGTTATGCATATCATAA ACTTTTTCAGGTTCTTGTTTAAGTACATTTTTTAAATTGAACAGTATTTTTCATTTTGGTTATAATATAGTCATTTTGCCTATGTTTCTA >98483_98483_1_VPS53-LRP1B_VPS53_chr17_463666_ENST00000446250_LRP1B_chr2_142012210_ENST00000389484_length(amino acids)=4492AA_BP=7 MSGHHPAELLSNCQQLNCQYKCTMVRNSTRCYCEDGFEITEDGRSCKDQDECAVYGTCSQTCRNTHGSYTCSCVEGYLMQPDNRSCKAKI EPTDRPPILLIANFETIEVFYLNGSKMATLSSVNGNEIHTLDFIYNEDMICWIESRESSNQLKCIQITKAGGLTDEWTINILQSFHNVQQ MAIDWLTRNLYFVDHVGDRIFVCNSNGSVCVTLIDLELHNPKAIAVDPIAGKLFFTDYGNVAKVERCDMDGMNRTRIIDSKTEQPAALAL DLVNKLVYWVDLYLDYVGVVDYQGKNRHTVIQGRQVRHLYGITVFEDYLYATNSDNYNIVRINRFNGTDIHSLIKIENAWGIRIYQKRTQ PTVRSHACEVDPYGMPGGCSHICLLSSSYKTRTCRCRTGFNLGSDGRSCKRPKNELFLFYGKGRPGIVRGMDLNTKIADEYMIPIENLVN PRALDFHAETNYIYFADTTSFLIGRQKIDGTERETILKDDLDNVEGIAVDWIGNNLYWTNDGHRKTINVARLEKASQSRKTLLEGEMSHP RGIVVDPVNGWMYWTDWEEDEIDDSVGRIEKAWMDGFNRQIFVTSKMLWPNGLTLDFHTNTLYWCDAYYDHIEKVFLNGTHRKIVYSGRE LNHPFGLSHHGNYVFWTDYMNGSIFQLDLITSEVTLLRHERPPLFGLQIYDPRKQQGDNMCRVNNGGCSTLCLAIPGGRVCACADNQLLD ENGTTCTFNPGEALPHICKAGEFRCKNRHCIQARWKCDGDDDCLDGSDEDSVNCFNHSCPDDQFKCQNNRCIPKRWLCDGANDCGSNEDE SNQTCTARTCQVDQFSCGNGRCIPRAWLCDREDDCGDQTDEMASCEFPTCEPLTQFVCKSGRCISSKWHCDSDDDCGDGSDEVGCVHSCF DNQFRCSSGRCIPGHWACDGDNDCGDFSDEAQINCTKEEIHSPAGCNGNEFQCHPDGNCVPDLWRCDGEKDCEDGSDEKGCNGTIRLCDH KTKFSCWSTGRCINKAWVCDGDIDCEDQSDEDDCDSFLCGPPKHPCANDTSVCLQPEKLCNGKKDCPDGSDEGYLCDECSLNNGGCSNHC SVVPGRGIVCSCPEGLQLNKDNKTCEIVDYCSNHLKCSQVCEQHKHTVKCSCYEGWKLDVDGESCTSVDPFEAFIIFSIRHEIRRIDLHK RDYSLLVPGLRNTIALDFHFNQSLLYWTDVVEDRIYRGKLSESGGVSAIEVVVEHGLATPEGLTVDWIAGNIYWIDSNLDQIEVAKLDGS LRTTLIAGAMEHPRAIALDPRYGILFWTDWDANFPRIESASMSGAGRKTIYKDMKTGAWPNGLTVDHFEKRIVWTDARSDAIYSALYDGT NMIEIIRGHEYLSHPFAVSLYGSEVYWTDWRTNTLSKANKWTGQNVSVIQKTSAQPFDLQIYHPSRQPQAPNPCAANDGKGPCSHMCLIN HNRSAACACPHLMKLSSDKKTCYEMKKFLLYARRSEIRGVDIDNPYFNFITAFTVPDIDDVTVIDFDASEERLYWTDIKTQTIKRAFING TGLETVISRDIQSIRGLAVDWVSRNLYWISSEFDETQINVARLDGSLKTSIIHGIDKPQCLAAHPVRGKLYWTDGNTINMANMDGSNSKI LFQNQKEPVGLSIDYVENKLYWISSGNGTINRCNLDGGNLEVIESMKEELTKATALTIMDKKLWWADQNLAQLGTCSKRDGRNPTILRNK TSGVVHMKVYDKEAQQGSNSCQLNNGGCSQLCLPTSETTRTCMCTVGYYLQKNRMSCQGIESFLMYSVHEGIRGIPLEPSDKMDALMPIS GTSFAVGIDFHAENDTIYWTDMGFNKISRAKRDQTWKEDIITNGLGRVEGIAVDWIAGNIYWTDHGFNLIEVARLNGSFRYVIISQGLDQ PRSIAVHPEKGLLFWTEWGQMPCIGKARLDGSEKVVLVSMGIAWPNGISIDYEENKLYWCDARTDKIERIDLETGGNREMVLSGSNVDMF SVAVFGAYIYWSDRAHANGSVRRGHKNDATETITMRTGLGVNLKEVKIFNRVREKGTNVCARDNGGCKQLCLYRGNSRRTCACAHGYLAE DGVTCLRHEGYLLYSGRTILKSIHLSDETNLNSPIRPYENPRYFKNVIALAFDYNQRRKGTNRIFYSDAHFGNIQLIKDNWEDRQVIVEN VGSVEGLAYHRAWDTLYWTSSTTSSITRHTVDQTRPGAFDREAVITMSEDDHPHVLALDECQNLMFWTNWNEQHPSIMRSTLTGKNAQVV VSTDILTPNGLTIDYRAEKLYFSDGSLGKIERCEYDGSQRHVIVKSGPGTFLSLAVYDNYIFWSDWGRRAILRSNKYTGGDTKILRSDIP HQPMGIIAVANDTNSCELSPCALLNGGCHDLCLLTPNGRVNCSCRGDRILLEDNRCVTKNSSCNAYSEFECGNGECIDYQLTCDGIPHCK DKSDEKLLYCENRSCRRGFKPCYNRRCIPHGKLCDGENDCGDNSDELDCKVSTCATVEFRCADGTCIPRSARCNQNIDCADASDEKNCNN TDCTHFYKLGVKTTGFIRCNSTSLCVLPTWICDGSNDCGDYSDELKCPVQNKHKCEENYFSCPSGRCILNTWICDGQKDCEDGRDEFHCD SSCSWNQFACSAQKCISKHWICDGEDDCGDGLDESDSICGAITCAADMFSCQGSRACVPRHWLCDGERDCPDGSDELSTAGCAPNNTCDE NAFMCHNKVCIPKQFVCDHDDDCGDGSDESPQCGYRQCGTEEFSCADGRCLLNTQWQCDGDFDCPDHSDEAPLNPKCKSAEQSCNSSFFM CKNGRCIPSGGLCDNKDDCGDGSDERNCHINECLSKKVSGCSQDCQDLPVSYKCKCWPGFQLKDDGKTCVDIDECSSGFPCSQQCINTYG TYKCLCTDGYEIQPDNPNGCKSLSDEEPFLILADHHEIRKISTDGSNYTLLKQGLNNVIAIDFDYREEFIYWIDSSRPNGSRINRMCLNG SDIKVVHNTAVPNALAVDWIGKNLYWSDTEKRIIEVSKLNGLYPTILVSKRLKFPRDLSLDPQAGYLYWIDCCEYPHIGRVGMDGTNQSV VIETKISRPMALTIDYVNRRLYWADENHIEFSNMDGSHRHKVPNQDIPGVIALTLFEDYIYWTDGKTKSLSRAHKTSGADRLSLIYSWHA ITDIQVYHSYRQPDVSKHLCMINNGGCSHLCLLAPGKTHTCACPTNFYLAADNRTCLSNCTASQFRCKTDKCIPFWWKCDTVDDCGDGSD EPDDCPEFRCQPGRFQCGTGLCALPAFICDGENDCGDNSDELNCDTHVCLSGQFKCTKNQKCIPVNLRCNGQDDCGDEEDERDCPENSCS PDYFQCKTTKHCISKLWVCDEDPDCADASDEANCDKKTCGPHEFQCKNNNCIPDHWRCDSQNDCSDNSDEENCKPQTCTLKDFLCANGDC VSSRFWCDGDFDCADGSDERNCETSCSKDQFRCSNGQCIPAKWKCDGHEDCKYGEDEKSCEPASPTCSSREYICASDGCISASLKCNGEY DCADGSDEMDCVTECKEDQFRCKNKAHCIPIRWLCDGIHDCVDGSDEENCERGGNICRADEFLCNNSLCKLHFWVCDGEDDCGDNSDEAP DMCVKFLCPSTRPHRCRNNRICLQSEQMCNGIDECGDNSDEDHCGGKLTYKARPCKKDEFACSNKKCIPMDLQCDRLDDCGDGSDEQGCR IAPTEYTCEDNVNPCGDDAYCNQIKTSVFCRCKPGFQRNMKNRQCEDLNECLVFGTCSHQCINVEGSYKCVCDQNFQERNNTCIAEGSED QVLYIANDTDILGFIYPFNYSGDHQQISHIEHNSRITGMDVYYQRDMIIWSTQFNPGGIFYKRIHGREKRQANSGLICPEFKRPRDIAVD WVAGNIYWTDHSRMHWFSYYTTHWTSLRYSINVGQLNGPNCTRLLTNMAGEPYAIAVNPKRGMMYWTVVGDHSHIEEAAMDGTLRRILVQ KNLQRPTGLAVDYFSERIYWADFELSIIGSVLYDGSNSVVSVSSKQGLLHPHRIDIFEDYIYGAGPKNGVFRVQKFGHGSVEYLALNIDK TKGVLISHRYKQLDLPNPCLDLACEFLCLLNPSGATCVCPEGKYLINGTCNDDSLLDDSCKLTCENGGRCILNEKGDLRCHCWPSYSGER CEVNHCSNYCQNGGTCVPSVLGRPTCSCALGFTGPNCGKTVCEDFCQNGGTCIVTAGNQPYCHCQPEYTGDRCQYYVCHHYCVNSESCTI GDDGSVECVCPTRYEGPKCEVDKCVRCHGGHCIINKDSEDIFCNCTNGKIASSCQLCDGYCYNGGTCQLDPETNVPVCLCSTNWSGTQCE RPAPKSSKSDHISTRSIAIIVPLVLLVTLITTLVIGLVLCKRKRRTKTIRRQPIINGGINVEIGNPSYNMYEVDHDHNDGGLLDPGFMID -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for VPS53-LRP1B |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for VPS53-LRP1B |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for VPS53-LRP1B |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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