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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:WDFY1-AP1S3 (FusionGDB2 ID:98821)

Fusion Gene Summary for WDFY1-AP1S3

check button Fusion gene summary
Fusion gene informationFusion gene name: WDFY1-AP1S3
Fusion gene ID: 98821
HgeneTgene
Gene symbol

WDFY1

AP1S3

Gene ID

57590

130340

Gene nameWD repeat and FYVE domain containing 1adaptor related protein complex 1 subunit sigma 3
SynonymsFENS-1|FENS1|WDF1|ZFYVE17PSORS15
Cytomap

2q36.1

2q36.1

Type of geneprotein-codingprotein-coding
DescriptionWD repeat and FYVE domain-containing protein 1FYVE domain-containing protein localized to endosomes 1WD40- and FYVE domain-containing protein 1phosphoinositide-binding protein SR1zinc finger FYVE domain-containing protein 17AP-1 complex subunit sigma-3adapter-related protein complex 1 subunit sigma-1Cadaptor protein complex AP-1 sigma-1C subunitadaptor related protein complex 1 sigma 3 subunitadaptor-related protein complex 1 subunit sigma-1Cclathrin assembly protein co
Modification date2020031320200313
UniProtAcc.

Q96PC3

Ensembl transtripts involved in fusion geneENST00000233055, ENST00000462702, 
ENST00000396653, ENST00000396654, 
ENST00000409375, ENST00000423110, 
ENST00000443700, ENST00000446015, 
Fusion gene scores* DoF score4 X 4 X 3=484 X 2 X 3=24
# samples 65
** MAII scorelog2(6/48*10)=0.321928094887362
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(5/24*10)=1.05889368905357
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: WDFY1 [Title/Abstract] AND AP1S3 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointAP1S3(224632653)-WDFY1(224730175), # samples:1
WDFY1(224809865)-AP1S3(224642586), # samples:1
WDFY1(224749365)-AP1S3(224642586), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across WDFY1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across AP1S3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-CD-8534-01AWDFY1chr2

224749365

-AP1S3chr2

224642586

-
ChimerDB4STADTCGA-HJ-7597-01AWDFY1chr2

224809865

-AP1S3chr2

224642586

-


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Fusion Gene ORF analysis for WDFY1-AP1S3

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000233055ENST00000396653WDFY1chr2

224749365

-AP1S3chr2

224642586

-
In-frameENST00000233055ENST00000396653WDFY1chr2

224809865

-AP1S3chr2

224642586

-
In-frameENST00000233055ENST00000396654WDFY1chr2

224749365

-AP1S3chr2

224642586

-
In-frameENST00000233055ENST00000396654WDFY1chr2

224809865

-AP1S3chr2

224642586

-
In-frameENST00000233055ENST00000409375WDFY1chr2

224749365

-AP1S3chr2

224642586

-
In-frameENST00000233055ENST00000409375WDFY1chr2

224809865

-AP1S3chr2

224642586

-
In-frameENST00000233055ENST00000423110WDFY1chr2

224749365

-AP1S3chr2

224642586

-
In-frameENST00000233055ENST00000423110WDFY1chr2

224809865

-AP1S3chr2

224642586

-
In-frameENST00000233055ENST00000443700WDFY1chr2

224749365

-AP1S3chr2

224642586

-
In-frameENST00000233055ENST00000443700WDFY1chr2

224809865

-AP1S3chr2

224642586

-
In-frameENST00000233055ENST00000446015WDFY1chr2

224749365

-AP1S3chr2

224642586

-
In-frameENST00000233055ENST00000446015WDFY1chr2

224809865

-AP1S3chr2

224642586

-
intron-3CDSENST00000462702ENST00000396653WDFY1chr2

224749365

-AP1S3chr2

224642586

-
intron-3CDSENST00000462702ENST00000396653WDFY1chr2

224809865

-AP1S3chr2

224642586

-
intron-3CDSENST00000462702ENST00000396654WDFY1chr2

224749365

-AP1S3chr2

224642586

-
intron-3CDSENST00000462702ENST00000396654WDFY1chr2

224809865

-AP1S3chr2

224642586

-
intron-3CDSENST00000462702ENST00000409375WDFY1chr2

224749365

-AP1S3chr2

224642586

-
intron-3CDSENST00000462702ENST00000409375WDFY1chr2

224809865

-AP1S3chr2

224642586

-
intron-3CDSENST00000462702ENST00000423110WDFY1chr2

224749365

-AP1S3chr2

224642586

-
intron-3CDSENST00000462702ENST00000423110WDFY1chr2

224809865

-AP1S3chr2

224642586

-
intron-3CDSENST00000462702ENST00000443700WDFY1chr2

224749365

-AP1S3chr2

224642586

-
intron-3CDSENST00000462702ENST00000443700WDFY1chr2

224809865

-AP1S3chr2

224642586

-
intron-3CDSENST00000462702ENST00000446015WDFY1chr2

224749365

-AP1S3chr2

224642586

-
intron-3CDSENST00000462702ENST00000446015WDFY1chr2

224809865

-AP1S3chr2

224642586

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000233055WDFY1chr2224809865-ENST00000443700AP1S3chr2224642586-187024057731224
ENST00000233055WDFY1chr2224809865-ENST00000396654AP1S3chr2224642586-93524057701214
ENST00000233055WDFY1chr2224809865-ENST00000396653AP1S3chr2224642586-69424057428123
ENST00000233055WDFY1chr2224809865-ENST00000446015AP1S3chr2224642586-70224057701214
ENST00000233055WDFY1chr2224809865-ENST00000409375AP1S3chr2224642586-69824057650197
ENST00000233055WDFY1chr2224809865-ENST00000423110AP1S3chr2224642586-55224057551164
ENST00000233055WDFY1chr2224749365-ENST00000443700AP1S3chr2224642586-266610361031527474
ENST00000233055WDFY1chr2224749365-ENST00000396654AP1S3chr2224642586-173110361031497464
ENST00000233055WDFY1chr2224749365-ENST00000396653AP1S3chr2224642586-149010361031224373
ENST00000233055WDFY1chr2224749365-ENST00000446015AP1S3chr2224642586-149810361031497465
ENST00000233055WDFY1chr2224749365-ENST00000409375AP1S3chr2224642586-149410361031446447
ENST00000233055WDFY1chr2224749365-ENST00000423110AP1S3chr2224642586-134810361031347415

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000233055ENST00000443700WDFY1chr2224809865-AP1S3chr2224642586-0.0026309620.99736905
ENST00000233055ENST00000396654WDFY1chr2224809865-AP1S3chr2224642586-0.0011611310.99883884
ENST00000233055ENST00000396653WDFY1chr2224809865-AP1S3chr2224642586-0.33308970.66691023
ENST00000233055ENST00000446015WDFY1chr2224809865-AP1S3chr2224642586-0.005061660.9949384
ENST00000233055ENST00000409375WDFY1chr2224809865-AP1S3chr2224642586-0.0339767560.96602327
ENST00000233055ENST00000423110WDFY1chr2224809865-AP1S3chr2224642586-0.0395237360.96047634
ENST00000233055ENST00000443700WDFY1chr2224749365-AP1S3chr2224642586-0.0021467070.9978532
ENST00000233055ENST00000396654WDFY1chr2224749365-AP1S3chr2224642586-0.0032739210.99672604
ENST00000233055ENST00000396653WDFY1chr2224749365-AP1S3chr2224642586-0.0229692240.97703075
ENST00000233055ENST00000446015WDFY1chr2224749365-AP1S3chr2224642586-0.0108262750.98917377
ENST00000233055ENST00000409375WDFY1chr2224749365-AP1S3chr2224642586-0.032512590.9674874
ENST00000233055ENST00000423110WDFY1chr2224749365-AP1S3chr2224642586-0.037325550.9626744

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Fusion Genomic Features for WDFY1-AP1S3


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for WDFY1-AP1S3


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:224632653/chr2:224730175)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.AP1S3

Q96PC3

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. Involved in TLR3 trafficking (PubMed:24791904). {ECO:0000269|PubMed:24791904}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneWDFY1chr2:224749365chr2:224642586ENST00000233055-912112_150311411.0RepeatNote=WD 3
HgeneWDFY1chr2:224749365chr2:224642586ENST00000233055-912153_192311411.0RepeatNote=WD 4
HgeneWDFY1chr2:224749365chr2:224642586ENST00000233055-912197_236311411.0RepeatNote=WD 5
HgeneWDFY1chr2:224749365chr2:224642586ENST00000233055-91222_61311411.0RepeatNote=WD 1
HgeneWDFY1chr2:224749365chr2:224642586ENST00000233055-912240_279311411.0RepeatNote=WD 6
HgeneWDFY1chr2:224749365chr2:224642586ENST00000233055-91266_105311411.0RepeatNote=WD 2

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneWDFY1chr2:224749365chr2:224642586ENST00000233055-912364_403311411.0RepeatNote=WD 7
HgeneWDFY1chr2:224809865chr2:224642586ENST00000233055-112112_15045411.0RepeatNote=WD 3
HgeneWDFY1chr2:224809865chr2:224642586ENST00000233055-112153_19245411.0RepeatNote=WD 4
HgeneWDFY1chr2:224809865chr2:224642586ENST00000233055-112197_23645411.0RepeatNote=WD 5
HgeneWDFY1chr2:224809865chr2:224642586ENST00000233055-11222_6145411.0RepeatNote=WD 1
HgeneWDFY1chr2:224809865chr2:224642586ENST00000233055-112240_27945411.0RepeatNote=WD 6
HgeneWDFY1chr2:224809865chr2:224642586ENST00000233055-112364_40345411.0RepeatNote=WD 7
HgeneWDFY1chr2:224809865chr2:224642586ENST00000233055-11266_10545411.0RepeatNote=WD 2
HgeneWDFY1chr2:224749365chr2:224642586ENST00000233055-912281_352311411.0Zinc fingerFYVE-type
HgeneWDFY1chr2:224809865chr2:224642586ENST00000233055-112281_35245411.0Zinc fingerFYVE-type


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Fusion Gene Sequence for WDFY1-AP1S3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>98821_98821_1_WDFY1-AP1S3_WDFY1_chr2_224749365_ENST00000233055_AP1S3_chr2_224642586_ENST00000396653_length(transcript)=1490nt_BP=1036nt
AAGAGGCCCCAGCAGCCGAAGGGAAACCGGCGCGTCCCCCGCCCGCCCAGGCGTCAGCTGATGGGCTGCCTGCCGAGGAGGCCGCAGCAG
TCGCCGCGCGAACATGGCGGCCGAAATCCACTCCAGGCCGCAGAGCAGCCGCCCGGTGCTGCTGAGCAAGATCGAGGGGCACCAGGACGC
CGTCACGGCCGCGCTGCTCATCCCCAAGGAGGACGGCGTGATCACGGCCAGCGAGGACAGAACCATCCGGGTATGGCTGAAAAGAGACAG
TGGTCAATACTGGCCCAGCATTTACCACACAATGGCCTCTCCTTGCTCTGCTATGGCTTACCATCATGACAGCAGACGGATATTTGTGGG
CCAGGATAATGGAGCTGTAATGGAATTTCACGTTTCTGAAGATTTTAATAAAATGAACTTTATCAAGACCTACCCAGCTCATCAGAACCG
GGTGTCTGCGATTATCTTCAGCTTGGCCACAGAGTGGGTGATCAGTACCGGCCACGACAAGTGTGTGAGCTGGATGTGCACGCGGAGCGG
GAACATGCTCGGGAGGCACTTCTTCACGTCCTGGGCTTCGTGTCTGCAATATGACTTTGACACTCAGTATGCTTTCGTTGGTGATTATTC
TGGGCAGATCACCCTGCTGAAGCTTGAACAGAACACGTGTTCAGTCATCACAACCCTCAAAGGACATGAAGGTAGTGTCGCCTGCCTCTG
GTGGGACCCTATTCAGCGGTTACTCTTCTCAGGAGCATCTGACAACAGCATCATCATGTGGGACATCGGAGGAAGGAAAGGCCGGACGCT
GTTACTTCAGGGCCATCATGACAAGGTGCAGTCGCTGTGCTACCTTCAGCTCACCAGGCAGCTCGTCTCCTGTTCCTCGGACGGCGGAAT
TGCAGTGTGGAACATGGATGTTAGCAGAGAAGAGGCTCCTCAGTGGTTGGAAAGTGATTCTTGTCAGAAATGTGAGCAGCCATTTTTCTG
GAACATAAAGCAGATGTGGGACACCAAGACGCTGGGGCTAAGACAAATACATTTCATATTGCTCTTCAGTCGACAAGGGAAATTACGGCT
ACAGAAATGGTACATCACTCTCCCTGATAAAGAGAGGAAGAAGATCACCCGGGAAATTGTTCAGATTATTCTCTCCCGTGGTCACAGGAC
AAGCAGTTTTGTTGACTGGAAGGAGCTAAAACTTGTTTATAAAAGGTGTCTGTGAGCTGGATATTATCTTTAATTTTGAAAAGGCTTATT
TCATCCTGGACGAGTTTATAATAGGTGGGGAAATTCAGGAAACATCCAAGAAAATTGCTGTCAAAGCCATTGAAGACTCTGATATGTTAC
AGGAGGTCAGTACGGTTTCCCAAACCATGGGAGAAAGATGATGATGATGATGATGATGGTGTTAATAATTATAATATTAACCAGACTTAC

>98821_98821_1_WDFY1-AP1S3_WDFY1_chr2_224749365_ENST00000233055_AP1S3_chr2_224642586_ENST00000396653_length(amino acids)=373AA_BP=0
MAAEIHSRPQSSRPVLLSKIEGHQDAVTAALLIPKEDGVITASEDRTIRVWLKRDSGQYWPSIYHTMASPCSAMAYHHDSRRIFVGQDNG
AVMEFHVSEDFNKMNFIKTYPAHQNRVSAIIFSLATEWVISTGHDKCVSWMCTRSGNMLGRHFFTSWASCLQYDFDTQYAFVGDYSGQIT
LLKLEQNTCSVITTLKGHEGSVACLWWDPIQRLLFSGASDNSIIMWDIGGRKGRTLLLQGHHDKVQSLCYLQLTRQLVSCSSDGGIAVWN
MDVSREEAPQWLESDSCQKCEQPFFWNIKQMWDTKTLGLRQIHFILLFSRQGKLRLQKWYITLPDKERKKITREIVQIILSRGHRTSSFV

--------------------------------------------------------------
>98821_98821_2_WDFY1-AP1S3_WDFY1_chr2_224749365_ENST00000233055_AP1S3_chr2_224642586_ENST00000396654_length(transcript)=1731nt_BP=1036nt
AAGAGGCCCCAGCAGCCGAAGGGAAACCGGCGCGTCCCCCGCCCGCCCAGGCGTCAGCTGATGGGCTGCCTGCCGAGGAGGCCGCAGCAG
TCGCCGCGCGAACATGGCGGCCGAAATCCACTCCAGGCCGCAGAGCAGCCGCCCGGTGCTGCTGAGCAAGATCGAGGGGCACCAGGACGC
CGTCACGGCCGCGCTGCTCATCCCCAAGGAGGACGGCGTGATCACGGCCAGCGAGGACAGAACCATCCGGGTATGGCTGAAAAGAGACAG
TGGTCAATACTGGCCCAGCATTTACCACACAATGGCCTCTCCTTGCTCTGCTATGGCTTACCATCATGACAGCAGACGGATATTTGTGGG
CCAGGATAATGGAGCTGTAATGGAATTTCACGTTTCTGAAGATTTTAATAAAATGAACTTTATCAAGACCTACCCAGCTCATCAGAACCG
GGTGTCTGCGATTATCTTCAGCTTGGCCACAGAGTGGGTGATCAGTACCGGCCACGACAAGTGTGTGAGCTGGATGTGCACGCGGAGCGG
GAACATGCTCGGGAGGCACTTCTTCACGTCCTGGGCTTCGTGTCTGCAATATGACTTTGACACTCAGTATGCTTTCGTTGGTGATTATTC
TGGGCAGATCACCCTGCTGAAGCTTGAACAGAACACGTGTTCAGTCATCACAACCCTCAAAGGACATGAAGGTAGTGTCGCCTGCCTCTG
GTGGGACCCTATTCAGCGGTTACTCTTCTCAGGAGCATCTGACAACAGCATCATCATGTGGGACATCGGAGGAAGGAAAGGCCGGACGCT
GTTACTTCAGGGCCATCATGACAAGGTGCAGTCGCTGTGCTACCTTCAGCTCACCAGGCAGCTCGTCTCCTGTTCCTCGGACGGCGGAAT
TGCAGTGTGGAACATGGATGTTAGCAGAGAAGAGGCTCCTCAGTGGTTGGAAAGTGATTCTTGTCAGAAATGTGAGCAGCCATTTTTCTG
GAACATAAAGCAGATGTGGGACACCAAGACGCTGGGGCTAAGACAAATACATTTCATATTGCTCTTCAGTCGACAAGGGAAATTACGGCT
ACAGAAATGGTACATCACTCTCCCTGATAAAGAGAGGAAGAAGATCACCCGGGAAATTGTTCAGATTATTCTCTCCCGTGGTCACAGGAC
AAGCAGTTTTGTTGACTGGAAGGAGCTAAAACTTGTTTATAAAAGGTATGCTAGTTTATATTTTTGCTGTGCAATAGAAAATCAGGACAA
TGAGCTCTTGACGCTAGAGATTGTGCATCGTTACGTGGAGCTGCTGGACAAATATTTTGGAAATGTCTGTGAGCTGGATATTATCTTTAA
TTTTGAAAAGGCTTATTTCATCCTGGACGAGTTTATAATAGGTGGGGAAATTCAGGAAACATCCAAGAAAATTGCTGTCAAAGCCATTGA
AGACTCTGATATGTTACAGGAGACAATGGAAGAATACATGAACAAGCCTACATTTTAACTGGAAATCTACTTGAAGACTCCAGCACTACA
TGTTATGAAGCTGTAAATAAGCAACGCCTCCCATCCGGTTTTTTGATGGAGCCTCAGGCACCATGCCAAAAATAATTTAAAGGGATTCTT
TGTTAACTAACAAAGTTAAAGTTGTTTAACATATTTATAATTACTATGTGTCTGTATTATTAAAAAAAATTATGTGTCTGTGTTATACTG

>98821_98821_2_WDFY1-AP1S3_WDFY1_chr2_224749365_ENST00000233055_AP1S3_chr2_224642586_ENST00000396654_length(amino acids)=464AA_BP=0
MAAEIHSRPQSSRPVLLSKIEGHQDAVTAALLIPKEDGVITASEDRTIRVWLKRDSGQYWPSIYHTMASPCSAMAYHHDSRRIFVGQDNG
AVMEFHVSEDFNKMNFIKTYPAHQNRVSAIIFSLATEWVISTGHDKCVSWMCTRSGNMLGRHFFTSWASCLQYDFDTQYAFVGDYSGQIT
LLKLEQNTCSVITTLKGHEGSVACLWWDPIQRLLFSGASDNSIIMWDIGGRKGRTLLLQGHHDKVQSLCYLQLTRQLVSCSSDGGIAVWN
MDVSREEAPQWLESDSCQKCEQPFFWNIKQMWDTKTLGLRQIHFILLFSRQGKLRLQKWYITLPDKERKKITREIVQIILSRGHRTSSFV
DWKELKLVYKRYASLYFCCAIENQDNELLTLEIVHRYVELLDKYFGNVCELDIIFNFEKAYFILDEFIIGGEIQETSKKIAVKAIEDSDM

--------------------------------------------------------------
>98821_98821_3_WDFY1-AP1S3_WDFY1_chr2_224749365_ENST00000233055_AP1S3_chr2_224642586_ENST00000409375_length(transcript)=1494nt_BP=1036nt
AAGAGGCCCCAGCAGCCGAAGGGAAACCGGCGCGTCCCCCGCCCGCCCAGGCGTCAGCTGATGGGCTGCCTGCCGAGGAGGCCGCAGCAG
TCGCCGCGCGAACATGGCGGCCGAAATCCACTCCAGGCCGCAGAGCAGCCGCCCGGTGCTGCTGAGCAAGATCGAGGGGCACCAGGACGC
CGTCACGGCCGCGCTGCTCATCCCCAAGGAGGACGGCGTGATCACGGCCAGCGAGGACAGAACCATCCGGGTATGGCTGAAAAGAGACAG
TGGTCAATACTGGCCCAGCATTTACCACACAATGGCCTCTCCTTGCTCTGCTATGGCTTACCATCATGACAGCAGACGGATATTTGTGGG
CCAGGATAATGGAGCTGTAATGGAATTTCACGTTTCTGAAGATTTTAATAAAATGAACTTTATCAAGACCTACCCAGCTCATCAGAACCG
GGTGTCTGCGATTATCTTCAGCTTGGCCACAGAGTGGGTGATCAGTACCGGCCACGACAAGTGTGTGAGCTGGATGTGCACGCGGAGCGG
GAACATGCTCGGGAGGCACTTCTTCACGTCCTGGGCTTCGTGTCTGCAATATGACTTTGACACTCAGTATGCTTTCGTTGGTGATTATTC
TGGGCAGATCACCCTGCTGAAGCTTGAACAGAACACGTGTTCAGTCATCACAACCCTCAAAGGACATGAAGGTAGTGTCGCCTGCCTCTG
GTGGGACCCTATTCAGCGGTTACTCTTCTCAGGAGCATCTGACAACAGCATCATCATGTGGGACATCGGAGGAAGGAAAGGCCGGACGCT
GTTACTTCAGGGCCATCATGACAAGGTGCAGTCGCTGTGCTACCTTCAGCTCACCAGGCAGCTCGTCTCCTGTTCCTCGGACGGCGGAAT
TGCAGTGTGGAACATGGATGTTAGCAGAGAAGAGGCTCCTCAGTGGTTGGAAAGTGATTCTTGTCAGAAATGTGAGCAGCCATTTTTCTG
GAACATAAAGCAGATGTGGGACACCAAGACGCTGGGGCTAAGACAAATACATTTCATATTGCTCTTCAGTCGACAAGGGAAATTACGGCT
ACAGAAATGGTACATCACTCTCCCTGATAAAGAGAGGAAGAAGATCACCCGGGAAATTGTTCAGATTATTCTCTCCCGTGGTCACAGGAC
AAGCAGTTTTGTTGACTGGAAGGAGCTAAAACTTGTTTATAAAAGGTATGCTAGTTTATATTTTTGCTGTGCAATAGAAAATCAGGACAA
TGAGCTCTTGACGCTAGAGATTGTGCATCGTTACGTGGAGCTGCTGGACAAATATTTTGGAAATGAGTTTAATTGCTGGTTTCTCCTAAT
GAGGCTCCTGTCTGTCTTGGATTCCTGGTCTACGCCTGCCTTGAACTCCGAGGTTCCTCAGCTTGCTACTATAACTCCTGACTTCTGCCT

>98821_98821_3_WDFY1-AP1S3_WDFY1_chr2_224749365_ENST00000233055_AP1S3_chr2_224642586_ENST00000409375_length(amino acids)=447AA_BP=0
MAAEIHSRPQSSRPVLLSKIEGHQDAVTAALLIPKEDGVITASEDRTIRVWLKRDSGQYWPSIYHTMASPCSAMAYHHDSRRIFVGQDNG
AVMEFHVSEDFNKMNFIKTYPAHQNRVSAIIFSLATEWVISTGHDKCVSWMCTRSGNMLGRHFFTSWASCLQYDFDTQYAFVGDYSGQIT
LLKLEQNTCSVITTLKGHEGSVACLWWDPIQRLLFSGASDNSIIMWDIGGRKGRTLLLQGHHDKVQSLCYLQLTRQLVSCSSDGGIAVWN
MDVSREEAPQWLESDSCQKCEQPFFWNIKQMWDTKTLGLRQIHFILLFSRQGKLRLQKWYITLPDKERKKITREIVQIILSRGHRTSSFV

--------------------------------------------------------------
>98821_98821_4_WDFY1-AP1S3_WDFY1_chr2_224749365_ENST00000233055_AP1S3_chr2_224642586_ENST00000423110_length(transcript)=1348nt_BP=1036nt
AAGAGGCCCCAGCAGCCGAAGGGAAACCGGCGCGTCCCCCGCCCGCCCAGGCGTCAGCTGATGGGCTGCCTGCCGAGGAGGCCGCAGCAG
TCGCCGCGCGAACATGGCGGCCGAAATCCACTCCAGGCCGCAGAGCAGCCGCCCGGTGCTGCTGAGCAAGATCGAGGGGCACCAGGACGC
CGTCACGGCCGCGCTGCTCATCCCCAAGGAGGACGGCGTGATCACGGCCAGCGAGGACAGAACCATCCGGGTATGGCTGAAAAGAGACAG
TGGTCAATACTGGCCCAGCATTTACCACACAATGGCCTCTCCTTGCTCTGCTATGGCTTACCATCATGACAGCAGACGGATATTTGTGGG
CCAGGATAATGGAGCTGTAATGGAATTTCACGTTTCTGAAGATTTTAATAAAATGAACTTTATCAAGACCTACCCAGCTCATCAGAACCG
GGTGTCTGCGATTATCTTCAGCTTGGCCACAGAGTGGGTGATCAGTACCGGCCACGACAAGTGTGTGAGCTGGATGTGCACGCGGAGCGG
GAACATGCTCGGGAGGCACTTCTTCACGTCCTGGGCTTCGTGTCTGCAATATGACTTTGACACTCAGTATGCTTTCGTTGGTGATTATTC
TGGGCAGATCACCCTGCTGAAGCTTGAACAGAACACGTGTTCAGTCATCACAACCCTCAAAGGACATGAAGGTAGTGTCGCCTGCCTCTG
GTGGGACCCTATTCAGCGGTTACTCTTCTCAGGAGCATCTGACAACAGCATCATCATGTGGGACATCGGAGGAAGGAAAGGCCGGACGCT
GTTACTTCAGGGCCATCATGACAAGGTGCAGTCGCTGTGCTACCTTCAGCTCACCAGGCAGCTCGTCTCCTGTTCCTCGGACGGCGGAAT
TGCAGTGTGGAACATGGATGTTAGCAGAGAAGAGGCTCCTCAGTGGTTGGAAAGTGATTCTTGTCAGAAATGTGAGCAGCCATTTTTCTG
GAACATAAAGCAGATGTGGGACACCAAGACGCTGGGGCTAAGACAAATACATTTCATATTGCTCTTCAGTCGACAAGGGAAATTACGGCT
ACAGAAATGGTACATCACTCTCCCTGATAAAGAGAGGAAGAAGATCACCCGGGAAATTGTTCAGATTATTCTCTCCCGTGGTCACAGGAC
AAGCAGTTTTGTTGACTGGAAGGAGCTAAAACTTGTTTATAAAAGGTATGCTAGTTTATATTTTTGCTGTGCAATAGAAAATCAGGACAA

>98821_98821_4_WDFY1-AP1S3_WDFY1_chr2_224749365_ENST00000233055_AP1S3_chr2_224642586_ENST00000423110_length(amino acids)=415AA_BP=0
MAAEIHSRPQSSRPVLLSKIEGHQDAVTAALLIPKEDGVITASEDRTIRVWLKRDSGQYWPSIYHTMASPCSAMAYHHDSRRIFVGQDNG
AVMEFHVSEDFNKMNFIKTYPAHQNRVSAIIFSLATEWVISTGHDKCVSWMCTRSGNMLGRHFFTSWASCLQYDFDTQYAFVGDYSGQIT
LLKLEQNTCSVITTLKGHEGSVACLWWDPIQRLLFSGASDNSIIMWDIGGRKGRTLLLQGHHDKVQSLCYLQLTRQLVSCSSDGGIAVWN
MDVSREEAPQWLESDSCQKCEQPFFWNIKQMWDTKTLGLRQIHFILLFSRQGKLRLQKWYITLPDKERKKITREIVQIILSRGHRTSSFV

--------------------------------------------------------------
>98821_98821_5_WDFY1-AP1S3_WDFY1_chr2_224749365_ENST00000233055_AP1S3_chr2_224642586_ENST00000443700_length(transcript)=2666nt_BP=1036nt
AAGAGGCCCCAGCAGCCGAAGGGAAACCGGCGCGTCCCCCGCCCGCCCAGGCGTCAGCTGATGGGCTGCCTGCCGAGGAGGCCGCAGCAG
TCGCCGCGCGAACATGGCGGCCGAAATCCACTCCAGGCCGCAGAGCAGCCGCCCGGTGCTGCTGAGCAAGATCGAGGGGCACCAGGACGC
CGTCACGGCCGCGCTGCTCATCCCCAAGGAGGACGGCGTGATCACGGCCAGCGAGGACAGAACCATCCGGGTATGGCTGAAAAGAGACAG
TGGTCAATACTGGCCCAGCATTTACCACACAATGGCCTCTCCTTGCTCTGCTATGGCTTACCATCATGACAGCAGACGGATATTTGTGGG
CCAGGATAATGGAGCTGTAATGGAATTTCACGTTTCTGAAGATTTTAATAAAATGAACTTTATCAAGACCTACCCAGCTCATCAGAACCG
GGTGTCTGCGATTATCTTCAGCTTGGCCACAGAGTGGGTGATCAGTACCGGCCACGACAAGTGTGTGAGCTGGATGTGCACGCGGAGCGG
GAACATGCTCGGGAGGCACTTCTTCACGTCCTGGGCTTCGTGTCTGCAATATGACTTTGACACTCAGTATGCTTTCGTTGGTGATTATTC
TGGGCAGATCACCCTGCTGAAGCTTGAACAGAACACGTGTTCAGTCATCACAACCCTCAAAGGACATGAAGGTAGTGTCGCCTGCCTCTG
GTGGGACCCTATTCAGCGGTTACTCTTCTCAGGAGCATCTGACAACAGCATCATCATGTGGGACATCGGAGGAAGGAAAGGCCGGACGCT
GTTACTTCAGGGCCATCATGACAAGGTGCAGTCGCTGTGCTACCTTCAGCTCACCAGGCAGCTCGTCTCCTGTTCCTCGGACGGCGGAAT
TGCAGTGTGGAACATGGATGTTAGCAGAGAAGAGGCTCCTCAGTGGTTGGAAAGTGATTCTTGTCAGAAATGTGAGCAGCCATTTTTCTG
GAACATAAAGCAGATGTGGGACACCAAGACGCTGGGGCTAAGACAAATACATTTCATATTGCTCTTCAGTCGACAAGGGAAATTACGGCT
ACAGAAATGGTACATCACTCTCCCTGATAAAGAGAGGAAGAAGATCACCCGGGAAATTGTTCAGATTATTCTCTCCCGTGGTCACAGGAC
AAGCAGTTTTGTTGACTGGAAGGAGCTAAAACTTGTTTATAAAAGGTATGCTAGTTTATATTTTTGCTGTGCAATAGAAAATCAGGACAA
TGAGCTCTTGACGCTAGAGATTGTGCATCGTTACGTGGAGCTGCTGGACAAATATTTTGGAAATGTCTGTGAGCTGGATATTATCTTTAA
TTTTGAAAAGGCTTATTTCATCCTGGACGAGTTTATAATAGGTGGGGAAATTCAGGAAACATCCAAGAAAATTGCTGTCAAAGCCATTGA
AGACTCTGATATGTTACAGGAGAATCGTTTGAGCCCCAGAGGCAGAGATTGCAGTGAGCCGAGATCATGCCATTGCACTCTAGCCTAGGC
AACAAGAGCAAAACTCCATCTAAAAAAAAAAAAAAAGAAAAGAAAAAGGAGAATTATGAAGAACTTGGTTCCACAAGTAAGATAGTCCTC
ATACTGCATCAGTAGTGACTTAAACTTTTTTAAAACTTTTATTTTTTGTGGGGGGATCTGTTGAATTTGGGAAGCCTCCAGTTTTAATAA
AATTTTTTTATTATGGTGGAAACATGTCTGTAAAACTTAGGACTATAGAAATGCAAAGAATAAAGAACTGAGGGAGTTACACACATTTGT
AGTCAGAAATTAAGTTCAAAAAATAATTTAGGTCATTTGCATTTTTTAGTATGCAAAATAAATGGAAAAATTAAAGTGCAATAAAAATAT
AATTTGGGAAATGAATGCAGTAAAATTGAAAACATTGAAATATTATAATTTAATAAAATAAACTTCAAAAAATGTATGAAAATATAAGTA
TCTTTACTTATATAGGATTAAATATATTTCTGATAATCTGTCCTCTATAATGAATTGGTTTAATTATGTTTTTCTGTTTTTAGAAATGGG
CATCTTTTTATTTCTGGAAACAACTTTTTAATGAGATTTTATCAAACATTAGACTATGACTAATTATAATATTCAAAGCCAATACCAAAA
CGATGGATAAATAAATGAATAAAACAAGGCACATTAATAGAAAAAAATGAATGAAATCAATTACGGGTTCTACTTGAAACACCTAATCTC
ATTATAATAGCAATAATAAAACAATTTGTACATACTTTATTAGTCGAACATTTATTAAAAATATAAGAGCATAGAGCAAATTAATTTGGA
AGAAAATTTAAATCTTTTACATACAAATACCCTCAAGAATAATAAATCATGGAGTATTAATAAAATTAAACCAGCTGATAATTTTAGAAA
GTGCTTCATGCACAGAGACTTTTATTCAAGTCCTCTTTGCTTTCTGCTAGTGCTTTTTTTTTTTTCTTGAAATGGGATGGGATCTCACTC
TGTCACCCAGGCTGGAGTGCAGTAGCACGATAGCAGCGCACTGCAACCTGGACCTCCTGGGCTCAAGCAATCCTCTCACCGCAGCCTCCT

>98821_98821_5_WDFY1-AP1S3_WDFY1_chr2_224749365_ENST00000233055_AP1S3_chr2_224642586_ENST00000443700_length(amino acids)=474AA_BP=0
MAAEIHSRPQSSRPVLLSKIEGHQDAVTAALLIPKEDGVITASEDRTIRVWLKRDSGQYWPSIYHTMASPCSAMAYHHDSRRIFVGQDNG
AVMEFHVSEDFNKMNFIKTYPAHQNRVSAIIFSLATEWVISTGHDKCVSWMCTRSGNMLGRHFFTSWASCLQYDFDTQYAFVGDYSGQIT
LLKLEQNTCSVITTLKGHEGSVACLWWDPIQRLLFSGASDNSIIMWDIGGRKGRTLLLQGHHDKVQSLCYLQLTRQLVSCSSDGGIAVWN
MDVSREEAPQWLESDSCQKCEQPFFWNIKQMWDTKTLGLRQIHFILLFSRQGKLRLQKWYITLPDKERKKITREIVQIILSRGHRTSSFV
DWKELKLVYKRYASLYFCCAIENQDNELLTLEIVHRYVELLDKYFGNVCELDIIFNFEKAYFILDEFIIGGEIQETSKKIAVKAIEDSDM

--------------------------------------------------------------
>98821_98821_6_WDFY1-AP1S3_WDFY1_chr2_224749365_ENST00000233055_AP1S3_chr2_224642586_ENST00000446015_length(transcript)=1498nt_BP=1036nt
AAGAGGCCCCAGCAGCCGAAGGGAAACCGGCGCGTCCCCCGCCCGCCCAGGCGTCAGCTGATGGGCTGCCTGCCGAGGAGGCCGCAGCAG
TCGCCGCGCGAACATGGCGGCCGAAATCCACTCCAGGCCGCAGAGCAGCCGCCCGGTGCTGCTGAGCAAGATCGAGGGGCACCAGGACGC
CGTCACGGCCGCGCTGCTCATCCCCAAGGAGGACGGCGTGATCACGGCCAGCGAGGACAGAACCATCCGGGTATGGCTGAAAAGAGACAG
TGGTCAATACTGGCCCAGCATTTACCACACAATGGCCTCTCCTTGCTCTGCTATGGCTTACCATCATGACAGCAGACGGATATTTGTGGG
CCAGGATAATGGAGCTGTAATGGAATTTCACGTTTCTGAAGATTTTAATAAAATGAACTTTATCAAGACCTACCCAGCTCATCAGAACCG
GGTGTCTGCGATTATCTTCAGCTTGGCCACAGAGTGGGTGATCAGTACCGGCCACGACAAGTGTGTGAGCTGGATGTGCACGCGGAGCGG
GAACATGCTCGGGAGGCACTTCTTCACGTCCTGGGCTTCGTGTCTGCAATATGACTTTGACACTCAGTATGCTTTCGTTGGTGATTATTC
TGGGCAGATCACCCTGCTGAAGCTTGAACAGAACACGTGTTCAGTCATCACAACCCTCAAAGGACATGAAGGTAGTGTCGCCTGCCTCTG
GTGGGACCCTATTCAGCGGTTACTCTTCTCAGGAGCATCTGACAACAGCATCATCATGTGGGACATCGGAGGAAGGAAAGGCCGGACGCT
GTTACTTCAGGGCCATCATGACAAGGTGCAGTCGCTGTGCTACCTTCAGCTCACCAGGCAGCTCGTCTCCTGTTCCTCGGACGGCGGAAT
TGCAGTGTGGAACATGGATGTTAGCAGAGAAGAGGCTCCTCAGTGGTTGGAAAGTGATTCTTGTCAGAAATGTGAGCAGCCATTTTTCTG
GAACATAAAGCAGATGTGGGACACCAAGACGCTGGGGCTAAGACAAATACATTTCATATTGCTCTTCAGTCGACAAGGGAAATTACGGCT
ACAGAAATGGTACATCACTCTCCCTGATAAAGAGAGGAAGAAGATCACCCGGGAAATTGTTCAGATTATTCTCTCCCGTGGTCACAGGAC
AAGCAGTTTTGTTGACTGGAAGGAGCTAAAACTTGTTTATAAAAGGTATGCTAGTTTATATTTTTGCTGTGCAATAGAAAATCAGGACAA
TGAGCTCTTGACGCTAGAGATTGTGCATCGTTACGTGGAGCTGCTGGACAAATATTTTGGAAATGTCTGTGAGCTGGATATTATCTTTAA
TTTTGAAAAGGCTTATTTCATCCTGGACGAGTTTATAATAGGTGGGGAAATTCAGGAAACATCCAAGAAAATTGCTGTCAAAGCCATTGA

>98821_98821_6_WDFY1-AP1S3_WDFY1_chr2_224749365_ENST00000233055_AP1S3_chr2_224642586_ENST00000446015_length(amino acids)=465AA_BP=0
MAAEIHSRPQSSRPVLLSKIEGHQDAVTAALLIPKEDGVITASEDRTIRVWLKRDSGQYWPSIYHTMASPCSAMAYHHDSRRIFVGQDNG
AVMEFHVSEDFNKMNFIKTYPAHQNRVSAIIFSLATEWVISTGHDKCVSWMCTRSGNMLGRHFFTSWASCLQYDFDTQYAFVGDYSGQIT
LLKLEQNTCSVITTLKGHEGSVACLWWDPIQRLLFSGASDNSIIMWDIGGRKGRTLLLQGHHDKVQSLCYLQLTRQLVSCSSDGGIAVWN
MDVSREEAPQWLESDSCQKCEQPFFWNIKQMWDTKTLGLRQIHFILLFSRQGKLRLQKWYITLPDKERKKITREIVQIILSRGHRTSSFV
DWKELKLVYKRYASLYFCCAIENQDNELLTLEIVHRYVELLDKYFGNVCELDIIFNFEKAYFILDEFIIGGEIQETSKKIAVKAIEDSDM

--------------------------------------------------------------
>98821_98821_7_WDFY1-AP1S3_WDFY1_chr2_224809865_ENST00000233055_AP1S3_chr2_224642586_ENST00000396653_length(transcript)=694nt_BP=240nt
AAGAGGCCCCAGCAGCCGAAGGGAAACCGGCGCGTCCCCCGCCCGCCCAGGCGTCAGCTGATGGGCTGCCTGCCGAGGAGGCCGCAGCAG
TCGCCGCGCGAACATGGCGGCCGAAATCCACTCCAGGCCGCAGAGCAGCCGCCCGGTGCTGCTGAGCAAGATCGAGGGGCACCAGGACGC
CGTCACGGCCGCGCTGCTCATCCCCAAGGAGGACGGCGTGATCACGGCCAGCGAGGACAGATACATTTCATATTGCTCTTCAGTCGACAA
GGGAAATTACGGCTACAGAAATGGTACATCACTCTCCCTGATAAAGAGAGGAAGAAGATCACCCGGGAAATTGTTCAGATTATTCTCTCC
CGTGGTCACAGGACAAGCAGTTTTGTTGACTGGAAGGAGCTAAAACTTGTTTATAAAAGGTGTCTGTGAGCTGGATATTATCTTTAATTT
TGAAAAGGCTTATTTCATCCTGGACGAGTTTATAATAGGTGGGGAAATTCAGGAAACATCCAAGAAAATTGCTGTCAAAGCCATTGAAGA
CTCTGATATGTTACAGGAGGTCAGTACGGTTTCCCAAACCATGGGAGAAAGATGATGATGATGATGATGATGGTGTTAATAATTATAATA

>98821_98821_7_WDFY1-AP1S3_WDFY1_chr2_224809865_ENST00000233055_AP1S3_chr2_224642586_ENST00000396653_length(amino acids)=123AA_BP=1
MMGCLPRRPQQSPREHGGRNPLQAAEQPPGAAEQDRGAPGRRHGRAAHPQGGRRDHGQRGQIHFILLFSRQGKLRLQKWYITLPDKERKK

--------------------------------------------------------------
>98821_98821_8_WDFY1-AP1S3_WDFY1_chr2_224809865_ENST00000233055_AP1S3_chr2_224642586_ENST00000396654_length(transcript)=935nt_BP=240nt
AAGAGGCCCCAGCAGCCGAAGGGAAACCGGCGCGTCCCCCGCCCGCCCAGGCGTCAGCTGATGGGCTGCCTGCCGAGGAGGCCGCAGCAG
TCGCCGCGCGAACATGGCGGCCGAAATCCACTCCAGGCCGCAGAGCAGCCGCCCGGTGCTGCTGAGCAAGATCGAGGGGCACCAGGACGC
CGTCACGGCCGCGCTGCTCATCCCCAAGGAGGACGGCGTGATCACGGCCAGCGAGGACAGATACATTTCATATTGCTCTTCAGTCGACAA
GGGAAATTACGGCTACAGAAATGGTACATCACTCTCCCTGATAAAGAGAGGAAGAAGATCACCCGGGAAATTGTTCAGATTATTCTCTCC
CGTGGTCACAGGACAAGCAGTTTTGTTGACTGGAAGGAGCTAAAACTTGTTTATAAAAGGTATGCTAGTTTATATTTTTGCTGTGCAATA
GAAAATCAGGACAATGAGCTCTTGACGCTAGAGATTGTGCATCGTTACGTGGAGCTGCTGGACAAATATTTTGGAAATGTCTGTGAGCTG
GATATTATCTTTAATTTTGAAAAGGCTTATTTCATCCTGGACGAGTTTATAATAGGTGGGGAAATTCAGGAAACATCCAAGAAAATTGCT
GTCAAAGCCATTGAAGACTCTGATATGTTACAGGAGACAATGGAAGAATACATGAACAAGCCTACATTTTAACTGGAAATCTACTTGAAG
ACTCCAGCACTACATGTTATGAAGCTGTAAATAAGCAACGCCTCCCATCCGGTTTTTTGATGGAGCCTCAGGCACCATGCCAAAAATAAT
TTAAAGGGATTCTTTGTTAACTAACAAAGTTAAAGTTGTTTAACATATTTATAATTACTATGTGTCTGTATTATTAAAAAAAATTATGTG

>98821_98821_8_WDFY1-AP1S3_WDFY1_chr2_224809865_ENST00000233055_AP1S3_chr2_224642586_ENST00000396654_length(amino acids)=214AA_BP=1
MMGCLPRRPQQSPREHGGRNPLQAAEQPPGAAEQDRGAPGRRHGRAAHPQGGRRDHGQRGQIHFILLFSRQGKLRLQKWYITLPDKERKK
ITREIVQIILSRGHRTSSFVDWKELKLVYKRYASLYFCCAIENQDNELLTLEIVHRYVELLDKYFGNVCELDIIFNFEKAYFILDEFIIG

--------------------------------------------------------------
>98821_98821_9_WDFY1-AP1S3_WDFY1_chr2_224809865_ENST00000233055_AP1S3_chr2_224642586_ENST00000409375_length(transcript)=698nt_BP=240nt
AAGAGGCCCCAGCAGCCGAAGGGAAACCGGCGCGTCCCCCGCCCGCCCAGGCGTCAGCTGATGGGCTGCCTGCCGAGGAGGCCGCAGCAG
TCGCCGCGCGAACATGGCGGCCGAAATCCACTCCAGGCCGCAGAGCAGCCGCCCGGTGCTGCTGAGCAAGATCGAGGGGCACCAGGACGC
CGTCACGGCCGCGCTGCTCATCCCCAAGGAGGACGGCGTGATCACGGCCAGCGAGGACAGATACATTTCATATTGCTCTTCAGTCGACAA
GGGAAATTACGGCTACAGAAATGGTACATCACTCTCCCTGATAAAGAGAGGAAGAAGATCACCCGGGAAATTGTTCAGATTATTCTCTCC
CGTGGTCACAGGACAAGCAGTTTTGTTGACTGGAAGGAGCTAAAACTTGTTTATAAAAGGTATGCTAGTTTATATTTTTGCTGTGCAATA
GAAAATCAGGACAATGAGCTCTTGACGCTAGAGATTGTGCATCGTTACGTGGAGCTGCTGGACAAATATTTTGGAAATGAGTTTAATTGC
TGGTTTCTCCTAATGAGGCTCCTGTCTGTCTTGGATTCCTGGTCTACGCCTGCCTTGAACTCCGAGGTTCCTCAGCTTGCTACTATAACT

>98821_98821_9_WDFY1-AP1S3_WDFY1_chr2_224809865_ENST00000233055_AP1S3_chr2_224642586_ENST00000409375_length(amino acids)=197AA_BP=1
MMGCLPRRPQQSPREHGGRNPLQAAEQPPGAAEQDRGAPGRRHGRAAHPQGGRRDHGQRGQIHFILLFSRQGKLRLQKWYITLPDKERKK
ITREIVQIILSRGHRTSSFVDWKELKLVYKRYASLYFCCAIENQDNELLTLEIVHRYVELLDKYFGNEFNCWFLLMRLLSVLDSWSTPAL

--------------------------------------------------------------
>98821_98821_10_WDFY1-AP1S3_WDFY1_chr2_224809865_ENST00000233055_AP1S3_chr2_224642586_ENST00000423110_length(transcript)=552nt_BP=240nt
AAGAGGCCCCAGCAGCCGAAGGGAAACCGGCGCGTCCCCCGCCCGCCCAGGCGTCAGCTGATGGGCTGCCTGCCGAGGAGGCCGCAGCAG
TCGCCGCGCGAACATGGCGGCCGAAATCCACTCCAGGCCGCAGAGCAGCCGCCCGGTGCTGCTGAGCAAGATCGAGGGGCACCAGGACGC
CGTCACGGCCGCGCTGCTCATCCCCAAGGAGGACGGCGTGATCACGGCCAGCGAGGACAGATACATTTCATATTGCTCTTCAGTCGACAA
GGGAAATTACGGCTACAGAAATGGTACATCACTCTCCCTGATAAAGAGAGGAAGAAGATCACCCGGGAAATTGTTCAGATTATTCTCTCC
CGTGGTCACAGGACAAGCAGTTTTGTTGACTGGAAGGAGCTAAAACTTGTTTATAAAAGGTATGCTAGTTTATATTTTTGCTGTGCAATA
GAAAATCAGGACAATGAGCTCTTGACGCTAGAGATTGTGCATCGTTACGTGGAGCTGCTGGACAAATATTTTGGAAATACTTGGCCTTTT

>98821_98821_10_WDFY1-AP1S3_WDFY1_chr2_224809865_ENST00000233055_AP1S3_chr2_224642586_ENST00000423110_length(amino acids)=164AA_BP=1
MMGCLPRRPQQSPREHGGRNPLQAAEQPPGAAEQDRGAPGRRHGRAAHPQGGRRDHGQRGQIHFILLFSRQGKLRLQKWYITLPDKERKK

--------------------------------------------------------------
>98821_98821_11_WDFY1-AP1S3_WDFY1_chr2_224809865_ENST00000233055_AP1S3_chr2_224642586_ENST00000443700_length(transcript)=1870nt_BP=240nt
AAGAGGCCCCAGCAGCCGAAGGGAAACCGGCGCGTCCCCCGCCCGCCCAGGCGTCAGCTGATGGGCTGCCTGCCGAGGAGGCCGCAGCAG
TCGCCGCGCGAACATGGCGGCCGAAATCCACTCCAGGCCGCAGAGCAGCCGCCCGGTGCTGCTGAGCAAGATCGAGGGGCACCAGGACGC
CGTCACGGCCGCGCTGCTCATCCCCAAGGAGGACGGCGTGATCACGGCCAGCGAGGACAGATACATTTCATATTGCTCTTCAGTCGACAA
GGGAAATTACGGCTACAGAAATGGTACATCACTCTCCCTGATAAAGAGAGGAAGAAGATCACCCGGGAAATTGTTCAGATTATTCTCTCC
CGTGGTCACAGGACAAGCAGTTTTGTTGACTGGAAGGAGCTAAAACTTGTTTATAAAAGGTATGCTAGTTTATATTTTTGCTGTGCAATA
GAAAATCAGGACAATGAGCTCTTGACGCTAGAGATTGTGCATCGTTACGTGGAGCTGCTGGACAAATATTTTGGAAATGTCTGTGAGCTG
GATATTATCTTTAATTTTGAAAAGGCTTATTTCATCCTGGACGAGTTTATAATAGGTGGGGAAATTCAGGAAACATCCAAGAAAATTGCT
GTCAAAGCCATTGAAGACTCTGATATGTTACAGGAGAATCGTTTGAGCCCCAGAGGCAGAGATTGCAGTGAGCCGAGATCATGCCATTGC
ACTCTAGCCTAGGCAACAAGAGCAAAACTCCATCTAAAAAAAAAAAAAAAGAAAAGAAAAAGGAGAATTATGAAGAACTTGGTTCCACAA
GTAAGATAGTCCTCATACTGCATCAGTAGTGACTTAAACTTTTTTAAAACTTTTATTTTTTGTGGGGGGATCTGTTGAATTTGGGAAGCC
TCCAGTTTTAATAAAATTTTTTTATTATGGTGGAAACATGTCTGTAAAACTTAGGACTATAGAAATGCAAAGAATAAAGAACTGAGGGAG
TTACACACATTTGTAGTCAGAAATTAAGTTCAAAAAATAATTTAGGTCATTTGCATTTTTTAGTATGCAAAATAAATGGAAAAATTAAAG
TGCAATAAAAATATAATTTGGGAAATGAATGCAGTAAAATTGAAAACATTGAAATATTATAATTTAATAAAATAAACTTCAAAAAATGTA
TGAAAATATAAGTATCTTTACTTATATAGGATTAAATATATTTCTGATAATCTGTCCTCTATAATGAATTGGTTTAATTATGTTTTTCTG
TTTTTAGAAATGGGCATCTTTTTATTTCTGGAAACAACTTTTTAATGAGATTTTATCAAACATTAGACTATGACTAATTATAATATTCAA
AGCCAATACCAAAACGATGGATAAATAAATGAATAAAACAAGGCACATTAATAGAAAAAAATGAATGAAATCAATTACGGGTTCTACTTG
AAACACCTAATCTCATTATAATAGCAATAATAAAACAATTTGTACATACTTTATTAGTCGAACATTTATTAAAAATATAAGAGCATAGAG
CAAATTAATTTGGAAGAAAATTTAAATCTTTTACATACAAATACCCTCAAGAATAATAAATCATGGAGTATTAATAAAATTAAACCAGCT
GATAATTTTAGAAAGTGCTTCATGCACAGAGACTTTTATTCAAGTCCTCTTTGCTTTCTGCTAGTGCTTTTTTTTTTTTCTTGAAATGGG
ATGGGATCTCACTCTGTCACCCAGGCTGGAGTGCAGTAGCACGATAGCAGCGCACTGCAACCTGGACCTCCTGGGCTCAAGCAATCCTCT

>98821_98821_11_WDFY1-AP1S3_WDFY1_chr2_224809865_ENST00000233055_AP1S3_chr2_224642586_ENST00000443700_length(amino acids)=224AA_BP=1
MMGCLPRRPQQSPREHGGRNPLQAAEQPPGAAEQDRGAPGRRHGRAAHPQGGRRDHGQRGQIHFILLFSRQGKLRLQKWYITLPDKERKK
ITREIVQIILSRGHRTSSFVDWKELKLVYKRYASLYFCCAIENQDNELLTLEIVHRYVELLDKYFGNVCELDIIFNFEKAYFILDEFIIG

--------------------------------------------------------------
>98821_98821_12_WDFY1-AP1S3_WDFY1_chr2_224809865_ENST00000233055_AP1S3_chr2_224642586_ENST00000446015_length(transcript)=702nt_BP=240nt
AAGAGGCCCCAGCAGCCGAAGGGAAACCGGCGCGTCCCCCGCCCGCCCAGGCGTCAGCTGATGGGCTGCCTGCCGAGGAGGCCGCAGCAG
TCGCCGCGCGAACATGGCGGCCGAAATCCACTCCAGGCCGCAGAGCAGCCGCCCGGTGCTGCTGAGCAAGATCGAGGGGCACCAGGACGC
CGTCACGGCCGCGCTGCTCATCCCCAAGGAGGACGGCGTGATCACGGCCAGCGAGGACAGATACATTTCATATTGCTCTTCAGTCGACAA
GGGAAATTACGGCTACAGAAATGGTACATCACTCTCCCTGATAAAGAGAGGAAGAAGATCACCCGGGAAATTGTTCAGATTATTCTCTCC
CGTGGTCACAGGACAAGCAGTTTTGTTGACTGGAAGGAGCTAAAACTTGTTTATAAAAGGTATGCTAGTTTATATTTTTGCTGTGCAATA
GAAAATCAGGACAATGAGCTCTTGACGCTAGAGATTGTGCATCGTTACGTGGAGCTGCTGGACAAATATTTTGGAAATGTCTGTGAGCTG
GATATTATCTTTAATTTTGAAAAGGCTTATTTCATCCTGGACGAGTTTATAATAGGTGGGGAAATTCAGGAAACATCCAAGAAAATTGCT

>98821_98821_12_WDFY1-AP1S3_WDFY1_chr2_224809865_ENST00000233055_AP1S3_chr2_224642586_ENST00000446015_length(amino acids)=214AA_BP=1
MMGCLPRRPQQSPREHGGRNPLQAAEQPPGAAEQDRGAPGRRHGRAAHPQGGRRDHGQRGQIHFILLFSRQGKLRLQKWYITLPDKERKK
ITREIVQIILSRGHRTSSFVDWKELKLVYKRYASLYFCCAIENQDNELLTLEIVHRYVELLDKYFGNVCELDIIFNFEKAYFILDEFIIG

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Fusion Gene PPI Analysis for WDFY1-AP1S3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for WDFY1-AP1S3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for WDFY1-AP1S3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource