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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:WHSC1-GSDMB (FusionGDB2 ID:99189)

Fusion Gene Summary for WHSC1-GSDMB

check button Fusion gene summary
Fusion gene informationFusion gene name: WHSC1-GSDMB
Fusion gene ID: 99189
HgeneTgene
Gene symbol

WHSC1

GSDMB

Gene ID

7468

55876

Gene namenuclear receptor binding SET domain protein 2gasdermin B
SynonymsKMT3F|KMT3G|MMSET|REIIBP|TRX5|WHS|WHSC1GSDMB-1|GSDML|PP4052|PRO2521
Cytomap

4p16.3

17q21.1

Type of geneprotein-codingprotein-coding
Descriptionhistone-lysine N-methyltransferase NSD2IL5 promoter REII region-binding proteinWolf-Hirschhorn syndrome candidate 1multiple myeloma SET domain containing protein type IIInuclear SET domain-containing protein 2probable histone-lysine N-methyltransferagasdermin-Bgasdermin-like proteingasderminB-1
Modification date2020032920200313
UniProtAcc.

Q8TAX9

Ensembl transtripts involved in fusion geneENST00000482415, ENST00000382888, 
ENST00000382891, ENST00000382892, 
ENST00000382895, ENST00000508803, 
ENST00000398261, ENST00000420906, 
ENST00000436793, ENST00000503128, 
ENST00000514045, 		ENST00000309481, 
ENST00000360317, ENST00000394175, 
ENST00000394179, ENST00000418519, 
ENST00000520542, 
Fusion gene scores* DoF score22 X 18 X 13=514812 X 13 X 9=1404
# samples 2715
** MAII scorelog2(27/5148*10)=-4.25298074116987
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(15/1404*10)=-3.22650852980868
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: WHSC1 [Title/Abstract] AND GSDMB [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointWHSC1(1957915)-GSDMB(38068750), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across WHSC1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across GSDMB (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUADTCGA-38-4630-01AWHSC1chr4

1957915

-GSDMBchr17

38068750

-
ChimerDB4LUADTCGA-38-4630-01AWHSC1chr4

1957915

+GSDMBchr17

38068750

-
ChimerDB4LUADTCGA-38-4630WHSC1chr4

1957915

+GSDMBchr17

38068750

-


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Fusion Gene ORF analysis for WHSC1-GSDMB

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000482415ENST00000309481WHSC1chr4

1957915

+GSDMBchr17

38068750

-
3UTR-3CDSENST00000482415ENST00000360317WHSC1chr4

1957915

+GSDMBchr17

38068750

-
3UTR-3CDSENST00000482415ENST00000394175WHSC1chr4

1957915

+GSDMBchr17

38068750

-
3UTR-3CDSENST00000482415ENST00000394179WHSC1chr4

1957915

+GSDMBchr17

38068750

-
3UTR-3CDSENST00000482415ENST00000418519WHSC1chr4

1957915

+GSDMBchr17

38068750

-
3UTR-3CDSENST00000482415ENST00000520542WHSC1chr4

1957915

+GSDMBchr17

38068750

-
In-frameENST00000382888ENST00000309481WHSC1chr4

1957915

+GSDMBchr17

38068750

-
In-frameENST00000382888ENST00000360317WHSC1chr4

1957915

+GSDMBchr17

38068750

-
In-frameENST00000382888ENST00000394175WHSC1chr4

1957915

+GSDMBchr17

38068750

-
In-frameENST00000382888ENST00000394179WHSC1chr4

1957915

+GSDMBchr17

38068750

-
In-frameENST00000382888ENST00000418519WHSC1chr4

1957915

+GSDMBchr17

38068750

-
In-frameENST00000382888ENST00000520542WHSC1chr4

1957915

+GSDMBchr17

38068750

-
In-frameENST00000382891ENST00000309481WHSC1chr4

1957915

+GSDMBchr17

38068750

-
In-frameENST00000382891ENST00000360317WHSC1chr4

1957915

+GSDMBchr17

38068750

-
In-frameENST00000382891ENST00000394175WHSC1chr4

1957915

+GSDMBchr17

38068750

-
In-frameENST00000382891ENST00000394179WHSC1chr4

1957915

+GSDMBchr17

38068750

-
In-frameENST00000382891ENST00000418519WHSC1chr4

1957915

+GSDMBchr17

38068750

-
In-frameENST00000382891ENST00000520542WHSC1chr4

1957915

+GSDMBchr17

38068750

-
In-frameENST00000382892ENST00000309481WHSC1chr4

1957915

+GSDMBchr17

38068750

-
In-frameENST00000382892ENST00000360317WHSC1chr4

1957915

+GSDMBchr17

38068750

-
In-frameENST00000382892ENST00000394175WHSC1chr4

1957915

+GSDMBchr17

38068750

-
In-frameENST00000382892ENST00000394179WHSC1chr4

1957915

+GSDMBchr17

38068750

-
In-frameENST00000382892ENST00000418519WHSC1chr4

1957915

+GSDMBchr17

38068750

-
In-frameENST00000382892ENST00000520542WHSC1chr4

1957915

+GSDMBchr17

38068750

-
In-frameENST00000382895ENST00000309481WHSC1chr4

1957915

+GSDMBchr17

38068750

-
In-frameENST00000382895ENST00000360317WHSC1chr4

1957915

+GSDMBchr17

38068750

-
In-frameENST00000382895ENST00000394175WHSC1chr4

1957915

+GSDMBchr17

38068750

-
In-frameENST00000382895ENST00000394179WHSC1chr4

1957915

+GSDMBchr17

38068750

-
In-frameENST00000382895ENST00000418519WHSC1chr4

1957915

+GSDMBchr17

38068750

-
In-frameENST00000382895ENST00000520542WHSC1chr4

1957915

+GSDMBchr17

38068750

-
In-frameENST00000508803ENST00000309481WHSC1chr4

1957915

+GSDMBchr17

38068750

-
In-frameENST00000508803ENST00000360317WHSC1chr4

1957915

+GSDMBchr17

38068750

-
In-frameENST00000508803ENST00000394175WHSC1chr4

1957915

+GSDMBchr17

38068750

-
In-frameENST00000508803ENST00000394179WHSC1chr4

1957915

+GSDMBchr17

38068750

-
In-frameENST00000508803ENST00000418519WHSC1chr4

1957915

+GSDMBchr17

38068750

-
In-frameENST00000508803ENST00000520542WHSC1chr4

1957915

+GSDMBchr17

38068750

-
intron-3CDSENST00000398261ENST00000309481WHSC1chr4

1957915

+GSDMBchr17

38068750

-
intron-3CDSENST00000398261ENST00000360317WHSC1chr4

1957915

+GSDMBchr17

38068750

-
intron-3CDSENST00000398261ENST00000394175WHSC1chr4

1957915

+GSDMBchr17

38068750

-
intron-3CDSENST00000398261ENST00000394179WHSC1chr4

1957915

+GSDMBchr17

38068750

-
intron-3CDSENST00000398261ENST00000418519WHSC1chr4

1957915

+GSDMBchr17

38068750

-
intron-3CDSENST00000398261ENST00000520542WHSC1chr4

1957915

+GSDMBchr17

38068750

-
intron-3CDSENST00000420906ENST00000309481WHSC1chr4

1957915

+GSDMBchr17

38068750

-
intron-3CDSENST00000420906ENST00000360317WHSC1chr4

1957915

+GSDMBchr17

38068750

-
intron-3CDSENST00000420906ENST00000394175WHSC1chr4

1957915

+GSDMBchr17

38068750

-
intron-3CDSENST00000420906ENST00000394179WHSC1chr4

1957915

+GSDMBchr17

38068750

-
intron-3CDSENST00000420906ENST00000418519WHSC1chr4

1957915

+GSDMBchr17

38068750

-
intron-3CDSENST00000420906ENST00000520542WHSC1chr4

1957915

+GSDMBchr17

38068750

-
intron-3CDSENST00000436793ENST00000309481WHSC1chr4

1957915

+GSDMBchr17

38068750

-
intron-3CDSENST00000436793ENST00000360317WHSC1chr4

1957915

+GSDMBchr17

38068750

-
intron-3CDSENST00000436793ENST00000394175WHSC1chr4

1957915

+GSDMBchr17

38068750

-
intron-3CDSENST00000436793ENST00000394179WHSC1chr4

1957915

+GSDMBchr17

38068750

-
intron-3CDSENST00000436793ENST00000418519WHSC1chr4

1957915

+GSDMBchr17

38068750

-
intron-3CDSENST00000436793ENST00000520542WHSC1chr4

1957915

+GSDMBchr17

38068750

-
intron-3CDSENST00000503128ENST00000309481WHSC1chr4

1957915

+GSDMBchr17

38068750

-
intron-3CDSENST00000503128ENST00000360317WHSC1chr4

1957915

+GSDMBchr17

38068750

-
intron-3CDSENST00000503128ENST00000394175WHSC1chr4

1957915

+GSDMBchr17

38068750

-
intron-3CDSENST00000503128ENST00000394179WHSC1chr4

1957915

+GSDMBchr17

38068750

-
intron-3CDSENST00000503128ENST00000418519WHSC1chr4

1957915

+GSDMBchr17

38068750

-
intron-3CDSENST00000503128ENST00000520542WHSC1chr4

1957915

+GSDMBchr17

38068750

-
intron-3CDSENST00000514045ENST00000309481WHSC1chr4

1957915

+GSDMBchr17

38068750

-
intron-3CDSENST00000514045ENST00000360317WHSC1chr4

1957915

+GSDMBchr17

38068750

-
intron-3CDSENST00000514045ENST00000394175WHSC1chr4

1957915

+GSDMBchr17

38068750

-
intron-3CDSENST00000514045ENST00000394179WHSC1chr4

1957915

+GSDMBchr17

38068750

-
intron-3CDSENST00000514045ENST00000418519WHSC1chr4

1957915

+GSDMBchr17

38068750

-
intron-3CDSENST00000514045ENST00000520542WHSC1chr4

1957915

+GSDMBchr17

38068750

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000508803WHSC1chr41957915+ENST00000360317GSDMBchr1738068750-4262302913940441301
ENST00000508803WHSC1chr41957915+ENST00000394175GSDMBchr1738068750-4196302913939781279
ENST00000508803WHSC1chr41957915+ENST00000309481GSDMBchr1738068750-4223302913940051288
ENST00000508803WHSC1chr41957915+ENST00000520542GSDMBchr1738068750-4233302913940171292
ENST00000508803WHSC1chr41957915+ENST00000418519GSDMBchr1738068750-4260302913940441301
ENST00000508803WHSC1chr41957915+ENST00000394179GSDMBchr1738068750-4245302913940291296
ENST00000382892WHSC1chr41957915+ENST00000360317GSDMBchr1738068750-4428319530542101301
ENST00000382892WHSC1chr41957915+ENST00000394175GSDMBchr1738068750-4362319530541441279
ENST00000382892WHSC1chr41957915+ENST00000309481GSDMBchr1738068750-4389319530541711288
ENST00000382892WHSC1chr41957915+ENST00000520542GSDMBchr1738068750-4399319530541831292
ENST00000382892WHSC1chr41957915+ENST00000418519GSDMBchr1738068750-4426319530542101301
ENST00000382892WHSC1chr41957915+ENST00000394179GSDMBchr1738068750-4411319530541951296
ENST00000382891WHSC1chr41957915+ENST00000360317GSDMBchr1738068750-4253302013040351301
ENST00000382891WHSC1chr41957915+ENST00000394175GSDMBchr1738068750-4187302013039691279
ENST00000382891WHSC1chr41957915+ENST00000309481GSDMBchr1738068750-4214302013039961288
ENST00000382891WHSC1chr41957915+ENST00000520542GSDMBchr1738068750-4224302013040081292
ENST00000382891WHSC1chr41957915+ENST00000418519GSDMBchr1738068750-4251302013040351301
ENST00000382891WHSC1chr41957915+ENST00000394179GSDMBchr1738068750-4236302013040201296
ENST00000382895WHSC1chr41957915+ENST00000360317GSDMBchr1738068750-4545331242243271301
ENST00000382895WHSC1chr41957915+ENST00000394175GSDMBchr1738068750-4479331242242611279
ENST00000382895WHSC1chr41957915+ENST00000309481GSDMBchr1738068750-4506331242242881288
ENST00000382895WHSC1chr41957915+ENST00000520542GSDMBchr1738068750-4516331242243001292
ENST00000382895WHSC1chr41957915+ENST00000418519GSDMBchr1738068750-4543331242243271301
ENST00000382895WHSC1chr41957915+ENST00000394179GSDMBchr1738068750-4528331242243121296
ENST00000382888WHSC1chr41957915+ENST00000360317GSDMBchr1738068750-267614435152458647
ENST00000382888WHSC1chr41957915+ENST00000394175GSDMBchr1738068750-261014435152392625
ENST00000382888WHSC1chr41957915+ENST00000309481GSDMBchr1738068750-263714435152419634
ENST00000382888WHSC1chr41957915+ENST00000520542GSDMBchr1738068750-264714435152431638
ENST00000382888WHSC1chr41957915+ENST00000418519GSDMBchr1738068750-267414435152458647
ENST00000382888WHSC1chr41957915+ENST00000394179GSDMBchr1738068750-265914435152443642

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000508803ENST00000360317WHSC1chr41957915+GSDMBchr1738068750-0.0008487010.99915135
ENST00000508803ENST00000394175WHSC1chr41957915+GSDMBchr1738068750-0.0007283990.9992716
ENST00000508803ENST00000309481WHSC1chr41957915+GSDMBchr1738068750-0.000777890.99922216
ENST00000508803ENST00000520542WHSC1chr41957915+GSDMBchr1738068750-0.0006528160.99934715
ENST00000508803ENST00000418519WHSC1chr41957915+GSDMBchr1738068750-0.0008599610.99914
ENST00000508803ENST00000394179WHSC1chr41957915+GSDMBchr1738068750-0.0004553140.9995447
ENST00000382892ENST00000360317WHSC1chr41957915+GSDMBchr1738068750-0.0010166290.9989833
ENST00000382892ENST00000394175WHSC1chr41957915+GSDMBchr1738068750-0.0008850690.99911493
ENST00000382892ENST00000309481WHSC1chr41957915+GSDMBchr1738068750-0.0009487330.9990513
ENST00000382892ENST00000520542WHSC1chr41957915+GSDMBchr1738068750-0.000799810.99920017
ENST00000382892ENST00000418519WHSC1chr41957915+GSDMBchr1738068750-0.001030870.9989692
ENST00000382892ENST00000394179WHSC1chr41957915+GSDMBchr1738068750-0.0005588390.9994412
ENST00000382891ENST00000360317WHSC1chr41957915+GSDMBchr1738068750-0.000734550.9992655
ENST00000382891ENST00000394175WHSC1chr41957915+GSDMBchr1738068750-0.0006276930.9993723
ENST00000382891ENST00000309481WHSC1chr41957915+GSDMBchr1738068750-0.0006733460.9993267
ENST00000382891ENST00000520542WHSC1chr41957915+GSDMBchr1738068750-0.0005618370.9994381
ENST00000382891ENST00000418519WHSC1chr41957915+GSDMBchr1738068750-0.0007440680.99925596
ENST00000382891ENST00000394179WHSC1chr41957915+GSDMBchr1738068750-0.0003934420.99960655
ENST00000382895ENST00000360317WHSC1chr41957915+GSDMBchr1738068750-0.001178650.9988213
ENST00000382895ENST00000394175WHSC1chr41957915+GSDMBchr1738068750-0.0010220890.9989779
ENST00000382895ENST00000309481WHSC1chr41957915+GSDMBchr1738068750-0.0010925510.99890745
ENST00000382895ENST00000520542WHSC1chr41957915+GSDMBchr1738068750-0.0009209640.999079
ENST00000382895ENST00000418519WHSC1chr41957915+GSDMBchr1738068750-0.001194740.9988053
ENST00000382895ENST00000394179WHSC1chr41957915+GSDMBchr1738068750-0.0006433340.9993567
ENST00000382888ENST00000360317WHSC1chr41957915+GSDMBchr1738068750-0.0064909020.9935091
ENST00000382888ENST00000394175WHSC1chr41957915+GSDMBchr1738068750-0.0075225980.9924775
ENST00000382888ENST00000309481WHSC1chr41957915+GSDMBchr1738068750-0.0058570190.99414295
ENST00000382888ENST00000520542WHSC1chr41957915+GSDMBchr1738068750-0.0086513930.9913487
ENST00000382888ENST00000418519WHSC1chr41957915+GSDMBchr1738068750-0.0066357110.99336433
ENST00000382888ENST00000394179WHSC1chr41957915+GSDMBchr1738068750-0.0071345460.99286544

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Fusion Genomic Features for WHSC1-GSDMB


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for WHSC1-GSDMB


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr4:1957915/chr17:38068750)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.GSDMB

Q8TAX9

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: [Gasdermin-B]: Precursor of a pore-forming protein that acts as a downstream mediator of granzyme-mediated cell death (PubMed:32299851). This form constitutes the precursor of the pore-forming protein: upon cleavage, the released N-terminal moiety (Gasdermin-B, N-terminal) binds to membranes and forms pores, triggering pyroptosis (PubMed:32299851). {ECO:0000269|PubMed:32299851}.; FUNCTION: [Gasdermin-B, N-terminal]: Pore-forming protein produced by cleavage by granzyme A (GZMA), which causes membrane permeabilization and pyroptosis in target cells of cytotoxic T and natural killer (NK) cells (PubMed:27281216, PubMed:32299851). Key downstream mediator of granzyme-mediated cell death: (1) granzyme A (GZMA), delivered to target cells from cytotoxic T- and NK-cells, (2) specifically cleaves Gasdermin-B to generate this form (PubMed:32299851). After cleavage, moves to the plasma membrane, homooligomerizes within the membrane and forms pores of 10-15 nanometers (nm) of inner diameter, triggering pyroptosis (PubMed:32299851). Binds to membrane inner leaflet lipids, such as phosphatidylinositol 4-phosphate, phosphatidylinositol 5-phosphate, bisphosphorylated phosphatidylinositols, such as phosphatidylinositol (4,5)-bisphosphate, and more weakly to phosphatidic acid (PubMed:28154144). Also binds sufatide, a component of the apical membrane of epithelial cells (PubMed:28154144). {ECO:0000269|PubMed:27281216, ECO:0000269|PubMed:28154144, ECO:0000269|PubMed:32299851}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneWHSC1chr4:1957915chr17:38068750ENST00000382891+1522453_5219601366.0DNA bindingHMG box
HgeneWHSC1chr4:1957915chr17:38068750ENST00000382892+1623453_5219601366.0DNA bindingHMG box
HgeneWHSC1chr4:1957915chr17:38068750ENST00000382895+1724453_5219601366.0DNA bindingHMG box
HgeneWHSC1chr4:1957915chr17:38068750ENST00000508803+1522453_5219601366.0DNA bindingHMG box
HgeneWHSC1chr4:1957915chr17:38068750ENST00000382888+512222_286308714.0DomainPWWP 1
HgeneWHSC1chr4:1957915chr17:38068750ENST00000382891+1522222_2869601366.0DomainPWWP 1
HgeneWHSC1chr4:1957915chr17:38068750ENST00000382891+1522880_9429601366.0DomainPWWP 2
HgeneWHSC1chr4:1957915chr17:38068750ENST00000382892+1623222_2869601366.0DomainPWWP 1
HgeneWHSC1chr4:1957915chr17:38068750ENST00000382892+1623880_9429601366.0DomainPWWP 2
HgeneWHSC1chr4:1957915chr17:38068750ENST00000382895+1724222_2869601366.0DomainPWWP 1
HgeneWHSC1chr4:1957915chr17:38068750ENST00000382895+1724880_9429601366.0DomainPWWP 2
HgeneWHSC1chr4:1957915chr17:38068750ENST00000508803+1522222_2869601366.0DomainPWWP 1
HgeneWHSC1chr4:1957915chr17:38068750ENST00000508803+1522880_9429601366.0DomainPWWP 2
HgeneWHSC1chr4:1957915chr17:38068750ENST00000382891+1522667_7139601366.0Zinc fingerPHD-type 1
HgeneWHSC1chr4:1957915chr17:38068750ENST00000382891+1522714_7709601366.0Zinc fingerPHD-type 2
HgeneWHSC1chr4:1957915chr17:38068750ENST00000382891+1522831_8759601366.0Zinc fingerPHD-type 3
HgeneWHSC1chr4:1957915chr17:38068750ENST00000382892+1623667_7139601366.0Zinc fingerPHD-type 1
HgeneWHSC1chr4:1957915chr17:38068750ENST00000382892+1623714_7709601366.0Zinc fingerPHD-type 2
HgeneWHSC1chr4:1957915chr17:38068750ENST00000382892+1623831_8759601366.0Zinc fingerPHD-type 3
HgeneWHSC1chr4:1957915chr17:38068750ENST00000382895+1724667_7139601366.0Zinc fingerPHD-type 1
HgeneWHSC1chr4:1957915chr17:38068750ENST00000382895+1724714_7709601366.0Zinc fingerPHD-type 2
HgeneWHSC1chr4:1957915chr17:38068750ENST00000382895+1724831_8759601366.0Zinc fingerPHD-type 3
HgeneWHSC1chr4:1957915chr17:38068750ENST00000508803+1522667_7139601366.0Zinc fingerPHD-type 1
HgeneWHSC1chr4:1957915chr17:38068750ENST00000508803+1522714_7709601366.0Zinc fingerPHD-type 2
HgeneWHSC1chr4:1957915chr17:38068750ENST00000508803+1522831_8759601366.0Zinc fingerPHD-type 3
TgeneGSDMBchr4:1957915chr17:38068750ENST00000309481110243_27178404.0Coiled coilOntology_term=ECO:0000255
TgeneGSDMBchr4:1957915chr17:38068750ENST00000360317010243_27178417.0Coiled coilOntology_term=ECO:0000255
TgeneGSDMBchr4:1957915chr17:38068750ENST0000039417508243_27178395.0Coiled coilOntology_term=ECO:0000255
TgeneGSDMBchr4:1957915chr17:38068750ENST00000394179110243_27178412.0Coiled coilOntology_term=ECO:0000255
TgeneGSDMBchr4:1957915chr17:38068750ENST00000418519111243_27178417.0Coiled coilOntology_term=ECO:0000255
TgeneGSDMBchr4:1957915chr17:38068750ENST00000520542110243_27178408.0Coiled coilOntology_term=ECO:0000255

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneWHSC1chr4:1957915chr17:38068750ENST00000382888+512453_521308714.0DNA bindingHMG box
HgeneWHSC1chr4:1957915chr17:38068750ENST00000398261+19453_5210648.0DNA bindingHMG box
HgeneWHSC1chr4:1957915chr17:38068750ENST00000420906+111453_5210630.0DNA bindingHMG box
HgeneWHSC1chr4:1957915chr17:38068750ENST00000436793+16453_5210274.0DNA bindingHMG box
HgeneWHSC1chr4:1957915chr17:38068750ENST00000503128+110453_5210648.0DNA bindingHMG box
HgeneWHSC1chr4:1957915chr17:38068750ENST00000514045+19453_5210630.0DNA bindingHMG box
HgeneWHSC1chr4:1957915chr17:38068750ENST00000382888+5121011_1061308714.0DomainAWS
HgeneWHSC1chr4:1957915chr17:38068750ENST00000382888+5121063_1180308714.0DomainSET
HgeneWHSC1chr4:1957915chr17:38068750ENST00000382888+5121187_1203308714.0DomainPost-SET
HgeneWHSC1chr4:1957915chr17:38068750ENST00000382888+512880_942308714.0DomainPWWP 2
HgeneWHSC1chr4:1957915chr17:38068750ENST00000382891+15221011_10619601366.0DomainAWS
HgeneWHSC1chr4:1957915chr17:38068750ENST00000382891+15221063_11809601366.0DomainSET
HgeneWHSC1chr4:1957915chr17:38068750ENST00000382891+15221187_12039601366.0DomainPost-SET
HgeneWHSC1chr4:1957915chr17:38068750ENST00000382892+16231011_10619601366.0DomainAWS
HgeneWHSC1chr4:1957915chr17:38068750ENST00000382892+16231063_11809601366.0DomainSET
HgeneWHSC1chr4:1957915chr17:38068750ENST00000382892+16231187_12039601366.0DomainPost-SET
HgeneWHSC1chr4:1957915chr17:38068750ENST00000382895+17241011_10619601366.0DomainAWS
HgeneWHSC1chr4:1957915chr17:38068750ENST00000382895+17241063_11809601366.0DomainSET
HgeneWHSC1chr4:1957915chr17:38068750ENST00000382895+17241187_12039601366.0DomainPost-SET
HgeneWHSC1chr4:1957915chr17:38068750ENST00000398261+191011_10610648.0DomainAWS
HgeneWHSC1chr4:1957915chr17:38068750ENST00000398261+191063_11800648.0DomainSET
HgeneWHSC1chr4:1957915chr17:38068750ENST00000398261+191187_12030648.0DomainPost-SET
HgeneWHSC1chr4:1957915chr17:38068750ENST00000398261+19222_2860648.0DomainPWWP 1
HgeneWHSC1chr4:1957915chr17:38068750ENST00000398261+19880_9420648.0DomainPWWP 2
HgeneWHSC1chr4:1957915chr17:38068750ENST00000420906+1111011_10610630.0DomainAWS
HgeneWHSC1chr4:1957915chr17:38068750ENST00000420906+1111063_11800630.0DomainSET
HgeneWHSC1chr4:1957915chr17:38068750ENST00000420906+1111187_12030630.0DomainPost-SET
HgeneWHSC1chr4:1957915chr17:38068750ENST00000420906+111222_2860630.0DomainPWWP 1
HgeneWHSC1chr4:1957915chr17:38068750ENST00000420906+111880_9420630.0DomainPWWP 2
HgeneWHSC1chr4:1957915chr17:38068750ENST00000436793+161011_10610274.0DomainAWS
HgeneWHSC1chr4:1957915chr17:38068750ENST00000436793+161063_11800274.0DomainSET
HgeneWHSC1chr4:1957915chr17:38068750ENST00000436793+161187_12030274.0DomainPost-SET
HgeneWHSC1chr4:1957915chr17:38068750ENST00000436793+16222_2860274.0DomainPWWP 1
HgeneWHSC1chr4:1957915chr17:38068750ENST00000436793+16880_9420274.0DomainPWWP 2
HgeneWHSC1chr4:1957915chr17:38068750ENST00000503128+1101011_10610648.0DomainAWS
HgeneWHSC1chr4:1957915chr17:38068750ENST00000503128+1101063_11800648.0DomainSET
HgeneWHSC1chr4:1957915chr17:38068750ENST00000503128+1101187_12030648.0DomainPost-SET
HgeneWHSC1chr4:1957915chr17:38068750ENST00000503128+110222_2860648.0DomainPWWP 1
HgeneWHSC1chr4:1957915chr17:38068750ENST00000503128+110880_9420648.0DomainPWWP 2
HgeneWHSC1chr4:1957915chr17:38068750ENST00000508803+15221011_10619601366.0DomainAWS
HgeneWHSC1chr4:1957915chr17:38068750ENST00000508803+15221063_11809601366.0DomainSET
HgeneWHSC1chr4:1957915chr17:38068750ENST00000508803+15221187_12039601366.0DomainPost-SET
HgeneWHSC1chr4:1957915chr17:38068750ENST00000514045+191011_10610630.0DomainAWS
HgeneWHSC1chr4:1957915chr17:38068750ENST00000514045+191063_11800630.0DomainSET
HgeneWHSC1chr4:1957915chr17:38068750ENST00000514045+191187_12030630.0DomainPost-SET
HgeneWHSC1chr4:1957915chr17:38068750ENST00000514045+19222_2860630.0DomainPWWP 1
HgeneWHSC1chr4:1957915chr17:38068750ENST00000514045+19880_9420630.0DomainPWWP 2
HgeneWHSC1chr4:1957915chr17:38068750ENST00000382888+5121115_1118308714.0RegionS-adenosyl-L-methionine binding
HgeneWHSC1chr4:1957915chr17:38068750ENST00000382888+5121141_1142308714.0RegionS-adenosyl-L-methionine binding
HgeneWHSC1chr4:1957915chr17:38068750ENST00000382891+15221115_11189601366.0RegionS-adenosyl-L-methionine binding
HgeneWHSC1chr4:1957915chr17:38068750ENST00000382891+15221141_11429601366.0RegionS-adenosyl-L-methionine binding
HgeneWHSC1chr4:1957915chr17:38068750ENST00000382892+16231115_11189601366.0RegionS-adenosyl-L-methionine binding
HgeneWHSC1chr4:1957915chr17:38068750ENST00000382892+16231141_11429601366.0RegionS-adenosyl-L-methionine binding
HgeneWHSC1chr4:1957915chr17:38068750ENST00000382895+17241115_11189601366.0RegionS-adenosyl-L-methionine binding
HgeneWHSC1chr4:1957915chr17:38068750ENST00000382895+17241141_11429601366.0RegionS-adenosyl-L-methionine binding
HgeneWHSC1chr4:1957915chr17:38068750ENST00000398261+191115_11180648.0RegionS-adenosyl-L-methionine binding
HgeneWHSC1chr4:1957915chr17:38068750ENST00000398261+191141_11420648.0RegionS-adenosyl-L-methionine binding
HgeneWHSC1chr4:1957915chr17:38068750ENST00000420906+1111115_11180630.0RegionS-adenosyl-L-methionine binding
HgeneWHSC1chr4:1957915chr17:38068750ENST00000420906+1111141_11420630.0RegionS-adenosyl-L-methionine binding
HgeneWHSC1chr4:1957915chr17:38068750ENST00000436793+161115_11180274.0RegionS-adenosyl-L-methionine binding
HgeneWHSC1chr4:1957915chr17:38068750ENST00000436793+161141_11420274.0RegionS-adenosyl-L-methionine binding
HgeneWHSC1chr4:1957915chr17:38068750ENST00000503128+1101115_11180648.0RegionS-adenosyl-L-methionine binding
HgeneWHSC1chr4:1957915chr17:38068750ENST00000503128+1101141_11420648.0RegionS-adenosyl-L-methionine binding
HgeneWHSC1chr4:1957915chr17:38068750ENST00000508803+15221115_11189601366.0RegionS-adenosyl-L-methionine binding
HgeneWHSC1chr4:1957915chr17:38068750ENST00000508803+15221141_11429601366.0RegionS-adenosyl-L-methionine binding
HgeneWHSC1chr4:1957915chr17:38068750ENST00000514045+191115_11180630.0RegionS-adenosyl-L-methionine binding
HgeneWHSC1chr4:1957915chr17:38068750ENST00000514045+191141_11420630.0RegionS-adenosyl-L-methionine binding
HgeneWHSC1chr4:1957915chr17:38068750ENST00000382888+5121239_1286308714.0Zinc fingerPHD-type 4%3B atypical
HgeneWHSC1chr4:1957915chr17:38068750ENST00000382888+512667_713308714.0Zinc fingerPHD-type 1
HgeneWHSC1chr4:1957915chr17:38068750ENST00000382888+512714_770308714.0Zinc fingerPHD-type 2
HgeneWHSC1chr4:1957915chr17:38068750ENST00000382888+512831_875308714.0Zinc fingerPHD-type 3
HgeneWHSC1chr4:1957915chr17:38068750ENST00000382891+15221239_12869601366.0Zinc fingerPHD-type 4%3B atypical
HgeneWHSC1chr4:1957915chr17:38068750ENST00000382892+16231239_12869601366.0Zinc fingerPHD-type 4%3B atypical
HgeneWHSC1chr4:1957915chr17:38068750ENST00000382895+17241239_12869601366.0Zinc fingerPHD-type 4%3B atypical
HgeneWHSC1chr4:1957915chr17:38068750ENST00000398261+191239_12860648.0Zinc fingerPHD-type 4%3B atypical
HgeneWHSC1chr4:1957915chr17:38068750ENST00000398261+19667_7130648.0Zinc fingerPHD-type 1
HgeneWHSC1chr4:1957915chr17:38068750ENST00000398261+19714_7700648.0Zinc fingerPHD-type 2
HgeneWHSC1chr4:1957915chr17:38068750ENST00000398261+19831_8750648.0Zinc fingerPHD-type 3
HgeneWHSC1chr4:1957915chr17:38068750ENST00000420906+1111239_12860630.0Zinc fingerPHD-type 4%3B atypical
HgeneWHSC1chr4:1957915chr17:38068750ENST00000420906+111667_7130630.0Zinc fingerPHD-type 1
HgeneWHSC1chr4:1957915chr17:38068750ENST00000420906+111714_7700630.0Zinc fingerPHD-type 2
HgeneWHSC1chr4:1957915chr17:38068750ENST00000420906+111831_8750630.0Zinc fingerPHD-type 3
HgeneWHSC1chr4:1957915chr17:38068750ENST00000436793+161239_12860274.0Zinc fingerPHD-type 4%3B atypical
HgeneWHSC1chr4:1957915chr17:38068750ENST00000436793+16667_7130274.0Zinc fingerPHD-type 1
HgeneWHSC1chr4:1957915chr17:38068750ENST00000436793+16714_7700274.0Zinc fingerPHD-type 2
HgeneWHSC1chr4:1957915chr17:38068750ENST00000436793+16831_8750274.0Zinc fingerPHD-type 3
HgeneWHSC1chr4:1957915chr17:38068750ENST00000503128+1101239_12860648.0Zinc fingerPHD-type 4%3B atypical
HgeneWHSC1chr4:1957915chr17:38068750ENST00000503128+110667_7130648.0Zinc fingerPHD-type 1
HgeneWHSC1chr4:1957915chr17:38068750ENST00000503128+110714_7700648.0Zinc fingerPHD-type 2
HgeneWHSC1chr4:1957915chr17:38068750ENST00000503128+110831_8750648.0Zinc fingerPHD-type 3
HgeneWHSC1chr4:1957915chr17:38068750ENST00000508803+15221239_12869601366.0Zinc fingerPHD-type 4%3B atypical
HgeneWHSC1chr4:1957915chr17:38068750ENST00000514045+191239_12860630.0Zinc fingerPHD-type 4%3B atypical
HgeneWHSC1chr4:1957915chr17:38068750ENST00000514045+19667_7130630.0Zinc fingerPHD-type 1
HgeneWHSC1chr4:1957915chr17:38068750ENST00000514045+19714_7700630.0Zinc fingerPHD-type 2
HgeneWHSC1chr4:1957915chr17:38068750ENST00000514045+19831_8750630.0Zinc fingerPHD-type 3
TgeneGSDMBchr4:1957915chr17:38068750ENST000003094811101_27578404.0RegionTriggers pyroptosis
TgeneGSDMBchr4:1957915chr17:38068750ENST000003603170101_27578417.0RegionTriggers pyroptosis
TgeneGSDMBchr4:1957915chr17:38068750ENST00000394175081_27578395.0RegionTriggers pyroptosis
TgeneGSDMBchr4:1957915chr17:38068750ENST000003941791101_27578412.0RegionTriggers pyroptosis
TgeneGSDMBchr4:1957915chr17:38068750ENST000004185191111_27578417.0RegionTriggers pyroptosis
TgeneGSDMBchr4:1957915chr17:38068750ENST000005205421101_27578408.0RegionTriggers pyroptosis


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Fusion Gene Sequence for WHSC1-GSDMB


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>99189_99189_1_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000382888_GSDMB_chr17_38068750_ENST00000309481_length(transcript)=2637nt_BP=1443nt
CAGCTGTGTGAGAAGCCGGGCAGCCTCCTGCTCTGTGAAGGACCCTGCTGCGGAGCTTTCCACCTCGCCTGCCTTGGGCTTTCCCGGAGG
CCAGAAGGGAGGTTCACCTGCAGCGAGTGTGCCTCAGGTGTCGCCCGGCACAGTCTGGGGTCTGTGAGGATGATGAGAGGACACCTGCAC
AGCCGTGGCCCTTCCTGCCTACTCACCGGGCCCAAGGAGTCTCCTATCTCACGTCAGAACACTTCCTGGGTCAGGAAGACACCTGGAGAG
TCTCCCAGGCCATGGCAGCCCCACAGCAGCACCTCACTTATGGGAGTGTCTGTCTGCCTGCCCAGAATGATAAGTGACTGCTCCACCACT
GGCCAGCTGCTCTCAAGGAGGAAAGGCCTCTTTTCATAGGAGCCCCTTCTTTCAAGCTTCTTGCCAGTTAGACTGGGCCTCCCCAGCCAG
GCTGCCTAGTAAGATTCTCCTGTATTTCAGGTGAAGCTGGAGCTCAGATCGCAGCAAGGTAATCCTTGATGGCTGGATCTTTTTGCTGGA
GAATGCTTGGACTAGTGAGCAAGGTTGGAAACAGGGCCAGGTGCTTTAGCAGCATGGCTGCCTCTGAAGAGGAGTTGCTTGATTTTAGTG
GCTCAGAACTGCAATTTAATTCTTGTTCTTTGCACCTCTCTCTCCACCCCTTCTTTAACTTTTTGTTAGGGATTCACTCATGTTTCGTGT
GTAAAGAGAGCAAGACAGATGTTAAGCGCTGTGTGGTAACTCAGTGTGGAAAATTTTACCATGAGGCTTGTGTGAAAAAATACCCTCTGA
CTGTATTTGAGAGCCGAGGTTTCCGCTGCCCCCTCCACAGCTGTGTGAGCTGCCATGCTTCCAACCCTTCAAACCCAAGGCCGTCAAAAG
GTAAAATGATGCGGTGTGTCCGCTGCCCCGTTGCCTATCACAGCGGGGATGCTTGTCTGGCAGCAGGATGCTCAGTGATCGCCTCCAACA
GCATCATCTGCACTGCCCACTTCACTGCTCGGAAGGGGAAGCGACACCACGCCCACGTCAACGTGAGCTGGTGCTTCGTGTGCTCCAAAG
GGGGGAGCCTTCTGTGCTGTGAGTCCTGCCCAGCGGCCTTCCACCCTGACTGCCTGAACATCGAGATGCCTGACGGCAGCTGGTTCTGCA
ATGACTGCAGGGCTGGGAAGAAGCTGCACTTCCAGGATATCATTTGGGTGAAACTTGGGAACTACAGATGGTGGCCGGCAGAAGTTTGCC
ATCCCAAAAATGTTCCCCCAAATATTCAGAAAATGAAGCACGAGATTGGAGAATTCCCTGTGTTTTTCTTTGGGTCTAAAGATTATTACT
GGACGCATCAGGCGCGAGTGTTCCCGTACATGGAGGGGGACCGGGGCAGCCGCTACCAGGGGGTCAGAGGGATCGGAAGAGTCTTCAAAA
ACGGTCAAAAGGCTGAGTTTCAAATTCTGGATAATGTAGACTCAACGGGAGAGTTGATAGTGAGATTACCCAAAGAAATAACAATTTCAG
GCAGTTTCCAGGGCTTCCACCATCAGAAAATCAAGATATCGGAGAACCGGATATCCCAGCAGTATCTGGCTACCCTTGAAAACAGGAAGC
TGAAGAGGGAACTACCCTTTTCATTCCGATCAATTAATACGAGAGAAAACCTGTATCTGGTGACAGAAACTCTGGAGACGGTAAAGGAGG
AAACCCTGAAAAGCGACCGGCAATATAAATTTTGGAGCCAGATCTCTCAGGGCCATCTCAGCTATAAACACAAGGGCCAAAGGGAAGTGA
CCATCCCCCCAAATCGGGTCCTGAGCTATCGAGTAAAGCAGCTTGTCTTCCCCAACAAGGAGACGATGAAGAAGGATGGTGCTTCATCCT
GTTTAGGAAAGTCTTTGGGTTCGGAGGATTCCAGAAACATGAAGGAGAAGTTGGAGGACATGGAGAGTGTCCTCAAGGACCTGACAGAGG
AGAAGAGAAAAGATGTGCTAAACTCCCTCGCTAAGTGCCTCGGCAAGGAGGATATTCGGCAGGATCTAGAGCAAAGAGTATCTGAGGTCC
TGATTTCCGGGGAGCTACACATGGAGGACCCAGACAAGCCTCTCCTAAGCAGCCTTTTTAATGCTGCTGGGGTCTTGGTAGAAGCGCGTG
CAAAAGCCATTCTGGACTTCCTGGATGCCCTGCTAGAGCTGTCTGAAGAGCAGCAGTTTGTGGCTGAGGCCCTGGAGAAGGGGACCCTTC
CTCTGTTGAAGGACCAGGTGAAATCTGTCATGGAGCAGAACTGGGATGAGCTGGCCAGCAGTCCTCCTGACATGGACTATGACCCTGAGG
CACGAATTCTCTGTGCGCTGTATGTTGTTGTCTCTATCCTGCTGGAGCTGGCTGAGGGGCCTACCTCTGTCTCTTCCTAACTACAAAAGC
CCTTTCTCCCCACAAGCCTCTGGGTTTTCCCTTTACCAGTCTGTCCTCACTGCCATCGCCACTACCATCCTGTCACCAGTGGGACCTCTT
TAAAACAAGCAGCCAACCATTCTTTGATGTATCCCATTCGCTCCATGTTAACATCCAAAACCAGCCTGGATTTCATACATGGACTTCTGA

>99189_99189_1_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000382888_GSDMB_chr17_38068750_ENST00000309481_length(amino acids)=634AA_BP=309
MMAGSFCWRMLGLVSKVGNRARCFSSMAASEEELLDFSGSELQFNSCSLHLSLHPFFNFLLGIHSCFVCKESKTDVKRCVVTQCGKFYHE
ACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKGKMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVNV
SWCFVCSKGGSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCHPKNVPPNIQKMKHEIGEFPVF
FFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKNGQKAEFQILDNVDSTGELIVRLPKEITISGSFQGFHHQKIKISENRISQQY
LATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWSQISQGHLSYKHKGQREVTIPPNRVLSYRVKQLVFPNKET
MKKDGASSCLGKSLGSEDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELHMEDPDKPLLSSLFNA
AGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQNWDELASSPPDMDYDPEARILCALYVVVSILLELAEGPT

--------------------------------------------------------------
>99189_99189_2_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000382888_GSDMB_chr17_38068750_ENST00000360317_length(transcript)=2676nt_BP=1443nt
CAGCTGTGTGAGAAGCCGGGCAGCCTCCTGCTCTGTGAAGGACCCTGCTGCGGAGCTTTCCACCTCGCCTGCCTTGGGCTTTCCCGGAGG
CCAGAAGGGAGGTTCACCTGCAGCGAGTGTGCCTCAGGTGTCGCCCGGCACAGTCTGGGGTCTGTGAGGATGATGAGAGGACACCTGCAC
AGCCGTGGCCCTTCCTGCCTACTCACCGGGCCCAAGGAGTCTCCTATCTCACGTCAGAACACTTCCTGGGTCAGGAAGACACCTGGAGAG
TCTCCCAGGCCATGGCAGCCCCACAGCAGCACCTCACTTATGGGAGTGTCTGTCTGCCTGCCCAGAATGATAAGTGACTGCTCCACCACT
GGCCAGCTGCTCTCAAGGAGGAAAGGCCTCTTTTCATAGGAGCCCCTTCTTTCAAGCTTCTTGCCAGTTAGACTGGGCCTCCCCAGCCAG
GCTGCCTAGTAAGATTCTCCTGTATTTCAGGTGAAGCTGGAGCTCAGATCGCAGCAAGGTAATCCTTGATGGCTGGATCTTTTTGCTGGA
GAATGCTTGGACTAGTGAGCAAGGTTGGAAACAGGGCCAGGTGCTTTAGCAGCATGGCTGCCTCTGAAGAGGAGTTGCTTGATTTTAGTG
GCTCAGAACTGCAATTTAATTCTTGTTCTTTGCACCTCTCTCTCCACCCCTTCTTTAACTTTTTGTTAGGGATTCACTCATGTTTCGTGT
GTAAAGAGAGCAAGACAGATGTTAAGCGCTGTGTGGTAACTCAGTGTGGAAAATTTTACCATGAGGCTTGTGTGAAAAAATACCCTCTGA
CTGTATTTGAGAGCCGAGGTTTCCGCTGCCCCCTCCACAGCTGTGTGAGCTGCCATGCTTCCAACCCTTCAAACCCAAGGCCGTCAAAAG
GTAAAATGATGCGGTGTGTCCGCTGCCCCGTTGCCTATCACAGCGGGGATGCTTGTCTGGCAGCAGGATGCTCAGTGATCGCCTCCAACA
GCATCATCTGCACTGCCCACTTCACTGCTCGGAAGGGGAAGCGACACCACGCCCACGTCAACGTGAGCTGGTGCTTCGTGTGCTCCAAAG
GGGGGAGCCTTCTGTGCTGTGAGTCCTGCCCAGCGGCCTTCCACCCTGACTGCCTGAACATCGAGATGCCTGACGGCAGCTGGTTCTGCA
ATGACTGCAGGGCTGGGAAGAAGCTGCACTTCCAGGATATCATTTGGGTGAAACTTGGGAACTACAGATGGTGGCCGGCAGAAGTTTGCC
ATCCCAAAAATGTTCCCCCAAATATTCAGAAAATGAAGCACGAGATTGGAGAATTCCCTGTGTTTTTCTTTGGGTCTAAAGATTATTACT
GGACGCATCAGGCGCGAGTGTTCCCGTACATGGAGGGGGACCGGGGCAGCCGCTACCAGGGGGTCAGAGGGATCGGAAGAGTCTTCAAAA
ACGGTCAAAAGGCTGAGTTTCAAATTCTGGATAATGTAGACTCAACGGGAGAGTTGATAGTGAGATTACCCAAAGAAATAACAATTTCAG
GCAGTTTCCAGGGCTTCCACCATCAGAAAATCAAGATATCGGAGAACCGGATATCCCAGCAGTATCTGGCTACCCTTGAAAACAGGAAGC
TGAAGAGGGAACTACCCTTTTCATTCCGATCAATTAATACGAGAGAAAACCTGTATCTGGTGACAGAAACTCTGGAGACGGTAAAGGAGG
AAACCCTGAAAAGCGACCGGCAATATAAATTTTGGAGCCAGATCTCTCAGGGCCATCTCAGCTATAAACACAAGGGCCAAAGGGAAGTGA
CCATCCCCCCAAATCGGGTCCTGAGCTATCGAGTAAAGCAGCTTGTCTTCCCCAACAAGGAGACGATGAATATTCATTTCAGGGGCAAAA
CAAAATCCTTTCCAGAAGAGAAGGATGGTGCTTCATCCTGTTTAGGAAAGTCTTTGGGTTCGGAGGATTCCAGAAACATGAAGGAGAAGT
TGGAGGACATGGAGAGTGTCCTCAAGGACCTGACAGAGGAGAAGAGAAAAGATGTGCTAAACTCCCTCGCTAAGTGCCTCGGCAAGGAGG
ATATTCGGCAGGATCTAGAGCAAAGAGTATCTGAGGTCCTGATTTCCGGGGAGCTACACATGGAGGACCCAGACAAGCCTCTCCTAAGCA
GCCTTTTTAATGCTGCTGGGGTCTTGGTAGAAGCGCGTGCAAAAGCCATTCTGGACTTCCTGGATGCCCTGCTAGAGCTGTCTGAAGAGC
AGCAGTTTGTGGCTGAGGCCCTGGAGAAGGGGACCCTTCCTCTGTTGAAGGACCAGGTGAAATCTGTCATGGAGCAGAACTGGGATGAGC
TGGCCAGCAGTCCTCCTGACATGGACTATGACCCTGAGGCACGAATTCTCTGTGCGCTGTATGTTGTTGTCTCTATCCTGCTGGAGCTGG
CTGAGGGGCCTACCTCTGTCTCTTCCTAACTACAAAAGCCCTTTCTCCCCACAAGCCTCTGGGTTTTCCCTTTACCAGTCTGTCCTCACT
GCCATCGCCACTACCATCCTGTCACCAGTGGGACCTCTTTAAAACAAGCAGCCAACCATTCTTTGATGTATCCCATTCGCTCCATGTTAA

>99189_99189_2_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000382888_GSDMB_chr17_38068750_ENST00000360317_length(amino acids)=647AA_BP=309
MMAGSFCWRMLGLVSKVGNRARCFSSMAASEEELLDFSGSELQFNSCSLHLSLHPFFNFLLGIHSCFVCKESKTDVKRCVVTQCGKFYHE
ACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKGKMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVNV
SWCFVCSKGGSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCHPKNVPPNIQKMKHEIGEFPVF
FFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKNGQKAEFQILDNVDSTGELIVRLPKEITISGSFQGFHHQKIKISENRISQQY
LATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWSQISQGHLSYKHKGQREVTIPPNRVLSYRVKQLVFPNKET
MNIHFRGKTKSFPEEKDGASSCLGKSLGSEDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELHME
DPDKPLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQNWDELASSPPDMDYDPEARILCALYV

--------------------------------------------------------------
>99189_99189_3_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000382888_GSDMB_chr17_38068750_ENST00000394175_length(transcript)=2610nt_BP=1443nt
CAGCTGTGTGAGAAGCCGGGCAGCCTCCTGCTCTGTGAAGGACCCTGCTGCGGAGCTTTCCACCTCGCCTGCCTTGGGCTTTCCCGGAGG
CCAGAAGGGAGGTTCACCTGCAGCGAGTGTGCCTCAGGTGTCGCCCGGCACAGTCTGGGGTCTGTGAGGATGATGAGAGGACACCTGCAC
AGCCGTGGCCCTTCCTGCCTACTCACCGGGCCCAAGGAGTCTCCTATCTCACGTCAGAACACTTCCTGGGTCAGGAAGACACCTGGAGAG
TCTCCCAGGCCATGGCAGCCCCACAGCAGCACCTCACTTATGGGAGTGTCTGTCTGCCTGCCCAGAATGATAAGTGACTGCTCCACCACT
GGCCAGCTGCTCTCAAGGAGGAAAGGCCTCTTTTCATAGGAGCCCCTTCTTTCAAGCTTCTTGCCAGTTAGACTGGGCCTCCCCAGCCAG
GCTGCCTAGTAAGATTCTCCTGTATTTCAGGTGAAGCTGGAGCTCAGATCGCAGCAAGGTAATCCTTGATGGCTGGATCTTTTTGCTGGA
GAATGCTTGGACTAGTGAGCAAGGTTGGAAACAGGGCCAGGTGCTTTAGCAGCATGGCTGCCTCTGAAGAGGAGTTGCTTGATTTTAGTG
GCTCAGAACTGCAATTTAATTCTTGTTCTTTGCACCTCTCTCTCCACCCCTTCTTTAACTTTTTGTTAGGGATTCACTCATGTTTCGTGT
GTAAAGAGAGCAAGACAGATGTTAAGCGCTGTGTGGTAACTCAGTGTGGAAAATTTTACCATGAGGCTTGTGTGAAAAAATACCCTCTGA
CTGTATTTGAGAGCCGAGGTTTCCGCTGCCCCCTCCACAGCTGTGTGAGCTGCCATGCTTCCAACCCTTCAAACCCAAGGCCGTCAAAAG
GTAAAATGATGCGGTGTGTCCGCTGCCCCGTTGCCTATCACAGCGGGGATGCTTGTCTGGCAGCAGGATGCTCAGTGATCGCCTCCAACA
GCATCATCTGCACTGCCCACTTCACTGCTCGGAAGGGGAAGCGACACCACGCCCACGTCAACGTGAGCTGGTGCTTCGTGTGCTCCAAAG
GGGGGAGCCTTCTGTGCTGTGAGTCCTGCCCAGCGGCCTTCCACCCTGACTGCCTGAACATCGAGATGCCTGACGGCAGCTGGTTCTGCA
ATGACTGCAGGGCTGGGAAGAAGCTGCACTTCCAGGATATCATTTGGGTGAAACTTGGGAACTACAGATGGTGGCCGGCAGAAGTTTGCC
ATCCCAAAAATGTTCCCCCAAATATTCAGAAAATGAAGCACGAGATTGGAGAATTCCCTGTGTTTTTCTTTGGGTCTAAAGATTATTACT
GGACGCATCAGGCGCGAGTGTTCCCGTACATGGAGGGGGACCGGGGCAGCCGCTACCAGGGGGTCAGAGGGATCGGAAGAGTCTTCAAAA
ACGGTCAAAAGGCTGAGTTTCAAATTCTGGATAATGTAGACTCAACGGGAGAGTTGATAGTGAGATTACCCAAAGAAATAACAATTTCAG
GCAGTTTCCAGGGCTTCCACCATCAGAAAATCAAGATATCGGAGAACCGGATATCCCAGCAGTATCTGGCTACCCTTGAAAACAGGAAGC
TGAAGAGGGAACTACCCTTTTCATTCCGATCAATTAATACGAGAGAAAACCTGTATCTGGTGACAGAAACTCTGGAGACGGTAAAGGAGG
AAACCCTGAAAAGCGACCGGCAATATAAATTTTGGAGCCAGATCTCTCAGGGCCATCTCAGCTATAAACACAAGGGCCAAAGGGAAGTGA
CCATCCCCCCAAATCGGGTCCTGAGCTATCGAGTAAAGCAGCTTGTCTTCCCCAACAAGGAGACGATGAGAAAGTCTTTGGGTTCGGAGG
ATTCCAGAAACATGAAGGAGAAGTTGGAGGACATGGAGAGTGTCCTCAAGGACCTGACAGAGGAGAAGAGAAAAGATGTGCTAAACTCCC
TCGCTAAGTGCCTCGGCAAGGAGGATATTCGGCAGGATCTAGAGCAAAGAGTATCTGAGGTCCTGATTTCCGGGGAGCTACACATGGAGG
ACCCAGACAAGCCTCTCCTAAGCAGCCTTTTTAATGCTGCTGGGGTCTTGGTAGAAGCGCGTGCAAAAGCCATTCTGGACTTCCTGGATG
CCCTGCTAGAGCTGTCTGAAGAGCAGCAGTTTGTGGCTGAGGCCCTGGAGAAGGGGACCCTTCCTCTGTTGAAGGACCAGGTGAAATCTG
TCATGGAGCAGAACTGGGATGAGCTGGCCAGCAGTCCTCCTGACATGGACTATGACCCTGAGGCACGAATTCTCTGTGCGCTGTATGTTG
TTGTCTCTATCCTGCTGGAGCTGGCTGAGGGGCCTACCTCTGTCTCTTCCTAACTACAAAAGCCCTTTCTCCCCACAAGCCTCTGGGTTT
TCCCTTTACCAGTCTGTCCTCACTGCCATCGCCACTACCATCCTGTCACCAGTGGGACCTCTTTAAAACAAGCAGCCAACCATTCTTTGA
TGTATCCCATTCGCTCCATGTTAACATCCAAAACCAGCCTGGATTTCATACATGGACTTCTGATTAAAAGTGGCAGGTTGTGCATGTTAA

>99189_99189_3_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000382888_GSDMB_chr17_38068750_ENST00000394175_length(amino acids)=625AA_BP=309
MMAGSFCWRMLGLVSKVGNRARCFSSMAASEEELLDFSGSELQFNSCSLHLSLHPFFNFLLGIHSCFVCKESKTDVKRCVVTQCGKFYHE
ACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKGKMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVNV
SWCFVCSKGGSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCHPKNVPPNIQKMKHEIGEFPVF
FFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKNGQKAEFQILDNVDSTGELIVRLPKEITISGSFQGFHHQKIKISENRISQQY
LATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWSQISQGHLSYKHKGQREVTIPPNRVLSYRVKQLVFPNKET
MRKSLGSEDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELHMEDPDKPLLSSLFNAAGVLVEARA

--------------------------------------------------------------
>99189_99189_4_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000382888_GSDMB_chr17_38068750_ENST00000394179_length(transcript)=2659nt_BP=1443nt
CAGCTGTGTGAGAAGCCGGGCAGCCTCCTGCTCTGTGAAGGACCCTGCTGCGGAGCTTTCCACCTCGCCTGCCTTGGGCTTTCCCGGAGG
CCAGAAGGGAGGTTCACCTGCAGCGAGTGTGCCTCAGGTGTCGCCCGGCACAGTCTGGGGTCTGTGAGGATGATGAGAGGACACCTGCAC
AGCCGTGGCCCTTCCTGCCTACTCACCGGGCCCAAGGAGTCTCCTATCTCACGTCAGAACACTTCCTGGGTCAGGAAGACACCTGGAGAG
TCTCCCAGGCCATGGCAGCCCCACAGCAGCACCTCACTTATGGGAGTGTCTGTCTGCCTGCCCAGAATGATAAGTGACTGCTCCACCACT
GGCCAGCTGCTCTCAAGGAGGAAAGGCCTCTTTTCATAGGAGCCCCTTCTTTCAAGCTTCTTGCCAGTTAGACTGGGCCTCCCCAGCCAG
GCTGCCTAGTAAGATTCTCCTGTATTTCAGGTGAAGCTGGAGCTCAGATCGCAGCAAGGTAATCCTTGATGGCTGGATCTTTTTGCTGGA
GAATGCTTGGACTAGTGAGCAAGGTTGGAAACAGGGCCAGGTGCTTTAGCAGCATGGCTGCCTCTGAAGAGGAGTTGCTTGATTTTAGTG
GCTCAGAACTGCAATTTAATTCTTGTTCTTTGCACCTCTCTCTCCACCCCTTCTTTAACTTTTTGTTAGGGATTCACTCATGTTTCGTGT
GTAAAGAGAGCAAGACAGATGTTAAGCGCTGTGTGGTAACTCAGTGTGGAAAATTTTACCATGAGGCTTGTGTGAAAAAATACCCTCTGA
CTGTATTTGAGAGCCGAGGTTTCCGCTGCCCCCTCCACAGCTGTGTGAGCTGCCATGCTTCCAACCCTTCAAACCCAAGGCCGTCAAAAG
GTAAAATGATGCGGTGTGTCCGCTGCCCCGTTGCCTATCACAGCGGGGATGCTTGTCTGGCAGCAGGATGCTCAGTGATCGCCTCCAACA
GCATCATCTGCACTGCCCACTTCACTGCTCGGAAGGGGAAGCGACACCACGCCCACGTCAACGTGAGCTGGTGCTTCGTGTGCTCCAAAG
GGGGGAGCCTTCTGTGCTGTGAGTCCTGCCCAGCGGCCTTCCACCCTGACTGCCTGAACATCGAGATGCCTGACGGCAGCTGGTTCTGCA
ATGACTGCAGGGCTGGGAAGAAGCTGCACTTCCAGGATATCATTTGGGTGAAACTTGGGAACTACAGATGGTGGCCGGCAGAAGTTTGCC
ATCCCAAAAATGTTCCCCCAAATATTCAGAAAATGAAGCACGAGATTGGAGAATTCCCTGTGTTTTTCTTTGGGTCTAAAGATTATTACT
GGACGCATCAGGCGCGAGTGTTCCCGTACATGGAGGGGGACCGGGGCAGCCGCTACCAGGGGGTCAGAGGGATCGGAAGAGTCTTCAAAA
ACGGTCAAAAGGCTGAGTTTCAAATTCTGGATAATGTAGACTCAACGGGAGAGTTGATAGTGAGATTACCCAAAGAAATAACAATTTCAG
GCAGTTTCCAGGGCTTCCACCATCAGAAAATCAAGATATCGGAGAACCGGATATCCCAGCAGTATCTGGCTACCCTTGAAAACAGGAAGC
TGAAGAGGGAACTACCCTTTTCATTCCGATCAATTAATACGAGAGAAAACCTGTATCTGGTGACAGAAACTCTGGAGACGGTAAAGGAGG
AAACCCTGAAAAGCGACCGGCAATATAAATTTTGGAGCCAGATCTCTCAGGGCCATCTCAGCTATAAACACAAGGGCCAAAGGGAAGTGA
CCATCCCCCCAAATCGGGTCCTGAGCTATCGAGTAAAGCAGCTTGTCTTCCCCAACAAGGAGACGATGAGTGCTGGTTTAGATATTCATT
TCAGGGGCAAAACAAAATCCTTTCCAGAAGGAAAGTCTTTGGGTTCGGAGGATTCCAGAAACATGAAGGAGAAGTTGGAGGACATGGAGA
GTGTCCTCAAGGACCTGACAGAGGAGAAGAGAAAAGATGTGCTAAACTCCCTCGCTAAGTGCCTCGGCAAGGAGGATATTCGGCAGGATC
TAGAGCAAAGAGTATCTGAGGTCCTGATTTCCGGGGAGCTACACATGGAGGACCCAGACAAGCCTCTCCTAAGCAGCCTTTTTAATGCTG
CTGGGGTCTTGGTAGAAGCGCGTGCAAAAGCCATTCTGGACTTCCTGGATGCCCTGCTAGAGCTGTCTGAAGAGCAGCAGTTTGTGGCTG
AGGCCCTGGAGAAGGGGACCCTTCCTCTGTTGAAGGACCAGGTGAAATCTGTCATGGAGCAGAACTGGGATGAGCTGGCCAGCAGTCCTC
CTGACATGGACTATGACCCTGAGGCACGAATTCTCTGTGCGCTGTATGTTGTTGTCTCTATCCTGCTGGAGCTGGCTGAGGGGCCTACCT
CTGTCTCTTCCTAACTACAAAAGCCCTTTCTCCCCACAAGCCTCTGGGTTTTCCCTTTACCAGTCTGTCCTCACTGCCATCGCCACTACC
ATCCTGTCACCAGTGGGACCTCTTTAAAACAAGCAGCCAACCATTCTTTGATGTATCCCATTCGCTCCATGTTAACATCCAAAACCAGCC

>99189_99189_4_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000382888_GSDMB_chr17_38068750_ENST00000394179_length(amino acids)=642AA_BP=309
MMAGSFCWRMLGLVSKVGNRARCFSSMAASEEELLDFSGSELQFNSCSLHLSLHPFFNFLLGIHSCFVCKESKTDVKRCVVTQCGKFYHE
ACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKGKMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVNV
SWCFVCSKGGSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCHPKNVPPNIQKMKHEIGEFPVF
FFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKNGQKAEFQILDNVDSTGELIVRLPKEITISGSFQGFHHQKIKISENRISQQY
LATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWSQISQGHLSYKHKGQREVTIPPNRVLSYRVKQLVFPNKET
MSAGLDIHFRGKTKSFPEGKSLGSEDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELHMEDPDKP
LLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQNWDELASSPPDMDYDPEARILCALYVVVSIL

--------------------------------------------------------------
>99189_99189_5_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000382888_GSDMB_chr17_38068750_ENST00000418519_length(transcript)=2674nt_BP=1443nt
CAGCTGTGTGAGAAGCCGGGCAGCCTCCTGCTCTGTGAAGGACCCTGCTGCGGAGCTTTCCACCTCGCCTGCCTTGGGCTTTCCCGGAGG
CCAGAAGGGAGGTTCACCTGCAGCGAGTGTGCCTCAGGTGTCGCCCGGCACAGTCTGGGGTCTGTGAGGATGATGAGAGGACACCTGCAC
AGCCGTGGCCCTTCCTGCCTACTCACCGGGCCCAAGGAGTCTCCTATCTCACGTCAGAACACTTCCTGGGTCAGGAAGACACCTGGAGAG
TCTCCCAGGCCATGGCAGCCCCACAGCAGCACCTCACTTATGGGAGTGTCTGTCTGCCTGCCCAGAATGATAAGTGACTGCTCCACCACT
GGCCAGCTGCTCTCAAGGAGGAAAGGCCTCTTTTCATAGGAGCCCCTTCTTTCAAGCTTCTTGCCAGTTAGACTGGGCCTCCCCAGCCAG
GCTGCCTAGTAAGATTCTCCTGTATTTCAGGTGAAGCTGGAGCTCAGATCGCAGCAAGGTAATCCTTGATGGCTGGATCTTTTTGCTGGA
GAATGCTTGGACTAGTGAGCAAGGTTGGAAACAGGGCCAGGTGCTTTAGCAGCATGGCTGCCTCTGAAGAGGAGTTGCTTGATTTTAGTG
GCTCAGAACTGCAATTTAATTCTTGTTCTTTGCACCTCTCTCTCCACCCCTTCTTTAACTTTTTGTTAGGGATTCACTCATGTTTCGTGT
GTAAAGAGAGCAAGACAGATGTTAAGCGCTGTGTGGTAACTCAGTGTGGAAAATTTTACCATGAGGCTTGTGTGAAAAAATACCCTCTGA
CTGTATTTGAGAGCCGAGGTTTCCGCTGCCCCCTCCACAGCTGTGTGAGCTGCCATGCTTCCAACCCTTCAAACCCAAGGCCGTCAAAAG
GTAAAATGATGCGGTGTGTCCGCTGCCCCGTTGCCTATCACAGCGGGGATGCTTGTCTGGCAGCAGGATGCTCAGTGATCGCCTCCAACA
GCATCATCTGCACTGCCCACTTCACTGCTCGGAAGGGGAAGCGACACCACGCCCACGTCAACGTGAGCTGGTGCTTCGTGTGCTCCAAAG
GGGGGAGCCTTCTGTGCTGTGAGTCCTGCCCAGCGGCCTTCCACCCTGACTGCCTGAACATCGAGATGCCTGACGGCAGCTGGTTCTGCA
ATGACTGCAGGGCTGGGAAGAAGCTGCACTTCCAGGATATCATTTGGGTGAAACTTGGGAACTACAGATGGTGGCCGGCAGAAGTTTGCC
ATCCCAAAAATGTTCCCCCAAATATTCAGAAAATGAAGCACGAGATTGGAGAATTCCCTGTGTTTTTCTTTGGGTCTAAAGATTATTACT
GGACGCATCAGGCGCGAGTGTTCCCGTACATGGAGGGGGACCGGGGCAGCCGCTACCAGGGGGTCAGAGGGATCGGAAGAGTCTTCAAAA
ACGGTCAAAAGGCTGAGTTTCAAATTCTGGATAATGTAGACTCAACGGGAGAGTTGATAGTGAGATTACCCAAAGAAATAACAATTTCAG
GCAGTTTCCAGGGCTTCCACCATCAGAAAATCAAGATATCGGAGAACCGGATATCCCAGCAGTATCTGGCTACCCTTGAAAACAGGAAGC
TGAAGAGGGAACTACCCTTTTCATTCCGATCAATTAATACGAGAGAAAACCTGTATCTGGTGACAGAAACTCTGGAGACGGTAAAGGAGG
AAACCCTGAAAAGCGACCGGCAATATAAATTTTGGAGCCAGATCTCTCAGGGCCATCTCAGCTATAAACACAAGGGCCAAAGGGAAGTGA
CCATCCCCCCAAATCGGGTCCTGAGCTATCGAGTAAAGCAGCTTGTCTTCCCCAACAAGGAGACGATGAATATTCATTTCAGGGGCAAAA
CAAAATCCTTTCCAGAAGAGAAGGATGGTGCTTCATCCTGTTTAGGAAAGTCTTTGGGTTCGGAGGATTCCAGAAACATGAAGGAGAAGT
TGGAGGACATGGAGAGTGTCCTCAAGGACCTGACAGAGGAGAAGAGAAAAGATGTGCTAAACTCCCTCGCTAAGTGCCTCGGCAAGGAGG
ATATTCGGCAGGATCTAGAGCAAAGAGTATCTGAGGTCCTGATTTCCGGGGAGCTACACATGGAGGACCCAGACAAGCCTCTCCTAAGCA
GCCTTTTTAATGCTGCTGGGGTCTTGGTAGAAGCGCGTGCAAAAGCCATTCTGGACTTCCTGGATGCCCTGCTAGAGCTGTCTGAAGAGC
AGCAGTTTGTGGCTGAGGCCCTGGAGAAGGGGACCCTTCCTCTGTTGAAGGACCAGGTGAAATCTGTCATGGAGCAGAACTGGGATGAGC
TGGCCAGCAGTCCTCCTGACATGGACTATGACCCTGAGGCACGAATTCTCTGTGCGCTGTATGTTGTTGTCTCTATCCTGCTGGAGCTGG
CTGAGGGGCCTACCTCTGTCTCTTCCTAACTACAAAAGCCCTTTCTCCCCACAAGCCTCTGGGTTTTCCCTTTACCAGTCTGTCCTCACT
GCCATCGCCACTACCATCCTGTCACCAGTGGGACCTCTTTAAAACAAGCAGCCAACCATTCTTTGATGTATCCCATTCGCTCCATGTTAA

>99189_99189_5_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000382888_GSDMB_chr17_38068750_ENST00000418519_length(amino acids)=647AA_BP=309
MMAGSFCWRMLGLVSKVGNRARCFSSMAASEEELLDFSGSELQFNSCSLHLSLHPFFNFLLGIHSCFVCKESKTDVKRCVVTQCGKFYHE
ACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKGKMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVNV
SWCFVCSKGGSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCHPKNVPPNIQKMKHEIGEFPVF
FFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKNGQKAEFQILDNVDSTGELIVRLPKEITISGSFQGFHHQKIKISENRISQQY
LATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWSQISQGHLSYKHKGQREVTIPPNRVLSYRVKQLVFPNKET
MNIHFRGKTKSFPEEKDGASSCLGKSLGSEDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELHME
DPDKPLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQNWDELASSPPDMDYDPEARILCALYV

--------------------------------------------------------------
>99189_99189_6_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000382888_GSDMB_chr17_38068750_ENST00000520542_length(transcript)=2647nt_BP=1443nt
CAGCTGTGTGAGAAGCCGGGCAGCCTCCTGCTCTGTGAAGGACCCTGCTGCGGAGCTTTCCACCTCGCCTGCCTTGGGCTTTCCCGGAGG
CCAGAAGGGAGGTTCACCTGCAGCGAGTGTGCCTCAGGTGTCGCCCGGCACAGTCTGGGGTCTGTGAGGATGATGAGAGGACACCTGCAC
AGCCGTGGCCCTTCCTGCCTACTCACCGGGCCCAAGGAGTCTCCTATCTCACGTCAGAACACTTCCTGGGTCAGGAAGACACCTGGAGAG
TCTCCCAGGCCATGGCAGCCCCACAGCAGCACCTCACTTATGGGAGTGTCTGTCTGCCTGCCCAGAATGATAAGTGACTGCTCCACCACT
GGCCAGCTGCTCTCAAGGAGGAAAGGCCTCTTTTCATAGGAGCCCCTTCTTTCAAGCTTCTTGCCAGTTAGACTGGGCCTCCCCAGCCAG
GCTGCCTAGTAAGATTCTCCTGTATTTCAGGTGAAGCTGGAGCTCAGATCGCAGCAAGGTAATCCTTGATGGCTGGATCTTTTTGCTGGA
GAATGCTTGGACTAGTGAGCAAGGTTGGAAACAGGGCCAGGTGCTTTAGCAGCATGGCTGCCTCTGAAGAGGAGTTGCTTGATTTTAGTG
GCTCAGAACTGCAATTTAATTCTTGTTCTTTGCACCTCTCTCTCCACCCCTTCTTTAACTTTTTGTTAGGGATTCACTCATGTTTCGTGT
GTAAAGAGAGCAAGACAGATGTTAAGCGCTGTGTGGTAACTCAGTGTGGAAAATTTTACCATGAGGCTTGTGTGAAAAAATACCCTCTGA
CTGTATTTGAGAGCCGAGGTTTCCGCTGCCCCCTCCACAGCTGTGTGAGCTGCCATGCTTCCAACCCTTCAAACCCAAGGCCGTCAAAAG
GTAAAATGATGCGGTGTGTCCGCTGCCCCGTTGCCTATCACAGCGGGGATGCTTGTCTGGCAGCAGGATGCTCAGTGATCGCCTCCAACA
GCATCATCTGCACTGCCCACTTCACTGCTCGGAAGGGGAAGCGACACCACGCCCACGTCAACGTGAGCTGGTGCTTCGTGTGCTCCAAAG
GGGGGAGCCTTCTGTGCTGTGAGTCCTGCCCAGCGGCCTTCCACCCTGACTGCCTGAACATCGAGATGCCTGACGGCAGCTGGTTCTGCA
ATGACTGCAGGGCTGGGAAGAAGCTGCACTTCCAGGATATCATTTGGGTGAAACTTGGGAACTACAGATGGTGGCCGGCAGAAGTTTGCC
ATCCCAAAAATGTTCCCCCAAATATTCAGAAAATGAAGCACGAGATTGGAGAATTCCCTGTGTTTTTCTTTGGGTCTAAAGATTATTACT
GGACGCATCAGGCGCGAGTGTTCCCGTACATGGAGGGGGACCGGGGCAGCCGCTACCAGGGGGTCAGAGGGATCGGAAGAGTCTTCAAAA
ACGGTCAAAAGGCTGAGTTTCAAATTCTGGATAATGTAGACTCAACGGGAGAGTTGATAGTGAGATTACCCAAAGAAATAACAATTTCAG
GCAGTTTCCAGGGCTTCCACCATCAGAAAATCAAGATATCGGAGAACCGGATATCCCAGCAGTATCTGGCTACCCTTGAAAACAGGAAGC
TGAAGAGGGAACTACCCTTTTCATTCCGATCAATTAATACGAGAGAAAACCTGTATCTGGTGACAGAAACTCTGGAGACGGTAAAGGAGG
AAACCCTGAAAAGCGACCGGCAATATAAATTTTGGAGCCAGATCTCTCAGGGCCATCTCAGCTATAAACACAAGGGCCAAAGGGAAGTGA
CCATCCCCCCAAATCGGGTCCTGAGCTATCGAGTAAAGCAGCTTGTCTTCCCCAACAAGGAGACGATGAATATTCATTTCAGGGGCAAAA
CAAAATCCTTTCCAGAAGGAAAGTCTTTGGGTTCGGAGGATTCCAGAAACATGAAGGAGAAGTTGGAGGACATGGAGAGTGTCCTCAAGG
ACCTGACAGAGGAGAAGAGAAAAGATGTGCTAAACTCCCTCGCTAAGTGCCTCGGCAAGGAGGATATTCGGCAGGATCTAGAGCAAAGAG
TATCTGAGGTCCTGATTTCCGGGGAGCTACACATGGAGGACCCAGACAAGCCTCTCCTAAGCAGCCTTTTTAATGCTGCTGGGGTCTTGG
TAGAAGCGCGTGCAAAAGCCATTCTGGACTTCCTGGATGCCCTGCTAGAGCTGTCTGAAGAGCAGCAGTTTGTGGCTGAGGCCCTGGAGA
AGGGGACCCTTCCTCTGTTGAAGGACCAGGTGAAATCTGTCATGGAGCAGAACTGGGATGAGCTGGCCAGCAGTCCTCCTGACATGGACT
ATGACCCTGAGGCACGAATTCTCTGTGCGCTGTATGTTGTTGTCTCTATCCTGCTGGAGCTGGCTGAGGGGCCTACCTCTGTCTCTTCCT
AACTACAAAAGCCCTTTCTCCCCACAAGCCTCTGGGTTTTCCCTTTACCAGTCTGTCCTCACTGCCATCGCCACTACCATCCTGTCACCA
GTGGGACCTCTTTAAAACAAGCAGCCAACCATTCTTTGATGTATCCCATTCGCTCCATGTTAACATCCAAAACCAGCCTGGATTTCATAC

>99189_99189_6_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000382888_GSDMB_chr17_38068750_ENST00000520542_length(amino acids)=638AA_BP=309
MMAGSFCWRMLGLVSKVGNRARCFSSMAASEEELLDFSGSELQFNSCSLHLSLHPFFNFLLGIHSCFVCKESKTDVKRCVVTQCGKFYHE
ACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKGKMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVNV
SWCFVCSKGGSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCHPKNVPPNIQKMKHEIGEFPVF
FFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKNGQKAEFQILDNVDSTGELIVRLPKEITISGSFQGFHHQKIKISENRISQQY
LATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWSQISQGHLSYKHKGQREVTIPPNRVLSYRVKQLVFPNKET
MNIHFRGKTKSFPEGKSLGSEDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELHMEDPDKPLLSS
LFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQNWDELASSPPDMDYDPEARILCALYVVVSILLELA

--------------------------------------------------------------
>99189_99189_7_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000382891_GSDMB_chr17_38068750_ENST00000309481_length(transcript)=4214nt_BP=3020nt
TGGTCTTGAACTCCTGACCTTGTGATCCGCTCGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGTGCCTGTCCTAGAA
CCACTGGTAACTCTTAACTGTGTTCTAAGAACGGAAGCATCTGGGCTGGATGGAATTTAGCATCAAGCAGAGTCCCCTTTCTGTTCAGAG
TGTTGTAAAGTGCATAAAGATGAAGCAGGCACCAGAAATCCTCGGCAGTGCCAACGGGAAGACTCCGAGCTGCGAGGTGAACCGCGAGTG
TTCTGTGTTCCTCAGCAAAGCCCAGCTCTCCAGTAGCCTGCAGGAGGGGGTCATGCAGAAGTTTAACGGCCACGACGCCCTGCCCTTTAT
TCCAGCCGACAAGCTGAAAGATCTTACTTCCCGGGTGTTTAATGGAGAACCCGGCGCACACGATGCCAAACTGCGTTTTGAGTCCCAGGA
AATGAAAGGGATTGGGACACCCCCTAACACTACCCCTATCAAAAATGGCTCTCCAGAAATTAAGCTGAAAATCACCAAAACATACATGAA
TGGGAAGCCTCTCTTTGAATCTTCCATTTGTGGTGACAGTGCTGCTGATGTGTCTCAGTCAGAAGAAAATGGACAAAAACCAGAAAACAA
GGCGAGAAGGAACAGGAAGAGGAGCATAAAATATGACTCCTTGCTGGAGCAGGGCCTTGTCGAAGCAGCTCTTGTGTCTAAGATCTCAAG
TCCTTCAGATAAAAAGATTCCAGCTAAGAAAGAGTCTTGTCCAAACACTGGAAGAGACAAAGACCACCTGTTGAAATACAACGTTGGTGA
TTTGGTGTGGTCCAAAGTGTCGGGTTACCCTTGGTGGCCTTGCATGGTTTCTGCAGATCCACTCCTTCACAGCTATACCAAACTTAAAGG
TCAGAAAAAGAGTGCACGCCAGTATCACGTACAGTTCTTTGGTGACGCCCCAGAAAGAGCTTGGATATTTGAGAAGAGCCTCGTAGCTTT
TGAAGGAGAAGGACAGTTTGAAAAATTATGCCAGGAAAGTGCCAAGCAGGCACCCACGAAAGCTGAGAAAATTAAGCTATTGAAACCAAT
TTCAGGGAAATTGAGGGCCCAGTGGGAAATGGGCATTGTTCAAGCAGAAGAAGCTGCAAGCATGTCAGTGGAGGAGCGGAAAGCCAAGTT
CACCTTTCTCTATGTGGGGGACCAGCTTCATCTCAACCCTCAAGTAGCCAAGGAGGCTGGCATTGCTGCAGAGTCTTTGGGAGAAATGGC
AGAATCCTCAGGAGTCAGTGAAGAAGCTGCTGAAAACCCCAAGTCTGTGAGAGAAGAGTGCATTCCCATGAAGAGAAGGCGGAGGGCCAA
ACTGTGTAGCTCTGCAGAGACCCTGGAGAGTCACCCCGACATAGGGAAGAGTACTCCTCAAAAGACGGCAGAGGCTGACCCCAGAAGAGG
AGTAGGGTCTCCTCCTGGGAGGAAGAAGACCACAGTCTCCATGCCACGAAGCAGGAAGGGAGATGCAGCATCCCAGTTTTTGGTCTTCTG
TCAAAAACACAGGGATGAGGTGGTAGCTGAGCACCCAGATGCTTCAGGTGAGGAGATTGAAGAGCTGCTCAGGTCACAGTGGAGTCTGCT
GAGTGAGAAGCAGAGAGCACGCTACAACACCAAGTTTGCCCTGGTGGCCCCTGTCCAGGCTGAAGAAGACTCTGGTAATGTAAATGGGAA
AAAAAGAAACCACACAAAGAGGATACAGGACCCTACAGAAGATGCTGAAGCTGAGGACACACCCAGGAAAAGACTCAGGACGGACAAGCA
CAGTCTTCGGAAGAGAGACACAATCACTGACAAAACGGCCAGAACAAGCTCTTACAAGGCCATGGAGGCAGCCTCCTCGCTCAAGAGCCA
GGCAGCAACGAAAAATCTGTCTGATGCATGTAAACCACTGAAGAAGCGAAATCGGGCTTCCACGGCAGCATCTTCAGCTCTTGGGTTTAG
CAAAAGTTCATCTCCTTCTGCATCCTTAACTGAGAATGAGGTCTCGGACAGCCCGGGAGACGAGCCCTCGGAGTCCCCATACGAAAGTGC
AGACGAAACACAAACTGAAGTATCTGTCTCATCCAAAAAGTCTGAGCGAGGAGTGACTGCCAAAAAGGAGTATGTGTGCCAGCTGTGTGA
GAAGCCGGGCAGCCTCCTGCTCTGTGAAGGACCCTGCTGCGGAGCTTTCCACCTCGCCTGCCTTGGGCTTTCCCGGAGGCCAGAAGGGAG
GTTCACCTGCAGCGAGTGTGCCTCAGGGATTCACTCATGTTTCGTGTGTAAAGAGAGCAAGACAGATGTTAAGCGCTGTGTGGTAACTCA
GTGTGGAAAATTTTACCATGAGGCTTGTGTGAAAAAATACCCTCTGACTGTATTTGAGAGCCGAGGTTTCCGCTGCCCCCTCCACAGCTG
TGTGAGCTGCCATGCTTCCAACCCTTCAAACCCAAGGCCGTCAAAAGGTAAAATGATGCGGTGTGTCCGCTGCCCCGTTGCCTATCACAG
CGGGGATGCTTGTCTGGCAGCAGGATGCTCAGTGATCGCCTCCAACAGCATCATCTGCACTGCCCACTTCACTGCTCGGAAGGGGAAGCG
ACACCACGCCCACGTCAACGTGAGCTGGTGCTTCGTGTGCTCCAAAGGGGGGAGCCTTCTGTGCTGTGAGTCCTGCCCAGCGGCCTTCCA
CCCTGACTGCCTGAACATCGAGATGCCTGACGGCAGCTGGTTCTGCAATGACTGCAGGGCTGGGAAGAAGCTGCACTTCCAGGATATCAT
TTGGGTGAAACTTGGGAACTACAGATGGTGGCCGGCAGAAGTTTGCCATCCCAAAAATGTTCCCCCAAATATTCAGAAAATGAAGCACGA
GATTGGAGAATTCCCTGTGTTTTTCTTTGGGTCTAAAGATTATTACTGGACGCATCAGGCGCGAGTGTTCCCGTACATGGAGGGGGACCG
GGGCAGCCGCTACCAGGGGGTCAGAGGGATCGGAAGAGTCTTCAAAAACGGTCAAAAGGCTGAGTTTCAAATTCTGGATAATGTAGACTC
AACGGGAGAGTTGATAGTGAGATTACCCAAAGAAATAACAATTTCAGGCAGTTTCCAGGGCTTCCACCATCAGAAAATCAAGATATCGGA
GAACCGGATATCCCAGCAGTATCTGGCTACCCTTGAAAACAGGAAGCTGAAGAGGGAACTACCCTTTTCATTCCGATCAATTAATACGAG
AGAAAACCTGTATCTGGTGACAGAAACTCTGGAGACGGTAAAGGAGGAAACCCTGAAAAGCGACCGGCAATATAAATTTTGGAGCCAGAT
CTCTCAGGGCCATCTCAGCTATAAACACAAGGGCCAAAGGGAAGTGACCATCCCCCCAAATCGGGTCCTGAGCTATCGAGTAAAGCAGCT
TGTCTTCCCCAACAAGGAGACGATGAAGAAGGATGGTGCTTCATCCTGTTTAGGAAAGTCTTTGGGTTCGGAGGATTCCAGAAACATGAA
GGAGAAGTTGGAGGACATGGAGAGTGTCCTCAAGGACCTGACAGAGGAGAAGAGAAAAGATGTGCTAAACTCCCTCGCTAAGTGCCTCGG
CAAGGAGGATATTCGGCAGGATCTAGAGCAAAGAGTATCTGAGGTCCTGATTTCCGGGGAGCTACACATGGAGGACCCAGACAAGCCTCT
CCTAAGCAGCCTTTTTAATGCTGCTGGGGTCTTGGTAGAAGCGCGTGCAAAAGCCATTCTGGACTTCCTGGATGCCCTGCTAGAGCTGTC
TGAAGAGCAGCAGTTTGTGGCTGAGGCCCTGGAGAAGGGGACCCTTCCTCTGTTGAAGGACCAGGTGAAATCTGTCATGGAGCAGAACTG
GGATGAGCTGGCCAGCAGTCCTCCTGACATGGACTATGACCCTGAGGCACGAATTCTCTGTGCGCTGTATGTTGTTGTCTCTATCCTGCT
GGAGCTGGCTGAGGGGCCTACCTCTGTCTCTTCCTAACTACAAAAGCCCTTTCTCCCCACAAGCCTCTGGGTTTTCCCTTTACCAGTCTG
TCCTCACTGCCATCGCCACTACCATCCTGTCACCAGTGGGACCTCTTTAAAACAAGCAGCCAACCATTCTTTGATGTATCCCATTCGCTC

>99189_99189_7_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000382891_GSDMB_chr17_38068750_ENST00000309481_length(amino acids)=1288AA_BP=963
MGWMEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEGVMQKFNGHDALPFIPADKLKDLTSRVF
NGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNGSPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDS
LLEQGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFF
GDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNP
QVAKEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGKSTPQKTAEADPRRGVGSPPGRKKTTVS
MPRSRKGDAASQFLVFCQKHRDEVVAEHPDASGEEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTE
DAEAEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKRNRASTAASSALGFSKSSSPSASLTENE
VSDSPGDEPSESPYESADETQTEVSVSSKKSERGVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSC
FVCKESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKGKMMRCVRCPVAYHSGDACLAAGCSVIA
SNSIICTAHFTARKGKRHHAHVNVSWCFVCSKGGSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAE
VCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKNGQKAEFQILDNVDSTGELIVRLPKEIT
ISGSFQGFHHQKIKISENRISQQYLATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWSQISQGHLSYKHKGQR
EVTIPPNRVLSYRVKQLVFPNKETMKKDGASSCLGKSLGSEDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVS
EVLISGELHMEDPDKPLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQNWDELASSPPDMDYD

--------------------------------------------------------------
>99189_99189_8_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000382891_GSDMB_chr17_38068750_ENST00000360317_length(transcript)=4253nt_BP=3020nt
TGGTCTTGAACTCCTGACCTTGTGATCCGCTCGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGTGCCTGTCCTAGAA
CCACTGGTAACTCTTAACTGTGTTCTAAGAACGGAAGCATCTGGGCTGGATGGAATTTAGCATCAAGCAGAGTCCCCTTTCTGTTCAGAG
TGTTGTAAAGTGCATAAAGATGAAGCAGGCACCAGAAATCCTCGGCAGTGCCAACGGGAAGACTCCGAGCTGCGAGGTGAACCGCGAGTG
TTCTGTGTTCCTCAGCAAAGCCCAGCTCTCCAGTAGCCTGCAGGAGGGGGTCATGCAGAAGTTTAACGGCCACGACGCCCTGCCCTTTAT
TCCAGCCGACAAGCTGAAAGATCTTACTTCCCGGGTGTTTAATGGAGAACCCGGCGCACACGATGCCAAACTGCGTTTTGAGTCCCAGGA
AATGAAAGGGATTGGGACACCCCCTAACACTACCCCTATCAAAAATGGCTCTCCAGAAATTAAGCTGAAAATCACCAAAACATACATGAA
TGGGAAGCCTCTCTTTGAATCTTCCATTTGTGGTGACAGTGCTGCTGATGTGTCTCAGTCAGAAGAAAATGGACAAAAACCAGAAAACAA
GGCGAGAAGGAACAGGAAGAGGAGCATAAAATATGACTCCTTGCTGGAGCAGGGCCTTGTCGAAGCAGCTCTTGTGTCTAAGATCTCAAG
TCCTTCAGATAAAAAGATTCCAGCTAAGAAAGAGTCTTGTCCAAACACTGGAAGAGACAAAGACCACCTGTTGAAATACAACGTTGGTGA
TTTGGTGTGGTCCAAAGTGTCGGGTTACCCTTGGTGGCCTTGCATGGTTTCTGCAGATCCACTCCTTCACAGCTATACCAAACTTAAAGG
TCAGAAAAAGAGTGCACGCCAGTATCACGTACAGTTCTTTGGTGACGCCCCAGAAAGAGCTTGGATATTTGAGAAGAGCCTCGTAGCTTT
TGAAGGAGAAGGACAGTTTGAAAAATTATGCCAGGAAAGTGCCAAGCAGGCACCCACGAAAGCTGAGAAAATTAAGCTATTGAAACCAAT
TTCAGGGAAATTGAGGGCCCAGTGGGAAATGGGCATTGTTCAAGCAGAAGAAGCTGCAAGCATGTCAGTGGAGGAGCGGAAAGCCAAGTT
CACCTTTCTCTATGTGGGGGACCAGCTTCATCTCAACCCTCAAGTAGCCAAGGAGGCTGGCATTGCTGCAGAGTCTTTGGGAGAAATGGC
AGAATCCTCAGGAGTCAGTGAAGAAGCTGCTGAAAACCCCAAGTCTGTGAGAGAAGAGTGCATTCCCATGAAGAGAAGGCGGAGGGCCAA
ACTGTGTAGCTCTGCAGAGACCCTGGAGAGTCACCCCGACATAGGGAAGAGTACTCCTCAAAAGACGGCAGAGGCTGACCCCAGAAGAGG
AGTAGGGTCTCCTCCTGGGAGGAAGAAGACCACAGTCTCCATGCCACGAAGCAGGAAGGGAGATGCAGCATCCCAGTTTTTGGTCTTCTG
TCAAAAACACAGGGATGAGGTGGTAGCTGAGCACCCAGATGCTTCAGGTGAGGAGATTGAAGAGCTGCTCAGGTCACAGTGGAGTCTGCT
GAGTGAGAAGCAGAGAGCACGCTACAACACCAAGTTTGCCCTGGTGGCCCCTGTCCAGGCTGAAGAAGACTCTGGTAATGTAAATGGGAA
AAAAAGAAACCACACAAAGAGGATACAGGACCCTACAGAAGATGCTGAAGCTGAGGACACACCCAGGAAAAGACTCAGGACGGACAAGCA
CAGTCTTCGGAAGAGAGACACAATCACTGACAAAACGGCCAGAACAAGCTCTTACAAGGCCATGGAGGCAGCCTCCTCGCTCAAGAGCCA
GGCAGCAACGAAAAATCTGTCTGATGCATGTAAACCACTGAAGAAGCGAAATCGGGCTTCCACGGCAGCATCTTCAGCTCTTGGGTTTAG
CAAAAGTTCATCTCCTTCTGCATCCTTAACTGAGAATGAGGTCTCGGACAGCCCGGGAGACGAGCCCTCGGAGTCCCCATACGAAAGTGC
AGACGAAACACAAACTGAAGTATCTGTCTCATCCAAAAAGTCTGAGCGAGGAGTGACTGCCAAAAAGGAGTATGTGTGCCAGCTGTGTGA
GAAGCCGGGCAGCCTCCTGCTCTGTGAAGGACCCTGCTGCGGAGCTTTCCACCTCGCCTGCCTTGGGCTTTCCCGGAGGCCAGAAGGGAG
GTTCACCTGCAGCGAGTGTGCCTCAGGGATTCACTCATGTTTCGTGTGTAAAGAGAGCAAGACAGATGTTAAGCGCTGTGTGGTAACTCA
GTGTGGAAAATTTTACCATGAGGCTTGTGTGAAAAAATACCCTCTGACTGTATTTGAGAGCCGAGGTTTCCGCTGCCCCCTCCACAGCTG
TGTGAGCTGCCATGCTTCCAACCCTTCAAACCCAAGGCCGTCAAAAGGTAAAATGATGCGGTGTGTCCGCTGCCCCGTTGCCTATCACAG
CGGGGATGCTTGTCTGGCAGCAGGATGCTCAGTGATCGCCTCCAACAGCATCATCTGCACTGCCCACTTCACTGCTCGGAAGGGGAAGCG
ACACCACGCCCACGTCAACGTGAGCTGGTGCTTCGTGTGCTCCAAAGGGGGGAGCCTTCTGTGCTGTGAGTCCTGCCCAGCGGCCTTCCA
CCCTGACTGCCTGAACATCGAGATGCCTGACGGCAGCTGGTTCTGCAATGACTGCAGGGCTGGGAAGAAGCTGCACTTCCAGGATATCAT
TTGGGTGAAACTTGGGAACTACAGATGGTGGCCGGCAGAAGTTTGCCATCCCAAAAATGTTCCCCCAAATATTCAGAAAATGAAGCACGA
GATTGGAGAATTCCCTGTGTTTTTCTTTGGGTCTAAAGATTATTACTGGACGCATCAGGCGCGAGTGTTCCCGTACATGGAGGGGGACCG
GGGCAGCCGCTACCAGGGGGTCAGAGGGATCGGAAGAGTCTTCAAAAACGGTCAAAAGGCTGAGTTTCAAATTCTGGATAATGTAGACTC
AACGGGAGAGTTGATAGTGAGATTACCCAAAGAAATAACAATTTCAGGCAGTTTCCAGGGCTTCCACCATCAGAAAATCAAGATATCGGA
GAACCGGATATCCCAGCAGTATCTGGCTACCCTTGAAAACAGGAAGCTGAAGAGGGAACTACCCTTTTCATTCCGATCAATTAATACGAG
AGAAAACCTGTATCTGGTGACAGAAACTCTGGAGACGGTAAAGGAGGAAACCCTGAAAAGCGACCGGCAATATAAATTTTGGAGCCAGAT
CTCTCAGGGCCATCTCAGCTATAAACACAAGGGCCAAAGGGAAGTGACCATCCCCCCAAATCGGGTCCTGAGCTATCGAGTAAAGCAGCT
TGTCTTCCCCAACAAGGAGACGATGAATATTCATTTCAGGGGCAAAACAAAATCCTTTCCAGAAGAGAAGGATGGTGCTTCATCCTGTTT
AGGAAAGTCTTTGGGTTCGGAGGATTCCAGAAACATGAAGGAGAAGTTGGAGGACATGGAGAGTGTCCTCAAGGACCTGACAGAGGAGAA
GAGAAAAGATGTGCTAAACTCCCTCGCTAAGTGCCTCGGCAAGGAGGATATTCGGCAGGATCTAGAGCAAAGAGTATCTGAGGTCCTGAT
TTCCGGGGAGCTACACATGGAGGACCCAGACAAGCCTCTCCTAAGCAGCCTTTTTAATGCTGCTGGGGTCTTGGTAGAAGCGCGTGCAAA
AGCCATTCTGGACTTCCTGGATGCCCTGCTAGAGCTGTCTGAAGAGCAGCAGTTTGTGGCTGAGGCCCTGGAGAAGGGGACCCTTCCTCT
GTTGAAGGACCAGGTGAAATCTGTCATGGAGCAGAACTGGGATGAGCTGGCCAGCAGTCCTCCTGACATGGACTATGACCCTGAGGCACG
AATTCTCTGTGCGCTGTATGTTGTTGTCTCTATCCTGCTGGAGCTGGCTGAGGGGCCTACCTCTGTCTCTTCCTAACTACAAAAGCCCTT
TCTCCCCACAAGCCTCTGGGTTTTCCCTTTACCAGTCTGTCCTCACTGCCATCGCCACTACCATCCTGTCACCAGTGGGACCTCTTTAAA
ACAAGCAGCCAACCATTCTTTGATGTATCCCATTCGCTCCATGTTAACATCCAAAACCAGCCTGGATTTCATACATGGACTTCTGATTAA

>99189_99189_8_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000382891_GSDMB_chr17_38068750_ENST00000360317_length(amino acids)=1301AA_BP=963
MGWMEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEGVMQKFNGHDALPFIPADKLKDLTSRVF
NGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNGSPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDS
LLEQGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFF
GDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNP
QVAKEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGKSTPQKTAEADPRRGVGSPPGRKKTTVS
MPRSRKGDAASQFLVFCQKHRDEVVAEHPDASGEEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTE
DAEAEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKRNRASTAASSALGFSKSSSPSASLTENE
VSDSPGDEPSESPYESADETQTEVSVSSKKSERGVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSC
FVCKESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKGKMMRCVRCPVAYHSGDACLAAGCSVIA
SNSIICTAHFTARKGKRHHAHVNVSWCFVCSKGGSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAE
VCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKNGQKAEFQILDNVDSTGELIVRLPKEIT
ISGSFQGFHHQKIKISENRISQQYLATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWSQISQGHLSYKHKGQR
EVTIPPNRVLSYRVKQLVFPNKETMNIHFRGKTKSFPEEKDGASSCLGKSLGSEDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLG
KEDIRQDLEQRVSEVLISGELHMEDPDKPLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQNW

--------------------------------------------------------------
>99189_99189_9_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000382891_GSDMB_chr17_38068750_ENST00000394175_length(transcript)=4187nt_BP=3020nt
TGGTCTTGAACTCCTGACCTTGTGATCCGCTCGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGTGCCTGTCCTAGAA
CCACTGGTAACTCTTAACTGTGTTCTAAGAACGGAAGCATCTGGGCTGGATGGAATTTAGCATCAAGCAGAGTCCCCTTTCTGTTCAGAG
TGTTGTAAAGTGCATAAAGATGAAGCAGGCACCAGAAATCCTCGGCAGTGCCAACGGGAAGACTCCGAGCTGCGAGGTGAACCGCGAGTG
TTCTGTGTTCCTCAGCAAAGCCCAGCTCTCCAGTAGCCTGCAGGAGGGGGTCATGCAGAAGTTTAACGGCCACGACGCCCTGCCCTTTAT
TCCAGCCGACAAGCTGAAAGATCTTACTTCCCGGGTGTTTAATGGAGAACCCGGCGCACACGATGCCAAACTGCGTTTTGAGTCCCAGGA
AATGAAAGGGATTGGGACACCCCCTAACACTACCCCTATCAAAAATGGCTCTCCAGAAATTAAGCTGAAAATCACCAAAACATACATGAA
TGGGAAGCCTCTCTTTGAATCTTCCATTTGTGGTGACAGTGCTGCTGATGTGTCTCAGTCAGAAGAAAATGGACAAAAACCAGAAAACAA
GGCGAGAAGGAACAGGAAGAGGAGCATAAAATATGACTCCTTGCTGGAGCAGGGCCTTGTCGAAGCAGCTCTTGTGTCTAAGATCTCAAG
TCCTTCAGATAAAAAGATTCCAGCTAAGAAAGAGTCTTGTCCAAACACTGGAAGAGACAAAGACCACCTGTTGAAATACAACGTTGGTGA
TTTGGTGTGGTCCAAAGTGTCGGGTTACCCTTGGTGGCCTTGCATGGTTTCTGCAGATCCACTCCTTCACAGCTATACCAAACTTAAAGG
TCAGAAAAAGAGTGCACGCCAGTATCACGTACAGTTCTTTGGTGACGCCCCAGAAAGAGCTTGGATATTTGAGAAGAGCCTCGTAGCTTT
TGAAGGAGAAGGACAGTTTGAAAAATTATGCCAGGAAAGTGCCAAGCAGGCACCCACGAAAGCTGAGAAAATTAAGCTATTGAAACCAAT
TTCAGGGAAATTGAGGGCCCAGTGGGAAATGGGCATTGTTCAAGCAGAAGAAGCTGCAAGCATGTCAGTGGAGGAGCGGAAAGCCAAGTT
CACCTTTCTCTATGTGGGGGACCAGCTTCATCTCAACCCTCAAGTAGCCAAGGAGGCTGGCATTGCTGCAGAGTCTTTGGGAGAAATGGC
AGAATCCTCAGGAGTCAGTGAAGAAGCTGCTGAAAACCCCAAGTCTGTGAGAGAAGAGTGCATTCCCATGAAGAGAAGGCGGAGGGCCAA
ACTGTGTAGCTCTGCAGAGACCCTGGAGAGTCACCCCGACATAGGGAAGAGTACTCCTCAAAAGACGGCAGAGGCTGACCCCAGAAGAGG
AGTAGGGTCTCCTCCTGGGAGGAAGAAGACCACAGTCTCCATGCCACGAAGCAGGAAGGGAGATGCAGCATCCCAGTTTTTGGTCTTCTG
TCAAAAACACAGGGATGAGGTGGTAGCTGAGCACCCAGATGCTTCAGGTGAGGAGATTGAAGAGCTGCTCAGGTCACAGTGGAGTCTGCT
GAGTGAGAAGCAGAGAGCACGCTACAACACCAAGTTTGCCCTGGTGGCCCCTGTCCAGGCTGAAGAAGACTCTGGTAATGTAAATGGGAA
AAAAAGAAACCACACAAAGAGGATACAGGACCCTACAGAAGATGCTGAAGCTGAGGACACACCCAGGAAAAGACTCAGGACGGACAAGCA
CAGTCTTCGGAAGAGAGACACAATCACTGACAAAACGGCCAGAACAAGCTCTTACAAGGCCATGGAGGCAGCCTCCTCGCTCAAGAGCCA
GGCAGCAACGAAAAATCTGTCTGATGCATGTAAACCACTGAAGAAGCGAAATCGGGCTTCCACGGCAGCATCTTCAGCTCTTGGGTTTAG
CAAAAGTTCATCTCCTTCTGCATCCTTAACTGAGAATGAGGTCTCGGACAGCCCGGGAGACGAGCCCTCGGAGTCCCCATACGAAAGTGC
AGACGAAACACAAACTGAAGTATCTGTCTCATCCAAAAAGTCTGAGCGAGGAGTGACTGCCAAAAAGGAGTATGTGTGCCAGCTGTGTGA
GAAGCCGGGCAGCCTCCTGCTCTGTGAAGGACCCTGCTGCGGAGCTTTCCACCTCGCCTGCCTTGGGCTTTCCCGGAGGCCAGAAGGGAG
GTTCACCTGCAGCGAGTGTGCCTCAGGGATTCACTCATGTTTCGTGTGTAAAGAGAGCAAGACAGATGTTAAGCGCTGTGTGGTAACTCA
GTGTGGAAAATTTTACCATGAGGCTTGTGTGAAAAAATACCCTCTGACTGTATTTGAGAGCCGAGGTTTCCGCTGCCCCCTCCACAGCTG
TGTGAGCTGCCATGCTTCCAACCCTTCAAACCCAAGGCCGTCAAAAGGTAAAATGATGCGGTGTGTCCGCTGCCCCGTTGCCTATCACAG
CGGGGATGCTTGTCTGGCAGCAGGATGCTCAGTGATCGCCTCCAACAGCATCATCTGCACTGCCCACTTCACTGCTCGGAAGGGGAAGCG
ACACCACGCCCACGTCAACGTGAGCTGGTGCTTCGTGTGCTCCAAAGGGGGGAGCCTTCTGTGCTGTGAGTCCTGCCCAGCGGCCTTCCA
CCCTGACTGCCTGAACATCGAGATGCCTGACGGCAGCTGGTTCTGCAATGACTGCAGGGCTGGGAAGAAGCTGCACTTCCAGGATATCAT
TTGGGTGAAACTTGGGAACTACAGATGGTGGCCGGCAGAAGTTTGCCATCCCAAAAATGTTCCCCCAAATATTCAGAAAATGAAGCACGA
GATTGGAGAATTCCCTGTGTTTTTCTTTGGGTCTAAAGATTATTACTGGACGCATCAGGCGCGAGTGTTCCCGTACATGGAGGGGGACCG
GGGCAGCCGCTACCAGGGGGTCAGAGGGATCGGAAGAGTCTTCAAAAACGGTCAAAAGGCTGAGTTTCAAATTCTGGATAATGTAGACTC
AACGGGAGAGTTGATAGTGAGATTACCCAAAGAAATAACAATTTCAGGCAGTTTCCAGGGCTTCCACCATCAGAAAATCAAGATATCGGA
GAACCGGATATCCCAGCAGTATCTGGCTACCCTTGAAAACAGGAAGCTGAAGAGGGAACTACCCTTTTCATTCCGATCAATTAATACGAG
AGAAAACCTGTATCTGGTGACAGAAACTCTGGAGACGGTAAAGGAGGAAACCCTGAAAAGCGACCGGCAATATAAATTTTGGAGCCAGAT
CTCTCAGGGCCATCTCAGCTATAAACACAAGGGCCAAAGGGAAGTGACCATCCCCCCAAATCGGGTCCTGAGCTATCGAGTAAAGCAGCT
TGTCTTCCCCAACAAGGAGACGATGAGAAAGTCTTTGGGTTCGGAGGATTCCAGAAACATGAAGGAGAAGTTGGAGGACATGGAGAGTGT
CCTCAAGGACCTGACAGAGGAGAAGAGAAAAGATGTGCTAAACTCCCTCGCTAAGTGCCTCGGCAAGGAGGATATTCGGCAGGATCTAGA
GCAAAGAGTATCTGAGGTCCTGATTTCCGGGGAGCTACACATGGAGGACCCAGACAAGCCTCTCCTAAGCAGCCTTTTTAATGCTGCTGG
GGTCTTGGTAGAAGCGCGTGCAAAAGCCATTCTGGACTTCCTGGATGCCCTGCTAGAGCTGTCTGAAGAGCAGCAGTTTGTGGCTGAGGC
CCTGGAGAAGGGGACCCTTCCTCTGTTGAAGGACCAGGTGAAATCTGTCATGGAGCAGAACTGGGATGAGCTGGCCAGCAGTCCTCCTGA
CATGGACTATGACCCTGAGGCACGAATTCTCTGTGCGCTGTATGTTGTTGTCTCTATCCTGCTGGAGCTGGCTGAGGGGCCTACCTCTGT
CTCTTCCTAACTACAAAAGCCCTTTCTCCCCACAAGCCTCTGGGTTTTCCCTTTACCAGTCTGTCCTCACTGCCATCGCCACTACCATCC
TGTCACCAGTGGGACCTCTTTAAAACAAGCAGCCAACCATTCTTTGATGTATCCCATTCGCTCCATGTTAACATCCAAAACCAGCCTGGA

>99189_99189_9_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000382891_GSDMB_chr17_38068750_ENST00000394175_length(amino acids)=1279AA_BP=963
MGWMEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEGVMQKFNGHDALPFIPADKLKDLTSRVF
NGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNGSPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDS
LLEQGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFF
GDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNP
QVAKEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGKSTPQKTAEADPRRGVGSPPGRKKTTVS
MPRSRKGDAASQFLVFCQKHRDEVVAEHPDASGEEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTE
DAEAEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKRNRASTAASSALGFSKSSSPSASLTENE
VSDSPGDEPSESPYESADETQTEVSVSSKKSERGVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSC
FVCKESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKGKMMRCVRCPVAYHSGDACLAAGCSVIA
SNSIICTAHFTARKGKRHHAHVNVSWCFVCSKGGSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAE
VCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKNGQKAEFQILDNVDSTGELIVRLPKEIT
ISGSFQGFHHQKIKISENRISQQYLATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWSQISQGHLSYKHKGQR
EVTIPPNRVLSYRVKQLVFPNKETMRKSLGSEDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELH
MEDPDKPLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQNWDELASSPPDMDYDPEARILCAL

--------------------------------------------------------------
>99189_99189_10_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000382891_GSDMB_chr17_38068750_ENST00000394179_length(transcript)=4236nt_BP=3020nt
TGGTCTTGAACTCCTGACCTTGTGATCCGCTCGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGTGCCTGTCCTAGAA
CCACTGGTAACTCTTAACTGTGTTCTAAGAACGGAAGCATCTGGGCTGGATGGAATTTAGCATCAAGCAGAGTCCCCTTTCTGTTCAGAG
TGTTGTAAAGTGCATAAAGATGAAGCAGGCACCAGAAATCCTCGGCAGTGCCAACGGGAAGACTCCGAGCTGCGAGGTGAACCGCGAGTG
TTCTGTGTTCCTCAGCAAAGCCCAGCTCTCCAGTAGCCTGCAGGAGGGGGTCATGCAGAAGTTTAACGGCCACGACGCCCTGCCCTTTAT
TCCAGCCGACAAGCTGAAAGATCTTACTTCCCGGGTGTTTAATGGAGAACCCGGCGCACACGATGCCAAACTGCGTTTTGAGTCCCAGGA
AATGAAAGGGATTGGGACACCCCCTAACACTACCCCTATCAAAAATGGCTCTCCAGAAATTAAGCTGAAAATCACCAAAACATACATGAA
TGGGAAGCCTCTCTTTGAATCTTCCATTTGTGGTGACAGTGCTGCTGATGTGTCTCAGTCAGAAGAAAATGGACAAAAACCAGAAAACAA
GGCGAGAAGGAACAGGAAGAGGAGCATAAAATATGACTCCTTGCTGGAGCAGGGCCTTGTCGAAGCAGCTCTTGTGTCTAAGATCTCAAG
TCCTTCAGATAAAAAGATTCCAGCTAAGAAAGAGTCTTGTCCAAACACTGGAAGAGACAAAGACCACCTGTTGAAATACAACGTTGGTGA
TTTGGTGTGGTCCAAAGTGTCGGGTTACCCTTGGTGGCCTTGCATGGTTTCTGCAGATCCACTCCTTCACAGCTATACCAAACTTAAAGG
TCAGAAAAAGAGTGCACGCCAGTATCACGTACAGTTCTTTGGTGACGCCCCAGAAAGAGCTTGGATATTTGAGAAGAGCCTCGTAGCTTT
TGAAGGAGAAGGACAGTTTGAAAAATTATGCCAGGAAAGTGCCAAGCAGGCACCCACGAAAGCTGAGAAAATTAAGCTATTGAAACCAAT
TTCAGGGAAATTGAGGGCCCAGTGGGAAATGGGCATTGTTCAAGCAGAAGAAGCTGCAAGCATGTCAGTGGAGGAGCGGAAAGCCAAGTT
CACCTTTCTCTATGTGGGGGACCAGCTTCATCTCAACCCTCAAGTAGCCAAGGAGGCTGGCATTGCTGCAGAGTCTTTGGGAGAAATGGC
AGAATCCTCAGGAGTCAGTGAAGAAGCTGCTGAAAACCCCAAGTCTGTGAGAGAAGAGTGCATTCCCATGAAGAGAAGGCGGAGGGCCAA
ACTGTGTAGCTCTGCAGAGACCCTGGAGAGTCACCCCGACATAGGGAAGAGTACTCCTCAAAAGACGGCAGAGGCTGACCCCAGAAGAGG
AGTAGGGTCTCCTCCTGGGAGGAAGAAGACCACAGTCTCCATGCCACGAAGCAGGAAGGGAGATGCAGCATCCCAGTTTTTGGTCTTCTG
TCAAAAACACAGGGATGAGGTGGTAGCTGAGCACCCAGATGCTTCAGGTGAGGAGATTGAAGAGCTGCTCAGGTCACAGTGGAGTCTGCT
GAGTGAGAAGCAGAGAGCACGCTACAACACCAAGTTTGCCCTGGTGGCCCCTGTCCAGGCTGAAGAAGACTCTGGTAATGTAAATGGGAA
AAAAAGAAACCACACAAAGAGGATACAGGACCCTACAGAAGATGCTGAAGCTGAGGACACACCCAGGAAAAGACTCAGGACGGACAAGCA
CAGTCTTCGGAAGAGAGACACAATCACTGACAAAACGGCCAGAACAAGCTCTTACAAGGCCATGGAGGCAGCCTCCTCGCTCAAGAGCCA
GGCAGCAACGAAAAATCTGTCTGATGCATGTAAACCACTGAAGAAGCGAAATCGGGCTTCCACGGCAGCATCTTCAGCTCTTGGGTTTAG
CAAAAGTTCATCTCCTTCTGCATCCTTAACTGAGAATGAGGTCTCGGACAGCCCGGGAGACGAGCCCTCGGAGTCCCCATACGAAAGTGC
AGACGAAACACAAACTGAAGTATCTGTCTCATCCAAAAAGTCTGAGCGAGGAGTGACTGCCAAAAAGGAGTATGTGTGCCAGCTGTGTGA
GAAGCCGGGCAGCCTCCTGCTCTGTGAAGGACCCTGCTGCGGAGCTTTCCACCTCGCCTGCCTTGGGCTTTCCCGGAGGCCAGAAGGGAG
GTTCACCTGCAGCGAGTGTGCCTCAGGGATTCACTCATGTTTCGTGTGTAAAGAGAGCAAGACAGATGTTAAGCGCTGTGTGGTAACTCA
GTGTGGAAAATTTTACCATGAGGCTTGTGTGAAAAAATACCCTCTGACTGTATTTGAGAGCCGAGGTTTCCGCTGCCCCCTCCACAGCTG
TGTGAGCTGCCATGCTTCCAACCCTTCAAACCCAAGGCCGTCAAAAGGTAAAATGATGCGGTGTGTCCGCTGCCCCGTTGCCTATCACAG
CGGGGATGCTTGTCTGGCAGCAGGATGCTCAGTGATCGCCTCCAACAGCATCATCTGCACTGCCCACTTCACTGCTCGGAAGGGGAAGCG
ACACCACGCCCACGTCAACGTGAGCTGGTGCTTCGTGTGCTCCAAAGGGGGGAGCCTTCTGTGCTGTGAGTCCTGCCCAGCGGCCTTCCA
CCCTGACTGCCTGAACATCGAGATGCCTGACGGCAGCTGGTTCTGCAATGACTGCAGGGCTGGGAAGAAGCTGCACTTCCAGGATATCAT
TTGGGTGAAACTTGGGAACTACAGATGGTGGCCGGCAGAAGTTTGCCATCCCAAAAATGTTCCCCCAAATATTCAGAAAATGAAGCACGA
GATTGGAGAATTCCCTGTGTTTTTCTTTGGGTCTAAAGATTATTACTGGACGCATCAGGCGCGAGTGTTCCCGTACATGGAGGGGGACCG
GGGCAGCCGCTACCAGGGGGTCAGAGGGATCGGAAGAGTCTTCAAAAACGGTCAAAAGGCTGAGTTTCAAATTCTGGATAATGTAGACTC
AACGGGAGAGTTGATAGTGAGATTACCCAAAGAAATAACAATTTCAGGCAGTTTCCAGGGCTTCCACCATCAGAAAATCAAGATATCGGA
GAACCGGATATCCCAGCAGTATCTGGCTACCCTTGAAAACAGGAAGCTGAAGAGGGAACTACCCTTTTCATTCCGATCAATTAATACGAG
AGAAAACCTGTATCTGGTGACAGAAACTCTGGAGACGGTAAAGGAGGAAACCCTGAAAAGCGACCGGCAATATAAATTTTGGAGCCAGAT
CTCTCAGGGCCATCTCAGCTATAAACACAAGGGCCAAAGGGAAGTGACCATCCCCCCAAATCGGGTCCTGAGCTATCGAGTAAAGCAGCT
TGTCTTCCCCAACAAGGAGACGATGAGTGCTGGTTTAGATATTCATTTCAGGGGCAAAACAAAATCCTTTCCAGAAGGAAAGTCTTTGGG
TTCGGAGGATTCCAGAAACATGAAGGAGAAGTTGGAGGACATGGAGAGTGTCCTCAAGGACCTGACAGAGGAGAAGAGAAAAGATGTGCT
AAACTCCCTCGCTAAGTGCCTCGGCAAGGAGGATATTCGGCAGGATCTAGAGCAAAGAGTATCTGAGGTCCTGATTTCCGGGGAGCTACA
CATGGAGGACCCAGACAAGCCTCTCCTAAGCAGCCTTTTTAATGCTGCTGGGGTCTTGGTAGAAGCGCGTGCAAAAGCCATTCTGGACTT
CCTGGATGCCCTGCTAGAGCTGTCTGAAGAGCAGCAGTTTGTGGCTGAGGCCCTGGAGAAGGGGACCCTTCCTCTGTTGAAGGACCAGGT
GAAATCTGTCATGGAGCAGAACTGGGATGAGCTGGCCAGCAGTCCTCCTGACATGGACTATGACCCTGAGGCACGAATTCTCTGTGCGCT
GTATGTTGTTGTCTCTATCCTGCTGGAGCTGGCTGAGGGGCCTACCTCTGTCTCTTCCTAACTACAAAAGCCCTTTCTCCCCACAAGCCT
CTGGGTTTTCCCTTTACCAGTCTGTCCTCACTGCCATCGCCACTACCATCCTGTCACCAGTGGGACCTCTTTAAAACAAGCAGCCAACCA
TTCTTTGATGTATCCCATTCGCTCCATGTTAACATCCAAAACCAGCCTGGATTTCATACATGGACTTCTGATTAAAAGTGGCAGGTTGTG

>99189_99189_10_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000382891_GSDMB_chr17_38068750_ENST00000394179_length(amino acids)=1296AA_BP=963
MGWMEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEGVMQKFNGHDALPFIPADKLKDLTSRVF
NGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNGSPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDS
LLEQGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFF
GDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNP
QVAKEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGKSTPQKTAEADPRRGVGSPPGRKKTTVS
MPRSRKGDAASQFLVFCQKHRDEVVAEHPDASGEEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTE
DAEAEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKRNRASTAASSALGFSKSSSPSASLTENE
VSDSPGDEPSESPYESADETQTEVSVSSKKSERGVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSC
FVCKESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKGKMMRCVRCPVAYHSGDACLAAGCSVIA
SNSIICTAHFTARKGKRHHAHVNVSWCFVCSKGGSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAE
VCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKNGQKAEFQILDNVDSTGELIVRLPKEIT
ISGSFQGFHHQKIKISENRISQQYLATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWSQISQGHLSYKHKGQR
EVTIPPNRVLSYRVKQLVFPNKETMSAGLDIHFRGKTKSFPEGKSLGSEDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIR
QDLEQRVSEVLISGELHMEDPDKPLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQNWDELAS

--------------------------------------------------------------
>99189_99189_11_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000382891_GSDMB_chr17_38068750_ENST00000418519_length(transcript)=4251nt_BP=3020nt
TGGTCTTGAACTCCTGACCTTGTGATCCGCTCGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGTGCCTGTCCTAGAA
CCACTGGTAACTCTTAACTGTGTTCTAAGAACGGAAGCATCTGGGCTGGATGGAATTTAGCATCAAGCAGAGTCCCCTTTCTGTTCAGAG
TGTTGTAAAGTGCATAAAGATGAAGCAGGCACCAGAAATCCTCGGCAGTGCCAACGGGAAGACTCCGAGCTGCGAGGTGAACCGCGAGTG
TTCTGTGTTCCTCAGCAAAGCCCAGCTCTCCAGTAGCCTGCAGGAGGGGGTCATGCAGAAGTTTAACGGCCACGACGCCCTGCCCTTTAT
TCCAGCCGACAAGCTGAAAGATCTTACTTCCCGGGTGTTTAATGGAGAACCCGGCGCACACGATGCCAAACTGCGTTTTGAGTCCCAGGA
AATGAAAGGGATTGGGACACCCCCTAACACTACCCCTATCAAAAATGGCTCTCCAGAAATTAAGCTGAAAATCACCAAAACATACATGAA
TGGGAAGCCTCTCTTTGAATCTTCCATTTGTGGTGACAGTGCTGCTGATGTGTCTCAGTCAGAAGAAAATGGACAAAAACCAGAAAACAA
GGCGAGAAGGAACAGGAAGAGGAGCATAAAATATGACTCCTTGCTGGAGCAGGGCCTTGTCGAAGCAGCTCTTGTGTCTAAGATCTCAAG
TCCTTCAGATAAAAAGATTCCAGCTAAGAAAGAGTCTTGTCCAAACACTGGAAGAGACAAAGACCACCTGTTGAAATACAACGTTGGTGA
TTTGGTGTGGTCCAAAGTGTCGGGTTACCCTTGGTGGCCTTGCATGGTTTCTGCAGATCCACTCCTTCACAGCTATACCAAACTTAAAGG
TCAGAAAAAGAGTGCACGCCAGTATCACGTACAGTTCTTTGGTGACGCCCCAGAAAGAGCTTGGATATTTGAGAAGAGCCTCGTAGCTTT
TGAAGGAGAAGGACAGTTTGAAAAATTATGCCAGGAAAGTGCCAAGCAGGCACCCACGAAAGCTGAGAAAATTAAGCTATTGAAACCAAT
TTCAGGGAAATTGAGGGCCCAGTGGGAAATGGGCATTGTTCAAGCAGAAGAAGCTGCAAGCATGTCAGTGGAGGAGCGGAAAGCCAAGTT
CACCTTTCTCTATGTGGGGGACCAGCTTCATCTCAACCCTCAAGTAGCCAAGGAGGCTGGCATTGCTGCAGAGTCTTTGGGAGAAATGGC
AGAATCCTCAGGAGTCAGTGAAGAAGCTGCTGAAAACCCCAAGTCTGTGAGAGAAGAGTGCATTCCCATGAAGAGAAGGCGGAGGGCCAA
ACTGTGTAGCTCTGCAGAGACCCTGGAGAGTCACCCCGACATAGGGAAGAGTACTCCTCAAAAGACGGCAGAGGCTGACCCCAGAAGAGG
AGTAGGGTCTCCTCCTGGGAGGAAGAAGACCACAGTCTCCATGCCACGAAGCAGGAAGGGAGATGCAGCATCCCAGTTTTTGGTCTTCTG
TCAAAAACACAGGGATGAGGTGGTAGCTGAGCACCCAGATGCTTCAGGTGAGGAGATTGAAGAGCTGCTCAGGTCACAGTGGAGTCTGCT
GAGTGAGAAGCAGAGAGCACGCTACAACACCAAGTTTGCCCTGGTGGCCCCTGTCCAGGCTGAAGAAGACTCTGGTAATGTAAATGGGAA
AAAAAGAAACCACACAAAGAGGATACAGGACCCTACAGAAGATGCTGAAGCTGAGGACACACCCAGGAAAAGACTCAGGACGGACAAGCA
CAGTCTTCGGAAGAGAGACACAATCACTGACAAAACGGCCAGAACAAGCTCTTACAAGGCCATGGAGGCAGCCTCCTCGCTCAAGAGCCA
GGCAGCAACGAAAAATCTGTCTGATGCATGTAAACCACTGAAGAAGCGAAATCGGGCTTCCACGGCAGCATCTTCAGCTCTTGGGTTTAG
CAAAAGTTCATCTCCTTCTGCATCCTTAACTGAGAATGAGGTCTCGGACAGCCCGGGAGACGAGCCCTCGGAGTCCCCATACGAAAGTGC
AGACGAAACACAAACTGAAGTATCTGTCTCATCCAAAAAGTCTGAGCGAGGAGTGACTGCCAAAAAGGAGTATGTGTGCCAGCTGTGTGA
GAAGCCGGGCAGCCTCCTGCTCTGTGAAGGACCCTGCTGCGGAGCTTTCCACCTCGCCTGCCTTGGGCTTTCCCGGAGGCCAGAAGGGAG
GTTCACCTGCAGCGAGTGTGCCTCAGGGATTCACTCATGTTTCGTGTGTAAAGAGAGCAAGACAGATGTTAAGCGCTGTGTGGTAACTCA
GTGTGGAAAATTTTACCATGAGGCTTGTGTGAAAAAATACCCTCTGACTGTATTTGAGAGCCGAGGTTTCCGCTGCCCCCTCCACAGCTG
TGTGAGCTGCCATGCTTCCAACCCTTCAAACCCAAGGCCGTCAAAAGGTAAAATGATGCGGTGTGTCCGCTGCCCCGTTGCCTATCACAG
CGGGGATGCTTGTCTGGCAGCAGGATGCTCAGTGATCGCCTCCAACAGCATCATCTGCACTGCCCACTTCACTGCTCGGAAGGGGAAGCG
ACACCACGCCCACGTCAACGTGAGCTGGTGCTTCGTGTGCTCCAAAGGGGGGAGCCTTCTGTGCTGTGAGTCCTGCCCAGCGGCCTTCCA
CCCTGACTGCCTGAACATCGAGATGCCTGACGGCAGCTGGTTCTGCAATGACTGCAGGGCTGGGAAGAAGCTGCACTTCCAGGATATCAT
TTGGGTGAAACTTGGGAACTACAGATGGTGGCCGGCAGAAGTTTGCCATCCCAAAAATGTTCCCCCAAATATTCAGAAAATGAAGCACGA
GATTGGAGAATTCCCTGTGTTTTTCTTTGGGTCTAAAGATTATTACTGGACGCATCAGGCGCGAGTGTTCCCGTACATGGAGGGGGACCG
GGGCAGCCGCTACCAGGGGGTCAGAGGGATCGGAAGAGTCTTCAAAAACGGTCAAAAGGCTGAGTTTCAAATTCTGGATAATGTAGACTC
AACGGGAGAGTTGATAGTGAGATTACCCAAAGAAATAACAATTTCAGGCAGTTTCCAGGGCTTCCACCATCAGAAAATCAAGATATCGGA
GAACCGGATATCCCAGCAGTATCTGGCTACCCTTGAAAACAGGAAGCTGAAGAGGGAACTACCCTTTTCATTCCGATCAATTAATACGAG
AGAAAACCTGTATCTGGTGACAGAAACTCTGGAGACGGTAAAGGAGGAAACCCTGAAAAGCGACCGGCAATATAAATTTTGGAGCCAGAT
CTCTCAGGGCCATCTCAGCTATAAACACAAGGGCCAAAGGGAAGTGACCATCCCCCCAAATCGGGTCCTGAGCTATCGAGTAAAGCAGCT
TGTCTTCCCCAACAAGGAGACGATGAATATTCATTTCAGGGGCAAAACAAAATCCTTTCCAGAAGAGAAGGATGGTGCTTCATCCTGTTT
AGGAAAGTCTTTGGGTTCGGAGGATTCCAGAAACATGAAGGAGAAGTTGGAGGACATGGAGAGTGTCCTCAAGGACCTGACAGAGGAGAA
GAGAAAAGATGTGCTAAACTCCCTCGCTAAGTGCCTCGGCAAGGAGGATATTCGGCAGGATCTAGAGCAAAGAGTATCTGAGGTCCTGAT
TTCCGGGGAGCTACACATGGAGGACCCAGACAAGCCTCTCCTAAGCAGCCTTTTTAATGCTGCTGGGGTCTTGGTAGAAGCGCGTGCAAA
AGCCATTCTGGACTTCCTGGATGCCCTGCTAGAGCTGTCTGAAGAGCAGCAGTTTGTGGCTGAGGCCCTGGAGAAGGGGACCCTTCCTCT
GTTGAAGGACCAGGTGAAATCTGTCATGGAGCAGAACTGGGATGAGCTGGCCAGCAGTCCTCCTGACATGGACTATGACCCTGAGGCACG
AATTCTCTGTGCGCTGTATGTTGTTGTCTCTATCCTGCTGGAGCTGGCTGAGGGGCCTACCTCTGTCTCTTCCTAACTACAAAAGCCCTT
TCTCCCCACAAGCCTCTGGGTTTTCCCTTTACCAGTCTGTCCTCACTGCCATCGCCACTACCATCCTGTCACCAGTGGGACCTCTTTAAA
ACAAGCAGCCAACCATTCTTTGATGTATCCCATTCGCTCCATGTTAACATCCAAAACCAGCCTGGATTTCATACATGGACTTCTGATTAA

>99189_99189_11_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000382891_GSDMB_chr17_38068750_ENST00000418519_length(amino acids)=1301AA_BP=963
MGWMEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEGVMQKFNGHDALPFIPADKLKDLTSRVF
NGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNGSPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDS
LLEQGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFF
GDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNP
QVAKEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGKSTPQKTAEADPRRGVGSPPGRKKTTVS
MPRSRKGDAASQFLVFCQKHRDEVVAEHPDASGEEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTE
DAEAEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKRNRASTAASSALGFSKSSSPSASLTENE
VSDSPGDEPSESPYESADETQTEVSVSSKKSERGVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSC
FVCKESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKGKMMRCVRCPVAYHSGDACLAAGCSVIA
SNSIICTAHFTARKGKRHHAHVNVSWCFVCSKGGSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAE
VCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKNGQKAEFQILDNVDSTGELIVRLPKEIT
ISGSFQGFHHQKIKISENRISQQYLATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWSQISQGHLSYKHKGQR
EVTIPPNRVLSYRVKQLVFPNKETMNIHFRGKTKSFPEEKDGASSCLGKSLGSEDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLG
KEDIRQDLEQRVSEVLISGELHMEDPDKPLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQNW

--------------------------------------------------------------
>99189_99189_12_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000382891_GSDMB_chr17_38068750_ENST00000520542_length(transcript)=4224nt_BP=3020nt
TGGTCTTGAACTCCTGACCTTGTGATCCGCTCGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGTGCCTGTCCTAGAA
CCACTGGTAACTCTTAACTGTGTTCTAAGAACGGAAGCATCTGGGCTGGATGGAATTTAGCATCAAGCAGAGTCCCCTTTCTGTTCAGAG
TGTTGTAAAGTGCATAAAGATGAAGCAGGCACCAGAAATCCTCGGCAGTGCCAACGGGAAGACTCCGAGCTGCGAGGTGAACCGCGAGTG
TTCTGTGTTCCTCAGCAAAGCCCAGCTCTCCAGTAGCCTGCAGGAGGGGGTCATGCAGAAGTTTAACGGCCACGACGCCCTGCCCTTTAT
TCCAGCCGACAAGCTGAAAGATCTTACTTCCCGGGTGTTTAATGGAGAACCCGGCGCACACGATGCCAAACTGCGTTTTGAGTCCCAGGA
AATGAAAGGGATTGGGACACCCCCTAACACTACCCCTATCAAAAATGGCTCTCCAGAAATTAAGCTGAAAATCACCAAAACATACATGAA
TGGGAAGCCTCTCTTTGAATCTTCCATTTGTGGTGACAGTGCTGCTGATGTGTCTCAGTCAGAAGAAAATGGACAAAAACCAGAAAACAA
GGCGAGAAGGAACAGGAAGAGGAGCATAAAATATGACTCCTTGCTGGAGCAGGGCCTTGTCGAAGCAGCTCTTGTGTCTAAGATCTCAAG
TCCTTCAGATAAAAAGATTCCAGCTAAGAAAGAGTCTTGTCCAAACACTGGAAGAGACAAAGACCACCTGTTGAAATACAACGTTGGTGA
TTTGGTGTGGTCCAAAGTGTCGGGTTACCCTTGGTGGCCTTGCATGGTTTCTGCAGATCCACTCCTTCACAGCTATACCAAACTTAAAGG
TCAGAAAAAGAGTGCACGCCAGTATCACGTACAGTTCTTTGGTGACGCCCCAGAAAGAGCTTGGATATTTGAGAAGAGCCTCGTAGCTTT
TGAAGGAGAAGGACAGTTTGAAAAATTATGCCAGGAAAGTGCCAAGCAGGCACCCACGAAAGCTGAGAAAATTAAGCTATTGAAACCAAT
TTCAGGGAAATTGAGGGCCCAGTGGGAAATGGGCATTGTTCAAGCAGAAGAAGCTGCAAGCATGTCAGTGGAGGAGCGGAAAGCCAAGTT
CACCTTTCTCTATGTGGGGGACCAGCTTCATCTCAACCCTCAAGTAGCCAAGGAGGCTGGCATTGCTGCAGAGTCTTTGGGAGAAATGGC
AGAATCCTCAGGAGTCAGTGAAGAAGCTGCTGAAAACCCCAAGTCTGTGAGAGAAGAGTGCATTCCCATGAAGAGAAGGCGGAGGGCCAA
ACTGTGTAGCTCTGCAGAGACCCTGGAGAGTCACCCCGACATAGGGAAGAGTACTCCTCAAAAGACGGCAGAGGCTGACCCCAGAAGAGG
AGTAGGGTCTCCTCCTGGGAGGAAGAAGACCACAGTCTCCATGCCACGAAGCAGGAAGGGAGATGCAGCATCCCAGTTTTTGGTCTTCTG
TCAAAAACACAGGGATGAGGTGGTAGCTGAGCACCCAGATGCTTCAGGTGAGGAGATTGAAGAGCTGCTCAGGTCACAGTGGAGTCTGCT
GAGTGAGAAGCAGAGAGCACGCTACAACACCAAGTTTGCCCTGGTGGCCCCTGTCCAGGCTGAAGAAGACTCTGGTAATGTAAATGGGAA
AAAAAGAAACCACACAAAGAGGATACAGGACCCTACAGAAGATGCTGAAGCTGAGGACACACCCAGGAAAAGACTCAGGACGGACAAGCA
CAGTCTTCGGAAGAGAGACACAATCACTGACAAAACGGCCAGAACAAGCTCTTACAAGGCCATGGAGGCAGCCTCCTCGCTCAAGAGCCA
GGCAGCAACGAAAAATCTGTCTGATGCATGTAAACCACTGAAGAAGCGAAATCGGGCTTCCACGGCAGCATCTTCAGCTCTTGGGTTTAG
CAAAAGTTCATCTCCTTCTGCATCCTTAACTGAGAATGAGGTCTCGGACAGCCCGGGAGACGAGCCCTCGGAGTCCCCATACGAAAGTGC
AGACGAAACACAAACTGAAGTATCTGTCTCATCCAAAAAGTCTGAGCGAGGAGTGACTGCCAAAAAGGAGTATGTGTGCCAGCTGTGTGA
GAAGCCGGGCAGCCTCCTGCTCTGTGAAGGACCCTGCTGCGGAGCTTTCCACCTCGCCTGCCTTGGGCTTTCCCGGAGGCCAGAAGGGAG
GTTCACCTGCAGCGAGTGTGCCTCAGGGATTCACTCATGTTTCGTGTGTAAAGAGAGCAAGACAGATGTTAAGCGCTGTGTGGTAACTCA
GTGTGGAAAATTTTACCATGAGGCTTGTGTGAAAAAATACCCTCTGACTGTATTTGAGAGCCGAGGTTTCCGCTGCCCCCTCCACAGCTG
TGTGAGCTGCCATGCTTCCAACCCTTCAAACCCAAGGCCGTCAAAAGGTAAAATGATGCGGTGTGTCCGCTGCCCCGTTGCCTATCACAG
CGGGGATGCTTGTCTGGCAGCAGGATGCTCAGTGATCGCCTCCAACAGCATCATCTGCACTGCCCACTTCACTGCTCGGAAGGGGAAGCG
ACACCACGCCCACGTCAACGTGAGCTGGTGCTTCGTGTGCTCCAAAGGGGGGAGCCTTCTGTGCTGTGAGTCCTGCCCAGCGGCCTTCCA
CCCTGACTGCCTGAACATCGAGATGCCTGACGGCAGCTGGTTCTGCAATGACTGCAGGGCTGGGAAGAAGCTGCACTTCCAGGATATCAT
TTGGGTGAAACTTGGGAACTACAGATGGTGGCCGGCAGAAGTTTGCCATCCCAAAAATGTTCCCCCAAATATTCAGAAAATGAAGCACGA
GATTGGAGAATTCCCTGTGTTTTTCTTTGGGTCTAAAGATTATTACTGGACGCATCAGGCGCGAGTGTTCCCGTACATGGAGGGGGACCG
GGGCAGCCGCTACCAGGGGGTCAGAGGGATCGGAAGAGTCTTCAAAAACGGTCAAAAGGCTGAGTTTCAAATTCTGGATAATGTAGACTC
AACGGGAGAGTTGATAGTGAGATTACCCAAAGAAATAACAATTTCAGGCAGTTTCCAGGGCTTCCACCATCAGAAAATCAAGATATCGGA
GAACCGGATATCCCAGCAGTATCTGGCTACCCTTGAAAACAGGAAGCTGAAGAGGGAACTACCCTTTTCATTCCGATCAATTAATACGAG
AGAAAACCTGTATCTGGTGACAGAAACTCTGGAGACGGTAAAGGAGGAAACCCTGAAAAGCGACCGGCAATATAAATTTTGGAGCCAGAT
CTCTCAGGGCCATCTCAGCTATAAACACAAGGGCCAAAGGGAAGTGACCATCCCCCCAAATCGGGTCCTGAGCTATCGAGTAAAGCAGCT
TGTCTTCCCCAACAAGGAGACGATGAATATTCATTTCAGGGGCAAAACAAAATCCTTTCCAGAAGGAAAGTCTTTGGGTTCGGAGGATTC
CAGAAACATGAAGGAGAAGTTGGAGGACATGGAGAGTGTCCTCAAGGACCTGACAGAGGAGAAGAGAAAAGATGTGCTAAACTCCCTCGC
TAAGTGCCTCGGCAAGGAGGATATTCGGCAGGATCTAGAGCAAAGAGTATCTGAGGTCCTGATTTCCGGGGAGCTACACATGGAGGACCC
AGACAAGCCTCTCCTAAGCAGCCTTTTTAATGCTGCTGGGGTCTTGGTAGAAGCGCGTGCAAAAGCCATTCTGGACTTCCTGGATGCCCT
GCTAGAGCTGTCTGAAGAGCAGCAGTTTGTGGCTGAGGCCCTGGAGAAGGGGACCCTTCCTCTGTTGAAGGACCAGGTGAAATCTGTCAT
GGAGCAGAACTGGGATGAGCTGGCCAGCAGTCCTCCTGACATGGACTATGACCCTGAGGCACGAATTCTCTGTGCGCTGTATGTTGTTGT
CTCTATCCTGCTGGAGCTGGCTGAGGGGCCTACCTCTGTCTCTTCCTAACTACAAAAGCCCTTTCTCCCCACAAGCCTCTGGGTTTTCCC
TTTACCAGTCTGTCCTCACTGCCATCGCCACTACCATCCTGTCACCAGTGGGACCTCTTTAAAACAAGCAGCCAACCATTCTTTGATGTA

>99189_99189_12_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000382891_GSDMB_chr17_38068750_ENST00000520542_length(amino acids)=1292AA_BP=963
MGWMEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEGVMQKFNGHDALPFIPADKLKDLTSRVF
NGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNGSPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDS
LLEQGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFF
GDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNP
QVAKEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGKSTPQKTAEADPRRGVGSPPGRKKTTVS
MPRSRKGDAASQFLVFCQKHRDEVVAEHPDASGEEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTE
DAEAEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKRNRASTAASSALGFSKSSSPSASLTENE
VSDSPGDEPSESPYESADETQTEVSVSSKKSERGVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSC
FVCKESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKGKMMRCVRCPVAYHSGDACLAAGCSVIA
SNSIICTAHFTARKGKRHHAHVNVSWCFVCSKGGSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAE
VCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKNGQKAEFQILDNVDSTGELIVRLPKEIT
ISGSFQGFHHQKIKISENRISQQYLATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWSQISQGHLSYKHKGQR
EVTIPPNRVLSYRVKQLVFPNKETMNIHFRGKTKSFPEGKSLGSEDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLE
QRVSEVLISGELHMEDPDKPLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQNWDELASSPPD

--------------------------------------------------------------
>99189_99189_13_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000382892_GSDMB_chr17_38068750_ENST00000309481_length(transcript)=4389nt_BP=3195nt
TGGTCTTGAACTCCTGACCTTGTGATCCGCTCGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGTGCCTGTCCTAGAA
CCACTGGTAACTCTTAACTGCTGTCTGCTTTTCTGTGGAGACTGCGGGTTGCAGACACCAGCAGCCCCCTATTGCTGCACGTCAGGTGTC
CTCCACCTCAGTACTGTGGACATCTCGGGCCGCATAGCCCTGTTGCGCGGGCATCCTGTGCGTTGCAGGAGATGCAGCAGCATCCATGAC
CGCAACCCATCAGAGTGTTCTAAGAACGGAAGCATCTGGGCTGGATGGAATTTAGCATCAAGCAGAGTCCCCTTTCTGTTCAGAGTGTTG
TAAAGTGCATAAAGATGAAGCAGGCACCAGAAATCCTCGGCAGTGCCAACGGGAAGACTCCGAGCTGCGAGGTGAACCGCGAGTGTTCTG
TGTTCCTCAGCAAAGCCCAGCTCTCCAGTAGCCTGCAGGAGGGGGTCATGCAGAAGTTTAACGGCCACGACGCCCTGCCCTTTATTCCAG
CCGACAAGCTGAAAGATCTTACTTCCCGGGTGTTTAATGGAGAACCCGGCGCACACGATGCCAAACTGCGTTTTGAGTCCCAGGAAATGA
AAGGGATTGGGACACCCCCTAACACTACCCCTATCAAAAATGGCTCTCCAGAAATTAAGCTGAAAATCACCAAAACATACATGAATGGGA
AGCCTCTCTTTGAATCTTCCATTTGTGGTGACAGTGCTGCTGATGTGTCTCAGTCAGAAGAAAATGGACAAAAACCAGAAAACAAGGCGA
GAAGGAACAGGAAGAGGAGCATAAAATATGACTCCTTGCTGGAGCAGGGCCTTGTCGAAGCAGCTCTTGTGTCTAAGATCTCAAGTCCTT
CAGATAAAAAGATTCCAGCTAAGAAAGAGTCTTGTCCAAACACTGGAAGAGACAAAGACCACCTGTTGAAATACAACGTTGGTGATTTGG
TGTGGTCCAAAGTGTCGGGTTACCCTTGGTGGCCTTGCATGGTTTCTGCAGATCCACTCCTTCACAGCTATACCAAACTTAAAGGTCAGA
AAAAGAGTGCACGCCAGTATCACGTACAGTTCTTTGGTGACGCCCCAGAAAGAGCTTGGATATTTGAGAAGAGCCTCGTAGCTTTTGAAG
GAGAAGGACAGTTTGAAAAATTATGCCAGGAAAGTGCCAAGCAGGCACCCACGAAAGCTGAGAAAATTAAGCTATTGAAACCAATTTCAG
GGAAATTGAGGGCCCAGTGGGAAATGGGCATTGTTCAAGCAGAAGAAGCTGCAAGCATGTCAGTGGAGGAGCGGAAAGCCAAGTTCACCT
TTCTCTATGTGGGGGACCAGCTTCATCTCAACCCTCAAGTAGCCAAGGAGGCTGGCATTGCTGCAGAGTCTTTGGGAGAAATGGCAGAAT
CCTCAGGAGTCAGTGAAGAAGCTGCTGAAAACCCCAAGTCTGTGAGAGAAGAGTGCATTCCCATGAAGAGAAGGCGGAGGGCCAAACTGT
GTAGCTCTGCAGAGACCCTGGAGAGTCACCCCGACATAGGGAAGAGTACTCCTCAAAAGACGGCAGAGGCTGACCCCAGAAGAGGAGTAG
GGTCTCCTCCTGGGAGGAAGAAGACCACAGTCTCCATGCCACGAAGCAGGAAGGGAGATGCAGCATCCCAGTTTTTGGTCTTCTGTCAAA
AACACAGGGATGAGGTGGTAGCTGAGCACCCAGATGCTTCAGGTGAGGAGATTGAAGAGCTGCTCAGGTCACAGTGGAGTCTGCTGAGTG
AGAAGCAGAGAGCACGCTACAACACCAAGTTTGCCCTGGTGGCCCCTGTCCAGGCTGAAGAAGACTCTGGTAATGTAAATGGGAAAAAAA
GAAACCACACAAAGAGGATACAGGACCCTACAGAAGATGCTGAAGCTGAGGACACACCCAGGAAAAGACTCAGGACGGACAAGCACAGTC
TTCGGAAGAGAGACACAATCACTGACAAAACGGCCAGAACAAGCTCTTACAAGGCCATGGAGGCAGCCTCCTCGCTCAAGAGCCAGGCAG
CAACGAAAAATCTGTCTGATGCATGTAAACCACTGAAGAAGCGAAATCGGGCTTCCACGGCAGCATCTTCAGCTCTTGGGTTTAGCAAAA
GTTCATCTCCTTCTGCATCCTTAACTGAGAATGAGGTCTCGGACAGCCCGGGAGACGAGCCCTCGGAGTCCCCATACGAAAGTGCAGACG
AAACACAAACTGAAGTATCTGTCTCATCCAAAAAGTCTGAGCGAGGAGTGACTGCCAAAAAGGAGTATGTGTGCCAGCTGTGTGAGAAGC
CGGGCAGCCTCCTGCTCTGTGAAGGACCCTGCTGCGGAGCTTTCCACCTCGCCTGCCTTGGGCTTTCCCGGAGGCCAGAAGGGAGGTTCA
CCTGCAGCGAGTGTGCCTCAGGGATTCACTCATGTTTCGTGTGTAAAGAGAGCAAGACAGATGTTAAGCGCTGTGTGGTAACTCAGTGTG
GAAAATTTTACCATGAGGCTTGTGTGAAAAAATACCCTCTGACTGTATTTGAGAGCCGAGGTTTCCGCTGCCCCCTCCACAGCTGTGTGA
GCTGCCATGCTTCCAACCCTTCAAACCCAAGGCCGTCAAAAGGTAAAATGATGCGGTGTGTCCGCTGCCCCGTTGCCTATCACAGCGGGG
ATGCTTGTCTGGCAGCAGGATGCTCAGTGATCGCCTCCAACAGCATCATCTGCACTGCCCACTTCACTGCTCGGAAGGGGAAGCGACACC
ACGCCCACGTCAACGTGAGCTGGTGCTTCGTGTGCTCCAAAGGGGGGAGCCTTCTGTGCTGTGAGTCCTGCCCAGCGGCCTTCCACCCTG
ACTGCCTGAACATCGAGATGCCTGACGGCAGCTGGTTCTGCAATGACTGCAGGGCTGGGAAGAAGCTGCACTTCCAGGATATCATTTGGG
TGAAACTTGGGAACTACAGATGGTGGCCGGCAGAAGTTTGCCATCCCAAAAATGTTCCCCCAAATATTCAGAAAATGAAGCACGAGATTG
GAGAATTCCCTGTGTTTTTCTTTGGGTCTAAAGATTATTACTGGACGCATCAGGCGCGAGTGTTCCCGTACATGGAGGGGGACCGGGGCA
GCCGCTACCAGGGGGTCAGAGGGATCGGAAGAGTCTTCAAAAACGGTCAAAAGGCTGAGTTTCAAATTCTGGATAATGTAGACTCAACGG
GAGAGTTGATAGTGAGATTACCCAAAGAAATAACAATTTCAGGCAGTTTCCAGGGCTTCCACCATCAGAAAATCAAGATATCGGAGAACC
GGATATCCCAGCAGTATCTGGCTACCCTTGAAAACAGGAAGCTGAAGAGGGAACTACCCTTTTCATTCCGATCAATTAATACGAGAGAAA
ACCTGTATCTGGTGACAGAAACTCTGGAGACGGTAAAGGAGGAAACCCTGAAAAGCGACCGGCAATATAAATTTTGGAGCCAGATCTCTC
AGGGCCATCTCAGCTATAAACACAAGGGCCAAAGGGAAGTGACCATCCCCCCAAATCGGGTCCTGAGCTATCGAGTAAAGCAGCTTGTCT
TCCCCAACAAGGAGACGATGAAGAAGGATGGTGCTTCATCCTGTTTAGGAAAGTCTTTGGGTTCGGAGGATTCCAGAAACATGAAGGAGA
AGTTGGAGGACATGGAGAGTGTCCTCAAGGACCTGACAGAGGAGAAGAGAAAAGATGTGCTAAACTCCCTCGCTAAGTGCCTCGGCAAGG
AGGATATTCGGCAGGATCTAGAGCAAAGAGTATCTGAGGTCCTGATTTCCGGGGAGCTACACATGGAGGACCCAGACAAGCCTCTCCTAA
GCAGCCTTTTTAATGCTGCTGGGGTCTTGGTAGAAGCGCGTGCAAAAGCCATTCTGGACTTCCTGGATGCCCTGCTAGAGCTGTCTGAAG
AGCAGCAGTTTGTGGCTGAGGCCCTGGAGAAGGGGACCCTTCCTCTGTTGAAGGACCAGGTGAAATCTGTCATGGAGCAGAACTGGGATG
AGCTGGCCAGCAGTCCTCCTGACATGGACTATGACCCTGAGGCACGAATTCTCTGTGCGCTGTATGTTGTTGTCTCTATCCTGCTGGAGC
TGGCTGAGGGGCCTACCTCTGTCTCTTCCTAACTACAAAAGCCCTTTCTCCCCACAAGCCTCTGGGTTTTCCCTTTACCAGTCTGTCCTC
ACTGCCATCGCCACTACCATCCTGTCACCAGTGGGACCTCTTTAAAACAAGCAGCCAACCATTCTTTGATGTATCCCATTCGCTCCATGT

>99189_99189_13_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000382892_GSDMB_chr17_38068750_ENST00000309481_length(amino acids)=1288AA_BP=963
MGWMEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEGVMQKFNGHDALPFIPADKLKDLTSRVF
NGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNGSPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDS
LLEQGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFF
GDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNP
QVAKEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGKSTPQKTAEADPRRGVGSPPGRKKTTVS
MPRSRKGDAASQFLVFCQKHRDEVVAEHPDASGEEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTE
DAEAEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKRNRASTAASSALGFSKSSSPSASLTENE
VSDSPGDEPSESPYESADETQTEVSVSSKKSERGVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSC
FVCKESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKGKMMRCVRCPVAYHSGDACLAAGCSVIA
SNSIICTAHFTARKGKRHHAHVNVSWCFVCSKGGSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAE
VCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKNGQKAEFQILDNVDSTGELIVRLPKEIT
ISGSFQGFHHQKIKISENRISQQYLATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWSQISQGHLSYKHKGQR
EVTIPPNRVLSYRVKQLVFPNKETMKKDGASSCLGKSLGSEDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVS
EVLISGELHMEDPDKPLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQNWDELASSPPDMDYD

--------------------------------------------------------------
>99189_99189_14_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000382892_GSDMB_chr17_38068750_ENST00000360317_length(transcript)=4428nt_BP=3195nt
TGGTCTTGAACTCCTGACCTTGTGATCCGCTCGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGTGCCTGTCCTAGAA
CCACTGGTAACTCTTAACTGCTGTCTGCTTTTCTGTGGAGACTGCGGGTTGCAGACACCAGCAGCCCCCTATTGCTGCACGTCAGGTGTC
CTCCACCTCAGTACTGTGGACATCTCGGGCCGCATAGCCCTGTTGCGCGGGCATCCTGTGCGTTGCAGGAGATGCAGCAGCATCCATGAC
CGCAACCCATCAGAGTGTTCTAAGAACGGAAGCATCTGGGCTGGATGGAATTTAGCATCAAGCAGAGTCCCCTTTCTGTTCAGAGTGTTG
TAAAGTGCATAAAGATGAAGCAGGCACCAGAAATCCTCGGCAGTGCCAACGGGAAGACTCCGAGCTGCGAGGTGAACCGCGAGTGTTCTG
TGTTCCTCAGCAAAGCCCAGCTCTCCAGTAGCCTGCAGGAGGGGGTCATGCAGAAGTTTAACGGCCACGACGCCCTGCCCTTTATTCCAG
CCGACAAGCTGAAAGATCTTACTTCCCGGGTGTTTAATGGAGAACCCGGCGCACACGATGCCAAACTGCGTTTTGAGTCCCAGGAAATGA
AAGGGATTGGGACACCCCCTAACACTACCCCTATCAAAAATGGCTCTCCAGAAATTAAGCTGAAAATCACCAAAACATACATGAATGGGA
AGCCTCTCTTTGAATCTTCCATTTGTGGTGACAGTGCTGCTGATGTGTCTCAGTCAGAAGAAAATGGACAAAAACCAGAAAACAAGGCGA
GAAGGAACAGGAAGAGGAGCATAAAATATGACTCCTTGCTGGAGCAGGGCCTTGTCGAAGCAGCTCTTGTGTCTAAGATCTCAAGTCCTT
CAGATAAAAAGATTCCAGCTAAGAAAGAGTCTTGTCCAAACACTGGAAGAGACAAAGACCACCTGTTGAAATACAACGTTGGTGATTTGG
TGTGGTCCAAAGTGTCGGGTTACCCTTGGTGGCCTTGCATGGTTTCTGCAGATCCACTCCTTCACAGCTATACCAAACTTAAAGGTCAGA
AAAAGAGTGCACGCCAGTATCACGTACAGTTCTTTGGTGACGCCCCAGAAAGAGCTTGGATATTTGAGAAGAGCCTCGTAGCTTTTGAAG
GAGAAGGACAGTTTGAAAAATTATGCCAGGAAAGTGCCAAGCAGGCACCCACGAAAGCTGAGAAAATTAAGCTATTGAAACCAATTTCAG
GGAAATTGAGGGCCCAGTGGGAAATGGGCATTGTTCAAGCAGAAGAAGCTGCAAGCATGTCAGTGGAGGAGCGGAAAGCCAAGTTCACCT
TTCTCTATGTGGGGGACCAGCTTCATCTCAACCCTCAAGTAGCCAAGGAGGCTGGCATTGCTGCAGAGTCTTTGGGAGAAATGGCAGAAT
CCTCAGGAGTCAGTGAAGAAGCTGCTGAAAACCCCAAGTCTGTGAGAGAAGAGTGCATTCCCATGAAGAGAAGGCGGAGGGCCAAACTGT
GTAGCTCTGCAGAGACCCTGGAGAGTCACCCCGACATAGGGAAGAGTACTCCTCAAAAGACGGCAGAGGCTGACCCCAGAAGAGGAGTAG
GGTCTCCTCCTGGGAGGAAGAAGACCACAGTCTCCATGCCACGAAGCAGGAAGGGAGATGCAGCATCCCAGTTTTTGGTCTTCTGTCAAA
AACACAGGGATGAGGTGGTAGCTGAGCACCCAGATGCTTCAGGTGAGGAGATTGAAGAGCTGCTCAGGTCACAGTGGAGTCTGCTGAGTG
AGAAGCAGAGAGCACGCTACAACACCAAGTTTGCCCTGGTGGCCCCTGTCCAGGCTGAAGAAGACTCTGGTAATGTAAATGGGAAAAAAA
GAAACCACACAAAGAGGATACAGGACCCTACAGAAGATGCTGAAGCTGAGGACACACCCAGGAAAAGACTCAGGACGGACAAGCACAGTC
TTCGGAAGAGAGACACAATCACTGACAAAACGGCCAGAACAAGCTCTTACAAGGCCATGGAGGCAGCCTCCTCGCTCAAGAGCCAGGCAG
CAACGAAAAATCTGTCTGATGCATGTAAACCACTGAAGAAGCGAAATCGGGCTTCCACGGCAGCATCTTCAGCTCTTGGGTTTAGCAAAA
GTTCATCTCCTTCTGCATCCTTAACTGAGAATGAGGTCTCGGACAGCCCGGGAGACGAGCCCTCGGAGTCCCCATACGAAAGTGCAGACG
AAACACAAACTGAAGTATCTGTCTCATCCAAAAAGTCTGAGCGAGGAGTGACTGCCAAAAAGGAGTATGTGTGCCAGCTGTGTGAGAAGC
CGGGCAGCCTCCTGCTCTGTGAAGGACCCTGCTGCGGAGCTTTCCACCTCGCCTGCCTTGGGCTTTCCCGGAGGCCAGAAGGGAGGTTCA
CCTGCAGCGAGTGTGCCTCAGGGATTCACTCATGTTTCGTGTGTAAAGAGAGCAAGACAGATGTTAAGCGCTGTGTGGTAACTCAGTGTG
GAAAATTTTACCATGAGGCTTGTGTGAAAAAATACCCTCTGACTGTATTTGAGAGCCGAGGTTTCCGCTGCCCCCTCCACAGCTGTGTGA
GCTGCCATGCTTCCAACCCTTCAAACCCAAGGCCGTCAAAAGGTAAAATGATGCGGTGTGTCCGCTGCCCCGTTGCCTATCACAGCGGGG
ATGCTTGTCTGGCAGCAGGATGCTCAGTGATCGCCTCCAACAGCATCATCTGCACTGCCCACTTCACTGCTCGGAAGGGGAAGCGACACC
ACGCCCACGTCAACGTGAGCTGGTGCTTCGTGTGCTCCAAAGGGGGGAGCCTTCTGTGCTGTGAGTCCTGCCCAGCGGCCTTCCACCCTG
ACTGCCTGAACATCGAGATGCCTGACGGCAGCTGGTTCTGCAATGACTGCAGGGCTGGGAAGAAGCTGCACTTCCAGGATATCATTTGGG
TGAAACTTGGGAACTACAGATGGTGGCCGGCAGAAGTTTGCCATCCCAAAAATGTTCCCCCAAATATTCAGAAAATGAAGCACGAGATTG
GAGAATTCCCTGTGTTTTTCTTTGGGTCTAAAGATTATTACTGGACGCATCAGGCGCGAGTGTTCCCGTACATGGAGGGGGACCGGGGCA
GCCGCTACCAGGGGGTCAGAGGGATCGGAAGAGTCTTCAAAAACGGTCAAAAGGCTGAGTTTCAAATTCTGGATAATGTAGACTCAACGG
GAGAGTTGATAGTGAGATTACCCAAAGAAATAACAATTTCAGGCAGTTTCCAGGGCTTCCACCATCAGAAAATCAAGATATCGGAGAACC
GGATATCCCAGCAGTATCTGGCTACCCTTGAAAACAGGAAGCTGAAGAGGGAACTACCCTTTTCATTCCGATCAATTAATACGAGAGAAA
ACCTGTATCTGGTGACAGAAACTCTGGAGACGGTAAAGGAGGAAACCCTGAAAAGCGACCGGCAATATAAATTTTGGAGCCAGATCTCTC
AGGGCCATCTCAGCTATAAACACAAGGGCCAAAGGGAAGTGACCATCCCCCCAAATCGGGTCCTGAGCTATCGAGTAAAGCAGCTTGTCT
TCCCCAACAAGGAGACGATGAATATTCATTTCAGGGGCAAAACAAAATCCTTTCCAGAAGAGAAGGATGGTGCTTCATCCTGTTTAGGAA
AGTCTTTGGGTTCGGAGGATTCCAGAAACATGAAGGAGAAGTTGGAGGACATGGAGAGTGTCCTCAAGGACCTGACAGAGGAGAAGAGAA
AAGATGTGCTAAACTCCCTCGCTAAGTGCCTCGGCAAGGAGGATATTCGGCAGGATCTAGAGCAAAGAGTATCTGAGGTCCTGATTTCCG
GGGAGCTACACATGGAGGACCCAGACAAGCCTCTCCTAAGCAGCCTTTTTAATGCTGCTGGGGTCTTGGTAGAAGCGCGTGCAAAAGCCA
TTCTGGACTTCCTGGATGCCCTGCTAGAGCTGTCTGAAGAGCAGCAGTTTGTGGCTGAGGCCCTGGAGAAGGGGACCCTTCCTCTGTTGA
AGGACCAGGTGAAATCTGTCATGGAGCAGAACTGGGATGAGCTGGCCAGCAGTCCTCCTGACATGGACTATGACCCTGAGGCACGAATTC
TCTGTGCGCTGTATGTTGTTGTCTCTATCCTGCTGGAGCTGGCTGAGGGGCCTACCTCTGTCTCTTCCTAACTACAAAAGCCCTTTCTCC
CCACAAGCCTCTGGGTTTTCCCTTTACCAGTCTGTCCTCACTGCCATCGCCACTACCATCCTGTCACCAGTGGGACCTCTTTAAAACAAG
CAGCCAACCATTCTTTGATGTATCCCATTCGCTCCATGTTAACATCCAAAACCAGCCTGGATTTCATACATGGACTTCTGATTAAAAGTG

>99189_99189_14_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000382892_GSDMB_chr17_38068750_ENST00000360317_length(amino acids)=1301AA_BP=963
MGWMEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEGVMQKFNGHDALPFIPADKLKDLTSRVF
NGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNGSPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDS
LLEQGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFF
GDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNP
QVAKEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGKSTPQKTAEADPRRGVGSPPGRKKTTVS
MPRSRKGDAASQFLVFCQKHRDEVVAEHPDASGEEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTE
DAEAEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKRNRASTAASSALGFSKSSSPSASLTENE
VSDSPGDEPSESPYESADETQTEVSVSSKKSERGVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSC
FVCKESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKGKMMRCVRCPVAYHSGDACLAAGCSVIA
SNSIICTAHFTARKGKRHHAHVNVSWCFVCSKGGSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAE
VCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKNGQKAEFQILDNVDSTGELIVRLPKEIT
ISGSFQGFHHQKIKISENRISQQYLATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWSQISQGHLSYKHKGQR
EVTIPPNRVLSYRVKQLVFPNKETMNIHFRGKTKSFPEEKDGASSCLGKSLGSEDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLG
KEDIRQDLEQRVSEVLISGELHMEDPDKPLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQNW

--------------------------------------------------------------
>99189_99189_15_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000382892_GSDMB_chr17_38068750_ENST00000394175_length(transcript)=4362nt_BP=3195nt
TGGTCTTGAACTCCTGACCTTGTGATCCGCTCGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGTGCCTGTCCTAGAA
CCACTGGTAACTCTTAACTGCTGTCTGCTTTTCTGTGGAGACTGCGGGTTGCAGACACCAGCAGCCCCCTATTGCTGCACGTCAGGTGTC
CTCCACCTCAGTACTGTGGACATCTCGGGCCGCATAGCCCTGTTGCGCGGGCATCCTGTGCGTTGCAGGAGATGCAGCAGCATCCATGAC
CGCAACCCATCAGAGTGTTCTAAGAACGGAAGCATCTGGGCTGGATGGAATTTAGCATCAAGCAGAGTCCCCTTTCTGTTCAGAGTGTTG
TAAAGTGCATAAAGATGAAGCAGGCACCAGAAATCCTCGGCAGTGCCAACGGGAAGACTCCGAGCTGCGAGGTGAACCGCGAGTGTTCTG
TGTTCCTCAGCAAAGCCCAGCTCTCCAGTAGCCTGCAGGAGGGGGTCATGCAGAAGTTTAACGGCCACGACGCCCTGCCCTTTATTCCAG
CCGACAAGCTGAAAGATCTTACTTCCCGGGTGTTTAATGGAGAACCCGGCGCACACGATGCCAAACTGCGTTTTGAGTCCCAGGAAATGA
AAGGGATTGGGACACCCCCTAACACTACCCCTATCAAAAATGGCTCTCCAGAAATTAAGCTGAAAATCACCAAAACATACATGAATGGGA
AGCCTCTCTTTGAATCTTCCATTTGTGGTGACAGTGCTGCTGATGTGTCTCAGTCAGAAGAAAATGGACAAAAACCAGAAAACAAGGCGA
GAAGGAACAGGAAGAGGAGCATAAAATATGACTCCTTGCTGGAGCAGGGCCTTGTCGAAGCAGCTCTTGTGTCTAAGATCTCAAGTCCTT
CAGATAAAAAGATTCCAGCTAAGAAAGAGTCTTGTCCAAACACTGGAAGAGACAAAGACCACCTGTTGAAATACAACGTTGGTGATTTGG
TGTGGTCCAAAGTGTCGGGTTACCCTTGGTGGCCTTGCATGGTTTCTGCAGATCCACTCCTTCACAGCTATACCAAACTTAAAGGTCAGA
AAAAGAGTGCACGCCAGTATCACGTACAGTTCTTTGGTGACGCCCCAGAAAGAGCTTGGATATTTGAGAAGAGCCTCGTAGCTTTTGAAG
GAGAAGGACAGTTTGAAAAATTATGCCAGGAAAGTGCCAAGCAGGCACCCACGAAAGCTGAGAAAATTAAGCTATTGAAACCAATTTCAG
GGAAATTGAGGGCCCAGTGGGAAATGGGCATTGTTCAAGCAGAAGAAGCTGCAAGCATGTCAGTGGAGGAGCGGAAAGCCAAGTTCACCT
TTCTCTATGTGGGGGACCAGCTTCATCTCAACCCTCAAGTAGCCAAGGAGGCTGGCATTGCTGCAGAGTCTTTGGGAGAAATGGCAGAAT
CCTCAGGAGTCAGTGAAGAAGCTGCTGAAAACCCCAAGTCTGTGAGAGAAGAGTGCATTCCCATGAAGAGAAGGCGGAGGGCCAAACTGT
GTAGCTCTGCAGAGACCCTGGAGAGTCACCCCGACATAGGGAAGAGTACTCCTCAAAAGACGGCAGAGGCTGACCCCAGAAGAGGAGTAG
GGTCTCCTCCTGGGAGGAAGAAGACCACAGTCTCCATGCCACGAAGCAGGAAGGGAGATGCAGCATCCCAGTTTTTGGTCTTCTGTCAAA
AACACAGGGATGAGGTGGTAGCTGAGCACCCAGATGCTTCAGGTGAGGAGATTGAAGAGCTGCTCAGGTCACAGTGGAGTCTGCTGAGTG
AGAAGCAGAGAGCACGCTACAACACCAAGTTTGCCCTGGTGGCCCCTGTCCAGGCTGAAGAAGACTCTGGTAATGTAAATGGGAAAAAAA
GAAACCACACAAAGAGGATACAGGACCCTACAGAAGATGCTGAAGCTGAGGACACACCCAGGAAAAGACTCAGGACGGACAAGCACAGTC
TTCGGAAGAGAGACACAATCACTGACAAAACGGCCAGAACAAGCTCTTACAAGGCCATGGAGGCAGCCTCCTCGCTCAAGAGCCAGGCAG
CAACGAAAAATCTGTCTGATGCATGTAAACCACTGAAGAAGCGAAATCGGGCTTCCACGGCAGCATCTTCAGCTCTTGGGTTTAGCAAAA
GTTCATCTCCTTCTGCATCCTTAACTGAGAATGAGGTCTCGGACAGCCCGGGAGACGAGCCCTCGGAGTCCCCATACGAAAGTGCAGACG
AAACACAAACTGAAGTATCTGTCTCATCCAAAAAGTCTGAGCGAGGAGTGACTGCCAAAAAGGAGTATGTGTGCCAGCTGTGTGAGAAGC
CGGGCAGCCTCCTGCTCTGTGAAGGACCCTGCTGCGGAGCTTTCCACCTCGCCTGCCTTGGGCTTTCCCGGAGGCCAGAAGGGAGGTTCA
CCTGCAGCGAGTGTGCCTCAGGGATTCACTCATGTTTCGTGTGTAAAGAGAGCAAGACAGATGTTAAGCGCTGTGTGGTAACTCAGTGTG
GAAAATTTTACCATGAGGCTTGTGTGAAAAAATACCCTCTGACTGTATTTGAGAGCCGAGGTTTCCGCTGCCCCCTCCACAGCTGTGTGA
GCTGCCATGCTTCCAACCCTTCAAACCCAAGGCCGTCAAAAGGTAAAATGATGCGGTGTGTCCGCTGCCCCGTTGCCTATCACAGCGGGG
ATGCTTGTCTGGCAGCAGGATGCTCAGTGATCGCCTCCAACAGCATCATCTGCACTGCCCACTTCACTGCTCGGAAGGGGAAGCGACACC
ACGCCCACGTCAACGTGAGCTGGTGCTTCGTGTGCTCCAAAGGGGGGAGCCTTCTGTGCTGTGAGTCCTGCCCAGCGGCCTTCCACCCTG
ACTGCCTGAACATCGAGATGCCTGACGGCAGCTGGTTCTGCAATGACTGCAGGGCTGGGAAGAAGCTGCACTTCCAGGATATCATTTGGG
TGAAACTTGGGAACTACAGATGGTGGCCGGCAGAAGTTTGCCATCCCAAAAATGTTCCCCCAAATATTCAGAAAATGAAGCACGAGATTG
GAGAATTCCCTGTGTTTTTCTTTGGGTCTAAAGATTATTACTGGACGCATCAGGCGCGAGTGTTCCCGTACATGGAGGGGGACCGGGGCA
GCCGCTACCAGGGGGTCAGAGGGATCGGAAGAGTCTTCAAAAACGGTCAAAAGGCTGAGTTTCAAATTCTGGATAATGTAGACTCAACGG
GAGAGTTGATAGTGAGATTACCCAAAGAAATAACAATTTCAGGCAGTTTCCAGGGCTTCCACCATCAGAAAATCAAGATATCGGAGAACC
GGATATCCCAGCAGTATCTGGCTACCCTTGAAAACAGGAAGCTGAAGAGGGAACTACCCTTTTCATTCCGATCAATTAATACGAGAGAAA
ACCTGTATCTGGTGACAGAAACTCTGGAGACGGTAAAGGAGGAAACCCTGAAAAGCGACCGGCAATATAAATTTTGGAGCCAGATCTCTC
AGGGCCATCTCAGCTATAAACACAAGGGCCAAAGGGAAGTGACCATCCCCCCAAATCGGGTCCTGAGCTATCGAGTAAAGCAGCTTGTCT
TCCCCAACAAGGAGACGATGAGAAAGTCTTTGGGTTCGGAGGATTCCAGAAACATGAAGGAGAAGTTGGAGGACATGGAGAGTGTCCTCA
AGGACCTGACAGAGGAGAAGAGAAAAGATGTGCTAAACTCCCTCGCTAAGTGCCTCGGCAAGGAGGATATTCGGCAGGATCTAGAGCAAA
GAGTATCTGAGGTCCTGATTTCCGGGGAGCTACACATGGAGGACCCAGACAAGCCTCTCCTAAGCAGCCTTTTTAATGCTGCTGGGGTCT
TGGTAGAAGCGCGTGCAAAAGCCATTCTGGACTTCCTGGATGCCCTGCTAGAGCTGTCTGAAGAGCAGCAGTTTGTGGCTGAGGCCCTGG
AGAAGGGGACCCTTCCTCTGTTGAAGGACCAGGTGAAATCTGTCATGGAGCAGAACTGGGATGAGCTGGCCAGCAGTCCTCCTGACATGG
ACTATGACCCTGAGGCACGAATTCTCTGTGCGCTGTATGTTGTTGTCTCTATCCTGCTGGAGCTGGCTGAGGGGCCTACCTCTGTCTCTT
CCTAACTACAAAAGCCCTTTCTCCCCACAAGCCTCTGGGTTTTCCCTTTACCAGTCTGTCCTCACTGCCATCGCCACTACCATCCTGTCA
CCAGTGGGACCTCTTTAAAACAAGCAGCCAACCATTCTTTGATGTATCCCATTCGCTCCATGTTAACATCCAAAACCAGCCTGGATTTCA

>99189_99189_15_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000382892_GSDMB_chr17_38068750_ENST00000394175_length(amino acids)=1279AA_BP=963
MGWMEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEGVMQKFNGHDALPFIPADKLKDLTSRVF
NGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNGSPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDS
LLEQGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFF
GDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNP
QVAKEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGKSTPQKTAEADPRRGVGSPPGRKKTTVS
MPRSRKGDAASQFLVFCQKHRDEVVAEHPDASGEEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTE
DAEAEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKRNRASTAASSALGFSKSSSPSASLTENE
VSDSPGDEPSESPYESADETQTEVSVSSKKSERGVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSC
FVCKESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKGKMMRCVRCPVAYHSGDACLAAGCSVIA
SNSIICTAHFTARKGKRHHAHVNVSWCFVCSKGGSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAE
VCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKNGQKAEFQILDNVDSTGELIVRLPKEIT
ISGSFQGFHHQKIKISENRISQQYLATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWSQISQGHLSYKHKGQR
EVTIPPNRVLSYRVKQLVFPNKETMRKSLGSEDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELH
MEDPDKPLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQNWDELASSPPDMDYDPEARILCAL

--------------------------------------------------------------
>99189_99189_16_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000382892_GSDMB_chr17_38068750_ENST00000394179_length(transcript)=4411nt_BP=3195nt
TGGTCTTGAACTCCTGACCTTGTGATCCGCTCGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGTGCCTGTCCTAGAA
CCACTGGTAACTCTTAACTGCTGTCTGCTTTTCTGTGGAGACTGCGGGTTGCAGACACCAGCAGCCCCCTATTGCTGCACGTCAGGTGTC
CTCCACCTCAGTACTGTGGACATCTCGGGCCGCATAGCCCTGTTGCGCGGGCATCCTGTGCGTTGCAGGAGATGCAGCAGCATCCATGAC
CGCAACCCATCAGAGTGTTCTAAGAACGGAAGCATCTGGGCTGGATGGAATTTAGCATCAAGCAGAGTCCCCTTTCTGTTCAGAGTGTTG
TAAAGTGCATAAAGATGAAGCAGGCACCAGAAATCCTCGGCAGTGCCAACGGGAAGACTCCGAGCTGCGAGGTGAACCGCGAGTGTTCTG
TGTTCCTCAGCAAAGCCCAGCTCTCCAGTAGCCTGCAGGAGGGGGTCATGCAGAAGTTTAACGGCCACGACGCCCTGCCCTTTATTCCAG
CCGACAAGCTGAAAGATCTTACTTCCCGGGTGTTTAATGGAGAACCCGGCGCACACGATGCCAAACTGCGTTTTGAGTCCCAGGAAATGA
AAGGGATTGGGACACCCCCTAACACTACCCCTATCAAAAATGGCTCTCCAGAAATTAAGCTGAAAATCACCAAAACATACATGAATGGGA
AGCCTCTCTTTGAATCTTCCATTTGTGGTGACAGTGCTGCTGATGTGTCTCAGTCAGAAGAAAATGGACAAAAACCAGAAAACAAGGCGA
GAAGGAACAGGAAGAGGAGCATAAAATATGACTCCTTGCTGGAGCAGGGCCTTGTCGAAGCAGCTCTTGTGTCTAAGATCTCAAGTCCTT
CAGATAAAAAGATTCCAGCTAAGAAAGAGTCTTGTCCAAACACTGGAAGAGACAAAGACCACCTGTTGAAATACAACGTTGGTGATTTGG
TGTGGTCCAAAGTGTCGGGTTACCCTTGGTGGCCTTGCATGGTTTCTGCAGATCCACTCCTTCACAGCTATACCAAACTTAAAGGTCAGA
AAAAGAGTGCACGCCAGTATCACGTACAGTTCTTTGGTGACGCCCCAGAAAGAGCTTGGATATTTGAGAAGAGCCTCGTAGCTTTTGAAG
GAGAAGGACAGTTTGAAAAATTATGCCAGGAAAGTGCCAAGCAGGCACCCACGAAAGCTGAGAAAATTAAGCTATTGAAACCAATTTCAG
GGAAATTGAGGGCCCAGTGGGAAATGGGCATTGTTCAAGCAGAAGAAGCTGCAAGCATGTCAGTGGAGGAGCGGAAAGCCAAGTTCACCT
TTCTCTATGTGGGGGACCAGCTTCATCTCAACCCTCAAGTAGCCAAGGAGGCTGGCATTGCTGCAGAGTCTTTGGGAGAAATGGCAGAAT
CCTCAGGAGTCAGTGAAGAAGCTGCTGAAAACCCCAAGTCTGTGAGAGAAGAGTGCATTCCCATGAAGAGAAGGCGGAGGGCCAAACTGT
GTAGCTCTGCAGAGACCCTGGAGAGTCACCCCGACATAGGGAAGAGTACTCCTCAAAAGACGGCAGAGGCTGACCCCAGAAGAGGAGTAG
GGTCTCCTCCTGGGAGGAAGAAGACCACAGTCTCCATGCCACGAAGCAGGAAGGGAGATGCAGCATCCCAGTTTTTGGTCTTCTGTCAAA
AACACAGGGATGAGGTGGTAGCTGAGCACCCAGATGCTTCAGGTGAGGAGATTGAAGAGCTGCTCAGGTCACAGTGGAGTCTGCTGAGTG
AGAAGCAGAGAGCACGCTACAACACCAAGTTTGCCCTGGTGGCCCCTGTCCAGGCTGAAGAAGACTCTGGTAATGTAAATGGGAAAAAAA
GAAACCACACAAAGAGGATACAGGACCCTACAGAAGATGCTGAAGCTGAGGACACACCCAGGAAAAGACTCAGGACGGACAAGCACAGTC
TTCGGAAGAGAGACACAATCACTGACAAAACGGCCAGAACAAGCTCTTACAAGGCCATGGAGGCAGCCTCCTCGCTCAAGAGCCAGGCAG
CAACGAAAAATCTGTCTGATGCATGTAAACCACTGAAGAAGCGAAATCGGGCTTCCACGGCAGCATCTTCAGCTCTTGGGTTTAGCAAAA
GTTCATCTCCTTCTGCATCCTTAACTGAGAATGAGGTCTCGGACAGCCCGGGAGACGAGCCCTCGGAGTCCCCATACGAAAGTGCAGACG
AAACACAAACTGAAGTATCTGTCTCATCCAAAAAGTCTGAGCGAGGAGTGACTGCCAAAAAGGAGTATGTGTGCCAGCTGTGTGAGAAGC
CGGGCAGCCTCCTGCTCTGTGAAGGACCCTGCTGCGGAGCTTTCCACCTCGCCTGCCTTGGGCTTTCCCGGAGGCCAGAAGGGAGGTTCA
CCTGCAGCGAGTGTGCCTCAGGGATTCACTCATGTTTCGTGTGTAAAGAGAGCAAGACAGATGTTAAGCGCTGTGTGGTAACTCAGTGTG
GAAAATTTTACCATGAGGCTTGTGTGAAAAAATACCCTCTGACTGTATTTGAGAGCCGAGGTTTCCGCTGCCCCCTCCACAGCTGTGTGA
GCTGCCATGCTTCCAACCCTTCAAACCCAAGGCCGTCAAAAGGTAAAATGATGCGGTGTGTCCGCTGCCCCGTTGCCTATCACAGCGGGG
ATGCTTGTCTGGCAGCAGGATGCTCAGTGATCGCCTCCAACAGCATCATCTGCACTGCCCACTTCACTGCTCGGAAGGGGAAGCGACACC
ACGCCCACGTCAACGTGAGCTGGTGCTTCGTGTGCTCCAAAGGGGGGAGCCTTCTGTGCTGTGAGTCCTGCCCAGCGGCCTTCCACCCTG
ACTGCCTGAACATCGAGATGCCTGACGGCAGCTGGTTCTGCAATGACTGCAGGGCTGGGAAGAAGCTGCACTTCCAGGATATCATTTGGG
TGAAACTTGGGAACTACAGATGGTGGCCGGCAGAAGTTTGCCATCCCAAAAATGTTCCCCCAAATATTCAGAAAATGAAGCACGAGATTG
GAGAATTCCCTGTGTTTTTCTTTGGGTCTAAAGATTATTACTGGACGCATCAGGCGCGAGTGTTCCCGTACATGGAGGGGGACCGGGGCA
GCCGCTACCAGGGGGTCAGAGGGATCGGAAGAGTCTTCAAAAACGGTCAAAAGGCTGAGTTTCAAATTCTGGATAATGTAGACTCAACGG
GAGAGTTGATAGTGAGATTACCCAAAGAAATAACAATTTCAGGCAGTTTCCAGGGCTTCCACCATCAGAAAATCAAGATATCGGAGAACC
GGATATCCCAGCAGTATCTGGCTACCCTTGAAAACAGGAAGCTGAAGAGGGAACTACCCTTTTCATTCCGATCAATTAATACGAGAGAAA
ACCTGTATCTGGTGACAGAAACTCTGGAGACGGTAAAGGAGGAAACCCTGAAAAGCGACCGGCAATATAAATTTTGGAGCCAGATCTCTC
AGGGCCATCTCAGCTATAAACACAAGGGCCAAAGGGAAGTGACCATCCCCCCAAATCGGGTCCTGAGCTATCGAGTAAAGCAGCTTGTCT
TCCCCAACAAGGAGACGATGAGTGCTGGTTTAGATATTCATTTCAGGGGCAAAACAAAATCCTTTCCAGAAGGAAAGTCTTTGGGTTCGG
AGGATTCCAGAAACATGAAGGAGAAGTTGGAGGACATGGAGAGTGTCCTCAAGGACCTGACAGAGGAGAAGAGAAAAGATGTGCTAAACT
CCCTCGCTAAGTGCCTCGGCAAGGAGGATATTCGGCAGGATCTAGAGCAAAGAGTATCTGAGGTCCTGATTTCCGGGGAGCTACACATGG
AGGACCCAGACAAGCCTCTCCTAAGCAGCCTTTTTAATGCTGCTGGGGTCTTGGTAGAAGCGCGTGCAAAAGCCATTCTGGACTTCCTGG
ATGCCCTGCTAGAGCTGTCTGAAGAGCAGCAGTTTGTGGCTGAGGCCCTGGAGAAGGGGACCCTTCCTCTGTTGAAGGACCAGGTGAAAT
CTGTCATGGAGCAGAACTGGGATGAGCTGGCCAGCAGTCCTCCTGACATGGACTATGACCCTGAGGCACGAATTCTCTGTGCGCTGTATG
TTGTTGTCTCTATCCTGCTGGAGCTGGCTGAGGGGCCTACCTCTGTCTCTTCCTAACTACAAAAGCCCTTTCTCCCCACAAGCCTCTGGG
TTTTCCCTTTACCAGTCTGTCCTCACTGCCATCGCCACTACCATCCTGTCACCAGTGGGACCTCTTTAAAACAAGCAGCCAACCATTCTT
TGATGTATCCCATTCGCTCCATGTTAACATCCAAAACCAGCCTGGATTTCATACATGGACTTCTGATTAAAAGTGGCAGGTTGTGCATGT

>99189_99189_16_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000382892_GSDMB_chr17_38068750_ENST00000394179_length(amino acids)=1296AA_BP=963
MGWMEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEGVMQKFNGHDALPFIPADKLKDLTSRVF
NGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNGSPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDS
LLEQGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFF
GDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNP
QVAKEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGKSTPQKTAEADPRRGVGSPPGRKKTTVS
MPRSRKGDAASQFLVFCQKHRDEVVAEHPDASGEEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTE
DAEAEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKRNRASTAASSALGFSKSSSPSASLTENE
VSDSPGDEPSESPYESADETQTEVSVSSKKSERGVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSC
FVCKESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKGKMMRCVRCPVAYHSGDACLAAGCSVIA
SNSIICTAHFTARKGKRHHAHVNVSWCFVCSKGGSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAE
VCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKNGQKAEFQILDNVDSTGELIVRLPKEIT
ISGSFQGFHHQKIKISENRISQQYLATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWSQISQGHLSYKHKGQR
EVTIPPNRVLSYRVKQLVFPNKETMSAGLDIHFRGKTKSFPEGKSLGSEDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIR
QDLEQRVSEVLISGELHMEDPDKPLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQNWDELAS

--------------------------------------------------------------
>99189_99189_17_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000382892_GSDMB_chr17_38068750_ENST00000418519_length(transcript)=4426nt_BP=3195nt
TGGTCTTGAACTCCTGACCTTGTGATCCGCTCGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGTGCCTGTCCTAGAA
CCACTGGTAACTCTTAACTGCTGTCTGCTTTTCTGTGGAGACTGCGGGTTGCAGACACCAGCAGCCCCCTATTGCTGCACGTCAGGTGTC
CTCCACCTCAGTACTGTGGACATCTCGGGCCGCATAGCCCTGTTGCGCGGGCATCCTGTGCGTTGCAGGAGATGCAGCAGCATCCATGAC
CGCAACCCATCAGAGTGTTCTAAGAACGGAAGCATCTGGGCTGGATGGAATTTAGCATCAAGCAGAGTCCCCTTTCTGTTCAGAGTGTTG
TAAAGTGCATAAAGATGAAGCAGGCACCAGAAATCCTCGGCAGTGCCAACGGGAAGACTCCGAGCTGCGAGGTGAACCGCGAGTGTTCTG
TGTTCCTCAGCAAAGCCCAGCTCTCCAGTAGCCTGCAGGAGGGGGTCATGCAGAAGTTTAACGGCCACGACGCCCTGCCCTTTATTCCAG
CCGACAAGCTGAAAGATCTTACTTCCCGGGTGTTTAATGGAGAACCCGGCGCACACGATGCCAAACTGCGTTTTGAGTCCCAGGAAATGA
AAGGGATTGGGACACCCCCTAACACTACCCCTATCAAAAATGGCTCTCCAGAAATTAAGCTGAAAATCACCAAAACATACATGAATGGGA
AGCCTCTCTTTGAATCTTCCATTTGTGGTGACAGTGCTGCTGATGTGTCTCAGTCAGAAGAAAATGGACAAAAACCAGAAAACAAGGCGA
GAAGGAACAGGAAGAGGAGCATAAAATATGACTCCTTGCTGGAGCAGGGCCTTGTCGAAGCAGCTCTTGTGTCTAAGATCTCAAGTCCTT
CAGATAAAAAGATTCCAGCTAAGAAAGAGTCTTGTCCAAACACTGGAAGAGACAAAGACCACCTGTTGAAATACAACGTTGGTGATTTGG
TGTGGTCCAAAGTGTCGGGTTACCCTTGGTGGCCTTGCATGGTTTCTGCAGATCCACTCCTTCACAGCTATACCAAACTTAAAGGTCAGA
AAAAGAGTGCACGCCAGTATCACGTACAGTTCTTTGGTGACGCCCCAGAAAGAGCTTGGATATTTGAGAAGAGCCTCGTAGCTTTTGAAG
GAGAAGGACAGTTTGAAAAATTATGCCAGGAAAGTGCCAAGCAGGCACCCACGAAAGCTGAGAAAATTAAGCTATTGAAACCAATTTCAG
GGAAATTGAGGGCCCAGTGGGAAATGGGCATTGTTCAAGCAGAAGAAGCTGCAAGCATGTCAGTGGAGGAGCGGAAAGCCAAGTTCACCT
TTCTCTATGTGGGGGACCAGCTTCATCTCAACCCTCAAGTAGCCAAGGAGGCTGGCATTGCTGCAGAGTCTTTGGGAGAAATGGCAGAAT
CCTCAGGAGTCAGTGAAGAAGCTGCTGAAAACCCCAAGTCTGTGAGAGAAGAGTGCATTCCCATGAAGAGAAGGCGGAGGGCCAAACTGT
GTAGCTCTGCAGAGACCCTGGAGAGTCACCCCGACATAGGGAAGAGTACTCCTCAAAAGACGGCAGAGGCTGACCCCAGAAGAGGAGTAG
GGTCTCCTCCTGGGAGGAAGAAGACCACAGTCTCCATGCCACGAAGCAGGAAGGGAGATGCAGCATCCCAGTTTTTGGTCTTCTGTCAAA
AACACAGGGATGAGGTGGTAGCTGAGCACCCAGATGCTTCAGGTGAGGAGATTGAAGAGCTGCTCAGGTCACAGTGGAGTCTGCTGAGTG
AGAAGCAGAGAGCACGCTACAACACCAAGTTTGCCCTGGTGGCCCCTGTCCAGGCTGAAGAAGACTCTGGTAATGTAAATGGGAAAAAAA
GAAACCACACAAAGAGGATACAGGACCCTACAGAAGATGCTGAAGCTGAGGACACACCCAGGAAAAGACTCAGGACGGACAAGCACAGTC
TTCGGAAGAGAGACACAATCACTGACAAAACGGCCAGAACAAGCTCTTACAAGGCCATGGAGGCAGCCTCCTCGCTCAAGAGCCAGGCAG
CAACGAAAAATCTGTCTGATGCATGTAAACCACTGAAGAAGCGAAATCGGGCTTCCACGGCAGCATCTTCAGCTCTTGGGTTTAGCAAAA
GTTCATCTCCTTCTGCATCCTTAACTGAGAATGAGGTCTCGGACAGCCCGGGAGACGAGCCCTCGGAGTCCCCATACGAAAGTGCAGACG
AAACACAAACTGAAGTATCTGTCTCATCCAAAAAGTCTGAGCGAGGAGTGACTGCCAAAAAGGAGTATGTGTGCCAGCTGTGTGAGAAGC
CGGGCAGCCTCCTGCTCTGTGAAGGACCCTGCTGCGGAGCTTTCCACCTCGCCTGCCTTGGGCTTTCCCGGAGGCCAGAAGGGAGGTTCA
CCTGCAGCGAGTGTGCCTCAGGGATTCACTCATGTTTCGTGTGTAAAGAGAGCAAGACAGATGTTAAGCGCTGTGTGGTAACTCAGTGTG
GAAAATTTTACCATGAGGCTTGTGTGAAAAAATACCCTCTGACTGTATTTGAGAGCCGAGGTTTCCGCTGCCCCCTCCACAGCTGTGTGA
GCTGCCATGCTTCCAACCCTTCAAACCCAAGGCCGTCAAAAGGTAAAATGATGCGGTGTGTCCGCTGCCCCGTTGCCTATCACAGCGGGG
ATGCTTGTCTGGCAGCAGGATGCTCAGTGATCGCCTCCAACAGCATCATCTGCACTGCCCACTTCACTGCTCGGAAGGGGAAGCGACACC
ACGCCCACGTCAACGTGAGCTGGTGCTTCGTGTGCTCCAAAGGGGGGAGCCTTCTGTGCTGTGAGTCCTGCCCAGCGGCCTTCCACCCTG
ACTGCCTGAACATCGAGATGCCTGACGGCAGCTGGTTCTGCAATGACTGCAGGGCTGGGAAGAAGCTGCACTTCCAGGATATCATTTGGG
TGAAACTTGGGAACTACAGATGGTGGCCGGCAGAAGTTTGCCATCCCAAAAATGTTCCCCCAAATATTCAGAAAATGAAGCACGAGATTG
GAGAATTCCCTGTGTTTTTCTTTGGGTCTAAAGATTATTACTGGACGCATCAGGCGCGAGTGTTCCCGTACATGGAGGGGGACCGGGGCA
GCCGCTACCAGGGGGTCAGAGGGATCGGAAGAGTCTTCAAAAACGGTCAAAAGGCTGAGTTTCAAATTCTGGATAATGTAGACTCAACGG
GAGAGTTGATAGTGAGATTACCCAAAGAAATAACAATTTCAGGCAGTTTCCAGGGCTTCCACCATCAGAAAATCAAGATATCGGAGAACC
GGATATCCCAGCAGTATCTGGCTACCCTTGAAAACAGGAAGCTGAAGAGGGAACTACCCTTTTCATTCCGATCAATTAATACGAGAGAAA
ACCTGTATCTGGTGACAGAAACTCTGGAGACGGTAAAGGAGGAAACCCTGAAAAGCGACCGGCAATATAAATTTTGGAGCCAGATCTCTC
AGGGCCATCTCAGCTATAAACACAAGGGCCAAAGGGAAGTGACCATCCCCCCAAATCGGGTCCTGAGCTATCGAGTAAAGCAGCTTGTCT
TCCCCAACAAGGAGACGATGAATATTCATTTCAGGGGCAAAACAAAATCCTTTCCAGAAGAGAAGGATGGTGCTTCATCCTGTTTAGGAA
AGTCTTTGGGTTCGGAGGATTCCAGAAACATGAAGGAGAAGTTGGAGGACATGGAGAGTGTCCTCAAGGACCTGACAGAGGAGAAGAGAA
AAGATGTGCTAAACTCCCTCGCTAAGTGCCTCGGCAAGGAGGATATTCGGCAGGATCTAGAGCAAAGAGTATCTGAGGTCCTGATTTCCG
GGGAGCTACACATGGAGGACCCAGACAAGCCTCTCCTAAGCAGCCTTTTTAATGCTGCTGGGGTCTTGGTAGAAGCGCGTGCAAAAGCCA
TTCTGGACTTCCTGGATGCCCTGCTAGAGCTGTCTGAAGAGCAGCAGTTTGTGGCTGAGGCCCTGGAGAAGGGGACCCTTCCTCTGTTGA
AGGACCAGGTGAAATCTGTCATGGAGCAGAACTGGGATGAGCTGGCCAGCAGTCCTCCTGACATGGACTATGACCCTGAGGCACGAATTC
TCTGTGCGCTGTATGTTGTTGTCTCTATCCTGCTGGAGCTGGCTGAGGGGCCTACCTCTGTCTCTTCCTAACTACAAAAGCCCTTTCTCC
CCACAAGCCTCTGGGTTTTCCCTTTACCAGTCTGTCCTCACTGCCATCGCCACTACCATCCTGTCACCAGTGGGACCTCTTTAAAACAAG
CAGCCAACCATTCTTTGATGTATCCCATTCGCTCCATGTTAACATCCAAAACCAGCCTGGATTTCATACATGGACTTCTGATTAAAAGTG

>99189_99189_17_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000382892_GSDMB_chr17_38068750_ENST00000418519_length(amino acids)=1301AA_BP=963
MGWMEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEGVMQKFNGHDALPFIPADKLKDLTSRVF
NGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNGSPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDS
LLEQGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFF
GDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNP
QVAKEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGKSTPQKTAEADPRRGVGSPPGRKKTTVS
MPRSRKGDAASQFLVFCQKHRDEVVAEHPDASGEEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTE
DAEAEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKRNRASTAASSALGFSKSSSPSASLTENE
VSDSPGDEPSESPYESADETQTEVSVSSKKSERGVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSC
FVCKESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKGKMMRCVRCPVAYHSGDACLAAGCSVIA
SNSIICTAHFTARKGKRHHAHVNVSWCFVCSKGGSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAE
VCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKNGQKAEFQILDNVDSTGELIVRLPKEIT
ISGSFQGFHHQKIKISENRISQQYLATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWSQISQGHLSYKHKGQR
EVTIPPNRVLSYRVKQLVFPNKETMNIHFRGKTKSFPEEKDGASSCLGKSLGSEDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLG
KEDIRQDLEQRVSEVLISGELHMEDPDKPLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQNW

--------------------------------------------------------------
>99189_99189_18_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000382892_GSDMB_chr17_38068750_ENST00000520542_length(transcript)=4399nt_BP=3195nt
TGGTCTTGAACTCCTGACCTTGTGATCCGCTCGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGTGCCTGTCCTAGAA
CCACTGGTAACTCTTAACTGCTGTCTGCTTTTCTGTGGAGACTGCGGGTTGCAGACACCAGCAGCCCCCTATTGCTGCACGTCAGGTGTC
CTCCACCTCAGTACTGTGGACATCTCGGGCCGCATAGCCCTGTTGCGCGGGCATCCTGTGCGTTGCAGGAGATGCAGCAGCATCCATGAC
CGCAACCCATCAGAGTGTTCTAAGAACGGAAGCATCTGGGCTGGATGGAATTTAGCATCAAGCAGAGTCCCCTTTCTGTTCAGAGTGTTG
TAAAGTGCATAAAGATGAAGCAGGCACCAGAAATCCTCGGCAGTGCCAACGGGAAGACTCCGAGCTGCGAGGTGAACCGCGAGTGTTCTG
TGTTCCTCAGCAAAGCCCAGCTCTCCAGTAGCCTGCAGGAGGGGGTCATGCAGAAGTTTAACGGCCACGACGCCCTGCCCTTTATTCCAG
CCGACAAGCTGAAAGATCTTACTTCCCGGGTGTTTAATGGAGAACCCGGCGCACACGATGCCAAACTGCGTTTTGAGTCCCAGGAAATGA
AAGGGATTGGGACACCCCCTAACACTACCCCTATCAAAAATGGCTCTCCAGAAATTAAGCTGAAAATCACCAAAACATACATGAATGGGA
AGCCTCTCTTTGAATCTTCCATTTGTGGTGACAGTGCTGCTGATGTGTCTCAGTCAGAAGAAAATGGACAAAAACCAGAAAACAAGGCGA
GAAGGAACAGGAAGAGGAGCATAAAATATGACTCCTTGCTGGAGCAGGGCCTTGTCGAAGCAGCTCTTGTGTCTAAGATCTCAAGTCCTT
CAGATAAAAAGATTCCAGCTAAGAAAGAGTCTTGTCCAAACACTGGAAGAGACAAAGACCACCTGTTGAAATACAACGTTGGTGATTTGG
TGTGGTCCAAAGTGTCGGGTTACCCTTGGTGGCCTTGCATGGTTTCTGCAGATCCACTCCTTCACAGCTATACCAAACTTAAAGGTCAGA
AAAAGAGTGCACGCCAGTATCACGTACAGTTCTTTGGTGACGCCCCAGAAAGAGCTTGGATATTTGAGAAGAGCCTCGTAGCTTTTGAAG
GAGAAGGACAGTTTGAAAAATTATGCCAGGAAAGTGCCAAGCAGGCACCCACGAAAGCTGAGAAAATTAAGCTATTGAAACCAATTTCAG
GGAAATTGAGGGCCCAGTGGGAAATGGGCATTGTTCAAGCAGAAGAAGCTGCAAGCATGTCAGTGGAGGAGCGGAAAGCCAAGTTCACCT
TTCTCTATGTGGGGGACCAGCTTCATCTCAACCCTCAAGTAGCCAAGGAGGCTGGCATTGCTGCAGAGTCTTTGGGAGAAATGGCAGAAT
CCTCAGGAGTCAGTGAAGAAGCTGCTGAAAACCCCAAGTCTGTGAGAGAAGAGTGCATTCCCATGAAGAGAAGGCGGAGGGCCAAACTGT
GTAGCTCTGCAGAGACCCTGGAGAGTCACCCCGACATAGGGAAGAGTACTCCTCAAAAGACGGCAGAGGCTGACCCCAGAAGAGGAGTAG
GGTCTCCTCCTGGGAGGAAGAAGACCACAGTCTCCATGCCACGAAGCAGGAAGGGAGATGCAGCATCCCAGTTTTTGGTCTTCTGTCAAA
AACACAGGGATGAGGTGGTAGCTGAGCACCCAGATGCTTCAGGTGAGGAGATTGAAGAGCTGCTCAGGTCACAGTGGAGTCTGCTGAGTG
AGAAGCAGAGAGCACGCTACAACACCAAGTTTGCCCTGGTGGCCCCTGTCCAGGCTGAAGAAGACTCTGGTAATGTAAATGGGAAAAAAA
GAAACCACACAAAGAGGATACAGGACCCTACAGAAGATGCTGAAGCTGAGGACACACCCAGGAAAAGACTCAGGACGGACAAGCACAGTC
TTCGGAAGAGAGACACAATCACTGACAAAACGGCCAGAACAAGCTCTTACAAGGCCATGGAGGCAGCCTCCTCGCTCAAGAGCCAGGCAG
CAACGAAAAATCTGTCTGATGCATGTAAACCACTGAAGAAGCGAAATCGGGCTTCCACGGCAGCATCTTCAGCTCTTGGGTTTAGCAAAA
GTTCATCTCCTTCTGCATCCTTAACTGAGAATGAGGTCTCGGACAGCCCGGGAGACGAGCCCTCGGAGTCCCCATACGAAAGTGCAGACG
AAACACAAACTGAAGTATCTGTCTCATCCAAAAAGTCTGAGCGAGGAGTGACTGCCAAAAAGGAGTATGTGTGCCAGCTGTGTGAGAAGC
CGGGCAGCCTCCTGCTCTGTGAAGGACCCTGCTGCGGAGCTTTCCACCTCGCCTGCCTTGGGCTTTCCCGGAGGCCAGAAGGGAGGTTCA
CCTGCAGCGAGTGTGCCTCAGGGATTCACTCATGTTTCGTGTGTAAAGAGAGCAAGACAGATGTTAAGCGCTGTGTGGTAACTCAGTGTG
GAAAATTTTACCATGAGGCTTGTGTGAAAAAATACCCTCTGACTGTATTTGAGAGCCGAGGTTTCCGCTGCCCCCTCCACAGCTGTGTGA
GCTGCCATGCTTCCAACCCTTCAAACCCAAGGCCGTCAAAAGGTAAAATGATGCGGTGTGTCCGCTGCCCCGTTGCCTATCACAGCGGGG
ATGCTTGTCTGGCAGCAGGATGCTCAGTGATCGCCTCCAACAGCATCATCTGCACTGCCCACTTCACTGCTCGGAAGGGGAAGCGACACC
ACGCCCACGTCAACGTGAGCTGGTGCTTCGTGTGCTCCAAAGGGGGGAGCCTTCTGTGCTGTGAGTCCTGCCCAGCGGCCTTCCACCCTG
ACTGCCTGAACATCGAGATGCCTGACGGCAGCTGGTTCTGCAATGACTGCAGGGCTGGGAAGAAGCTGCACTTCCAGGATATCATTTGGG
TGAAACTTGGGAACTACAGATGGTGGCCGGCAGAAGTTTGCCATCCCAAAAATGTTCCCCCAAATATTCAGAAAATGAAGCACGAGATTG
GAGAATTCCCTGTGTTTTTCTTTGGGTCTAAAGATTATTACTGGACGCATCAGGCGCGAGTGTTCCCGTACATGGAGGGGGACCGGGGCA
GCCGCTACCAGGGGGTCAGAGGGATCGGAAGAGTCTTCAAAAACGGTCAAAAGGCTGAGTTTCAAATTCTGGATAATGTAGACTCAACGG
GAGAGTTGATAGTGAGATTACCCAAAGAAATAACAATTTCAGGCAGTTTCCAGGGCTTCCACCATCAGAAAATCAAGATATCGGAGAACC
GGATATCCCAGCAGTATCTGGCTACCCTTGAAAACAGGAAGCTGAAGAGGGAACTACCCTTTTCATTCCGATCAATTAATACGAGAGAAA
ACCTGTATCTGGTGACAGAAACTCTGGAGACGGTAAAGGAGGAAACCCTGAAAAGCGACCGGCAATATAAATTTTGGAGCCAGATCTCTC
AGGGCCATCTCAGCTATAAACACAAGGGCCAAAGGGAAGTGACCATCCCCCCAAATCGGGTCCTGAGCTATCGAGTAAAGCAGCTTGTCT
TCCCCAACAAGGAGACGATGAATATTCATTTCAGGGGCAAAACAAAATCCTTTCCAGAAGGAAAGTCTTTGGGTTCGGAGGATTCCAGAA
ACATGAAGGAGAAGTTGGAGGACATGGAGAGTGTCCTCAAGGACCTGACAGAGGAGAAGAGAAAAGATGTGCTAAACTCCCTCGCTAAGT
GCCTCGGCAAGGAGGATATTCGGCAGGATCTAGAGCAAAGAGTATCTGAGGTCCTGATTTCCGGGGAGCTACACATGGAGGACCCAGACA
AGCCTCTCCTAAGCAGCCTTTTTAATGCTGCTGGGGTCTTGGTAGAAGCGCGTGCAAAAGCCATTCTGGACTTCCTGGATGCCCTGCTAG
AGCTGTCTGAAGAGCAGCAGTTTGTGGCTGAGGCCCTGGAGAAGGGGACCCTTCCTCTGTTGAAGGACCAGGTGAAATCTGTCATGGAGC
AGAACTGGGATGAGCTGGCCAGCAGTCCTCCTGACATGGACTATGACCCTGAGGCACGAATTCTCTGTGCGCTGTATGTTGTTGTCTCTA
TCCTGCTGGAGCTGGCTGAGGGGCCTACCTCTGTCTCTTCCTAACTACAAAAGCCCTTTCTCCCCACAAGCCTCTGGGTTTTCCCTTTAC
CAGTCTGTCCTCACTGCCATCGCCACTACCATCCTGTCACCAGTGGGACCTCTTTAAAACAAGCAGCCAACCATTCTTTGATGTATCCCA

>99189_99189_18_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000382892_GSDMB_chr17_38068750_ENST00000520542_length(amino acids)=1292AA_BP=963
MGWMEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEGVMQKFNGHDALPFIPADKLKDLTSRVF
NGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNGSPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDS
LLEQGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFF
GDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNP
QVAKEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGKSTPQKTAEADPRRGVGSPPGRKKTTVS
MPRSRKGDAASQFLVFCQKHRDEVVAEHPDASGEEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTE
DAEAEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKRNRASTAASSALGFSKSSSPSASLTENE
VSDSPGDEPSESPYESADETQTEVSVSSKKSERGVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSC
FVCKESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKGKMMRCVRCPVAYHSGDACLAAGCSVIA
SNSIICTAHFTARKGKRHHAHVNVSWCFVCSKGGSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAE
VCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKNGQKAEFQILDNVDSTGELIVRLPKEIT
ISGSFQGFHHQKIKISENRISQQYLATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWSQISQGHLSYKHKGQR
EVTIPPNRVLSYRVKQLVFPNKETMNIHFRGKTKSFPEGKSLGSEDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLE
QRVSEVLISGELHMEDPDKPLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQNWDELASSPPD

--------------------------------------------------------------
>99189_99189_19_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000382895_GSDMB_chr17_38068750_ENST00000309481_length(transcript)=4506nt_BP=3312nt
GCATGAGCCACCGTGCCTGTCCTAGAACCACTGGTAACTCTTAACTGAGACAAGATTTCGCCATGTTGCCCAGGCTGGTCTCGAACTTCT
GAGCTCAAGCGATCTACCTGCCTCGTCCTCCCAAAGTGTTGGAATTGCAGGTGTGAGCCACTGCACCCGGCCCTTGCCTCATGTTTGAAT
GATAATTTACCTGGGCATAAAATTCTGGACACTTGTGGTGGCACGAGCTGTCTGCTTTTCTGTGGAGACTGCGGGTTGCAGACACCAGCA
GCCCCCTATTGCTGCACGTCAGGTGTCCTCCACCTCAGTACTGTGGACATCTCGGGCCGCATAGCCCTGTTGCGCGGGCATCCTGTGCGT
TGCAGGAGATGCAGCAGCATCCATGACCGCAACCCATCAGAGTGTTCTAAGAACGGAAGCATCTGGGCTGGATGGAATTTAGCATCAAGC
AGAGTCCCCTTTCTGTTCAGAGTGTTGTAAAGTGCATAAAGATGAAGCAGGCACCAGAAATCCTCGGCAGTGCCAACGGGAAGACTCCGA
GCTGCGAGGTGAACCGCGAGTGTTCTGTGTTCCTCAGCAAAGCCCAGCTCTCCAGTAGCCTGCAGGAGGGGGTCATGCAGAAGTTTAACG
GCCACGACGCCCTGCCCTTTATTCCAGCCGACAAGCTGAAAGATCTTACTTCCCGGGTGTTTAATGGAGAACCCGGCGCACACGATGCCA
AACTGCGTTTTGAGTCCCAGGAAATGAAAGGGATTGGGACACCCCCTAACACTACCCCTATCAAAAATGGCTCTCCAGAAATTAAGCTGA
AAATCACCAAAACATACATGAATGGGAAGCCTCTCTTTGAATCTTCCATTTGTGGTGACAGTGCTGCTGATGTGTCTCAGTCAGAAGAAA
ATGGACAAAAACCAGAAAACAAGGCGAGAAGGAACAGGAAGAGGAGCATAAAATATGACTCCTTGCTGGAGCAGGGCCTTGTCGAAGCAG
CTCTTGTGTCTAAGATCTCAAGTCCTTCAGATAAAAAGATTCCAGCTAAGAAAGAGTCTTGTCCAAACACTGGAAGAGACAAAGACCACC
TGTTGAAATACAACGTTGGTGATTTGGTGTGGTCCAAAGTGTCGGGTTACCCTTGGTGGCCTTGCATGGTTTCTGCAGATCCACTCCTTC
ACAGCTATACCAAACTTAAAGGTCAGAAAAAGAGTGCACGCCAGTATCACGTACAGTTCTTTGGTGACGCCCCAGAAAGAGCTTGGATAT
TTGAGAAGAGCCTCGTAGCTTTTGAAGGAGAAGGACAGTTTGAAAAATTATGCCAGGAAAGTGCCAAGCAGGCACCCACGAAAGCTGAGA
AAATTAAGCTATTGAAACCAATTTCAGGGAAATTGAGGGCCCAGTGGGAAATGGGCATTGTTCAAGCAGAAGAAGCTGCAAGCATGTCAG
TGGAGGAGCGGAAAGCCAAGTTCACCTTTCTCTATGTGGGGGACCAGCTTCATCTCAACCCTCAAGTAGCCAAGGAGGCTGGCATTGCTG
CAGAGTCTTTGGGAGAAATGGCAGAATCCTCAGGAGTCAGTGAAGAAGCTGCTGAAAACCCCAAGTCTGTGAGAGAAGAGTGCATTCCCA
TGAAGAGAAGGCGGAGGGCCAAACTGTGTAGCTCTGCAGAGACCCTGGAGAGTCACCCCGACATAGGGAAGAGTACTCCTCAAAAGACGG
CAGAGGCTGACCCCAGAAGAGGAGTAGGGTCTCCTCCTGGGAGGAAGAAGACCACAGTCTCCATGCCACGAAGCAGGAAGGGAGATGCAG
CATCCCAGTTTTTGGTCTTCTGTCAAAAACACAGGGATGAGGTGGTAGCTGAGCACCCAGATGCTTCAGGTGAGGAGATTGAAGAGCTGC
TCAGGTCACAGTGGAGTCTGCTGAGTGAGAAGCAGAGAGCACGCTACAACACCAAGTTTGCCCTGGTGGCCCCTGTCCAGGCTGAAGAAG
ACTCTGGTAATGTAAATGGGAAAAAAAGAAACCACACAAAGAGGATACAGGACCCTACAGAAGATGCTGAAGCTGAGGACACACCCAGGA
AAAGACTCAGGACGGACAAGCACAGTCTTCGGAAGAGAGACACAATCACTGACAAAACGGCCAGAACAAGCTCTTACAAGGCCATGGAGG
CAGCCTCCTCGCTCAAGAGCCAGGCAGCAACGAAAAATCTGTCTGATGCATGTAAACCACTGAAGAAGCGAAATCGGGCTTCCACGGCAG
CATCTTCAGCTCTTGGGTTTAGCAAAAGTTCATCTCCTTCTGCATCCTTAACTGAGAATGAGGTCTCGGACAGCCCGGGAGACGAGCCCT
CGGAGTCCCCATACGAAAGTGCAGACGAAACACAAACTGAAGTATCTGTCTCATCCAAAAAGTCTGAGCGAGGAGTGACTGCCAAAAAGG
AGTATGTGTGCCAGCTGTGTGAGAAGCCGGGCAGCCTCCTGCTCTGTGAAGGACCCTGCTGCGGAGCTTTCCACCTCGCCTGCCTTGGGC
TTTCCCGGAGGCCAGAAGGGAGGTTCACCTGCAGCGAGTGTGCCTCAGGGATTCACTCATGTTTCGTGTGTAAAGAGAGCAAGACAGATG
TTAAGCGCTGTGTGGTAACTCAGTGTGGAAAATTTTACCATGAGGCTTGTGTGAAAAAATACCCTCTGACTGTATTTGAGAGCCGAGGTT
TCCGCTGCCCCCTCCACAGCTGTGTGAGCTGCCATGCTTCCAACCCTTCAAACCCAAGGCCGTCAAAAGGTAAAATGATGCGGTGTGTCC
GCTGCCCCGTTGCCTATCACAGCGGGGATGCTTGTCTGGCAGCAGGATGCTCAGTGATCGCCTCCAACAGCATCATCTGCACTGCCCACT
TCACTGCTCGGAAGGGGAAGCGACACCACGCCCACGTCAACGTGAGCTGGTGCTTCGTGTGCTCCAAAGGGGGGAGCCTTCTGTGCTGTG
AGTCCTGCCCAGCGGCCTTCCACCCTGACTGCCTGAACATCGAGATGCCTGACGGCAGCTGGTTCTGCAATGACTGCAGGGCTGGGAAGA
AGCTGCACTTCCAGGATATCATTTGGGTGAAACTTGGGAACTACAGATGGTGGCCGGCAGAAGTTTGCCATCCCAAAAATGTTCCCCCAA
ATATTCAGAAAATGAAGCACGAGATTGGAGAATTCCCTGTGTTTTTCTTTGGGTCTAAAGATTATTACTGGACGCATCAGGCGCGAGTGT
TCCCGTACATGGAGGGGGACCGGGGCAGCCGCTACCAGGGGGTCAGAGGGATCGGAAGAGTCTTCAAAAACGGTCAAAAGGCTGAGTTTC
AAATTCTGGATAATGTAGACTCAACGGGAGAGTTGATAGTGAGATTACCCAAAGAAATAACAATTTCAGGCAGTTTCCAGGGCTTCCACC
ATCAGAAAATCAAGATATCGGAGAACCGGATATCCCAGCAGTATCTGGCTACCCTTGAAAACAGGAAGCTGAAGAGGGAACTACCCTTTT
CATTCCGATCAATTAATACGAGAGAAAACCTGTATCTGGTGACAGAAACTCTGGAGACGGTAAAGGAGGAAACCCTGAAAAGCGACCGGC
AATATAAATTTTGGAGCCAGATCTCTCAGGGCCATCTCAGCTATAAACACAAGGGCCAAAGGGAAGTGACCATCCCCCCAAATCGGGTCC
TGAGCTATCGAGTAAAGCAGCTTGTCTTCCCCAACAAGGAGACGATGAAGAAGGATGGTGCTTCATCCTGTTTAGGAAAGTCTTTGGGTT
CGGAGGATTCCAGAAACATGAAGGAGAAGTTGGAGGACATGGAGAGTGTCCTCAAGGACCTGACAGAGGAGAAGAGAAAAGATGTGCTAA
ACTCCCTCGCTAAGTGCCTCGGCAAGGAGGATATTCGGCAGGATCTAGAGCAAAGAGTATCTGAGGTCCTGATTTCCGGGGAGCTACACA
TGGAGGACCCAGACAAGCCTCTCCTAAGCAGCCTTTTTAATGCTGCTGGGGTCTTGGTAGAAGCGCGTGCAAAAGCCATTCTGGACTTCC
TGGATGCCCTGCTAGAGCTGTCTGAAGAGCAGCAGTTTGTGGCTGAGGCCCTGGAGAAGGGGACCCTTCCTCTGTTGAAGGACCAGGTGA
AATCTGTCATGGAGCAGAACTGGGATGAGCTGGCCAGCAGTCCTCCTGACATGGACTATGACCCTGAGGCACGAATTCTCTGTGCGCTGT
ATGTTGTTGTCTCTATCCTGCTGGAGCTGGCTGAGGGGCCTACCTCTGTCTCTTCCTAACTACAAAAGCCCTTTCTCCCCACAAGCCTCT
GGGTTTTCCCTTTACCAGTCTGTCCTCACTGCCATCGCCACTACCATCCTGTCACCAGTGGGACCTCTTTAAAACAAGCAGCCAACCATT
CTTTGATGTATCCCATTCGCTCCATGTTAACATCCAAAACCAGCCTGGATTTCATACATGGACTTCTGATTAAAAGTGGCAGGTTGTGCA

>99189_99189_19_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000382895_GSDMB_chr17_38068750_ENST00000309481_length(amino acids)=1288AA_BP=963
MGWMEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEGVMQKFNGHDALPFIPADKLKDLTSRVF
NGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNGSPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDS
LLEQGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFF
GDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNP
QVAKEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGKSTPQKTAEADPRRGVGSPPGRKKTTVS
MPRSRKGDAASQFLVFCQKHRDEVVAEHPDASGEEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTE
DAEAEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKRNRASTAASSALGFSKSSSPSASLTENE
VSDSPGDEPSESPYESADETQTEVSVSSKKSERGVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSC
FVCKESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKGKMMRCVRCPVAYHSGDACLAAGCSVIA
SNSIICTAHFTARKGKRHHAHVNVSWCFVCSKGGSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAE
VCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKNGQKAEFQILDNVDSTGELIVRLPKEIT
ISGSFQGFHHQKIKISENRISQQYLATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWSQISQGHLSYKHKGQR
EVTIPPNRVLSYRVKQLVFPNKETMKKDGASSCLGKSLGSEDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVS
EVLISGELHMEDPDKPLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQNWDELASSPPDMDYD

--------------------------------------------------------------
>99189_99189_20_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000382895_GSDMB_chr17_38068750_ENST00000360317_length(transcript)=4545nt_BP=3312nt
GCATGAGCCACCGTGCCTGTCCTAGAACCACTGGTAACTCTTAACTGAGACAAGATTTCGCCATGTTGCCCAGGCTGGTCTCGAACTTCT
GAGCTCAAGCGATCTACCTGCCTCGTCCTCCCAAAGTGTTGGAATTGCAGGTGTGAGCCACTGCACCCGGCCCTTGCCTCATGTTTGAAT
GATAATTTACCTGGGCATAAAATTCTGGACACTTGTGGTGGCACGAGCTGTCTGCTTTTCTGTGGAGACTGCGGGTTGCAGACACCAGCA
GCCCCCTATTGCTGCACGTCAGGTGTCCTCCACCTCAGTACTGTGGACATCTCGGGCCGCATAGCCCTGTTGCGCGGGCATCCTGTGCGT
TGCAGGAGATGCAGCAGCATCCATGACCGCAACCCATCAGAGTGTTCTAAGAACGGAAGCATCTGGGCTGGATGGAATTTAGCATCAAGC
AGAGTCCCCTTTCTGTTCAGAGTGTTGTAAAGTGCATAAAGATGAAGCAGGCACCAGAAATCCTCGGCAGTGCCAACGGGAAGACTCCGA
GCTGCGAGGTGAACCGCGAGTGTTCTGTGTTCCTCAGCAAAGCCCAGCTCTCCAGTAGCCTGCAGGAGGGGGTCATGCAGAAGTTTAACG
GCCACGACGCCCTGCCCTTTATTCCAGCCGACAAGCTGAAAGATCTTACTTCCCGGGTGTTTAATGGAGAACCCGGCGCACACGATGCCA
AACTGCGTTTTGAGTCCCAGGAAATGAAAGGGATTGGGACACCCCCTAACACTACCCCTATCAAAAATGGCTCTCCAGAAATTAAGCTGA
AAATCACCAAAACATACATGAATGGGAAGCCTCTCTTTGAATCTTCCATTTGTGGTGACAGTGCTGCTGATGTGTCTCAGTCAGAAGAAA
ATGGACAAAAACCAGAAAACAAGGCGAGAAGGAACAGGAAGAGGAGCATAAAATATGACTCCTTGCTGGAGCAGGGCCTTGTCGAAGCAG
CTCTTGTGTCTAAGATCTCAAGTCCTTCAGATAAAAAGATTCCAGCTAAGAAAGAGTCTTGTCCAAACACTGGAAGAGACAAAGACCACC
TGTTGAAATACAACGTTGGTGATTTGGTGTGGTCCAAAGTGTCGGGTTACCCTTGGTGGCCTTGCATGGTTTCTGCAGATCCACTCCTTC
ACAGCTATACCAAACTTAAAGGTCAGAAAAAGAGTGCACGCCAGTATCACGTACAGTTCTTTGGTGACGCCCCAGAAAGAGCTTGGATAT
TTGAGAAGAGCCTCGTAGCTTTTGAAGGAGAAGGACAGTTTGAAAAATTATGCCAGGAAAGTGCCAAGCAGGCACCCACGAAAGCTGAGA
AAATTAAGCTATTGAAACCAATTTCAGGGAAATTGAGGGCCCAGTGGGAAATGGGCATTGTTCAAGCAGAAGAAGCTGCAAGCATGTCAG
TGGAGGAGCGGAAAGCCAAGTTCACCTTTCTCTATGTGGGGGACCAGCTTCATCTCAACCCTCAAGTAGCCAAGGAGGCTGGCATTGCTG
CAGAGTCTTTGGGAGAAATGGCAGAATCCTCAGGAGTCAGTGAAGAAGCTGCTGAAAACCCCAAGTCTGTGAGAGAAGAGTGCATTCCCA
TGAAGAGAAGGCGGAGGGCCAAACTGTGTAGCTCTGCAGAGACCCTGGAGAGTCACCCCGACATAGGGAAGAGTACTCCTCAAAAGACGG
CAGAGGCTGACCCCAGAAGAGGAGTAGGGTCTCCTCCTGGGAGGAAGAAGACCACAGTCTCCATGCCACGAAGCAGGAAGGGAGATGCAG
CATCCCAGTTTTTGGTCTTCTGTCAAAAACACAGGGATGAGGTGGTAGCTGAGCACCCAGATGCTTCAGGTGAGGAGATTGAAGAGCTGC
TCAGGTCACAGTGGAGTCTGCTGAGTGAGAAGCAGAGAGCACGCTACAACACCAAGTTTGCCCTGGTGGCCCCTGTCCAGGCTGAAGAAG
ACTCTGGTAATGTAAATGGGAAAAAAAGAAACCACACAAAGAGGATACAGGACCCTACAGAAGATGCTGAAGCTGAGGACACACCCAGGA
AAAGACTCAGGACGGACAAGCACAGTCTTCGGAAGAGAGACACAATCACTGACAAAACGGCCAGAACAAGCTCTTACAAGGCCATGGAGG
CAGCCTCCTCGCTCAAGAGCCAGGCAGCAACGAAAAATCTGTCTGATGCATGTAAACCACTGAAGAAGCGAAATCGGGCTTCCACGGCAG
CATCTTCAGCTCTTGGGTTTAGCAAAAGTTCATCTCCTTCTGCATCCTTAACTGAGAATGAGGTCTCGGACAGCCCGGGAGACGAGCCCT
CGGAGTCCCCATACGAAAGTGCAGACGAAACACAAACTGAAGTATCTGTCTCATCCAAAAAGTCTGAGCGAGGAGTGACTGCCAAAAAGG
AGTATGTGTGCCAGCTGTGTGAGAAGCCGGGCAGCCTCCTGCTCTGTGAAGGACCCTGCTGCGGAGCTTTCCACCTCGCCTGCCTTGGGC
TTTCCCGGAGGCCAGAAGGGAGGTTCACCTGCAGCGAGTGTGCCTCAGGGATTCACTCATGTTTCGTGTGTAAAGAGAGCAAGACAGATG
TTAAGCGCTGTGTGGTAACTCAGTGTGGAAAATTTTACCATGAGGCTTGTGTGAAAAAATACCCTCTGACTGTATTTGAGAGCCGAGGTT
TCCGCTGCCCCCTCCACAGCTGTGTGAGCTGCCATGCTTCCAACCCTTCAAACCCAAGGCCGTCAAAAGGTAAAATGATGCGGTGTGTCC
GCTGCCCCGTTGCCTATCACAGCGGGGATGCTTGTCTGGCAGCAGGATGCTCAGTGATCGCCTCCAACAGCATCATCTGCACTGCCCACT
TCACTGCTCGGAAGGGGAAGCGACACCACGCCCACGTCAACGTGAGCTGGTGCTTCGTGTGCTCCAAAGGGGGGAGCCTTCTGTGCTGTG
AGTCCTGCCCAGCGGCCTTCCACCCTGACTGCCTGAACATCGAGATGCCTGACGGCAGCTGGTTCTGCAATGACTGCAGGGCTGGGAAGA
AGCTGCACTTCCAGGATATCATTTGGGTGAAACTTGGGAACTACAGATGGTGGCCGGCAGAAGTTTGCCATCCCAAAAATGTTCCCCCAA
ATATTCAGAAAATGAAGCACGAGATTGGAGAATTCCCTGTGTTTTTCTTTGGGTCTAAAGATTATTACTGGACGCATCAGGCGCGAGTGT
TCCCGTACATGGAGGGGGACCGGGGCAGCCGCTACCAGGGGGTCAGAGGGATCGGAAGAGTCTTCAAAAACGGTCAAAAGGCTGAGTTTC
AAATTCTGGATAATGTAGACTCAACGGGAGAGTTGATAGTGAGATTACCCAAAGAAATAACAATTTCAGGCAGTTTCCAGGGCTTCCACC
ATCAGAAAATCAAGATATCGGAGAACCGGATATCCCAGCAGTATCTGGCTACCCTTGAAAACAGGAAGCTGAAGAGGGAACTACCCTTTT
CATTCCGATCAATTAATACGAGAGAAAACCTGTATCTGGTGACAGAAACTCTGGAGACGGTAAAGGAGGAAACCCTGAAAAGCGACCGGC
AATATAAATTTTGGAGCCAGATCTCTCAGGGCCATCTCAGCTATAAACACAAGGGCCAAAGGGAAGTGACCATCCCCCCAAATCGGGTCC
TGAGCTATCGAGTAAAGCAGCTTGTCTTCCCCAACAAGGAGACGATGAATATTCATTTCAGGGGCAAAACAAAATCCTTTCCAGAAGAGA
AGGATGGTGCTTCATCCTGTTTAGGAAAGTCTTTGGGTTCGGAGGATTCCAGAAACATGAAGGAGAAGTTGGAGGACATGGAGAGTGTCC
TCAAGGACCTGACAGAGGAGAAGAGAAAAGATGTGCTAAACTCCCTCGCTAAGTGCCTCGGCAAGGAGGATATTCGGCAGGATCTAGAGC
AAAGAGTATCTGAGGTCCTGATTTCCGGGGAGCTACACATGGAGGACCCAGACAAGCCTCTCCTAAGCAGCCTTTTTAATGCTGCTGGGG
TCTTGGTAGAAGCGCGTGCAAAAGCCATTCTGGACTTCCTGGATGCCCTGCTAGAGCTGTCTGAAGAGCAGCAGTTTGTGGCTGAGGCCC
TGGAGAAGGGGACCCTTCCTCTGTTGAAGGACCAGGTGAAATCTGTCATGGAGCAGAACTGGGATGAGCTGGCCAGCAGTCCTCCTGACA
TGGACTATGACCCTGAGGCACGAATTCTCTGTGCGCTGTATGTTGTTGTCTCTATCCTGCTGGAGCTGGCTGAGGGGCCTACCTCTGTCT
CTTCCTAACTACAAAAGCCCTTTCTCCCCACAAGCCTCTGGGTTTTCCCTTTACCAGTCTGTCCTCACTGCCATCGCCACTACCATCCTG
TCACCAGTGGGACCTCTTTAAAACAAGCAGCCAACCATTCTTTGATGTATCCCATTCGCTCCATGTTAACATCCAAAACCAGCCTGGATT

>99189_99189_20_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000382895_GSDMB_chr17_38068750_ENST00000360317_length(amino acids)=1301AA_BP=963
MGWMEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEGVMQKFNGHDALPFIPADKLKDLTSRVF
NGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNGSPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDS
LLEQGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFF
GDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNP
QVAKEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGKSTPQKTAEADPRRGVGSPPGRKKTTVS
MPRSRKGDAASQFLVFCQKHRDEVVAEHPDASGEEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTE
DAEAEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKRNRASTAASSALGFSKSSSPSASLTENE
VSDSPGDEPSESPYESADETQTEVSVSSKKSERGVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSC
FVCKESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKGKMMRCVRCPVAYHSGDACLAAGCSVIA
SNSIICTAHFTARKGKRHHAHVNVSWCFVCSKGGSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAE
VCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKNGQKAEFQILDNVDSTGELIVRLPKEIT
ISGSFQGFHHQKIKISENRISQQYLATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWSQISQGHLSYKHKGQR
EVTIPPNRVLSYRVKQLVFPNKETMNIHFRGKTKSFPEEKDGASSCLGKSLGSEDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLG
KEDIRQDLEQRVSEVLISGELHMEDPDKPLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQNW

--------------------------------------------------------------
>99189_99189_21_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000382895_GSDMB_chr17_38068750_ENST00000394175_length(transcript)=4479nt_BP=3312nt
GCATGAGCCACCGTGCCTGTCCTAGAACCACTGGTAACTCTTAACTGAGACAAGATTTCGCCATGTTGCCCAGGCTGGTCTCGAACTTCT
GAGCTCAAGCGATCTACCTGCCTCGTCCTCCCAAAGTGTTGGAATTGCAGGTGTGAGCCACTGCACCCGGCCCTTGCCTCATGTTTGAAT
GATAATTTACCTGGGCATAAAATTCTGGACACTTGTGGTGGCACGAGCTGTCTGCTTTTCTGTGGAGACTGCGGGTTGCAGACACCAGCA
GCCCCCTATTGCTGCACGTCAGGTGTCCTCCACCTCAGTACTGTGGACATCTCGGGCCGCATAGCCCTGTTGCGCGGGCATCCTGTGCGT
TGCAGGAGATGCAGCAGCATCCATGACCGCAACCCATCAGAGTGTTCTAAGAACGGAAGCATCTGGGCTGGATGGAATTTAGCATCAAGC
AGAGTCCCCTTTCTGTTCAGAGTGTTGTAAAGTGCATAAAGATGAAGCAGGCACCAGAAATCCTCGGCAGTGCCAACGGGAAGACTCCGA
GCTGCGAGGTGAACCGCGAGTGTTCTGTGTTCCTCAGCAAAGCCCAGCTCTCCAGTAGCCTGCAGGAGGGGGTCATGCAGAAGTTTAACG
GCCACGACGCCCTGCCCTTTATTCCAGCCGACAAGCTGAAAGATCTTACTTCCCGGGTGTTTAATGGAGAACCCGGCGCACACGATGCCA
AACTGCGTTTTGAGTCCCAGGAAATGAAAGGGATTGGGACACCCCCTAACACTACCCCTATCAAAAATGGCTCTCCAGAAATTAAGCTGA
AAATCACCAAAACATACATGAATGGGAAGCCTCTCTTTGAATCTTCCATTTGTGGTGACAGTGCTGCTGATGTGTCTCAGTCAGAAGAAA
ATGGACAAAAACCAGAAAACAAGGCGAGAAGGAACAGGAAGAGGAGCATAAAATATGACTCCTTGCTGGAGCAGGGCCTTGTCGAAGCAG
CTCTTGTGTCTAAGATCTCAAGTCCTTCAGATAAAAAGATTCCAGCTAAGAAAGAGTCTTGTCCAAACACTGGAAGAGACAAAGACCACC
TGTTGAAATACAACGTTGGTGATTTGGTGTGGTCCAAAGTGTCGGGTTACCCTTGGTGGCCTTGCATGGTTTCTGCAGATCCACTCCTTC
ACAGCTATACCAAACTTAAAGGTCAGAAAAAGAGTGCACGCCAGTATCACGTACAGTTCTTTGGTGACGCCCCAGAAAGAGCTTGGATAT
TTGAGAAGAGCCTCGTAGCTTTTGAAGGAGAAGGACAGTTTGAAAAATTATGCCAGGAAAGTGCCAAGCAGGCACCCACGAAAGCTGAGA
AAATTAAGCTATTGAAACCAATTTCAGGGAAATTGAGGGCCCAGTGGGAAATGGGCATTGTTCAAGCAGAAGAAGCTGCAAGCATGTCAG
TGGAGGAGCGGAAAGCCAAGTTCACCTTTCTCTATGTGGGGGACCAGCTTCATCTCAACCCTCAAGTAGCCAAGGAGGCTGGCATTGCTG
CAGAGTCTTTGGGAGAAATGGCAGAATCCTCAGGAGTCAGTGAAGAAGCTGCTGAAAACCCCAAGTCTGTGAGAGAAGAGTGCATTCCCA
TGAAGAGAAGGCGGAGGGCCAAACTGTGTAGCTCTGCAGAGACCCTGGAGAGTCACCCCGACATAGGGAAGAGTACTCCTCAAAAGACGG
CAGAGGCTGACCCCAGAAGAGGAGTAGGGTCTCCTCCTGGGAGGAAGAAGACCACAGTCTCCATGCCACGAAGCAGGAAGGGAGATGCAG
CATCCCAGTTTTTGGTCTTCTGTCAAAAACACAGGGATGAGGTGGTAGCTGAGCACCCAGATGCTTCAGGTGAGGAGATTGAAGAGCTGC
TCAGGTCACAGTGGAGTCTGCTGAGTGAGAAGCAGAGAGCACGCTACAACACCAAGTTTGCCCTGGTGGCCCCTGTCCAGGCTGAAGAAG
ACTCTGGTAATGTAAATGGGAAAAAAAGAAACCACACAAAGAGGATACAGGACCCTACAGAAGATGCTGAAGCTGAGGACACACCCAGGA
AAAGACTCAGGACGGACAAGCACAGTCTTCGGAAGAGAGACACAATCACTGACAAAACGGCCAGAACAAGCTCTTACAAGGCCATGGAGG
CAGCCTCCTCGCTCAAGAGCCAGGCAGCAACGAAAAATCTGTCTGATGCATGTAAACCACTGAAGAAGCGAAATCGGGCTTCCACGGCAG
CATCTTCAGCTCTTGGGTTTAGCAAAAGTTCATCTCCTTCTGCATCCTTAACTGAGAATGAGGTCTCGGACAGCCCGGGAGACGAGCCCT
CGGAGTCCCCATACGAAAGTGCAGACGAAACACAAACTGAAGTATCTGTCTCATCCAAAAAGTCTGAGCGAGGAGTGACTGCCAAAAAGG
AGTATGTGTGCCAGCTGTGTGAGAAGCCGGGCAGCCTCCTGCTCTGTGAAGGACCCTGCTGCGGAGCTTTCCACCTCGCCTGCCTTGGGC
TTTCCCGGAGGCCAGAAGGGAGGTTCACCTGCAGCGAGTGTGCCTCAGGGATTCACTCATGTTTCGTGTGTAAAGAGAGCAAGACAGATG
TTAAGCGCTGTGTGGTAACTCAGTGTGGAAAATTTTACCATGAGGCTTGTGTGAAAAAATACCCTCTGACTGTATTTGAGAGCCGAGGTT
TCCGCTGCCCCCTCCACAGCTGTGTGAGCTGCCATGCTTCCAACCCTTCAAACCCAAGGCCGTCAAAAGGTAAAATGATGCGGTGTGTCC
GCTGCCCCGTTGCCTATCACAGCGGGGATGCTTGTCTGGCAGCAGGATGCTCAGTGATCGCCTCCAACAGCATCATCTGCACTGCCCACT
TCACTGCTCGGAAGGGGAAGCGACACCACGCCCACGTCAACGTGAGCTGGTGCTTCGTGTGCTCCAAAGGGGGGAGCCTTCTGTGCTGTG
AGTCCTGCCCAGCGGCCTTCCACCCTGACTGCCTGAACATCGAGATGCCTGACGGCAGCTGGTTCTGCAATGACTGCAGGGCTGGGAAGA
AGCTGCACTTCCAGGATATCATTTGGGTGAAACTTGGGAACTACAGATGGTGGCCGGCAGAAGTTTGCCATCCCAAAAATGTTCCCCCAA
ATATTCAGAAAATGAAGCACGAGATTGGAGAATTCCCTGTGTTTTTCTTTGGGTCTAAAGATTATTACTGGACGCATCAGGCGCGAGTGT
TCCCGTACATGGAGGGGGACCGGGGCAGCCGCTACCAGGGGGTCAGAGGGATCGGAAGAGTCTTCAAAAACGGTCAAAAGGCTGAGTTTC
AAATTCTGGATAATGTAGACTCAACGGGAGAGTTGATAGTGAGATTACCCAAAGAAATAACAATTTCAGGCAGTTTCCAGGGCTTCCACC
ATCAGAAAATCAAGATATCGGAGAACCGGATATCCCAGCAGTATCTGGCTACCCTTGAAAACAGGAAGCTGAAGAGGGAACTACCCTTTT
CATTCCGATCAATTAATACGAGAGAAAACCTGTATCTGGTGACAGAAACTCTGGAGACGGTAAAGGAGGAAACCCTGAAAAGCGACCGGC
AATATAAATTTTGGAGCCAGATCTCTCAGGGCCATCTCAGCTATAAACACAAGGGCCAAAGGGAAGTGACCATCCCCCCAAATCGGGTCC
TGAGCTATCGAGTAAAGCAGCTTGTCTTCCCCAACAAGGAGACGATGAGAAAGTCTTTGGGTTCGGAGGATTCCAGAAACATGAAGGAGA
AGTTGGAGGACATGGAGAGTGTCCTCAAGGACCTGACAGAGGAGAAGAGAAAAGATGTGCTAAACTCCCTCGCTAAGTGCCTCGGCAAGG
AGGATATTCGGCAGGATCTAGAGCAAAGAGTATCTGAGGTCCTGATTTCCGGGGAGCTACACATGGAGGACCCAGACAAGCCTCTCCTAA
GCAGCCTTTTTAATGCTGCTGGGGTCTTGGTAGAAGCGCGTGCAAAAGCCATTCTGGACTTCCTGGATGCCCTGCTAGAGCTGTCTGAAG
AGCAGCAGTTTGTGGCTGAGGCCCTGGAGAAGGGGACCCTTCCTCTGTTGAAGGACCAGGTGAAATCTGTCATGGAGCAGAACTGGGATG
AGCTGGCCAGCAGTCCTCCTGACATGGACTATGACCCTGAGGCACGAATTCTCTGTGCGCTGTATGTTGTTGTCTCTATCCTGCTGGAGC
TGGCTGAGGGGCCTACCTCTGTCTCTTCCTAACTACAAAAGCCCTTTCTCCCCACAAGCCTCTGGGTTTTCCCTTTACCAGTCTGTCCTC
ACTGCCATCGCCACTACCATCCTGTCACCAGTGGGACCTCTTTAAAACAAGCAGCCAACCATTCTTTGATGTATCCCATTCGCTCCATGT

>99189_99189_21_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000382895_GSDMB_chr17_38068750_ENST00000394175_length(amino acids)=1279AA_BP=963
MGWMEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEGVMQKFNGHDALPFIPADKLKDLTSRVF
NGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNGSPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDS
LLEQGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFF
GDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNP
QVAKEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGKSTPQKTAEADPRRGVGSPPGRKKTTVS
MPRSRKGDAASQFLVFCQKHRDEVVAEHPDASGEEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTE
DAEAEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKRNRASTAASSALGFSKSSSPSASLTENE
VSDSPGDEPSESPYESADETQTEVSVSSKKSERGVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSC
FVCKESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKGKMMRCVRCPVAYHSGDACLAAGCSVIA
SNSIICTAHFTARKGKRHHAHVNVSWCFVCSKGGSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAE
VCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKNGQKAEFQILDNVDSTGELIVRLPKEIT
ISGSFQGFHHQKIKISENRISQQYLATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWSQISQGHLSYKHKGQR
EVTIPPNRVLSYRVKQLVFPNKETMRKSLGSEDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELH
MEDPDKPLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQNWDELASSPPDMDYDPEARILCAL

--------------------------------------------------------------
>99189_99189_22_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000382895_GSDMB_chr17_38068750_ENST00000394179_length(transcript)=4528nt_BP=3312nt
GCATGAGCCACCGTGCCTGTCCTAGAACCACTGGTAACTCTTAACTGAGACAAGATTTCGCCATGTTGCCCAGGCTGGTCTCGAACTTCT
GAGCTCAAGCGATCTACCTGCCTCGTCCTCCCAAAGTGTTGGAATTGCAGGTGTGAGCCACTGCACCCGGCCCTTGCCTCATGTTTGAAT
GATAATTTACCTGGGCATAAAATTCTGGACACTTGTGGTGGCACGAGCTGTCTGCTTTTCTGTGGAGACTGCGGGTTGCAGACACCAGCA
GCCCCCTATTGCTGCACGTCAGGTGTCCTCCACCTCAGTACTGTGGACATCTCGGGCCGCATAGCCCTGTTGCGCGGGCATCCTGTGCGT
TGCAGGAGATGCAGCAGCATCCATGACCGCAACCCATCAGAGTGTTCTAAGAACGGAAGCATCTGGGCTGGATGGAATTTAGCATCAAGC
AGAGTCCCCTTTCTGTTCAGAGTGTTGTAAAGTGCATAAAGATGAAGCAGGCACCAGAAATCCTCGGCAGTGCCAACGGGAAGACTCCGA
GCTGCGAGGTGAACCGCGAGTGTTCTGTGTTCCTCAGCAAAGCCCAGCTCTCCAGTAGCCTGCAGGAGGGGGTCATGCAGAAGTTTAACG
GCCACGACGCCCTGCCCTTTATTCCAGCCGACAAGCTGAAAGATCTTACTTCCCGGGTGTTTAATGGAGAACCCGGCGCACACGATGCCA
AACTGCGTTTTGAGTCCCAGGAAATGAAAGGGATTGGGACACCCCCTAACACTACCCCTATCAAAAATGGCTCTCCAGAAATTAAGCTGA
AAATCACCAAAACATACATGAATGGGAAGCCTCTCTTTGAATCTTCCATTTGTGGTGACAGTGCTGCTGATGTGTCTCAGTCAGAAGAAA
ATGGACAAAAACCAGAAAACAAGGCGAGAAGGAACAGGAAGAGGAGCATAAAATATGACTCCTTGCTGGAGCAGGGCCTTGTCGAAGCAG
CTCTTGTGTCTAAGATCTCAAGTCCTTCAGATAAAAAGATTCCAGCTAAGAAAGAGTCTTGTCCAAACACTGGAAGAGACAAAGACCACC
TGTTGAAATACAACGTTGGTGATTTGGTGTGGTCCAAAGTGTCGGGTTACCCTTGGTGGCCTTGCATGGTTTCTGCAGATCCACTCCTTC
ACAGCTATACCAAACTTAAAGGTCAGAAAAAGAGTGCACGCCAGTATCACGTACAGTTCTTTGGTGACGCCCCAGAAAGAGCTTGGATAT
TTGAGAAGAGCCTCGTAGCTTTTGAAGGAGAAGGACAGTTTGAAAAATTATGCCAGGAAAGTGCCAAGCAGGCACCCACGAAAGCTGAGA
AAATTAAGCTATTGAAACCAATTTCAGGGAAATTGAGGGCCCAGTGGGAAATGGGCATTGTTCAAGCAGAAGAAGCTGCAAGCATGTCAG
TGGAGGAGCGGAAAGCCAAGTTCACCTTTCTCTATGTGGGGGACCAGCTTCATCTCAACCCTCAAGTAGCCAAGGAGGCTGGCATTGCTG
CAGAGTCTTTGGGAGAAATGGCAGAATCCTCAGGAGTCAGTGAAGAAGCTGCTGAAAACCCCAAGTCTGTGAGAGAAGAGTGCATTCCCA
TGAAGAGAAGGCGGAGGGCCAAACTGTGTAGCTCTGCAGAGACCCTGGAGAGTCACCCCGACATAGGGAAGAGTACTCCTCAAAAGACGG
CAGAGGCTGACCCCAGAAGAGGAGTAGGGTCTCCTCCTGGGAGGAAGAAGACCACAGTCTCCATGCCACGAAGCAGGAAGGGAGATGCAG
CATCCCAGTTTTTGGTCTTCTGTCAAAAACACAGGGATGAGGTGGTAGCTGAGCACCCAGATGCTTCAGGTGAGGAGATTGAAGAGCTGC
TCAGGTCACAGTGGAGTCTGCTGAGTGAGAAGCAGAGAGCACGCTACAACACCAAGTTTGCCCTGGTGGCCCCTGTCCAGGCTGAAGAAG
ACTCTGGTAATGTAAATGGGAAAAAAAGAAACCACACAAAGAGGATACAGGACCCTACAGAAGATGCTGAAGCTGAGGACACACCCAGGA
AAAGACTCAGGACGGACAAGCACAGTCTTCGGAAGAGAGACACAATCACTGACAAAACGGCCAGAACAAGCTCTTACAAGGCCATGGAGG
CAGCCTCCTCGCTCAAGAGCCAGGCAGCAACGAAAAATCTGTCTGATGCATGTAAACCACTGAAGAAGCGAAATCGGGCTTCCACGGCAG
CATCTTCAGCTCTTGGGTTTAGCAAAAGTTCATCTCCTTCTGCATCCTTAACTGAGAATGAGGTCTCGGACAGCCCGGGAGACGAGCCCT
CGGAGTCCCCATACGAAAGTGCAGACGAAACACAAACTGAAGTATCTGTCTCATCCAAAAAGTCTGAGCGAGGAGTGACTGCCAAAAAGG
AGTATGTGTGCCAGCTGTGTGAGAAGCCGGGCAGCCTCCTGCTCTGTGAAGGACCCTGCTGCGGAGCTTTCCACCTCGCCTGCCTTGGGC
TTTCCCGGAGGCCAGAAGGGAGGTTCACCTGCAGCGAGTGTGCCTCAGGGATTCACTCATGTTTCGTGTGTAAAGAGAGCAAGACAGATG
TTAAGCGCTGTGTGGTAACTCAGTGTGGAAAATTTTACCATGAGGCTTGTGTGAAAAAATACCCTCTGACTGTATTTGAGAGCCGAGGTT
TCCGCTGCCCCCTCCACAGCTGTGTGAGCTGCCATGCTTCCAACCCTTCAAACCCAAGGCCGTCAAAAGGTAAAATGATGCGGTGTGTCC
GCTGCCCCGTTGCCTATCACAGCGGGGATGCTTGTCTGGCAGCAGGATGCTCAGTGATCGCCTCCAACAGCATCATCTGCACTGCCCACT
TCACTGCTCGGAAGGGGAAGCGACACCACGCCCACGTCAACGTGAGCTGGTGCTTCGTGTGCTCCAAAGGGGGGAGCCTTCTGTGCTGTG
AGTCCTGCCCAGCGGCCTTCCACCCTGACTGCCTGAACATCGAGATGCCTGACGGCAGCTGGTTCTGCAATGACTGCAGGGCTGGGAAGA
AGCTGCACTTCCAGGATATCATTTGGGTGAAACTTGGGAACTACAGATGGTGGCCGGCAGAAGTTTGCCATCCCAAAAATGTTCCCCCAA
ATATTCAGAAAATGAAGCACGAGATTGGAGAATTCCCTGTGTTTTTCTTTGGGTCTAAAGATTATTACTGGACGCATCAGGCGCGAGTGT
TCCCGTACATGGAGGGGGACCGGGGCAGCCGCTACCAGGGGGTCAGAGGGATCGGAAGAGTCTTCAAAAACGGTCAAAAGGCTGAGTTTC
AAATTCTGGATAATGTAGACTCAACGGGAGAGTTGATAGTGAGATTACCCAAAGAAATAACAATTTCAGGCAGTTTCCAGGGCTTCCACC
ATCAGAAAATCAAGATATCGGAGAACCGGATATCCCAGCAGTATCTGGCTACCCTTGAAAACAGGAAGCTGAAGAGGGAACTACCCTTTT
CATTCCGATCAATTAATACGAGAGAAAACCTGTATCTGGTGACAGAAACTCTGGAGACGGTAAAGGAGGAAACCCTGAAAAGCGACCGGC
AATATAAATTTTGGAGCCAGATCTCTCAGGGCCATCTCAGCTATAAACACAAGGGCCAAAGGGAAGTGACCATCCCCCCAAATCGGGTCC
TGAGCTATCGAGTAAAGCAGCTTGTCTTCCCCAACAAGGAGACGATGAGTGCTGGTTTAGATATTCATTTCAGGGGCAAAACAAAATCCT
TTCCAGAAGGAAAGTCTTTGGGTTCGGAGGATTCCAGAAACATGAAGGAGAAGTTGGAGGACATGGAGAGTGTCCTCAAGGACCTGACAG
AGGAGAAGAGAAAAGATGTGCTAAACTCCCTCGCTAAGTGCCTCGGCAAGGAGGATATTCGGCAGGATCTAGAGCAAAGAGTATCTGAGG
TCCTGATTTCCGGGGAGCTACACATGGAGGACCCAGACAAGCCTCTCCTAAGCAGCCTTTTTAATGCTGCTGGGGTCTTGGTAGAAGCGC
GTGCAAAAGCCATTCTGGACTTCCTGGATGCCCTGCTAGAGCTGTCTGAAGAGCAGCAGTTTGTGGCTGAGGCCCTGGAGAAGGGGACCC
TTCCTCTGTTGAAGGACCAGGTGAAATCTGTCATGGAGCAGAACTGGGATGAGCTGGCCAGCAGTCCTCCTGACATGGACTATGACCCTG
AGGCACGAATTCTCTGTGCGCTGTATGTTGTTGTCTCTATCCTGCTGGAGCTGGCTGAGGGGCCTACCTCTGTCTCTTCCTAACTACAAA
AGCCCTTTCTCCCCACAAGCCTCTGGGTTTTCCCTTTACCAGTCTGTCCTCACTGCCATCGCCACTACCATCCTGTCACCAGTGGGACCT
CTTTAAAACAAGCAGCCAACCATTCTTTGATGTATCCCATTCGCTCCATGTTAACATCCAAAACCAGCCTGGATTTCATACATGGACTTC

>99189_99189_22_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000382895_GSDMB_chr17_38068750_ENST00000394179_length(amino acids)=1296AA_BP=963
MGWMEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEGVMQKFNGHDALPFIPADKLKDLTSRVF
NGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNGSPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDS
LLEQGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFF
GDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNP
QVAKEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGKSTPQKTAEADPRRGVGSPPGRKKTTVS
MPRSRKGDAASQFLVFCQKHRDEVVAEHPDASGEEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTE
DAEAEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKRNRASTAASSALGFSKSSSPSASLTENE
VSDSPGDEPSESPYESADETQTEVSVSSKKSERGVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSC
FVCKESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKGKMMRCVRCPVAYHSGDACLAAGCSVIA
SNSIICTAHFTARKGKRHHAHVNVSWCFVCSKGGSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAE
VCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKNGQKAEFQILDNVDSTGELIVRLPKEIT
ISGSFQGFHHQKIKISENRISQQYLATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWSQISQGHLSYKHKGQR
EVTIPPNRVLSYRVKQLVFPNKETMSAGLDIHFRGKTKSFPEGKSLGSEDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIR
QDLEQRVSEVLISGELHMEDPDKPLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQNWDELAS

--------------------------------------------------------------
>99189_99189_23_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000382895_GSDMB_chr17_38068750_ENST00000418519_length(transcript)=4543nt_BP=3312nt
GCATGAGCCACCGTGCCTGTCCTAGAACCACTGGTAACTCTTAACTGAGACAAGATTTCGCCATGTTGCCCAGGCTGGTCTCGAACTTCT
GAGCTCAAGCGATCTACCTGCCTCGTCCTCCCAAAGTGTTGGAATTGCAGGTGTGAGCCACTGCACCCGGCCCTTGCCTCATGTTTGAAT
GATAATTTACCTGGGCATAAAATTCTGGACACTTGTGGTGGCACGAGCTGTCTGCTTTTCTGTGGAGACTGCGGGTTGCAGACACCAGCA
GCCCCCTATTGCTGCACGTCAGGTGTCCTCCACCTCAGTACTGTGGACATCTCGGGCCGCATAGCCCTGTTGCGCGGGCATCCTGTGCGT
TGCAGGAGATGCAGCAGCATCCATGACCGCAACCCATCAGAGTGTTCTAAGAACGGAAGCATCTGGGCTGGATGGAATTTAGCATCAAGC
AGAGTCCCCTTTCTGTTCAGAGTGTTGTAAAGTGCATAAAGATGAAGCAGGCACCAGAAATCCTCGGCAGTGCCAACGGGAAGACTCCGA
GCTGCGAGGTGAACCGCGAGTGTTCTGTGTTCCTCAGCAAAGCCCAGCTCTCCAGTAGCCTGCAGGAGGGGGTCATGCAGAAGTTTAACG
GCCACGACGCCCTGCCCTTTATTCCAGCCGACAAGCTGAAAGATCTTACTTCCCGGGTGTTTAATGGAGAACCCGGCGCACACGATGCCA
AACTGCGTTTTGAGTCCCAGGAAATGAAAGGGATTGGGACACCCCCTAACACTACCCCTATCAAAAATGGCTCTCCAGAAATTAAGCTGA
AAATCACCAAAACATACATGAATGGGAAGCCTCTCTTTGAATCTTCCATTTGTGGTGACAGTGCTGCTGATGTGTCTCAGTCAGAAGAAA
ATGGACAAAAACCAGAAAACAAGGCGAGAAGGAACAGGAAGAGGAGCATAAAATATGACTCCTTGCTGGAGCAGGGCCTTGTCGAAGCAG
CTCTTGTGTCTAAGATCTCAAGTCCTTCAGATAAAAAGATTCCAGCTAAGAAAGAGTCTTGTCCAAACACTGGAAGAGACAAAGACCACC
TGTTGAAATACAACGTTGGTGATTTGGTGTGGTCCAAAGTGTCGGGTTACCCTTGGTGGCCTTGCATGGTTTCTGCAGATCCACTCCTTC
ACAGCTATACCAAACTTAAAGGTCAGAAAAAGAGTGCACGCCAGTATCACGTACAGTTCTTTGGTGACGCCCCAGAAAGAGCTTGGATAT
TTGAGAAGAGCCTCGTAGCTTTTGAAGGAGAAGGACAGTTTGAAAAATTATGCCAGGAAAGTGCCAAGCAGGCACCCACGAAAGCTGAGA
AAATTAAGCTATTGAAACCAATTTCAGGGAAATTGAGGGCCCAGTGGGAAATGGGCATTGTTCAAGCAGAAGAAGCTGCAAGCATGTCAG
TGGAGGAGCGGAAAGCCAAGTTCACCTTTCTCTATGTGGGGGACCAGCTTCATCTCAACCCTCAAGTAGCCAAGGAGGCTGGCATTGCTG
CAGAGTCTTTGGGAGAAATGGCAGAATCCTCAGGAGTCAGTGAAGAAGCTGCTGAAAACCCCAAGTCTGTGAGAGAAGAGTGCATTCCCA
TGAAGAGAAGGCGGAGGGCCAAACTGTGTAGCTCTGCAGAGACCCTGGAGAGTCACCCCGACATAGGGAAGAGTACTCCTCAAAAGACGG
CAGAGGCTGACCCCAGAAGAGGAGTAGGGTCTCCTCCTGGGAGGAAGAAGACCACAGTCTCCATGCCACGAAGCAGGAAGGGAGATGCAG
CATCCCAGTTTTTGGTCTTCTGTCAAAAACACAGGGATGAGGTGGTAGCTGAGCACCCAGATGCTTCAGGTGAGGAGATTGAAGAGCTGC
TCAGGTCACAGTGGAGTCTGCTGAGTGAGAAGCAGAGAGCACGCTACAACACCAAGTTTGCCCTGGTGGCCCCTGTCCAGGCTGAAGAAG
ACTCTGGTAATGTAAATGGGAAAAAAAGAAACCACACAAAGAGGATACAGGACCCTACAGAAGATGCTGAAGCTGAGGACACACCCAGGA
AAAGACTCAGGACGGACAAGCACAGTCTTCGGAAGAGAGACACAATCACTGACAAAACGGCCAGAACAAGCTCTTACAAGGCCATGGAGG
CAGCCTCCTCGCTCAAGAGCCAGGCAGCAACGAAAAATCTGTCTGATGCATGTAAACCACTGAAGAAGCGAAATCGGGCTTCCACGGCAG
CATCTTCAGCTCTTGGGTTTAGCAAAAGTTCATCTCCTTCTGCATCCTTAACTGAGAATGAGGTCTCGGACAGCCCGGGAGACGAGCCCT
CGGAGTCCCCATACGAAAGTGCAGACGAAACACAAACTGAAGTATCTGTCTCATCCAAAAAGTCTGAGCGAGGAGTGACTGCCAAAAAGG
AGTATGTGTGCCAGCTGTGTGAGAAGCCGGGCAGCCTCCTGCTCTGTGAAGGACCCTGCTGCGGAGCTTTCCACCTCGCCTGCCTTGGGC
TTTCCCGGAGGCCAGAAGGGAGGTTCACCTGCAGCGAGTGTGCCTCAGGGATTCACTCATGTTTCGTGTGTAAAGAGAGCAAGACAGATG
TTAAGCGCTGTGTGGTAACTCAGTGTGGAAAATTTTACCATGAGGCTTGTGTGAAAAAATACCCTCTGACTGTATTTGAGAGCCGAGGTT
TCCGCTGCCCCCTCCACAGCTGTGTGAGCTGCCATGCTTCCAACCCTTCAAACCCAAGGCCGTCAAAAGGTAAAATGATGCGGTGTGTCC
GCTGCCCCGTTGCCTATCACAGCGGGGATGCTTGTCTGGCAGCAGGATGCTCAGTGATCGCCTCCAACAGCATCATCTGCACTGCCCACT
TCACTGCTCGGAAGGGGAAGCGACACCACGCCCACGTCAACGTGAGCTGGTGCTTCGTGTGCTCCAAAGGGGGGAGCCTTCTGTGCTGTG
AGTCCTGCCCAGCGGCCTTCCACCCTGACTGCCTGAACATCGAGATGCCTGACGGCAGCTGGTTCTGCAATGACTGCAGGGCTGGGAAGA
AGCTGCACTTCCAGGATATCATTTGGGTGAAACTTGGGAACTACAGATGGTGGCCGGCAGAAGTTTGCCATCCCAAAAATGTTCCCCCAA
ATATTCAGAAAATGAAGCACGAGATTGGAGAATTCCCTGTGTTTTTCTTTGGGTCTAAAGATTATTACTGGACGCATCAGGCGCGAGTGT
TCCCGTACATGGAGGGGGACCGGGGCAGCCGCTACCAGGGGGTCAGAGGGATCGGAAGAGTCTTCAAAAACGGTCAAAAGGCTGAGTTTC
AAATTCTGGATAATGTAGACTCAACGGGAGAGTTGATAGTGAGATTACCCAAAGAAATAACAATTTCAGGCAGTTTCCAGGGCTTCCACC
ATCAGAAAATCAAGATATCGGAGAACCGGATATCCCAGCAGTATCTGGCTACCCTTGAAAACAGGAAGCTGAAGAGGGAACTACCCTTTT
CATTCCGATCAATTAATACGAGAGAAAACCTGTATCTGGTGACAGAAACTCTGGAGACGGTAAAGGAGGAAACCCTGAAAAGCGACCGGC
AATATAAATTTTGGAGCCAGATCTCTCAGGGCCATCTCAGCTATAAACACAAGGGCCAAAGGGAAGTGACCATCCCCCCAAATCGGGTCC
TGAGCTATCGAGTAAAGCAGCTTGTCTTCCCCAACAAGGAGACGATGAATATTCATTTCAGGGGCAAAACAAAATCCTTTCCAGAAGAGA
AGGATGGTGCTTCATCCTGTTTAGGAAAGTCTTTGGGTTCGGAGGATTCCAGAAACATGAAGGAGAAGTTGGAGGACATGGAGAGTGTCC
TCAAGGACCTGACAGAGGAGAAGAGAAAAGATGTGCTAAACTCCCTCGCTAAGTGCCTCGGCAAGGAGGATATTCGGCAGGATCTAGAGC
AAAGAGTATCTGAGGTCCTGATTTCCGGGGAGCTACACATGGAGGACCCAGACAAGCCTCTCCTAAGCAGCCTTTTTAATGCTGCTGGGG
TCTTGGTAGAAGCGCGTGCAAAAGCCATTCTGGACTTCCTGGATGCCCTGCTAGAGCTGTCTGAAGAGCAGCAGTTTGTGGCTGAGGCCC
TGGAGAAGGGGACCCTTCCTCTGTTGAAGGACCAGGTGAAATCTGTCATGGAGCAGAACTGGGATGAGCTGGCCAGCAGTCCTCCTGACA
TGGACTATGACCCTGAGGCACGAATTCTCTGTGCGCTGTATGTTGTTGTCTCTATCCTGCTGGAGCTGGCTGAGGGGCCTACCTCTGTCT
CTTCCTAACTACAAAAGCCCTTTCTCCCCACAAGCCTCTGGGTTTTCCCTTTACCAGTCTGTCCTCACTGCCATCGCCACTACCATCCTG
TCACCAGTGGGACCTCTTTAAAACAAGCAGCCAACCATTCTTTGATGTATCCCATTCGCTCCATGTTAACATCCAAAACCAGCCTGGATT

>99189_99189_23_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000382895_GSDMB_chr17_38068750_ENST00000418519_length(amino acids)=1301AA_BP=963
MGWMEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEGVMQKFNGHDALPFIPADKLKDLTSRVF
NGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNGSPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDS
LLEQGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFF
GDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNP
QVAKEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGKSTPQKTAEADPRRGVGSPPGRKKTTVS
MPRSRKGDAASQFLVFCQKHRDEVVAEHPDASGEEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTE
DAEAEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKRNRASTAASSALGFSKSSSPSASLTENE
VSDSPGDEPSESPYESADETQTEVSVSSKKSERGVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSC
FVCKESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKGKMMRCVRCPVAYHSGDACLAAGCSVIA
SNSIICTAHFTARKGKRHHAHVNVSWCFVCSKGGSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAE
VCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKNGQKAEFQILDNVDSTGELIVRLPKEIT
ISGSFQGFHHQKIKISENRISQQYLATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWSQISQGHLSYKHKGQR
EVTIPPNRVLSYRVKQLVFPNKETMNIHFRGKTKSFPEEKDGASSCLGKSLGSEDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLG
KEDIRQDLEQRVSEVLISGELHMEDPDKPLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQNW

--------------------------------------------------------------
>99189_99189_24_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000382895_GSDMB_chr17_38068750_ENST00000520542_length(transcript)=4516nt_BP=3312nt
GCATGAGCCACCGTGCCTGTCCTAGAACCACTGGTAACTCTTAACTGAGACAAGATTTCGCCATGTTGCCCAGGCTGGTCTCGAACTTCT
GAGCTCAAGCGATCTACCTGCCTCGTCCTCCCAAAGTGTTGGAATTGCAGGTGTGAGCCACTGCACCCGGCCCTTGCCTCATGTTTGAAT
GATAATTTACCTGGGCATAAAATTCTGGACACTTGTGGTGGCACGAGCTGTCTGCTTTTCTGTGGAGACTGCGGGTTGCAGACACCAGCA
GCCCCCTATTGCTGCACGTCAGGTGTCCTCCACCTCAGTACTGTGGACATCTCGGGCCGCATAGCCCTGTTGCGCGGGCATCCTGTGCGT
TGCAGGAGATGCAGCAGCATCCATGACCGCAACCCATCAGAGTGTTCTAAGAACGGAAGCATCTGGGCTGGATGGAATTTAGCATCAAGC
AGAGTCCCCTTTCTGTTCAGAGTGTTGTAAAGTGCATAAAGATGAAGCAGGCACCAGAAATCCTCGGCAGTGCCAACGGGAAGACTCCGA
GCTGCGAGGTGAACCGCGAGTGTTCTGTGTTCCTCAGCAAAGCCCAGCTCTCCAGTAGCCTGCAGGAGGGGGTCATGCAGAAGTTTAACG
GCCACGACGCCCTGCCCTTTATTCCAGCCGACAAGCTGAAAGATCTTACTTCCCGGGTGTTTAATGGAGAACCCGGCGCACACGATGCCA
AACTGCGTTTTGAGTCCCAGGAAATGAAAGGGATTGGGACACCCCCTAACACTACCCCTATCAAAAATGGCTCTCCAGAAATTAAGCTGA
AAATCACCAAAACATACATGAATGGGAAGCCTCTCTTTGAATCTTCCATTTGTGGTGACAGTGCTGCTGATGTGTCTCAGTCAGAAGAAA
ATGGACAAAAACCAGAAAACAAGGCGAGAAGGAACAGGAAGAGGAGCATAAAATATGACTCCTTGCTGGAGCAGGGCCTTGTCGAAGCAG
CTCTTGTGTCTAAGATCTCAAGTCCTTCAGATAAAAAGATTCCAGCTAAGAAAGAGTCTTGTCCAAACACTGGAAGAGACAAAGACCACC
TGTTGAAATACAACGTTGGTGATTTGGTGTGGTCCAAAGTGTCGGGTTACCCTTGGTGGCCTTGCATGGTTTCTGCAGATCCACTCCTTC
ACAGCTATACCAAACTTAAAGGTCAGAAAAAGAGTGCACGCCAGTATCACGTACAGTTCTTTGGTGACGCCCCAGAAAGAGCTTGGATAT
TTGAGAAGAGCCTCGTAGCTTTTGAAGGAGAAGGACAGTTTGAAAAATTATGCCAGGAAAGTGCCAAGCAGGCACCCACGAAAGCTGAGA
AAATTAAGCTATTGAAACCAATTTCAGGGAAATTGAGGGCCCAGTGGGAAATGGGCATTGTTCAAGCAGAAGAAGCTGCAAGCATGTCAG
TGGAGGAGCGGAAAGCCAAGTTCACCTTTCTCTATGTGGGGGACCAGCTTCATCTCAACCCTCAAGTAGCCAAGGAGGCTGGCATTGCTG
CAGAGTCTTTGGGAGAAATGGCAGAATCCTCAGGAGTCAGTGAAGAAGCTGCTGAAAACCCCAAGTCTGTGAGAGAAGAGTGCATTCCCA
TGAAGAGAAGGCGGAGGGCCAAACTGTGTAGCTCTGCAGAGACCCTGGAGAGTCACCCCGACATAGGGAAGAGTACTCCTCAAAAGACGG
CAGAGGCTGACCCCAGAAGAGGAGTAGGGTCTCCTCCTGGGAGGAAGAAGACCACAGTCTCCATGCCACGAAGCAGGAAGGGAGATGCAG
CATCCCAGTTTTTGGTCTTCTGTCAAAAACACAGGGATGAGGTGGTAGCTGAGCACCCAGATGCTTCAGGTGAGGAGATTGAAGAGCTGC
TCAGGTCACAGTGGAGTCTGCTGAGTGAGAAGCAGAGAGCACGCTACAACACCAAGTTTGCCCTGGTGGCCCCTGTCCAGGCTGAAGAAG
ACTCTGGTAATGTAAATGGGAAAAAAAGAAACCACACAAAGAGGATACAGGACCCTACAGAAGATGCTGAAGCTGAGGACACACCCAGGA
AAAGACTCAGGACGGACAAGCACAGTCTTCGGAAGAGAGACACAATCACTGACAAAACGGCCAGAACAAGCTCTTACAAGGCCATGGAGG
CAGCCTCCTCGCTCAAGAGCCAGGCAGCAACGAAAAATCTGTCTGATGCATGTAAACCACTGAAGAAGCGAAATCGGGCTTCCACGGCAG
CATCTTCAGCTCTTGGGTTTAGCAAAAGTTCATCTCCTTCTGCATCCTTAACTGAGAATGAGGTCTCGGACAGCCCGGGAGACGAGCCCT
CGGAGTCCCCATACGAAAGTGCAGACGAAACACAAACTGAAGTATCTGTCTCATCCAAAAAGTCTGAGCGAGGAGTGACTGCCAAAAAGG
AGTATGTGTGCCAGCTGTGTGAGAAGCCGGGCAGCCTCCTGCTCTGTGAAGGACCCTGCTGCGGAGCTTTCCACCTCGCCTGCCTTGGGC
TTTCCCGGAGGCCAGAAGGGAGGTTCACCTGCAGCGAGTGTGCCTCAGGGATTCACTCATGTTTCGTGTGTAAAGAGAGCAAGACAGATG
TTAAGCGCTGTGTGGTAACTCAGTGTGGAAAATTTTACCATGAGGCTTGTGTGAAAAAATACCCTCTGACTGTATTTGAGAGCCGAGGTT
TCCGCTGCCCCCTCCACAGCTGTGTGAGCTGCCATGCTTCCAACCCTTCAAACCCAAGGCCGTCAAAAGGTAAAATGATGCGGTGTGTCC
GCTGCCCCGTTGCCTATCACAGCGGGGATGCTTGTCTGGCAGCAGGATGCTCAGTGATCGCCTCCAACAGCATCATCTGCACTGCCCACT
TCACTGCTCGGAAGGGGAAGCGACACCACGCCCACGTCAACGTGAGCTGGTGCTTCGTGTGCTCCAAAGGGGGGAGCCTTCTGTGCTGTG
AGTCCTGCCCAGCGGCCTTCCACCCTGACTGCCTGAACATCGAGATGCCTGACGGCAGCTGGTTCTGCAATGACTGCAGGGCTGGGAAGA
AGCTGCACTTCCAGGATATCATTTGGGTGAAACTTGGGAACTACAGATGGTGGCCGGCAGAAGTTTGCCATCCCAAAAATGTTCCCCCAA
ATATTCAGAAAATGAAGCACGAGATTGGAGAATTCCCTGTGTTTTTCTTTGGGTCTAAAGATTATTACTGGACGCATCAGGCGCGAGTGT
TCCCGTACATGGAGGGGGACCGGGGCAGCCGCTACCAGGGGGTCAGAGGGATCGGAAGAGTCTTCAAAAACGGTCAAAAGGCTGAGTTTC
AAATTCTGGATAATGTAGACTCAACGGGAGAGTTGATAGTGAGATTACCCAAAGAAATAACAATTTCAGGCAGTTTCCAGGGCTTCCACC
ATCAGAAAATCAAGATATCGGAGAACCGGATATCCCAGCAGTATCTGGCTACCCTTGAAAACAGGAAGCTGAAGAGGGAACTACCCTTTT
CATTCCGATCAATTAATACGAGAGAAAACCTGTATCTGGTGACAGAAACTCTGGAGACGGTAAAGGAGGAAACCCTGAAAAGCGACCGGC
AATATAAATTTTGGAGCCAGATCTCTCAGGGCCATCTCAGCTATAAACACAAGGGCCAAAGGGAAGTGACCATCCCCCCAAATCGGGTCC
TGAGCTATCGAGTAAAGCAGCTTGTCTTCCCCAACAAGGAGACGATGAATATTCATTTCAGGGGCAAAACAAAATCCTTTCCAGAAGGAA
AGTCTTTGGGTTCGGAGGATTCCAGAAACATGAAGGAGAAGTTGGAGGACATGGAGAGTGTCCTCAAGGACCTGACAGAGGAGAAGAGAA
AAGATGTGCTAAACTCCCTCGCTAAGTGCCTCGGCAAGGAGGATATTCGGCAGGATCTAGAGCAAAGAGTATCTGAGGTCCTGATTTCCG
GGGAGCTACACATGGAGGACCCAGACAAGCCTCTCCTAAGCAGCCTTTTTAATGCTGCTGGGGTCTTGGTAGAAGCGCGTGCAAAAGCCA
TTCTGGACTTCCTGGATGCCCTGCTAGAGCTGTCTGAAGAGCAGCAGTTTGTGGCTGAGGCCCTGGAGAAGGGGACCCTTCCTCTGTTGA
AGGACCAGGTGAAATCTGTCATGGAGCAGAACTGGGATGAGCTGGCCAGCAGTCCTCCTGACATGGACTATGACCCTGAGGCACGAATTC
TCTGTGCGCTGTATGTTGTTGTCTCTATCCTGCTGGAGCTGGCTGAGGGGCCTACCTCTGTCTCTTCCTAACTACAAAAGCCCTTTCTCC
CCACAAGCCTCTGGGTTTTCCCTTTACCAGTCTGTCCTCACTGCCATCGCCACTACCATCCTGTCACCAGTGGGACCTCTTTAAAACAAG
CAGCCAACCATTCTTTGATGTATCCCATTCGCTCCATGTTAACATCCAAAACCAGCCTGGATTTCATACATGGACTTCTGATTAAAAGTG

>99189_99189_24_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000382895_GSDMB_chr17_38068750_ENST00000520542_length(amino acids)=1292AA_BP=963
MGWMEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEGVMQKFNGHDALPFIPADKLKDLTSRVF
NGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNGSPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDS
LLEQGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFF
GDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNP
QVAKEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGKSTPQKTAEADPRRGVGSPPGRKKTTVS
MPRSRKGDAASQFLVFCQKHRDEVVAEHPDASGEEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTE
DAEAEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKRNRASTAASSALGFSKSSSPSASLTENE
VSDSPGDEPSESPYESADETQTEVSVSSKKSERGVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSC
FVCKESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKGKMMRCVRCPVAYHSGDACLAAGCSVIA
SNSIICTAHFTARKGKRHHAHVNVSWCFVCSKGGSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAE
VCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKNGQKAEFQILDNVDSTGELIVRLPKEIT
ISGSFQGFHHQKIKISENRISQQYLATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWSQISQGHLSYKHKGQR
EVTIPPNRVLSYRVKQLVFPNKETMNIHFRGKTKSFPEGKSLGSEDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLE
QRVSEVLISGELHMEDPDKPLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQNWDELASSPPD

--------------------------------------------------------------
>99189_99189_25_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000508803_GSDMB_chr17_38068750_ENST00000309481_length(transcript)=4223nt_BP=3029nt
CGCTGCGCCCGCCGCCGCCGCCGCCCCCTCCCCGCCTGGGCCCTACCGCCGCACGGCCCCGGCCCCCTCCCAGCCTGCCGCTCCGGAGAG
CCGCCCGCCGAGGATGCGACGCACCGCAGTGTTCTAAGAACGGAAGCATCTGGGCTGGATGGAATTTAGCATCAAGCAGAGTCCCCTTTC
TGTTCAGAGTGTTGTAAAGTGCATAAAGATGAAGCAGGCACCAGAAATCCTCGGCAGTGCCAACGGGAAGACTCCGAGCTGCGAGGTGAA
CCGCGAGTGTTCTGTGTTCCTCAGCAAAGCCCAGCTCTCCAGTAGCCTGCAGGAGGGGGTCATGCAGAAGTTTAACGGCCACGACGCCCT
GCCCTTTATTCCAGCCGACAAGCTGAAAGATCTTACTTCCCGGGTGTTTAATGGAGAACCCGGCGCACACGATGCCAAACTGCGTTTTGA
GTCCCAGGAAATGAAAGGGATTGGGACACCCCCTAACACTACCCCTATCAAAAATGGCTCTCCAGAAATTAAGCTGAAAATCACCAAAAC
ATACATGAATGGGAAGCCTCTCTTTGAATCTTCCATTTGTGGTGACAGTGCTGCTGATGTGTCTCAGTCAGAAGAAAATGGACAAAAACC
AGAAAACAAGGCGAGAAGGAACAGGAAGAGGAGCATAAAATATGACTCCTTGCTGGAGCAGGGCCTTGTCGAAGCAGCTCTTGTGTCTAA
GATCTCAAGTCCTTCAGATAAAAAGATTCCAGCTAAGAAAGAGTCTTGTCCAAACACTGGAAGAGACAAAGACCACCTGTTGAAATACAA
CGTTGGTGATTTGGTGTGGTCCAAAGTGTCGGGTTACCCTTGGTGGCCTTGCATGGTTTCTGCAGATCCACTCCTTCACAGCTATACCAA
ACTTAAAGGTCAGAAAAAGAGTGCACGCCAGTATCACGTACAGTTCTTTGGTGACGCCCCAGAAAGAGCTTGGATATTTGAGAAGAGCCT
CGTAGCTTTTGAAGGAGAAGGACAGTTTGAAAAATTATGCCAGGAAAGTGCCAAGCAGGCACCCACGAAAGCTGAGAAAATTAAGCTATT
GAAACCAATTTCAGGGAAATTGAGGGCCCAGTGGGAAATGGGCATTGTTCAAGCAGAAGAAGCTGCAAGCATGTCAGTGGAGGAGCGGAA
AGCCAAGTTCACCTTTCTCTATGTGGGGGACCAGCTTCATCTCAACCCTCAAGTAGCCAAGGAGGCTGGCATTGCTGCAGAGTCTTTGGG
AGAAATGGCAGAATCCTCAGGAGTCAGTGAAGAAGCTGCTGAAAACCCCAAGTCTGTGAGAGAAGAGTGCATTCCCATGAAGAGAAGGCG
GAGGGCCAAACTGTGTAGCTCTGCAGAGACCCTGGAGAGTCACCCCGACATAGGGAAGAGTACTCCTCAAAAGACGGCAGAGGCTGACCC
CAGAAGAGGAGTAGGGTCTCCTCCTGGGAGGAAGAAGACCACAGTCTCCATGCCACGAAGCAGGAAGGGAGATGCAGCATCCCAGTTTTT
GGTCTTCTGTCAAAAACACAGGGATGAGGTGGTAGCTGAGCACCCAGATGCTTCAGGTGAGGAGATTGAAGAGCTGCTCAGGTCACAGTG
GAGTCTGCTGAGTGAGAAGCAGAGAGCACGCTACAACACCAAGTTTGCCCTGGTGGCCCCTGTCCAGGCTGAAGAAGACTCTGGTAATGT
AAATGGGAAAAAAAGAAACCACACAAAGAGGATACAGGACCCTACAGAAGATGCTGAAGCTGAGGACACACCCAGGAAAAGACTCAGGAC
GGACAAGCACAGTCTTCGGAAGAGAGACACAATCACTGACAAAACGGCCAGAACAAGCTCTTACAAGGCCATGGAGGCAGCCTCCTCGCT
CAAGAGCCAGGCAGCAACGAAAAATCTGTCTGATGCATGTAAACCACTGAAGAAGCGAAATCGGGCTTCCACGGCAGCATCTTCAGCTCT
TGGGTTTAGCAAAAGTTCATCTCCTTCTGCATCCTTAACTGAGAATGAGGTCTCGGACAGCCCGGGAGACGAGCCCTCGGAGTCCCCATA
CGAAAGTGCAGACGAAACACAAACTGAAGTATCTGTCTCATCCAAAAAGTCTGAGCGAGGAGTGACTGCCAAAAAGGAGTATGTGTGCCA
GCTGTGTGAGAAGCCGGGCAGCCTCCTGCTCTGTGAAGGACCCTGCTGCGGAGCTTTCCACCTCGCCTGCCTTGGGCTTTCCCGGAGGCC
AGAAGGGAGGTTCACCTGCAGCGAGTGTGCCTCAGGGATTCACTCATGTTTCGTGTGTAAAGAGAGCAAGACAGATGTTAAGCGCTGTGT
GGTAACTCAGTGTGGAAAATTTTACCATGAGGCTTGTGTGAAAAAATACCCTCTGACTGTATTTGAGAGCCGAGGTTTCCGCTGCCCCCT
CCACAGCTGTGTGAGCTGCCATGCTTCCAACCCTTCAAACCCAAGGCCGTCAAAAGGTAAAATGATGCGGTGTGTCCGCTGCCCCGTTGC
CTATCACAGCGGGGATGCTTGTCTGGCAGCAGGATGCTCAGTGATCGCCTCCAACAGCATCATCTGCACTGCCCACTTCACTGCTCGGAA
GGGGAAGCGACACCACGCCCACGTCAACGTGAGCTGGTGCTTCGTGTGCTCCAAAGGGGGGAGCCTTCTGTGCTGTGAGTCCTGCCCAGC
GGCCTTCCACCCTGACTGCCTGAACATCGAGATGCCTGACGGCAGCTGGTTCTGCAATGACTGCAGGGCTGGGAAGAAGCTGCACTTCCA
GGATATCATTTGGGTGAAACTTGGGAACTACAGATGGTGGCCGGCAGAAGTTTGCCATCCCAAAAATGTTCCCCCAAATATTCAGAAAAT
GAAGCACGAGATTGGAGAATTCCCTGTGTTTTTCTTTGGGTCTAAAGATTATTACTGGACGCATCAGGCGCGAGTGTTCCCGTACATGGA
GGGGGACCGGGGCAGCCGCTACCAGGGGGTCAGAGGGATCGGAAGAGTCTTCAAAAACGGTCAAAAGGCTGAGTTTCAAATTCTGGATAA
TGTAGACTCAACGGGAGAGTTGATAGTGAGATTACCCAAAGAAATAACAATTTCAGGCAGTTTCCAGGGCTTCCACCATCAGAAAATCAA
GATATCGGAGAACCGGATATCCCAGCAGTATCTGGCTACCCTTGAAAACAGGAAGCTGAAGAGGGAACTACCCTTTTCATTCCGATCAAT
TAATACGAGAGAAAACCTGTATCTGGTGACAGAAACTCTGGAGACGGTAAAGGAGGAAACCCTGAAAAGCGACCGGCAATATAAATTTTG
GAGCCAGATCTCTCAGGGCCATCTCAGCTATAAACACAAGGGCCAAAGGGAAGTGACCATCCCCCCAAATCGGGTCCTGAGCTATCGAGT
AAAGCAGCTTGTCTTCCCCAACAAGGAGACGATGAAGAAGGATGGTGCTTCATCCTGTTTAGGAAAGTCTTTGGGTTCGGAGGATTCCAG
AAACATGAAGGAGAAGTTGGAGGACATGGAGAGTGTCCTCAAGGACCTGACAGAGGAGAAGAGAAAAGATGTGCTAAACTCCCTCGCTAA
GTGCCTCGGCAAGGAGGATATTCGGCAGGATCTAGAGCAAAGAGTATCTGAGGTCCTGATTTCCGGGGAGCTACACATGGAGGACCCAGA
CAAGCCTCTCCTAAGCAGCCTTTTTAATGCTGCTGGGGTCTTGGTAGAAGCGCGTGCAAAAGCCATTCTGGACTTCCTGGATGCCCTGCT
AGAGCTGTCTGAAGAGCAGCAGTTTGTGGCTGAGGCCCTGGAGAAGGGGACCCTTCCTCTGTTGAAGGACCAGGTGAAATCTGTCATGGA
GCAGAACTGGGATGAGCTGGCCAGCAGTCCTCCTGACATGGACTATGACCCTGAGGCACGAATTCTCTGTGCGCTGTATGTTGTTGTCTC
TATCCTGCTGGAGCTGGCTGAGGGGCCTACCTCTGTCTCTTCCTAACTACAAAAGCCCTTTCTCCCCACAAGCCTCTGGGTTTTCCCTTT
ACCAGTCTGTCCTCACTGCCATCGCCACTACCATCCTGTCACCAGTGGGACCTCTTTAAAACAAGCAGCCAACCATTCTTTGATGTATCC

>99189_99189_25_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000508803_GSDMB_chr17_38068750_ENST00000309481_length(amino acids)=1288AA_BP=963
MGWMEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEGVMQKFNGHDALPFIPADKLKDLTSRVF
NGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNGSPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDS
LLEQGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFF
GDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNP
QVAKEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGKSTPQKTAEADPRRGVGSPPGRKKTTVS
MPRSRKGDAASQFLVFCQKHRDEVVAEHPDASGEEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTE
DAEAEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKRNRASTAASSALGFSKSSSPSASLTENE
VSDSPGDEPSESPYESADETQTEVSVSSKKSERGVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSC
FVCKESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKGKMMRCVRCPVAYHSGDACLAAGCSVIA
SNSIICTAHFTARKGKRHHAHVNVSWCFVCSKGGSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAE
VCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKNGQKAEFQILDNVDSTGELIVRLPKEIT
ISGSFQGFHHQKIKISENRISQQYLATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWSQISQGHLSYKHKGQR
EVTIPPNRVLSYRVKQLVFPNKETMKKDGASSCLGKSLGSEDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVS
EVLISGELHMEDPDKPLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQNWDELASSPPDMDYD

--------------------------------------------------------------
>99189_99189_26_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000508803_GSDMB_chr17_38068750_ENST00000360317_length(transcript)=4262nt_BP=3029nt
CGCTGCGCCCGCCGCCGCCGCCGCCCCCTCCCCGCCTGGGCCCTACCGCCGCACGGCCCCGGCCCCCTCCCAGCCTGCCGCTCCGGAGAG
CCGCCCGCCGAGGATGCGACGCACCGCAGTGTTCTAAGAACGGAAGCATCTGGGCTGGATGGAATTTAGCATCAAGCAGAGTCCCCTTTC
TGTTCAGAGTGTTGTAAAGTGCATAAAGATGAAGCAGGCACCAGAAATCCTCGGCAGTGCCAACGGGAAGACTCCGAGCTGCGAGGTGAA
CCGCGAGTGTTCTGTGTTCCTCAGCAAAGCCCAGCTCTCCAGTAGCCTGCAGGAGGGGGTCATGCAGAAGTTTAACGGCCACGACGCCCT
GCCCTTTATTCCAGCCGACAAGCTGAAAGATCTTACTTCCCGGGTGTTTAATGGAGAACCCGGCGCACACGATGCCAAACTGCGTTTTGA
GTCCCAGGAAATGAAAGGGATTGGGACACCCCCTAACACTACCCCTATCAAAAATGGCTCTCCAGAAATTAAGCTGAAAATCACCAAAAC
ATACATGAATGGGAAGCCTCTCTTTGAATCTTCCATTTGTGGTGACAGTGCTGCTGATGTGTCTCAGTCAGAAGAAAATGGACAAAAACC
AGAAAACAAGGCGAGAAGGAACAGGAAGAGGAGCATAAAATATGACTCCTTGCTGGAGCAGGGCCTTGTCGAAGCAGCTCTTGTGTCTAA
GATCTCAAGTCCTTCAGATAAAAAGATTCCAGCTAAGAAAGAGTCTTGTCCAAACACTGGAAGAGACAAAGACCACCTGTTGAAATACAA
CGTTGGTGATTTGGTGTGGTCCAAAGTGTCGGGTTACCCTTGGTGGCCTTGCATGGTTTCTGCAGATCCACTCCTTCACAGCTATACCAA
ACTTAAAGGTCAGAAAAAGAGTGCACGCCAGTATCACGTACAGTTCTTTGGTGACGCCCCAGAAAGAGCTTGGATATTTGAGAAGAGCCT
CGTAGCTTTTGAAGGAGAAGGACAGTTTGAAAAATTATGCCAGGAAAGTGCCAAGCAGGCACCCACGAAAGCTGAGAAAATTAAGCTATT
GAAACCAATTTCAGGGAAATTGAGGGCCCAGTGGGAAATGGGCATTGTTCAAGCAGAAGAAGCTGCAAGCATGTCAGTGGAGGAGCGGAA
AGCCAAGTTCACCTTTCTCTATGTGGGGGACCAGCTTCATCTCAACCCTCAAGTAGCCAAGGAGGCTGGCATTGCTGCAGAGTCTTTGGG
AGAAATGGCAGAATCCTCAGGAGTCAGTGAAGAAGCTGCTGAAAACCCCAAGTCTGTGAGAGAAGAGTGCATTCCCATGAAGAGAAGGCG
GAGGGCCAAACTGTGTAGCTCTGCAGAGACCCTGGAGAGTCACCCCGACATAGGGAAGAGTACTCCTCAAAAGACGGCAGAGGCTGACCC
CAGAAGAGGAGTAGGGTCTCCTCCTGGGAGGAAGAAGACCACAGTCTCCATGCCACGAAGCAGGAAGGGAGATGCAGCATCCCAGTTTTT
GGTCTTCTGTCAAAAACACAGGGATGAGGTGGTAGCTGAGCACCCAGATGCTTCAGGTGAGGAGATTGAAGAGCTGCTCAGGTCACAGTG
GAGTCTGCTGAGTGAGAAGCAGAGAGCACGCTACAACACCAAGTTTGCCCTGGTGGCCCCTGTCCAGGCTGAAGAAGACTCTGGTAATGT
AAATGGGAAAAAAAGAAACCACACAAAGAGGATACAGGACCCTACAGAAGATGCTGAAGCTGAGGACACACCCAGGAAAAGACTCAGGAC
GGACAAGCACAGTCTTCGGAAGAGAGACACAATCACTGACAAAACGGCCAGAACAAGCTCTTACAAGGCCATGGAGGCAGCCTCCTCGCT
CAAGAGCCAGGCAGCAACGAAAAATCTGTCTGATGCATGTAAACCACTGAAGAAGCGAAATCGGGCTTCCACGGCAGCATCTTCAGCTCT
TGGGTTTAGCAAAAGTTCATCTCCTTCTGCATCCTTAACTGAGAATGAGGTCTCGGACAGCCCGGGAGACGAGCCCTCGGAGTCCCCATA
CGAAAGTGCAGACGAAACACAAACTGAAGTATCTGTCTCATCCAAAAAGTCTGAGCGAGGAGTGACTGCCAAAAAGGAGTATGTGTGCCA
GCTGTGTGAGAAGCCGGGCAGCCTCCTGCTCTGTGAAGGACCCTGCTGCGGAGCTTTCCACCTCGCCTGCCTTGGGCTTTCCCGGAGGCC
AGAAGGGAGGTTCACCTGCAGCGAGTGTGCCTCAGGGATTCACTCATGTTTCGTGTGTAAAGAGAGCAAGACAGATGTTAAGCGCTGTGT
GGTAACTCAGTGTGGAAAATTTTACCATGAGGCTTGTGTGAAAAAATACCCTCTGACTGTATTTGAGAGCCGAGGTTTCCGCTGCCCCCT
CCACAGCTGTGTGAGCTGCCATGCTTCCAACCCTTCAAACCCAAGGCCGTCAAAAGGTAAAATGATGCGGTGTGTCCGCTGCCCCGTTGC
CTATCACAGCGGGGATGCTTGTCTGGCAGCAGGATGCTCAGTGATCGCCTCCAACAGCATCATCTGCACTGCCCACTTCACTGCTCGGAA
GGGGAAGCGACACCACGCCCACGTCAACGTGAGCTGGTGCTTCGTGTGCTCCAAAGGGGGGAGCCTTCTGTGCTGTGAGTCCTGCCCAGC
GGCCTTCCACCCTGACTGCCTGAACATCGAGATGCCTGACGGCAGCTGGTTCTGCAATGACTGCAGGGCTGGGAAGAAGCTGCACTTCCA
GGATATCATTTGGGTGAAACTTGGGAACTACAGATGGTGGCCGGCAGAAGTTTGCCATCCCAAAAATGTTCCCCCAAATATTCAGAAAAT
GAAGCACGAGATTGGAGAATTCCCTGTGTTTTTCTTTGGGTCTAAAGATTATTACTGGACGCATCAGGCGCGAGTGTTCCCGTACATGGA
GGGGGACCGGGGCAGCCGCTACCAGGGGGTCAGAGGGATCGGAAGAGTCTTCAAAAACGGTCAAAAGGCTGAGTTTCAAATTCTGGATAA
TGTAGACTCAACGGGAGAGTTGATAGTGAGATTACCCAAAGAAATAACAATTTCAGGCAGTTTCCAGGGCTTCCACCATCAGAAAATCAA
GATATCGGAGAACCGGATATCCCAGCAGTATCTGGCTACCCTTGAAAACAGGAAGCTGAAGAGGGAACTACCCTTTTCATTCCGATCAAT
TAATACGAGAGAAAACCTGTATCTGGTGACAGAAACTCTGGAGACGGTAAAGGAGGAAACCCTGAAAAGCGACCGGCAATATAAATTTTG
GAGCCAGATCTCTCAGGGCCATCTCAGCTATAAACACAAGGGCCAAAGGGAAGTGACCATCCCCCCAAATCGGGTCCTGAGCTATCGAGT
AAAGCAGCTTGTCTTCCCCAACAAGGAGACGATGAATATTCATTTCAGGGGCAAAACAAAATCCTTTCCAGAAGAGAAGGATGGTGCTTC
ATCCTGTTTAGGAAAGTCTTTGGGTTCGGAGGATTCCAGAAACATGAAGGAGAAGTTGGAGGACATGGAGAGTGTCCTCAAGGACCTGAC
AGAGGAGAAGAGAAAAGATGTGCTAAACTCCCTCGCTAAGTGCCTCGGCAAGGAGGATATTCGGCAGGATCTAGAGCAAAGAGTATCTGA
GGTCCTGATTTCCGGGGAGCTACACATGGAGGACCCAGACAAGCCTCTCCTAAGCAGCCTTTTTAATGCTGCTGGGGTCTTGGTAGAAGC
GCGTGCAAAAGCCATTCTGGACTTCCTGGATGCCCTGCTAGAGCTGTCTGAAGAGCAGCAGTTTGTGGCTGAGGCCCTGGAGAAGGGGAC
CCTTCCTCTGTTGAAGGACCAGGTGAAATCTGTCATGGAGCAGAACTGGGATGAGCTGGCCAGCAGTCCTCCTGACATGGACTATGACCC
TGAGGCACGAATTCTCTGTGCGCTGTATGTTGTTGTCTCTATCCTGCTGGAGCTGGCTGAGGGGCCTACCTCTGTCTCTTCCTAACTACA
AAAGCCCTTTCTCCCCACAAGCCTCTGGGTTTTCCCTTTACCAGTCTGTCCTCACTGCCATCGCCACTACCATCCTGTCACCAGTGGGAC
CTCTTTAAAACAAGCAGCCAACCATTCTTTGATGTATCCCATTCGCTCCATGTTAACATCCAAAACCAGCCTGGATTTCATACATGGACT

>99189_99189_26_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000508803_GSDMB_chr17_38068750_ENST00000360317_length(amino acids)=1301AA_BP=963
MGWMEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEGVMQKFNGHDALPFIPADKLKDLTSRVF
NGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNGSPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDS
LLEQGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFF
GDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNP
QVAKEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGKSTPQKTAEADPRRGVGSPPGRKKTTVS
MPRSRKGDAASQFLVFCQKHRDEVVAEHPDASGEEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTE
DAEAEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKRNRASTAASSALGFSKSSSPSASLTENE
VSDSPGDEPSESPYESADETQTEVSVSSKKSERGVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSC
FVCKESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKGKMMRCVRCPVAYHSGDACLAAGCSVIA
SNSIICTAHFTARKGKRHHAHVNVSWCFVCSKGGSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAE
VCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKNGQKAEFQILDNVDSTGELIVRLPKEIT
ISGSFQGFHHQKIKISENRISQQYLATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWSQISQGHLSYKHKGQR
EVTIPPNRVLSYRVKQLVFPNKETMNIHFRGKTKSFPEEKDGASSCLGKSLGSEDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLG
KEDIRQDLEQRVSEVLISGELHMEDPDKPLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQNW

--------------------------------------------------------------
>99189_99189_27_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000508803_GSDMB_chr17_38068750_ENST00000394175_length(transcript)=4196nt_BP=3029nt
CGCTGCGCCCGCCGCCGCCGCCGCCCCCTCCCCGCCTGGGCCCTACCGCCGCACGGCCCCGGCCCCCTCCCAGCCTGCCGCTCCGGAGAG
CCGCCCGCCGAGGATGCGACGCACCGCAGTGTTCTAAGAACGGAAGCATCTGGGCTGGATGGAATTTAGCATCAAGCAGAGTCCCCTTTC
TGTTCAGAGTGTTGTAAAGTGCATAAAGATGAAGCAGGCACCAGAAATCCTCGGCAGTGCCAACGGGAAGACTCCGAGCTGCGAGGTGAA
CCGCGAGTGTTCTGTGTTCCTCAGCAAAGCCCAGCTCTCCAGTAGCCTGCAGGAGGGGGTCATGCAGAAGTTTAACGGCCACGACGCCCT
GCCCTTTATTCCAGCCGACAAGCTGAAAGATCTTACTTCCCGGGTGTTTAATGGAGAACCCGGCGCACACGATGCCAAACTGCGTTTTGA
GTCCCAGGAAATGAAAGGGATTGGGACACCCCCTAACACTACCCCTATCAAAAATGGCTCTCCAGAAATTAAGCTGAAAATCACCAAAAC
ATACATGAATGGGAAGCCTCTCTTTGAATCTTCCATTTGTGGTGACAGTGCTGCTGATGTGTCTCAGTCAGAAGAAAATGGACAAAAACC
AGAAAACAAGGCGAGAAGGAACAGGAAGAGGAGCATAAAATATGACTCCTTGCTGGAGCAGGGCCTTGTCGAAGCAGCTCTTGTGTCTAA
GATCTCAAGTCCTTCAGATAAAAAGATTCCAGCTAAGAAAGAGTCTTGTCCAAACACTGGAAGAGACAAAGACCACCTGTTGAAATACAA
CGTTGGTGATTTGGTGTGGTCCAAAGTGTCGGGTTACCCTTGGTGGCCTTGCATGGTTTCTGCAGATCCACTCCTTCACAGCTATACCAA
ACTTAAAGGTCAGAAAAAGAGTGCACGCCAGTATCACGTACAGTTCTTTGGTGACGCCCCAGAAAGAGCTTGGATATTTGAGAAGAGCCT
CGTAGCTTTTGAAGGAGAAGGACAGTTTGAAAAATTATGCCAGGAAAGTGCCAAGCAGGCACCCACGAAAGCTGAGAAAATTAAGCTATT
GAAACCAATTTCAGGGAAATTGAGGGCCCAGTGGGAAATGGGCATTGTTCAAGCAGAAGAAGCTGCAAGCATGTCAGTGGAGGAGCGGAA
AGCCAAGTTCACCTTTCTCTATGTGGGGGACCAGCTTCATCTCAACCCTCAAGTAGCCAAGGAGGCTGGCATTGCTGCAGAGTCTTTGGG
AGAAATGGCAGAATCCTCAGGAGTCAGTGAAGAAGCTGCTGAAAACCCCAAGTCTGTGAGAGAAGAGTGCATTCCCATGAAGAGAAGGCG
GAGGGCCAAACTGTGTAGCTCTGCAGAGACCCTGGAGAGTCACCCCGACATAGGGAAGAGTACTCCTCAAAAGACGGCAGAGGCTGACCC
CAGAAGAGGAGTAGGGTCTCCTCCTGGGAGGAAGAAGACCACAGTCTCCATGCCACGAAGCAGGAAGGGAGATGCAGCATCCCAGTTTTT
GGTCTTCTGTCAAAAACACAGGGATGAGGTGGTAGCTGAGCACCCAGATGCTTCAGGTGAGGAGATTGAAGAGCTGCTCAGGTCACAGTG
GAGTCTGCTGAGTGAGAAGCAGAGAGCACGCTACAACACCAAGTTTGCCCTGGTGGCCCCTGTCCAGGCTGAAGAAGACTCTGGTAATGT
AAATGGGAAAAAAAGAAACCACACAAAGAGGATACAGGACCCTACAGAAGATGCTGAAGCTGAGGACACACCCAGGAAAAGACTCAGGAC
GGACAAGCACAGTCTTCGGAAGAGAGACACAATCACTGACAAAACGGCCAGAACAAGCTCTTACAAGGCCATGGAGGCAGCCTCCTCGCT
CAAGAGCCAGGCAGCAACGAAAAATCTGTCTGATGCATGTAAACCACTGAAGAAGCGAAATCGGGCTTCCACGGCAGCATCTTCAGCTCT
TGGGTTTAGCAAAAGTTCATCTCCTTCTGCATCCTTAACTGAGAATGAGGTCTCGGACAGCCCGGGAGACGAGCCCTCGGAGTCCCCATA
CGAAAGTGCAGACGAAACACAAACTGAAGTATCTGTCTCATCCAAAAAGTCTGAGCGAGGAGTGACTGCCAAAAAGGAGTATGTGTGCCA
GCTGTGTGAGAAGCCGGGCAGCCTCCTGCTCTGTGAAGGACCCTGCTGCGGAGCTTTCCACCTCGCCTGCCTTGGGCTTTCCCGGAGGCC
AGAAGGGAGGTTCACCTGCAGCGAGTGTGCCTCAGGGATTCACTCATGTTTCGTGTGTAAAGAGAGCAAGACAGATGTTAAGCGCTGTGT
GGTAACTCAGTGTGGAAAATTTTACCATGAGGCTTGTGTGAAAAAATACCCTCTGACTGTATTTGAGAGCCGAGGTTTCCGCTGCCCCCT
CCACAGCTGTGTGAGCTGCCATGCTTCCAACCCTTCAAACCCAAGGCCGTCAAAAGGTAAAATGATGCGGTGTGTCCGCTGCCCCGTTGC
CTATCACAGCGGGGATGCTTGTCTGGCAGCAGGATGCTCAGTGATCGCCTCCAACAGCATCATCTGCACTGCCCACTTCACTGCTCGGAA
GGGGAAGCGACACCACGCCCACGTCAACGTGAGCTGGTGCTTCGTGTGCTCCAAAGGGGGGAGCCTTCTGTGCTGTGAGTCCTGCCCAGC
GGCCTTCCACCCTGACTGCCTGAACATCGAGATGCCTGACGGCAGCTGGTTCTGCAATGACTGCAGGGCTGGGAAGAAGCTGCACTTCCA
GGATATCATTTGGGTGAAACTTGGGAACTACAGATGGTGGCCGGCAGAAGTTTGCCATCCCAAAAATGTTCCCCCAAATATTCAGAAAAT
GAAGCACGAGATTGGAGAATTCCCTGTGTTTTTCTTTGGGTCTAAAGATTATTACTGGACGCATCAGGCGCGAGTGTTCCCGTACATGGA
GGGGGACCGGGGCAGCCGCTACCAGGGGGTCAGAGGGATCGGAAGAGTCTTCAAAAACGGTCAAAAGGCTGAGTTTCAAATTCTGGATAA
TGTAGACTCAACGGGAGAGTTGATAGTGAGATTACCCAAAGAAATAACAATTTCAGGCAGTTTCCAGGGCTTCCACCATCAGAAAATCAA
GATATCGGAGAACCGGATATCCCAGCAGTATCTGGCTACCCTTGAAAACAGGAAGCTGAAGAGGGAACTACCCTTTTCATTCCGATCAAT
TAATACGAGAGAAAACCTGTATCTGGTGACAGAAACTCTGGAGACGGTAAAGGAGGAAACCCTGAAAAGCGACCGGCAATATAAATTTTG
GAGCCAGATCTCTCAGGGCCATCTCAGCTATAAACACAAGGGCCAAAGGGAAGTGACCATCCCCCCAAATCGGGTCCTGAGCTATCGAGT
AAAGCAGCTTGTCTTCCCCAACAAGGAGACGATGAGAAAGTCTTTGGGTTCGGAGGATTCCAGAAACATGAAGGAGAAGTTGGAGGACAT
GGAGAGTGTCCTCAAGGACCTGACAGAGGAGAAGAGAAAAGATGTGCTAAACTCCCTCGCTAAGTGCCTCGGCAAGGAGGATATTCGGCA
GGATCTAGAGCAAAGAGTATCTGAGGTCCTGATTTCCGGGGAGCTACACATGGAGGACCCAGACAAGCCTCTCCTAAGCAGCCTTTTTAA
TGCTGCTGGGGTCTTGGTAGAAGCGCGTGCAAAAGCCATTCTGGACTTCCTGGATGCCCTGCTAGAGCTGTCTGAAGAGCAGCAGTTTGT
GGCTGAGGCCCTGGAGAAGGGGACCCTTCCTCTGTTGAAGGACCAGGTGAAATCTGTCATGGAGCAGAACTGGGATGAGCTGGCCAGCAG
TCCTCCTGACATGGACTATGACCCTGAGGCACGAATTCTCTGTGCGCTGTATGTTGTTGTCTCTATCCTGCTGGAGCTGGCTGAGGGGCC
TACCTCTGTCTCTTCCTAACTACAAAAGCCCTTTCTCCCCACAAGCCTCTGGGTTTTCCCTTTACCAGTCTGTCCTCACTGCCATCGCCA
CTACCATCCTGTCACCAGTGGGACCTCTTTAAAACAAGCAGCCAACCATTCTTTGATGTATCCCATTCGCTCCATGTTAACATCCAAAAC

>99189_99189_27_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000508803_GSDMB_chr17_38068750_ENST00000394175_length(amino acids)=1279AA_BP=963
MGWMEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEGVMQKFNGHDALPFIPADKLKDLTSRVF
NGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNGSPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDS
LLEQGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFF
GDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNP
QVAKEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGKSTPQKTAEADPRRGVGSPPGRKKTTVS
MPRSRKGDAASQFLVFCQKHRDEVVAEHPDASGEEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTE
DAEAEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKRNRASTAASSALGFSKSSSPSASLTENE
VSDSPGDEPSESPYESADETQTEVSVSSKKSERGVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSC
FVCKESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKGKMMRCVRCPVAYHSGDACLAAGCSVIA
SNSIICTAHFTARKGKRHHAHVNVSWCFVCSKGGSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAE
VCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKNGQKAEFQILDNVDSTGELIVRLPKEIT
ISGSFQGFHHQKIKISENRISQQYLATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWSQISQGHLSYKHKGQR
EVTIPPNRVLSYRVKQLVFPNKETMRKSLGSEDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELH
MEDPDKPLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQNWDELASSPPDMDYDPEARILCAL

--------------------------------------------------------------
>99189_99189_28_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000508803_GSDMB_chr17_38068750_ENST00000394179_length(transcript)=4245nt_BP=3029nt
CGCTGCGCCCGCCGCCGCCGCCGCCCCCTCCCCGCCTGGGCCCTACCGCCGCACGGCCCCGGCCCCCTCCCAGCCTGCCGCTCCGGAGAG
CCGCCCGCCGAGGATGCGACGCACCGCAGTGTTCTAAGAACGGAAGCATCTGGGCTGGATGGAATTTAGCATCAAGCAGAGTCCCCTTTC
TGTTCAGAGTGTTGTAAAGTGCATAAAGATGAAGCAGGCACCAGAAATCCTCGGCAGTGCCAACGGGAAGACTCCGAGCTGCGAGGTGAA
CCGCGAGTGTTCTGTGTTCCTCAGCAAAGCCCAGCTCTCCAGTAGCCTGCAGGAGGGGGTCATGCAGAAGTTTAACGGCCACGACGCCCT
GCCCTTTATTCCAGCCGACAAGCTGAAAGATCTTACTTCCCGGGTGTTTAATGGAGAACCCGGCGCACACGATGCCAAACTGCGTTTTGA
GTCCCAGGAAATGAAAGGGATTGGGACACCCCCTAACACTACCCCTATCAAAAATGGCTCTCCAGAAATTAAGCTGAAAATCACCAAAAC
ATACATGAATGGGAAGCCTCTCTTTGAATCTTCCATTTGTGGTGACAGTGCTGCTGATGTGTCTCAGTCAGAAGAAAATGGACAAAAACC
AGAAAACAAGGCGAGAAGGAACAGGAAGAGGAGCATAAAATATGACTCCTTGCTGGAGCAGGGCCTTGTCGAAGCAGCTCTTGTGTCTAA
GATCTCAAGTCCTTCAGATAAAAAGATTCCAGCTAAGAAAGAGTCTTGTCCAAACACTGGAAGAGACAAAGACCACCTGTTGAAATACAA
CGTTGGTGATTTGGTGTGGTCCAAAGTGTCGGGTTACCCTTGGTGGCCTTGCATGGTTTCTGCAGATCCACTCCTTCACAGCTATACCAA
ACTTAAAGGTCAGAAAAAGAGTGCACGCCAGTATCACGTACAGTTCTTTGGTGACGCCCCAGAAAGAGCTTGGATATTTGAGAAGAGCCT
CGTAGCTTTTGAAGGAGAAGGACAGTTTGAAAAATTATGCCAGGAAAGTGCCAAGCAGGCACCCACGAAAGCTGAGAAAATTAAGCTATT
GAAACCAATTTCAGGGAAATTGAGGGCCCAGTGGGAAATGGGCATTGTTCAAGCAGAAGAAGCTGCAAGCATGTCAGTGGAGGAGCGGAA
AGCCAAGTTCACCTTTCTCTATGTGGGGGACCAGCTTCATCTCAACCCTCAAGTAGCCAAGGAGGCTGGCATTGCTGCAGAGTCTTTGGG
AGAAATGGCAGAATCCTCAGGAGTCAGTGAAGAAGCTGCTGAAAACCCCAAGTCTGTGAGAGAAGAGTGCATTCCCATGAAGAGAAGGCG
GAGGGCCAAACTGTGTAGCTCTGCAGAGACCCTGGAGAGTCACCCCGACATAGGGAAGAGTACTCCTCAAAAGACGGCAGAGGCTGACCC
CAGAAGAGGAGTAGGGTCTCCTCCTGGGAGGAAGAAGACCACAGTCTCCATGCCACGAAGCAGGAAGGGAGATGCAGCATCCCAGTTTTT
GGTCTTCTGTCAAAAACACAGGGATGAGGTGGTAGCTGAGCACCCAGATGCTTCAGGTGAGGAGATTGAAGAGCTGCTCAGGTCACAGTG
GAGTCTGCTGAGTGAGAAGCAGAGAGCACGCTACAACACCAAGTTTGCCCTGGTGGCCCCTGTCCAGGCTGAAGAAGACTCTGGTAATGT
AAATGGGAAAAAAAGAAACCACACAAAGAGGATACAGGACCCTACAGAAGATGCTGAAGCTGAGGACACACCCAGGAAAAGACTCAGGAC
GGACAAGCACAGTCTTCGGAAGAGAGACACAATCACTGACAAAACGGCCAGAACAAGCTCTTACAAGGCCATGGAGGCAGCCTCCTCGCT
CAAGAGCCAGGCAGCAACGAAAAATCTGTCTGATGCATGTAAACCACTGAAGAAGCGAAATCGGGCTTCCACGGCAGCATCTTCAGCTCT
TGGGTTTAGCAAAAGTTCATCTCCTTCTGCATCCTTAACTGAGAATGAGGTCTCGGACAGCCCGGGAGACGAGCCCTCGGAGTCCCCATA
CGAAAGTGCAGACGAAACACAAACTGAAGTATCTGTCTCATCCAAAAAGTCTGAGCGAGGAGTGACTGCCAAAAAGGAGTATGTGTGCCA
GCTGTGTGAGAAGCCGGGCAGCCTCCTGCTCTGTGAAGGACCCTGCTGCGGAGCTTTCCACCTCGCCTGCCTTGGGCTTTCCCGGAGGCC
AGAAGGGAGGTTCACCTGCAGCGAGTGTGCCTCAGGGATTCACTCATGTTTCGTGTGTAAAGAGAGCAAGACAGATGTTAAGCGCTGTGT
GGTAACTCAGTGTGGAAAATTTTACCATGAGGCTTGTGTGAAAAAATACCCTCTGACTGTATTTGAGAGCCGAGGTTTCCGCTGCCCCCT
CCACAGCTGTGTGAGCTGCCATGCTTCCAACCCTTCAAACCCAAGGCCGTCAAAAGGTAAAATGATGCGGTGTGTCCGCTGCCCCGTTGC
CTATCACAGCGGGGATGCTTGTCTGGCAGCAGGATGCTCAGTGATCGCCTCCAACAGCATCATCTGCACTGCCCACTTCACTGCTCGGAA
GGGGAAGCGACACCACGCCCACGTCAACGTGAGCTGGTGCTTCGTGTGCTCCAAAGGGGGGAGCCTTCTGTGCTGTGAGTCCTGCCCAGC
GGCCTTCCACCCTGACTGCCTGAACATCGAGATGCCTGACGGCAGCTGGTTCTGCAATGACTGCAGGGCTGGGAAGAAGCTGCACTTCCA
GGATATCATTTGGGTGAAACTTGGGAACTACAGATGGTGGCCGGCAGAAGTTTGCCATCCCAAAAATGTTCCCCCAAATATTCAGAAAAT
GAAGCACGAGATTGGAGAATTCCCTGTGTTTTTCTTTGGGTCTAAAGATTATTACTGGACGCATCAGGCGCGAGTGTTCCCGTACATGGA
GGGGGACCGGGGCAGCCGCTACCAGGGGGTCAGAGGGATCGGAAGAGTCTTCAAAAACGGTCAAAAGGCTGAGTTTCAAATTCTGGATAA
TGTAGACTCAACGGGAGAGTTGATAGTGAGATTACCCAAAGAAATAACAATTTCAGGCAGTTTCCAGGGCTTCCACCATCAGAAAATCAA
GATATCGGAGAACCGGATATCCCAGCAGTATCTGGCTACCCTTGAAAACAGGAAGCTGAAGAGGGAACTACCCTTTTCATTCCGATCAAT
TAATACGAGAGAAAACCTGTATCTGGTGACAGAAACTCTGGAGACGGTAAAGGAGGAAACCCTGAAAAGCGACCGGCAATATAAATTTTG
GAGCCAGATCTCTCAGGGCCATCTCAGCTATAAACACAAGGGCCAAAGGGAAGTGACCATCCCCCCAAATCGGGTCCTGAGCTATCGAGT
AAAGCAGCTTGTCTTCCCCAACAAGGAGACGATGAGTGCTGGTTTAGATATTCATTTCAGGGGCAAAACAAAATCCTTTCCAGAAGGAAA
GTCTTTGGGTTCGGAGGATTCCAGAAACATGAAGGAGAAGTTGGAGGACATGGAGAGTGTCCTCAAGGACCTGACAGAGGAGAAGAGAAA
AGATGTGCTAAACTCCCTCGCTAAGTGCCTCGGCAAGGAGGATATTCGGCAGGATCTAGAGCAAAGAGTATCTGAGGTCCTGATTTCCGG
GGAGCTACACATGGAGGACCCAGACAAGCCTCTCCTAAGCAGCCTTTTTAATGCTGCTGGGGTCTTGGTAGAAGCGCGTGCAAAAGCCAT
TCTGGACTTCCTGGATGCCCTGCTAGAGCTGTCTGAAGAGCAGCAGTTTGTGGCTGAGGCCCTGGAGAAGGGGACCCTTCCTCTGTTGAA
GGACCAGGTGAAATCTGTCATGGAGCAGAACTGGGATGAGCTGGCCAGCAGTCCTCCTGACATGGACTATGACCCTGAGGCACGAATTCT
CTGTGCGCTGTATGTTGTTGTCTCTATCCTGCTGGAGCTGGCTGAGGGGCCTACCTCTGTCTCTTCCTAACTACAAAAGCCCTTTCTCCC
CACAAGCCTCTGGGTTTTCCCTTTACCAGTCTGTCCTCACTGCCATCGCCACTACCATCCTGTCACCAGTGGGACCTCTTTAAAACAAGC
AGCCAACCATTCTTTGATGTATCCCATTCGCTCCATGTTAACATCCAAAACCAGCCTGGATTTCATACATGGACTTCTGATTAAAAGTGG

>99189_99189_28_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000508803_GSDMB_chr17_38068750_ENST00000394179_length(amino acids)=1296AA_BP=963
MGWMEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEGVMQKFNGHDALPFIPADKLKDLTSRVF
NGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNGSPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDS
LLEQGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFF
GDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNP
QVAKEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGKSTPQKTAEADPRRGVGSPPGRKKTTVS
MPRSRKGDAASQFLVFCQKHRDEVVAEHPDASGEEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTE
DAEAEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKRNRASTAASSALGFSKSSSPSASLTENE
VSDSPGDEPSESPYESADETQTEVSVSSKKSERGVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSC
FVCKESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKGKMMRCVRCPVAYHSGDACLAAGCSVIA
SNSIICTAHFTARKGKRHHAHVNVSWCFVCSKGGSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAE
VCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKNGQKAEFQILDNVDSTGELIVRLPKEIT
ISGSFQGFHHQKIKISENRISQQYLATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWSQISQGHLSYKHKGQR
EVTIPPNRVLSYRVKQLVFPNKETMSAGLDIHFRGKTKSFPEGKSLGSEDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIR
QDLEQRVSEVLISGELHMEDPDKPLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQNWDELAS

--------------------------------------------------------------
>99189_99189_29_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000508803_GSDMB_chr17_38068750_ENST00000418519_length(transcript)=4260nt_BP=3029nt
CGCTGCGCCCGCCGCCGCCGCCGCCCCCTCCCCGCCTGGGCCCTACCGCCGCACGGCCCCGGCCCCCTCCCAGCCTGCCGCTCCGGAGAG
CCGCCCGCCGAGGATGCGACGCACCGCAGTGTTCTAAGAACGGAAGCATCTGGGCTGGATGGAATTTAGCATCAAGCAGAGTCCCCTTTC
TGTTCAGAGTGTTGTAAAGTGCATAAAGATGAAGCAGGCACCAGAAATCCTCGGCAGTGCCAACGGGAAGACTCCGAGCTGCGAGGTGAA
CCGCGAGTGTTCTGTGTTCCTCAGCAAAGCCCAGCTCTCCAGTAGCCTGCAGGAGGGGGTCATGCAGAAGTTTAACGGCCACGACGCCCT
GCCCTTTATTCCAGCCGACAAGCTGAAAGATCTTACTTCCCGGGTGTTTAATGGAGAACCCGGCGCACACGATGCCAAACTGCGTTTTGA
GTCCCAGGAAATGAAAGGGATTGGGACACCCCCTAACACTACCCCTATCAAAAATGGCTCTCCAGAAATTAAGCTGAAAATCACCAAAAC
ATACATGAATGGGAAGCCTCTCTTTGAATCTTCCATTTGTGGTGACAGTGCTGCTGATGTGTCTCAGTCAGAAGAAAATGGACAAAAACC
AGAAAACAAGGCGAGAAGGAACAGGAAGAGGAGCATAAAATATGACTCCTTGCTGGAGCAGGGCCTTGTCGAAGCAGCTCTTGTGTCTAA
GATCTCAAGTCCTTCAGATAAAAAGATTCCAGCTAAGAAAGAGTCTTGTCCAAACACTGGAAGAGACAAAGACCACCTGTTGAAATACAA
CGTTGGTGATTTGGTGTGGTCCAAAGTGTCGGGTTACCCTTGGTGGCCTTGCATGGTTTCTGCAGATCCACTCCTTCACAGCTATACCAA
ACTTAAAGGTCAGAAAAAGAGTGCACGCCAGTATCACGTACAGTTCTTTGGTGACGCCCCAGAAAGAGCTTGGATATTTGAGAAGAGCCT
CGTAGCTTTTGAAGGAGAAGGACAGTTTGAAAAATTATGCCAGGAAAGTGCCAAGCAGGCACCCACGAAAGCTGAGAAAATTAAGCTATT
GAAACCAATTTCAGGGAAATTGAGGGCCCAGTGGGAAATGGGCATTGTTCAAGCAGAAGAAGCTGCAAGCATGTCAGTGGAGGAGCGGAA
AGCCAAGTTCACCTTTCTCTATGTGGGGGACCAGCTTCATCTCAACCCTCAAGTAGCCAAGGAGGCTGGCATTGCTGCAGAGTCTTTGGG
AGAAATGGCAGAATCCTCAGGAGTCAGTGAAGAAGCTGCTGAAAACCCCAAGTCTGTGAGAGAAGAGTGCATTCCCATGAAGAGAAGGCG
GAGGGCCAAACTGTGTAGCTCTGCAGAGACCCTGGAGAGTCACCCCGACATAGGGAAGAGTACTCCTCAAAAGACGGCAGAGGCTGACCC
CAGAAGAGGAGTAGGGTCTCCTCCTGGGAGGAAGAAGACCACAGTCTCCATGCCACGAAGCAGGAAGGGAGATGCAGCATCCCAGTTTTT
GGTCTTCTGTCAAAAACACAGGGATGAGGTGGTAGCTGAGCACCCAGATGCTTCAGGTGAGGAGATTGAAGAGCTGCTCAGGTCACAGTG
GAGTCTGCTGAGTGAGAAGCAGAGAGCACGCTACAACACCAAGTTTGCCCTGGTGGCCCCTGTCCAGGCTGAAGAAGACTCTGGTAATGT
AAATGGGAAAAAAAGAAACCACACAAAGAGGATACAGGACCCTACAGAAGATGCTGAAGCTGAGGACACACCCAGGAAAAGACTCAGGAC
GGACAAGCACAGTCTTCGGAAGAGAGACACAATCACTGACAAAACGGCCAGAACAAGCTCTTACAAGGCCATGGAGGCAGCCTCCTCGCT
CAAGAGCCAGGCAGCAACGAAAAATCTGTCTGATGCATGTAAACCACTGAAGAAGCGAAATCGGGCTTCCACGGCAGCATCTTCAGCTCT
TGGGTTTAGCAAAAGTTCATCTCCTTCTGCATCCTTAACTGAGAATGAGGTCTCGGACAGCCCGGGAGACGAGCCCTCGGAGTCCCCATA
CGAAAGTGCAGACGAAACACAAACTGAAGTATCTGTCTCATCCAAAAAGTCTGAGCGAGGAGTGACTGCCAAAAAGGAGTATGTGTGCCA
GCTGTGTGAGAAGCCGGGCAGCCTCCTGCTCTGTGAAGGACCCTGCTGCGGAGCTTTCCACCTCGCCTGCCTTGGGCTTTCCCGGAGGCC
AGAAGGGAGGTTCACCTGCAGCGAGTGTGCCTCAGGGATTCACTCATGTTTCGTGTGTAAAGAGAGCAAGACAGATGTTAAGCGCTGTGT
GGTAACTCAGTGTGGAAAATTTTACCATGAGGCTTGTGTGAAAAAATACCCTCTGACTGTATTTGAGAGCCGAGGTTTCCGCTGCCCCCT
CCACAGCTGTGTGAGCTGCCATGCTTCCAACCCTTCAAACCCAAGGCCGTCAAAAGGTAAAATGATGCGGTGTGTCCGCTGCCCCGTTGC
CTATCACAGCGGGGATGCTTGTCTGGCAGCAGGATGCTCAGTGATCGCCTCCAACAGCATCATCTGCACTGCCCACTTCACTGCTCGGAA
GGGGAAGCGACACCACGCCCACGTCAACGTGAGCTGGTGCTTCGTGTGCTCCAAAGGGGGGAGCCTTCTGTGCTGTGAGTCCTGCCCAGC
GGCCTTCCACCCTGACTGCCTGAACATCGAGATGCCTGACGGCAGCTGGTTCTGCAATGACTGCAGGGCTGGGAAGAAGCTGCACTTCCA
GGATATCATTTGGGTGAAACTTGGGAACTACAGATGGTGGCCGGCAGAAGTTTGCCATCCCAAAAATGTTCCCCCAAATATTCAGAAAAT
GAAGCACGAGATTGGAGAATTCCCTGTGTTTTTCTTTGGGTCTAAAGATTATTACTGGACGCATCAGGCGCGAGTGTTCCCGTACATGGA
GGGGGACCGGGGCAGCCGCTACCAGGGGGTCAGAGGGATCGGAAGAGTCTTCAAAAACGGTCAAAAGGCTGAGTTTCAAATTCTGGATAA
TGTAGACTCAACGGGAGAGTTGATAGTGAGATTACCCAAAGAAATAACAATTTCAGGCAGTTTCCAGGGCTTCCACCATCAGAAAATCAA
GATATCGGAGAACCGGATATCCCAGCAGTATCTGGCTACCCTTGAAAACAGGAAGCTGAAGAGGGAACTACCCTTTTCATTCCGATCAAT
TAATACGAGAGAAAACCTGTATCTGGTGACAGAAACTCTGGAGACGGTAAAGGAGGAAACCCTGAAAAGCGACCGGCAATATAAATTTTG
GAGCCAGATCTCTCAGGGCCATCTCAGCTATAAACACAAGGGCCAAAGGGAAGTGACCATCCCCCCAAATCGGGTCCTGAGCTATCGAGT
AAAGCAGCTTGTCTTCCCCAACAAGGAGACGATGAATATTCATTTCAGGGGCAAAACAAAATCCTTTCCAGAAGAGAAGGATGGTGCTTC
ATCCTGTTTAGGAAAGTCTTTGGGTTCGGAGGATTCCAGAAACATGAAGGAGAAGTTGGAGGACATGGAGAGTGTCCTCAAGGACCTGAC
AGAGGAGAAGAGAAAAGATGTGCTAAACTCCCTCGCTAAGTGCCTCGGCAAGGAGGATATTCGGCAGGATCTAGAGCAAAGAGTATCTGA
GGTCCTGATTTCCGGGGAGCTACACATGGAGGACCCAGACAAGCCTCTCCTAAGCAGCCTTTTTAATGCTGCTGGGGTCTTGGTAGAAGC
GCGTGCAAAAGCCATTCTGGACTTCCTGGATGCCCTGCTAGAGCTGTCTGAAGAGCAGCAGTTTGTGGCTGAGGCCCTGGAGAAGGGGAC
CCTTCCTCTGTTGAAGGACCAGGTGAAATCTGTCATGGAGCAGAACTGGGATGAGCTGGCCAGCAGTCCTCCTGACATGGACTATGACCC
TGAGGCACGAATTCTCTGTGCGCTGTATGTTGTTGTCTCTATCCTGCTGGAGCTGGCTGAGGGGCCTACCTCTGTCTCTTCCTAACTACA
AAAGCCCTTTCTCCCCACAAGCCTCTGGGTTTTCCCTTTACCAGTCTGTCCTCACTGCCATCGCCACTACCATCCTGTCACCAGTGGGAC
CTCTTTAAAACAAGCAGCCAACCATTCTTTGATGTATCCCATTCGCTCCATGTTAACATCCAAAACCAGCCTGGATTTCATACATGGACT

>99189_99189_29_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000508803_GSDMB_chr17_38068750_ENST00000418519_length(amino acids)=1301AA_BP=963
MGWMEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEGVMQKFNGHDALPFIPADKLKDLTSRVF
NGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNGSPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDS
LLEQGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFF
GDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNP
QVAKEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGKSTPQKTAEADPRRGVGSPPGRKKTTVS
MPRSRKGDAASQFLVFCQKHRDEVVAEHPDASGEEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTE
DAEAEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKRNRASTAASSALGFSKSSSPSASLTENE
VSDSPGDEPSESPYESADETQTEVSVSSKKSERGVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSC
FVCKESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKGKMMRCVRCPVAYHSGDACLAAGCSVIA
SNSIICTAHFTARKGKRHHAHVNVSWCFVCSKGGSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAE
VCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKNGQKAEFQILDNVDSTGELIVRLPKEIT
ISGSFQGFHHQKIKISENRISQQYLATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWSQISQGHLSYKHKGQR
EVTIPPNRVLSYRVKQLVFPNKETMNIHFRGKTKSFPEEKDGASSCLGKSLGSEDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLG
KEDIRQDLEQRVSEVLISGELHMEDPDKPLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQNW

--------------------------------------------------------------
>99189_99189_30_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000508803_GSDMB_chr17_38068750_ENST00000520542_length(transcript)=4233nt_BP=3029nt
CGCTGCGCCCGCCGCCGCCGCCGCCCCCTCCCCGCCTGGGCCCTACCGCCGCACGGCCCCGGCCCCCTCCCAGCCTGCCGCTCCGGAGAG
CCGCCCGCCGAGGATGCGACGCACCGCAGTGTTCTAAGAACGGAAGCATCTGGGCTGGATGGAATTTAGCATCAAGCAGAGTCCCCTTTC
TGTTCAGAGTGTTGTAAAGTGCATAAAGATGAAGCAGGCACCAGAAATCCTCGGCAGTGCCAACGGGAAGACTCCGAGCTGCGAGGTGAA
CCGCGAGTGTTCTGTGTTCCTCAGCAAAGCCCAGCTCTCCAGTAGCCTGCAGGAGGGGGTCATGCAGAAGTTTAACGGCCACGACGCCCT
GCCCTTTATTCCAGCCGACAAGCTGAAAGATCTTACTTCCCGGGTGTTTAATGGAGAACCCGGCGCACACGATGCCAAACTGCGTTTTGA
GTCCCAGGAAATGAAAGGGATTGGGACACCCCCTAACACTACCCCTATCAAAAATGGCTCTCCAGAAATTAAGCTGAAAATCACCAAAAC
ATACATGAATGGGAAGCCTCTCTTTGAATCTTCCATTTGTGGTGACAGTGCTGCTGATGTGTCTCAGTCAGAAGAAAATGGACAAAAACC
AGAAAACAAGGCGAGAAGGAACAGGAAGAGGAGCATAAAATATGACTCCTTGCTGGAGCAGGGCCTTGTCGAAGCAGCTCTTGTGTCTAA
GATCTCAAGTCCTTCAGATAAAAAGATTCCAGCTAAGAAAGAGTCTTGTCCAAACACTGGAAGAGACAAAGACCACCTGTTGAAATACAA
CGTTGGTGATTTGGTGTGGTCCAAAGTGTCGGGTTACCCTTGGTGGCCTTGCATGGTTTCTGCAGATCCACTCCTTCACAGCTATACCAA
ACTTAAAGGTCAGAAAAAGAGTGCACGCCAGTATCACGTACAGTTCTTTGGTGACGCCCCAGAAAGAGCTTGGATATTTGAGAAGAGCCT
CGTAGCTTTTGAAGGAGAAGGACAGTTTGAAAAATTATGCCAGGAAAGTGCCAAGCAGGCACCCACGAAAGCTGAGAAAATTAAGCTATT
GAAACCAATTTCAGGGAAATTGAGGGCCCAGTGGGAAATGGGCATTGTTCAAGCAGAAGAAGCTGCAAGCATGTCAGTGGAGGAGCGGAA
AGCCAAGTTCACCTTTCTCTATGTGGGGGACCAGCTTCATCTCAACCCTCAAGTAGCCAAGGAGGCTGGCATTGCTGCAGAGTCTTTGGG
AGAAATGGCAGAATCCTCAGGAGTCAGTGAAGAAGCTGCTGAAAACCCCAAGTCTGTGAGAGAAGAGTGCATTCCCATGAAGAGAAGGCG
GAGGGCCAAACTGTGTAGCTCTGCAGAGACCCTGGAGAGTCACCCCGACATAGGGAAGAGTACTCCTCAAAAGACGGCAGAGGCTGACCC
CAGAAGAGGAGTAGGGTCTCCTCCTGGGAGGAAGAAGACCACAGTCTCCATGCCACGAAGCAGGAAGGGAGATGCAGCATCCCAGTTTTT
GGTCTTCTGTCAAAAACACAGGGATGAGGTGGTAGCTGAGCACCCAGATGCTTCAGGTGAGGAGATTGAAGAGCTGCTCAGGTCACAGTG
GAGTCTGCTGAGTGAGAAGCAGAGAGCACGCTACAACACCAAGTTTGCCCTGGTGGCCCCTGTCCAGGCTGAAGAAGACTCTGGTAATGT
AAATGGGAAAAAAAGAAACCACACAAAGAGGATACAGGACCCTACAGAAGATGCTGAAGCTGAGGACACACCCAGGAAAAGACTCAGGAC
GGACAAGCACAGTCTTCGGAAGAGAGACACAATCACTGACAAAACGGCCAGAACAAGCTCTTACAAGGCCATGGAGGCAGCCTCCTCGCT
CAAGAGCCAGGCAGCAACGAAAAATCTGTCTGATGCATGTAAACCACTGAAGAAGCGAAATCGGGCTTCCACGGCAGCATCTTCAGCTCT
TGGGTTTAGCAAAAGTTCATCTCCTTCTGCATCCTTAACTGAGAATGAGGTCTCGGACAGCCCGGGAGACGAGCCCTCGGAGTCCCCATA
CGAAAGTGCAGACGAAACACAAACTGAAGTATCTGTCTCATCCAAAAAGTCTGAGCGAGGAGTGACTGCCAAAAAGGAGTATGTGTGCCA
GCTGTGTGAGAAGCCGGGCAGCCTCCTGCTCTGTGAAGGACCCTGCTGCGGAGCTTTCCACCTCGCCTGCCTTGGGCTTTCCCGGAGGCC
AGAAGGGAGGTTCACCTGCAGCGAGTGTGCCTCAGGGATTCACTCATGTTTCGTGTGTAAAGAGAGCAAGACAGATGTTAAGCGCTGTGT
GGTAACTCAGTGTGGAAAATTTTACCATGAGGCTTGTGTGAAAAAATACCCTCTGACTGTATTTGAGAGCCGAGGTTTCCGCTGCCCCCT
CCACAGCTGTGTGAGCTGCCATGCTTCCAACCCTTCAAACCCAAGGCCGTCAAAAGGTAAAATGATGCGGTGTGTCCGCTGCCCCGTTGC
CTATCACAGCGGGGATGCTTGTCTGGCAGCAGGATGCTCAGTGATCGCCTCCAACAGCATCATCTGCACTGCCCACTTCACTGCTCGGAA
GGGGAAGCGACACCACGCCCACGTCAACGTGAGCTGGTGCTTCGTGTGCTCCAAAGGGGGGAGCCTTCTGTGCTGTGAGTCCTGCCCAGC
GGCCTTCCACCCTGACTGCCTGAACATCGAGATGCCTGACGGCAGCTGGTTCTGCAATGACTGCAGGGCTGGGAAGAAGCTGCACTTCCA
GGATATCATTTGGGTGAAACTTGGGAACTACAGATGGTGGCCGGCAGAAGTTTGCCATCCCAAAAATGTTCCCCCAAATATTCAGAAAAT
GAAGCACGAGATTGGAGAATTCCCTGTGTTTTTCTTTGGGTCTAAAGATTATTACTGGACGCATCAGGCGCGAGTGTTCCCGTACATGGA
GGGGGACCGGGGCAGCCGCTACCAGGGGGTCAGAGGGATCGGAAGAGTCTTCAAAAACGGTCAAAAGGCTGAGTTTCAAATTCTGGATAA
TGTAGACTCAACGGGAGAGTTGATAGTGAGATTACCCAAAGAAATAACAATTTCAGGCAGTTTCCAGGGCTTCCACCATCAGAAAATCAA
GATATCGGAGAACCGGATATCCCAGCAGTATCTGGCTACCCTTGAAAACAGGAAGCTGAAGAGGGAACTACCCTTTTCATTCCGATCAAT
TAATACGAGAGAAAACCTGTATCTGGTGACAGAAACTCTGGAGACGGTAAAGGAGGAAACCCTGAAAAGCGACCGGCAATATAAATTTTG
GAGCCAGATCTCTCAGGGCCATCTCAGCTATAAACACAAGGGCCAAAGGGAAGTGACCATCCCCCCAAATCGGGTCCTGAGCTATCGAGT
AAAGCAGCTTGTCTTCCCCAACAAGGAGACGATGAATATTCATTTCAGGGGCAAAACAAAATCCTTTCCAGAAGGAAAGTCTTTGGGTTC
GGAGGATTCCAGAAACATGAAGGAGAAGTTGGAGGACATGGAGAGTGTCCTCAAGGACCTGACAGAGGAGAAGAGAAAAGATGTGCTAAA
CTCCCTCGCTAAGTGCCTCGGCAAGGAGGATATTCGGCAGGATCTAGAGCAAAGAGTATCTGAGGTCCTGATTTCCGGGGAGCTACACAT
GGAGGACCCAGACAAGCCTCTCCTAAGCAGCCTTTTTAATGCTGCTGGGGTCTTGGTAGAAGCGCGTGCAAAAGCCATTCTGGACTTCCT
GGATGCCCTGCTAGAGCTGTCTGAAGAGCAGCAGTTTGTGGCTGAGGCCCTGGAGAAGGGGACCCTTCCTCTGTTGAAGGACCAGGTGAA
ATCTGTCATGGAGCAGAACTGGGATGAGCTGGCCAGCAGTCCTCCTGACATGGACTATGACCCTGAGGCACGAATTCTCTGTGCGCTGTA
TGTTGTTGTCTCTATCCTGCTGGAGCTGGCTGAGGGGCCTACCTCTGTCTCTTCCTAACTACAAAAGCCCTTTCTCCCCACAAGCCTCTG
GGTTTTCCCTTTACCAGTCTGTCCTCACTGCCATCGCCACTACCATCCTGTCACCAGTGGGACCTCTTTAAAACAAGCAGCCAACCATTC
TTTGATGTATCCCATTCGCTCCATGTTAACATCCAAAACCAGCCTGGATTTCATACATGGACTTCTGATTAAAAGTGGCAGGTTGTGCAT

>99189_99189_30_WHSC1-GSDMB_WHSC1_chr4_1957915_ENST00000508803_GSDMB_chr17_38068750_ENST00000520542_length(amino acids)=1292AA_BP=963
MGWMEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEGVMQKFNGHDALPFIPADKLKDLTSRVF
NGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNGSPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDS
LLEQGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFF
GDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNP
QVAKEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGKSTPQKTAEADPRRGVGSPPGRKKTTVS
MPRSRKGDAASQFLVFCQKHRDEVVAEHPDASGEEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTE
DAEAEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKRNRASTAASSALGFSKSSSPSASLTENE
VSDSPGDEPSESPYESADETQTEVSVSSKKSERGVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSC
FVCKESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKGKMMRCVRCPVAYHSGDACLAAGCSVIA
SNSIICTAHFTARKGKRHHAHVNVSWCFVCSKGGSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAE
VCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKNGQKAEFQILDNVDSTGELIVRLPKEIT
ISGSFQGFHHQKIKISENRISQQYLATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWSQISQGHLSYKHKGQR
EVTIPPNRVLSYRVKQLVFPNKETMNIHFRGKTKSFPEGKSLGSEDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLE
QRVSEVLISGELHMEDPDKPLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQNWDELASSPPD

--------------------------------------------------------------

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Fusion Gene PPI Analysis for WHSC1-GSDMB


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for WHSC1-GSDMB


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for WHSC1-GSDMB


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource