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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:WHSC1L1-ADAM18 (FusionGDB2 ID:99193)

Fusion Gene Summary for WHSC1L1-ADAM18

check button Fusion gene summary
Fusion gene informationFusion gene name: WHSC1L1-ADAM18
Fusion gene ID: 99193
HgeneTgene
Gene symbol

WHSC1L1

ADAM18

Gene ID

54904

8749

Gene namenuclear receptor binding SET domain protein 3ADAM metallopeptidase domain 18
SynonymsKMT3F|KMT3G|WHISTLE|WHSC1L1|pp14328ADAM27|tMDCIII
Cytomap

8p11.23

8p11.22

Type of geneprotein-codingprotein-coding
Descriptionhistone-lysine N-methyltransferase NSD3WHSC1-like 1 isoform 9 with methyltransferase activity to lysineWolf-Hirschhorn syndrome candidate 1-like 1nuclear SET domain-containing protein 3protein whistledisintegrin and metalloproteinase domain-containing protein 18a disintegrin and metalloproteinase domain 18transmembrane metalloproteinase-like, disintegrin-like, and cysteine-rich protein III
Modification date2020031320200313
UniProtAcc.

Q9Y3Q7

Ensembl transtripts involved in fusion geneENST00000317025, ENST00000433384, 
ENST00000527502, ENST00000316985, 
ENST00000525081, 		ENST00000523755, 
ENST00000520772, ENST00000541111, 
ENST00000379866, ENST00000265707, 
Fusion gene scores* DoF score31 X 27 X 13=108818 X 8 X 6=384
# samples 469
** MAII scorelog2(46/10881*10)=-4.56403347974706
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(9/384*10)=-2.09310940439148
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: WHSC1L1 [Title/Abstract] AND ADAM18 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointWHSC1L1(38137058)-ADAM18(39587417), # samples:2
Anticipated loss of major functional domain due to fusion event.WHSC1L1-ADAM18 seems lost the major protein functional domain in Hgene partner, which is a epigenetic factor due to the frame-shifted ORF.
WHSC1L1-ADAM18 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
WHSC1L1-ADAM18 seems lost the major protein functional domain in Hgene partner, which is a tumor suppressor due to the frame-shifted ORF.
WHSC1L1-ADAM18 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneWHSC1L1

GO:0016571

histone methylation

16682010


check buttonFusion gene breakpoints across WHSC1L1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ADAM18 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4COADTCGA-D5-6926-01AWHSC1L1chr8

38137058

-ADAM18chr8

39587417

+
ChimerDB4COADTCGA-D5-6926WHSC1L1chr8

38137057

-ADAM18chr8

39587416

+


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Fusion Gene ORF analysis for WHSC1L1-ADAM18

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000317025ENST00000523755WHSC1L1chr8

38137058

-ADAM18chr8

39587417

+
5CDS-3UTRENST00000317025ENST00000523755WHSC1L1chr8

38137057

-ADAM18chr8

39587416

+
5CDS-3UTRENST00000433384ENST00000523755WHSC1L1chr8

38137058

-ADAM18chr8

39587417

+
5CDS-3UTRENST00000433384ENST00000523755WHSC1L1chr8

38137057

-ADAM18chr8

39587416

+
5CDS-3UTRENST00000527502ENST00000523755WHSC1L1chr8

38137058

-ADAM18chr8

39587417

+
5CDS-3UTRENST00000527502ENST00000523755WHSC1L1chr8

38137057

-ADAM18chr8

39587416

+
5CDS-intronENST00000317025ENST00000520772WHSC1L1chr8

38137058

-ADAM18chr8

39587417

+
5CDS-intronENST00000317025ENST00000520772WHSC1L1chr8

38137057

-ADAM18chr8

39587416

+
5CDS-intronENST00000317025ENST00000541111WHSC1L1chr8

38137058

-ADAM18chr8

39587417

+
5CDS-intronENST00000317025ENST00000541111WHSC1L1chr8

38137057

-ADAM18chr8

39587416

+
5CDS-intronENST00000433384ENST00000520772WHSC1L1chr8

38137058

-ADAM18chr8

39587417

+
5CDS-intronENST00000433384ENST00000520772WHSC1L1chr8

38137057

-ADAM18chr8

39587416

+
5CDS-intronENST00000433384ENST00000541111WHSC1L1chr8

38137058

-ADAM18chr8

39587417

+
5CDS-intronENST00000433384ENST00000541111WHSC1L1chr8

38137057

-ADAM18chr8

39587416

+
5CDS-intronENST00000527502ENST00000520772WHSC1L1chr8

38137058

-ADAM18chr8

39587417

+
5CDS-intronENST00000527502ENST00000520772WHSC1L1chr8

38137057

-ADAM18chr8

39587416

+
5CDS-intronENST00000527502ENST00000541111WHSC1L1chr8

38137058

-ADAM18chr8

39587417

+
5CDS-intronENST00000527502ENST00000541111WHSC1L1chr8

38137057

-ADAM18chr8

39587416

+
Frame-shiftENST00000317025ENST00000379866WHSC1L1chr8

38137058

-ADAM18chr8

39587417

+
Frame-shiftENST00000317025ENST00000379866WHSC1L1chr8

38137057

-ADAM18chr8

39587416

+
Frame-shiftENST00000433384ENST00000379866WHSC1L1chr8

38137058

-ADAM18chr8

39587417

+
Frame-shiftENST00000433384ENST00000379866WHSC1L1chr8

38137057

-ADAM18chr8

39587416

+
Frame-shiftENST00000527502ENST00000379866WHSC1L1chr8

38137058

-ADAM18chr8

39587417

+
Frame-shiftENST00000527502ENST00000379866WHSC1L1chr8

38137057

-ADAM18chr8

39587416

+
In-frameENST00000317025ENST00000265707WHSC1L1chr8

38137058

-ADAM18chr8

39587417

+
In-frameENST00000317025ENST00000265707WHSC1L1chr8

38137057

-ADAM18chr8

39587416

+
In-frameENST00000433384ENST00000265707WHSC1L1chr8

38137058

-ADAM18chr8

39587417

+
In-frameENST00000433384ENST00000265707WHSC1L1chr8

38137057

-ADAM18chr8

39587416

+
In-frameENST00000527502ENST00000265707WHSC1L1chr8

38137058

-ADAM18chr8

39587417

+
In-frameENST00000527502ENST00000265707WHSC1L1chr8

38137057

-ADAM18chr8

39587416

+
intron-3CDSENST00000316985ENST00000265707WHSC1L1chr8

38137058

-ADAM18chr8

39587417

+
intron-3CDSENST00000316985ENST00000265707WHSC1L1chr8

38137057

-ADAM18chr8

39587416

+
intron-3CDSENST00000316985ENST00000379866WHSC1L1chr8

38137058

-ADAM18chr8

39587417

+
intron-3CDSENST00000316985ENST00000379866WHSC1L1chr8

38137057

-ADAM18chr8

39587416

+
intron-3CDSENST00000525081ENST00000265707WHSC1L1chr8

38137058

-ADAM18chr8

39587417

+
intron-3CDSENST00000525081ENST00000265707WHSC1L1chr8

38137057

-ADAM18chr8

39587416

+
intron-3CDSENST00000525081ENST00000379866WHSC1L1chr8

38137058

-ADAM18chr8

39587417

+
intron-3CDSENST00000525081ENST00000379866WHSC1L1chr8

38137057

-ADAM18chr8

39587416

+
intron-3UTRENST00000316985ENST00000523755WHSC1L1chr8

38137058

-ADAM18chr8

39587417

+
intron-3UTRENST00000316985ENST00000523755WHSC1L1chr8

38137057

-ADAM18chr8

39587416

+
intron-3UTRENST00000525081ENST00000523755WHSC1L1chr8

38137058

-ADAM18chr8

39587417

+
intron-3UTRENST00000525081ENST00000523755WHSC1L1chr8

38137057

-ADAM18chr8

39587416

+
intron-intronENST00000316985ENST00000520772WHSC1L1chr8

38137058

-ADAM18chr8

39587417

+
intron-intronENST00000316985ENST00000520772WHSC1L1chr8

38137057

-ADAM18chr8

39587416

+
intron-intronENST00000316985ENST00000541111WHSC1L1chr8

38137058

-ADAM18chr8

39587417

+
intron-intronENST00000316985ENST00000541111WHSC1L1chr8

38137057

-ADAM18chr8

39587416

+
intron-intronENST00000525081ENST00000520772WHSC1L1chr8

38137058

-ADAM18chr8

39587417

+
intron-intronENST00000525081ENST00000520772WHSC1L1chr8

38137057

-ADAM18chr8

39587416

+
intron-intronENST00000525081ENST00000541111WHSC1L1chr8

38137058

-ADAM18chr8

39587417

+
intron-intronENST00000525081ENST00000541111WHSC1L1chr8

38137057

-ADAM18chr8

39587416

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000317025WHSC1L1chr838137057-ENST00000265707ADAM18chr839587416+4444427851843481276
ENST00000433384WHSC1L1chr838137057-ENST00000265707ADAM18chr839587416+4270410449141741227
ENST00000527502WHSC1L1chr838137057-ENST00000265707ADAM18chr839587416+398538199238891265
ENST00000317025WHSC1L1chr838137058-ENST00000265707ADAM18chr839587417+4444427851843481276
ENST00000433384WHSC1L1chr838137058-ENST00000265707ADAM18chr839587417+4270410449141741227
ENST00000527502WHSC1L1chr838137058-ENST00000265707ADAM18chr839587417+398538199238891265

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000317025ENST00000265707WHSC1L1chr838137057-ADAM18chr839587416+0.0009716080.99902844
ENST00000433384ENST00000265707WHSC1L1chr838137057-ADAM18chr839587416+0.0009693820.9990306
ENST00000527502ENST00000265707WHSC1L1chr838137057-ADAM18chr839587416+0.0006523980.9993476
ENST00000317025ENST00000265707WHSC1L1chr838137058-ADAM18chr839587417+0.0009716080.99902844
ENST00000433384ENST00000265707WHSC1L1chr838137058-ADAM18chr839587417+0.0009693820.9990306
ENST00000527502ENST00000265707WHSC1L1chr838137058-ADAM18chr839587417+0.0006523980.9993476

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Fusion Genomic Features for WHSC1L1-ADAM18


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
WHSC1L1chr838137057-ADAM18chr839587416+0.0004803440.9995197
WHSC1L1chr838137057-ADAM18chr839587416+0.0004803440.9995197
WHSC1L1chr838137057-ADAM18chr839587416+0.0004803440.9995197
WHSC1L1chr838137057-ADAM18chr839587416+0.0004803440.9995197

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for WHSC1L1-ADAM18


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr8:38137058/chr8:39587417)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.ADAM18

Q9Y3Q7

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Sperm surface membrane protein that may be involved in spermatogenesis and fertilization. This is a non catalytic metalloprotease-like protein (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneWHSC1L1chr8:38137057chr8:39587416ENST00000317025-21241033_106912531438.0Coiled coilOntology_term=ECO:0000255
HgeneWHSC1L1chr8:38137057chr8:39587416ENST00000433384-20231033_106912041389.0Coiled coilOntology_term=ECO:0000255
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000317025-21241033_106912531438.0Coiled coilOntology_term=ECO:0000255
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000433384-20231033_106912041389.0Coiled coilOntology_term=ECO:0000255
HgeneWHSC1L1chr8:38137057chr8:39587416ENST00000317025-21241093_114312531438.0DomainAWS
HgeneWHSC1L1chr8:38137057chr8:39587416ENST00000317025-2124270_33312531438.0DomainPWWP 1
HgeneWHSC1L1chr8:38137057chr8:39587416ENST00000317025-2124960_102212531438.0DomainPWWP 2
HgeneWHSC1L1chr8:38137057chr8:39587416ENST00000433384-20231093_114312041389.0DomainAWS
HgeneWHSC1L1chr8:38137057chr8:39587416ENST00000433384-2023270_33312041389.0DomainPWWP 1
HgeneWHSC1L1chr8:38137057chr8:39587416ENST00000433384-2023960_102212041389.0DomainPWWP 2
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000317025-21241093_114312531438.0DomainAWS
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000317025-2124270_33312531438.0DomainPWWP 1
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000317025-2124960_102212531438.0DomainPWWP 2
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000433384-20231093_114312041389.0DomainAWS
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000433384-2023270_33312041389.0DomainPWWP 1
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000433384-2023960_102212041389.0DomainPWWP 2
HgeneWHSC1L1chr8:38137057chr8:39587416ENST00000317025-2124701_74812531438.0Zinc fingerPHD-type 1
HgeneWHSC1L1chr8:38137057chr8:39587416ENST00000317025-2124749_80512531438.0Zinc fingerPHD-type 2
HgeneWHSC1L1chr8:38137057chr8:39587416ENST00000317025-2124862_95512531438.0Zinc fingerPHD-type 3
HgeneWHSC1L1chr8:38137057chr8:39587416ENST00000433384-2023701_74812041389.0Zinc fingerPHD-type 1
HgeneWHSC1L1chr8:38137057chr8:39587416ENST00000433384-2023749_80512041389.0Zinc fingerPHD-type 2
HgeneWHSC1L1chr8:38137057chr8:39587416ENST00000433384-2023862_95512041389.0Zinc fingerPHD-type 3
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000317025-2124701_74812531438.0Zinc fingerPHD-type 1
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000317025-2124749_80512531438.0Zinc fingerPHD-type 2
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000317025-2124862_95512531438.0Zinc fingerPHD-type 3
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000433384-2023701_74812041389.0Zinc fingerPHD-type 1
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000433384-2023749_80512041389.0Zinc fingerPHD-type 2
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000433384-2023862_95512041389.0Zinc fingerPHD-type 3
TgeneADAM18chr8:38137057chr8:39587416ENST0000052077206480_6220183.0Compositional biasNote=Cys-rich
TgeneADAM18chr8:38137058chr8:39587417ENST0000052077206480_6220183.0Compositional biasNote=Cys-rich
TgeneADAM18chr8:38137057chr8:39587416ENST0000052077206184_3810183.0DomainPeptidase M12B
TgeneADAM18chr8:38137057chr8:39587416ENST0000052077206390_4790183.0DomainDisintegrin
TgeneADAM18chr8:38137057chr8:39587416ENST0000052077206620_6540183.0DomainNote=EGF-like
TgeneADAM18chr8:38137058chr8:39587417ENST0000052077206184_3810183.0DomainPeptidase M12B
TgeneADAM18chr8:38137058chr8:39587417ENST0000052077206390_4790183.0DomainDisintegrin
TgeneADAM18chr8:38137058chr8:39587417ENST0000052077206620_6540183.0DomainNote=EGF-like
TgeneADAM18chr8:38137057chr8:39587416ENST000003798661719709_739701716.0Topological domainCytoplasmic
TgeneADAM18chr8:38137057chr8:39587416ENST0000052077206177_6870183.0Topological domainExtracellular
TgeneADAM18chr8:38137057chr8:39587416ENST0000052077206709_7390183.0Topological domainCytoplasmic
TgeneADAM18chr8:38137058chr8:39587417ENST000003798661719709_739701716.0Topological domainCytoplasmic
TgeneADAM18chr8:38137058chr8:39587417ENST0000052077206177_6870183.0Topological domainExtracellular
TgeneADAM18chr8:38137058chr8:39587417ENST0000052077206709_7390183.0Topological domainCytoplasmic
TgeneADAM18chr8:38137057chr8:39587416ENST0000052077206688_7080183.0TransmembraneHelical
TgeneADAM18chr8:38137058chr8:39587417ENST0000052077206688_7080183.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneWHSC1L1chr8:38137057chr8:39587416ENST00000316985-1101033_10690646.0Coiled coilOntology_term=ECO:0000255
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000316985-1101033_10690646.0Coiled coilOntology_term=ECO:0000255
HgeneWHSC1L1chr8:38137057chr8:39587416ENST00000316985-1101093_11430646.0DomainAWS
HgeneWHSC1L1chr8:38137057chr8:39587416ENST00000316985-1101145_12620646.0DomainSET
HgeneWHSC1L1chr8:38137057chr8:39587416ENST00000316985-1101269_12850646.0DomainPost-SET
HgeneWHSC1L1chr8:38137057chr8:39587416ENST00000316985-110270_3330646.0DomainPWWP 1
HgeneWHSC1L1chr8:38137057chr8:39587416ENST00000316985-110960_10220646.0DomainPWWP 2
HgeneWHSC1L1chr8:38137057chr8:39587416ENST00000317025-21241145_126212531438.0DomainSET
HgeneWHSC1L1chr8:38137057chr8:39587416ENST00000317025-21241269_128512531438.0DomainPost-SET
HgeneWHSC1L1chr8:38137057chr8:39587416ENST00000433384-20231145_126212041389.0DomainSET
HgeneWHSC1L1chr8:38137057chr8:39587416ENST00000433384-20231269_128512041389.0DomainPost-SET
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000316985-1101093_11430646.0DomainAWS
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000316985-1101145_12620646.0DomainSET
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000316985-1101269_12850646.0DomainPost-SET
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000316985-110270_3330646.0DomainPWWP 1
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000316985-110960_10220646.0DomainPWWP 2
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000317025-21241145_126212531438.0DomainSET
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000317025-21241269_128512531438.0DomainPost-SET
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000433384-20231145_126212041389.0DomainSET
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000433384-20231269_128512041389.0DomainPost-SET
HgeneWHSC1L1chr8:38137057chr8:39587416ENST00000316985-1101321_13680646.0Zinc fingerPHD-type 4%3B atypical
HgeneWHSC1L1chr8:38137057chr8:39587416ENST00000316985-110701_7480646.0Zinc fingerPHD-type 1
HgeneWHSC1L1chr8:38137057chr8:39587416ENST00000316985-110749_8050646.0Zinc fingerPHD-type 2
HgeneWHSC1L1chr8:38137057chr8:39587416ENST00000316985-110862_9550646.0Zinc fingerPHD-type 3
HgeneWHSC1L1chr8:38137057chr8:39587416ENST00000317025-21241321_136812531438.0Zinc fingerPHD-type 4%3B atypical
HgeneWHSC1L1chr8:38137057chr8:39587416ENST00000433384-20231321_136812041389.0Zinc fingerPHD-type 4%3B atypical
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000316985-1101321_13680646.0Zinc fingerPHD-type 4%3B atypical
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000316985-110701_7480646.0Zinc fingerPHD-type 1
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000316985-110749_8050646.0Zinc fingerPHD-type 2
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000316985-110862_9550646.0Zinc fingerPHD-type 3
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000317025-21241321_136812531438.0Zinc fingerPHD-type 4%3B atypical
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000433384-20231321_136812041389.0Zinc fingerPHD-type 4%3B atypical
TgeneADAM18chr8:38137057chr8:39587416ENST000002657071820480_622725740.0Compositional biasNote=Cys-rich
TgeneADAM18chr8:38137057chr8:39587416ENST000003798661719480_622701716.0Compositional biasNote=Cys-rich
TgeneADAM18chr8:38137058chr8:39587417ENST000002657071820480_622725740.0Compositional biasNote=Cys-rich
TgeneADAM18chr8:38137058chr8:39587417ENST000003798661719480_622701716.0Compositional biasNote=Cys-rich
TgeneADAM18chr8:38137057chr8:39587416ENST000002657071820184_381725740.0DomainPeptidase M12B
TgeneADAM18chr8:38137057chr8:39587416ENST000002657071820390_479725740.0DomainDisintegrin
TgeneADAM18chr8:38137057chr8:39587416ENST000002657071820620_654725740.0DomainNote=EGF-like
TgeneADAM18chr8:38137057chr8:39587416ENST000003798661719184_381701716.0DomainPeptidase M12B
TgeneADAM18chr8:38137057chr8:39587416ENST000003798661719390_479701716.0DomainDisintegrin
TgeneADAM18chr8:38137057chr8:39587416ENST000003798661719620_654701716.0DomainNote=EGF-like
TgeneADAM18chr8:38137058chr8:39587417ENST000002657071820184_381725740.0DomainPeptidase M12B
TgeneADAM18chr8:38137058chr8:39587417ENST000002657071820390_479725740.0DomainDisintegrin
TgeneADAM18chr8:38137058chr8:39587417ENST000002657071820620_654725740.0DomainNote=EGF-like
TgeneADAM18chr8:38137058chr8:39587417ENST000003798661719184_381701716.0DomainPeptidase M12B
TgeneADAM18chr8:38137058chr8:39587417ENST000003798661719390_479701716.0DomainDisintegrin
TgeneADAM18chr8:38137058chr8:39587417ENST000003798661719620_654701716.0DomainNote=EGF-like
TgeneADAM18chr8:38137057chr8:39587416ENST000002657071820177_687725740.0Topological domainExtracellular
TgeneADAM18chr8:38137057chr8:39587416ENST000002657071820709_739725740.0Topological domainCytoplasmic
TgeneADAM18chr8:38137057chr8:39587416ENST000003798661719177_687701716.0Topological domainExtracellular
TgeneADAM18chr8:38137058chr8:39587417ENST000002657071820177_687725740.0Topological domainExtracellular
TgeneADAM18chr8:38137058chr8:39587417ENST000002657071820709_739725740.0Topological domainCytoplasmic
TgeneADAM18chr8:38137058chr8:39587417ENST000003798661719177_687701716.0Topological domainExtracellular
TgeneADAM18chr8:38137057chr8:39587416ENST000002657071820688_708725740.0TransmembraneHelical
TgeneADAM18chr8:38137057chr8:39587416ENST000003798661719688_708701716.0TransmembraneHelical
TgeneADAM18chr8:38137058chr8:39587417ENST000002657071820688_708725740.0TransmembraneHelical
TgeneADAM18chr8:38137058chr8:39587417ENST000003798661719688_708701716.0TransmembraneHelical


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Fusion Gene Sequence for WHSC1L1-ADAM18


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>99193_99193_1_WHSC1L1-ADAM18_WHSC1L1_chr8_38137057_ENST00000317025_ADAM18_chr8_39587416_ENST00000265707_length(transcript)=4444nt_BP=4278nt
GGGGGCTTTGTGCGCGGCGGCGGCGGGAGAGGCGGCGGCGGCGGCCAGCACGGAGGCGGAGGCCGAGGGGGCTGTGCACAGGTCGCCGCG
GAGAGGCGTGCGAATTCCGAGCCGAGCGCCGAGGACCGTGCTACCCAGGCCGGGCTGCCAGCCGCAGGCTCCTCTCTGGCAGCAGCGGCG
GCGCGGCGACCCCCGTCCCTCGGCCTCCCCTTCCCATCCCACCTCCCGAGCCTTCCTCTTCCCGCAGCACGCCCGGCCCGGCCCGGCCGT
GGCCCTCCTCAGTGCCGGCCGCCATGGCAGAGGCGTCCGGCGCGGGGAAAATCTAGCCCGGGGATTTCATGCGGCCTAGCTCGGTTCCGC
CTCCTCCTCGCGCGGCCCCAGCGGCTGCCCGCACCCCAGCCCCACTCCGGGCCTCCGTGTCTCTCCTGTGATCGCACTGACACGGCCGGG
GGGTTAGAATGGAACAAACTGAAGGCCCGATGAGAGAAAGGGAAAGTTAAGGATGCTGGAGCAGAACAATGGATTTCTCTTTCTCTTTCA
TGCAAGGGATCATGGGAAACACAATTCAGCAACCACCTCAACTCATTGACTCCGCCAACATCCGTCAGGAGGATGCCTTTGATAACAACA
GTGACATTGCTGAAGATGGTGGCCAGACACCATATGAAGCTACTTTGCAGCAAGGCTTTCAGTACCCAGCTACAACAGAAGATCTTCCTC
CACTCACAAATGGGTATCCATCATCAATCAGTGTGTATGAAACTCAAACCAAATACCAGTCATATAATCAGTATCCTAATGGGTCAGCCA
ATGGCTTTGGTGCAGTTAGAAACTTTAGCCCCACTGACTATTATCATTCAGAAATTCCAAACACAAGACCACATGAAATTCTGGAAAAAC
CTTCCCCTCCACAGCCACCACCTCCTCCTTCGGTACCACAAACTGTGATTCCAAAGAAGACTGGCTCACCTGAAATTAAACTAAAAATAA
CCAAAACTATCCAGAATGGCAGGGAATTGTTTGAGTCTTCCCTTTGTGGAGACCTTTTAAATGAAGTACAGGCAAGTGAGCACACGAAAT
CAAAGCATGAAAGCAGAAAAGAAAAGAGGAAAAAAAGCAACAAGCATGACTCATCAAGATCTGAAGAGCGCAAGTCACACAAAATCCCCA
AATTAGAACCAGAGGAACAAAATAGACCAAATGAGAGGGTTGACACTGTATCAGAAAAACCAAGGGAAGAACCAGTACTAAAAGAGGAAG
CCCCAGTTCAGCCAATACTATCTTCTGTTCCAACAACGGAAGTGTCCACTGGTGTTAAGTTTCAGGTTGGCGATCTTGTGTGGTCCAAGG
TGGGAACCTATCCTTGGTGGCCTTGTATGGTTTCAAGTGATCCCCAGCTTGAGGTTCATACTAAAATTAACACAAGAGGTGCCCGAGAAT
ATCATGTCCAGTTTTTTAGCAACCAGCCAGAGAGGGCGTGGGTTCATGAAAAACGGGTACGAGAGTATAAAGGTCATAAACAGTATGAAG
AATTACTGGCTGAGGCAACCAAACAAGCCAGCAATCACTCTGAGAAACAAAAGATTCGGAAACCCCGACCTCAGAGAGAACGTGCTCAGT
GGGATATTGGCATTGCCCATGCAGAGAAAGCATTGAAAATGACTCGAGAAGAAAGAATAGAACAGTATACTTTTATTTACATTGATAAAC
AGCCTGAAGAGGCTTTATCCCAAGCAAAAAAGAGTGTTGCCTCCAAAACCGAAGTTAAAAAAACCCGACGACCAAGATCTGTGCTGAATA
CTCAGCCAGAACAGACCAATGCAGGGGAGGTGGCCTCCTCACTCTCAAGTACTGAAATTCGGAGACATAGCCAGAGGCGGCACACAAGTG
CGGAAGAGGAAGAGCCACCGCCTGTTAAAATAGCCTGGAAAACTGCGGCAGCAAGGAAATCCTTACCAGCTTCCATTACGATGCACAAAG
GGAGCCTGGATTTGCAGAAGTGTAACATGTCTCCAGTTGTGAAAATTGAACAAGTGTTTGCTCTTCAGAATGCTACAGGGGATGGGAAAT
TTATCGATCAATTTGTTTATTCAACAAAGGGAATTGGTAACAAAACAGAAATAAGTGTCAGGGGGCAAGACAGGCTTATAATTTCTACAC
CAAACCAGAGAAATGAAAAGCCAACGCAGAGTGTATCATCTCCTGAAGCAACATCTGGTTCTACAGGCTCAGTAGAAAAGAAGCAACAGA
GAAGATCAATTAGAACTCGTTCTGAATCAGAGAAATCCACTGAGGTTGTGCCAAAGAAGAAGATCAAAAAGGAGCAGGTTGAAACAGTTC
CTCAGGCTACAGTGAAGACTGGATTACAGAAAGGTGCCAGCGAGATTTCAGATTCCTGTAAACCTCTAAAGAAAAGGAGTCGCGCCTCAA
CTGATGTAGAAATGACTAGTTCAGCATACAGAGACACATCTGACTCCGATTCTAGAGGACTGAGTGACCTGCAGGTAGGCTTTGGAAAGC
AAGTAGATAGCCCTTCAGCTACTGCAGATGCAGACGTTTCTGATGTGCAGTCCATGGATTCAAGTTTGTCGAGAAGAGGCACTGGAATGA
GTAAGAAGGACACTGTATGTCAGATTTGTGAAAGCTCTGGTGACTCTCTGATTCCTTGTGAGGGAGAGTGCTGCAAACACTTTCACCTGG
AGTGCCTGGGATTGGCATCACTTCCTGATAGCAAGTTCATCTGCATGGAATGTAAAACTGGGCAGCACCCATGTTTTTCGTGTAAAGTGT
CTGGTAAAGATGTGAAGCGTTGTTCTGTTGGTGCTTGTGGGAAATTTTATCATGAAGCCTGTGTCCGCAAATTCCCCACTGCCATCTTTG
AATCAAAAGGATTCCGCTGTCCTCAGCACTGCTGCTCTGCCTGCTCTATGGAGAAAGATATCCACAAAGCAAGTAAAGGCCGCATGATGA
GATGTTTAAGATGTCCAGTTGCCTATCACTCTGGAGATGCTTGCATTGCGGCCGGAAGCATGTTAGTATCCTCCTACATTCTCATCTGTA
GTAATCATTCCAAACGGAGCAGTAATTCTTCTGCTGTAAATGTAGGCTTTTGTTTCGTTTGTGCCAGAGGGCTGATAGTTCAGGACCATT
CAGACCCCATGTTCAGTTCATATGCCTATAAGTCCCACTACCTACTGAATGAATCAAATCGTGCTGAGTTGATGAAATTACCTATGATTC
CTTCTTCGTCAGCTTCCAAAAAGAAATGTGAGAAAGGTGGAAGATTGCTCTGCTGTGAATCGTGCCCAGCTTCCTTCCACCCGGAATGCC
TAAGCATAGAAATGCCAGAAGGCTGCTGGAATTGTAATGACTGTAAAGCTGGCAAGAAACTACATTACAAGCAGATTGTTTGGGTCAAAT
TGGGAAATTACAGATGGTGGCCAGCAGAGATCTGCAACCCCAGGTCTGTGCCACTGAACATCCAGGGCCTTAAACATGACTTGGGGGACT
TCCCTGTATTCTTCTTTGGTTCTCATGACTACTACTGGGTACACCAGGGCAGAGTGTTCCCTTATGTTGAAGGAGACAAAAGCTTTGCTG
AAGGGCAGACTAGTATTAACAAGACCTTCAAAAAGGCACTGGAAGAAGCTGCAAAACGTTTCCAGGAATTGAAAGCACAAAGAGAAAGTA
AAGAAGCCCTAGAGATTGAAAAAAACTCAAGAAAACCCCCTCCCTACAAACACATCAAAGCTAACAAAGTAATAGGAAAGGTGCAGATCC
AGGTTGCTGACCTGTCAGAGATTCCCCGCTGTAACTGCAAGCCAGCTGATGAAAACCCTTGTGGCTTGGAATCGGAGTGCCTGAACAGAA
TGTTGCAGTATGAATGCCACCCGCAGGTGTGCCCAGCTGGAGATCGTTGTCAGAACCAGTGCTTTACAAAGAGACTATACCCTGATGCAG
AGATCATCAAAACGGAGCGGAGAGGCTGGGGCCTCAGGACCAAAAGGAGCATTAAGAAGGGTGAATTTGTAAATGAATACGTCGGTGAAT
TAATTGATGAAGAAGAATGCAGATTGCGAATCAAGCGAGCCCACGAGAACAGTGTAACTAATTTTTATATGTTAACTGTTACCAAGGACC
GTATAATTGATGCCGGCCCAAAAGGAAATTATTCTCGCTTCATGAACCACAGTTGTAATCCCAACTGTGAAACACAAAAGTGGACAGTGA
ATGGAGATGTTCGAGTGGGACTATTTGCTCTCTGTGATATTCCTGCAGTAATTCATCCGTTGTATCAGAAAGCGATGACGTGGGACATTA
ATATTGCACAGAACTTCCATAGCAAATAACCTAAAGGAACGAATGTGCTTTATTTATAACCTTACGTTATCCCCAATGCATTGTAAATGT

>99193_99193_1_WHSC1L1-ADAM18_WHSC1L1_chr8_38137057_ENST00000317025_ADAM18_chr8_39587416_ENST00000265707_length(amino acids)=1276AA_BP=1253
MDFSFSFMQGIMGNTIQQPPQLIDSANIRQEDAFDNNSDIAEDGGQTPYEATLQQGFQYPATTEDLPPLTNGYPSSISVYETQTKYQSYN
QYPNGSANGFGAVRNFSPTDYYHSEIPNTRPHEILEKPSPPQPPPPPSVPQTVIPKKTGSPEIKLKITKTIQNGRELFESSLCGDLLNEV
QASEHTKSKHESRKEKRKKSNKHDSSRSEERKSHKIPKLEPEEQNRPNERVDTVSEKPREEPVLKEEAPVQPILSSVPTTEVSTGVKFQV
GDLVWSKVGTYPWWPCMVSSDPQLEVHTKINTRGAREYHVQFFSNQPERAWVHEKRVREYKGHKQYEELLAEATKQASNHSEKQKIRKPR
PQRERAQWDIGIAHAEKALKMTREERIEQYTFIYIDKQPEEALSQAKKSVASKTEVKKTRRPRSVLNTQPEQTNAGEVASSLSSTEIRRH
SQRRHTSAEEEEPPPVKIAWKTAAARKSLPASITMHKGSLDLQKCNMSPVVKIEQVFALQNATGDGKFIDQFVYSTKGIGNKTEISVRGQ
DRLIISTPNQRNEKPTQSVSSPEATSGSTGSVEKKQQRRSIRTRSESEKSTEVVPKKKIKKEQVETVPQATVKTGLQKGASEISDSCKPL
KKRSRASTDVEMTSSAYRDTSDSDSRGLSDLQVGFGKQVDSPSATADADVSDVQSMDSSLSRRGTGMSKKDTVCQICESSGDSLIPCEGE
CCKHFHLECLGLASLPDSKFICMECKTGQHPCFSCKVSGKDVKRCSVGACGKFYHEACVRKFPTAIFESKGFRCPQHCCSACSMEKDIHK
ASKGRMMRCLRCPVAYHSGDACIAAGSMLVSSYILICSNHSKRSSNSSAVNVGFCFVCARGLIVQDHSDPMFSSYAYKSHYLLNESNRAE
LMKLPMIPSSSASKKKCEKGGRLLCCESCPASFHPECLSIEMPEGCWNCNDCKAGKKLHYKQIVWVKLGNYRWWPAEICNPRSVPLNIQG
LKHDLGDFPVFFFGSHDYYWVHQGRVFPYVEGDKSFAEGQTSINKTFKKALEEAAKRFQELKAQRESKEALEIEKNSRKPPPYKHIKANK
VIGKVQIQVADLSEIPRCNCKPADENPCGLESECLNRMLQYECHPQVCPAGDRCQNQCFTKRLYPDAEIIKTERRGWGLRTKRSIKKGEF
VNEYVGELIDEEECRLRIKRAHENSVTNFYMLTVTKDRIIDAGPKGNYSRFMNHSCNPNCETQKWTVNGDVRVGLFALCDIPAVIHPLYQ

--------------------------------------------------------------
>99193_99193_2_WHSC1L1-ADAM18_WHSC1L1_chr8_38137057_ENST00000433384_ADAM18_chr8_39587416_ENST00000265707_length(transcript)=4270nt_BP=4104nt
AGAGGCGGCGGCGGCGGCCAGCACGGAGGCGGAGGCCGAGGGGGCTGTGCACAGGTCGCCGCGGAGAGGCGTGCGAATTCCGAGCCGAGC
GCCGAGGACCGTGCTACCCAGGCCGGGCTGCCAGCCGCAGGCTCCTCTCTGGCAGCAGCGGCGGCGCGGCGACCCCCGTCCCTCGGCCTC
CCCTTCCCATCCCACCTCCCGAGCCTTCCTCTTCCCGCAGCACGCCCGGCCCGGCCCGGCCGTGGCCCTCCTCAGTGCCGGCCGCCATGG
CAGAGGCGTCCGGCGCGGGGAAAATCTAGCCCGGGGATTTCATGCGGCCTAGCTCGGTTCCGCCTCCTCCTCGCGCGGCCCCAGCGGCTG
CCCGCACCCCAGCCCCACTCCGGGCCTCCGTGTCTCTCCTGTGATCGCACTGACACGGCCGGGGGGTTAGAATGGAACAAACTGAAGGCC
CGATGAGAGAAAGGGAAAGTTAAGGATGCTGGAGCAGAACAATGGATTTCTCTTTCTCTTTCATGCAAGGGATCATGGGAAACACAATTC
AGCAACCACCTCAACTCATTGACTCCGCCAACATCCGTCAGGAGGATGCCTTTGATAACAACAGTGACATTGCTGAAGATGGTGGCCAGA
CACCATATGAAGCTACTTTGCAGCAAGGCTTTCAGTACCCAGCTACAACAGAAGATCTTCCTCCACTCACAAATGGGTATCCATCATCAA
TCAGTGTGTATGAAACTCAAACCAAATACCAGTCATATAATCAGTATCCTAATGGGTCAGCCAATGGCTTTGGTGCAGTTAGAAACTTTA
GCCCCACTGACTATTATCATTCAGAAATTCCAAACACAAGACCACATGAAATTCTGGAAAAACCTTCCCCTCCACAGCCACCACCTCCTC
CTTCGGTACCACAAACTGTGATTCCAAAGAAGACTGGCTCACCTGAAATTAAACTAAAAATAACCAAAACTATCCAGAATGGCAGGGAAT
TGTTTGAGTCTTCCCTTTGTGGAGACCTTTTAAATGAAGTACAGGCAAGTGAGCACACGAAATCAAAGCATGAAAGCAGAAAAGAAAAGA
GGAAAAAAAGCAACAAGCATGACTCATCAAGATCTGAAGAGCGCAAGTCACACAAAATCCCCAAATTAGAACCAGAGGAACAAAATAGAC
CAAATGAGAGGGTTGACACTGTATCAGAAAAACCAAGGGAAGAACCAGTACTAAAAGAGGAAGCCCCAGTTCAGCCAATACTATCTTCTG
TTCCAACAACGGAAGTGTCCACTGGTGTTAAGTTTCAGGTTGGCGATCTTGTGTGGTCCAAGGTGGGAACCTATCCTTGGTGGCCTTGTA
TGGTTTCAAGTGATCCCCAGCTTGAGGTTCATACTAAAATTAACACAAGAGGTGCCCGAGAATATCATGTCCAGTTTTTTAGCAACCAGC
CAGAGAGGGCGTGGGTTCATGAAAAACGGGTACGAGAGTATAAAGGTCATAAACAGTATGAAGAATTACTGGCTGAGGCAACCAAACAAG
CCAGCAATCACTCTGAGAAACAAAAGATTCGGAAACCCCGACCTCAGAGAGAACGTGCTCAGTGGGATATTGGCATTGCCCATGCAGAGA
AAGCATTGAAAATGACTCGAGAAGAAAGAATAGAACAGTATACTTTTATTTACATTGATAAACAGCCTGAAGAGGCTTTATCCCAAGCAA
AAAAGAGTGTTGCCTCCAAAACCGAAGTTAAAAAAACCCGACGACCAAGATCTGTGCTGAATACTCAGCCAGAACAGACCAATGCAGGGG
AGGTGGCCTCCTCACTCTCAAGTACTGAAATTCGGAGACATAGCCAGAGGCGGCACACAAGTGCGGAAGAGGAAGAGCCACCGCCTGTTA
AAATAGCCTGGAAAACTGCGGCAGCAAGGAAATCCTTACCAGCTTCCATTACGATGCACAAAGGGAGCCTGGATTTGCAGAAGTGTAACA
TGTCTCCAGTTGTGAAAATTGAACAAGTGTTTGCTCTTCAGAATGCTACAGGGGATGGGAAATTTATCGATCAATTTGTTTATTCAACAA
AGGGAATTGGTAACAAAACAGAAATAAGTGTCAGGGGGCAAGACAGGCTTATAATTTCTACACCAAACCAGAGAAATGAAAAGCCAACGC
AGAGTGTATCATCTCCTGAAGCAACATCTGGTTCTACAGGCTCAGTAGAAAAGAAGCAACAGAGAAGATCAATTAGAACTCGTTCTGAAT
CAGAGAAATCCACTGAGGTTGTGCCAAAGAAGAAGATCAAAAAGGAGCAGGTTGAAACAGTTCCTCAGGCTACAGTGAAGACTGGATTAC
AGAAAGGTGCCAGCGAGATTTCAGATTCCTGTAAACCTCTAAAGAAAAGGAGTCGCGCCTCAACTGATGTAGAAATGACTAGTTCAGCAT
ACAGAGACACATCTGACTCCGATTCTAGAGGACTGAGTGACCTGCAGGTAGGCTTTGGAAAGCAAGTAGATAGCCCTTCAGCTACTGCAG
ATGCAGACGTTTCTGATGTGCAGTCCATGGATTCAAGTTTGTCGAGAAGAGGCACTGGAATGAGTAAGAAGGACACTGTATGTCAGATTT
GTGAAAGCTCTGGTGACTCTCTGATTCCTTGTGAGGGAGAGTGCTGCAAACACTTTCACCTGGAGTGCCTGGGATTGGCATCACTTCCTG
ATAGCAAGTTCATCTGCATGGAATGTAAAACTGGGCAGCACCCATGTTTTTCGTGTAAAGTGTCTGGTAAAGATGTGAAGCGTTGTTCTG
TTGGTGCTTGTGGGAAATTTTATCATGAAGCCTGTGTCCGCAAATTCCCCACTGCCATCTTTGAATCAAAAGGATTCCGCTGTCCTCAGC
ACTGCTGCTCTGCCTGCTCTATGGAGAAAGATATCCACAAAGCAAGTAAAGGCCGCATGATGAGATGTTTAAGATGTCCAGTTGCCTATC
ACTCTGGAGATGCTTGCATTGCGGCCGGAAGCATGTTAGTATCCTCCTACATTCTCATCTGTAGTAATCATTCCAAACGGAGCAGTAATT
CTTCTGCTGTAAATGTAGGCTTTTGTTTCGTTTGTGCCAGAGGTGGAAGATTGCTCTGCTGTGAATCGTGCCCAGCTTCCTTCCACCCGG
AATGCCTAAGCATAGAAATGCCAGAAGGCTGCTGGAATTGTAATGACTGTAAAGCTGGCAAGAAACTACATTACAAGCAGATTGTTTGGG
TCAAATTGGGAAATTACAGATGGTGGCCAGCAGAGATCTGCAACCCCAGGTCTGTGCCACTGAACATCCAGGGCCTTAAACATGACTTGG
GGGACTTCCCTGTATTCTTCTTTGGTTCTCATGACTACTACTGGGTACACCAGGGCAGAGTGTTCCCTTATGTTGAAGGAGACAAAAGCT
TTGCTGAAGGGCAGACTAGTATTAACAAGACCTTCAAAAAGGCACTGGAAGAAGCTGCAAAACGTTTCCAGGAATTGAAAGCACAAAGAG
AAAGTAAAGAAGCCCTAGAGATTGAAAAAAACTCAAGAAAACCCCCTCCCTACAAACACATCAAAGCTAACAAAGTAATAGGAAAGGTGC
AGATCCAGGTTGCTGACCTGTCAGAGATTCCCCGCTGTAACTGCAAGCCAGCTGATGAAAACCCTTGTGGCTTGGAATCGGAGTGCCTGA
ACAGAATGTTGCAGTATGAATGCCACCCGCAGGTGTGCCCAGCTGGAGATCGTTGTCAGAACCAGTGCTTTACAAAGAGACTATACCCTG
ATGCAGAGATCATCAAAACGGAGCGGAGAGGCTGGGGCCTCAGGACCAAAAGGAGCATTAAGAAGGGTGAATTTGTAAATGAATACGTCG
GTGAATTAATTGATGAAGAAGAATGCAGATTGCGAATCAAGCGAGCCCACGAGAACAGTGTAACTAATTTTTATATGTTAACTGTTACCA
AGGACCGTATAATTGATGCCGGCCCAAAAGGAAATTATTCTCGCTTCATGAACCACAGTTGTAATCCCAACTGTGAAACACAAAAGTGGA
CAGTGAATGGAGATGTTCGAGTGGGACTATTTGCTCTCTGTGATATTCCTGCAGTAATTCATCCGTTGTATCAGAAAGCGATGACGTGGG
ACATTAATATTGCACAGAACTTCCATAGCAAATAACCTAAAGGAACGAATGTGCTTTATTTATAACCTTACGTTATCCCCAATGCATTGT

>99193_99193_2_WHSC1L1-ADAM18_WHSC1L1_chr8_38137057_ENST00000433384_ADAM18_chr8_39587416_ENST00000265707_length(amino acids)=1227AA_BP=1204
MDFSFSFMQGIMGNTIQQPPQLIDSANIRQEDAFDNNSDIAEDGGQTPYEATLQQGFQYPATTEDLPPLTNGYPSSISVYETQTKYQSYN
QYPNGSANGFGAVRNFSPTDYYHSEIPNTRPHEILEKPSPPQPPPPPSVPQTVIPKKTGSPEIKLKITKTIQNGRELFESSLCGDLLNEV
QASEHTKSKHESRKEKRKKSNKHDSSRSEERKSHKIPKLEPEEQNRPNERVDTVSEKPREEPVLKEEAPVQPILSSVPTTEVSTGVKFQV
GDLVWSKVGTYPWWPCMVSSDPQLEVHTKINTRGAREYHVQFFSNQPERAWVHEKRVREYKGHKQYEELLAEATKQASNHSEKQKIRKPR
PQRERAQWDIGIAHAEKALKMTREERIEQYTFIYIDKQPEEALSQAKKSVASKTEVKKTRRPRSVLNTQPEQTNAGEVASSLSSTEIRRH
SQRRHTSAEEEEPPPVKIAWKTAAARKSLPASITMHKGSLDLQKCNMSPVVKIEQVFALQNATGDGKFIDQFVYSTKGIGNKTEISVRGQ
DRLIISTPNQRNEKPTQSVSSPEATSGSTGSVEKKQQRRSIRTRSESEKSTEVVPKKKIKKEQVETVPQATVKTGLQKGASEISDSCKPL
KKRSRASTDVEMTSSAYRDTSDSDSRGLSDLQVGFGKQVDSPSATADADVSDVQSMDSSLSRRGTGMSKKDTVCQICESSGDSLIPCEGE
CCKHFHLECLGLASLPDSKFICMECKTGQHPCFSCKVSGKDVKRCSVGACGKFYHEACVRKFPTAIFESKGFRCPQHCCSACSMEKDIHK
ASKGRMMRCLRCPVAYHSGDACIAAGSMLVSSYILICSNHSKRSSNSSAVNVGFCFVCARGGRLLCCESCPASFHPECLSIEMPEGCWNC
NDCKAGKKLHYKQIVWVKLGNYRWWPAEICNPRSVPLNIQGLKHDLGDFPVFFFGSHDYYWVHQGRVFPYVEGDKSFAEGQTSINKTFKK
ALEEAAKRFQELKAQRESKEALEIEKNSRKPPPYKHIKANKVIGKVQIQVADLSEIPRCNCKPADENPCGLESECLNRMLQYECHPQVCP
AGDRCQNQCFTKRLYPDAEIIKTERRGWGLRTKRSIKKGEFVNEYVGELIDEEECRLRIKRAHENSVTNFYMLTVTKDRIIDAGPKGNYS

--------------------------------------------------------------
>99193_99193_3_WHSC1L1-ADAM18_WHSC1L1_chr8_38137057_ENST00000527502_ADAM18_chr8_39587416_ENST00000265707_length(transcript)=3985nt_BP=3819nt
TGTGATCGCACTGACACGGCCGGGGGGTTAGAATGGAACAAACTGAAGGCCCGATGAGAGAAAGGGAAAGTTAAGGATGCTGGAGCAGAA
CAATGGATTTCTCTTTCTCTTTCATGCAAGGGATCATGGGAAACACAATTCAGCAACCACCTCAACTCATTGACTCCGCCAACATCCGTC
AGGAGGATGCCTTTGATAACAACAGTGACATTGCTGAAGATGGTGGCCAGACACCATATGAAGCTACTTTGCAGCAAGGCTTTCAGTACC
CAGCTACAACAGAAGATCTTCCTCCACTCACAAATGGGTATCCATCATCAATCAGTGTGTATGAAACTCAAACCAAATACCAGTCATATA
ATCAGTATCCTAATGGGTCAGCCAATGGCTTTGGTGCAGTTAGAAACTTTAGCCCCACTGACTATTATCATTCAGAAATTCCAAACACAA
GACCACATGAAATTCTGGAAAAACCTTCCCCTCCACAGCCACCACCTCCTCCTTCGGTACCACAAACTGTGATTCCAAAGAAGACTGGCT
CACCTGAAATTAAACTAAAAATAACCAAAACTATCCAGAATGGCAGGGAATTGTTTGAGTCTTCCCTTTGTGGAGACCTTTTAAATGAAG
TACAGGCAAGTGAGCACACGAAATCAAAGCATGAAAGCAGAAAAGAAAAGAGGAAAAAAAGCAACAAGCATGACTCATCAAGATCTGAAG
AGCGCAAGTCACACAAAATCCCCAAATTAGAACCAGAGGAACAAAATAGACCAAATGAGAGGGTTGACACTGTATCAGAAAAACCAAGGG
AAGAACCAGTACTAAAAGAGGAAGCCCCAGTTCAGCCAATACTATCTTCTGTTCCAACAACGGAAGTGTCCACTGGTGTTAAGTTTCAGG
TTGGCGATCTTGTGTGGTCCAAGGTGGGAACCTATCCTTGGTGGCCTTGTATGGTTTCAAGTGATCCCCAGCTTGAGGTTCATACTAAAA
TTAACACAAGAGGTGCCCGAGAATATCATGTCCAGTTTTTTAGCAACCAGCCAGAGAGGGCGTGGGTTCATGAAAAACGGGTACGAGAGT
ATAAAGGTCATAAACAGTATGAAGAATTACTGGCTGAGGCAACCAAACAAGCCAGCAATCACTCTGAGAAACAAAAGATTCGGAAACCCC
GACCTCAGAGAGAACGTGCTCAGTGGGATATTGGCATTGCCCATGCAGAGAAAGCATTGAAAATGACTCGAGAAGAAAGAATAGAACAGT
ATACTTTTATTTACATTGATAAACAGCCTGAAGAGGCTTTATCCCAAGCAAAAAAGAGTGTTGCCTCCAAAACCGAAGTTAAAAAAACCC
GACGACCAAGATCTGTGCTGAATACTCAGCCAGAACAGACCAATGCAGGGGAGGTGGCCTCCTCACTCTCAAGTACTGAAATTCGGAGAC
ATAGCCAGAGGCGGCACACAAGTGCGGAAGAGGAAGAGCCACCGCCTGTTAAAATAGCCTGGAAAACTGCGGCAGCAAGGAAATCCTTAC
CAGCTTCCATTACGATGCACAAAGGGAGCCTGGATTTGCAGAAGTGTAACATGTCTCCAGTTGTGAAAATTGAACAAGTGTTTGCTCTTC
AGAATGCTACAGGGGATGGGAAATTTATCGATCAATTTGTTTATTCAACAAAGGGAATTGGTAACAAAACAGAAATAAGTGTCAGGGGGC
AAGACAGGCTTATAATTTCTACACCAAACCAGAGAAATGAAAAGCCAACGCAGAGTGTATCATCTCCTGAAGCAACATCTGGTTCTACAG
GCTCAGTAGAAAAGAAGCAACAGAGAAGATCAATTAGAACTCGTTCTGAATCAGAGAAATCCACTGAGGTTGTGCCAAAGAAGAAGATCA
AAAAGGAGCAGGTTGAAACAGTTCCTCAGGCTACAGTGAAGACTGGATTACAGAAAGGTGCCAGCGAGATTTCAGATTCCTGTAAACCTC
TAAAGAAAAGGAGTCGCGCCTCAACTGATGTAGAAATGACTAGTTCAGCATACAGAGACACATCTGACTCCGATTCTAGAGGACTGAGTG
ACCTGCAGGTAGGCTTTGGAAAGCAAGTAGATAGCCCTTCAGCTACTGCAGATGCAGACGTTTCTGATGTGCAGTCCATGGATTCAAGTT
TGTCGAGAAGAGGCACTGGAATGAGTAAGAAGGACACTGTATGTCAGATTTGTGAAAGCTCTGGTGACTCTCTGATTCCTTGTGAGGGAG
AGTGCTGCAAACACTTTCACCTGGAGTGCCTGGGATTGGCATCACTTCCTGATAGCAAGTTCATCTGCATGGAATGTAAAACTGGGCAGC
ACCCATGTTTTTCGTGTAAAGTGTCTGGTAAAGATGTGAAGCGTTGTTCTGTTGGTGCTTGTGGGAAATTTTATCATGAAGCCTGTGTCC
GCAAATTCCCCACTGCCATCTTTGAATCAAAAGGATTCCGCTGTCCTCAGCACTGCTGCTCTGCCTGCTCTATGGAGAAAGATATCCACA
AAGCAAGTAAAGGCCGCATGATGAGATGTTTAAGATGTCCAGTTGCCTATCACTCTGGAGATGCTTGCATTGCGGCCGGAAGCATGTTAG
TATCCTCCTACATTCTCATCTGTAGTAATCATTCCAAACGGAGCAGTAATTCTTCTGCTGTAAATGTAGGCTTTTGTTTCGTTTGTGCCA
GAGGGCTGATAGTTCAGGACCATTCAGACCCCATGTTCAGTTCATATGCCTATAAGTCCCACTACCTACTGAATGAATCAAATCGTGCTG
AGTTGATGAAATTACCTATGATTCCTTCTTCGTCAGCTTCCAAAAAGAAATGTGAGAAAGGTGGAAGATTGCTCTGCTGTGAATCGTGCC
CAGCTTCCTTCCACCCGGAATGCCTAAGCATAGAAATGCCAGAAGGCTGCTGGAATTGTAATGACTGTAAAGCTGGCAAGAAACTACATT
ACAAGCAGATTGTTTGGGTCAAATTGGGAAATTACAGATGGTGGCCAGCAGAGATCTGCAACCCCAGGTCTGTGCCACTGAACATCCAGG
GCCTTAAACATGACTTGGGGGACTTCCCTGTATTCTTCTTTGGTTCTCATGACTACTACTGGGTACACCAGGGCAGAGTGTTCCCTTATG
TTGAAGGAGACAAAAGCTTTGCTGAAGGGCAGACTAGTATTAACAAGACCTTCAAAAAGGCACTGGAAGAAGCTGCAAAACGTTTCCAGG
AATTGAAAGCACAAAGAGAAAGTAAAGAAGCCCTAGAGATTGAAAAAAACTCAAGAAAACCCCCTCCCTACAAACACATCAAAGCTAACA
AAGTAATAGGAAAGGTGCAGATCCAGGTTGCTGACCTGTCAGAGATTCCCCGCTGTAACTGCAAGCCAGCTGATGAAAACCCTTGTGGCT
TGGAATCGGAGTGCCTGAACAGAATGTTGCAGTATGAATGCCACCCGCAGGTGTGCCCAGCTGGAGATCGTTGTCAGAACCAGTGCTTTA
CAAAGAGACTATACCCTGATGCAGAGATCATCAAAACGGAGCGGAGAGGCTGGGGCCTCAGGACCAAAAGGAGCATTAAGAAGGGTGAAT
TTGTAAATGAATACGTCGGTGAATTAATTGATGAAGAAGAATGCAGATTGCGAATCAAGCGAGCCCACGAGAACAGTGACCGTATAATTG
ATGCCGGCCCAAAAGGAAATTATTCTCGCTTCATGAACCACAGTTGTAATCCCAACTGTGAAACACAAAAGTGGACAGTGAATGGAGATG
TTCGAGTGGGACTATTTGCTCTCTGTGATATTCCTGCAGTAATTCATCCGTTGTATCAGAAAGCGATGACGTGGGACATTAATATTGCAC
AGAACTTCCATAGCAAATAACCTAAAGGAACGAATGTGCTTTATTTATAACCTTACGTTATCCCCAATGCATTGTAAATGTCAAACTTTT

>99193_99193_3_WHSC1L1-ADAM18_WHSC1L1_chr8_38137057_ENST00000527502_ADAM18_chr8_39587416_ENST00000265707_length(amino acids)=1265AA_BP=1242
MDFSFSFMQGIMGNTIQQPPQLIDSANIRQEDAFDNNSDIAEDGGQTPYEATLQQGFQYPATTEDLPPLTNGYPSSISVYETQTKYQSYN
QYPNGSANGFGAVRNFSPTDYYHSEIPNTRPHEILEKPSPPQPPPPPSVPQTVIPKKTGSPEIKLKITKTIQNGRELFESSLCGDLLNEV
QASEHTKSKHESRKEKRKKSNKHDSSRSEERKSHKIPKLEPEEQNRPNERVDTVSEKPREEPVLKEEAPVQPILSSVPTTEVSTGVKFQV
GDLVWSKVGTYPWWPCMVSSDPQLEVHTKINTRGAREYHVQFFSNQPERAWVHEKRVREYKGHKQYEELLAEATKQASNHSEKQKIRKPR
PQRERAQWDIGIAHAEKALKMTREERIEQYTFIYIDKQPEEALSQAKKSVASKTEVKKTRRPRSVLNTQPEQTNAGEVASSLSSTEIRRH
SQRRHTSAEEEEPPPVKIAWKTAAARKSLPASITMHKGSLDLQKCNMSPVVKIEQVFALQNATGDGKFIDQFVYSTKGIGNKTEISVRGQ
DRLIISTPNQRNEKPTQSVSSPEATSGSTGSVEKKQQRRSIRTRSESEKSTEVVPKKKIKKEQVETVPQATVKTGLQKGASEISDSCKPL
KKRSRASTDVEMTSSAYRDTSDSDSRGLSDLQVGFGKQVDSPSATADADVSDVQSMDSSLSRRGTGMSKKDTVCQICESSGDSLIPCEGE
CCKHFHLECLGLASLPDSKFICMECKTGQHPCFSCKVSGKDVKRCSVGACGKFYHEACVRKFPTAIFESKGFRCPQHCCSACSMEKDIHK
ASKGRMMRCLRCPVAYHSGDACIAAGSMLVSSYILICSNHSKRSSNSSAVNVGFCFVCARGLIVQDHSDPMFSSYAYKSHYLLNESNRAE
LMKLPMIPSSSASKKKCEKGGRLLCCESCPASFHPECLSIEMPEGCWNCNDCKAGKKLHYKQIVWVKLGNYRWWPAEICNPRSVPLNIQG
LKHDLGDFPVFFFGSHDYYWVHQGRVFPYVEGDKSFAEGQTSINKTFKKALEEAAKRFQELKAQRESKEALEIEKNSRKPPPYKHIKANK
VIGKVQIQVADLSEIPRCNCKPADENPCGLESECLNRMLQYECHPQVCPAGDRCQNQCFTKRLYPDAEIIKTERRGWGLRTKRSIKKGEF
VNEYVGELIDEEECRLRIKRAHENSDRIIDAGPKGNYSRFMNHSCNPNCETQKWTVNGDVRVGLFALCDIPAVIHPLYQKAMTWDINIAQ

--------------------------------------------------------------
>99193_99193_4_WHSC1L1-ADAM18_WHSC1L1_chr8_38137058_ENST00000317025_ADAM18_chr8_39587417_ENST00000265707_length(transcript)=4444nt_BP=4278nt
GGGGGCTTTGTGCGCGGCGGCGGCGGGAGAGGCGGCGGCGGCGGCCAGCACGGAGGCGGAGGCCGAGGGGGCTGTGCACAGGTCGCCGCG
GAGAGGCGTGCGAATTCCGAGCCGAGCGCCGAGGACCGTGCTACCCAGGCCGGGCTGCCAGCCGCAGGCTCCTCTCTGGCAGCAGCGGCG
GCGCGGCGACCCCCGTCCCTCGGCCTCCCCTTCCCATCCCACCTCCCGAGCCTTCCTCTTCCCGCAGCACGCCCGGCCCGGCCCGGCCGT
GGCCCTCCTCAGTGCCGGCCGCCATGGCAGAGGCGTCCGGCGCGGGGAAAATCTAGCCCGGGGATTTCATGCGGCCTAGCTCGGTTCCGC
CTCCTCCTCGCGCGGCCCCAGCGGCTGCCCGCACCCCAGCCCCACTCCGGGCCTCCGTGTCTCTCCTGTGATCGCACTGACACGGCCGGG
GGGTTAGAATGGAACAAACTGAAGGCCCGATGAGAGAAAGGGAAAGTTAAGGATGCTGGAGCAGAACAATGGATTTCTCTTTCTCTTTCA
TGCAAGGGATCATGGGAAACACAATTCAGCAACCACCTCAACTCATTGACTCCGCCAACATCCGTCAGGAGGATGCCTTTGATAACAACA
GTGACATTGCTGAAGATGGTGGCCAGACACCATATGAAGCTACTTTGCAGCAAGGCTTTCAGTACCCAGCTACAACAGAAGATCTTCCTC
CACTCACAAATGGGTATCCATCATCAATCAGTGTGTATGAAACTCAAACCAAATACCAGTCATATAATCAGTATCCTAATGGGTCAGCCA
ATGGCTTTGGTGCAGTTAGAAACTTTAGCCCCACTGACTATTATCATTCAGAAATTCCAAACACAAGACCACATGAAATTCTGGAAAAAC
CTTCCCCTCCACAGCCACCACCTCCTCCTTCGGTACCACAAACTGTGATTCCAAAGAAGACTGGCTCACCTGAAATTAAACTAAAAATAA
CCAAAACTATCCAGAATGGCAGGGAATTGTTTGAGTCTTCCCTTTGTGGAGACCTTTTAAATGAAGTACAGGCAAGTGAGCACACGAAAT
CAAAGCATGAAAGCAGAAAAGAAAAGAGGAAAAAAAGCAACAAGCATGACTCATCAAGATCTGAAGAGCGCAAGTCACACAAAATCCCCA
AATTAGAACCAGAGGAACAAAATAGACCAAATGAGAGGGTTGACACTGTATCAGAAAAACCAAGGGAAGAACCAGTACTAAAAGAGGAAG
CCCCAGTTCAGCCAATACTATCTTCTGTTCCAACAACGGAAGTGTCCACTGGTGTTAAGTTTCAGGTTGGCGATCTTGTGTGGTCCAAGG
TGGGAACCTATCCTTGGTGGCCTTGTATGGTTTCAAGTGATCCCCAGCTTGAGGTTCATACTAAAATTAACACAAGAGGTGCCCGAGAAT
ATCATGTCCAGTTTTTTAGCAACCAGCCAGAGAGGGCGTGGGTTCATGAAAAACGGGTACGAGAGTATAAAGGTCATAAACAGTATGAAG
AATTACTGGCTGAGGCAACCAAACAAGCCAGCAATCACTCTGAGAAACAAAAGATTCGGAAACCCCGACCTCAGAGAGAACGTGCTCAGT
GGGATATTGGCATTGCCCATGCAGAGAAAGCATTGAAAATGACTCGAGAAGAAAGAATAGAACAGTATACTTTTATTTACATTGATAAAC
AGCCTGAAGAGGCTTTATCCCAAGCAAAAAAGAGTGTTGCCTCCAAAACCGAAGTTAAAAAAACCCGACGACCAAGATCTGTGCTGAATA
CTCAGCCAGAACAGACCAATGCAGGGGAGGTGGCCTCCTCACTCTCAAGTACTGAAATTCGGAGACATAGCCAGAGGCGGCACACAAGTG
CGGAAGAGGAAGAGCCACCGCCTGTTAAAATAGCCTGGAAAACTGCGGCAGCAAGGAAATCCTTACCAGCTTCCATTACGATGCACAAAG
GGAGCCTGGATTTGCAGAAGTGTAACATGTCTCCAGTTGTGAAAATTGAACAAGTGTTTGCTCTTCAGAATGCTACAGGGGATGGGAAAT
TTATCGATCAATTTGTTTATTCAACAAAGGGAATTGGTAACAAAACAGAAATAAGTGTCAGGGGGCAAGACAGGCTTATAATTTCTACAC
CAAACCAGAGAAATGAAAAGCCAACGCAGAGTGTATCATCTCCTGAAGCAACATCTGGTTCTACAGGCTCAGTAGAAAAGAAGCAACAGA
GAAGATCAATTAGAACTCGTTCTGAATCAGAGAAATCCACTGAGGTTGTGCCAAAGAAGAAGATCAAAAAGGAGCAGGTTGAAACAGTTC
CTCAGGCTACAGTGAAGACTGGATTACAGAAAGGTGCCAGCGAGATTTCAGATTCCTGTAAACCTCTAAAGAAAAGGAGTCGCGCCTCAA
CTGATGTAGAAATGACTAGTTCAGCATACAGAGACACATCTGACTCCGATTCTAGAGGACTGAGTGACCTGCAGGTAGGCTTTGGAAAGC
AAGTAGATAGCCCTTCAGCTACTGCAGATGCAGACGTTTCTGATGTGCAGTCCATGGATTCAAGTTTGTCGAGAAGAGGCACTGGAATGA
GTAAGAAGGACACTGTATGTCAGATTTGTGAAAGCTCTGGTGACTCTCTGATTCCTTGTGAGGGAGAGTGCTGCAAACACTTTCACCTGG
AGTGCCTGGGATTGGCATCACTTCCTGATAGCAAGTTCATCTGCATGGAATGTAAAACTGGGCAGCACCCATGTTTTTCGTGTAAAGTGT
CTGGTAAAGATGTGAAGCGTTGTTCTGTTGGTGCTTGTGGGAAATTTTATCATGAAGCCTGTGTCCGCAAATTCCCCACTGCCATCTTTG
AATCAAAAGGATTCCGCTGTCCTCAGCACTGCTGCTCTGCCTGCTCTATGGAGAAAGATATCCACAAAGCAAGTAAAGGCCGCATGATGA
GATGTTTAAGATGTCCAGTTGCCTATCACTCTGGAGATGCTTGCATTGCGGCCGGAAGCATGTTAGTATCCTCCTACATTCTCATCTGTA
GTAATCATTCCAAACGGAGCAGTAATTCTTCTGCTGTAAATGTAGGCTTTTGTTTCGTTTGTGCCAGAGGGCTGATAGTTCAGGACCATT
CAGACCCCATGTTCAGTTCATATGCCTATAAGTCCCACTACCTACTGAATGAATCAAATCGTGCTGAGTTGATGAAATTACCTATGATTC
CTTCTTCGTCAGCTTCCAAAAAGAAATGTGAGAAAGGTGGAAGATTGCTCTGCTGTGAATCGTGCCCAGCTTCCTTCCACCCGGAATGCC
TAAGCATAGAAATGCCAGAAGGCTGCTGGAATTGTAATGACTGTAAAGCTGGCAAGAAACTACATTACAAGCAGATTGTTTGGGTCAAAT
TGGGAAATTACAGATGGTGGCCAGCAGAGATCTGCAACCCCAGGTCTGTGCCACTGAACATCCAGGGCCTTAAACATGACTTGGGGGACT
TCCCTGTATTCTTCTTTGGTTCTCATGACTACTACTGGGTACACCAGGGCAGAGTGTTCCCTTATGTTGAAGGAGACAAAAGCTTTGCTG
AAGGGCAGACTAGTATTAACAAGACCTTCAAAAAGGCACTGGAAGAAGCTGCAAAACGTTTCCAGGAATTGAAAGCACAAAGAGAAAGTA
AAGAAGCCCTAGAGATTGAAAAAAACTCAAGAAAACCCCCTCCCTACAAACACATCAAAGCTAACAAAGTAATAGGAAAGGTGCAGATCC
AGGTTGCTGACCTGTCAGAGATTCCCCGCTGTAACTGCAAGCCAGCTGATGAAAACCCTTGTGGCTTGGAATCGGAGTGCCTGAACAGAA
TGTTGCAGTATGAATGCCACCCGCAGGTGTGCCCAGCTGGAGATCGTTGTCAGAACCAGTGCTTTACAAAGAGACTATACCCTGATGCAG
AGATCATCAAAACGGAGCGGAGAGGCTGGGGCCTCAGGACCAAAAGGAGCATTAAGAAGGGTGAATTTGTAAATGAATACGTCGGTGAAT
TAATTGATGAAGAAGAATGCAGATTGCGAATCAAGCGAGCCCACGAGAACAGTGTAACTAATTTTTATATGTTAACTGTTACCAAGGACC
GTATAATTGATGCCGGCCCAAAAGGAAATTATTCTCGCTTCATGAACCACAGTTGTAATCCCAACTGTGAAACACAAAAGTGGACAGTGA
ATGGAGATGTTCGAGTGGGACTATTTGCTCTCTGTGATATTCCTGCAGTAATTCATCCGTTGTATCAGAAAGCGATGACGTGGGACATTA
ATATTGCACAGAACTTCCATAGCAAATAACCTAAAGGAACGAATGTGCTTTATTTATAACCTTACGTTATCCCCAATGCATTGTAAATGT

>99193_99193_4_WHSC1L1-ADAM18_WHSC1L1_chr8_38137058_ENST00000317025_ADAM18_chr8_39587417_ENST00000265707_length(amino acids)=1276AA_BP=1253
MDFSFSFMQGIMGNTIQQPPQLIDSANIRQEDAFDNNSDIAEDGGQTPYEATLQQGFQYPATTEDLPPLTNGYPSSISVYETQTKYQSYN
QYPNGSANGFGAVRNFSPTDYYHSEIPNTRPHEILEKPSPPQPPPPPSVPQTVIPKKTGSPEIKLKITKTIQNGRELFESSLCGDLLNEV
QASEHTKSKHESRKEKRKKSNKHDSSRSEERKSHKIPKLEPEEQNRPNERVDTVSEKPREEPVLKEEAPVQPILSSVPTTEVSTGVKFQV
GDLVWSKVGTYPWWPCMVSSDPQLEVHTKINTRGAREYHVQFFSNQPERAWVHEKRVREYKGHKQYEELLAEATKQASNHSEKQKIRKPR
PQRERAQWDIGIAHAEKALKMTREERIEQYTFIYIDKQPEEALSQAKKSVASKTEVKKTRRPRSVLNTQPEQTNAGEVASSLSSTEIRRH
SQRRHTSAEEEEPPPVKIAWKTAAARKSLPASITMHKGSLDLQKCNMSPVVKIEQVFALQNATGDGKFIDQFVYSTKGIGNKTEISVRGQ
DRLIISTPNQRNEKPTQSVSSPEATSGSTGSVEKKQQRRSIRTRSESEKSTEVVPKKKIKKEQVETVPQATVKTGLQKGASEISDSCKPL
KKRSRASTDVEMTSSAYRDTSDSDSRGLSDLQVGFGKQVDSPSATADADVSDVQSMDSSLSRRGTGMSKKDTVCQICESSGDSLIPCEGE
CCKHFHLECLGLASLPDSKFICMECKTGQHPCFSCKVSGKDVKRCSVGACGKFYHEACVRKFPTAIFESKGFRCPQHCCSACSMEKDIHK
ASKGRMMRCLRCPVAYHSGDACIAAGSMLVSSYILICSNHSKRSSNSSAVNVGFCFVCARGLIVQDHSDPMFSSYAYKSHYLLNESNRAE
LMKLPMIPSSSASKKKCEKGGRLLCCESCPASFHPECLSIEMPEGCWNCNDCKAGKKLHYKQIVWVKLGNYRWWPAEICNPRSVPLNIQG
LKHDLGDFPVFFFGSHDYYWVHQGRVFPYVEGDKSFAEGQTSINKTFKKALEEAAKRFQELKAQRESKEALEIEKNSRKPPPYKHIKANK
VIGKVQIQVADLSEIPRCNCKPADENPCGLESECLNRMLQYECHPQVCPAGDRCQNQCFTKRLYPDAEIIKTERRGWGLRTKRSIKKGEF
VNEYVGELIDEEECRLRIKRAHENSVTNFYMLTVTKDRIIDAGPKGNYSRFMNHSCNPNCETQKWTVNGDVRVGLFALCDIPAVIHPLYQ

--------------------------------------------------------------
>99193_99193_5_WHSC1L1-ADAM18_WHSC1L1_chr8_38137058_ENST00000433384_ADAM18_chr8_39587417_ENST00000265707_length(transcript)=4270nt_BP=4104nt
AGAGGCGGCGGCGGCGGCCAGCACGGAGGCGGAGGCCGAGGGGGCTGTGCACAGGTCGCCGCGGAGAGGCGTGCGAATTCCGAGCCGAGC
GCCGAGGACCGTGCTACCCAGGCCGGGCTGCCAGCCGCAGGCTCCTCTCTGGCAGCAGCGGCGGCGCGGCGACCCCCGTCCCTCGGCCTC
CCCTTCCCATCCCACCTCCCGAGCCTTCCTCTTCCCGCAGCACGCCCGGCCCGGCCCGGCCGTGGCCCTCCTCAGTGCCGGCCGCCATGG
CAGAGGCGTCCGGCGCGGGGAAAATCTAGCCCGGGGATTTCATGCGGCCTAGCTCGGTTCCGCCTCCTCCTCGCGCGGCCCCAGCGGCTG
CCCGCACCCCAGCCCCACTCCGGGCCTCCGTGTCTCTCCTGTGATCGCACTGACACGGCCGGGGGGTTAGAATGGAACAAACTGAAGGCC
CGATGAGAGAAAGGGAAAGTTAAGGATGCTGGAGCAGAACAATGGATTTCTCTTTCTCTTTCATGCAAGGGATCATGGGAAACACAATTC
AGCAACCACCTCAACTCATTGACTCCGCCAACATCCGTCAGGAGGATGCCTTTGATAACAACAGTGACATTGCTGAAGATGGTGGCCAGA
CACCATATGAAGCTACTTTGCAGCAAGGCTTTCAGTACCCAGCTACAACAGAAGATCTTCCTCCACTCACAAATGGGTATCCATCATCAA
TCAGTGTGTATGAAACTCAAACCAAATACCAGTCATATAATCAGTATCCTAATGGGTCAGCCAATGGCTTTGGTGCAGTTAGAAACTTTA
GCCCCACTGACTATTATCATTCAGAAATTCCAAACACAAGACCACATGAAATTCTGGAAAAACCTTCCCCTCCACAGCCACCACCTCCTC
CTTCGGTACCACAAACTGTGATTCCAAAGAAGACTGGCTCACCTGAAATTAAACTAAAAATAACCAAAACTATCCAGAATGGCAGGGAAT
TGTTTGAGTCTTCCCTTTGTGGAGACCTTTTAAATGAAGTACAGGCAAGTGAGCACACGAAATCAAAGCATGAAAGCAGAAAAGAAAAGA
GGAAAAAAAGCAACAAGCATGACTCATCAAGATCTGAAGAGCGCAAGTCACACAAAATCCCCAAATTAGAACCAGAGGAACAAAATAGAC
CAAATGAGAGGGTTGACACTGTATCAGAAAAACCAAGGGAAGAACCAGTACTAAAAGAGGAAGCCCCAGTTCAGCCAATACTATCTTCTG
TTCCAACAACGGAAGTGTCCACTGGTGTTAAGTTTCAGGTTGGCGATCTTGTGTGGTCCAAGGTGGGAACCTATCCTTGGTGGCCTTGTA
TGGTTTCAAGTGATCCCCAGCTTGAGGTTCATACTAAAATTAACACAAGAGGTGCCCGAGAATATCATGTCCAGTTTTTTAGCAACCAGC
CAGAGAGGGCGTGGGTTCATGAAAAACGGGTACGAGAGTATAAAGGTCATAAACAGTATGAAGAATTACTGGCTGAGGCAACCAAACAAG
CCAGCAATCACTCTGAGAAACAAAAGATTCGGAAACCCCGACCTCAGAGAGAACGTGCTCAGTGGGATATTGGCATTGCCCATGCAGAGA
AAGCATTGAAAATGACTCGAGAAGAAAGAATAGAACAGTATACTTTTATTTACATTGATAAACAGCCTGAAGAGGCTTTATCCCAAGCAA
AAAAGAGTGTTGCCTCCAAAACCGAAGTTAAAAAAACCCGACGACCAAGATCTGTGCTGAATACTCAGCCAGAACAGACCAATGCAGGGG
AGGTGGCCTCCTCACTCTCAAGTACTGAAATTCGGAGACATAGCCAGAGGCGGCACACAAGTGCGGAAGAGGAAGAGCCACCGCCTGTTA
AAATAGCCTGGAAAACTGCGGCAGCAAGGAAATCCTTACCAGCTTCCATTACGATGCACAAAGGGAGCCTGGATTTGCAGAAGTGTAACA
TGTCTCCAGTTGTGAAAATTGAACAAGTGTTTGCTCTTCAGAATGCTACAGGGGATGGGAAATTTATCGATCAATTTGTTTATTCAACAA
AGGGAATTGGTAACAAAACAGAAATAAGTGTCAGGGGGCAAGACAGGCTTATAATTTCTACACCAAACCAGAGAAATGAAAAGCCAACGC
AGAGTGTATCATCTCCTGAAGCAACATCTGGTTCTACAGGCTCAGTAGAAAAGAAGCAACAGAGAAGATCAATTAGAACTCGTTCTGAAT
CAGAGAAATCCACTGAGGTTGTGCCAAAGAAGAAGATCAAAAAGGAGCAGGTTGAAACAGTTCCTCAGGCTACAGTGAAGACTGGATTAC
AGAAAGGTGCCAGCGAGATTTCAGATTCCTGTAAACCTCTAAAGAAAAGGAGTCGCGCCTCAACTGATGTAGAAATGACTAGTTCAGCAT
ACAGAGACACATCTGACTCCGATTCTAGAGGACTGAGTGACCTGCAGGTAGGCTTTGGAAAGCAAGTAGATAGCCCTTCAGCTACTGCAG
ATGCAGACGTTTCTGATGTGCAGTCCATGGATTCAAGTTTGTCGAGAAGAGGCACTGGAATGAGTAAGAAGGACACTGTATGTCAGATTT
GTGAAAGCTCTGGTGACTCTCTGATTCCTTGTGAGGGAGAGTGCTGCAAACACTTTCACCTGGAGTGCCTGGGATTGGCATCACTTCCTG
ATAGCAAGTTCATCTGCATGGAATGTAAAACTGGGCAGCACCCATGTTTTTCGTGTAAAGTGTCTGGTAAAGATGTGAAGCGTTGTTCTG
TTGGTGCTTGTGGGAAATTTTATCATGAAGCCTGTGTCCGCAAATTCCCCACTGCCATCTTTGAATCAAAAGGATTCCGCTGTCCTCAGC
ACTGCTGCTCTGCCTGCTCTATGGAGAAAGATATCCACAAAGCAAGTAAAGGCCGCATGATGAGATGTTTAAGATGTCCAGTTGCCTATC
ACTCTGGAGATGCTTGCATTGCGGCCGGAAGCATGTTAGTATCCTCCTACATTCTCATCTGTAGTAATCATTCCAAACGGAGCAGTAATT
CTTCTGCTGTAAATGTAGGCTTTTGTTTCGTTTGTGCCAGAGGTGGAAGATTGCTCTGCTGTGAATCGTGCCCAGCTTCCTTCCACCCGG
AATGCCTAAGCATAGAAATGCCAGAAGGCTGCTGGAATTGTAATGACTGTAAAGCTGGCAAGAAACTACATTACAAGCAGATTGTTTGGG
TCAAATTGGGAAATTACAGATGGTGGCCAGCAGAGATCTGCAACCCCAGGTCTGTGCCACTGAACATCCAGGGCCTTAAACATGACTTGG
GGGACTTCCCTGTATTCTTCTTTGGTTCTCATGACTACTACTGGGTACACCAGGGCAGAGTGTTCCCTTATGTTGAAGGAGACAAAAGCT
TTGCTGAAGGGCAGACTAGTATTAACAAGACCTTCAAAAAGGCACTGGAAGAAGCTGCAAAACGTTTCCAGGAATTGAAAGCACAAAGAG
AAAGTAAAGAAGCCCTAGAGATTGAAAAAAACTCAAGAAAACCCCCTCCCTACAAACACATCAAAGCTAACAAAGTAATAGGAAAGGTGC
AGATCCAGGTTGCTGACCTGTCAGAGATTCCCCGCTGTAACTGCAAGCCAGCTGATGAAAACCCTTGTGGCTTGGAATCGGAGTGCCTGA
ACAGAATGTTGCAGTATGAATGCCACCCGCAGGTGTGCCCAGCTGGAGATCGTTGTCAGAACCAGTGCTTTACAAAGAGACTATACCCTG
ATGCAGAGATCATCAAAACGGAGCGGAGAGGCTGGGGCCTCAGGACCAAAAGGAGCATTAAGAAGGGTGAATTTGTAAATGAATACGTCG
GTGAATTAATTGATGAAGAAGAATGCAGATTGCGAATCAAGCGAGCCCACGAGAACAGTGTAACTAATTTTTATATGTTAACTGTTACCA
AGGACCGTATAATTGATGCCGGCCCAAAAGGAAATTATTCTCGCTTCATGAACCACAGTTGTAATCCCAACTGTGAAACACAAAAGTGGA
CAGTGAATGGAGATGTTCGAGTGGGACTATTTGCTCTCTGTGATATTCCTGCAGTAATTCATCCGTTGTATCAGAAAGCGATGACGTGGG
ACATTAATATTGCACAGAACTTCCATAGCAAATAACCTAAAGGAACGAATGTGCTTTATTTATAACCTTACGTTATCCCCAATGCATTGT

>99193_99193_5_WHSC1L1-ADAM18_WHSC1L1_chr8_38137058_ENST00000433384_ADAM18_chr8_39587417_ENST00000265707_length(amino acids)=1227AA_BP=1204
MDFSFSFMQGIMGNTIQQPPQLIDSANIRQEDAFDNNSDIAEDGGQTPYEATLQQGFQYPATTEDLPPLTNGYPSSISVYETQTKYQSYN
QYPNGSANGFGAVRNFSPTDYYHSEIPNTRPHEILEKPSPPQPPPPPSVPQTVIPKKTGSPEIKLKITKTIQNGRELFESSLCGDLLNEV
QASEHTKSKHESRKEKRKKSNKHDSSRSEERKSHKIPKLEPEEQNRPNERVDTVSEKPREEPVLKEEAPVQPILSSVPTTEVSTGVKFQV
GDLVWSKVGTYPWWPCMVSSDPQLEVHTKINTRGAREYHVQFFSNQPERAWVHEKRVREYKGHKQYEELLAEATKQASNHSEKQKIRKPR
PQRERAQWDIGIAHAEKALKMTREERIEQYTFIYIDKQPEEALSQAKKSVASKTEVKKTRRPRSVLNTQPEQTNAGEVASSLSSTEIRRH
SQRRHTSAEEEEPPPVKIAWKTAAARKSLPASITMHKGSLDLQKCNMSPVVKIEQVFALQNATGDGKFIDQFVYSTKGIGNKTEISVRGQ
DRLIISTPNQRNEKPTQSVSSPEATSGSTGSVEKKQQRRSIRTRSESEKSTEVVPKKKIKKEQVETVPQATVKTGLQKGASEISDSCKPL
KKRSRASTDVEMTSSAYRDTSDSDSRGLSDLQVGFGKQVDSPSATADADVSDVQSMDSSLSRRGTGMSKKDTVCQICESSGDSLIPCEGE
CCKHFHLECLGLASLPDSKFICMECKTGQHPCFSCKVSGKDVKRCSVGACGKFYHEACVRKFPTAIFESKGFRCPQHCCSACSMEKDIHK
ASKGRMMRCLRCPVAYHSGDACIAAGSMLVSSYILICSNHSKRSSNSSAVNVGFCFVCARGGRLLCCESCPASFHPECLSIEMPEGCWNC
NDCKAGKKLHYKQIVWVKLGNYRWWPAEICNPRSVPLNIQGLKHDLGDFPVFFFGSHDYYWVHQGRVFPYVEGDKSFAEGQTSINKTFKK
ALEEAAKRFQELKAQRESKEALEIEKNSRKPPPYKHIKANKVIGKVQIQVADLSEIPRCNCKPADENPCGLESECLNRMLQYECHPQVCP
AGDRCQNQCFTKRLYPDAEIIKTERRGWGLRTKRSIKKGEFVNEYVGELIDEEECRLRIKRAHENSVTNFYMLTVTKDRIIDAGPKGNYS

--------------------------------------------------------------
>99193_99193_6_WHSC1L1-ADAM18_WHSC1L1_chr8_38137058_ENST00000527502_ADAM18_chr8_39587417_ENST00000265707_length(transcript)=3985nt_BP=3819nt
TGTGATCGCACTGACACGGCCGGGGGGTTAGAATGGAACAAACTGAAGGCCCGATGAGAGAAAGGGAAAGTTAAGGATGCTGGAGCAGAA
CAATGGATTTCTCTTTCTCTTTCATGCAAGGGATCATGGGAAACACAATTCAGCAACCACCTCAACTCATTGACTCCGCCAACATCCGTC
AGGAGGATGCCTTTGATAACAACAGTGACATTGCTGAAGATGGTGGCCAGACACCATATGAAGCTACTTTGCAGCAAGGCTTTCAGTACC
CAGCTACAACAGAAGATCTTCCTCCACTCACAAATGGGTATCCATCATCAATCAGTGTGTATGAAACTCAAACCAAATACCAGTCATATA
ATCAGTATCCTAATGGGTCAGCCAATGGCTTTGGTGCAGTTAGAAACTTTAGCCCCACTGACTATTATCATTCAGAAATTCCAAACACAA
GACCACATGAAATTCTGGAAAAACCTTCCCCTCCACAGCCACCACCTCCTCCTTCGGTACCACAAACTGTGATTCCAAAGAAGACTGGCT
CACCTGAAATTAAACTAAAAATAACCAAAACTATCCAGAATGGCAGGGAATTGTTTGAGTCTTCCCTTTGTGGAGACCTTTTAAATGAAG
TACAGGCAAGTGAGCACACGAAATCAAAGCATGAAAGCAGAAAAGAAAAGAGGAAAAAAAGCAACAAGCATGACTCATCAAGATCTGAAG
AGCGCAAGTCACACAAAATCCCCAAATTAGAACCAGAGGAACAAAATAGACCAAATGAGAGGGTTGACACTGTATCAGAAAAACCAAGGG
AAGAACCAGTACTAAAAGAGGAAGCCCCAGTTCAGCCAATACTATCTTCTGTTCCAACAACGGAAGTGTCCACTGGTGTTAAGTTTCAGG
TTGGCGATCTTGTGTGGTCCAAGGTGGGAACCTATCCTTGGTGGCCTTGTATGGTTTCAAGTGATCCCCAGCTTGAGGTTCATACTAAAA
TTAACACAAGAGGTGCCCGAGAATATCATGTCCAGTTTTTTAGCAACCAGCCAGAGAGGGCGTGGGTTCATGAAAAACGGGTACGAGAGT
ATAAAGGTCATAAACAGTATGAAGAATTACTGGCTGAGGCAACCAAACAAGCCAGCAATCACTCTGAGAAACAAAAGATTCGGAAACCCC
GACCTCAGAGAGAACGTGCTCAGTGGGATATTGGCATTGCCCATGCAGAGAAAGCATTGAAAATGACTCGAGAAGAAAGAATAGAACAGT
ATACTTTTATTTACATTGATAAACAGCCTGAAGAGGCTTTATCCCAAGCAAAAAAGAGTGTTGCCTCCAAAACCGAAGTTAAAAAAACCC
GACGACCAAGATCTGTGCTGAATACTCAGCCAGAACAGACCAATGCAGGGGAGGTGGCCTCCTCACTCTCAAGTACTGAAATTCGGAGAC
ATAGCCAGAGGCGGCACACAAGTGCGGAAGAGGAAGAGCCACCGCCTGTTAAAATAGCCTGGAAAACTGCGGCAGCAAGGAAATCCTTAC
CAGCTTCCATTACGATGCACAAAGGGAGCCTGGATTTGCAGAAGTGTAACATGTCTCCAGTTGTGAAAATTGAACAAGTGTTTGCTCTTC
AGAATGCTACAGGGGATGGGAAATTTATCGATCAATTTGTTTATTCAACAAAGGGAATTGGTAACAAAACAGAAATAAGTGTCAGGGGGC
AAGACAGGCTTATAATTTCTACACCAAACCAGAGAAATGAAAAGCCAACGCAGAGTGTATCATCTCCTGAAGCAACATCTGGTTCTACAG
GCTCAGTAGAAAAGAAGCAACAGAGAAGATCAATTAGAACTCGTTCTGAATCAGAGAAATCCACTGAGGTTGTGCCAAAGAAGAAGATCA
AAAAGGAGCAGGTTGAAACAGTTCCTCAGGCTACAGTGAAGACTGGATTACAGAAAGGTGCCAGCGAGATTTCAGATTCCTGTAAACCTC
TAAAGAAAAGGAGTCGCGCCTCAACTGATGTAGAAATGACTAGTTCAGCATACAGAGACACATCTGACTCCGATTCTAGAGGACTGAGTG
ACCTGCAGGTAGGCTTTGGAAAGCAAGTAGATAGCCCTTCAGCTACTGCAGATGCAGACGTTTCTGATGTGCAGTCCATGGATTCAAGTT
TGTCGAGAAGAGGCACTGGAATGAGTAAGAAGGACACTGTATGTCAGATTTGTGAAAGCTCTGGTGACTCTCTGATTCCTTGTGAGGGAG
AGTGCTGCAAACACTTTCACCTGGAGTGCCTGGGATTGGCATCACTTCCTGATAGCAAGTTCATCTGCATGGAATGTAAAACTGGGCAGC
ACCCATGTTTTTCGTGTAAAGTGTCTGGTAAAGATGTGAAGCGTTGTTCTGTTGGTGCTTGTGGGAAATTTTATCATGAAGCCTGTGTCC
GCAAATTCCCCACTGCCATCTTTGAATCAAAAGGATTCCGCTGTCCTCAGCACTGCTGCTCTGCCTGCTCTATGGAGAAAGATATCCACA
AAGCAAGTAAAGGCCGCATGATGAGATGTTTAAGATGTCCAGTTGCCTATCACTCTGGAGATGCTTGCATTGCGGCCGGAAGCATGTTAG
TATCCTCCTACATTCTCATCTGTAGTAATCATTCCAAACGGAGCAGTAATTCTTCTGCTGTAAATGTAGGCTTTTGTTTCGTTTGTGCCA
GAGGGCTGATAGTTCAGGACCATTCAGACCCCATGTTCAGTTCATATGCCTATAAGTCCCACTACCTACTGAATGAATCAAATCGTGCTG
AGTTGATGAAATTACCTATGATTCCTTCTTCGTCAGCTTCCAAAAAGAAATGTGAGAAAGGTGGAAGATTGCTCTGCTGTGAATCGTGCC
CAGCTTCCTTCCACCCGGAATGCCTAAGCATAGAAATGCCAGAAGGCTGCTGGAATTGTAATGACTGTAAAGCTGGCAAGAAACTACATT
ACAAGCAGATTGTTTGGGTCAAATTGGGAAATTACAGATGGTGGCCAGCAGAGATCTGCAACCCCAGGTCTGTGCCACTGAACATCCAGG
GCCTTAAACATGACTTGGGGGACTTCCCTGTATTCTTCTTTGGTTCTCATGACTACTACTGGGTACACCAGGGCAGAGTGTTCCCTTATG
TTGAAGGAGACAAAAGCTTTGCTGAAGGGCAGACTAGTATTAACAAGACCTTCAAAAAGGCACTGGAAGAAGCTGCAAAACGTTTCCAGG
AATTGAAAGCACAAAGAGAAAGTAAAGAAGCCCTAGAGATTGAAAAAAACTCAAGAAAACCCCCTCCCTACAAACACATCAAAGCTAACA
AAGTAATAGGAAAGGTGCAGATCCAGGTTGCTGACCTGTCAGAGATTCCCCGCTGTAACTGCAAGCCAGCTGATGAAAACCCTTGTGGCT
TGGAATCGGAGTGCCTGAACAGAATGTTGCAGTATGAATGCCACCCGCAGGTGTGCCCAGCTGGAGATCGTTGTCAGAACCAGTGCTTTA
CAAAGAGACTATACCCTGATGCAGAGATCATCAAAACGGAGCGGAGAGGCTGGGGCCTCAGGACCAAAAGGAGCATTAAGAAGGGTGAAT
TTGTAAATGAATACGTCGGTGAATTAATTGATGAAGAAGAATGCAGATTGCGAATCAAGCGAGCCCACGAGAACAGTGACCGTATAATTG
ATGCCGGCCCAAAAGGAAATTATTCTCGCTTCATGAACCACAGTTGTAATCCCAACTGTGAAACACAAAAGTGGACAGTGAATGGAGATG
TTCGAGTGGGACTATTTGCTCTCTGTGATATTCCTGCAGTAATTCATCCGTTGTATCAGAAAGCGATGACGTGGGACATTAATATTGCAC
AGAACTTCCATAGCAAATAACCTAAAGGAACGAATGTGCTTTATTTATAACCTTACGTTATCCCCAATGCATTGTAAATGTCAAACTTTT

>99193_99193_6_WHSC1L1-ADAM18_WHSC1L1_chr8_38137058_ENST00000527502_ADAM18_chr8_39587417_ENST00000265707_length(amino acids)=1265AA_BP=1242
MDFSFSFMQGIMGNTIQQPPQLIDSANIRQEDAFDNNSDIAEDGGQTPYEATLQQGFQYPATTEDLPPLTNGYPSSISVYETQTKYQSYN
QYPNGSANGFGAVRNFSPTDYYHSEIPNTRPHEILEKPSPPQPPPPPSVPQTVIPKKTGSPEIKLKITKTIQNGRELFESSLCGDLLNEV
QASEHTKSKHESRKEKRKKSNKHDSSRSEERKSHKIPKLEPEEQNRPNERVDTVSEKPREEPVLKEEAPVQPILSSVPTTEVSTGVKFQV
GDLVWSKVGTYPWWPCMVSSDPQLEVHTKINTRGAREYHVQFFSNQPERAWVHEKRVREYKGHKQYEELLAEATKQASNHSEKQKIRKPR
PQRERAQWDIGIAHAEKALKMTREERIEQYTFIYIDKQPEEALSQAKKSVASKTEVKKTRRPRSVLNTQPEQTNAGEVASSLSSTEIRRH
SQRRHTSAEEEEPPPVKIAWKTAAARKSLPASITMHKGSLDLQKCNMSPVVKIEQVFALQNATGDGKFIDQFVYSTKGIGNKTEISVRGQ
DRLIISTPNQRNEKPTQSVSSPEATSGSTGSVEKKQQRRSIRTRSESEKSTEVVPKKKIKKEQVETVPQATVKTGLQKGASEISDSCKPL
KKRSRASTDVEMTSSAYRDTSDSDSRGLSDLQVGFGKQVDSPSATADADVSDVQSMDSSLSRRGTGMSKKDTVCQICESSGDSLIPCEGE
CCKHFHLECLGLASLPDSKFICMECKTGQHPCFSCKVSGKDVKRCSVGACGKFYHEACVRKFPTAIFESKGFRCPQHCCSACSMEKDIHK
ASKGRMMRCLRCPVAYHSGDACIAAGSMLVSSYILICSNHSKRSSNSSAVNVGFCFVCARGLIVQDHSDPMFSSYAYKSHYLLNESNRAE
LMKLPMIPSSSASKKKCEKGGRLLCCESCPASFHPECLSIEMPEGCWNCNDCKAGKKLHYKQIVWVKLGNYRWWPAEICNPRSVPLNIQG
LKHDLGDFPVFFFGSHDYYWVHQGRVFPYVEGDKSFAEGQTSINKTFKKALEEAAKRFQELKAQRESKEALEIEKNSRKPPPYKHIKANK
VIGKVQIQVADLSEIPRCNCKPADENPCGLESECLNRMLQYECHPQVCPAGDRCQNQCFTKRLYPDAEIIKTERRGWGLRTKRSIKKGEF
VNEYVGELIDEEECRLRIKRAHENSDRIIDAGPKGNYSRFMNHSCNPNCETQKWTVNGDVRVGLFALCDIPAVIHPLYQKAMTWDINIAQ

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Fusion Gene PPI Analysis for WHSC1L1-ADAM18


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for WHSC1L1-ADAM18


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for WHSC1L1-ADAM18


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource