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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:WAC-APBB1IP (FusionGDB2 ID:98660)

Fusion Gene Summary for WAC-APBB1IP

check button Fusion gene summary
Fusion gene informationFusion gene name: WAC-APBB1IP
Fusion gene ID: 98660
HgeneTgene
Gene symbol

WAC

APBB1IP

Gene ID

51322

54518

Gene nameWW domain containing adaptor with coiled-coilamyloid beta precursor protein binding family B member 1 interacting protein
SynonymsBM-016|DESSH|PRO1741|Wwp4INAG1|PREL1|RARP1|RIAM
Cytomap

10p12.1|10p12.1-p11.2

10p12.1

Type of geneprotein-codingprotein-coding
DescriptionWW domain-containing adapter protein with coiled-coilamyloid beta A4 precursor protein-binding family B member 1-interacting proteinAPBB1-interacting protein 1PREL-1RARP-1Rap1-GTP-interacting adaptor moleculeRap1-interacting adaptor moleculeproline rich EVH1 ligand 1proline-rich protein 73rap1-GTP-i
Modification date2020031320200313
UniProtAcc.

Q7Z5R6

Ensembl transtripts involved in fusion geneENST00000532233, ENST00000347934, 
ENST00000354911, ENST00000375646, 
ENST00000375664, ENST00000428935, 
ENST00000376236, ENST00000356785, 
ENST00000493857, 
Fusion gene scores* DoF score17 X 16 X 8=21766 X 9 X 5=270
# samples 227
** MAII scorelog2(22/2176*10)=-3.30610312772568
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(7/270*10)=-1.94753258010586
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: WAC [Title/Abstract] AND APBB1IP [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointWAC(28824686)-APBB1IP(26849034), # samples:2
WAC(28872434)-APBB1IP(26855890), # samples:2
APBB1IP(26727782)-WAC(28897115), # samples:1
Anticipated loss of major functional domain due to fusion event.WAC-APBB1IP seems lost the major protein functional domain in Hgene partner, which is a epigenetic factor due to the frame-shifted ORF.
WAC-APBB1IP seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across WAC (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across APBB1IP (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-AO-A0JI-01AWACchr10

28824685

+APBB1IPchr10

26849033

+
ChimerDB4BRCATCGA-AO-A0JI-01AWACchr10

28824686

-APBB1IPchr10

26849034

+
ChimerDB4BRCATCGA-AO-A0JI-01AWACchr10

28824686

+APBB1IPchr10

26849034

+
ChimerDB4BRCATCGA-E9-A1NA-01AWACchr10

28872434

-APBB1IPchr10

26855890

+
ChimerDB4BRCATCGA-E9-A1NA-01AWACchr10

28872434

+APBB1IPchr10

26855890

+
ChimerDB4BRCATCGA-E9-A1NA-01AWACchr10

28872436

+APBB1IPchr10

26855885

+


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Fusion Gene ORF analysis for WAC-APBB1IP

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000532233ENST00000376236WACchr10

28824685

+APBB1IPchr10

26849033

+
3UTR-3CDSENST00000532233ENST00000376236WACchr10

28824686

+APBB1IPchr10

26849034

+
3UTR-intronENST00000532233ENST00000356785WACchr10

28824685

+APBB1IPchr10

26849033

+
3UTR-intronENST00000532233ENST00000356785WACchr10

28824686

+APBB1IPchr10

26849034

+
3UTR-intronENST00000532233ENST00000493857WACchr10

28824685

+APBB1IPchr10

26849033

+
3UTR-intronENST00000532233ENST00000493857WACchr10

28824686

+APBB1IPchr10

26849034

+
5CDS-3UTRENST00000347934ENST00000493857WACchr10

28872434

+APBB1IPchr10

26855890

+
5CDS-3UTRENST00000347934ENST00000493857WACchr10

28872436

+APBB1IPchr10

26855885

+
5CDS-3UTRENST00000354911ENST00000493857WACchr10

28872434

+APBB1IPchr10

26855890

+
5CDS-3UTRENST00000354911ENST00000493857WACchr10

28872436

+APBB1IPchr10

26855885

+
5CDS-3UTRENST00000375646ENST00000493857WACchr10

28872434

+APBB1IPchr10

26855890

+
5CDS-3UTRENST00000375646ENST00000493857WACchr10

28872436

+APBB1IPchr10

26855885

+
5CDS-3UTRENST00000375664ENST00000493857WACchr10

28872434

+APBB1IPchr10

26855890

+
5CDS-3UTRENST00000375664ENST00000493857WACchr10

28872436

+APBB1IPchr10

26855885

+
5CDS-3UTRENST00000428935ENST00000493857WACchr10

28872434

+APBB1IPchr10

26855890

+
5CDS-3UTRENST00000428935ENST00000493857WACchr10

28872436

+APBB1IPchr10

26855885

+
5CDS-intronENST00000347934ENST00000356785WACchr10

28824685

+APBB1IPchr10

26849033

+
5CDS-intronENST00000347934ENST00000356785WACchr10

28824686

+APBB1IPchr10

26849034

+
5CDS-intronENST00000347934ENST00000356785WACchr10

28872434

+APBB1IPchr10

26855890

+
5CDS-intronENST00000347934ENST00000356785WACchr10

28872436

+APBB1IPchr10

26855885

+
5CDS-intronENST00000347934ENST00000493857WACchr10

28824685

+APBB1IPchr10

26849033

+
5CDS-intronENST00000347934ENST00000493857WACchr10

28824686

+APBB1IPchr10

26849034

+
5CDS-intronENST00000354911ENST00000356785WACchr10

28824685

+APBB1IPchr10

26849033

+
5CDS-intronENST00000354911ENST00000356785WACchr10

28824686

+APBB1IPchr10

26849034

+
5CDS-intronENST00000354911ENST00000356785WACchr10

28872434

+APBB1IPchr10

26855890

+
5CDS-intronENST00000354911ENST00000356785WACchr10

28872436

+APBB1IPchr10

26855885

+
5CDS-intronENST00000354911ENST00000493857WACchr10

28824685

+APBB1IPchr10

26849033

+
5CDS-intronENST00000354911ENST00000493857WACchr10

28824686

+APBB1IPchr10

26849034

+
5CDS-intronENST00000375646ENST00000356785WACchr10

28824685

+APBB1IPchr10

26849033

+
5CDS-intronENST00000375646ENST00000356785WACchr10

28824686

+APBB1IPchr10

26849034

+
5CDS-intronENST00000375646ENST00000356785WACchr10

28872434

+APBB1IPchr10

26855890

+
5CDS-intronENST00000375646ENST00000356785WACchr10

28872436

+APBB1IPchr10

26855885

+
5CDS-intronENST00000375646ENST00000493857WACchr10

28824685

+APBB1IPchr10

26849033

+
5CDS-intronENST00000375646ENST00000493857WACchr10

28824686

+APBB1IPchr10

26849034

+
5CDS-intronENST00000375664ENST00000356785WACchr10

28824685

+APBB1IPchr10

26849033

+
5CDS-intronENST00000375664ENST00000356785WACchr10

28824686

+APBB1IPchr10

26849034

+
5CDS-intronENST00000375664ENST00000356785WACchr10

28872434

+APBB1IPchr10

26855890

+
5CDS-intronENST00000375664ENST00000356785WACchr10

28872436

+APBB1IPchr10

26855885

+
5CDS-intronENST00000375664ENST00000493857WACchr10

28824685

+APBB1IPchr10

26849033

+
5CDS-intronENST00000375664ENST00000493857WACchr10

28824686

+APBB1IPchr10

26849034

+
5CDS-intronENST00000428935ENST00000356785WACchr10

28824685

+APBB1IPchr10

26849033

+
5CDS-intronENST00000428935ENST00000356785WACchr10

28824686

+APBB1IPchr10

26849034

+
5CDS-intronENST00000428935ENST00000356785WACchr10

28872434

+APBB1IPchr10

26855890

+
5CDS-intronENST00000428935ENST00000356785WACchr10

28872436

+APBB1IPchr10

26855885

+
5CDS-intronENST00000428935ENST00000493857WACchr10

28824685

+APBB1IPchr10

26849033

+
5CDS-intronENST00000428935ENST00000493857WACchr10

28824686

+APBB1IPchr10

26849034

+
Frame-shiftENST00000347934ENST00000376236WACchr10

28824685

+APBB1IPchr10

26849033

+
Frame-shiftENST00000347934ENST00000376236WACchr10

28824686

+APBB1IPchr10

26849034

+
Frame-shiftENST00000354911ENST00000376236WACchr10

28824685

+APBB1IPchr10

26849033

+
Frame-shiftENST00000354911ENST00000376236WACchr10

28824686

+APBB1IPchr10

26849034

+
Frame-shiftENST00000375646ENST00000376236WACchr10

28824685

+APBB1IPchr10

26849033

+
Frame-shiftENST00000375646ENST00000376236WACchr10

28824686

+APBB1IPchr10

26849034

+
Frame-shiftENST00000375664ENST00000376236WACchr10

28824685

+APBB1IPchr10

26849033

+
Frame-shiftENST00000375664ENST00000376236WACchr10

28824686

+APBB1IPchr10

26849034

+
Frame-shiftENST00000428935ENST00000376236WACchr10

28824685

+APBB1IPchr10

26849033

+
Frame-shiftENST00000428935ENST00000376236WACchr10

28824686

+APBB1IPchr10

26849034

+
In-frameENST00000347934ENST00000376236WACchr10

28872434

+APBB1IPchr10

26855890

+
In-frameENST00000347934ENST00000376236WACchr10

28872436

+APBB1IPchr10

26855885

+
In-frameENST00000354911ENST00000376236WACchr10

28872434

+APBB1IPchr10

26855890

+
In-frameENST00000354911ENST00000376236WACchr10

28872436

+APBB1IPchr10

26855885

+
In-frameENST00000375646ENST00000376236WACchr10

28872434

+APBB1IPchr10

26855890

+
In-frameENST00000375646ENST00000376236WACchr10

28872436

+APBB1IPchr10

26855885

+
In-frameENST00000375664ENST00000376236WACchr10

28872434

+APBB1IPchr10

26855890

+
In-frameENST00000375664ENST00000376236WACchr10

28872436

+APBB1IPchr10

26855885

+
In-frameENST00000428935ENST00000376236WACchr10

28872434

+APBB1IPchr10

26855890

+
In-frameENST00000428935ENST00000376236WACchr10

28872436

+APBB1IPchr10

26855885

+
intron-3CDSENST00000532233ENST00000376236WACchr10

28872434

+APBB1IPchr10

26855890

+
intron-3CDSENST00000532233ENST00000376236WACchr10

28872436

+APBB1IPchr10

26855885

+
intron-3UTRENST00000532233ENST00000493857WACchr10

28872434

+APBB1IPchr10

26855890

+
intron-3UTRENST00000532233ENST00000493857WACchr10

28872436

+APBB1IPchr10

26855885

+
intron-intronENST00000532233ENST00000356785WACchr10

28872434

+APBB1IPchr10

26855890

+
intron-intronENST00000532233ENST00000356785WACchr10

28872436

+APBB1IPchr10

26855885

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000375664WACchr1028872434+ENST00000376236APBB1IPchr1026855890+16988554571347296
ENST00000375646WACchr1028872434+ENST00000376236APBB1IPchr1026855890+14075641661056296
ENST00000347934WACchr1028872434+ENST00000376236APBB1IPchr1026855890+14916481711175334
ENST00000354911WACchr1028872434+ENST00000376236APBB1IPchr1026855890+1385542651069334
ENST00000428935WACchr1028872434+ENST00000376236APBB1IPchr1026855890+130946616993325
ENST00000375664WACchr1028872436+ENST00000376236APBB1IPchr1026855885+16988554571347296
ENST00000375646WACchr1028872436+ENST00000376236APBB1IPchr1026855885+14075641661056296
ENST00000347934WACchr1028872436+ENST00000376236APBB1IPchr1026855885+14916481711175334
ENST00000354911WACchr1028872436+ENST00000376236APBB1IPchr1026855885+1385542651069334
ENST00000428935WACchr1028872436+ENST00000376236APBB1IPchr1026855885+130946616993325

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000375664ENST00000376236WACchr1028872434+APBB1IPchr1026855890+0.0356805850.9643194
ENST00000375646ENST00000376236WACchr1028872434+APBB1IPchr1026855890+0.0350999240.9649001
ENST00000347934ENST00000376236WACchr1028872434+APBB1IPchr1026855890+0.027655220.97234476
ENST00000354911ENST00000376236WACchr1028872434+APBB1IPchr1026855890+0.0262147240.9737853
ENST00000428935ENST00000376236WACchr1028872434+APBB1IPchr1026855890+0.024362460.97563756
ENST00000375664ENST00000376236WACchr1028872436+APBB1IPchr1026855885+0.0356805850.9643194
ENST00000375646ENST00000376236WACchr1028872436+APBB1IPchr1026855885+0.0350999240.9649001
ENST00000347934ENST00000376236WACchr1028872436+APBB1IPchr1026855885+0.027655220.97234476
ENST00000354911ENST00000376236WACchr1028872436+APBB1IPchr1026855885+0.0262147240.9737853
ENST00000428935ENST00000376236WACchr1028872436+APBB1IPchr1026855885+0.024362460.97563756

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Fusion Genomic Features for WAC-APBB1IP


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
WACchr1028824686+APBB1IPchr1026849033+0.0009086960.99909127
WACchr1028872434+APBB1IPchr1026855889+1.59E-050.99998415
WACchr1028824686+APBB1IPchr1026849033+0.0009086960.99909127
WACchr1028872434+APBB1IPchr1026855889+1.59E-050.99998415

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for WAC-APBB1IP


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr10:28824686/chr10:26849034)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.APBB1IP

Q7Z5R6

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Appears to function in the signal transduction from Ras activation to actin cytoskeletal remodeling. Suppresses insulin-induced promoter activities through AP1 and SRE. Mediates Rap1-induced adhesion. {ECO:0000269|PubMed:14530287, ECO:0000269|PubMed:15469846}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneAPBB1IPchr10:28872434chr10:26855890ENST000003762361315503_640491667.0Compositional biasNote=Pro-rich
TgeneAPBB1IPchr10:28872436chr10:26855885ENST000003762361315503_640491667.0Compositional biasNote=Pro-rich

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneWACchr10:28872434chr10:26855890ENST00000347934+413618_644127545.0Coiled coilOntology_term=ECO:0000255
HgeneWACchr10:28872434chr10:26855890ENST00000354911+414618_644127648.0Coiled coilOntology_term=ECO:0000255
HgeneWACchr10:28872434chr10:26855890ENST00000375664+414618_64482603.0Coiled coilOntology_term=ECO:0000255
HgeneWACchr10:28872434chr10:26855890ENST00000428935+410618_64482437.0Coiled coilOntology_term=ECO:0000255
HgeneWACchr10:28872436chr10:26855885ENST00000347934+413618_644127545.0Coiled coilOntology_term=ECO:0000255
HgeneWACchr10:28872436chr10:26855885ENST00000354911+414618_644127648.0Coiled coilOntology_term=ECO:0000255
HgeneWACchr10:28872436chr10:26855885ENST00000375664+414618_64482603.0Coiled coilOntology_term=ECO:0000255
HgeneWACchr10:28872436chr10:26855885ENST00000428935+410618_64482437.0Coiled coilOntology_term=ECO:0000255
HgeneWACchr10:28872434chr10:26855890ENST00000347934+413129_162127545.0DomainWW
HgeneWACchr10:28872434chr10:26855890ENST00000354911+414129_162127648.0DomainWW
HgeneWACchr10:28872434chr10:26855890ENST00000375664+414129_16282603.0DomainWW
HgeneWACchr10:28872434chr10:26855890ENST00000428935+410129_16282437.0DomainWW
HgeneWACchr10:28872436chr10:26855885ENST00000347934+413129_162127545.0DomainWW
HgeneWACchr10:28872436chr10:26855885ENST00000354911+414129_162127648.0DomainWW
HgeneWACchr10:28872436chr10:26855885ENST00000375664+414129_16282603.0DomainWW
HgeneWACchr10:28872436chr10:26855885ENST00000428935+410129_16282437.0DomainWW
TgeneAPBB1IPchr10:28872434chr10:26855890ENST000003762361315129_148491667.0Compositional biasNote=Pro-rich
TgeneAPBB1IPchr10:28872434chr10:26855890ENST000003762361315152_155491667.0Compositional biasNote=Poly-Glu
TgeneAPBB1IPchr10:28872436chr10:26855885ENST000003762361315129_148491667.0Compositional biasNote=Pro-rich
TgeneAPBB1IPchr10:28872436chr10:26855885ENST000003762361315152_155491667.0Compositional biasNote=Poly-Glu
TgeneAPBB1IPchr10:28872434chr10:26855890ENST000003762361315176_263491667.0DomainRas-associating
TgeneAPBB1IPchr10:28872434chr10:26855890ENST000003762361315310_419491667.0DomainPH
TgeneAPBB1IPchr10:28872436chr10:26855885ENST000003762361315176_263491667.0DomainRas-associating
TgeneAPBB1IPchr10:28872436chr10:26855885ENST000003762361315310_419491667.0DomainPH


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Fusion Gene Sequence for WAC-APBB1IP


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>98660_98660_1_WAC-APBB1IP_WAC_chr10_28872434_ENST00000347934_APBB1IP_chr10_26855890_ENST00000376236_length(transcript)=1491nt_BP=648nt
CGTCGTCTTGCCCCCCTCCCCCCGGTTCGCGGTGCCGCCGTGTAGTTGGCGCCGCTGCCCCGGCTGAGAGTGAGCGTGGTGTCGACGGAG
GGAGATGGCCCGGGAGCGCCGGCGCCAGTAACTGGGAGCTGATGAGAGTCGCCGAGGGCGCGCCGGGCCCAGGTGCCGGGGCTGCCCGCC
GCCCGCCGCCGCCGCCGCCTGCGCGCCCGCCCGCCTTTCGCGGCCGCTCTCCCCCCTCCCCGACACACACTCACAGGCCGGGCATTGATG
GTAATGTATGCGAGGAAACAGCAGAGACTCAGTGATGGCTGTCACGACCGGAGGGGGGACTCGCAGCCTTACCAGGCACTTAAGTATTCA
TCGAAGAGTCACCCCAGTAGCGGTGATCACAGACATGAAAAGATGCGAGACGCCGGAGATCCTTCACCACCAAATAAAATGTTGCGGAGA
TCTGATAGTCCTGAAAACAAATACAGTGACAGCACAGGTCACAGTAAGGCCAAAAATGTGCATACTCACAGAGTTAGAGAGAGGGATGGT
GGGACCAGTTACTCTCCACAAGAAAATTCACACAACCACAGTGCTCTTCATAGTTCAAATTCACATTCTTCTAATCCAAGCAATAACCCA
AGCAAAACTTCAGATGCAGATAAGAAGCCAGCCCTCGGGAACCACCACGACCCGGCAGTGCCCCGGGCCCCGCACGCCCCCAAGTCCAGC
CTGCCCCCGCCCCCTCCGGTGCGGAGGTCCTCCGACACCAGCGGCAGTCCCGCCACGCCCCTCAAGGCCAAGGGCACAGGCGGCGGGGGC
TTGCCCGCCCCACCCGACGACTTCCTGCCGCCGCCGCCACCGCCGCCGCCCCTCGATGACCCTGAGCTCCCGCCGCCGCCCCCGGACTTC
ATGGAGCCGCCCCCAGACTTCGTGCCCCCGCCCCCGCCGTCGTACGCAGGGATCGCGGGCTCAGAGCTGCCCCCGCCGCCGCCGCCGCCG
CCCGCGCCCGCGCCCGCCCCCGTCCCCGACTCCGCCAGGCCGCCCCCCGCGGTGGCCAAGAGGCCTCCTGTGCCCCCCAAGAGGCAAGAG
AACCCAGGGCACCCCGGCGGAGCAGGAGGCGGGGAGCAAGATTTCATGTCAGACCTCATGAAAGCTTTGCAAAAGAAGAGAGGCAACGTG
TCCTAGGGACGGGCATGATGAGTGTTCCAGAGGGAGAAGCATCGCTGACCCCGAGCGCAGGTTTTGCTAGCAGATTGCCCTGACATCTTG
TTCATTTCAGATAAAATGTGATGGGAAACTTCTCACTGATGTGCTCAAGTACAGGCATAACCATTAACCCAGTAGAGTTCAGAATATCTG
CCCAAATGTACATATCGTTCCCATGTATTTTAACCTAAATGGAATGTATCTTCCCTTCCAAGCTGCCTAAAGCGCTGTTTTAGGTTCATT

>98660_98660_1_WAC-APBB1IP_WAC_chr10_28872434_ENST00000347934_APBB1IP_chr10_26855890_ENST00000376236_length(amino acids)=334AA_BP=159
MPAARRRRRLRARPPFAAALPPPRHTLTGRALMVMYARKQQRLSDGCHDRRGDSQPYQALKYSSKSHPSSGDHRHEKMRDAGDPSPPNKM
LRRSDSPENKYSDSTGHSKAKNVHTHRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTSDADKKPALGNHHDPAVPRAPHAP
KSSLPPPPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPDDFLPPPPPPPPLDDPELPPPPPDFMEPPPDFVPPPPPSYAGIAGSELPPPP

--------------------------------------------------------------
>98660_98660_2_WAC-APBB1IP_WAC_chr10_28872434_ENST00000354911_APBB1IP_chr10_26855890_ENST00000376236_length(transcript)=1385nt_BP=542nt
CGCCGGCGCCAGTAACTGGGAGCTGATGAGAGTCGCCGAGGGCGCGCCGGGCCCAGGTGCCGGGGCTGCCCGCCGCCCGCCGCCGCCGCC
GCCTGCGCGCCCGCCCGCCTTTCGCGGCCGCTCTCCCCCCTCCCCGACACACACTCACAGGCCGGGCATTGATGGTAATGTATGCGAGGA
AACAGCAGAGACTCAGTGATGGCTGTCACGACCGGAGGGGGGACTCGCAGCCTTACCAGGCACTTAAGTATTCATCGAAGAGTCACCCCA
GTAGCGGTGATCACAGACATGAAAAGATGCGAGACGCCGGAGATCCTTCACCACCAAATAAAATGTTGCGGAGATCTGATAGTCCTGAAA
ACAAATACAGTGACAGCACAGGTCACAGTAAGGCCAAAAATGTGCATACTCACAGAGTTAGAGAGAGGGATGGTGGGACCAGTTACTCTC
CACAAGAAAATTCACACAACCACAGTGCTCTTCATAGTTCAAATTCACATTCTTCTAATCCAAGCAATAACCCAAGCAAAACTTCAGATG
CAGATAAGAAGCCAGCCCTCGGGAACCACCACGACCCGGCAGTGCCCCGGGCCCCGCACGCCCCCAAGTCCAGCCTGCCCCCGCCCCCTC
CGGTGCGGAGGTCCTCCGACACCAGCGGCAGTCCCGCCACGCCCCTCAAGGCCAAGGGCACAGGCGGCGGGGGCTTGCCCGCCCCACCCG
ACGACTTCCTGCCGCCGCCGCCACCGCCGCCGCCCCTCGATGACCCTGAGCTCCCGCCGCCGCCCCCGGACTTCATGGAGCCGCCCCCAG
ACTTCGTGCCCCCGCCCCCGCCGTCGTACGCAGGGATCGCGGGCTCAGAGCTGCCCCCGCCGCCGCCGCCGCCGCCCGCGCCCGCGCCCG
CCCCCGTCCCCGACTCCGCCAGGCCGCCCCCCGCGGTGGCCAAGAGGCCTCCTGTGCCCCCCAAGAGGCAAGAGAACCCAGGGCACCCCG
GCGGAGCAGGAGGCGGGGAGCAAGATTTCATGTCAGACCTCATGAAAGCTTTGCAAAAGAAGAGAGGCAACGTGTCCTAGGGACGGGCAT
GATGAGTGTTCCAGAGGGAGAAGCATCGCTGACCCCGAGCGCAGGTTTTGCTAGCAGATTGCCCTGACATCTTGTTCATTTCAGATAAAA
TGTGATGGGAAACTTCTCACTGATGTGCTCAAGTACAGGCATAACCATTAACCCAGTAGAGTTCAGAATATCTGCCCAAATGTACATATC
GTTCCCATGTATTTTAACCTAAATGGAATGTATCTTCCCTTCCAAGCTGCCTAAAGCGCTGTTTTAGGTTCATTTATTTTATTATGTTCA

>98660_98660_2_WAC-APBB1IP_WAC_chr10_28872434_ENST00000354911_APBB1IP_chr10_26855890_ENST00000376236_length(amino acids)=334AA_BP=159
MPAARRRRRLRARPPFAAALPPPRHTLTGRALMVMYARKQQRLSDGCHDRRGDSQPYQALKYSSKSHPSSGDHRHEKMRDAGDPSPPNKM
LRRSDSPENKYSDSTGHSKAKNVHTHRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTSDADKKPALGNHHDPAVPRAPHAP
KSSLPPPPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPDDFLPPPPPPPPLDDPELPPPPPDFMEPPPDFVPPPPPSYAGIAGSELPPPP

--------------------------------------------------------------
>98660_98660_3_WAC-APBB1IP_WAC_chr10_28872434_ENST00000375646_APBB1IP_chr10_26855890_ENST00000376236_length(transcript)=1407nt_BP=564nt
GCGATGGCTTCCCTCGCGCCCCACCGTCCTCTTCCGGAAGGCGGCTCCCTCCCTGCGCAGCCCGGAGCCCCTGAGATCAGCCTCGAGCAG
GCGCCCGAGCGAGACTATCCCTAAACGGGAACGGCGGTGGCCGACTCGCGAGTGAGGAAAAGAAGGAAAGGGCAGACTGGTCGCGAAGAG
AAGATCCAGGCCTCAGAGGAGGAGAAAGGCCGGAGCCAGCCGAGCTGTCACGACCGGAGGGGGGACTCGCAGCCTTACCAGGCACTTAAG
TATTCATCGAAGAGTCACCCCAGTAGCGGTGATCACAGACATGAAAAGATGCGAGACGCCGGAGATCCTTCACCACCAAATAAAATGTTG
CGGAGATCTGATAGTCCTGAAAACAAATACAGTGACAGCACAGGTCACAGTAAGGCCAAAAATGTGCATACTCACAGAGTTAGAGAGAGG
GATGGTGGGACCAGTTACTCTCCACAAGAAAATTCACACAACCACAGTGCTCTTCATAGTTCAAATTCACATTCTTCTAATCCAAGCAAT
AACCCAAGCAAAACTTCAGATGCAGATAAGAAGCCAGCCCTCGGGAACCACCACGACCCGGCAGTGCCCCGGGCCCCGCACGCCCCCAAG
TCCAGCCTGCCCCCGCCCCCTCCGGTGCGGAGGTCCTCCGACACCAGCGGCAGTCCCGCCACGCCCCTCAAGGCCAAGGGCACAGGCGGC
GGGGGCTTGCCCGCCCCACCCGACGACTTCCTGCCGCCGCCGCCACCGCCGCCGCCCCTCGATGACCCTGAGCTCCCGCCGCCGCCCCCG
GACTTCATGGAGCCGCCCCCAGACTTCGTGCCCCCGCCCCCGCCGTCGTACGCAGGGATCGCGGGCTCAGAGCTGCCCCCGCCGCCGCCG
CCGCCGCCCGCGCCCGCGCCCGCCCCCGTCCCCGACTCCGCCAGGCCGCCCCCCGCGGTGGCCAAGAGGCCTCCTGTGCCCCCCAAGAGG
CAAGAGAACCCAGGGCACCCCGGCGGAGCAGGAGGCGGGGAGCAAGATTTCATGTCAGACCTCATGAAAGCTTTGCAAAAGAAGAGAGGC
AACGTGTCCTAGGGACGGGCATGATGAGTGTTCCAGAGGGAGAAGCATCGCTGACCCCGAGCGCAGGTTTTGCTAGCAGATTGCCCTGAC
ATCTTGTTCATTTCAGATAAAATGTGATGGGAAACTTCTCACTGATGTGCTCAAGTACAGGCATAACCATTAACCCAGTAGAGTTCAGAA
TATCTGCCCAAATGTACATATCGTTCCCATGTATTTTAACCTAAATGGAATGTATCTTCCCTTCCAAGCTGCCTAAAGCGCTGTTTTAGG

>98660_98660_3_WAC-APBB1IP_WAC_chr10_28872434_ENST00000375646_APBB1IP_chr10_26855890_ENST00000376236_length(amino acids)=296AA_BP=133
MVAKRRSRPQRRRKAGASRAVTTGGGTRSLTRHLSIHRRVTPVAVITDMKRCETPEILHHQIKCCGDLIVLKTNTVTAQVTVRPKMCILT
ELERGMVGPVTLHKKIHTTTVLFIVQIHILLIQAITQAKLQMQIRSQPSGTTTTRQCPGPRTPPSPACPRPLRCGGPPTPAAVPPRPSRP
RAQAAGACPPHPTTSCRRRHRRRPSMTLSSRRRPRTSWSRPQTSCPRPRRRTQGSRAQSCPRRRRRRPRPRPPPSPTPPGRPPRWPRGLL

--------------------------------------------------------------
>98660_98660_4_WAC-APBB1IP_WAC_chr10_28872434_ENST00000375664_APBB1IP_chr10_26855890_ENST00000376236_length(transcript)=1698nt_BP=855nt
GGTGGCGCGCGGCGTCCGGTGAGGGGCAGCGGCCCGGGCTCGGTTCCGGCTTCCAGCAGCGGCCCGAAGGCGCCGGAGCACGCTCCCCGC
TCCCCAGAACGCAGCTTCCGCGGCTGCAGCCCAGGCAGCTCTTCGGGAAGCGTCCGCCCGTGGTCTCGCCAGGGGGTTTCCGACCTCCCC
GCCCGACAGCGCAGGGGCGGGGGCCGCGGCCGGAGAGCTCGCCCGAGAGCACCCCCTCCCGCTGCGCCTCTGGGCGCACGCGCAGCCGCT
GCAGCCTCCCTTATTTAGTCCGCGATGGCTTCCCTCGCGCCCCACCGTCCTCTTCCGGAAGGCGGCTCCCTCCCTGCGCAGCCCGGAGCC
CCTGAGATCAGCCTCGAGCAGGCGCCCGAGCGAGACTATCCCTAAACGGGAACGGCGGTGGCCGACTCGCGAGTGAGGAAAAGAAGGAAA
GGGCAGACTGGTCGCGAAGAGAAGATCCAGGCCTCAGAGGAGGAGAAAGGCCGGAGCCAGCCGAGCTGTCACGACCGGAGGGGGGACTCG
CAGCCTTACCAGGCACTTAAGTATTCATCGAAGAGTCACCCCAGTAGCGGTGATCACAGACATGAAAAGATGCGAGACGCCGGAGATCCT
TCACCACCAAATAAAATGTTGCGGAGATCTGATAGTCCTGAAAACAAATACAGTGACAGCACAGGTCACAGTAAGGCCAAAAATGTGCAT
ACTCACAGAGTTAGAGAGAGGGATGGTGGGACCAGTTACTCTCCACAAGAAAATTCACACAACCACAGTGCTCTTCATAGTTCAAATTCA
CATTCTTCTAATCCAAGCAATAACCCAAGCAAAACTTCAGATGCAGATAAGAAGCCAGCCCTCGGGAACCACCACGACCCGGCAGTGCCC
CGGGCCCCGCACGCCCCCAAGTCCAGCCTGCCCCCGCCCCCTCCGGTGCGGAGGTCCTCCGACACCAGCGGCAGTCCCGCCACGCCCCTC
AAGGCCAAGGGCACAGGCGGCGGGGGCTTGCCCGCCCCACCCGACGACTTCCTGCCGCCGCCGCCACCGCCGCCGCCCCTCGATGACCCT
GAGCTCCCGCCGCCGCCCCCGGACTTCATGGAGCCGCCCCCAGACTTCGTGCCCCCGCCCCCGCCGTCGTACGCAGGGATCGCGGGCTCA
GAGCTGCCCCCGCCGCCGCCGCCGCCGCCCGCGCCCGCGCCCGCCCCCGTCCCCGACTCCGCCAGGCCGCCCCCCGCGGTGGCCAAGAGG
CCTCCTGTGCCCCCCAAGAGGCAAGAGAACCCAGGGCACCCCGGCGGAGCAGGAGGCGGGGAGCAAGATTTCATGTCAGACCTCATGAAA
GCTTTGCAAAAGAAGAGAGGCAACGTGTCCTAGGGACGGGCATGATGAGTGTTCCAGAGGGAGAAGCATCGCTGACCCCGAGCGCAGGTT
TTGCTAGCAGATTGCCCTGACATCTTGTTCATTTCAGATAAAATGTGATGGGAAACTTCTCACTGATGTGCTCAAGTACAGGCATAACCA
TTAACCCAGTAGAGTTCAGAATATCTGCCCAAATGTACATATCGTTCCCATGTATTTTAACCTAAATGGAATGTATCTTCCCTTCCAAGC

>98660_98660_4_WAC-APBB1IP_WAC_chr10_28872434_ENST00000375664_APBB1IP_chr10_26855890_ENST00000376236_length(amino acids)=296AA_BP=133
MVAKRRSRPQRRRKAGASRAVTTGGGTRSLTRHLSIHRRVTPVAVITDMKRCETPEILHHQIKCCGDLIVLKTNTVTAQVTVRPKMCILT
ELERGMVGPVTLHKKIHTTTVLFIVQIHILLIQAITQAKLQMQIRSQPSGTTTTRQCPGPRTPPSPACPRPLRCGGPPTPAAVPPRPSRP
RAQAAGACPPHPTTSCRRRHRRRPSMTLSSRRRPRTSWSRPQTSCPRPRRRTQGSRAQSCPRRRRRRPRPRPPPSPTPPGRPPRWPRGLL

--------------------------------------------------------------
>98660_98660_5_WAC-APBB1IP_WAC_chr10_28872434_ENST00000428935_APBB1IP_chr10_26855890_ENST00000376236_length(transcript)=1309nt_BP=466nt
CCGCCGCCGCCGCCGCCTGCGCGCCCGCCCGCCTTTCGCGGCCGCTCTCCCCCCTCCCCGACACACACTCACAGGCCGGGCATTGATGGT
AATGTATGCGAGGAAACAGCAGAGACTCAGTGATGGCTGTCACGACCGGAGGGGGGACTCGCAGCCTTACCAGGCACTTAAGTATTCATC
GAAGAGTCACCCCAGTAGCGGTGATCACAGACATGAAAAGATGCGAGACGCCGGAGATCCTTCACCACCAAATAAAATGTTGCGGAGATC
TGATAGTCCTGAAAACAAATACAGTGACAGCACAGGTCACAGTAAGGCCAAAAATGTGCATACTCACAGAGTTAGAGAGAGGGATGGTGG
GACCAGTTACTCTCCACAAGAAAATTCACACAACCACAGTGCTCTTCATAGTTCAAATTCACATTCTTCTAATCCAAGCAATAACCCAAG
CAAAACTTCAGATGCAGATAAGAAGCCAGCCCTCGGGAACCACCACGACCCGGCAGTGCCCCGGGCCCCGCACGCCCCCAAGTCCAGCCT
GCCCCCGCCCCCTCCGGTGCGGAGGTCCTCCGACACCAGCGGCAGTCCCGCCACGCCCCTCAAGGCCAAGGGCACAGGCGGCGGGGGCTT
GCCCGCCCCACCCGACGACTTCCTGCCGCCGCCGCCACCGCCGCCGCCCCTCGATGACCCTGAGCTCCCGCCGCCGCCCCCGGACTTCAT
GGAGCCGCCCCCAGACTTCGTGCCCCCGCCCCCGCCGTCGTACGCAGGGATCGCGGGCTCAGAGCTGCCCCCGCCGCCGCCGCCGCCGCC
CGCGCCCGCGCCCGCCCCCGTCCCCGACTCCGCCAGGCCGCCCCCCGCGGTGGCCAAGAGGCCTCCTGTGCCCCCCAAGAGGCAAGAGAA
CCCAGGGCACCCCGGCGGAGCAGGAGGCGGGGAGCAAGATTTCATGTCAGACCTCATGAAAGCTTTGCAAAAGAAGAGAGGCAACGTGTC
CTAGGGACGGGCATGATGAGTGTTCCAGAGGGAGAAGCATCGCTGACCCCGAGCGCAGGTTTTGCTAGCAGATTGCCCTGACATCTTGTT
CATTTCAGATAAAATGTGATGGGAAACTTCTCACTGATGTGCTCAAGTACAGGCATAACCATTAACCCAGTAGAGTTCAGAATATCTGCC
CAAATGTACATATCGTTCCCATGTATTTTAACCTAAATGGAATGTATCTTCCCTTCCAAGCTGCCTAAAGCGCTGTTTTAGGTTCATTTA

>98660_98660_5_WAC-APBB1IP_WAC_chr10_28872434_ENST00000428935_APBB1IP_chr10_26855890_ENST00000376236_length(amino acids)=325AA_BP=150
MRARPPFAAALPPPRHTLTGRALMVMYARKQQRLSDGCHDRRGDSQPYQALKYSSKSHPSSGDHRHEKMRDAGDPSPPNKMLRRSDSPEN
KYSDSTGHSKAKNVHTHRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTSDADKKPALGNHHDPAVPRAPHAPKSSLPPPPP
VRRSSDTSGSPATPLKAKGTGGGGLPAPPDDFLPPPPPPPPLDDPELPPPPPDFMEPPPDFVPPPPPSYAGIAGSELPPPPPPPPAPAPA

--------------------------------------------------------------
>98660_98660_6_WAC-APBB1IP_WAC_chr10_28872436_ENST00000347934_APBB1IP_chr10_26855885_ENST00000376236_length(transcript)=1491nt_BP=648nt
CGTCGTCTTGCCCCCCTCCCCCCGGTTCGCGGTGCCGCCGTGTAGTTGGCGCCGCTGCCCCGGCTGAGAGTGAGCGTGGTGTCGACGGAG
GGAGATGGCCCGGGAGCGCCGGCGCCAGTAACTGGGAGCTGATGAGAGTCGCCGAGGGCGCGCCGGGCCCAGGTGCCGGGGCTGCCCGCC
GCCCGCCGCCGCCGCCGCCTGCGCGCCCGCCCGCCTTTCGCGGCCGCTCTCCCCCCTCCCCGACACACACTCACAGGCCGGGCATTGATG
GTAATGTATGCGAGGAAACAGCAGAGACTCAGTGATGGCTGTCACGACCGGAGGGGGGACTCGCAGCCTTACCAGGCACTTAAGTATTCA
TCGAAGAGTCACCCCAGTAGCGGTGATCACAGACATGAAAAGATGCGAGACGCCGGAGATCCTTCACCACCAAATAAAATGTTGCGGAGA
TCTGATAGTCCTGAAAACAAATACAGTGACAGCACAGGTCACAGTAAGGCCAAAAATGTGCATACTCACAGAGTTAGAGAGAGGGATGGT
GGGACCAGTTACTCTCCACAAGAAAATTCACACAACCACAGTGCTCTTCATAGTTCAAATTCACATTCTTCTAATCCAAGCAATAACCCA
AGCAAAACTTCAGATGCAGATAAGAAGCCAGCCCTCGGGAACCACCACGACCCGGCAGTGCCCCGGGCCCCGCACGCCCCCAAGTCCAGC
CTGCCCCCGCCCCCTCCGGTGCGGAGGTCCTCCGACACCAGCGGCAGTCCCGCCACGCCCCTCAAGGCCAAGGGCACAGGCGGCGGGGGC
TTGCCCGCCCCACCCGACGACTTCCTGCCGCCGCCGCCACCGCCGCCGCCCCTCGATGACCCTGAGCTCCCGCCGCCGCCCCCGGACTTC
ATGGAGCCGCCCCCAGACTTCGTGCCCCCGCCCCCGCCGTCGTACGCAGGGATCGCGGGCTCAGAGCTGCCCCCGCCGCCGCCGCCGCCG
CCCGCGCCCGCGCCCGCCCCCGTCCCCGACTCCGCCAGGCCGCCCCCCGCGGTGGCCAAGAGGCCTCCTGTGCCCCCCAAGAGGCAAGAG
AACCCAGGGCACCCCGGCGGAGCAGGAGGCGGGGAGCAAGATTTCATGTCAGACCTCATGAAAGCTTTGCAAAAGAAGAGAGGCAACGTG
TCCTAGGGACGGGCATGATGAGTGTTCCAGAGGGAGAAGCATCGCTGACCCCGAGCGCAGGTTTTGCTAGCAGATTGCCCTGACATCTTG
TTCATTTCAGATAAAATGTGATGGGAAACTTCTCACTGATGTGCTCAAGTACAGGCATAACCATTAACCCAGTAGAGTTCAGAATATCTG
CCCAAATGTACATATCGTTCCCATGTATTTTAACCTAAATGGAATGTATCTTCCCTTCCAAGCTGCCTAAAGCGCTGTTTTAGGTTCATT

>98660_98660_6_WAC-APBB1IP_WAC_chr10_28872436_ENST00000347934_APBB1IP_chr10_26855885_ENST00000376236_length(amino acids)=334AA_BP=159
MPAARRRRRLRARPPFAAALPPPRHTLTGRALMVMYARKQQRLSDGCHDRRGDSQPYQALKYSSKSHPSSGDHRHEKMRDAGDPSPPNKM
LRRSDSPENKYSDSTGHSKAKNVHTHRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTSDADKKPALGNHHDPAVPRAPHAP
KSSLPPPPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPDDFLPPPPPPPPLDDPELPPPPPDFMEPPPDFVPPPPPSYAGIAGSELPPPP

--------------------------------------------------------------
>98660_98660_7_WAC-APBB1IP_WAC_chr10_28872436_ENST00000354911_APBB1IP_chr10_26855885_ENST00000376236_length(transcript)=1385nt_BP=542nt
CGCCGGCGCCAGTAACTGGGAGCTGATGAGAGTCGCCGAGGGCGCGCCGGGCCCAGGTGCCGGGGCTGCCCGCCGCCCGCCGCCGCCGCC
GCCTGCGCGCCCGCCCGCCTTTCGCGGCCGCTCTCCCCCCTCCCCGACACACACTCACAGGCCGGGCATTGATGGTAATGTATGCGAGGA
AACAGCAGAGACTCAGTGATGGCTGTCACGACCGGAGGGGGGACTCGCAGCCTTACCAGGCACTTAAGTATTCATCGAAGAGTCACCCCA
GTAGCGGTGATCACAGACATGAAAAGATGCGAGACGCCGGAGATCCTTCACCACCAAATAAAATGTTGCGGAGATCTGATAGTCCTGAAA
ACAAATACAGTGACAGCACAGGTCACAGTAAGGCCAAAAATGTGCATACTCACAGAGTTAGAGAGAGGGATGGTGGGACCAGTTACTCTC
CACAAGAAAATTCACACAACCACAGTGCTCTTCATAGTTCAAATTCACATTCTTCTAATCCAAGCAATAACCCAAGCAAAACTTCAGATG
CAGATAAGAAGCCAGCCCTCGGGAACCACCACGACCCGGCAGTGCCCCGGGCCCCGCACGCCCCCAAGTCCAGCCTGCCCCCGCCCCCTC
CGGTGCGGAGGTCCTCCGACACCAGCGGCAGTCCCGCCACGCCCCTCAAGGCCAAGGGCACAGGCGGCGGGGGCTTGCCCGCCCCACCCG
ACGACTTCCTGCCGCCGCCGCCACCGCCGCCGCCCCTCGATGACCCTGAGCTCCCGCCGCCGCCCCCGGACTTCATGGAGCCGCCCCCAG
ACTTCGTGCCCCCGCCCCCGCCGTCGTACGCAGGGATCGCGGGCTCAGAGCTGCCCCCGCCGCCGCCGCCGCCGCCCGCGCCCGCGCCCG
CCCCCGTCCCCGACTCCGCCAGGCCGCCCCCCGCGGTGGCCAAGAGGCCTCCTGTGCCCCCCAAGAGGCAAGAGAACCCAGGGCACCCCG
GCGGAGCAGGAGGCGGGGAGCAAGATTTCATGTCAGACCTCATGAAAGCTTTGCAAAAGAAGAGAGGCAACGTGTCCTAGGGACGGGCAT
GATGAGTGTTCCAGAGGGAGAAGCATCGCTGACCCCGAGCGCAGGTTTTGCTAGCAGATTGCCCTGACATCTTGTTCATTTCAGATAAAA
TGTGATGGGAAACTTCTCACTGATGTGCTCAAGTACAGGCATAACCATTAACCCAGTAGAGTTCAGAATATCTGCCCAAATGTACATATC
GTTCCCATGTATTTTAACCTAAATGGAATGTATCTTCCCTTCCAAGCTGCCTAAAGCGCTGTTTTAGGTTCATTTATTTTATTATGTTCA

>98660_98660_7_WAC-APBB1IP_WAC_chr10_28872436_ENST00000354911_APBB1IP_chr10_26855885_ENST00000376236_length(amino acids)=334AA_BP=159
MPAARRRRRLRARPPFAAALPPPRHTLTGRALMVMYARKQQRLSDGCHDRRGDSQPYQALKYSSKSHPSSGDHRHEKMRDAGDPSPPNKM
LRRSDSPENKYSDSTGHSKAKNVHTHRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTSDADKKPALGNHHDPAVPRAPHAP
KSSLPPPPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPDDFLPPPPPPPPLDDPELPPPPPDFMEPPPDFVPPPPPSYAGIAGSELPPPP

--------------------------------------------------------------
>98660_98660_8_WAC-APBB1IP_WAC_chr10_28872436_ENST00000375646_APBB1IP_chr10_26855885_ENST00000376236_length(transcript)=1407nt_BP=564nt
GCGATGGCTTCCCTCGCGCCCCACCGTCCTCTTCCGGAAGGCGGCTCCCTCCCTGCGCAGCCCGGAGCCCCTGAGATCAGCCTCGAGCAG
GCGCCCGAGCGAGACTATCCCTAAACGGGAACGGCGGTGGCCGACTCGCGAGTGAGGAAAAGAAGGAAAGGGCAGACTGGTCGCGAAGAG
AAGATCCAGGCCTCAGAGGAGGAGAAAGGCCGGAGCCAGCCGAGCTGTCACGACCGGAGGGGGGACTCGCAGCCTTACCAGGCACTTAAG
TATTCATCGAAGAGTCACCCCAGTAGCGGTGATCACAGACATGAAAAGATGCGAGACGCCGGAGATCCTTCACCACCAAATAAAATGTTG
CGGAGATCTGATAGTCCTGAAAACAAATACAGTGACAGCACAGGTCACAGTAAGGCCAAAAATGTGCATACTCACAGAGTTAGAGAGAGG
GATGGTGGGACCAGTTACTCTCCACAAGAAAATTCACACAACCACAGTGCTCTTCATAGTTCAAATTCACATTCTTCTAATCCAAGCAAT
AACCCAAGCAAAACTTCAGATGCAGATAAGAAGCCAGCCCTCGGGAACCACCACGACCCGGCAGTGCCCCGGGCCCCGCACGCCCCCAAG
TCCAGCCTGCCCCCGCCCCCTCCGGTGCGGAGGTCCTCCGACACCAGCGGCAGTCCCGCCACGCCCCTCAAGGCCAAGGGCACAGGCGGC
GGGGGCTTGCCCGCCCCACCCGACGACTTCCTGCCGCCGCCGCCACCGCCGCCGCCCCTCGATGACCCTGAGCTCCCGCCGCCGCCCCCG
GACTTCATGGAGCCGCCCCCAGACTTCGTGCCCCCGCCCCCGCCGTCGTACGCAGGGATCGCGGGCTCAGAGCTGCCCCCGCCGCCGCCG
CCGCCGCCCGCGCCCGCGCCCGCCCCCGTCCCCGACTCCGCCAGGCCGCCCCCCGCGGTGGCCAAGAGGCCTCCTGTGCCCCCCAAGAGG
CAAGAGAACCCAGGGCACCCCGGCGGAGCAGGAGGCGGGGAGCAAGATTTCATGTCAGACCTCATGAAAGCTTTGCAAAAGAAGAGAGGC
AACGTGTCCTAGGGACGGGCATGATGAGTGTTCCAGAGGGAGAAGCATCGCTGACCCCGAGCGCAGGTTTTGCTAGCAGATTGCCCTGAC
ATCTTGTTCATTTCAGATAAAATGTGATGGGAAACTTCTCACTGATGTGCTCAAGTACAGGCATAACCATTAACCCAGTAGAGTTCAGAA
TATCTGCCCAAATGTACATATCGTTCCCATGTATTTTAACCTAAATGGAATGTATCTTCCCTTCCAAGCTGCCTAAAGCGCTGTTTTAGG

>98660_98660_8_WAC-APBB1IP_WAC_chr10_28872436_ENST00000375646_APBB1IP_chr10_26855885_ENST00000376236_length(amino acids)=296AA_BP=133
MVAKRRSRPQRRRKAGASRAVTTGGGTRSLTRHLSIHRRVTPVAVITDMKRCETPEILHHQIKCCGDLIVLKTNTVTAQVTVRPKMCILT
ELERGMVGPVTLHKKIHTTTVLFIVQIHILLIQAITQAKLQMQIRSQPSGTTTTRQCPGPRTPPSPACPRPLRCGGPPTPAAVPPRPSRP
RAQAAGACPPHPTTSCRRRHRRRPSMTLSSRRRPRTSWSRPQTSCPRPRRRTQGSRAQSCPRRRRRRPRPRPPPSPTPPGRPPRWPRGLL

--------------------------------------------------------------
>98660_98660_9_WAC-APBB1IP_WAC_chr10_28872436_ENST00000375664_APBB1IP_chr10_26855885_ENST00000376236_length(transcript)=1698nt_BP=855nt
GGTGGCGCGCGGCGTCCGGTGAGGGGCAGCGGCCCGGGCTCGGTTCCGGCTTCCAGCAGCGGCCCGAAGGCGCCGGAGCACGCTCCCCGC
TCCCCAGAACGCAGCTTCCGCGGCTGCAGCCCAGGCAGCTCTTCGGGAAGCGTCCGCCCGTGGTCTCGCCAGGGGGTTTCCGACCTCCCC
GCCCGACAGCGCAGGGGCGGGGGCCGCGGCCGGAGAGCTCGCCCGAGAGCACCCCCTCCCGCTGCGCCTCTGGGCGCACGCGCAGCCGCT
GCAGCCTCCCTTATTTAGTCCGCGATGGCTTCCCTCGCGCCCCACCGTCCTCTTCCGGAAGGCGGCTCCCTCCCTGCGCAGCCCGGAGCC
CCTGAGATCAGCCTCGAGCAGGCGCCCGAGCGAGACTATCCCTAAACGGGAACGGCGGTGGCCGACTCGCGAGTGAGGAAAAGAAGGAAA
GGGCAGACTGGTCGCGAAGAGAAGATCCAGGCCTCAGAGGAGGAGAAAGGCCGGAGCCAGCCGAGCTGTCACGACCGGAGGGGGGACTCG
CAGCCTTACCAGGCACTTAAGTATTCATCGAAGAGTCACCCCAGTAGCGGTGATCACAGACATGAAAAGATGCGAGACGCCGGAGATCCT
TCACCACCAAATAAAATGTTGCGGAGATCTGATAGTCCTGAAAACAAATACAGTGACAGCACAGGTCACAGTAAGGCCAAAAATGTGCAT
ACTCACAGAGTTAGAGAGAGGGATGGTGGGACCAGTTACTCTCCACAAGAAAATTCACACAACCACAGTGCTCTTCATAGTTCAAATTCA
CATTCTTCTAATCCAAGCAATAACCCAAGCAAAACTTCAGATGCAGATAAGAAGCCAGCCCTCGGGAACCACCACGACCCGGCAGTGCCC
CGGGCCCCGCACGCCCCCAAGTCCAGCCTGCCCCCGCCCCCTCCGGTGCGGAGGTCCTCCGACACCAGCGGCAGTCCCGCCACGCCCCTC
AAGGCCAAGGGCACAGGCGGCGGGGGCTTGCCCGCCCCACCCGACGACTTCCTGCCGCCGCCGCCACCGCCGCCGCCCCTCGATGACCCT
GAGCTCCCGCCGCCGCCCCCGGACTTCATGGAGCCGCCCCCAGACTTCGTGCCCCCGCCCCCGCCGTCGTACGCAGGGATCGCGGGCTCA
GAGCTGCCCCCGCCGCCGCCGCCGCCGCCCGCGCCCGCGCCCGCCCCCGTCCCCGACTCCGCCAGGCCGCCCCCCGCGGTGGCCAAGAGG
CCTCCTGTGCCCCCCAAGAGGCAAGAGAACCCAGGGCACCCCGGCGGAGCAGGAGGCGGGGAGCAAGATTTCATGTCAGACCTCATGAAA
GCTTTGCAAAAGAAGAGAGGCAACGTGTCCTAGGGACGGGCATGATGAGTGTTCCAGAGGGAGAAGCATCGCTGACCCCGAGCGCAGGTT
TTGCTAGCAGATTGCCCTGACATCTTGTTCATTTCAGATAAAATGTGATGGGAAACTTCTCACTGATGTGCTCAAGTACAGGCATAACCA
TTAACCCAGTAGAGTTCAGAATATCTGCCCAAATGTACATATCGTTCCCATGTATTTTAACCTAAATGGAATGTATCTTCCCTTCCAAGC

>98660_98660_9_WAC-APBB1IP_WAC_chr10_28872436_ENST00000375664_APBB1IP_chr10_26855885_ENST00000376236_length(amino acids)=296AA_BP=133
MVAKRRSRPQRRRKAGASRAVTTGGGTRSLTRHLSIHRRVTPVAVITDMKRCETPEILHHQIKCCGDLIVLKTNTVTAQVTVRPKMCILT
ELERGMVGPVTLHKKIHTTTVLFIVQIHILLIQAITQAKLQMQIRSQPSGTTTTRQCPGPRTPPSPACPRPLRCGGPPTPAAVPPRPSRP
RAQAAGACPPHPTTSCRRRHRRRPSMTLSSRRRPRTSWSRPQTSCPRPRRRTQGSRAQSCPRRRRRRPRPRPPPSPTPPGRPPRWPRGLL

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>98660_98660_10_WAC-APBB1IP_WAC_chr10_28872436_ENST00000428935_APBB1IP_chr10_26855885_ENST00000376236_length(transcript)=1309nt_BP=466nt
CCGCCGCCGCCGCCGCCTGCGCGCCCGCCCGCCTTTCGCGGCCGCTCTCCCCCCTCCCCGACACACACTCACAGGCCGGGCATTGATGGT
AATGTATGCGAGGAAACAGCAGAGACTCAGTGATGGCTGTCACGACCGGAGGGGGGACTCGCAGCCTTACCAGGCACTTAAGTATTCATC
GAAGAGTCACCCCAGTAGCGGTGATCACAGACATGAAAAGATGCGAGACGCCGGAGATCCTTCACCACCAAATAAAATGTTGCGGAGATC
TGATAGTCCTGAAAACAAATACAGTGACAGCACAGGTCACAGTAAGGCCAAAAATGTGCATACTCACAGAGTTAGAGAGAGGGATGGTGG
GACCAGTTACTCTCCACAAGAAAATTCACACAACCACAGTGCTCTTCATAGTTCAAATTCACATTCTTCTAATCCAAGCAATAACCCAAG
CAAAACTTCAGATGCAGATAAGAAGCCAGCCCTCGGGAACCACCACGACCCGGCAGTGCCCCGGGCCCCGCACGCCCCCAAGTCCAGCCT
GCCCCCGCCCCCTCCGGTGCGGAGGTCCTCCGACACCAGCGGCAGTCCCGCCACGCCCCTCAAGGCCAAGGGCACAGGCGGCGGGGGCTT
GCCCGCCCCACCCGACGACTTCCTGCCGCCGCCGCCACCGCCGCCGCCCCTCGATGACCCTGAGCTCCCGCCGCCGCCCCCGGACTTCAT
GGAGCCGCCCCCAGACTTCGTGCCCCCGCCCCCGCCGTCGTACGCAGGGATCGCGGGCTCAGAGCTGCCCCCGCCGCCGCCGCCGCCGCC
CGCGCCCGCGCCCGCCCCCGTCCCCGACTCCGCCAGGCCGCCCCCCGCGGTGGCCAAGAGGCCTCCTGTGCCCCCCAAGAGGCAAGAGAA
CCCAGGGCACCCCGGCGGAGCAGGAGGCGGGGAGCAAGATTTCATGTCAGACCTCATGAAAGCTTTGCAAAAGAAGAGAGGCAACGTGTC
CTAGGGACGGGCATGATGAGTGTTCCAGAGGGAGAAGCATCGCTGACCCCGAGCGCAGGTTTTGCTAGCAGATTGCCCTGACATCTTGTT
CATTTCAGATAAAATGTGATGGGAAACTTCTCACTGATGTGCTCAAGTACAGGCATAACCATTAACCCAGTAGAGTTCAGAATATCTGCC
CAAATGTACATATCGTTCCCATGTATTTTAACCTAAATGGAATGTATCTTCCCTTCCAAGCTGCCTAAAGCGCTGTTTTAGGTTCATTTA

>98660_98660_10_WAC-APBB1IP_WAC_chr10_28872436_ENST00000428935_APBB1IP_chr10_26855885_ENST00000376236_length(amino acids)=325AA_BP=150
MRARPPFAAALPPPRHTLTGRALMVMYARKQQRLSDGCHDRRGDSQPYQALKYSSKSHPSSGDHRHEKMRDAGDPSPPNKMLRRSDSPEN
KYSDSTGHSKAKNVHTHRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTSDADKKPALGNHHDPAVPRAPHAPKSSLPPPPP
VRRSSDTSGSPATPLKAKGTGGGGLPAPPDDFLPPPPPPPPLDDPELPPPPPDFMEPPPDFVPPPPPSYAGIAGSELPPPPPPPPAPAPA

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Fusion Gene PPI Analysis for WAC-APBB1IP


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for WAC-APBB1IP


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for WAC-APBB1IP


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource