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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:VTI1A-GLUD1 (FusionGDB2 ID:98588)

Fusion Gene Summary for VTI1A-GLUD1

check button Fusion gene summary
Fusion gene informationFusion gene name: VTI1A-GLUD1
Fusion gene ID: 98588
HgeneTgene
Gene symbol

VTI1A

GLUD1

Gene ID

143187

2746

Gene namevesicle transport through interaction with t-SNAREs 1Aglutamate dehydrogenase 1
SynonymsMMDS3|MVti1|VTI1RP2|Vti1-rp2GDH|GDH1|GLUD
Cytomap

10q25.2

10q23.2

Type of geneprotein-codingprotein-coding
Descriptionvesicle transport through interaction with t-SNAREs homolog 1ASNARE Vti1a-beta proteinvesicle transport v-SNARE protein Vti1-like 2glutamate dehydrogenase 1, mitochondrialepididymis secretory sperm binding proteinepididymis tissue sperm binding protein Li 18mPglutamate dehydrogenase (NAD(P)+)
Modification date2020031320200329
UniProtAcc.

P00367

Ensembl transtripts involved in fusion geneENST00000393077, ENST00000432306, 
ENST00000483122, 		ENST00000465164, 
ENST00000277865, ENST00000537649, 
ENST00000544149, 
Fusion gene scores* DoF score15 X 12 X 12=216010 X 7 X 8=560
# samples 2411
** MAII scorelog2(24/2160*10)=-3.16992500144231
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(11/560*10)=-2.34792330342031
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: VTI1A [Title/Abstract] AND GLUD1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointVTI1A(114298089)-GLUD1(88827914), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneVTI1A

GO:0042147

retrograde transport, endosome to Golgi

15215310|18195106

TgeneGLUD1

GO:0006537

glutamate biosynthetic process

11032875

TgeneGLUD1

GO:0006538

glutamate catabolic process

6121377|11032875


check buttonFusion gene breakpoints across VTI1A (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across GLUD1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-09-2051VTI1Achr10

114298089

+GLUD1chr10

88827914

-


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Fusion Gene ORF analysis for VTI1A-GLUD1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000393077ENST00000465164VTI1Achr10

114298089

+GLUD1chr10

88827914

-
5CDS-intronENST00000432306ENST00000465164VTI1Achr10

114298089

+GLUD1chr10

88827914

-
In-frameENST00000393077ENST00000277865VTI1Achr10

114298089

+GLUD1chr10

88827914

-
In-frameENST00000393077ENST00000537649VTI1Achr10

114298089

+GLUD1chr10

88827914

-
In-frameENST00000393077ENST00000544149VTI1Achr10

114298089

+GLUD1chr10

88827914

-
In-frameENST00000432306ENST00000277865VTI1Achr10

114298089

+GLUD1chr10

88827914

-
In-frameENST00000432306ENST00000537649VTI1Achr10

114298089

+GLUD1chr10

88827914

-
In-frameENST00000432306ENST00000544149VTI1Achr10

114298089

+GLUD1chr10

88827914

-
intron-3CDSENST00000483122ENST00000277865VTI1Achr10

114298089

+GLUD1chr10

88827914

-
intron-3CDSENST00000483122ENST00000537649VTI1Achr10

114298089

+GLUD1chr10

88827914

-
intron-3CDSENST00000483122ENST00000544149VTI1Achr10

114298089

+GLUD1chr10

88827914

-
intron-intronENST00000483122ENST00000465164VTI1Achr10

114298089

+GLUD1chr10

88827914

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000432306VTI1Achr10114298089+ENST00000277865GLUD1chr1088827914-2839543861573495
ENST00000432306VTI1Achr10114298089+ENST00000537649GLUD1chr1088827914-2835543861573495
ENST00000432306VTI1Achr10114298089+ENST00000544149GLUD1chr1088827914-1724543861573495
ENST00000393077VTI1Achr10114298089+ENST00000277865GLUD1chr1088827914-2839543861573495
ENST00000393077VTI1Achr10114298089+ENST00000537649GLUD1chr1088827914-2835543861573495
ENST00000393077VTI1Achr10114298089+ENST00000544149GLUD1chr1088827914-1724543861573495

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000432306ENST00000277865VTI1Achr10114298089+GLUD1chr1088827914-0.0004186730.9995813
ENST00000432306ENST00000537649VTI1Achr10114298089+GLUD1chr1088827914-0.0004177670.99958223
ENST00000432306ENST00000544149VTI1Achr10114298089+GLUD1chr1088827914-0.000778060.9992219
ENST00000393077ENST00000277865VTI1Achr10114298089+GLUD1chr1088827914-0.0004186730.9995813
ENST00000393077ENST00000537649VTI1Achr10114298089+GLUD1chr1088827914-0.0004177670.99958223
ENST00000393077ENST00000544149VTI1Achr10114298089+GLUD1chr1088827914-0.000778060.9992219

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Fusion Genomic Features for VTI1A-GLUD1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for VTI1A-GLUD1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr10:114298089/chr10:88827914)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.GLUD1

P00367

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Mitochondrial glutamate dehydrogenase that catalyzes the conversion of L-glutamate into alpha-ketoglutarate. Plays a key role in glutamine anaplerosis by producing alpha-ketoglutarate, an important intermediate in the tricarboxylic acid cycle (PubMed:11032875, PubMed:16959573, PubMed:11254391, PubMed:16023112). Plays a role in insulin homeostasis (PubMed:9571255, PubMed:11297618). May be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate (By similarity). {ECO:0000250|UniProtKB:P10860, ECO:0000269|PubMed:11032875, ECO:0000269|PubMed:11254391, ECO:0000269|PubMed:11297618, ECO:0000269|PubMed:16023112, ECO:0000269|PubMed:16959573, ECO:0000269|PubMed:9571255}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneVTI1Achr10:114298089chr10:88827914ENST00000393077+5831_92142218.0Coiled coilOntology_term=ECO:0000255
HgeneVTI1Achr10:114298089chr10:88827914ENST00000432306+5831_92142204.0Coiled coilOntology_term=ECO:0000255

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneVTI1Achr10:114298089chr10:88827914ENST00000393077+58112_178142218.0Coiled coilOntology_term=ECO:0000255
HgeneVTI1Achr10:114298089chr10:88827914ENST00000432306+58112_178142204.0Coiled coilOntology_term=ECO:0000255
HgeneVTI1Achr10:114298089chr10:88827914ENST00000393077+581_192142218.0Topological domainCytoplasmic
HgeneVTI1Achr10:114298089chr10:88827914ENST00000393077+58214_217142218.0Topological domainExtracellular
HgeneVTI1Achr10:114298089chr10:88827914ENST00000432306+581_192142204.0Topological domainCytoplasmic
HgeneVTI1Achr10:114298089chr10:88827914ENST00000432306+58214_217142204.0Topological domainExtracellular
HgeneVTI1Achr10:114298089chr10:88827914ENST00000393077+58193_213142218.0TransmembraneHelical
HgeneVTI1Achr10:114298089chr10:88827914ENST00000432306+58193_213142204.0TransmembraneHelical
TgeneGLUD1chr10:114298089chr10:88827914ENST00000277865313141_143215559.0Nucleotide bindingNAD


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Fusion Gene Sequence for VTI1A-GLUD1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>98588_98588_1_VTI1A-GLUD1_VTI1A_chr10_114298089_ENST00000393077_GLUD1_chr10_88827914_ENST00000277865_length(transcript)=2839nt_BP=543nt
CCGTTCTGCTCTCGGGGGCACCTTCCGGGGTTCCTAAGCCGCGGGGCCCCTCGCTGCCCCTCGAGGCCCTTTCCCTGACCTAGGCTTTGG
CCTGGGCTACTCGTTCCGGAGCCGCCATGTCGTCCGACTTCGAAGGTTACGAGCAGGACTTCGCGGTGCTCACTGCAGAGATCACCAGCA
AGATTGCGAGGGTCCCACGACTCCCGCCTGATGAAAAGAAACAGATGGTTGCAAATGTGGAGAAACAGCTTGAAGAAGCGAAAGAACTGC
TTGAACAGATGGATTTGGAAGTCCGAGAGATACCACCCCAAAGTCGAGGGATGTACAGCAACAGAATGAGAAGCTACAAACAAGAAATGG
GAAAACTCGAAACAGATTTTAAAAGGTCACGGATCGCCTACAGTGACGAAGTACGGAATGAGCTCCTGGGGGATGATGGGAATTCCTCAG
AGAACCAGAGGGCACATCTGCTCGATAACACAGAGAGGCTGGAAAGGTCATCTCGGAGACTAGAGGCTGGATACCAAATAGCAGTGGAAA
CCGGTCCTGGCATTGATGTGCCTGCTCCAGACATGAGCACAGGTGAGCGGGAGATGTCCTGGATCGCTGATACCTATGCCAGCACCATAG
GGCACTATGATATTAATGCACACGCCTGTGTTACTGGTAAACCCATCAGCCAAGGGGGAATCCATGGACGCATCTCTGCTACTGGCCGTG
GTGTCTTCCATGGGATTGAAAATTTCATCAATGAAGCTTCTTACATGAGCATTTTAGGAATGACACCAGGGTTTGGAGATAAAACATTTG
TTGTTCAGGGATTTGGTAATGTGGGCCTACACTCTATGAGATATTTACATCGTTTTGGTGCTAAATGTATTGCTGTTGGTGAGTCTGATG
GGAGTATATGGAATCCAGATGGTATTGACCCAAAGGAACTGGAAGACTTCAAATTGCAACATGGGTCCATTCTGGGCTTCCCCAAGGCAA
AGCCCTATGAAGGAAGCATCTTGGAGGCCGACTGTGACATACTGATCCCAGCTGCCAGTGAGAAGCAGTTGACCAAATCCAACGCACCCA
GAGTCAAAGCCAAGATCATTGCTGAAGGTGCCAATGGGCCAACAACTCCAGAAGCTGACAAGATCTTCCTGGAGAGAAACATTATGGTTA
TTCCAGATCTCTACTTGAATGCTGGAGGAGTGACAGTATCTTACTTTGAGTGGCTGAAGAATCTAAATCATGTCAGCTATGGCCGTTTGA
CCTTCAAATATGAAAGGGATTCTAACTACCACTTGCTCATGTCTGTTCAAGAGAGTTTAGAAAGAAAATTTGGAAAGCATGGTGGAACTA
TTCCCATTGTACCCACGGCAGAGTTCCAAGACAGGATATCGGGTGCATCTGAGAAAGACATCGTGCACTCTGGCTTGGCATACACAATGG
AGCGTTCTGCCAGGCAAATTATGCGCACAGCCATGAAGTATAACCTGGGATTGGACCTGAGAACAGCTGCCTATGTTAATGCCATTGAGA
AAGTCTTCAAAGTGTACAATGAAGCTGGTGTGACCTTCACATAGATGGATCATGGCTGACTTCCTCACTATCCTCTTCACATGTAACTTC
TGCAGACCTATCACAAGTTTACATGTAACCACAGAAATCCCTTTCTCTCCTGACTCATTAATAATGGATACCATTCTCAACAAGTCAATC
CAAGTCAGCCCGTTAAGGAGAAAGAAATTAAGGTTAGCGGATCATGTACAAGCTGAGTGTGAAAGTAGAAATCACCTACACCAGAGAGCC
ATTTTGGTATTTTGCCTTTAAATAAAAAGCCTCCTTTATCTGGCTGTGCAGCCTTGCTCTGTGGCTTTTCCCAACACAATCAGTGCTAGT
GCTGGGGAGGAACAGTCAAGAGCAGTCAGTTGCTTGCTTATTTTTTCTGGATGAGTCTGGGACACACTGTAACTTTAACACATTTAAGAA
GTAGGTGTGTGGCCTTTTCAGAAGGTGGCATGGTCCTCAAGTGAGTTCTTAGTATTTTATATCAGCAAAATAATTCAATTTTGCAGGTTG
CAAACAAATATAAAACCTGTTTCTGTTTATGAATATTATTCTTTTAGAATAGAATAAGTACATGCTGCTGTAATAAAATTGCCTTTAATC
ACTTAACAAGCCTAACCTTGACTCAAACAGTGAATGCCTATAGAAATAATAAATGAAAAAAACTAGTATTTTTATATCATAAAACAATGT
CATTTATAGCTTATCATTCATGTATTGTCCAGCAGACATTAAAAGCCCTGTGGATAATTAAGTTATCTTCATACCTGCAAAATGGTGGAG
GCTATTTTCATTAAAACTGTCAGAATTTGCTTACTATAATTATGATACAGTCCAAAGAATGCAGTCACTTTTTATCATGTTAACTAATTG
TTCTCTTTTGAAGATCTATGGTTGACTAATTAAACAATAATTCAAGTAGAGTGTCCCAGAAAAAAACCACTTGGGCTCCCTGTTTGGAGT
CTGGCTGGCTCTGAGCATTGCCAATGGCCCCTACTCACCTGACTTTGTATCCTCTCCTTTTAGAGGCTTTGCATTCTGCACCCAGCTTCA
CTAACAGTGGGCTGAAAACATCCTTGGGTTGAGTGTTTCATTTGGGAGTTATTTGGCCAGGGCCTTTTGAACAGTAGTGTCCCCATGAAG
TGCTAGATAATATATGTGTAAGAGTCAGCTTTTTTTTTTTTTTTAACTCTAACACCCTTCAGAAATTTCTAACTACTTTGTAACTGCATG

>98588_98588_1_VTI1A-GLUD1_VTI1A_chr10_114298089_ENST00000393077_GLUD1_chr10_88827914_ENST00000277865_length(amino acids)=495AA_BP=152
MAWATRSGAAMSSDFEGYEQDFAVLTAEITSKIARVPRLPPDEKKQMVANVEKQLEEAKELLEQMDLEVREIPPQSRGMYSNRMRSYKQE
MGKLETDFKRSRIAYSDEVRNELLGDDGNSSENQRAHLLDNTERLERSSRRLEAGYQIAVETGPGIDVPAPDMSTGEREMSWIADTYAST
IGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGES
DGSIWNPDGIDPKELEDFKLQHGSILGFPKAKPYEGSILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLERNIM
VIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMSVQESLERKFGKHGGTIPIVPTAEFQDRISGASEKDIVHSGLAYT

--------------------------------------------------------------
>98588_98588_2_VTI1A-GLUD1_VTI1A_chr10_114298089_ENST00000393077_GLUD1_chr10_88827914_ENST00000537649_length(transcript)=2835nt_BP=543nt
CCGTTCTGCTCTCGGGGGCACCTTCCGGGGTTCCTAAGCCGCGGGGCCCCTCGCTGCCCCTCGAGGCCCTTTCCCTGACCTAGGCTTTGG
CCTGGGCTACTCGTTCCGGAGCCGCCATGTCGTCCGACTTCGAAGGTTACGAGCAGGACTTCGCGGTGCTCACTGCAGAGATCACCAGCA
AGATTGCGAGGGTCCCACGACTCCCGCCTGATGAAAAGAAACAGATGGTTGCAAATGTGGAGAAACAGCTTGAAGAAGCGAAAGAACTGC
TTGAACAGATGGATTTGGAAGTCCGAGAGATACCACCCCAAAGTCGAGGGATGTACAGCAACAGAATGAGAAGCTACAAACAAGAAATGG
GAAAACTCGAAACAGATTTTAAAAGGTCACGGATCGCCTACAGTGACGAAGTACGGAATGAGCTCCTGGGGGATGATGGGAATTCCTCAG
AGAACCAGAGGGCACATCTGCTCGATAACACAGAGAGGCTGGAAAGGTCATCTCGGAGACTAGAGGCTGGATACCAAATAGCAGTGGAAA
CCGGTCCTGGCATTGATGTGCCTGCTCCAGACATGAGCACAGGTGAGCGGGAGATGTCCTGGATCGCTGATACCTATGCCAGCACCATAG
GGCACTATGATATTAATGCACACGCCTGTGTTACTGGTAAACCCATCAGCCAAGGGGGAATCCATGGACGCATCTCTGCTACTGGCCGTG
GTGTCTTCCATGGGATTGAAAATTTCATCAATGAAGCTTCTTACATGAGCATTTTAGGAATGACACCAGGGTTTGGAGATAAAACATTTG
TTGTTCAGGGATTTGGTAATGTGGGCCTACACTCTATGAGATATTTACATCGTTTTGGTGCTAAATGTATTGCTGTTGGTGAGTCTGATG
GGAGTATATGGAATCCAGATGGTATTGACCCAAAGGAACTGGAAGACTTCAAATTGCAACATGGGTCCATTCTGGGCTTCCCCAAGGCAA
AGCCCTATGAAGGAAGCATCTTGGAGGCCGACTGTGACATACTGATCCCAGCTGCCAGTGAGAAGCAGTTGACCAAATCCAACGCACCCA
GAGTCAAAGCCAAGATCATTGCTGAAGGTGCCAATGGGCCAACAACTCCAGAAGCTGACAAGATCTTCCTGGAGAGAAACATTATGGTTA
TTCCAGATCTCTACTTGAATGCTGGAGGAGTGACAGTATCTTACTTTGAGTGGCTGAAGAATCTAAATCATGTCAGCTATGGCCGTTTGA
CCTTCAAATATGAAAGGGATTCTAACTACCACTTGCTCATGTCTGTTCAAGAGAGTTTAGAAAGAAAATTTGGAAAGCATGGTGGAACTA
TTCCCATTGTACCCACGGCAGAGTTCCAAGACAGGATATCGGGTGCATCTGAGAAAGACATCGTGCACTCTGGCTTGGCATACACAATGG
AGCGTTCTGCCAGGCAAATTATGCGCACAGCCATGAAGTATAACCTGGGATTGGACCTGAGAACAGCTGCCTATGTTAATGCCATTGAGA
AAGTCTTCAAAGTGTACAATGAAGCTGGTGTGACCTTCACATAGATGGATCATGGCTGACTTCCTCACTATCCTCTTCACATGTAACTTC
TGCAGACCTATCACAAGTTTACATGTAACCACAGAAATCCCTTTCTCTCCTGACTCATTAATAATGGATACCATTCTCAACAAGTCAATC
CAAGTCAGCCCGTTAAGGAGAAAGAAATTAAGGTTAGCGGATCATGTACAAGCTGAGTGTGAAAGTAGAAATCACCTACACCAGAGAGCC
ATTTTGGTATTTTGCCTTTAAATAAAAAGCCTCCTTTATCTGGCTGTGCAGCCTTGCTCTGTGGCTTTTCCCAACACAATCAGTGCTAGT
GCTGGGGAGGAACAGTCAAGAGCAGTCAGTTGCTTGCTTATTTTTTCTGGATGAGTCTGGGACACACTGTAACTTTAACACATTTAAGAA
GTAGGTGTGTGGCCTTTTCAGAAGGTGGCATGGTCCTCAAGTGAGTTCTTAGTATTTTATATCAGCAAAATAATTCAATTTTGCAGGTTG
CAAACAAATATAAAACCTGTTTCTGTTTATGAATATTATTCTTTTAGAATAGAATAAGTACATGCTGCTGTAATAAAATTGCCTTTAATC
ACTTAACAAGCCTAACCTTGACTCAAACAGTGAATGCCTATAGAAATAATAAATGAAAAAAACTAGTATTTTTATATCATAAAACAATGT
CATTTATAGCTTATCATTCATGTATTGTCCAGCAGACATTAAAAGCCCTGTGGATAATTAAGTTATCTTCATACCTGCAAAATGGTGGAG
GCTATTTTCATTAAAACTGTCAGAATTTGCTTACTATAATTATGATACAGTCCAAAGAATGCAGTCACTTTTTATCATGTTAACTAATTG
TTCTCTTTTGAAGATCTATGGTTGACTAATTAAACAATAATTCAAGTAGAGTGTCCCAGAAAAAAACCACTTGGGCTCCCTGTTTGGAGT
CTGGCTGGCTCTGAGCATTGCCAATGGCCCCTACTCACCTGACTTTGTATCCTCTCCTTTTAGAGGCTTTGCATTCTGCACCCAGCTTCA
CTAACAGTGGGCTGAAAACATCCTTGGGTTGAGTGTTTCATTTGGGAGTTATTTGGCCAGGGCCTTTTGAACAGTAGTGTCCCCATGAAG
TGCTAGATAATATATGTGTAAGAGTCAGCTTTTTTTTTTTTTTTAACTCTAACACCCTTCAGAAATTTCTAACTACTTTGTAACTGCATG

>98588_98588_2_VTI1A-GLUD1_VTI1A_chr10_114298089_ENST00000393077_GLUD1_chr10_88827914_ENST00000537649_length(amino acids)=495AA_BP=152
MAWATRSGAAMSSDFEGYEQDFAVLTAEITSKIARVPRLPPDEKKQMVANVEKQLEEAKELLEQMDLEVREIPPQSRGMYSNRMRSYKQE
MGKLETDFKRSRIAYSDEVRNELLGDDGNSSENQRAHLLDNTERLERSSRRLEAGYQIAVETGPGIDVPAPDMSTGEREMSWIADTYAST
IGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGES
DGSIWNPDGIDPKELEDFKLQHGSILGFPKAKPYEGSILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLERNIM
VIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMSVQESLERKFGKHGGTIPIVPTAEFQDRISGASEKDIVHSGLAYT

--------------------------------------------------------------
>98588_98588_3_VTI1A-GLUD1_VTI1A_chr10_114298089_ENST00000393077_GLUD1_chr10_88827914_ENST00000544149_length(transcript)=1724nt_BP=543nt
CCGTTCTGCTCTCGGGGGCACCTTCCGGGGTTCCTAAGCCGCGGGGCCCCTCGCTGCCCCTCGAGGCCCTTTCCCTGACCTAGGCTTTGG
CCTGGGCTACTCGTTCCGGAGCCGCCATGTCGTCCGACTTCGAAGGTTACGAGCAGGACTTCGCGGTGCTCACTGCAGAGATCACCAGCA
AGATTGCGAGGGTCCCACGACTCCCGCCTGATGAAAAGAAACAGATGGTTGCAAATGTGGAGAAACAGCTTGAAGAAGCGAAAGAACTGC
TTGAACAGATGGATTTGGAAGTCCGAGAGATACCACCCCAAAGTCGAGGGATGTACAGCAACAGAATGAGAAGCTACAAACAAGAAATGG
GAAAACTCGAAACAGATTTTAAAAGGTCACGGATCGCCTACAGTGACGAAGTACGGAATGAGCTCCTGGGGGATGATGGGAATTCCTCAG
AGAACCAGAGGGCACATCTGCTCGATAACACAGAGAGGCTGGAAAGGTCATCTCGGAGACTAGAGGCTGGATACCAAATAGCAGTGGAAA
CCGGTCCTGGCATTGATGTGCCTGCTCCAGACATGAGCACAGGTGAGCGGGAGATGTCCTGGATCGCTGATACCTATGCCAGCACCATAG
GGCACTATGATATTAATGCACACGCCTGTGTTACTGGTAAACCCATCAGCCAAGGGGGAATCCATGGACGCATCTCTGCTACTGGCCGTG
GTGTCTTCCATGGGATTGAAAATTTCATCAATGAAGCTTCTTACATGAGCATTTTAGGAATGACACCAGGGTTTGGAGATAAAACATTTG
TTGTTCAGGGATTTGGTAATGTGGGCCTACACTCTATGAGATATTTACATCGTTTTGGTGCTAAATGTATTGCTGTTGGTGAGTCTGATG
GGAGTATATGGAATCCAGATGGTATTGACCCAAAGGAACTGGAAGACTTCAAATTGCAACATGGGTCCATTCTGGGCTTCCCCAAGGCAA
AGCCCTATGAAGGAAGCATCTTGGAGGCCGACTGTGACATACTGATCCCAGCTGCCAGTGAGAAGCAGTTGACCAAATCCAACGCACCCA
GAGTCAAAGCCAAGATCATTGCTGAAGGTGCCAATGGGCCAACAACTCCAGAAGCTGACAAGATCTTCCTGGAGAGAAACATTATGGTTA
TTCCAGATCTCTACTTGAATGCTGGAGGAGTGACAGTATCTTACTTTGAGTGGCTGAAGAATCTAAATCATGTCAGCTATGGCCGTTTGA
CCTTCAAATATGAAAGGGATTCTAACTACCACTTGCTCATGTCTGTTCAAGAGAGTTTAGAAAGAAAATTTGGAAAGCATGGTGGAACTA
TTCCCATTGTACCCACGGCAGAGTTCCAAGACAGGATATCGGGTGCATCTGAGAAAGACATCGTGCACTCTGGCTTGGCATACACAATGG
AGCGTTCTGCCAGGCAAATTATGCGCACAGCCATGAAGTATAACCTGGGATTGGACCTGAGAACAGCTGCCTATGTTAATGCCATTGAGA
AAGTCTTCAAAGTGTACAATGAAGCTGGTGTGACCTTCACATAGATGGATCATGGCTGACTTCCTCACTATCCTCTTCACATGTAACTTC
TGCAGACCTATCACAAGTTTACATGTAACCACAGAAATCCCTTTCTCTCCTGACTCATTAATAATGGATACCATTCTCAACAAGTCAATC

>98588_98588_3_VTI1A-GLUD1_VTI1A_chr10_114298089_ENST00000393077_GLUD1_chr10_88827914_ENST00000544149_length(amino acids)=495AA_BP=152
MAWATRSGAAMSSDFEGYEQDFAVLTAEITSKIARVPRLPPDEKKQMVANVEKQLEEAKELLEQMDLEVREIPPQSRGMYSNRMRSYKQE
MGKLETDFKRSRIAYSDEVRNELLGDDGNSSENQRAHLLDNTERLERSSRRLEAGYQIAVETGPGIDVPAPDMSTGEREMSWIADTYAST
IGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGES
DGSIWNPDGIDPKELEDFKLQHGSILGFPKAKPYEGSILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLERNIM
VIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMSVQESLERKFGKHGGTIPIVPTAEFQDRISGASEKDIVHSGLAYT

--------------------------------------------------------------
>98588_98588_4_VTI1A-GLUD1_VTI1A_chr10_114298089_ENST00000432306_GLUD1_chr10_88827914_ENST00000277865_length(transcript)=2839nt_BP=543nt
CCGTTCTGCTCTCGGGGGCACCTTCCGGGGTTCCTAAGCCGCGGGGCCCCTCGCTGCCCCTCGAGGCCCTTTCCCTGACCTAGGCTTTGG
CCTGGGCTACTCGTTCCGGAGCCGCCATGTCGTCCGACTTCGAAGGTTACGAGCAGGACTTCGCGGTGCTCACTGCAGAGATCACCAGCA
AGATTGCGAGGGTCCCACGACTCCCGCCTGATGAAAAGAAACAGATGGTTGCAAATGTGGAGAAACAGCTTGAAGAAGCGAAAGAACTGC
TTGAACAGATGGATTTGGAAGTCCGAGAGATACCACCCCAAAGTCGAGGGATGTACAGCAACAGAATGAGAAGCTACAAACAAGAAATGG
GAAAACTCGAAACAGATTTTAAAAGGTCACGGATCGCCTACAGTGACGAAGTACGGAATGAGCTCCTGGGGGATGATGGGAATTCCTCAG
AGAACCAGAGGGCACATCTGCTCGATAACACAGAGAGGCTGGAAAGGTCATCTCGGAGACTAGAGGCTGGATACCAAATAGCAGTGGAAA
CCGGTCCTGGCATTGATGTGCCTGCTCCAGACATGAGCACAGGTGAGCGGGAGATGTCCTGGATCGCTGATACCTATGCCAGCACCATAG
GGCACTATGATATTAATGCACACGCCTGTGTTACTGGTAAACCCATCAGCCAAGGGGGAATCCATGGACGCATCTCTGCTACTGGCCGTG
GTGTCTTCCATGGGATTGAAAATTTCATCAATGAAGCTTCTTACATGAGCATTTTAGGAATGACACCAGGGTTTGGAGATAAAACATTTG
TTGTTCAGGGATTTGGTAATGTGGGCCTACACTCTATGAGATATTTACATCGTTTTGGTGCTAAATGTATTGCTGTTGGTGAGTCTGATG
GGAGTATATGGAATCCAGATGGTATTGACCCAAAGGAACTGGAAGACTTCAAATTGCAACATGGGTCCATTCTGGGCTTCCCCAAGGCAA
AGCCCTATGAAGGAAGCATCTTGGAGGCCGACTGTGACATACTGATCCCAGCTGCCAGTGAGAAGCAGTTGACCAAATCCAACGCACCCA
GAGTCAAAGCCAAGATCATTGCTGAAGGTGCCAATGGGCCAACAACTCCAGAAGCTGACAAGATCTTCCTGGAGAGAAACATTATGGTTA
TTCCAGATCTCTACTTGAATGCTGGAGGAGTGACAGTATCTTACTTTGAGTGGCTGAAGAATCTAAATCATGTCAGCTATGGCCGTTTGA
CCTTCAAATATGAAAGGGATTCTAACTACCACTTGCTCATGTCTGTTCAAGAGAGTTTAGAAAGAAAATTTGGAAAGCATGGTGGAACTA
TTCCCATTGTACCCACGGCAGAGTTCCAAGACAGGATATCGGGTGCATCTGAGAAAGACATCGTGCACTCTGGCTTGGCATACACAATGG
AGCGTTCTGCCAGGCAAATTATGCGCACAGCCATGAAGTATAACCTGGGATTGGACCTGAGAACAGCTGCCTATGTTAATGCCATTGAGA
AAGTCTTCAAAGTGTACAATGAAGCTGGTGTGACCTTCACATAGATGGATCATGGCTGACTTCCTCACTATCCTCTTCACATGTAACTTC
TGCAGACCTATCACAAGTTTACATGTAACCACAGAAATCCCTTTCTCTCCTGACTCATTAATAATGGATACCATTCTCAACAAGTCAATC
CAAGTCAGCCCGTTAAGGAGAAAGAAATTAAGGTTAGCGGATCATGTACAAGCTGAGTGTGAAAGTAGAAATCACCTACACCAGAGAGCC
ATTTTGGTATTTTGCCTTTAAATAAAAAGCCTCCTTTATCTGGCTGTGCAGCCTTGCTCTGTGGCTTTTCCCAACACAATCAGTGCTAGT
GCTGGGGAGGAACAGTCAAGAGCAGTCAGTTGCTTGCTTATTTTTTCTGGATGAGTCTGGGACACACTGTAACTTTAACACATTTAAGAA
GTAGGTGTGTGGCCTTTTCAGAAGGTGGCATGGTCCTCAAGTGAGTTCTTAGTATTTTATATCAGCAAAATAATTCAATTTTGCAGGTTG
CAAACAAATATAAAACCTGTTTCTGTTTATGAATATTATTCTTTTAGAATAGAATAAGTACATGCTGCTGTAATAAAATTGCCTTTAATC
ACTTAACAAGCCTAACCTTGACTCAAACAGTGAATGCCTATAGAAATAATAAATGAAAAAAACTAGTATTTTTATATCATAAAACAATGT
CATTTATAGCTTATCATTCATGTATTGTCCAGCAGACATTAAAAGCCCTGTGGATAATTAAGTTATCTTCATACCTGCAAAATGGTGGAG
GCTATTTTCATTAAAACTGTCAGAATTTGCTTACTATAATTATGATACAGTCCAAAGAATGCAGTCACTTTTTATCATGTTAACTAATTG
TTCTCTTTTGAAGATCTATGGTTGACTAATTAAACAATAATTCAAGTAGAGTGTCCCAGAAAAAAACCACTTGGGCTCCCTGTTTGGAGT
CTGGCTGGCTCTGAGCATTGCCAATGGCCCCTACTCACCTGACTTTGTATCCTCTCCTTTTAGAGGCTTTGCATTCTGCACCCAGCTTCA
CTAACAGTGGGCTGAAAACATCCTTGGGTTGAGTGTTTCATTTGGGAGTTATTTGGCCAGGGCCTTTTGAACAGTAGTGTCCCCATGAAG
TGCTAGATAATATATGTGTAAGAGTCAGCTTTTTTTTTTTTTTTAACTCTAACACCCTTCAGAAATTTCTAACTACTTTGTAACTGCATG

>98588_98588_4_VTI1A-GLUD1_VTI1A_chr10_114298089_ENST00000432306_GLUD1_chr10_88827914_ENST00000277865_length(amino acids)=495AA_BP=152
MAWATRSGAAMSSDFEGYEQDFAVLTAEITSKIARVPRLPPDEKKQMVANVEKQLEEAKELLEQMDLEVREIPPQSRGMYSNRMRSYKQE
MGKLETDFKRSRIAYSDEVRNELLGDDGNSSENQRAHLLDNTERLERSSRRLEAGYQIAVETGPGIDVPAPDMSTGEREMSWIADTYAST
IGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGES
DGSIWNPDGIDPKELEDFKLQHGSILGFPKAKPYEGSILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLERNIM
VIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMSVQESLERKFGKHGGTIPIVPTAEFQDRISGASEKDIVHSGLAYT

--------------------------------------------------------------
>98588_98588_5_VTI1A-GLUD1_VTI1A_chr10_114298089_ENST00000432306_GLUD1_chr10_88827914_ENST00000537649_length(transcript)=2835nt_BP=543nt
CCGTTCTGCTCTCGGGGGCACCTTCCGGGGTTCCTAAGCCGCGGGGCCCCTCGCTGCCCCTCGAGGCCCTTTCCCTGACCTAGGCTTTGG
CCTGGGCTACTCGTTCCGGAGCCGCCATGTCGTCCGACTTCGAAGGTTACGAGCAGGACTTCGCGGTGCTCACTGCAGAGATCACCAGCA
AGATTGCGAGGGTCCCACGACTCCCGCCTGATGAAAAGAAACAGATGGTTGCAAATGTGGAGAAACAGCTTGAAGAAGCGAAAGAACTGC
TTGAACAGATGGATTTGGAAGTCCGAGAGATACCACCCCAAAGTCGAGGGATGTACAGCAACAGAATGAGAAGCTACAAACAAGAAATGG
GAAAACTCGAAACAGATTTTAAAAGGTCACGGATCGCCTACAGTGACGAAGTACGGAATGAGCTCCTGGGGGATGATGGGAATTCCTCAG
AGAACCAGAGGGCACATCTGCTCGATAACACAGAGAGGCTGGAAAGGTCATCTCGGAGACTAGAGGCTGGATACCAAATAGCAGTGGAAA
CCGGTCCTGGCATTGATGTGCCTGCTCCAGACATGAGCACAGGTGAGCGGGAGATGTCCTGGATCGCTGATACCTATGCCAGCACCATAG
GGCACTATGATATTAATGCACACGCCTGTGTTACTGGTAAACCCATCAGCCAAGGGGGAATCCATGGACGCATCTCTGCTACTGGCCGTG
GTGTCTTCCATGGGATTGAAAATTTCATCAATGAAGCTTCTTACATGAGCATTTTAGGAATGACACCAGGGTTTGGAGATAAAACATTTG
TTGTTCAGGGATTTGGTAATGTGGGCCTACACTCTATGAGATATTTACATCGTTTTGGTGCTAAATGTATTGCTGTTGGTGAGTCTGATG
GGAGTATATGGAATCCAGATGGTATTGACCCAAAGGAACTGGAAGACTTCAAATTGCAACATGGGTCCATTCTGGGCTTCCCCAAGGCAA
AGCCCTATGAAGGAAGCATCTTGGAGGCCGACTGTGACATACTGATCCCAGCTGCCAGTGAGAAGCAGTTGACCAAATCCAACGCACCCA
GAGTCAAAGCCAAGATCATTGCTGAAGGTGCCAATGGGCCAACAACTCCAGAAGCTGACAAGATCTTCCTGGAGAGAAACATTATGGTTA
TTCCAGATCTCTACTTGAATGCTGGAGGAGTGACAGTATCTTACTTTGAGTGGCTGAAGAATCTAAATCATGTCAGCTATGGCCGTTTGA
CCTTCAAATATGAAAGGGATTCTAACTACCACTTGCTCATGTCTGTTCAAGAGAGTTTAGAAAGAAAATTTGGAAAGCATGGTGGAACTA
TTCCCATTGTACCCACGGCAGAGTTCCAAGACAGGATATCGGGTGCATCTGAGAAAGACATCGTGCACTCTGGCTTGGCATACACAATGG
AGCGTTCTGCCAGGCAAATTATGCGCACAGCCATGAAGTATAACCTGGGATTGGACCTGAGAACAGCTGCCTATGTTAATGCCATTGAGA
AAGTCTTCAAAGTGTACAATGAAGCTGGTGTGACCTTCACATAGATGGATCATGGCTGACTTCCTCACTATCCTCTTCACATGTAACTTC
TGCAGACCTATCACAAGTTTACATGTAACCACAGAAATCCCTTTCTCTCCTGACTCATTAATAATGGATACCATTCTCAACAAGTCAATC
CAAGTCAGCCCGTTAAGGAGAAAGAAATTAAGGTTAGCGGATCATGTACAAGCTGAGTGTGAAAGTAGAAATCACCTACACCAGAGAGCC
ATTTTGGTATTTTGCCTTTAAATAAAAAGCCTCCTTTATCTGGCTGTGCAGCCTTGCTCTGTGGCTTTTCCCAACACAATCAGTGCTAGT
GCTGGGGAGGAACAGTCAAGAGCAGTCAGTTGCTTGCTTATTTTTTCTGGATGAGTCTGGGACACACTGTAACTTTAACACATTTAAGAA
GTAGGTGTGTGGCCTTTTCAGAAGGTGGCATGGTCCTCAAGTGAGTTCTTAGTATTTTATATCAGCAAAATAATTCAATTTTGCAGGTTG
CAAACAAATATAAAACCTGTTTCTGTTTATGAATATTATTCTTTTAGAATAGAATAAGTACATGCTGCTGTAATAAAATTGCCTTTAATC
ACTTAACAAGCCTAACCTTGACTCAAACAGTGAATGCCTATAGAAATAATAAATGAAAAAAACTAGTATTTTTATATCATAAAACAATGT
CATTTATAGCTTATCATTCATGTATTGTCCAGCAGACATTAAAAGCCCTGTGGATAATTAAGTTATCTTCATACCTGCAAAATGGTGGAG
GCTATTTTCATTAAAACTGTCAGAATTTGCTTACTATAATTATGATACAGTCCAAAGAATGCAGTCACTTTTTATCATGTTAACTAATTG
TTCTCTTTTGAAGATCTATGGTTGACTAATTAAACAATAATTCAAGTAGAGTGTCCCAGAAAAAAACCACTTGGGCTCCCTGTTTGGAGT
CTGGCTGGCTCTGAGCATTGCCAATGGCCCCTACTCACCTGACTTTGTATCCTCTCCTTTTAGAGGCTTTGCATTCTGCACCCAGCTTCA
CTAACAGTGGGCTGAAAACATCCTTGGGTTGAGTGTTTCATTTGGGAGTTATTTGGCCAGGGCCTTTTGAACAGTAGTGTCCCCATGAAG
TGCTAGATAATATATGTGTAAGAGTCAGCTTTTTTTTTTTTTTTAACTCTAACACCCTTCAGAAATTTCTAACTACTTTGTAACTGCATG

>98588_98588_5_VTI1A-GLUD1_VTI1A_chr10_114298089_ENST00000432306_GLUD1_chr10_88827914_ENST00000537649_length(amino acids)=495AA_BP=152
MAWATRSGAAMSSDFEGYEQDFAVLTAEITSKIARVPRLPPDEKKQMVANVEKQLEEAKELLEQMDLEVREIPPQSRGMYSNRMRSYKQE
MGKLETDFKRSRIAYSDEVRNELLGDDGNSSENQRAHLLDNTERLERSSRRLEAGYQIAVETGPGIDVPAPDMSTGEREMSWIADTYAST
IGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGES
DGSIWNPDGIDPKELEDFKLQHGSILGFPKAKPYEGSILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLERNIM
VIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMSVQESLERKFGKHGGTIPIVPTAEFQDRISGASEKDIVHSGLAYT

--------------------------------------------------------------
>98588_98588_6_VTI1A-GLUD1_VTI1A_chr10_114298089_ENST00000432306_GLUD1_chr10_88827914_ENST00000544149_length(transcript)=1724nt_BP=543nt
CCGTTCTGCTCTCGGGGGCACCTTCCGGGGTTCCTAAGCCGCGGGGCCCCTCGCTGCCCCTCGAGGCCCTTTCCCTGACCTAGGCTTTGG
CCTGGGCTACTCGTTCCGGAGCCGCCATGTCGTCCGACTTCGAAGGTTACGAGCAGGACTTCGCGGTGCTCACTGCAGAGATCACCAGCA
AGATTGCGAGGGTCCCACGACTCCCGCCTGATGAAAAGAAACAGATGGTTGCAAATGTGGAGAAACAGCTTGAAGAAGCGAAAGAACTGC
TTGAACAGATGGATTTGGAAGTCCGAGAGATACCACCCCAAAGTCGAGGGATGTACAGCAACAGAATGAGAAGCTACAAACAAGAAATGG
GAAAACTCGAAACAGATTTTAAAAGGTCACGGATCGCCTACAGTGACGAAGTACGGAATGAGCTCCTGGGGGATGATGGGAATTCCTCAG
AGAACCAGAGGGCACATCTGCTCGATAACACAGAGAGGCTGGAAAGGTCATCTCGGAGACTAGAGGCTGGATACCAAATAGCAGTGGAAA
CCGGTCCTGGCATTGATGTGCCTGCTCCAGACATGAGCACAGGTGAGCGGGAGATGTCCTGGATCGCTGATACCTATGCCAGCACCATAG
GGCACTATGATATTAATGCACACGCCTGTGTTACTGGTAAACCCATCAGCCAAGGGGGAATCCATGGACGCATCTCTGCTACTGGCCGTG
GTGTCTTCCATGGGATTGAAAATTTCATCAATGAAGCTTCTTACATGAGCATTTTAGGAATGACACCAGGGTTTGGAGATAAAACATTTG
TTGTTCAGGGATTTGGTAATGTGGGCCTACACTCTATGAGATATTTACATCGTTTTGGTGCTAAATGTATTGCTGTTGGTGAGTCTGATG
GGAGTATATGGAATCCAGATGGTATTGACCCAAAGGAACTGGAAGACTTCAAATTGCAACATGGGTCCATTCTGGGCTTCCCCAAGGCAA
AGCCCTATGAAGGAAGCATCTTGGAGGCCGACTGTGACATACTGATCCCAGCTGCCAGTGAGAAGCAGTTGACCAAATCCAACGCACCCA
GAGTCAAAGCCAAGATCATTGCTGAAGGTGCCAATGGGCCAACAACTCCAGAAGCTGACAAGATCTTCCTGGAGAGAAACATTATGGTTA
TTCCAGATCTCTACTTGAATGCTGGAGGAGTGACAGTATCTTACTTTGAGTGGCTGAAGAATCTAAATCATGTCAGCTATGGCCGTTTGA
CCTTCAAATATGAAAGGGATTCTAACTACCACTTGCTCATGTCTGTTCAAGAGAGTTTAGAAAGAAAATTTGGAAAGCATGGTGGAACTA
TTCCCATTGTACCCACGGCAGAGTTCCAAGACAGGATATCGGGTGCATCTGAGAAAGACATCGTGCACTCTGGCTTGGCATACACAATGG
AGCGTTCTGCCAGGCAAATTATGCGCACAGCCATGAAGTATAACCTGGGATTGGACCTGAGAACAGCTGCCTATGTTAATGCCATTGAGA
AAGTCTTCAAAGTGTACAATGAAGCTGGTGTGACCTTCACATAGATGGATCATGGCTGACTTCCTCACTATCCTCTTCACATGTAACTTC
TGCAGACCTATCACAAGTTTACATGTAACCACAGAAATCCCTTTCTCTCCTGACTCATTAATAATGGATACCATTCTCAACAAGTCAATC

>98588_98588_6_VTI1A-GLUD1_VTI1A_chr10_114298089_ENST00000432306_GLUD1_chr10_88827914_ENST00000544149_length(amino acids)=495AA_BP=152
MAWATRSGAAMSSDFEGYEQDFAVLTAEITSKIARVPRLPPDEKKQMVANVEKQLEEAKELLEQMDLEVREIPPQSRGMYSNRMRSYKQE
MGKLETDFKRSRIAYSDEVRNELLGDDGNSSENQRAHLLDNTERLERSSRRLEAGYQIAVETGPGIDVPAPDMSTGEREMSWIADTYAST
IGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGES
DGSIWNPDGIDPKELEDFKLQHGSILGFPKAKPYEGSILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLERNIM
VIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMSVQESLERKFGKHGGTIPIVPTAEFQDRISGASEKDIVHSGLAYT

--------------------------------------------------------------

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Fusion Gene PPI Analysis for VTI1A-GLUD1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for VTI1A-GLUD1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for VTI1A-GLUD1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource