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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:VPS8-MBOAT2 (FusionGDB2 ID:98517)

Fusion Gene Summary for VPS8-MBOAT2

check button Fusion gene summary
Fusion gene informationFusion gene name: VPS8-MBOAT2
Fusion gene ID: 98517
HgeneTgene
Gene symbol

VPS8

MBOAT2

Gene ID

23355

129642

Gene nameVPS8 subunit of CORVET complexmembrane bound O-acyltransferase domain containing 2
SynonymsKIAA0804LPAAT|LPCAT4|LPEAT|LPLAT 2|OACT2
Cytomap

3q27.2

2p25.1

Type of geneprotein-codingprotein-coding
Descriptionvacuolar protein sorting-associated protein 8 homologVPS8, CORVET complex subunitvacuolar protein sorting 8 homologlysophospholipid acyltransferase 21-acylglycerophosphate O-acyltransferase1-acylglycerophosphoethanolamine O-acyltransferaseO-acyltransferase (membrane bound) domain containing 2lyso-PA acyltransferaselyso-PE acyltransferaselysophosphatidic acid acy
Modification date2020031320200320
UniProtAcc.

Q6ZWT7

Ensembl transtripts involved in fusion geneENST00000287546, ENST00000436792, 
ENST00000437079, ENST00000446204, 
ENST00000424463, ENST00000463687, 
ENST00000486484, ENST00000305997, 
Fusion gene scores* DoF score15 X 8 X 7=84014 X 12 X 9=1512
# samples 1715
** MAII scorelog2(17/840*10)=-2.30485458152842
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(15/1512*10)=-3.33342373372519
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: VPS8 [Title/Abstract] AND MBOAT2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointVPS8(184658031)-MBOAT2(9048846), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across VPS8 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across MBOAT2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4GBMTCGA-06-0171-02AVPS8chr3

184658031

+MBOAT2chr2

9048846

-


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Fusion Gene ORF analysis for VPS8-MBOAT2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000287546ENST00000486484VPS8chr3

184658031

+MBOAT2chr2

9048846

-
5CDS-5UTRENST00000436792ENST00000486484VPS8chr3

184658031

+MBOAT2chr2

9048846

-
5CDS-5UTRENST00000437079ENST00000486484VPS8chr3

184658031

+MBOAT2chr2

9048846

-
5CDS-5UTRENST00000446204ENST00000486484VPS8chr3

184658031

+MBOAT2chr2

9048846

-
In-frameENST00000287546ENST00000305997VPS8chr3

184658031

+MBOAT2chr2

9048846

-
In-frameENST00000436792ENST00000305997VPS8chr3

184658031

+MBOAT2chr2

9048846

-
In-frameENST00000437079ENST00000305997VPS8chr3

184658031

+MBOAT2chr2

9048846

-
In-frameENST00000446204ENST00000305997VPS8chr3

184658031

+MBOAT2chr2

9048846

-
intron-3CDSENST00000424463ENST00000305997VPS8chr3

184658031

+MBOAT2chr2

9048846

-
intron-3CDSENST00000463687ENST00000305997VPS8chr3

184658031

+MBOAT2chr2

9048846

-
intron-5UTRENST00000424463ENST00000486484VPS8chr3

184658031

+MBOAT2chr2

9048846

-
intron-5UTRENST00000463687ENST00000486484VPS8chr3

184658031

+MBOAT2chr2

9048846

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000437079VPS8chr3184658031+ENST00000305997MBOAT2chr29048846-10459320615344691438
ENST00000287546VPS8chr3184658031+ENST00000305997MBOAT2chr29048846-10459320615344691438
ENST00000436792VPS8chr3184658031+ENST00000305997MBOAT2chr29048846-10425317212544351436
ENST00000446204VPS8chr3184658031+ENST00000305997MBOAT2chr29048846-10143289011341531346

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000437079ENST00000305997VPS8chr3184658031+MBOAT2chr29048846-0.0001073610.9998926
ENST00000287546ENST00000305997VPS8chr3184658031+MBOAT2chr29048846-0.0001068830.99989307
ENST00000436792ENST00000305997VPS8chr3184658031+MBOAT2chr29048846-0.0001029650.999897
ENST00000446204ENST00000305997VPS8chr3184658031+MBOAT2chr29048846-9.98E-050.9999002

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Fusion Genomic Features for VPS8-MBOAT2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for VPS8-MBOAT2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr3:184658031/chr2:9048846)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.MBOAT2

Q6ZWT7

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Acyltransferase which catalyzes the transfert of an acyl group from an acyl-CoA to a lysophospholipid leading to the production of a phospholipid and participates in the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle (PubMed:18772128). Catalyzes preferentially the acylation of lysophosphatidylethanolamine (1-acyl-sn-glycero-3-phosphoethanolamine or LPE) and lysophosphatidic acid (LPA) and to a lesser extend lysophosphatidylcholine (LPC) and lysophosphatidylserine (LPS) (PubMed:18772128). Prefers oleoyl-CoA as the acyl donor (PubMed:18772128). May be involved in chondrocyte differentiation (By similarity). {ECO:0000250|UniProtKB:Q8R3I2, ECO:0000269|PubMed:18772128}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneVPS8chr3:184658031chr2:9048846ENST00000436792+3547195_23610091427.0RepeatNote=WD
HgeneVPS8chr3:184658031chr2:9048846ENST00000437079+3648195_23610111429.0RepeatNote=WD
HgeneVPS8chr3:184658031chr2:9048846ENST00000446204+3345195_2369191337.0RepeatNote=WD
TgeneMBOAT2chr3:184658031chr2:9048846ENST00000305997213184_20499521.0TransmembraneHelical
TgeneMBOAT2chr3:184658031chr2:9048846ENST00000305997213237_25799521.0TransmembraneHelical
TgeneMBOAT2chr3:184658031chr2:9048846ENST00000305997213264_28499521.0TransmembraneHelical
TgeneMBOAT2chr3:184658031chr2:9048846ENST00000305997213366_38699521.0TransmembraneHelical
TgeneMBOAT2chr3:184658031chr2:9048846ENST00000305997213416_43699521.0TransmembraneHelical
TgeneMBOAT2chr3:184658031chr2:9048846ENST00000305997213444_46499521.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneVPS8chr3:184658031chr2:9048846ENST00000436792+35471258_131010091427.0Zinc fingerRING-type%3B atypical
HgeneVPS8chr3:184658031chr2:9048846ENST00000437079+36481258_131010111429.0Zinc fingerRING-type%3B atypical
HgeneVPS8chr3:184658031chr2:9048846ENST00000446204+33451258_13109191337.0Zinc fingerRING-type%3B atypical
TgeneMBOAT2chr3:184658031chr2:9048846ENST0000030599721322_4299521.0TransmembraneHelical
TgeneMBOAT2chr3:184658031chr2:9048846ENST0000030599721361_8199521.0TransmembraneHelical
TgeneMBOAT2chr3:184658031chr2:9048846ENST0000030599721388_10899521.0TransmembraneHelical


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Fusion Gene Sequence for VPS8-MBOAT2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>98517_98517_1_VPS8-MBOAT2_VPS8_chr3_184658031_ENST00000287546_MBOAT2_chr2_9048846_ENST00000305997_length(transcript)=10459nt_BP=3206nt
AGGTAGTGCGCGTGCGTGAGGCTAGAGCAGTGGGTGCGGTCACGTGGGCCGGCGGTCCACGGCCGGAATGGCAGCAAGCTCAGAGATAAT
CATTCAGGTCTTCGTGAGCTAAGGCCAAACAAACAAAAAACACTTGCTTTGATGGACTGAATACTGTTATTAGAAGTAAATATGGAAAAT
GAACCAGACCATGAAAATGTGGAACAGAGCCTCTGTGCCAAGACGAGCGAAGAAGAGCTGAATAAGTCTTTCAATCTAGAAGCTTCACTT
TCAAAATTCTCTTACATAGATATGGACAAGGAACTGGAGTTCAAAAATGATCTGATTGATGACAAGGAGTTTGATATTCCTCAAGTTGAT
ACTCCTCCAACACTGGAAAGCATACTAAATGAGACTGATGATGAAGATGAGTCTTTTATTCTTGAGGATCCTACATTGTTAAACATTGAT
ACTATTGATTCTCACTCCTATGATACTTCATCTGTGGCAAGCTCAGATAGTGGTGACAGGACCAACTTAAAAAGGAAGAAGAAATTACCT
GATTCTTTTTCACTTCATGGATCAGTTATGCGCCATTCACTTTTGAAGGGAATTTCTGCCCAGATAGTGTCTGCAGCTGACAAAGTAGAT
GCTGGCTTGCCTACAGCAATTGCAGTATCCAGTCTGATAGCAGTGGGTACATCTCATGGATTGGCTTTAATATTTGGTAAATATCAGAAT
CAAGCTTTGCGACTCTGTCTGGGTAGCACTAGTGTTGGAGGTCAGTATGGCGCTATCTCTGCCCTCAGTATCAACAATGATTGCTCAAGA
CTTCTTTGTGGCTTTGCTAAAGGACAGATCACCATGTGGGATTTGGCCAGTGGAAAACTTCTAAGATCAATAACAGATGCTCATCCTCCA
GGAACAGCAATATTGCATATCAAGTTTACAGATGATCCAACTCTTGCAATTTGCAACGACAGCGGAGGCTCTGTTTTTGAATTGACATTT
AAGAGAGTGATGGGAGTGAGAACCTGTGAATCTAGATGTCTGTTCAGTGGTTCCAAGGGTGAAGTCTGCTGTATTGAGCCTCTGCATTCT
AAGCCTGAGTTGAAAGATCATCCCATCACACAGTTTTCATTATTGGCCATGGCATCCTTGACAAAAATACTGGTCATTGGATTGAAACCA
TCCTTGAAAGTATGGATGACTTTTCCCTATGGCCGGATGGATCCTTCCAGTGTGCCACTGCTGGCCTGGCACTTTGTAGCAGTACAAAAT
TACGTGAATCCCATGCTTGCCTTCTGCAGAGGAGATGTTGTTCATTTTCTATTGGTAAAGAGAGATGAATCTGGAGCAATACATGTTACT
AAGCAAAAGCATCTTCACCTATACTATGACCTCATCAACTTTACCTGGATAAATTCACGCACAGTTGTGCTCTTAGACAGCGTAGAGAAG
TTGCATGTGATTGATCGGCAAACACAAGAGGAATTGGAGACAGTGGAGATCTCAGAAGTTCAGCTGGTCTACAATAGCAGCCATTTCAAA
TCACTAGCCACTGGAGGAAATGTTAGCCAGGCACTGGCTTTGGTTGGAGAGAAGGCTTGTTATCAATCCATCAGTAGCTATGGTGGTCAG
ATCTTTTATTTGGGGACAAAATCTGTTTATGTGATGATGCTGAGGAGCTGGAGAGAGAGAGTGGATCATCTCCTGAAACAAGATTGTCTT
ACAGAAGCGTTGGCTCTTGCGTGGTCTTTCCATGAAGGAAAAGCAAAAGCAGTAGTGGGATTATCAGGGGATGCCAGTAAGCGAAAGGCT
ATTGTTGCAGACCGGATGGTAGAAATCCTATTCCATTATGCAGATCGAGCTCTGAAAAAGTGCCCAGACCAAGGAAAAATCCAAGTGATG
GAGCAGCATTTTCAGGATATGGTGCCTGTCATAGTTGATTACTGCCTTCTGCTGCAGCGAAAGGATCTTTTATTTAGTCAGATGTATGAT
AAATTAAGTGAGAATTCAGTGGCCAAAGGAGTATTTTTGGAGTGCCTTGAGCCATATATTTTAAGTGATAAATTGGTGGGAATCACACCC
CAAGTAATGAAAGACTTGATTGTTCATTTCCAAGATAAAAAATTAATGGAAAATGTGGAAGCGCTCATTGTACATATGGATATCACCAGC
CTAGATATTCAGCAGGTAGTTCTCATGTGTTGGGAAAATCGTTTATATGATGCTATGATCTATGTCTACAACAGAGGCATGAATGAATTT
ATTAGTCCAATGGAGAAACTTTTCAGAGTCATTGCTCCTCCTCTGAATGCAGGAAAAACACTAACAGATGAACAAGTTGTTATGGGCAAT
AAGCTCCTTGTATATATTAGCTGTTGTCTAGCAGGTCGTGCCTATCCCCTTGGTGACATCCCTGAAGATCTGGTTCCCTTGGTTAAAAAC
CAGGTTTTTGAATTTCTAATTCGCCTGCATTCAGCAGAGGCTTCTCCTGAGGAAGAAATCTATCCTTACATTCGGACTTTGCTACATTTT
GACACAAGAGAATTTCTAAATGTATTGGCACTGACTTTTGAAGATTTTAAAAATGACAAGCAAGCTGTGGAATATCAACAGCGAATTGTG
GATATTTTGTTGAAAGTTATGGTGGAGAATTCAGACTTTACCCCCTCACAAGTAGGATGTCTCTTTACCTTCCTTGCTCGGCAGCTTGCA
AAGCCTGACAACACCTTGTTTGTAAACAGAACACTTTTTGATCAGGTCCTTGAATTCCTTTGTAGTCCTGACGATGACTCCCGACACTCT
GAAAGACAGCAGGTCCTTTTAGAATTGCTGCAGGCTGGAGGCATAGTTCAATTTGAAGAGAGTCGACTCATCCGGATGGCAGAAAAAGCT
GAGTTCTATCAAATTTGTGAATTTATGTATGAAAGAGAACACCAATATGATAAAATTATTGATTGCTACTTACGTGACCCTCTGCGAGAG
GAAGAAGTCTTTAATTACATTCACAATATCTTATCCATTCCCGGACACAGTGCAGAGGAGAAGCAGTCTGTATGGCAGAAAGCAATGGAT
CATATTGAGGAACTCGTGTCCCTGAAGCCTTGTAAAGCTGCGGAGCTGGTTGCCACCCACTTTTCTGGACATATTGAAACGGTCATTAAA
AAACTTCAGAACCAGGTTTTGCTTTTCAAATTTTTGAGGAGTCTTCTTGACCCAAGTTACTGCTTTGTGTTTGCTCTGGGATACCTCACA
GTGTGCCAAGTTACTCGAGTCTATATCTTTGACTATGGACAATATTCTGCTGATTTTTCAGGCCCAATGATGATCATTACTCAGAAGATC
ACTAGTTTGGCTTGCGAAATTCATGATGGGATGTTTCGGAAGGATGAAGAACTGACTTCCTCACAGAGGGATTTAGCTGTAAGGCGCATG
CCAAGCTTACTGGAGTATTTGAGTTACAACTGTAACTTCATGGGGATCCTGGCAGGCCCACTTTGCTCTTACAAAGACTACATTACTTTC
ATTGAAGGCAGATCATACCATATCACACAATCTGGTGAAAATGGAAAAGAAGAGACACAGTATGAAAGAACAGAGCCATCTCCAAATACT
GCGGTTGTTCAGAAGCTCTTAGTTTGTGGGCTGTCCTTGTTATTTCACTTGACCATCTGTACAACATTACCTGTGGAGTACAACATTGAT
GAGCATTTTCAAGCTACAGCTTCGTGGCCAACAAAGATTATCTATCTGTATATCTCTCTTTTGGCTGCCAGACCCAAATACTATTTTGCA
TGGACGCTAGCTGATGCCATTAATAATGCTGCAGGCTTTGGTTTCAGAGGGTATGACGAAAATGGAGCAGCTCGCTGGGACTTAATTTCC
AATTTGAGAATTCAACAAATAGAGATGTCAACAAGTTTCAAGATGTTTCTTGATAATTGGAATATTCAGACAGCTCTTTGGCTCAAAAGG
GTGTGTTATGAACGAACCTCCTTCAGTCCAACTATCCAGACGTTCATTCTCTCTGCCATTTGGCACGGGGTATACCCAGGATATTATCTA
ACGTTTCTAACAGGGGTGTTAATGACATTAGCAGCAAGAGCTATGAGAAATAACTTTAGACATTATTTCATTGAACCTTCCCAACTGAAA
TTATTTTATGATGTTATAACATGGATAGTAACTCAAGTAGCAATAAGTTACACAGTTGTGCCATTTGTGCTTCTTTCTATAAAACCATCA
CTCACGTTTTACAGCTCCTGGTATTATTGCCTGCACATTCTTGGTATCTTAGTATTATTGTTGTTGCCAGTGAAAAAAACTCAAAGAAGA
AAGAATACACATGAAAACATTCAGCTCTCACAATCCAAAAAGTTTGATGAAGGAGAAAATTCTTTGGGACAGAACAGTTTTTCTACAACA
AACAATGTTTGCAATCAGAATCAAGAAATAGCCTCGAGACATTCATCACTAAAGCAGTGATCGGGAAGGCTCTGAGGGCTGTTTTTTTTT
TTTGATGTTAACAGAAACCAATCTTAGCACCTTTTCAAGGGGTTTGAGTTTGTTGGAAAAGCAGTTAACTGGGGGGAAATGGACAGTTAT
AGATAAGGAATTTCCTGTACACCAGATTGGAAATGGAGTGAAACAAGCCCTCCCATGCCATGTCTCCGTGGGCCACGCCTTATGTAAGAA
TATTTCCATATTTCAGTGGGCACTCCCAACCTCAGCACTTGTCCGTAGGGTCACACGCGTGCCCTGTTGCTGAATGTATGTTGCGTATCC
CAAGGCACTGAAGAGGTGGAAAAATAATCGTGTCAATCTGGATGATAGAGAGAAATTAACTTTTCCAAATGAATGTCTTGCCTTAAACCC
TCTATTTCCTAAAATATTGTTCCTAAATGGTATTTTCAAGTGTAATATTGTGAGAACGCTACTGCAGTAGTTGATGTTGTGTGCTGTAAA
GGATTTTAGGAGGAATTTGAAACAGGATATTTAAGAGTGTGGATATTTTTAAAATGCAATAAACATCTCAGTATTTGAAGGGTTTTCTTA
AAGTATGTCAAATGACTACAATCCATAGTGAAACTGTAAACAGTAATGGACGCCAAATTATAGGTAGCTGATTTTGCTGGAGAGTTTAAT
TACCTTGTGCAGTCAAAGAGCGCTTCCAGAAGGAATCTCTTAAAACATAATGAGAGGTTTGGTAATGTGATATTTTAAGCTTATTCTTTT
TCTTAAAAGAGAGAGGTGACGAAGGAAGGCAGGAATGAAGAAGCACTGCGTGGCCTCCGGTGGAATGCACGGGGCACAGCCGCGACTCTG
CAGGCAGCTTCCCCCCCATGCCAGGGCTCTGCGCCGTCATGTGAGACTTAAAAAAAAAGTTGAATGACTTCGTGATACTTTGGACTTCTA
AATTAAATTTATCAGGCATAAATTATGTAGAATTAGAGGCTTTGAAAATAATACTGGTAGGTTGCTCAAAGGTTTTGAAAGAGAAATCGC
TAGGTAGGTTACTATCTGGCTAATCCATTTCTTATCCTTGACAATTTAATTCATATTTGGGAAACTTTTAGGGAAATGAAAAATAAAAGT
CACTGAGTCTGGGTGACATTTTTTAAGAATAATATAAATTCAGTTTCAAACTCTTCTCACATTAAAATTTTGCTGTGAACTCTTACTAAA
ATGAGTTTTAGGTTCTGTAAGTGGAAAAATGTGCTTTTATTTTATGGGCCATTTTTACCACAACTAATCTTGCCTTGGATTACTAAGCAT
CTCCTGCGATCCCACAGAGGACTGTGGTGGCCACAGGAGCTGAAAGCAGAAGAGTGGGATTTGATGCCAGGCAGTGGAGTGGCCTCAGCC
CCAGATTGTACCTCCTGCCCTGTAGGAGGGGAGGGGGCAAAGCCTTCTGACTTCACCTTTGTTTGACCTATGTATGGAACTTACTTTTAC
TTTTTGCCTTAAATTTTTAATGAAATGCAAATTTTCTGTGATGGGGTTCTCTCTCTCTTTTTTTCGGGGGGTGGAGTCACTAATAAATTT
GCAAATGAAGTTAAAGACAAGGCAACCATCTGGCTTATGCTATATAATACTTCATTTAAAGAAGAAAGGAAAAGCAAATGCACTTGCAGC
TTTTGAGGTCTCAGCAAAAATGGGCATGTGTCTTTTTTGAAGTTTAGAAATATCCTAATCTATTTTTATTTATCTAAAAGTAAGTGTTTT
CCGGCTGATAAGGCTAACCCTACCCAGGAAAGGATTGATAACTAAATAAATTTCCTCTGTTTTCCCATGCATTGAAATTATGTTGGCTGA
GCATGGTGGCTCACACCTGTAATCCTAGCACTTTGGGAGGCCGAGGTGGGCGGATCACTTGAGGTCAGGAGTTGGAGACCAGCCTGGCCA
ACGTGGTGAATCCCCGTCTCTACTGAAAACACAAAAATTAGACGGGCATGGTGGCGCACACCTGTAATCCCAGCTACTTGGGAGGCTGAG
GCAGGAGAATTGCTTGAACCTGGGAGGTGGAGGTTGCAGTGAGCTAAAATTGTGCCACTGCACTCCAGCCTGGGTGACAGAGGAAGACTC
CGTCTCACAAAAAAAAAAAAAGAAAAAAGAAATTATGCCAGCTGTTTAATGTGAGAGAATAGAAAGAATGTTCATGGAATGTACCTGCCC
TGTAAAATGTTTGATCATTTTCATTAATGTTGCAGAGAATCCGACTGCTATTAAGAGAAAGTGAACAAATTAAGAATTTAAAAGACAGGT
TCAGGCATGTCATAAGTGAAAACAAGAAGGCTTAATACAAACTTGTTGGGTTTTGTTCGTGTGTGTGTGTGTGTGTGTGTGTGTGTTTTT
TTTTGGTTCAGCCTATCTAGCCACCTACAAATAATCACATTTCTGTTACCTGAATTTATTTCTCAGCCTGTAAACCTTAGTCACTGTTAC
CTGTTTCTTGCTCAGTGAATATGATCTTGGCACTGTCATCTAGAAAGCAAGATATTTGATTGGTTTTCTGGTTCCTTCGAAGATAATAAT
TCCATATCCAGTTTGACTGATTTTCATACCCCTGAATCAACTAGTTATTTTCATGAAATGGTTTTTGGATATCTCTCCTCTAGTTTGGAG
AAGTAATAATCACAAAGATTAATATTTTGCTTCTAGTACTTACAGTAGAAGAATTTTAAACTGGTACGTCTACTCCTGTTAAATAGAAAG
GGGATTCGTTGTATTATGTGCTTGCTTTTTTTTAATCAATAGAATAAGATTCAATGCATATTTATGTTTTATATTTTCCACTATTCAGGT
ATCATGAAATCACTCTAGAGATGATCAATCAACATCATATTTATACTTTTGGTTAATTATATACTACTCAGGGAAAAAATGAACAAAAAT
AACTACTCATCCTTCAATTTCATTTTCTTGAAACAGTAAGAGTATAATTTGGTATGCCTCAGCTGTCACCATTTTATAAGTGGCTCATTC
TGTTCTTAAAGTAAGTATTTTTATTGGAACTCAGGGTAATTGGGGGAATTTATTTAGCTTCTAAAATATCCGGCAGGATAGAGAAGATTT
ATTTGGCTTCAAAAATGTCTGGTGACCACTTCTCTTATTAGCCACTACTGCCCATTTGCTTCAAAAATATATTTATTGGTCTCCACCATG
TGTGACACACACAGGATTTCCAAACATACCACTTTTGAGAAAAATGTGCAGTAAAAAGGAGGTTTCTAGAAAGTGACAGTAACTCACATT
TAAGCACTAGCTGACCTAGGAGGAGACCTGGATCTTCATTCTGGTTCTGCCTTTCATGAGACTTAAGACTTGGAGGAGCCACCTGTCCTG
TAGACCCCAAGTTCCTCAGCCATAAGCAAACGGGTTAATCCTAAGAGTTCAGGACCAGTTGGGTGTCGTGAACGGAGCCATTAGCAAGGT
CTGTAGGATTCAAGGACTTGGGCACATTCACAGTCCACACTATTGTCATGGTCATTGACTTACTACTTGAGCTCAAAGCCCTGACATTTC
AAAAGGTTGTCATGATAACAGTGAAACCTCTGAATCCCTTAAATCAGAAGGCATGGCAACATACTTTTTCTACTGGCAATAGCTCTTACA
ATGAGTGTTTCATAATGAAATAGTCTCTGCTGAAGAAAACATGTTTTCCTTTTGCTCTCTCTGCTTTGTTGGTTTCTGTGCTGTGTGGAA
TTGGAGAAGATATATGCTCTGAAATATTTTATACAGATTACTGACTACTGGACAGGGTTTACCACTATATAACATCTCAAAGTTATTCAA
GGATATTTAAAGCATATTTAGTTTAGTTACACCTTATTTTAAACCGCAGAAAACAATAGCTTTAAAATTTTTGCCATTAAAATAATTATA
AATTTATACTTTTACTCAAGGACTAGATCACAGTTTTAGGACAAAAATCTCTCCTATTTAAAGTTCATACCTTGTAAGTATTTAGTTTGT
ATATTCATGAACAAATCTGGACATTTATACTTTTTTTGTTTCCTTATCAACTGTTCACAATTATTAGTTAATTGGTCTTAACAGTTCTAC
ATTATAATTGAAAGAAAAATTACTTGAGAAAATAATTGTTTCAGAATAGTGCCTACTATATCTGTGTCAGCTAAAAATTTGTCCAGAGTT
TTAGATATAAGCTAGTATTTTGTGGAGTTTTATCCAGGCGTTAATAGTTCTTCCTGGCTGAAATTTAATATAGGTGCAGAATCCTAAATA
ACACTGTGAGATGTAATCTTAACTGCCCTCAATACCTTATAAAACTGCTGCATTTAACCCAGTGTGCATTTAATGAGTGGCTGGTCGTTG
ATACACTCATCTTAGATGCTGAAATTTCTGTTTTCTCCAGCCCTTGTAAAAGTGGGTTTCTTGATGAACGCGTGCTCCCAATGCTGAAGC
AAAAGATTTGCATTTAAGGAGAGAAATACACCCTGAAATTTGAGTTTGAAAGATTAGAACATAGAGGGTCTCTACAGTGTTTTTCTGCAA
CACCAAGTAGTCAAATCTATTTATAGAAACTCTGATTACAACAGAAATTTTAAAATGAAATTTTCCACATCGGTATTTTGTAGGAAAGCT
CTTATAATCAATGCTTAAGCTGCTTTTTGAGGCTTTTCTTGTACAGAGGTTGCAGCCAATTACATTTTAATTGGTAGGCTGCTGAATAAT
GTTTTTGTATGTTTTAAAATAATATTTATTTTAATAGGTTTTTTAACATTATGCAAATCCCAATAAAGAACTGACACGTTCCATAGGCCA
TTGACTGGGAAATTTTGTGAAACACAGCCTAAATACACAGTTTTTACACCAACTAATTTGTCTTGCCTTTAAAACTGATTATAACTCTTC
TTTAAGTACAACTTTTATAAAGAAAAAATACAACACTAAGACTGTATGTTCTGTAAATTATAGTGTGATGACCCATGCAGAACCGCTGTC
TGAAGCTTACTCAGCGATTCATAGCCATCTCCAGCCATGTTTTATCAAATCACACACTAAAAATAAATGGAAATGCTACAGTGAAAAACC
AAAAGTTACAGAGCAACATAAGTAAAATGACTAGGCAGTTTCTTAGTAACATGTTTGAAATGGGAAAGGTGACTGACTGCCTTTCACCAG
AGTCTTAGCTGTTTCACGTTCACTATTTTAGGTTAATTTTCTTGGGAAATCAATTTGAATATTCCCCCCTGTCCTTTTGCATTAAAGGAC
GAAAATATATGTTGAGAGTTTGACAGACTTTTTAAATATGCCTCTTTCCCAATTTTATGTATTTTTGGTTCTGCGCACACAGATTTATCA
ATGAAGTACATTTGCCTCTGGCTTTATCACAAGGAAAAAGGAATCAAACATTGAACACAAATGTGTTCCAAACCAGTCTTGTCCATCTTG
TCACTTTTATGTGACTGCTCCTCTGAACCAGAAGGGGCACGATAGAAGGCCATAGGAATGAAAGTAAATCATTCAGGTGAAGTGAGAAAT
TCTTCCATATACAGAGTGAAAATGTGTGATTTCATTCCTGCCTTCCTTTAAACGTTGTCTTGATCTCTGCCTAGTAGTAGTTGAGCCCTC
AGTCGCCCAAACATGAGGAGAGACCCAACTCCAGCAGCCAGAATTTAGTATTTACATTTGCCTTCCCAAGTTGAGAATAGAATGTGGTGT
TCTGTGCTTTCTGTTTTTATTATTCCAAAATATTTTTTTAAAGAAGTGTTATTTTTCAACAGATTCATAAATTAGTTCCTGATGTACGGT
AAATTAAAACTCCCACTGTGTCAGTCAAACTGAGATGTGCTCATTTCATAACCACTCATTTCTAGTCTGTCAGAGCTGCACTGGTGGCTT
ATTGCTGGTTTTTAAAGGTGTTTTTAACTTACATGTAACATGTTTAGGACATGTTTTTTTTTTCTAATTTGTGTGTCTTTACAACTGATT

>98517_98517_1_VPS8-MBOAT2_VPS8_chr3_184658031_ENST00000287546_MBOAT2_chr2_9048846_ENST00000305997_length(amino acids)=1438AA_BP=1017
MLLEVNMENEPDHENVEQSLCAKTSEEELNKSFNLEASLSKFSYIDMDKELEFKNDLIDDKEFDIPQVDTPPTLESILNETDDEDESFIL
EDPTLLNIDTIDSHSYDTSSVASSDSGDRTNLKRKKKLPDSFSLHGSVMRHSLLKGISAQIVSAADKVDAGLPTAIAVSSLIAVGTSHGL
ALIFGKYQNQALRLCLGSTSVGGQYGAISALSINNDCSRLLCGFAKGQITMWDLASGKLLRSITDAHPPGTAILHIKFTDDPTLAICNDS
GGSVFELTFKRVMGVRTCESRCLFSGSKGEVCCIEPLHSKPELKDHPITQFSLLAMASLTKILVIGLKPSLKVWMTFPYGRMDPSSVPLL
AWHFVAVQNYVNPMLAFCRGDVVHFLLVKRDESGAIHVTKQKHLHLYYDLINFTWINSRTVVLLDSVEKLHVIDRQTQEELETVEISEVQ
LVYNSSHFKSLATGGNVSQALALVGEKACYQSISSYGGQIFYLGTKSVYVMMLRSWRERVDHLLKQDCLTEALALAWSFHEGKAKAVVGL
SGDASKRKAIVADRMVEILFHYADRALKKCPDQGKIQVMEQHFQDMVPVIVDYCLLLQRKDLLFSQMYDKLSENSVAKGVFLECLEPYIL
SDKLVGITPQVMKDLIVHFQDKKLMENVEALIVHMDITSLDIQQVVLMCWENRLYDAMIYVYNRGMNEFISPMEKLFRVIAPPLNAGKTL
TDEQVVMGNKLLVYISCCLAGRAYPLGDIPEDLVPLVKNQVFEFLIRLHSAEASPEEEIYPYIRTLLHFDTREFLNVLALTFEDFKNDKQ
AVEYQQRIVDILLKVMVENSDFTPSQVGCLFTFLARQLAKPDNTLFVNRTLFDQVLEFLCSPDDDSRHSERQQVLLELLQAGGIVQFEES
RLIRMAEKAEFYQICEFMYEREHQYDKIIDCYLRDPLREEEVFNYIHNILSIPGHSAEEKQSVWQKAMDHIEELVSLKPCKAAELVATHF
SGHIETVIKKLQNQVLLFKFLRSLLDPSYCFVFALGYLTVCQVTRVYIFDYGQYSADFSGPMMIITQKITSLACEIHDGMFRKDEELTSS
QRDLAVRRMPSLLEYLSYNCNFMGILAGPLCSYKDYITFIEGRSYHITQSGENGKEETQYERTEPSPNTAVVQKLLVCGLSLLFHLTICT
TLPVEYNIDEHFQATASWPTKIIYLYISLLAARPKYYFAWTLADAINNAAGFGFRGYDENGAARWDLISNLRIQQIEMSTSFKMFLDNWN
IQTALWLKRVCYERTSFSPTIQTFILSAIWHGVYPGYYLTFLTGVLMTLAARAMRNNFRHYFIEPSQLKLFYDVITWIVTQVAISYTVVP

--------------------------------------------------------------
>98517_98517_2_VPS8-MBOAT2_VPS8_chr3_184658031_ENST00000436792_MBOAT2_chr2_9048846_ENST00000305997_length(transcript)=10425nt_BP=3172nt
AGTGGGTGCGGTCACGTGGGCCGGCGGTCCACGGCCGGAATGGCAGCAAGCTCAGAGATAATCATTCAGGTCTTCGTGAGCTAAGGCCAA
ACAAACAAAAAACACTTGCTTTGATGGACTGAATACTGTTATTAGAAGTAAATATGGAAAATGAACCAGACCATGAAAATGTGGAACAGA
GCCTCTGTGCCAAGACGAGCGAAGAAGAGCTGAATAAGTCTTTCAATCTAGAAGCTTCACTTTCAAAATTCTCTTACATAGATATGGACA
AGGAACTGGAGTTCAAAAATGATCTGATTGATGACAAGGAGTTTGATATTCCTCAAGTTGATACTCCTCCAACACTGGAAAGCATACTAA
ATGAGACTGATGATGAAGATGAGTCTTTTATTCTTGAGGATCCTACATTGTTAAACATTGATACTATTGATTCTCACTCCTATGATACTT
CATCTGTGGCAAGCTCAGATAGTGGTGACAGGACCAACTTAAAAAGGAAGAAGAAATTACCTGATTCTTTTTCACTTCATGGATCAGTTA
TGCGCCATTCACTTTTGAAGGGAATTTCTGCCCAGATAGTGTCTGCAGCTGACAAAGTAGATGCTGGCTTGCCTACAGCAATTGCAGTAT
CCAGTCTGATAGCAGTGGGTACATCTCATGGATTGGCTTTAATATTTGATCAGAATCAAGCTTTGCGACTCTGTCTGGGTAGCACTAGTG
TTGGAGGTCAGTATGGCGCTATCTCTGCCCTCAGTATCAACAATGATTGCTCAAGACTTCTTTGTGGCTTTGCTAAAGGACAGATCACCA
TGTGGGATTTGGCCAGTGGAAAACTTCTAAGATCAATAACAGATGCTCATCCTCCAGGAACAGCAATATTGCATATCAAGTTTACAGATG
ATCCAACTCTTGCAATTTGCAACGACAGCGGAGGCTCTGTTTTTGAATTGACATTTAAGAGAGTGATGGGAGTGAGAACCTGTGAATCTA
GATGTCTGTTCAGTGGTTCCAAGGGTGAAGTCTGCTGTATTGAGCCTCTGCATTCTAAGCCTGAGTTGAAAGATCATCCCATCACACAGT
TTTCATTATTGGCCATGGCATCCTTGACAAAAATACTGGTCATTGGATTGAAACCATCCTTGAAAGTATGGATGACTTTTCCCTATGGCC
GGATGGATCCTTCCAGTGTGCCACTGCTGGCCTGGCACTTTGTAGCAGTACAAAATTACGTGAATCCCATGCTTGCCTTCTGCAGAGGAG
ATGTTGTTCATTTTCTATTGGTAAAGAGAGATGAATCTGGAGCAATACATGTTACTAAGCAAAAGCATCTTCACCTATACTATGACCTCA
TCAACTTTACCTGGATAAATTCACGCACAGTTGTGCTCTTAGACAGCGTAGAGAAGTTGCATGTGATTGATCGGCAAACACAAGAGGAAT
TGGAGACAGTGGAGATCTCAGAAGTTCAGCTGGTCTACAATAGCAGCCATTTCAAATCACTAGCCACTGGAGGAAATGTTAGCCAGGCAC
TGGCTTTGGTTGGAGAGAAGGCTTGTTATCAATCCATCAGTAGCTATGGTGGTCAGATCTTTTATTTGGGGACAAAATCTGTTTATGTGA
TGATGCTGAGGAGCTGGAGAGAGAGAGTGGATCATCTCCTGAAACAAGATTGTCTTACAGAAGCGTTGGCTCTTGCGTGGTCTTTCCATG
AAGGAAAAGCAAAAGCAGTAGTGGGATTATCAGGGGATGCCAGTAAGCGAAAGGCTATTGTTGCAGACCGGATGGTAGAAATCCTATTCC
ATTATGCAGATCGAGCTCTGAAAAAGTGCCCAGACCAAGGAAAAATCCAAGTGATGGAGCAGCATTTTCAGGATATGGTGCCTGTCATAG
TTGATTACTGCCTTCTGCTGCAGCGAAAGGATCTTTTATTTAGTCAGATGTATGATAAATTAAGTGAGAATTCAGTGGCCAAAGGAGTAT
TTTTGGAGTGCCTTGAGCCATATATTTTAAGTGATAAATTGGTGGGAATCACACCCCAAGTAATGAAAGACTTGATTGTTCATTTCCAAG
ATAAAAAATTAATGGAAAATGTGGAAGCGCTCATTGTACATATGGATATCACCAGCCTAGATATTCAGCAGGTAGTTCTCATGTGTTGGG
AAAATCGTTTATATGATGCTATGATCTATGTCTACAACAGAGGCATGAATGAATTTATTAGTCCAATGGAGAAACTTTTCAGAGTCATTG
CTCCTCCTCTGAATGCAGGAAAAACACTAACAGATGAACAAGTTGTTATGGGCAATAAGCTCCTTGTATATATTAGCTGTTGTCTAGCAG
GTCGTGCCTATCCCCTTGGTGACATCCCTGAAGATCTGGTTCCCTTGGTTAAAAACCAGGTTTTTGAATTTCTAATTCGCCTGCATTCAG
CAGAGGCTTCTCCTGAGGAAGAAATCTATCCTTACATTCGGACTTTGCTACATTTTGACACAAGAGAATTTCTAAATGTATTGGCACTGA
CTTTTGAAGATTTTAAAAATGACAAGCAAGCTGTGGAATATCAACAGCGAATTGTGGATATTTTGTTGAAAGTTATGGTGGAGAATTCAG
ACTTTACCCCCTCACAAGTAGGATGTCTCTTTACCTTCCTTGCTCGGCAGCTTGCAAAGCCTGACAACACCTTGTTTGTAAACAGAACAC
TTTTTGATCAGGTCCTTGAATTCCTTTGTAGTCCTGACGATGACTCCCGACACTCTGAAAGACAGCAGGTCCTTTTAGAATTGCTGCAGG
CTGGAGGCATAGTTCAATTTGAAGAGAGTCGACTCATCCGGATGGCAGAAAAAGCTGAGTTCTATCAAATTTGTGAATTTATGTATGAAA
GAGAACACCAATATGATAAAATTATTGATTGCTACTTACGTGACCCTCTGCGAGAGGAAGAAGTCTTTAATTACATTCACAATATCTTAT
CCATTCCCGGACACAGTGCAGAGGAGAAGCAGTCTGTATGGCAGAAAGCAATGGATCATATTGAGGAACTCGTGTCCCTGAAGCCTTGTA
AAGCTGCGGAGCTGGTTGCCACCCACTTTTCTGGACATATTGAAACGGTCATTAAAAAACTTCAGAACCAGGTTTTGCTTTTCAAATTTT
TGAGGAGTCTTCTTGACCCAAGTTACTGCTTTGTGTTTGCTCTGGGATACCTCACAGTGTGCCAAGTTACTCGAGTCTATATCTTTGACT
ATGGACAATATTCTGCTGATTTTTCAGGCCCAATGATGATCATTACTCAGAAGATCACTAGTTTGGCTTGCGAAATTCATGATGGGATGT
TTCGGAAGGATGAAGAACTGACTTCCTCACAGAGGGATTTAGCTGTAAGGCGCATGCCAAGCTTACTGGAGTATTTGAGTTACAACTGTA
ACTTCATGGGGATCCTGGCAGGCCCACTTTGCTCTTACAAAGACTACATTACTTTCATTGAAGGCAGATCATACCATATCACACAATCTG
GTGAAAATGGAAAAGAAGAGACACAGTATGAAAGAACAGAGCCATCTCCAAATACTGCGGTTGTTCAGAAGCTCTTAGTTTGTGGGCTGT
CCTTGTTATTTCACTTGACCATCTGTACAACATTACCTGTGGAGTACAACATTGATGAGCATTTTCAAGCTACAGCTTCGTGGCCAACAA
AGATTATCTATCTGTATATCTCTCTTTTGGCTGCCAGACCCAAATACTATTTTGCATGGACGCTAGCTGATGCCATTAATAATGCTGCAG
GCTTTGGTTTCAGAGGGTATGACGAAAATGGAGCAGCTCGCTGGGACTTAATTTCCAATTTGAGAATTCAACAAATAGAGATGTCAACAA
GTTTCAAGATGTTTCTTGATAATTGGAATATTCAGACAGCTCTTTGGCTCAAAAGGGTGTGTTATGAACGAACCTCCTTCAGTCCAACTA
TCCAGACGTTCATTCTCTCTGCCATTTGGCACGGGGTATACCCAGGATATTATCTAACGTTTCTAACAGGGGTGTTAATGACATTAGCAG
CAAGAGCTATGAGAAATAACTTTAGACATTATTTCATTGAACCTTCCCAACTGAAATTATTTTATGATGTTATAACATGGATAGTAACTC
AAGTAGCAATAAGTTACACAGTTGTGCCATTTGTGCTTCTTTCTATAAAACCATCACTCACGTTTTACAGCTCCTGGTATTATTGCCTGC
ACATTCTTGGTATCTTAGTATTATTGTTGTTGCCAGTGAAAAAAACTCAAAGAAGAAAGAATACACATGAAAACATTCAGCTCTCACAAT
CCAAAAAGTTTGATGAAGGAGAAAATTCTTTGGGACAGAACAGTTTTTCTACAACAAACAATGTTTGCAATCAGAATCAAGAAATAGCCT
CGAGACATTCATCACTAAAGCAGTGATCGGGAAGGCTCTGAGGGCTGTTTTTTTTTTTTGATGTTAACAGAAACCAATCTTAGCACCTTT
TCAAGGGGTTTGAGTTTGTTGGAAAAGCAGTTAACTGGGGGGAAATGGACAGTTATAGATAAGGAATTTCCTGTACACCAGATTGGAAAT
GGAGTGAAACAAGCCCTCCCATGCCATGTCTCCGTGGGCCACGCCTTATGTAAGAATATTTCCATATTTCAGTGGGCACTCCCAACCTCA
GCACTTGTCCGTAGGGTCACACGCGTGCCCTGTTGCTGAATGTATGTTGCGTATCCCAAGGCACTGAAGAGGTGGAAAAATAATCGTGTC
AATCTGGATGATAGAGAGAAATTAACTTTTCCAAATGAATGTCTTGCCTTAAACCCTCTATTTCCTAAAATATTGTTCCTAAATGGTATT
TTCAAGTGTAATATTGTGAGAACGCTACTGCAGTAGTTGATGTTGTGTGCTGTAAAGGATTTTAGGAGGAATTTGAAACAGGATATTTAA
GAGTGTGGATATTTTTAAAATGCAATAAACATCTCAGTATTTGAAGGGTTTTCTTAAAGTATGTCAAATGACTACAATCCATAGTGAAAC
TGTAAACAGTAATGGACGCCAAATTATAGGTAGCTGATTTTGCTGGAGAGTTTAATTACCTTGTGCAGTCAAAGAGCGCTTCCAGAAGGA
ATCTCTTAAAACATAATGAGAGGTTTGGTAATGTGATATTTTAAGCTTATTCTTTTTCTTAAAAGAGAGAGGTGACGAAGGAAGGCAGGA
ATGAAGAAGCACTGCGTGGCCTCCGGTGGAATGCACGGGGCACAGCCGCGACTCTGCAGGCAGCTTCCCCCCCATGCCAGGGCTCTGCGC
CGTCATGTGAGACTTAAAAAAAAAGTTGAATGACTTCGTGATACTTTGGACTTCTAAATTAAATTTATCAGGCATAAATTATGTAGAATT
AGAGGCTTTGAAAATAATACTGGTAGGTTGCTCAAAGGTTTTGAAAGAGAAATCGCTAGGTAGGTTACTATCTGGCTAATCCATTTCTTA
TCCTTGACAATTTAATTCATATTTGGGAAACTTTTAGGGAAATGAAAAATAAAAGTCACTGAGTCTGGGTGACATTTTTTAAGAATAATA
TAAATTCAGTTTCAAACTCTTCTCACATTAAAATTTTGCTGTGAACTCTTACTAAAATGAGTTTTAGGTTCTGTAAGTGGAAAAATGTGC
TTTTATTTTATGGGCCATTTTTACCACAACTAATCTTGCCTTGGATTACTAAGCATCTCCTGCGATCCCACAGAGGACTGTGGTGGCCAC
AGGAGCTGAAAGCAGAAGAGTGGGATTTGATGCCAGGCAGTGGAGTGGCCTCAGCCCCAGATTGTACCTCCTGCCCTGTAGGAGGGGAGG
GGGCAAAGCCTTCTGACTTCACCTTTGTTTGACCTATGTATGGAACTTACTTTTACTTTTTGCCTTAAATTTTTAATGAAATGCAAATTT
TCTGTGATGGGGTTCTCTCTCTCTTTTTTTCGGGGGGTGGAGTCACTAATAAATTTGCAAATGAAGTTAAAGACAAGGCAACCATCTGGC
TTATGCTATATAATACTTCATTTAAAGAAGAAAGGAAAAGCAAATGCACTTGCAGCTTTTGAGGTCTCAGCAAAAATGGGCATGTGTCTT
TTTTGAAGTTTAGAAATATCCTAATCTATTTTTATTTATCTAAAAGTAAGTGTTTTCCGGCTGATAAGGCTAACCCTACCCAGGAAAGGA
TTGATAACTAAATAAATTTCCTCTGTTTTCCCATGCATTGAAATTATGTTGGCTGAGCATGGTGGCTCACACCTGTAATCCTAGCACTTT
GGGAGGCCGAGGTGGGCGGATCACTTGAGGTCAGGAGTTGGAGACCAGCCTGGCCAACGTGGTGAATCCCCGTCTCTACTGAAAACACAA
AAATTAGACGGGCATGGTGGCGCACACCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATTGCTTGAACCTGGGAGGTGGAGGT
TGCAGTGAGCTAAAATTGTGCCACTGCACTCCAGCCTGGGTGACAGAGGAAGACTCCGTCTCACAAAAAAAAAAAAAGAAAAAAGAAATT
ATGCCAGCTGTTTAATGTGAGAGAATAGAAAGAATGTTCATGGAATGTACCTGCCCTGTAAAATGTTTGATCATTTTCATTAATGTTGCA
GAGAATCCGACTGCTATTAAGAGAAAGTGAACAAATTAAGAATTTAAAAGACAGGTTCAGGCATGTCATAAGTGAAAACAAGAAGGCTTA
ATACAAACTTGTTGGGTTTTGTTCGTGTGTGTGTGTGTGTGTGTGTGTGTGTTTTTTTTTGGTTCAGCCTATCTAGCCACCTACAAATAA
TCACATTTCTGTTACCTGAATTTATTTCTCAGCCTGTAAACCTTAGTCACTGTTACCTGTTTCTTGCTCAGTGAATATGATCTTGGCACT
GTCATCTAGAAAGCAAGATATTTGATTGGTTTTCTGGTTCCTTCGAAGATAATAATTCCATATCCAGTTTGACTGATTTTCATACCCCTG
AATCAACTAGTTATTTTCATGAAATGGTTTTTGGATATCTCTCCTCTAGTTTGGAGAAGTAATAATCACAAAGATTAATATTTTGCTTCT
AGTACTTACAGTAGAAGAATTTTAAACTGGTACGTCTACTCCTGTTAAATAGAAAGGGGATTCGTTGTATTATGTGCTTGCTTTTTTTTA
ATCAATAGAATAAGATTCAATGCATATTTATGTTTTATATTTTCCACTATTCAGGTATCATGAAATCACTCTAGAGATGATCAATCAACA
TCATATTTATACTTTTGGTTAATTATATACTACTCAGGGAAAAAATGAACAAAAATAACTACTCATCCTTCAATTTCATTTTCTTGAAAC
AGTAAGAGTATAATTTGGTATGCCTCAGCTGTCACCATTTTATAAGTGGCTCATTCTGTTCTTAAAGTAAGTATTTTTATTGGAACTCAG
GGTAATTGGGGGAATTTATTTAGCTTCTAAAATATCCGGCAGGATAGAGAAGATTTATTTGGCTTCAAAAATGTCTGGTGACCACTTCTC
TTATTAGCCACTACTGCCCATTTGCTTCAAAAATATATTTATTGGTCTCCACCATGTGTGACACACACAGGATTTCCAAACATACCACTT
TTGAGAAAAATGTGCAGTAAAAAGGAGGTTTCTAGAAAGTGACAGTAACTCACATTTAAGCACTAGCTGACCTAGGAGGAGACCTGGATC
TTCATTCTGGTTCTGCCTTTCATGAGACTTAAGACTTGGAGGAGCCACCTGTCCTGTAGACCCCAAGTTCCTCAGCCATAAGCAAACGGG
TTAATCCTAAGAGTTCAGGACCAGTTGGGTGTCGTGAACGGAGCCATTAGCAAGGTCTGTAGGATTCAAGGACTTGGGCACATTCACAGT
CCACACTATTGTCATGGTCATTGACTTACTACTTGAGCTCAAAGCCCTGACATTTCAAAAGGTTGTCATGATAACAGTGAAACCTCTGAA
TCCCTTAAATCAGAAGGCATGGCAACATACTTTTTCTACTGGCAATAGCTCTTACAATGAGTGTTTCATAATGAAATAGTCTCTGCTGAA
GAAAACATGTTTTCCTTTTGCTCTCTCTGCTTTGTTGGTTTCTGTGCTGTGTGGAATTGGAGAAGATATATGCTCTGAAATATTTTATAC
AGATTACTGACTACTGGACAGGGTTTACCACTATATAACATCTCAAAGTTATTCAAGGATATTTAAAGCATATTTAGTTTAGTTACACCT
TATTTTAAACCGCAGAAAACAATAGCTTTAAAATTTTTGCCATTAAAATAATTATAAATTTATACTTTTACTCAAGGACTAGATCACAGT
TTTAGGACAAAAATCTCTCCTATTTAAAGTTCATACCTTGTAAGTATTTAGTTTGTATATTCATGAACAAATCTGGACATTTATACTTTT
TTTGTTTCCTTATCAACTGTTCACAATTATTAGTTAATTGGTCTTAACAGTTCTACATTATAATTGAAAGAAAAATTACTTGAGAAAATA
ATTGTTTCAGAATAGTGCCTACTATATCTGTGTCAGCTAAAAATTTGTCCAGAGTTTTAGATATAAGCTAGTATTTTGTGGAGTTTTATC
CAGGCGTTAATAGTTCTTCCTGGCTGAAATTTAATATAGGTGCAGAATCCTAAATAACACTGTGAGATGTAATCTTAACTGCCCTCAATA
CCTTATAAAACTGCTGCATTTAACCCAGTGTGCATTTAATGAGTGGCTGGTCGTTGATACACTCATCTTAGATGCTGAAATTTCTGTTTT
CTCCAGCCCTTGTAAAAGTGGGTTTCTTGATGAACGCGTGCTCCCAATGCTGAAGCAAAAGATTTGCATTTAAGGAGAGAAATACACCCT
GAAATTTGAGTTTGAAAGATTAGAACATAGAGGGTCTCTACAGTGTTTTTCTGCAACACCAAGTAGTCAAATCTATTTATAGAAACTCTG
ATTACAACAGAAATTTTAAAATGAAATTTTCCACATCGGTATTTTGTAGGAAAGCTCTTATAATCAATGCTTAAGCTGCTTTTTGAGGCT
TTTCTTGTACAGAGGTTGCAGCCAATTACATTTTAATTGGTAGGCTGCTGAATAATGTTTTTGTATGTTTTAAAATAATATTTATTTTAA
TAGGTTTTTTAACATTATGCAAATCCCAATAAAGAACTGACACGTTCCATAGGCCATTGACTGGGAAATTTTGTGAAACACAGCCTAAAT
ACACAGTTTTTACACCAACTAATTTGTCTTGCCTTTAAAACTGATTATAACTCTTCTTTAAGTACAACTTTTATAAAGAAAAAATACAAC
ACTAAGACTGTATGTTCTGTAAATTATAGTGTGATGACCCATGCAGAACCGCTGTCTGAAGCTTACTCAGCGATTCATAGCCATCTCCAG
CCATGTTTTATCAAATCACACACTAAAAATAAATGGAAATGCTACAGTGAAAAACCAAAAGTTACAGAGCAACATAAGTAAAATGACTAG
GCAGTTTCTTAGTAACATGTTTGAAATGGGAAAGGTGACTGACTGCCTTTCACCAGAGTCTTAGCTGTTTCACGTTCACTATTTTAGGTT
AATTTTCTTGGGAAATCAATTTGAATATTCCCCCCTGTCCTTTTGCATTAAAGGACGAAAATATATGTTGAGAGTTTGACAGACTTTTTA
AATATGCCTCTTTCCCAATTTTATGTATTTTTGGTTCTGCGCACACAGATTTATCAATGAAGTACATTTGCCTCTGGCTTTATCACAAGG
AAAAAGGAATCAAACATTGAACACAAATGTGTTCCAAACCAGTCTTGTCCATCTTGTCACTTTTATGTGACTGCTCCTCTGAACCAGAAG
GGGCACGATAGAAGGCCATAGGAATGAAAGTAAATCATTCAGGTGAAGTGAGAAATTCTTCCATATACAGAGTGAAAATGTGTGATTTCA
TTCCTGCCTTCCTTTAAACGTTGTCTTGATCTCTGCCTAGTAGTAGTTGAGCCCTCAGTCGCCCAAACATGAGGAGAGACCCAACTCCAG
CAGCCAGAATTTAGTATTTACATTTGCCTTCCCAAGTTGAGAATAGAATGTGGTGTTCTGTGCTTTCTGTTTTTATTATTCCAAAATATT
TTTTTAAAGAAGTGTTATTTTTCAACAGATTCATAAATTAGTTCCTGATGTACGGTAAATTAAAACTCCCACTGTGTCAGTCAAACTGAG
ATGTGCTCATTTCATAACCACTCATTTCTAGTCTGTCAGAGCTGCACTGGTGGCTTATTGCTGGTTTTTAAAGGTGTTTTTAACTTACAT

>98517_98517_2_VPS8-MBOAT2_VPS8_chr3_184658031_ENST00000436792_MBOAT2_chr2_9048846_ENST00000305997_length(amino acids)=1436AA_BP=1015
MLLEVNMENEPDHENVEQSLCAKTSEEELNKSFNLEASLSKFSYIDMDKELEFKNDLIDDKEFDIPQVDTPPTLESILNETDDEDESFIL
EDPTLLNIDTIDSHSYDTSSVASSDSGDRTNLKRKKKLPDSFSLHGSVMRHSLLKGISAQIVSAADKVDAGLPTAIAVSSLIAVGTSHGL
ALIFDQNQALRLCLGSTSVGGQYGAISALSINNDCSRLLCGFAKGQITMWDLASGKLLRSITDAHPPGTAILHIKFTDDPTLAICNDSGG
SVFELTFKRVMGVRTCESRCLFSGSKGEVCCIEPLHSKPELKDHPITQFSLLAMASLTKILVIGLKPSLKVWMTFPYGRMDPSSVPLLAW
HFVAVQNYVNPMLAFCRGDVVHFLLVKRDESGAIHVTKQKHLHLYYDLINFTWINSRTVVLLDSVEKLHVIDRQTQEELETVEISEVQLV
YNSSHFKSLATGGNVSQALALVGEKACYQSISSYGGQIFYLGTKSVYVMMLRSWRERVDHLLKQDCLTEALALAWSFHEGKAKAVVGLSG
DASKRKAIVADRMVEILFHYADRALKKCPDQGKIQVMEQHFQDMVPVIVDYCLLLQRKDLLFSQMYDKLSENSVAKGVFLECLEPYILSD
KLVGITPQVMKDLIVHFQDKKLMENVEALIVHMDITSLDIQQVVLMCWENRLYDAMIYVYNRGMNEFISPMEKLFRVIAPPLNAGKTLTD
EQVVMGNKLLVYISCCLAGRAYPLGDIPEDLVPLVKNQVFEFLIRLHSAEASPEEEIYPYIRTLLHFDTREFLNVLALTFEDFKNDKQAV
EYQQRIVDILLKVMVENSDFTPSQVGCLFTFLARQLAKPDNTLFVNRTLFDQVLEFLCSPDDDSRHSERQQVLLELLQAGGIVQFEESRL
IRMAEKAEFYQICEFMYEREHQYDKIIDCYLRDPLREEEVFNYIHNILSIPGHSAEEKQSVWQKAMDHIEELVSLKPCKAAELVATHFSG
HIETVIKKLQNQVLLFKFLRSLLDPSYCFVFALGYLTVCQVTRVYIFDYGQYSADFSGPMMIITQKITSLACEIHDGMFRKDEELTSSQR
DLAVRRMPSLLEYLSYNCNFMGILAGPLCSYKDYITFIEGRSYHITQSGENGKEETQYERTEPSPNTAVVQKLLVCGLSLLFHLTICTTL
PVEYNIDEHFQATASWPTKIIYLYISLLAARPKYYFAWTLADAINNAAGFGFRGYDENGAARWDLISNLRIQQIEMSTSFKMFLDNWNIQ
TALWLKRVCYERTSFSPTIQTFILSAIWHGVYPGYYLTFLTGVLMTLAARAMRNNFRHYFIEPSQLKLFYDVITWIVTQVAISYTVVPFV

--------------------------------------------------------------
>98517_98517_3_VPS8-MBOAT2_VPS8_chr3_184658031_ENST00000437079_MBOAT2_chr2_9048846_ENST00000305997_length(transcript)=10459nt_BP=3206nt
AGGTAGTGCGCGTGCGTGAGGCTAGAGCAGTGGGTGCGGTCACGTGGGCCGGCGGTCCACGGCCGGAATGGCAGCAAGCTCAGAGATAAT
CATTCAGGTCTTCGTGAGCTAAGGCCAAACAAACAAAAAACACTTGCTTTGATGGACTGAATACTGTTATTAGAAGTAAATATGGAAAAT
GAACCAGACCATGAAAATGTGGAACAGAGCCTCTGTGCCAAGACGAGCGAAGAAGAGCTGAATAAGTCTTTCAATCTAGAAGCTTCACTT
TCAAAATTCTCTTACATAGATATGGACAAGGAACTGGAGTTCAAAAATGATCTGATTGATGACAAGGAGTTTGATATTCCTCAAGTTGAT
ACTCCTCCAACACTGGAAAGCATACTAAATGAGACTGATGATGAAGATGAGTCTTTTATTCTTGAGGATCCTACATTGTTAAACATTGAT
ACTATTGATTCTCACTCCTATGATACTTCATCTGTGGCAAGCTCAGATAGTGGTGACAGGACCAACTTAAAAAGGAAGAAGAAATTACCT
GATTCTTTTTCACTTCATGGATCAGTTATGCGCCATTCACTTTTGAAGGGAATTTCTGCCCAGATAGTGTCTGCAGCTGACAAAGTAGAT
GCTGGCTTGCCTACAGCAATTGCAGTATCCAGTCTGATAGCAGTGGGTACATCTCATGGATTGGCTTTAATATTTGGAAAAGATCAGAAT
CAAGCTTTGCGACTCTGTCTGGGTAGCACTAGTGTTGGAGGTCAGTATGGCGCTATCTCTGCCCTCAGTATCAACAATGATTGCTCAAGA
CTTCTTTGTGGCTTTGCTAAAGGACAGATCACCATGTGGGATTTGGCCAGTGGAAAACTTCTAAGATCAATAACAGATGCTCATCCTCCA
GGAACAGCAATATTGCATATCAAGTTTACAGATGATCCAACTCTTGCAATTTGCAACGACAGCGGAGGCTCTGTTTTTGAATTGACATTT
AAGAGAGTGATGGGAGTGAGAACCTGTGAATCTAGATGTCTGTTCAGTGGTTCCAAGGGTGAAGTCTGCTGTATTGAGCCTCTGCATTCT
AAGCCTGAGTTGAAAGATCATCCCATCACACAGTTTTCATTATTGGCCATGGCATCCTTGACAAAAATACTGGTCATTGGATTGAAACCA
TCCTTGAAAGTATGGATGACTTTTCCCTATGGCCGGATGGATCCTTCCAGTGTGCCACTGCTGGCCTGGCACTTTGTAGCAGTACAAAAT
TACGTGAATCCCATGCTTGCCTTCTGCAGAGGAGATGTTGTTCATTTTCTATTGGTAAAGAGAGATGAATCTGGAGCAATACATGTTACT
AAGCAAAAGCATCTTCACCTATACTATGACCTCATCAACTTTACCTGGATAAATTCACGCACAGTTGTGCTCTTAGACAGCGTAGAGAAG
TTGCATGTGATTGATCGGCAAACACAAGAGGAATTGGAGACAGTGGAGATCTCAGAAGTTCAGCTGGTCTACAATAGCAGCCATTTCAAA
TCACTAGCCACTGGAGGAAATGTTAGCCAGGCACTGGCTTTGGTTGGAGAGAAGGCTTGTTATCAATCCATCAGTAGCTATGGTGGTCAG
ATCTTTTATTTGGGGACAAAATCTGTTTATGTGATGATGCTGAGGAGCTGGAGAGAGAGAGTGGATCATCTCCTGAAACAAGATTGTCTT
ACAGAAGCGTTGGCTCTTGCGTGGTCTTTCCATGAAGGAAAAGCAAAAGCAGTAGTGGGATTATCAGGGGATGCCAGTAAGCGAAAGGCT
ATTGTTGCAGACCGGATGGTAGAAATCCTATTCCATTATGCAGATCGAGCTCTGAAAAAGTGCCCAGACCAAGGAAAAATCCAAGTGATG
GAGCAGCATTTTCAGGATATGGTGCCTGTCATAGTTGATTACTGCCTTCTGCTGCAGCGAAAGGATCTTTTATTTAGTCAGATGTATGAT
AAATTAAGTGAGAATTCAGTGGCCAAAGGAGTATTTTTGGAGTGCCTTGAGCCATATATTTTAAGTGATAAATTGGTGGGAATCACACCC
CAAGTAATGAAAGACTTGATTGTTCATTTCCAAGATAAAAAATTAATGGAAAATGTGGAAGCGCTCATTGTACATATGGATATCACCAGC
CTAGATATTCAGCAGGTAGTTCTCATGTGTTGGGAAAATCGTTTATATGATGCTATGATCTATGTCTACAACAGAGGCATGAATGAATTT
ATTAGTCCAATGGAGAAACTTTTCAGAGTCATTGCTCCTCCTCTGAATGCAGGAAAAACACTAACAGATGAACAAGTTGTTATGGGCAAT
AAGCTCCTTGTATATATTAGCTGTTGTCTAGCAGGTCGTGCCTATCCCCTTGGTGACATCCCTGAAGATCTGGTTCCCTTGGTTAAAAAC
CAGGTTTTTGAATTTCTAATTCGCCTGCATTCAGCAGAGGCTTCTCCTGAGGAAGAAATCTATCCTTACATTCGGACTTTGCTACATTTT
GACACAAGAGAATTTCTAAATGTATTGGCACTGACTTTTGAAGATTTTAAAAATGACAAGCAAGCTGTGGAATATCAACAGCGAATTGTG
GATATTTTGTTGAAAGTTATGGTGGAGAATTCAGACTTTACCCCCTCACAAGTAGGATGTCTCTTTACCTTCCTTGCTCGGCAGCTTGCA
AAGCCTGACAACACCTTGTTTGTAAACAGAACACTTTTTGATCAGGTCCTTGAATTCCTTTGTAGTCCTGACGATGACTCCCGACACTCT
GAAAGACAGCAGGTCCTTTTAGAATTGCTGCAGGCTGGAGGCATAGTTCAATTTGAAGAGAGTCGACTCATCCGGATGGCAGAAAAAGCT
GAGTTCTATCAAATTTGTGAATTTATGTATGAAAGAGAACACCAATATGATAAAATTATTGATTGCTACTTACGTGACCCTCTGCGAGAG
GAAGAAGTCTTTAATTACATTCACAATATCTTATCCATTCCCGGACACAGTGCAGAGGAGAAGCAGTCTGTATGGCAGAAAGCAATGGAT
CATATTGAGGAACTCGTGTCCCTGAAGCCTTGTAAAGCTGCGGAGCTGGTTGCCACCCACTTTTCTGGACATATTGAAACGGTCATTAAA
AAACTTCAGAACCAGGTTTTGCTTTTCAAATTTTTGAGGAGTCTTCTTGACCCAAGTTACTGCTTTGTGTTTGCTCTGGGATACCTCACA
GTGTGCCAAGTTACTCGAGTCTATATCTTTGACTATGGACAATATTCTGCTGATTTTTCAGGCCCAATGATGATCATTACTCAGAAGATC
ACTAGTTTGGCTTGCGAAATTCATGATGGGATGTTTCGGAAGGATGAAGAACTGACTTCCTCACAGAGGGATTTAGCTGTAAGGCGCATG
CCAAGCTTACTGGAGTATTTGAGTTACAACTGTAACTTCATGGGGATCCTGGCAGGCCCACTTTGCTCTTACAAAGACTACATTACTTTC
ATTGAAGGCAGATCATACCATATCACACAATCTGGTGAAAATGGAAAAGAAGAGACACAGTATGAAAGAACAGAGCCATCTCCAAATACT
GCGGTTGTTCAGAAGCTCTTAGTTTGTGGGCTGTCCTTGTTATTTCACTTGACCATCTGTACAACATTACCTGTGGAGTACAACATTGAT
GAGCATTTTCAAGCTACAGCTTCGTGGCCAACAAAGATTATCTATCTGTATATCTCTCTTTTGGCTGCCAGACCCAAATACTATTTTGCA
TGGACGCTAGCTGATGCCATTAATAATGCTGCAGGCTTTGGTTTCAGAGGGTATGACGAAAATGGAGCAGCTCGCTGGGACTTAATTTCC
AATTTGAGAATTCAACAAATAGAGATGTCAACAAGTTTCAAGATGTTTCTTGATAATTGGAATATTCAGACAGCTCTTTGGCTCAAAAGG
GTGTGTTATGAACGAACCTCCTTCAGTCCAACTATCCAGACGTTCATTCTCTCTGCCATTTGGCACGGGGTATACCCAGGATATTATCTA
ACGTTTCTAACAGGGGTGTTAATGACATTAGCAGCAAGAGCTATGAGAAATAACTTTAGACATTATTTCATTGAACCTTCCCAACTGAAA
TTATTTTATGATGTTATAACATGGATAGTAACTCAAGTAGCAATAAGTTACACAGTTGTGCCATTTGTGCTTCTTTCTATAAAACCATCA
CTCACGTTTTACAGCTCCTGGTATTATTGCCTGCACATTCTTGGTATCTTAGTATTATTGTTGTTGCCAGTGAAAAAAACTCAAAGAAGA
AAGAATACACATGAAAACATTCAGCTCTCACAATCCAAAAAGTTTGATGAAGGAGAAAATTCTTTGGGACAGAACAGTTTTTCTACAACA
AACAATGTTTGCAATCAGAATCAAGAAATAGCCTCGAGACATTCATCACTAAAGCAGTGATCGGGAAGGCTCTGAGGGCTGTTTTTTTTT
TTTGATGTTAACAGAAACCAATCTTAGCACCTTTTCAAGGGGTTTGAGTTTGTTGGAAAAGCAGTTAACTGGGGGGAAATGGACAGTTAT
AGATAAGGAATTTCCTGTACACCAGATTGGAAATGGAGTGAAACAAGCCCTCCCATGCCATGTCTCCGTGGGCCACGCCTTATGTAAGAA
TATTTCCATATTTCAGTGGGCACTCCCAACCTCAGCACTTGTCCGTAGGGTCACACGCGTGCCCTGTTGCTGAATGTATGTTGCGTATCC
CAAGGCACTGAAGAGGTGGAAAAATAATCGTGTCAATCTGGATGATAGAGAGAAATTAACTTTTCCAAATGAATGTCTTGCCTTAAACCC
TCTATTTCCTAAAATATTGTTCCTAAATGGTATTTTCAAGTGTAATATTGTGAGAACGCTACTGCAGTAGTTGATGTTGTGTGCTGTAAA
GGATTTTAGGAGGAATTTGAAACAGGATATTTAAGAGTGTGGATATTTTTAAAATGCAATAAACATCTCAGTATTTGAAGGGTTTTCTTA
AAGTATGTCAAATGACTACAATCCATAGTGAAACTGTAAACAGTAATGGACGCCAAATTATAGGTAGCTGATTTTGCTGGAGAGTTTAAT
TACCTTGTGCAGTCAAAGAGCGCTTCCAGAAGGAATCTCTTAAAACATAATGAGAGGTTTGGTAATGTGATATTTTAAGCTTATTCTTTT
TCTTAAAAGAGAGAGGTGACGAAGGAAGGCAGGAATGAAGAAGCACTGCGTGGCCTCCGGTGGAATGCACGGGGCACAGCCGCGACTCTG
CAGGCAGCTTCCCCCCCATGCCAGGGCTCTGCGCCGTCATGTGAGACTTAAAAAAAAAGTTGAATGACTTCGTGATACTTTGGACTTCTA
AATTAAATTTATCAGGCATAAATTATGTAGAATTAGAGGCTTTGAAAATAATACTGGTAGGTTGCTCAAAGGTTTTGAAAGAGAAATCGC
TAGGTAGGTTACTATCTGGCTAATCCATTTCTTATCCTTGACAATTTAATTCATATTTGGGAAACTTTTAGGGAAATGAAAAATAAAAGT
CACTGAGTCTGGGTGACATTTTTTAAGAATAATATAAATTCAGTTTCAAACTCTTCTCACATTAAAATTTTGCTGTGAACTCTTACTAAA
ATGAGTTTTAGGTTCTGTAAGTGGAAAAATGTGCTTTTATTTTATGGGCCATTTTTACCACAACTAATCTTGCCTTGGATTACTAAGCAT
CTCCTGCGATCCCACAGAGGACTGTGGTGGCCACAGGAGCTGAAAGCAGAAGAGTGGGATTTGATGCCAGGCAGTGGAGTGGCCTCAGCC
CCAGATTGTACCTCCTGCCCTGTAGGAGGGGAGGGGGCAAAGCCTTCTGACTTCACCTTTGTTTGACCTATGTATGGAACTTACTTTTAC
TTTTTGCCTTAAATTTTTAATGAAATGCAAATTTTCTGTGATGGGGTTCTCTCTCTCTTTTTTTCGGGGGGTGGAGTCACTAATAAATTT
GCAAATGAAGTTAAAGACAAGGCAACCATCTGGCTTATGCTATATAATACTTCATTTAAAGAAGAAAGGAAAAGCAAATGCACTTGCAGC
TTTTGAGGTCTCAGCAAAAATGGGCATGTGTCTTTTTTGAAGTTTAGAAATATCCTAATCTATTTTTATTTATCTAAAAGTAAGTGTTTT
CCGGCTGATAAGGCTAACCCTACCCAGGAAAGGATTGATAACTAAATAAATTTCCTCTGTTTTCCCATGCATTGAAATTATGTTGGCTGA
GCATGGTGGCTCACACCTGTAATCCTAGCACTTTGGGAGGCCGAGGTGGGCGGATCACTTGAGGTCAGGAGTTGGAGACCAGCCTGGCCA
ACGTGGTGAATCCCCGTCTCTACTGAAAACACAAAAATTAGACGGGCATGGTGGCGCACACCTGTAATCCCAGCTACTTGGGAGGCTGAG
GCAGGAGAATTGCTTGAACCTGGGAGGTGGAGGTTGCAGTGAGCTAAAATTGTGCCACTGCACTCCAGCCTGGGTGACAGAGGAAGACTC
CGTCTCACAAAAAAAAAAAAAGAAAAAAGAAATTATGCCAGCTGTTTAATGTGAGAGAATAGAAAGAATGTTCATGGAATGTACCTGCCC
TGTAAAATGTTTGATCATTTTCATTAATGTTGCAGAGAATCCGACTGCTATTAAGAGAAAGTGAACAAATTAAGAATTTAAAAGACAGGT
TCAGGCATGTCATAAGTGAAAACAAGAAGGCTTAATACAAACTTGTTGGGTTTTGTTCGTGTGTGTGTGTGTGTGTGTGTGTGTGTTTTT
TTTTGGTTCAGCCTATCTAGCCACCTACAAATAATCACATTTCTGTTACCTGAATTTATTTCTCAGCCTGTAAACCTTAGTCACTGTTAC
CTGTTTCTTGCTCAGTGAATATGATCTTGGCACTGTCATCTAGAAAGCAAGATATTTGATTGGTTTTCTGGTTCCTTCGAAGATAATAAT
TCCATATCCAGTTTGACTGATTTTCATACCCCTGAATCAACTAGTTATTTTCATGAAATGGTTTTTGGATATCTCTCCTCTAGTTTGGAG
AAGTAATAATCACAAAGATTAATATTTTGCTTCTAGTACTTACAGTAGAAGAATTTTAAACTGGTACGTCTACTCCTGTTAAATAGAAAG
GGGATTCGTTGTATTATGTGCTTGCTTTTTTTTAATCAATAGAATAAGATTCAATGCATATTTATGTTTTATATTTTCCACTATTCAGGT
ATCATGAAATCACTCTAGAGATGATCAATCAACATCATATTTATACTTTTGGTTAATTATATACTACTCAGGGAAAAAATGAACAAAAAT
AACTACTCATCCTTCAATTTCATTTTCTTGAAACAGTAAGAGTATAATTTGGTATGCCTCAGCTGTCACCATTTTATAAGTGGCTCATTC
TGTTCTTAAAGTAAGTATTTTTATTGGAACTCAGGGTAATTGGGGGAATTTATTTAGCTTCTAAAATATCCGGCAGGATAGAGAAGATTT
ATTTGGCTTCAAAAATGTCTGGTGACCACTTCTCTTATTAGCCACTACTGCCCATTTGCTTCAAAAATATATTTATTGGTCTCCACCATG
TGTGACACACACAGGATTTCCAAACATACCACTTTTGAGAAAAATGTGCAGTAAAAAGGAGGTTTCTAGAAAGTGACAGTAACTCACATT
TAAGCACTAGCTGACCTAGGAGGAGACCTGGATCTTCATTCTGGTTCTGCCTTTCATGAGACTTAAGACTTGGAGGAGCCACCTGTCCTG
TAGACCCCAAGTTCCTCAGCCATAAGCAAACGGGTTAATCCTAAGAGTTCAGGACCAGTTGGGTGTCGTGAACGGAGCCATTAGCAAGGT
CTGTAGGATTCAAGGACTTGGGCACATTCACAGTCCACACTATTGTCATGGTCATTGACTTACTACTTGAGCTCAAAGCCCTGACATTTC
AAAAGGTTGTCATGATAACAGTGAAACCTCTGAATCCCTTAAATCAGAAGGCATGGCAACATACTTTTTCTACTGGCAATAGCTCTTACA
ATGAGTGTTTCATAATGAAATAGTCTCTGCTGAAGAAAACATGTTTTCCTTTTGCTCTCTCTGCTTTGTTGGTTTCTGTGCTGTGTGGAA
TTGGAGAAGATATATGCTCTGAAATATTTTATACAGATTACTGACTACTGGACAGGGTTTACCACTATATAACATCTCAAAGTTATTCAA
GGATATTTAAAGCATATTTAGTTTAGTTACACCTTATTTTAAACCGCAGAAAACAATAGCTTTAAAATTTTTGCCATTAAAATAATTATA
AATTTATACTTTTACTCAAGGACTAGATCACAGTTTTAGGACAAAAATCTCTCCTATTTAAAGTTCATACCTTGTAAGTATTTAGTTTGT
ATATTCATGAACAAATCTGGACATTTATACTTTTTTTGTTTCCTTATCAACTGTTCACAATTATTAGTTAATTGGTCTTAACAGTTCTAC
ATTATAATTGAAAGAAAAATTACTTGAGAAAATAATTGTTTCAGAATAGTGCCTACTATATCTGTGTCAGCTAAAAATTTGTCCAGAGTT
TTAGATATAAGCTAGTATTTTGTGGAGTTTTATCCAGGCGTTAATAGTTCTTCCTGGCTGAAATTTAATATAGGTGCAGAATCCTAAATA
ACACTGTGAGATGTAATCTTAACTGCCCTCAATACCTTATAAAACTGCTGCATTTAACCCAGTGTGCATTTAATGAGTGGCTGGTCGTTG
ATACACTCATCTTAGATGCTGAAATTTCTGTTTTCTCCAGCCCTTGTAAAAGTGGGTTTCTTGATGAACGCGTGCTCCCAATGCTGAAGC
AAAAGATTTGCATTTAAGGAGAGAAATACACCCTGAAATTTGAGTTTGAAAGATTAGAACATAGAGGGTCTCTACAGTGTTTTTCTGCAA
CACCAAGTAGTCAAATCTATTTATAGAAACTCTGATTACAACAGAAATTTTAAAATGAAATTTTCCACATCGGTATTTTGTAGGAAAGCT
CTTATAATCAATGCTTAAGCTGCTTTTTGAGGCTTTTCTTGTACAGAGGTTGCAGCCAATTACATTTTAATTGGTAGGCTGCTGAATAAT
GTTTTTGTATGTTTTAAAATAATATTTATTTTAATAGGTTTTTTAACATTATGCAAATCCCAATAAAGAACTGACACGTTCCATAGGCCA
TTGACTGGGAAATTTTGTGAAACACAGCCTAAATACACAGTTTTTACACCAACTAATTTGTCTTGCCTTTAAAACTGATTATAACTCTTC
TTTAAGTACAACTTTTATAAAGAAAAAATACAACACTAAGACTGTATGTTCTGTAAATTATAGTGTGATGACCCATGCAGAACCGCTGTC
TGAAGCTTACTCAGCGATTCATAGCCATCTCCAGCCATGTTTTATCAAATCACACACTAAAAATAAATGGAAATGCTACAGTGAAAAACC
AAAAGTTACAGAGCAACATAAGTAAAATGACTAGGCAGTTTCTTAGTAACATGTTTGAAATGGGAAAGGTGACTGACTGCCTTTCACCAG
AGTCTTAGCTGTTTCACGTTCACTATTTTAGGTTAATTTTCTTGGGAAATCAATTTGAATATTCCCCCCTGTCCTTTTGCATTAAAGGAC
GAAAATATATGTTGAGAGTTTGACAGACTTTTTAAATATGCCTCTTTCCCAATTTTATGTATTTTTGGTTCTGCGCACACAGATTTATCA
ATGAAGTACATTTGCCTCTGGCTTTATCACAAGGAAAAAGGAATCAAACATTGAACACAAATGTGTTCCAAACCAGTCTTGTCCATCTTG
TCACTTTTATGTGACTGCTCCTCTGAACCAGAAGGGGCACGATAGAAGGCCATAGGAATGAAAGTAAATCATTCAGGTGAAGTGAGAAAT
TCTTCCATATACAGAGTGAAAATGTGTGATTTCATTCCTGCCTTCCTTTAAACGTTGTCTTGATCTCTGCCTAGTAGTAGTTGAGCCCTC
AGTCGCCCAAACATGAGGAGAGACCCAACTCCAGCAGCCAGAATTTAGTATTTACATTTGCCTTCCCAAGTTGAGAATAGAATGTGGTGT
TCTGTGCTTTCTGTTTTTATTATTCCAAAATATTTTTTTAAAGAAGTGTTATTTTTCAACAGATTCATAAATTAGTTCCTGATGTACGGT
AAATTAAAACTCCCACTGTGTCAGTCAAACTGAGATGTGCTCATTTCATAACCACTCATTTCTAGTCTGTCAGAGCTGCACTGGTGGCTT
ATTGCTGGTTTTTAAAGGTGTTTTTAACTTACATGTAACATGTTTAGGACATGTTTTTTTTTTCTAATTTGTGTGTCTTTACAACTGATT

>98517_98517_3_VPS8-MBOAT2_VPS8_chr3_184658031_ENST00000437079_MBOAT2_chr2_9048846_ENST00000305997_length(amino acids)=1438AA_BP=1017
MLLEVNMENEPDHENVEQSLCAKTSEEELNKSFNLEASLSKFSYIDMDKELEFKNDLIDDKEFDIPQVDTPPTLESILNETDDEDESFIL
EDPTLLNIDTIDSHSYDTSSVASSDSGDRTNLKRKKKLPDSFSLHGSVMRHSLLKGISAQIVSAADKVDAGLPTAIAVSSLIAVGTSHGL
ALIFGKDQNQALRLCLGSTSVGGQYGAISALSINNDCSRLLCGFAKGQITMWDLASGKLLRSITDAHPPGTAILHIKFTDDPTLAICNDS
GGSVFELTFKRVMGVRTCESRCLFSGSKGEVCCIEPLHSKPELKDHPITQFSLLAMASLTKILVIGLKPSLKVWMTFPYGRMDPSSVPLL
AWHFVAVQNYVNPMLAFCRGDVVHFLLVKRDESGAIHVTKQKHLHLYYDLINFTWINSRTVVLLDSVEKLHVIDRQTQEELETVEISEVQ
LVYNSSHFKSLATGGNVSQALALVGEKACYQSISSYGGQIFYLGTKSVYVMMLRSWRERVDHLLKQDCLTEALALAWSFHEGKAKAVVGL
SGDASKRKAIVADRMVEILFHYADRALKKCPDQGKIQVMEQHFQDMVPVIVDYCLLLQRKDLLFSQMYDKLSENSVAKGVFLECLEPYIL
SDKLVGITPQVMKDLIVHFQDKKLMENVEALIVHMDITSLDIQQVVLMCWENRLYDAMIYVYNRGMNEFISPMEKLFRVIAPPLNAGKTL
TDEQVVMGNKLLVYISCCLAGRAYPLGDIPEDLVPLVKNQVFEFLIRLHSAEASPEEEIYPYIRTLLHFDTREFLNVLALTFEDFKNDKQ
AVEYQQRIVDILLKVMVENSDFTPSQVGCLFTFLARQLAKPDNTLFVNRTLFDQVLEFLCSPDDDSRHSERQQVLLELLQAGGIVQFEES
RLIRMAEKAEFYQICEFMYEREHQYDKIIDCYLRDPLREEEVFNYIHNILSIPGHSAEEKQSVWQKAMDHIEELVSLKPCKAAELVATHF
SGHIETVIKKLQNQVLLFKFLRSLLDPSYCFVFALGYLTVCQVTRVYIFDYGQYSADFSGPMMIITQKITSLACEIHDGMFRKDEELTSS
QRDLAVRRMPSLLEYLSYNCNFMGILAGPLCSYKDYITFIEGRSYHITQSGENGKEETQYERTEPSPNTAVVQKLLVCGLSLLFHLTICT
TLPVEYNIDEHFQATASWPTKIIYLYISLLAARPKYYFAWTLADAINNAAGFGFRGYDENGAARWDLISNLRIQQIEMSTSFKMFLDNWN
IQTALWLKRVCYERTSFSPTIQTFILSAIWHGVYPGYYLTFLTGVLMTLAARAMRNNFRHYFIEPSQLKLFYDVITWIVTQVAISYTVVP

--------------------------------------------------------------
>98517_98517_4_VPS8-MBOAT2_VPS8_chr3_184658031_ENST00000446204_MBOAT2_chr2_9048846_ENST00000305997_length(transcript)=10143nt_BP=2890nt
CACGTGGGCCGGCGGTCCACGGCCGGAATGGCAGCAAGCTCAGAGATAATCATTCAGGTCTTCGTGAGCTAAGGCCAAACAAACAAAAAA
CACTTGCTTTGATGGACTGAATACTGTTATTAGAAGTAAATATGGAAAATGAACCAGACCATGAAAATGTGGAACAGAGCCTCTGTGCCA
AGACGAGCGAAGAAGAGCTGAATAAGTCTTTCAATCTAGAAGCTTCACTTTCAAAATTCTCTTACATAGATATGGACAAGGAACTGGAGT
TCAAAAATGATCTGATTGATGACAAGGAGTTTGATATTCCTCAAGTTGATACTCCTCCAACACTGGAAAGCATACTAAATGAGACTGATG
ATGAAGATGAGTCTTTTATTCTTGAGGATCCTACATTGTTAAACATTGATACTATTGATTCTCACTCCTATGATACTTCATCTGTGGCAA
GCTCAGATAGTGGTGACAGGACCAACTTAAAAAGGAAGAAGAAATTACCTGATTCTTTTTCACTTCATGGATCAGTTATGCGCCATTCAC
TTTTGAAGGGAATTTCTGCCCAGATAGTGTCTGCAGCTGACAAAGTAGATGCTGGCTTGCCTACAGCAATTGCAGTATCCAGTCTGATAG
CAGTGGGTACATCTCATGGATTGGCTTTAATATTTGATCAGAATCAAGCTTTGCGACTCTGTCTGGGTAGCACTAGTGTTGGAGGTCAGT
ATGGCGCTATCTCTGCCCTCAGTATCAACAATGATTGCTCAAGACTTCTTTGTGGCTTTGCTAAAGGACAGATCACCATGTGGGATTTGG
CCAGTGGAAAACTTCTAAGATCAATAACAGATGCTCATCCTCCAGGAACAGCAATATTGCATATCAAGTTTACAGATGATCCAACTCTTG
CAATTTGCAACGACAGCGGAGGCTCTGTTTTTGAATTGACATTTAAGAGAGTGATGGGAGTGAGAACCTGTGAATCTAGATGTCTGTTCA
GTGGTTCCAAGGGTGAAGTCTGCTGTATTGAGCCTCTGCATTCTAAGCCTGAGTTGAAAGATCATCCCATCACACAGTTTTCATTATTGG
CCATGGCATCCTTGACAAAAATACTGGTCATTGGATTGAAACCATCCTTGAAAGTATGGATGACTTTTCCCTATGGCCGGATGGATCCTT
CCAGTGTGCCACTGCTGGCCTGGCACTTTGTAGCAGTACAAAATTACGTGAATCCCATGCTTGCCTTCTGCAGAGGAGATGTTGTTCATT
TTCTATTGGTAAAGAGAGATGAATCTGGAGCAATACATGTTACTAAGCAAAAGCATCTTCACCTATACTATGACCTCATCAACTTTACCT
GGATAAATTCACGCACAGTTGTGCTCTTAGACAGCGTAGAGAAGTTGCATGTGATTGATCGGCAAACACAAGAGGAATTGGAGACAGTGG
AGATCTCAGAAGTTCAGCTGGTCTACAATAGCAGCCATTTCAAATCACTAGCCACTGGAGGAAATGTTAGCCAGGCACTGGCTTTGGTTG
GAGAGAAGGCTTGTTATCAATCCATCAGTAGCTATGGTGGTCAGATCTTTTATTTGGGGACAAAATCTGTTTATGTGATGATGCTGAGGA
GCTGGAGAGAGAGAGTGGATCATCTCCTGAAACAAGATTGTCTTACAGAAGCGTTGGCTCTTGCGTGGTCTTTCCATGAAGGAAAAGCAA
AAGCAGTAGTGGGATTATCAGGGGATGCCAGTAAGCGAAAGGCTATTGTTGCAGACCGGATGGTAGAAATCCTATTCCATTATGCAGATC
GAGCTCTGAAAAAGTGCCCAGACCAAGGAAAAATCCAAGTGATGGAGCAGCATTTTCAGGTAGTTCTCATGTGTTGGGAAAATCGTTTAT
ATGATGCTATGATCTATGTCTACAACAGAGGCATGAATGAATTTATTAGTCCAATGGAGAAACTTTTCAGAGTCATTGCTCCTCCTCTGA
ATGCAGGAAAAACACTAACAGATGAACAAGTTGTTATGGGCAATAAGCTCCTTGTATATATTAGCTGTTGTCTAGCAGGTCGTGCCTATC
CCCTTGGTGACATCCCTGAAGATCTGGTTCCCTTGGTTAAAAACCAGGTTTTTGAATTTCTAATTCGCCTGCATTCAGCAGAGGCTTCTC
CTGAGGAAGAAATCTATCCTTACATTCGGACTTTGCTACATTTTGACACAAGAGAATTTCTAAATGTATTGGCACTGACTTTTGAAGATT
TTAAAAATGACAAGCAAGCTGTGGAATATCAACAGCGAATTGTGGATATTTTGTTGAAAGTTATGGTGGAGAATTCAGACTTTACCCCCT
CACAAGTAGGATGTCTCTTTACCTTCCTTGCTCGGCAGCTTGCAAAGCCTGACAACACCTTGTTTGTAAACAGAACACTTTTTGATCAGG
TCCTTGAATTCCTTTGTAGTCCTGACGATGACTCCCGACACTCTGAAAGACAGCAGGTCCTTTTAGAATTGCTGCAGGCTGGAGGCATAG
TTCAATTTGAAGAGAGTCGACTCATCCGGATGGCAGAAAAAGCTGAGTTCTATCAAATTTGTGAATTTATGTATGAAAGAGAACACCAAT
ATGATAAAATTATTGATTGCTACTTACGTGACCCTCTGCGAGAGGAAGAAGTCTTTAATTACATTCACAATATCTTATCCATTCCCGGAC
ACAGTGCAGAGGAGAAGCAGTCTGTATGGCAGAAAGCAATGGATCATATTGAGGAACTCGTGTCCCTGAAGCCTTGTAAAGCTGCGGAGC
TGGTTGCCACCCACTTTTCTGGACATATTGAAACGGTCATTAAAAAACTTCAGAACCAGGTTTTGCTTTTCAAATTTTTGAGGAGTCTTC
TTGACCCAAGTTACTGCTTTGTGTTTGCTCTGGGATACCTCACAGTGTGCCAAGTTACTCGAGTCTATATCTTTGACTATGGACAATATT
CTGCTGATTTTTCAGGCCCAATGATGATCATTACTCAGAAGATCACTAGTTTGGCTTGCGAAATTCATGATGGGATGTTTCGGAAGGATG
AAGAACTGACTTCCTCACAGAGGGATTTAGCTGTAAGGCGCATGCCAAGCTTACTGGAGTATTTGAGTTACAACTGTAACTTCATGGGGA
TCCTGGCAGGCCCACTTTGCTCTTACAAAGACTACATTACTTTCATTGAAGGCAGATCATACCATATCACACAATCTGGTGAAAATGGAA
AAGAAGAGACACAGTATGAAAGAACAGAGCCATCTCCAAATACTGCGGTTGTTCAGAAGCTCTTAGTTTGTGGGCTGTCCTTGTTATTTC
ACTTGACCATCTGTACAACATTACCTGTGGAGTACAACATTGATGAGCATTTTCAAGCTACAGCTTCGTGGCCAACAAAGATTATCTATC
TGTATATCTCTCTTTTGGCTGCCAGACCCAAATACTATTTTGCATGGACGCTAGCTGATGCCATTAATAATGCTGCAGGCTTTGGTTTCA
GAGGGTATGACGAAAATGGAGCAGCTCGCTGGGACTTAATTTCCAATTTGAGAATTCAACAAATAGAGATGTCAACAAGTTTCAAGATGT
TTCTTGATAATTGGAATATTCAGACAGCTCTTTGGCTCAAAAGGGTGTGTTATGAACGAACCTCCTTCAGTCCAACTATCCAGACGTTCA
TTCTCTCTGCCATTTGGCACGGGGTATACCCAGGATATTATCTAACGTTTCTAACAGGGGTGTTAATGACATTAGCAGCAAGAGCTATGA
GAAATAACTTTAGACATTATTTCATTGAACCTTCCCAACTGAAATTATTTTATGATGTTATAACATGGATAGTAACTCAAGTAGCAATAA
GTTACACAGTTGTGCCATTTGTGCTTCTTTCTATAAAACCATCACTCACGTTTTACAGCTCCTGGTATTATTGCCTGCACATTCTTGGTA
TCTTAGTATTATTGTTGTTGCCAGTGAAAAAAACTCAAAGAAGAAAGAATACACATGAAAACATTCAGCTCTCACAATCCAAAAAGTTTG
ATGAAGGAGAAAATTCTTTGGGACAGAACAGTTTTTCTACAACAAACAATGTTTGCAATCAGAATCAAGAAATAGCCTCGAGACATTCAT
CACTAAAGCAGTGATCGGGAAGGCTCTGAGGGCTGTTTTTTTTTTTTGATGTTAACAGAAACCAATCTTAGCACCTTTTCAAGGGGTTTG
AGTTTGTTGGAAAAGCAGTTAACTGGGGGGAAATGGACAGTTATAGATAAGGAATTTCCTGTACACCAGATTGGAAATGGAGTGAAACAA
GCCCTCCCATGCCATGTCTCCGTGGGCCACGCCTTATGTAAGAATATTTCCATATTTCAGTGGGCACTCCCAACCTCAGCACTTGTCCGT
AGGGTCACACGCGTGCCCTGTTGCTGAATGTATGTTGCGTATCCCAAGGCACTGAAGAGGTGGAAAAATAATCGTGTCAATCTGGATGAT
AGAGAGAAATTAACTTTTCCAAATGAATGTCTTGCCTTAAACCCTCTATTTCCTAAAATATTGTTCCTAAATGGTATTTTCAAGTGTAAT
ATTGTGAGAACGCTACTGCAGTAGTTGATGTTGTGTGCTGTAAAGGATTTTAGGAGGAATTTGAAACAGGATATTTAAGAGTGTGGATAT
TTTTAAAATGCAATAAACATCTCAGTATTTGAAGGGTTTTCTTAAAGTATGTCAAATGACTACAATCCATAGTGAAACTGTAAACAGTAA
TGGACGCCAAATTATAGGTAGCTGATTTTGCTGGAGAGTTTAATTACCTTGTGCAGTCAAAGAGCGCTTCCAGAAGGAATCTCTTAAAAC
ATAATGAGAGGTTTGGTAATGTGATATTTTAAGCTTATTCTTTTTCTTAAAAGAGAGAGGTGACGAAGGAAGGCAGGAATGAAGAAGCAC
TGCGTGGCCTCCGGTGGAATGCACGGGGCACAGCCGCGACTCTGCAGGCAGCTTCCCCCCCATGCCAGGGCTCTGCGCCGTCATGTGAGA
CTTAAAAAAAAAGTTGAATGACTTCGTGATACTTTGGACTTCTAAATTAAATTTATCAGGCATAAATTATGTAGAATTAGAGGCTTTGAA
AATAATACTGGTAGGTTGCTCAAAGGTTTTGAAAGAGAAATCGCTAGGTAGGTTACTATCTGGCTAATCCATTTCTTATCCTTGACAATT
TAATTCATATTTGGGAAACTTTTAGGGAAATGAAAAATAAAAGTCACTGAGTCTGGGTGACATTTTTTAAGAATAATATAAATTCAGTTT
CAAACTCTTCTCACATTAAAATTTTGCTGTGAACTCTTACTAAAATGAGTTTTAGGTTCTGTAAGTGGAAAAATGTGCTTTTATTTTATG
GGCCATTTTTACCACAACTAATCTTGCCTTGGATTACTAAGCATCTCCTGCGATCCCACAGAGGACTGTGGTGGCCACAGGAGCTGAAAG
CAGAAGAGTGGGATTTGATGCCAGGCAGTGGAGTGGCCTCAGCCCCAGATTGTACCTCCTGCCCTGTAGGAGGGGAGGGGGCAAAGCCTT
CTGACTTCACCTTTGTTTGACCTATGTATGGAACTTACTTTTACTTTTTGCCTTAAATTTTTAATGAAATGCAAATTTTCTGTGATGGGG
TTCTCTCTCTCTTTTTTTCGGGGGGTGGAGTCACTAATAAATTTGCAAATGAAGTTAAAGACAAGGCAACCATCTGGCTTATGCTATATA
ATACTTCATTTAAAGAAGAAAGGAAAAGCAAATGCACTTGCAGCTTTTGAGGTCTCAGCAAAAATGGGCATGTGTCTTTTTTGAAGTTTA
GAAATATCCTAATCTATTTTTATTTATCTAAAAGTAAGTGTTTTCCGGCTGATAAGGCTAACCCTACCCAGGAAAGGATTGATAACTAAA
TAAATTTCCTCTGTTTTCCCATGCATTGAAATTATGTTGGCTGAGCATGGTGGCTCACACCTGTAATCCTAGCACTTTGGGAGGCCGAGG
TGGGCGGATCACTTGAGGTCAGGAGTTGGAGACCAGCCTGGCCAACGTGGTGAATCCCCGTCTCTACTGAAAACACAAAAATTAGACGGG
CATGGTGGCGCACACCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATTGCTTGAACCTGGGAGGTGGAGGTTGCAGTGAGCTA
AAATTGTGCCACTGCACTCCAGCCTGGGTGACAGAGGAAGACTCCGTCTCACAAAAAAAAAAAAAGAAAAAAGAAATTATGCCAGCTGTT
TAATGTGAGAGAATAGAAAGAATGTTCATGGAATGTACCTGCCCTGTAAAATGTTTGATCATTTTCATTAATGTTGCAGAGAATCCGACT
GCTATTAAGAGAAAGTGAACAAATTAAGAATTTAAAAGACAGGTTCAGGCATGTCATAAGTGAAAACAAGAAGGCTTAATACAAACTTGT
TGGGTTTTGTTCGTGTGTGTGTGTGTGTGTGTGTGTGTGTTTTTTTTTGGTTCAGCCTATCTAGCCACCTACAAATAATCACATTTCTGT
TACCTGAATTTATTTCTCAGCCTGTAAACCTTAGTCACTGTTACCTGTTTCTTGCTCAGTGAATATGATCTTGGCACTGTCATCTAGAAA
GCAAGATATTTGATTGGTTTTCTGGTTCCTTCGAAGATAATAATTCCATATCCAGTTTGACTGATTTTCATACCCCTGAATCAACTAGTT
ATTTTCATGAAATGGTTTTTGGATATCTCTCCTCTAGTTTGGAGAAGTAATAATCACAAAGATTAATATTTTGCTTCTAGTACTTACAGT
AGAAGAATTTTAAACTGGTACGTCTACTCCTGTTAAATAGAAAGGGGATTCGTTGTATTATGTGCTTGCTTTTTTTTAATCAATAGAATA
AGATTCAATGCATATTTATGTTTTATATTTTCCACTATTCAGGTATCATGAAATCACTCTAGAGATGATCAATCAACATCATATTTATAC
TTTTGGTTAATTATATACTACTCAGGGAAAAAATGAACAAAAATAACTACTCATCCTTCAATTTCATTTTCTTGAAACAGTAAGAGTATA
ATTTGGTATGCCTCAGCTGTCACCATTTTATAAGTGGCTCATTCTGTTCTTAAAGTAAGTATTTTTATTGGAACTCAGGGTAATTGGGGG
AATTTATTTAGCTTCTAAAATATCCGGCAGGATAGAGAAGATTTATTTGGCTTCAAAAATGTCTGGTGACCACTTCTCTTATTAGCCACT
ACTGCCCATTTGCTTCAAAAATATATTTATTGGTCTCCACCATGTGTGACACACACAGGATTTCCAAACATACCACTTTTGAGAAAAATG
TGCAGTAAAAAGGAGGTTTCTAGAAAGTGACAGTAACTCACATTTAAGCACTAGCTGACCTAGGAGGAGACCTGGATCTTCATTCTGGTT
CTGCCTTTCATGAGACTTAAGACTTGGAGGAGCCACCTGTCCTGTAGACCCCAAGTTCCTCAGCCATAAGCAAACGGGTTAATCCTAAGA
GTTCAGGACCAGTTGGGTGTCGTGAACGGAGCCATTAGCAAGGTCTGTAGGATTCAAGGACTTGGGCACATTCACAGTCCACACTATTGT
CATGGTCATTGACTTACTACTTGAGCTCAAAGCCCTGACATTTCAAAAGGTTGTCATGATAACAGTGAAACCTCTGAATCCCTTAAATCA
GAAGGCATGGCAACATACTTTTTCTACTGGCAATAGCTCTTACAATGAGTGTTTCATAATGAAATAGTCTCTGCTGAAGAAAACATGTTT
TCCTTTTGCTCTCTCTGCTTTGTTGGTTTCTGTGCTGTGTGGAATTGGAGAAGATATATGCTCTGAAATATTTTATACAGATTACTGACT
ACTGGACAGGGTTTACCACTATATAACATCTCAAAGTTATTCAAGGATATTTAAAGCATATTTAGTTTAGTTACACCTTATTTTAAACCG
CAGAAAACAATAGCTTTAAAATTTTTGCCATTAAAATAATTATAAATTTATACTTTTACTCAAGGACTAGATCACAGTTTTAGGACAAAA
ATCTCTCCTATTTAAAGTTCATACCTTGTAAGTATTTAGTTTGTATATTCATGAACAAATCTGGACATTTATACTTTTTTTGTTTCCTTA
TCAACTGTTCACAATTATTAGTTAATTGGTCTTAACAGTTCTACATTATAATTGAAAGAAAAATTACTTGAGAAAATAATTGTTTCAGAA
TAGTGCCTACTATATCTGTGTCAGCTAAAAATTTGTCCAGAGTTTTAGATATAAGCTAGTATTTTGTGGAGTTTTATCCAGGCGTTAATA
GTTCTTCCTGGCTGAAATTTAATATAGGTGCAGAATCCTAAATAACACTGTGAGATGTAATCTTAACTGCCCTCAATACCTTATAAAACT
GCTGCATTTAACCCAGTGTGCATTTAATGAGTGGCTGGTCGTTGATACACTCATCTTAGATGCTGAAATTTCTGTTTTCTCCAGCCCTTG
TAAAAGTGGGTTTCTTGATGAACGCGTGCTCCCAATGCTGAAGCAAAAGATTTGCATTTAAGGAGAGAAATACACCCTGAAATTTGAGTT
TGAAAGATTAGAACATAGAGGGTCTCTACAGTGTTTTTCTGCAACACCAAGTAGTCAAATCTATTTATAGAAACTCTGATTACAACAGAA
ATTTTAAAATGAAATTTTCCACATCGGTATTTTGTAGGAAAGCTCTTATAATCAATGCTTAAGCTGCTTTTTGAGGCTTTTCTTGTACAG
AGGTTGCAGCCAATTACATTTTAATTGGTAGGCTGCTGAATAATGTTTTTGTATGTTTTAAAATAATATTTATTTTAATAGGTTTTTTAA
CATTATGCAAATCCCAATAAAGAACTGACACGTTCCATAGGCCATTGACTGGGAAATTTTGTGAAACACAGCCTAAATACACAGTTTTTA
CACCAACTAATTTGTCTTGCCTTTAAAACTGATTATAACTCTTCTTTAAGTACAACTTTTATAAAGAAAAAATACAACACTAAGACTGTA
TGTTCTGTAAATTATAGTGTGATGACCCATGCAGAACCGCTGTCTGAAGCTTACTCAGCGATTCATAGCCATCTCCAGCCATGTTTTATC
AAATCACACACTAAAAATAAATGGAAATGCTACAGTGAAAAACCAAAAGTTACAGAGCAACATAAGTAAAATGACTAGGCAGTTTCTTAG
TAACATGTTTGAAATGGGAAAGGTGACTGACTGCCTTTCACCAGAGTCTTAGCTGTTTCACGTTCACTATTTTAGGTTAATTTTCTTGGG
AAATCAATTTGAATATTCCCCCCTGTCCTTTTGCATTAAAGGACGAAAATATATGTTGAGAGTTTGACAGACTTTTTAAATATGCCTCTT
TCCCAATTTTATGTATTTTTGGTTCTGCGCACACAGATTTATCAATGAAGTACATTTGCCTCTGGCTTTATCACAAGGAAAAAGGAATCA
AACATTGAACACAAATGTGTTCCAAACCAGTCTTGTCCATCTTGTCACTTTTATGTGACTGCTCCTCTGAACCAGAAGGGGCACGATAGA
AGGCCATAGGAATGAAAGTAAATCATTCAGGTGAAGTGAGAAATTCTTCCATATACAGAGTGAAAATGTGTGATTTCATTCCTGCCTTCC
TTTAAACGTTGTCTTGATCTCTGCCTAGTAGTAGTTGAGCCCTCAGTCGCCCAAACATGAGGAGAGACCCAACTCCAGCAGCCAGAATTT
AGTATTTACATTTGCCTTCCCAAGTTGAGAATAGAATGTGGTGTTCTGTGCTTTCTGTTTTTATTATTCCAAAATATTTTTTTAAAGAAG
TGTTATTTTTCAACAGATTCATAAATTAGTTCCTGATGTACGGTAAATTAAAACTCCCACTGTGTCAGTCAAACTGAGATGTGCTCATTT
CATAACCACTCATTTCTAGTCTGTCAGAGCTGCACTGGTGGCTTATTGCTGGTTTTTAAAGGTGTTTTTAACTTACATGTAACATGTTTA

>98517_98517_4_VPS8-MBOAT2_VPS8_chr3_184658031_ENST00000446204_MBOAT2_chr2_9048846_ENST00000305997_length(amino acids)=1346AA_BP=925
MLLEVNMENEPDHENVEQSLCAKTSEEELNKSFNLEASLSKFSYIDMDKELEFKNDLIDDKEFDIPQVDTPPTLESILNETDDEDESFIL
EDPTLLNIDTIDSHSYDTSSVASSDSGDRTNLKRKKKLPDSFSLHGSVMRHSLLKGISAQIVSAADKVDAGLPTAIAVSSLIAVGTSHGL
ALIFDQNQALRLCLGSTSVGGQYGAISALSINNDCSRLLCGFAKGQITMWDLASGKLLRSITDAHPPGTAILHIKFTDDPTLAICNDSGG
SVFELTFKRVMGVRTCESRCLFSGSKGEVCCIEPLHSKPELKDHPITQFSLLAMASLTKILVIGLKPSLKVWMTFPYGRMDPSSVPLLAW
HFVAVQNYVNPMLAFCRGDVVHFLLVKRDESGAIHVTKQKHLHLYYDLINFTWINSRTVVLLDSVEKLHVIDRQTQEELETVEISEVQLV
YNSSHFKSLATGGNVSQALALVGEKACYQSISSYGGQIFYLGTKSVYVMMLRSWRERVDHLLKQDCLTEALALAWSFHEGKAKAVVGLSG
DASKRKAIVADRMVEILFHYADRALKKCPDQGKIQVMEQHFQVVLMCWENRLYDAMIYVYNRGMNEFISPMEKLFRVIAPPLNAGKTLTD
EQVVMGNKLLVYISCCLAGRAYPLGDIPEDLVPLVKNQVFEFLIRLHSAEASPEEEIYPYIRTLLHFDTREFLNVLALTFEDFKNDKQAV
EYQQRIVDILLKVMVENSDFTPSQVGCLFTFLARQLAKPDNTLFVNRTLFDQVLEFLCSPDDDSRHSERQQVLLELLQAGGIVQFEESRL
IRMAEKAEFYQICEFMYEREHQYDKIIDCYLRDPLREEEVFNYIHNILSIPGHSAEEKQSVWQKAMDHIEELVSLKPCKAAELVATHFSG
HIETVIKKLQNQVLLFKFLRSLLDPSYCFVFALGYLTVCQVTRVYIFDYGQYSADFSGPMMIITQKITSLACEIHDGMFRKDEELTSSQR
DLAVRRMPSLLEYLSYNCNFMGILAGPLCSYKDYITFIEGRSYHITQSGENGKEETQYERTEPSPNTAVVQKLLVCGLSLLFHLTICTTL
PVEYNIDEHFQATASWPTKIIYLYISLLAARPKYYFAWTLADAINNAAGFGFRGYDENGAARWDLISNLRIQQIEMSTSFKMFLDNWNIQ
TALWLKRVCYERTSFSPTIQTFILSAIWHGVYPGYYLTFLTGVLMTLAARAMRNNFRHYFIEPSQLKLFYDVITWIVTQVAISYTVVPFV

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Fusion Gene PPI Analysis for VPS8-MBOAT2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for VPS8-MBOAT2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for VPS8-MBOAT2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource