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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:WDR90-ESYT3 (FusionGDB2 ID:99133)

Fusion Gene Summary for WDR90-ESYT3

check button Fusion gene summary
Fusion gene informationFusion gene name: WDR90-ESYT3
Fusion gene ID: 99133
HgeneTgene
Gene symbol

WDR90

ESYT3

Gene ID

197335

83850

Gene nameWD repeat domain 90extended synaptotagmin 3
SynonymsC16orf15|C16orf16|C16orf17|C16orf18|C16orf19|POC16CHR3SYT|E-Syt3|FAM62C
Cytomap

16p13.3

3q22.3

Type of geneprotein-codingprotein-coding
DescriptionWD repeat-containing protein 90extended synaptotagmin-3chr3 synaptotagminextended synaptotagmin protein 3family with sequence similarity 62 (C2 domain containing), member C
Modification date2020031320200313
UniProtAcc.

A0FGR9

Ensembl transtripts involved in fusion geneENST00000293879, ENST00000549091, 
ENST00000315764, ENST00000547543, 
ENST00000547944, 		ENST00000460133, 
ENST00000289135, ENST00000389567, 
Fusion gene scores* DoF score2 X 2 X 2=83 X 3 X 3=27
# samples 23
** MAII scorelog2(2/8*10)=1.32192809488736log2(3/27*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: WDR90 [Title/Abstract] AND ESYT3 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointWDR90(712331)-ESYT3(138195065), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across WDR90 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ESYT3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SARCTCGA-DX-A8BS-01AWDR90chr16

712331

-ESYT3chr3

138195065

+


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Fusion Gene ORF analysis for WDR90-ESYT3

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000293879ENST00000460133WDR90chr16

712331

-ESYT3chr3

138195065

+
5CDS-3UTRENST00000549091ENST00000460133WDR90chr16

712331

-ESYT3chr3

138195065

+
5CDS-intronENST00000293879ENST00000289135WDR90chr16

712331

-ESYT3chr3

138195065

+
5CDS-intronENST00000549091ENST00000289135WDR90chr16

712331

-ESYT3chr3

138195065

+
In-frameENST00000293879ENST00000389567WDR90chr16

712331

-ESYT3chr3

138195065

+
In-frameENST00000549091ENST00000389567WDR90chr16

712331

-ESYT3chr3

138195065

+
intron-3CDSENST00000315764ENST00000389567WDR90chr16

712331

-ESYT3chr3

138195065

+
intron-3CDSENST00000547543ENST00000389567WDR90chr16

712331

-ESYT3chr3

138195065

+
intron-3CDSENST00000547944ENST00000389567WDR90chr16

712331

-ESYT3chr3

138195065

+
intron-3UTRENST00000315764ENST00000460133WDR90chr16

712331

-ESYT3chr3

138195065

+
intron-3UTRENST00000547543ENST00000460133WDR90chr16

712331

-ESYT3chr3

138195065

+
intron-3UTRENST00000547944ENST00000460133WDR90chr16

712331

-ESYT3chr3

138195065

+
intron-intronENST00000315764ENST00000289135WDR90chr16

712331

-ESYT3chr3

138195065

+
intron-intronENST00000547543ENST00000289135WDR90chr16

712331

-ESYT3chr3

138195065

+
intron-intronENST00000547944ENST00000289135WDR90chr16

712331

-ESYT3chr3

138195065

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000549091WDR90chr16712331-ENST00000389567ESYT3chr3138195065+599042379244291445
ENST00000293879WDR90chr16712331-ENST00000389567ESYT3chr3138195065+58984145043371445

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000549091ENST00000389567WDR90chr16712331-ESYT3chr3138195065+0.0042234720.9957766
ENST00000293879ENST00000389567WDR90chr16712331-ESYT3chr3138195065+0.0037798570.9962202

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Fusion Genomic Features for WDR90-ESYT3


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for WDR90-ESYT3


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr16:712331/chr3:138195065)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.ESYT3

A0FGR9

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport (By similarity). Tethers the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane. {ECO:0000250, ECO:0000269|PubMed:23791178}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneWDR90chr16:712331chr3:138195065ENST00000293879-33411156_120113811749.0RepeatNote=WD 12
HgeneWDR90chr16:712331chr3:138195065ENST00000293879-33411204_124513811749.0RepeatNote=WD 13
HgeneWDR90chr16:712331chr3:138195065ENST00000293879-33411247_128613811749.0RepeatNote=WD 14
HgeneWDR90chr16:712331chr3:138195065ENST00000293879-33411298_132613811749.0RepeatNote=WD 15
HgeneWDR90chr16:712331chr3:138195065ENST00000293879-33411327_137613811749.0RepeatNote=WD 16
HgeneWDR90chr16:712331chr3:138195065ENST00000293879-3341407_45013811749.0RepeatNote=WD 1
HgeneWDR90chr16:712331chr3:138195065ENST00000293879-3341452_49413811749.0RepeatNote=WD 2
HgeneWDR90chr16:712331chr3:138195065ENST00000293879-3341501_54113811749.0RepeatNote=WD 3
HgeneWDR90chr16:712331chr3:138195065ENST00000293879-3341615_65413811749.0RepeatNote=WD 4
HgeneWDR90chr16:712331chr3:138195065ENST00000293879-3341656_69513811749.0RepeatNote=WD 5
HgeneWDR90chr16:712331chr3:138195065ENST00000293879-3341698_73713811749.0RepeatNote=WD 6
HgeneWDR90chr16:712331chr3:138195065ENST00000293879-3341740_77913811749.0RepeatNote=WD 7
HgeneWDR90chr16:712331chr3:138195065ENST00000293879-3341782_82113811749.0RepeatNote=WD 8
HgeneWDR90chr16:712331chr3:138195065ENST00000293879-3341882_92213811749.0RepeatNote=WD 9
HgeneWDR90chr16:712331chr3:138195065ENST00000293879-3341926_96413811749.0RepeatNote=WD 10
HgeneWDR90chr16:712331chr3:138195065ENST00000293879-3341969_100913811749.0RepeatNote=WD 11

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneWDR90chr16:712331chr3:138195065ENST00000293879-33411433_147213811749.0RepeatNote=WD 17
HgeneWDR90chr16:712331chr3:138195065ENST00000293879-33411475_152013811749.0RepeatNote=WD 18
HgeneWDR90chr16:712331chr3:138195065ENST00000293879-33411523_156213811749.0RepeatNote=WD 19
HgeneWDR90chr16:712331chr3:138195065ENST00000293879-33411568_161413811749.0RepeatNote=WD 20
HgeneWDR90chr16:712331chr3:138195065ENST00000293879-33411715_174813811749.0RepeatNote=WD 21
HgeneWDR90chr16:712331chr3:138195065ENST00000315764-161156_12010300.0RepeatNote=WD 12
HgeneWDR90chr16:712331chr3:138195065ENST00000315764-161204_12450300.0RepeatNote=WD 13
HgeneWDR90chr16:712331chr3:138195065ENST00000315764-161247_12860300.0RepeatNote=WD 14
HgeneWDR90chr16:712331chr3:138195065ENST00000315764-161298_13260300.0RepeatNote=WD 15
HgeneWDR90chr16:712331chr3:138195065ENST00000315764-161327_13760300.0RepeatNote=WD 16
HgeneWDR90chr16:712331chr3:138195065ENST00000315764-161433_14720300.0RepeatNote=WD 17
HgeneWDR90chr16:712331chr3:138195065ENST00000315764-161475_15200300.0RepeatNote=WD 18
HgeneWDR90chr16:712331chr3:138195065ENST00000315764-161523_15620300.0RepeatNote=WD 19
HgeneWDR90chr16:712331chr3:138195065ENST00000315764-161568_16140300.0RepeatNote=WD 20
HgeneWDR90chr16:712331chr3:138195065ENST00000315764-161715_17480300.0RepeatNote=WD 21
HgeneWDR90chr16:712331chr3:138195065ENST00000315764-16407_4500300.0RepeatNote=WD 1
HgeneWDR90chr16:712331chr3:138195065ENST00000315764-16452_4940300.0RepeatNote=WD 2
HgeneWDR90chr16:712331chr3:138195065ENST00000315764-16501_5410300.0RepeatNote=WD 3
HgeneWDR90chr16:712331chr3:138195065ENST00000315764-16615_6540300.0RepeatNote=WD 4
HgeneWDR90chr16:712331chr3:138195065ENST00000315764-16656_6950300.0RepeatNote=WD 5
HgeneWDR90chr16:712331chr3:138195065ENST00000315764-16698_7370300.0RepeatNote=WD 6
HgeneWDR90chr16:712331chr3:138195065ENST00000315764-16740_7790300.0RepeatNote=WD 7
HgeneWDR90chr16:712331chr3:138195065ENST00000315764-16782_8210300.0RepeatNote=WD 8
HgeneWDR90chr16:712331chr3:138195065ENST00000315764-16882_9220300.0RepeatNote=WD 9
HgeneWDR90chr16:712331chr3:138195065ENST00000315764-16926_9640300.0RepeatNote=WD 10
HgeneWDR90chr16:712331chr3:138195065ENST00000315764-16969_10090300.0RepeatNote=WD 11
TgeneESYT3chr16:712331chr3:138195065ENST000003895671923114_291822887.0DomainSMP-LTD
TgeneESYT3chr16:712331chr3:138195065ENST000003895671923291_408822887.0DomainC2 1
TgeneESYT3chr16:712331chr3:138195065ENST000003895671923426_566822887.0DomainC2 2
TgeneESYT3chr16:712331chr3:138195065ENST000003895671923754_876822887.0DomainC2 3
TgeneESYT3chr16:712331chr3:138195065ENST000003895671923801_808822887.0RegionRequired for phosphatidylinositol 4%2C5-bisphosphate-dependent location at the cell membrane
TgeneESYT3chr16:712331chr3:138195065ENST0000038956719231_29822887.0Topological domainCytoplasmic
TgeneESYT3chr16:712331chr3:138195065ENST00000389567192372_886822887.0Topological domainCytoplasmic
TgeneESYT3chr16:712331chr3:138195065ENST00000389567192330_50822887.0TransmembraneHelical
TgeneESYT3chr16:712331chr3:138195065ENST00000389567192351_71822887.0TransmembraneHelical


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Fusion Gene Sequence for WDR90-ESYT3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>99133_99133_1_WDR90-ESYT3_WDR90_chr16_712331_ENST00000293879_ESYT3_chr3_138195065_ENST00000389567_length(transcript)=5898nt_BP=4145nt
ATGGCCCGAGCGTGGCAGCACCCGTTCCTCAACGTCTTCAGACACTTCCGGGTGGACGAGTGGAAGCGCTCCGCCAAGCAGGGGGACGTG
GCCGTGGTCACGGACAAGACCCTGAAGGGCGCCGTGTATCGCATTCGGGGCTCAGTCTCTGCCGCCAACTACATCCAGCTCCCTAAGAGC
AGCACCCAGTCTCTGGGGCTGACGGGACGATACCTGTATGTGCTCTTTCGGCCCCTGCCCAGCAAGCACTTCGTCATCCACCTCGATGTG
TCCTCCAAGGACAACCAAGTCATCCGTGTGTCTTTCTCCAACCTCTTCAAGGAGTTTAAGTCTACGGCCACGTGGCTCCAGTTTCCCTTG
GTCCTGGAGGCCAGGACACCTCAGAGAGATCTGGTGGGTTTGGCCCCCTCCGGAGCCCGCTGGACCTGCCTGCAGCTCGATCTGCAGGAC
GTTCTCCTGGTCTACCTGAACCGGTGCTACGGCCATCTCAAGAGCATCAGGCTGTGCGCCAGCCTGCTGGTCAGGAACCTGTACACCAGT
GACCTGTGCTTTGAGCCTGCCATCTCTGGGGCCCAGTGGGCAAAGCTGCCCGTGACTCCTATGCCTCGGGAAATGGCATTCCCTGTGCCC
AAGGGAGAGAGCTGGCATGACCGCTACATCCACGTCCGGTTTCCAAGTGAGAGCTTGAAAGTGCCTTCCAAGCCGATTGAGAAGAGCTGT
TCCCCTCCTGAGGCAGTCCTCCTGGGGCCGGGGCCACAGCCTCTCCCTTGCCCGGTGGCCTCCAGCAAACCTGTGCGGTTCAGTGTGTCT
CCAGTGGTCCAGACGCCCAGCCCCACAGCCTCCGGCCGGGCCGCCTTGGCACCCAGGCCCTTCCCGGAGGTCAGCCTGTCCCAAGAGCGC
TCAGACGCCTCCAACGCGGATGGCCCCGGTTTCCATAGCCTTGAGCCCTGGGCCCAGCTGGAGGCCTCTGACATCCACACGGCTGCTGCC
GGCACCCACGTGTTGACTCACGAGTCGGCTGAGGTGCCCGTGGCCCGCACCGGCTCCTGCGAAGGCTTCCTCCCAGACCCAGTCCTGAGG
CTCAAGGGCGTCATCGGCTTTGGGGGCCACGGCACCAGACAGGCCCTGTGGACCCCAGACGGGGCGGCTGTCGTGTACCCCTGCCATGCG
GTCATCGTCGTCCTGCTCGTGGACACGGGGGAGCAGCGCTTCTTCCTTGGCCACACAGACAAGGTCTCCGCCCTGGCGCTGGATGGCAGC
AGCTCACTATTGGCCTCGGCCCAGGCAAGGGCCCCTAGTGTGATGCGGCTCTGGGACTTCCAGACCGGGCGGTGCTTGTGCCTGTTCCGG
AGCCCAATGCACGTTGTCTGCTCTCTCAGCTTCTCTGACAGCGGGGCCCTTCTCTGCGGGGTTGGCAAGGACCACCACGGGAGGACGATG
GTGGTGGCCTGGGGCACCGGCCAGGTGGGCCTCGGTGGCGAGGTGGTCGTTCTGGCAAAGGCGCACACTGACTTTGACGTCCAGGCCTTC
CGGGTCACCTTTTTTGATGAAACCAGGATGGCGTCGTGCGGGCAGGGCAGTGTGCGGCTCTGGCGGCTGCGTGGCGGGGTGCTGCGTTCC
TGCCCCGTGGACTTAGGGGAGCACCACGCGCTGCAGTTCACCGACCTGGCCTTCAAGCAGGCCCGGGACGGCTGCCCGGAGCCCTCGGCT
GCCATGCTCTTCGTGTGCAGCCGCAGTGGCCACATCTTGGAGATTGACTGTCAGCGCATGGTCGTGCGGCATGCCCGCCGCCTGCTCCCC
ACACGGACTCCAGGCGGTCCCCACCCACAGAAGCAGACCTTCAGCTCAGGCCCCGGCATTGCCATCAGCAGCCTCAGCGTCTCCCCGGCC
ATGTGTGCTGTGGGCTCTGAGGACGGCTTCTTGCGGCTCTGGCCCCTGGACTTCTCCTCGGTGCTCCTGGAGGCAGAGCACGAGGGCCCC
GTCAGCTCAGTCTGTGTCAGCCCCGATGGCCTCCGTGTGCTGTCTGCCACCTCCTCGGGCCACCTGGGCTTCCTGGACACGCTGTCCCGG
GTGTACCACATGCTGGCTCGCTCCCACACCGCCCCGGTGTTGGCCCTCGCCATGGAGCAGAGGCGGGGACAGCTGGCCACCGTGTCCCAG
GACCGTACCGTCCGCATCTGGGACCTGGCCACCCTGCAGCAGCTATACGACTTCACATCATCAGAGGACGCCCCGTGCGCTGTCACCTTC
CACCCCACAAGGCCAACCTTTTTCTGTGGCTTTAGCAGTGGGGCCGTGCGCTCCTTCAGCCTGGAGGCCGCTGAGGTCCTGGTGGAACAC
ACGTGCCACCGAGGAGCTGTCACCGGCCTGACCGCCACCCCTGACGGCCGCCTGCTCTTCAGCTCCTGCTCCCAGGGCTCCCTGGCCCAG
TACAGCTGTGCGGACCCCCAGTGGCATGTCCTCCGAGTGGCAGCGGACATGGTATGCCCGGATGCCCCCGCGAGCCCCAGCGCCCTGGCA
GTCAGCAGGGATGGCCGCCTGCTGGCCTTTGTGGGACCCTCCAGGTGCACAGTGACAGTCATGGGCTCGGCCTCCCTTGATGAGCTGCTG
CGAGTTGACATCGGCACTCTGGACCTGGCCAGCAGCCGCCTGGACTCAGCCATGGCTGTGTGCTTTGGCCCTGCAGCTCTGGGCCACCTG
CTGGTGTCCACCTCGTCCAACAGAGTCGTGGTGCTGGATGCTGTGTCGGGCCGCATCATCCGGGAGCTGCCCGGTGTCCACCCTGAGCCC
TGCCCCTCCTTGACGCTCAGTGAGGACGCCCGCTTCCTGCTGATTGCCGCCGGCCGGACCATCAAGGTGTGGGACTACGCCACACAGGCC
AGCCCAGGCCCCCAGGTGTACATCGGCCACTCGGAACCCGTGCAGGCTGTGGCCTTCTCTCCTGACCAGCAGCAGGTCCTCAGCGCAGGG
GACGCCGTCTTCCTCTGGGATGTCCTGGCCCCTACTGAGAGCGACCAAAGCTTCCCCGGGGCCCCCCCAGCCTGCAAGACAGGCCCGGGC
GCAGGACCGCTGGAGGACGCAGCGTCCAGGGCCAGCGAGCTCCCCCGGCAGCAGGTCCCCAAGCCATGTCAGGCATCTCCACCACGGCTG
GGCGTCTGTGCCAGGCCTCCCGAAGGTGGCGATGGCGCCAGGGACACCAGGAATTCGGGGGCCCCACGCACCACCTACCTGGCTTCCTGC
AAGGCCTTCACGCCTGCCAGGGTCAGCTGCAGCCCCCACTCTGCCAAGGGCACTTGCCCGCCTCCCGCCAGCGGTGGGTGGCTGCGTCTG
AAGGCTGTCGTCGGTTACAGCGGGAATGGGCGGGCCAACATGGTCTGGAGGCCGGACACAGGCTTCTTTGCCTACACGTGCGGCCGCCTG
GTGGTGGTGGAGGACCTGCACTCTGGCGCCCAGCAGCACTGGTCCGGCCACTCTGCGGAGATCTCCACGCTGGCCCTCAGCCACAGTGCC
CAGGTCCTGGCCTCTGCCTCGGGCCGAAGCAGCACGACCGCCCATTGTCAGATCCGCGTCTGGGACGTGTCTGGCGGCCTCTGCCAGCAT
CTCATTTTCCCCCATAGCACCACCGTGCTGGCCCTGGCCTTCTCACCAGATGACAGGCTTCTTGTCACACTGGGGGACCACGATGGCCGC
ACCCTCGCCCTGTGGGGCACGGCCACCTATGACCTCGTGTCCTCCACCCGCCTCCCGGAGCCGGTGCATGGTGTGGCCTTCAACCCCTGG
GACGCCGGCGAGCTCACCTGTGTGGGCCAGGGCACTGTCACCTTCTGGCTCCTTCAGCAGCGTGGGGCAGACATCAGCCTTCAGGTGCGT
CGAGAGCCAGTCCCAGAGGCAGTGGGGGCTGGAGAGCTGACCTCGCTCTGCTACGGGGCACCTCCCCTGCTCTATTGTGGCACCAGCTCT
GGCCAGGTCTGTGTCTGGGACACGCGTGCCGGCCGCTGCTTCTTGTCCTGGGAGGCGGATGACGGTGGCATTGGGCTGTTGCTGTTCTCG
GGTTCTCGATTGGTCAGCGGCAGCAGCACGGGGCGGCTGCGCCTGTGGGCCGTGGGGGCTGTGTCGGAGCTGAGGTGCAAGGGCTCAGGC
GCCAGATTTGAATTTTTTGTTCCCATGGAAGAAGTAAAGAAGAGGTCACTAGATGTTGCAGTGAAAAATAGTAGGCCACTTGGCTCACAC
AGAAGAAAGGAGTTAGGAAAAGTACTGATTGACTTATCAAAAGAAGATCTGATTAAGGGCTTTTCACAATGGTATGAGCTGACTCCAAAT
GGACAGCCCAGAAGCTGATGATGAGAATTCTTATCACTCACCTTTATATTAAAATGTATATATATGTATATATTTTTTCCTTTGGATCAC
TTACATCCAATATATGTATATTTTGTCATTTAAATCAGAACAACCACTTGAAATTATATACATACAATTCTTGTGTGGAATTTAACTCCA
TGACTGAATAGCATAAGGAAGAGGTTATTTAAAAGCAAGAACTACTTTTTTTGGTTGGATTTTTTTGTTCAAGTCCAGAAAGAAATGTTA
TATTTGTGCCTACTAAATTATCCAAACCTCAGTGTTTATATACTTAAACAAGTGCCACTTTTTAGTAGGTAATTATATACCATCTGATTT
AGGACTTACCTGAATGTATGTACCAGAAAGTGTCCTGCCTCTGGCATAGGGGCTGGGGGAGGTCTGTTTCTGGAGCCACTACCAGCATTC
CTGGGCAGTGACTGGCCAAAGGGAAGTCACTTTTTTATGGAAATAGAAAGTGACCCAACTCAAAACTGCCAAGAGCTAACACTGCCAAAG
CCCTTCTGGCTGCCACCTGTGGTACTTGTATGCCTGGATATTTGTTCTTTTATTTGACCTGGAGCTAAAAATGTATTTCCCTACTGGCAA
AAATGTTATACTGATATACTTAAATACCTTGAGTTAAATACTCTTGTGTAGTCTAAGGGCCAAACTCCAGCGTGTAGCATTATTTCCATA
GGAAAATGCAAACCAAGTTCCAAGCCCAGGTCTATGTCTGACTCTCATAGCAAAGCACTGGAGACTGCTGAAGAGTGTCACCATCAGAGA
AAAGGAAGCTTTCAGATAAGTTTAGGCTATTCAACTTTTCTAAAGAGATGGTTGGTTCACCTAAATAACATGTTAAAAGCAAAGTATTAA
ATTATATGCTTAAACAAGCGCCTCTTTTACATTTCAGACTTTACAAGACCAAATATACTTCTCATCCCCTCCAACATTCCTGGACCTCCT
CTTCTCTCTTACCAACACCAACACTACCTGCCGTCAGTTTTCTGTCTCTGCCTCTGCCTTCACTGCCACTTTTCTGAAGCAGGGCAACAT
TCGAGAACAAAGTTTTGTCATGTTACTCTTATTCCAGTTTCCTGCCATCTGATTCACATGCAGATGTTCTATTCCAGAGTAGTCCAAATA
CTATGCTCTGCTGACTCAAGTCATGTCTCAAACCTATTTCCTCTATTAAGTAAGTCAGTCAATCCATAGTGAAATGGACTCTTCCTACCG
CCTGTAGCATTTACTGTTGATACTGAGTATTTTCCATTTTAATAGTTCCCAGCCTTTATAACACTAAGTTTTAAGAAATGTTGATTAGGC
ATCTGCTAAGGTTACATGCTAAGCAGCTACTTATATTGTATTTGGTATTTAATTTTGTTTATTCTCCAGTTGAACAGTAGGGAACAATTC
AAGCTACTTGAATTGTTTTTCACCCTCACCATCCAAGACCGTGTTAAGTACATAGAAGATGCATGGTGAAATTCGTTTCTGCTGAGGTTT

>99133_99133_1_WDR90-ESYT3_WDR90_chr16_712331_ENST00000293879_ESYT3_chr3_138195065_ENST00000389567_length(amino acids)=1445AA_BP=1381
MARAWQHPFLNVFRHFRVDEWKRSAKQGDVAVVTDKTLKGAVYRIRGSVSAANYIQLPKSSTQSLGLTGRYLYVLFRPLPSKHFVIHLDV
SSKDNQVIRVSFSNLFKEFKSTATWLQFPLVLEARTPQRDLVGLAPSGARWTCLQLDLQDVLLVYLNRCYGHLKSIRLCASLLVRNLYTS
DLCFEPAISGAQWAKLPVTPMPREMAFPVPKGESWHDRYIHVRFPSESLKVPSKPIEKSCSPPEAVLLGPGPQPLPCPVASSKPVRFSVS
PVVQTPSPTASGRAALAPRPFPEVSLSQERSDASNADGPGFHSLEPWAQLEASDIHTAAAGTHVLTHESAEVPVARTGSCEGFLPDPVLR
LKGVIGFGGHGTRQALWTPDGAAVVYPCHAVIVVLLVDTGEQRFFLGHTDKVSALALDGSSSLLASAQARAPSVMRLWDFQTGRCLCLFR
SPMHVVCSLSFSDSGALLCGVGKDHHGRTMVVAWGTGQVGLGGEVVVLAKAHTDFDVQAFRVTFFDETRMASCGQGSVRLWRLRGGVLRS
CPVDLGEHHALQFTDLAFKQARDGCPEPSAAMLFVCSRSGHILEIDCQRMVVRHARRLLPTRTPGGPHPQKQTFSSGPGIAISSLSVSPA
MCAVGSEDGFLRLWPLDFSSVLLEAEHEGPVSSVCVSPDGLRVLSATSSGHLGFLDTLSRVYHMLARSHTAPVLALAMEQRRGQLATVSQ
DRTVRIWDLATLQQLYDFTSSEDAPCAVTFHPTRPTFFCGFSSGAVRSFSLEAAEVLVEHTCHRGAVTGLTATPDGRLLFSSCSQGSLAQ
YSCADPQWHVLRVAADMVCPDAPASPSALAVSRDGRLLAFVGPSRCTVTVMGSASLDELLRVDIGTLDLASSRLDSAMAVCFGPAALGHL
LVSTSSNRVVVLDAVSGRIIRELPGVHPEPCPSLTLSEDARFLLIAAGRTIKVWDYATQASPGPQVYIGHSEPVQAVAFSPDQQQVLSAG
DAVFLWDVLAPTESDQSFPGAPPACKTGPGAGPLEDAASRASELPRQQVPKPCQASPPRLGVCARPPEGGDGARDTRNSGAPRTTYLASC
KAFTPARVSCSPHSAKGTCPPPASGGWLRLKAVVGYSGNGRANMVWRPDTGFFAYTCGRLVVVEDLHSGAQQHWSGHSAEISTLALSHSA
QVLASASGRSSTTAHCQIRVWDVSGGLCQHLIFPHSTTVLALAFSPDDRLLVTLGDHDGRTLALWGTATYDLVSSTRLPEPVHGVAFNPW
DAGELTCVGQGTVTFWLLQQRGADISLQVRREPVPEAVGAGELTSLCYGAPPLLYCGTSSGQVCVWDTRAGRCFLSWEADDGGIGLLLFS
GSRLVSGSSTGRLRLWAVGAVSELRCKGSGARFEFFVPMEEVKKRSLDVAVKNSRPLGSHRRKELGKVLIDLSKEDLIKGFSQWYELTPN

--------------------------------------------------------------
>99133_99133_2_WDR90-ESYT3_WDR90_chr16_712331_ENST00000549091_ESYT3_chr3_138195065_ENST00000389567_length(transcript)=5990nt_BP=4237nt
CACCGTTGCCAGGCAGCCGTTGCCTGGCGTCGCGGGGCGTACTCTGCGCTGGGCGCGCGGAGGCCTAGGCGGGAAGCTCGAGCGGCGGCG
CCATGGCCCGAGCGTGGCAGCACCCGTTCCTCAACGTCTTCAGACACTTCCGGGTGGACGAGTGGAAGCGCTCCGCCAAGCAGGGGGACG
TGGCCGTGGTCACGGACAAGACCCTGAAGGGCGCCGTGTATCGCATTCGGGGCTCAGTCTCTGCCGCCAACTACATCCAGCTCCCTAAGA
GCAGCACCCAGTCTCTGGGGCTGACGGGACGATACCTGTATGTGCTCTTTCGGCCCCTGCCCAGCAAGCACTTCGTCATCCACCTCGATG
TGTCCTCCAAGGACAACCAAGTCATCCGTGTGTCTTTCTCCAACCTCTTCAAGGAGTTTAAGTCTACGGCCACGTGGCTCCAGTTTCCCT
TGGTCCTGGAGGCCAGGACACCTCAGAGAGATCTGGTGGGTTTGGCCCCCTCCGGAGCCCGCTGGACCTGCCTGCAGCTCGATCTGCAGG
ACGTTCTCCTGGTCTACCTGAACCGGTGCTACGGCCATCTCAAGAGCATCAGGCTGTGCGCCAGCCTGCTGGTCAGGAACCTGTACACCA
GTGACCTGTGCTTTGAGCCTGCCATCTCTGGGGCCCAGTGGGCAAAGCTGCCCGTGACTCCTATGCCTCGGGAAATGGCATTCCCTGTGC
CCAAGGGAGAGAGCTGGCATGACCGCTACATCCACGTCCGGTTTCCAAGTGAGAGCTTGAAAGTGCCTTCCAAGCCGATTGAGAAGAGCT
GTTCCCCTCCTGAGGCAGTCCTCCTGGGGCCGGGGCCACAGCCTCTCCCTTGCCCGGTGGCCTCCAGCAAACCTGTGCGGTTCAGTGTGT
CTCCAGTGGTCCAGACGCCCAGCCCCACAGCCTCCGGCCGGGCCGCCTTGGCACCCAGGCCCTTCCCGGAGGTCAGCCTGTCCCAAGAGC
GCTCAGACGCCTCCAACGCGGATGGCCCCGGTTTCCATAGCCTTGAGCCCTGGGCCCAGCTGGAGGCCTCTGACATCCACACGGCTGCTG
CCGGCACCCACGTGTTGACTCACGAGTCGGCTGAGGTGCCCGTGGCCCGCACCGGCTCCTGCGAAGGCTTCCTCCCAGACCCAGTCCTGA
GGCTCAAGGGCGTCATCGGCTTTGGGGGCCACGGCACCAGACAGGCCCTGTGGACCCCAGACGGGGCGGCTGTCGTGTACCCCTGCCATG
CGGTCATCGTCGTCCTGCTCGTGGACACGGGGGAGCAGCGCTTCTTCCTTGGCCACACAGACAAGGTCTCCGCCCTGGCGCTGGATGGCA
GCAGCTCACTATTGGCCTCGGCCCAGGCAAGGGCCCCTAGTGTGATGCGGCTCTGGGACTTCCAGACCGGGCGGTGCTTGTGCCTGTTCC
GGAGCCCAATGCACGTTGTCTGCTCTCTCAGCTTCTCTGACAGCGGGGCCCTTCTCTGCGGGGTTGGCAAGGACCACCACGGGAGGACGA
TGGTGGTGGCCTGGGGCACCGGCCAGGTGGGCCTCGGTGGCGAGGTGGTCGTTCTGGCAAAGGCGCACACTGACTTTGACGTCCAGGCCT
TCCGGGTCACCTTTTTTGATGAAACCAGGATGGCGTCGTGCGGGCAGGGCAGTGTGCGGCTCTGGCGGCTGCGTGGCGGGGTGCTGCGTT
CCTGCCCCGTGGACTTAGGGGAGCACCACGCGCTGCAGTTCACCGACCTGGCCTTCAAGCAGGCCCGGGACGGCTGCCCGGAGCCCTCGG
CTGCCATGCTCTTCGTGTGCAGCCGCAGTGGCCACATCTTGGAGATTGACTGTCAGCGCATGGTCGTGCGGCATGCCCGCCGCCTGCTCC
CCACACGGACTCCAGGCGGTCCCCACCCACAGAAGCAGACCTTCAGCTCAGGCCCCGGCATTGCCATCAGCAGCCTCAGCGTCTCCCCGG
CCATGTGTGCTGTGGGCTCTGAGGACGGCTTCTTGCGGCTCTGGCCCCTGGACTTCTCCTCGGTGCTCCTGGAGGCAGAGCACGAGGGCC
CCGTCAGCTCAGTCTGTGTCAGCCCCGATGGCCTCCGTGTGCTGTCTGCCACCTCCTCGGGCCACCTGGGCTTCCTGGACACGCTGTCCC
GGGTGTACCACATGCTGGCTCGCTCCCACACCGCCCCGGTGTTGGCCCTCGCCATGGAGCAGAGGCGGGGACAGCTGGCCACCGTGTCCC
AGGACCGTACCGTCCGCATCTGGGACCTGGCCACCCTGCAGCAGCTATACGACTTCACATCATCAGAGGACGCCCCGTGCGCTGTCACCT
TCCACCCCACAAGGCCAACCTTTTTCTGTGGCTTTAGCAGTGGGGCCGTGCGCTCCTTCAGCCTGGAGGCCGCTGAGGTCCTGGTGGAAC
ACACGTGCCACCGAGGAGCTGTCACCGGCCTGACCGCCACCCCTGACGGCCGCCTGCTCTTCAGCTCCTGCTCCCAGGGCTCCCTGGCCC
AGTACAGCTGTGCGGACCCCCAGTGGCATGTCCTCCGAGTGGCAGCGGACATGGTATGCCCGGATGCCCCCGCGAGCCCCAGCGCCCTGG
CAGTCAGCAGGGATGGCCGCCTGCTGGCCTTTGTGGGACCCTCCAGGTGCACAGTGACAGTCATGGGCTCGGCCTCCCTTGATGAGCTGC
TGCGAGTTGACATCGGCACTCTGGACCTGGCCAGCAGCCGCCTGGACTCAGCCATGGCTGTGTGCTTTGGCCCTGCAGCTCTGGGCCACC
TGCTGGTGTCCACCTCGTCCAACAGAGTCGTGGTGCTGGATGCTGTGTCGGGCCGCATCATCCGGGAGCTGCCCGGTGTCCACCCTGAGC
CCTGCCCCTCCTTGACGCTCAGTGAGGACGCCCGCTTCCTGCTGATTGCCGCCGGCCGGACCATCAAGGTGTGGGACTACGCCACACAGG
CCAGCCCAGGCCCCCAGGTGTACATCGGCCACTCGGAACCCGTGCAGGCTGTGGCCTTCTCTCCTGACCAGCAGCAGGTCCTCAGCGCAG
GGGACGCCGTCTTCCTCTGGGATGTCCTGGCCCCTACTGAGAGCGACCAAAGCTTCCCCGGGGCCCCCCCAGCCTGCAAGACAGGCCCGG
GCGCAGGACCGCTGGAGGACGCAGCGTCCAGGGCCAGCGAGCTCCCCCGGCAGCAGGTCCCCAAGCCATGTCAGGCATCTCCACCACGGC
TGGGCGTCTGTGCCAGGCCTCCCGAAGGTGGCGATGGCGCCAGGGACACCAGGAATTCGGGGGCCCCACGCACCACCTACCTGGCTTCCT
GCAAGGCCTTCACGCCTGCCAGGGTCAGCTGCAGCCCCCACTCTGCCAAGGGCACTTGCCCGCCTCCCGCCAGCGGTGGGTGGCTGCGTC
TGAAGGCTGTCGTCGGTTACAGCGGGAATGGGCGGGCCAACATGGTCTGGAGGCCGGACACAGGCTTCTTTGCCTACACGTGCGGCCGCC
TGGTGGTGGTGGAGGACCTGCACTCTGGCGCCCAGCAGCACTGGTCCGGCCACTCTGCGGAGATCTCCACGCTGGCCCTCAGCCACAGTG
CCCAGGTCCTGGCCTCTGCCTCGGGCCGAAGCAGCACGACCGCCCATTGTCAGATCCGCGTCTGGGACGTGTCTGGCGGCCTCTGCCAGC
ATCTCATTTTCCCCCATAGCACCACCGTGCTGGCCCTGGCCTTCTCACCAGATGACAGGCTTCTTGTCACACTGGGGGACCACGATGGCC
GCACCCTCGCCCTGTGGGGCACGGCCACCTATGACCTCGTGTCCTCCACCCGCCTCCCGGAGCCGGTGCATGGTGTGGCCTTCAACCCCT
GGGACGCCGGCGAGCTCACCTGTGTGGGCCAGGGCACTGTCACCTTCTGGCTCCTTCAGCAGCGTGGGGCAGACATCAGCCTTCAGGTGC
GTCGAGAGCCAGTCCCAGAGGCAGTGGGGGCTGGAGAGCTGACCTCGCTCTGCTACGGGGCACCTCCCCTGCTCTATTGTGGCACCAGCT
CTGGCCAGGTCTGTGTCTGGGACACGCGTGCCGGCCGCTGCTTCTTGTCCTGGGAGGCGGATGACGGTGGCATTGGGCTGTTGCTGTTCT
CGGGTTCTCGATTGGTCAGCGGCAGCAGCACGGGGCGGCTGCGCCTGTGGGCCGTGGGGGCTGTGTCGGAGCTGAGGTGCAAGGGCTCAG
GCGCCAGATTTGAATTTTTTGTTCCCATGGAAGAAGTAAAGAAGAGGTCACTAGATGTTGCAGTGAAAAATAGTAGGCCACTTGGCTCAC
ACAGAAGAAAGGAGTTAGGAAAAGTACTGATTGACTTATCAAAAGAAGATCTGATTAAGGGCTTTTCACAATGGTATGAGCTGACTCCAA
ATGGACAGCCCAGAAGCTGATGATGAGAATTCTTATCACTCACCTTTATATTAAAATGTATATATATGTATATATTTTTTCCTTTGGATC
ACTTACATCCAATATATGTATATTTTGTCATTTAAATCAGAACAACCACTTGAAATTATATACATACAATTCTTGTGTGGAATTTAACTC
CATGACTGAATAGCATAAGGAAGAGGTTATTTAAAAGCAAGAACTACTTTTTTTGGTTGGATTTTTTTGTTCAAGTCCAGAAAGAAATGT
TATATTTGTGCCTACTAAATTATCCAAACCTCAGTGTTTATATACTTAAACAAGTGCCACTTTTTAGTAGGTAATTATATACCATCTGAT
TTAGGACTTACCTGAATGTATGTACCAGAAAGTGTCCTGCCTCTGGCATAGGGGCTGGGGGAGGTCTGTTTCTGGAGCCACTACCAGCAT
TCCTGGGCAGTGACTGGCCAAAGGGAAGTCACTTTTTTATGGAAATAGAAAGTGACCCAACTCAAAACTGCCAAGAGCTAACACTGCCAA
AGCCCTTCTGGCTGCCACCTGTGGTACTTGTATGCCTGGATATTTGTTCTTTTATTTGACCTGGAGCTAAAAATGTATTTCCCTACTGGC
AAAAATGTTATACTGATATACTTAAATACCTTGAGTTAAATACTCTTGTGTAGTCTAAGGGCCAAACTCCAGCGTGTAGCATTATTTCCA
TAGGAAAATGCAAACCAAGTTCCAAGCCCAGGTCTATGTCTGACTCTCATAGCAAAGCACTGGAGACTGCTGAAGAGTGTCACCATCAGA
GAAAAGGAAGCTTTCAGATAAGTTTAGGCTATTCAACTTTTCTAAAGAGATGGTTGGTTCACCTAAATAACATGTTAAAAGCAAAGTATT
AAATTATATGCTTAAACAAGCGCCTCTTTTACATTTCAGACTTTACAAGACCAAATATACTTCTCATCCCCTCCAACATTCCTGGACCTC
CTCTTCTCTCTTACCAACACCAACACTACCTGCCGTCAGTTTTCTGTCTCTGCCTCTGCCTTCACTGCCACTTTTCTGAAGCAGGGCAAC
ATTCGAGAACAAAGTTTTGTCATGTTACTCTTATTCCAGTTTCCTGCCATCTGATTCACATGCAGATGTTCTATTCCAGAGTAGTCCAAA
TACTATGCTCTGCTGACTCAAGTCATGTCTCAAACCTATTTCCTCTATTAAGTAAGTCAGTCAATCCATAGTGAAATGGACTCTTCCTAC
CGCCTGTAGCATTTACTGTTGATACTGAGTATTTTCCATTTTAATAGTTCCCAGCCTTTATAACACTAAGTTTTAAGAAATGTTGATTAG
GCATCTGCTAAGGTTACATGCTAAGCAGCTACTTATATTGTATTTGGTATTTAATTTTGTTTATTCTCCAGTTGAACAGTAGGGAACAAT
TCAAGCTACTTGAATTGTTTTTCACCCTCACCATCCAAGACCGTGTTAAGTACATAGAAGATGCATGGTGAAATTCGTTTCTGCTGAGGT

>99133_99133_2_WDR90-ESYT3_WDR90_chr16_712331_ENST00000549091_ESYT3_chr3_138195065_ENST00000389567_length(amino acids)=1445AA_BP=1381
MARAWQHPFLNVFRHFRVDEWKRSAKQGDVAVVTDKTLKGAVYRIRGSVSAANYIQLPKSSTQSLGLTGRYLYVLFRPLPSKHFVIHLDV
SSKDNQVIRVSFSNLFKEFKSTATWLQFPLVLEARTPQRDLVGLAPSGARWTCLQLDLQDVLLVYLNRCYGHLKSIRLCASLLVRNLYTS
DLCFEPAISGAQWAKLPVTPMPREMAFPVPKGESWHDRYIHVRFPSESLKVPSKPIEKSCSPPEAVLLGPGPQPLPCPVASSKPVRFSVS
PVVQTPSPTASGRAALAPRPFPEVSLSQERSDASNADGPGFHSLEPWAQLEASDIHTAAAGTHVLTHESAEVPVARTGSCEGFLPDPVLR
LKGVIGFGGHGTRQALWTPDGAAVVYPCHAVIVVLLVDTGEQRFFLGHTDKVSALALDGSSSLLASAQARAPSVMRLWDFQTGRCLCLFR
SPMHVVCSLSFSDSGALLCGVGKDHHGRTMVVAWGTGQVGLGGEVVVLAKAHTDFDVQAFRVTFFDETRMASCGQGSVRLWRLRGGVLRS
CPVDLGEHHALQFTDLAFKQARDGCPEPSAAMLFVCSRSGHILEIDCQRMVVRHARRLLPTRTPGGPHPQKQTFSSGPGIAISSLSVSPA
MCAVGSEDGFLRLWPLDFSSVLLEAEHEGPVSSVCVSPDGLRVLSATSSGHLGFLDTLSRVYHMLARSHTAPVLALAMEQRRGQLATVSQ
DRTVRIWDLATLQQLYDFTSSEDAPCAVTFHPTRPTFFCGFSSGAVRSFSLEAAEVLVEHTCHRGAVTGLTATPDGRLLFSSCSQGSLAQ
YSCADPQWHVLRVAADMVCPDAPASPSALAVSRDGRLLAFVGPSRCTVTVMGSASLDELLRVDIGTLDLASSRLDSAMAVCFGPAALGHL
LVSTSSNRVVVLDAVSGRIIRELPGVHPEPCPSLTLSEDARFLLIAAGRTIKVWDYATQASPGPQVYIGHSEPVQAVAFSPDQQQVLSAG
DAVFLWDVLAPTESDQSFPGAPPACKTGPGAGPLEDAASRASELPRQQVPKPCQASPPRLGVCARPPEGGDGARDTRNSGAPRTTYLASC
KAFTPARVSCSPHSAKGTCPPPASGGWLRLKAVVGYSGNGRANMVWRPDTGFFAYTCGRLVVVEDLHSGAQQHWSGHSAEISTLALSHSA
QVLASASGRSSTTAHCQIRVWDVSGGLCQHLIFPHSTTVLALAFSPDDRLLVTLGDHDGRTLALWGTATYDLVSSTRLPEPVHGVAFNPW
DAGELTCVGQGTVTFWLLQQRGADISLQVRREPVPEAVGAGELTSLCYGAPPLLYCGTSSGQVCVWDTRAGRCFLSWEADDGGIGLLLFS
GSRLVSGSSTGRLRLWAVGAVSELRCKGSGARFEFFVPMEEVKKRSLDVAVKNSRPLGSHRRKELGKVLIDLSKEDLIKGFSQWYELTPN

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Fusion Gene PPI Analysis for WDR90-ESYT3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for WDR90-ESYT3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for WDR90-ESYT3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource