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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:WHSC1L1-FGFR1 (FusionGDB2 ID:99203)

Fusion Gene Summary for WHSC1L1-FGFR1

check button Fusion gene summary
Fusion gene informationFusion gene name: WHSC1L1-FGFR1
Fusion gene ID: 99203
HgeneTgene
Gene symbol

WHSC1L1

FGFR1

Gene ID

54904

2260

Gene namenuclear receptor binding SET domain protein 3fibroblast growth factor receptor 1
SynonymsKMT3F|KMT3G|WHISTLE|WHSC1L1|pp14328BFGFR|CD331|CEK|ECCL|FGFBR|FGFR-1|FLG|FLT-2|FLT2|HBGFR|HH2|HRTFDS|KAL2|N-SAM|OGD|bFGF-R-1
Cytomap

8p11.23

8p11.23

Type of geneprotein-codingprotein-coding
Descriptionhistone-lysine N-methyltransferase NSD3WHSC1-like 1 isoform 9 with methyltransferase activity to lysineWolf-Hirschhorn syndrome candidate 1-like 1nuclear SET domain-containing protein 3protein whistlefibroblast growth factor receptor 1FGFR1/PLAG1 fusionFMS-like tyrosine kinase 2basic fibroblast growth factor receptor 1fms-related tyrosine kinase 2heparin-binding growth factor receptorhydroxyaryl-protein kinaseproto-oncogene c-Fgr
Modification date2020031320200329
UniProtAcc.

Q9NVK5

Ensembl transtripts involved in fusion geneENST00000317025, ENST00000433384, 
ENST00000527502, ENST00000316985, 
ENST00000525081, 		ENST00000496629, 
ENST00000425967, ENST00000326324, 
ENST00000335922, ENST00000341462, 
ENST00000356207, ENST00000397091, 
ENST00000397108, ENST00000397113, 
ENST00000447712, ENST00000532791, 
ENST00000397103, 
Fusion gene scores* DoF score31 X 27 X 13=1088125 X 34 X 7=5950
# samples 4622
** MAII scorelog2(46/10881*10)=-4.56403347974706
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(22/5950*10)=-4.75731423955801
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: WHSC1L1 [Title/Abstract] AND FGFR1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointWHSC1L1(38239317)-FGFR1(38315052), # samples:6
Anticipated loss of major functional domain due to fusion event.WHSC1L1-FGFR1 seems lost the major protein functional domain in Hgene partner, which is a epigenetic factor due to the frame-shifted ORF.
WHSC1L1-FGFR1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
WHSC1L1-FGFR1 seems lost the major protein functional domain in Hgene partner, which is a tumor suppressor due to the frame-shifted ORF.
WHSC1L1-FGFR1 seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF.
WHSC1L1-FGFR1 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
WHSC1L1-FGFR1 seems lost the major protein functional domain in Tgene partner, which is a kinase due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneWHSC1L1

GO:0016571

histone methylation

16682010

TgeneFGFR1

GO:0008284

positive regulation of cell proliferation

8663044

TgeneFGFR1

GO:0008543

fibroblast growth factor receptor signaling pathway

8663044

TgeneFGFR1

GO:0010863

positive regulation of phospholipase C activity

18480409

TgeneFGFR1

GO:0018108

peptidyl-tyrosine phosphorylation

8622701|18480409

TgeneFGFR1

GO:0043406

positive regulation of MAP kinase activity

8622701|18480409

TgeneFGFR1

GO:0046777

protein autophosphorylation

8622701

TgeneFGFR1

GO:2000546

positive regulation of endothelial cell chemotaxis to fibroblast growth factor

21885851


check buttonFusion gene breakpoints across WHSC1L1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across FGFR1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-C8-A26X-01AWHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
ChimerDB4BRCATCGA-E2-A15A-01AWHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
ChimerDB4BRCATCGA-E2-A15A-01AWHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
ChimerDB4BRCATCGA-E2-A15A-06AWHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
ChimerDB4BRCATCGA-E2-A15AWHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
ChimerDB4LUADTCGA-44-4112-01AWHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
ChimerDB4LUSCTCGA-77-8008WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-


Top

Fusion Gene ORF analysis for WHSC1L1-FGFR1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000317025ENST00000496629WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
5CDS-intronENST00000317025ENST00000496629WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
5CDS-intronENST00000433384ENST00000496629WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
5CDS-intronENST00000433384ENST00000496629WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
5CDS-intronENST00000527502ENST00000496629WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
5CDS-intronENST00000527502ENST00000496629WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
5UTR-3CDSENST00000316985ENST00000425967WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
5UTR-3CDSENST00000316985ENST00000425967WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
5UTR-3CDSENST00000317025ENST00000425967WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
5UTR-3CDSENST00000317025ENST00000425967WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
5UTR-3CDSENST00000433384ENST00000425967WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
5UTR-3CDSENST00000433384ENST00000425967WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
5UTR-3CDSENST00000527502ENST00000425967WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
5UTR-3CDSENST00000527502ENST00000425967WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000316985ENST00000326324WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000316985ENST00000326324WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000316985ENST00000335922WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000316985ENST00000335922WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000316985ENST00000341462WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000316985ENST00000341462WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000316985ENST00000356207WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000316985ENST00000356207WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000316985ENST00000397091WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000316985ENST00000397091WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000316985ENST00000397108WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
5UTR-5UTRENST00000316985ENST00000397108WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000316985ENST00000397108WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000316985ENST00000397113WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000316985ENST00000397113WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000316985ENST00000425967WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
5UTR-5UTRENST00000316985ENST00000447712WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000316985ENST00000447712WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000316985ENST00000532791WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000316985ENST00000532791WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000317025ENST00000326324WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000317025ENST00000326324WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000317025ENST00000335922WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000317025ENST00000335922WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000317025ENST00000341462WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000317025ENST00000341462WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000317025ENST00000356207WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000317025ENST00000356207WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000317025ENST00000397091WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000317025ENST00000397091WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000317025ENST00000397108WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
5UTR-5UTRENST00000317025ENST00000397108WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000317025ENST00000397108WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000317025ENST00000397113WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000317025ENST00000397113WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000317025ENST00000425967WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
5UTR-5UTRENST00000317025ENST00000447712WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000317025ENST00000447712WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000317025ENST00000532791WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000317025ENST00000532791WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000433384ENST00000326324WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000433384ENST00000326324WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000433384ENST00000335922WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000433384ENST00000335922WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000433384ENST00000341462WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000433384ENST00000341462WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000433384ENST00000356207WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000433384ENST00000356207WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000433384ENST00000397091WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000433384ENST00000397091WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000433384ENST00000397108WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
5UTR-5UTRENST00000433384ENST00000397108WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000433384ENST00000397108WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000433384ENST00000397113WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000433384ENST00000397113WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000433384ENST00000425967WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
5UTR-5UTRENST00000433384ENST00000447712WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000433384ENST00000447712WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000433384ENST00000532791WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000433384ENST00000532791WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000527502ENST00000326324WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000527502ENST00000326324WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000527502ENST00000335922WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000527502ENST00000335922WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000527502ENST00000341462WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000527502ENST00000341462WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000527502ENST00000356207WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000527502ENST00000356207WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000527502ENST00000397091WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000527502ENST00000397091WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000527502ENST00000397108WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
5UTR-5UTRENST00000527502ENST00000397108WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000527502ENST00000397108WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000527502ENST00000397113WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000527502ENST00000397113WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000527502ENST00000425967WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
5UTR-5UTRENST00000527502ENST00000447712WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000527502ENST00000447712WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000527502ENST00000532791WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
5UTR-5UTRENST00000527502ENST00000532791WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
5UTR-intronENST00000316985ENST00000326324WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
5UTR-intronENST00000316985ENST00000335922WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
5UTR-intronENST00000316985ENST00000341462WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
5UTR-intronENST00000316985ENST00000356207WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
5UTR-intronENST00000316985ENST00000397091WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
5UTR-intronENST00000316985ENST00000397103WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
5UTR-intronENST00000316985ENST00000397103WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
5UTR-intronENST00000316985ENST00000397103WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
5UTR-intronENST00000316985ENST00000397113WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
5UTR-intronENST00000316985ENST00000447712WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
5UTR-intronENST00000316985ENST00000496629WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
5UTR-intronENST00000316985ENST00000496629WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
5UTR-intronENST00000316985ENST00000496629WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
5UTR-intronENST00000316985ENST00000532791WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
5UTR-intronENST00000317025ENST00000326324WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
5UTR-intronENST00000317025ENST00000335922WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
5UTR-intronENST00000317025ENST00000341462WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
5UTR-intronENST00000317025ENST00000356207WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
5UTR-intronENST00000317025ENST00000397091WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
5UTR-intronENST00000317025ENST00000397103WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
5UTR-intronENST00000317025ENST00000397103WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
5UTR-intronENST00000317025ENST00000397103WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
5UTR-intronENST00000317025ENST00000397113WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
5UTR-intronENST00000317025ENST00000447712WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
5UTR-intronENST00000317025ENST00000496629WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
5UTR-intronENST00000317025ENST00000496629WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
5UTR-intronENST00000317025ENST00000496629WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
5UTR-intronENST00000317025ENST00000532791WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
5UTR-intronENST00000433384ENST00000326324WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
5UTR-intronENST00000433384ENST00000335922WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
5UTR-intronENST00000433384ENST00000341462WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
5UTR-intronENST00000433384ENST00000356207WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
5UTR-intronENST00000433384ENST00000397091WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
5UTR-intronENST00000433384ENST00000397103WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
5UTR-intronENST00000433384ENST00000397103WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
5UTR-intronENST00000433384ENST00000397103WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
5UTR-intronENST00000433384ENST00000397113WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
5UTR-intronENST00000433384ENST00000447712WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
5UTR-intronENST00000433384ENST00000496629WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
5UTR-intronENST00000433384ENST00000496629WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
5UTR-intronENST00000433384ENST00000496629WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
5UTR-intronENST00000433384ENST00000532791WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
5UTR-intronENST00000527502ENST00000326324WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
5UTR-intronENST00000527502ENST00000335922WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
5UTR-intronENST00000527502ENST00000341462WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
5UTR-intronENST00000527502ENST00000356207WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
5UTR-intronENST00000527502ENST00000397091WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
5UTR-intronENST00000527502ENST00000397103WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
5UTR-intronENST00000527502ENST00000397103WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
5UTR-intronENST00000527502ENST00000397103WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
5UTR-intronENST00000527502ENST00000397113WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
5UTR-intronENST00000527502ENST00000447712WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
5UTR-intronENST00000527502ENST00000496629WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
5UTR-intronENST00000527502ENST00000496629WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
5UTR-intronENST00000527502ENST00000496629WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
5UTR-intronENST00000527502ENST00000532791WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
Frame-shiftENST00000317025ENST00000326324WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
Frame-shiftENST00000317025ENST00000326324WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
Frame-shiftENST00000317025ENST00000335922WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
Frame-shiftENST00000317025ENST00000335922WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
Frame-shiftENST00000317025ENST00000341462WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
Frame-shiftENST00000317025ENST00000356207WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
Frame-shiftENST00000317025ENST00000356207WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
Frame-shiftENST00000317025ENST00000397091WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
Frame-shiftENST00000317025ENST00000397091WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
Frame-shiftENST00000317025ENST00000397103WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
Frame-shiftENST00000317025ENST00000397103WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
Frame-shiftENST00000317025ENST00000397108WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
Frame-shiftENST00000317025ENST00000397108WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
Frame-shiftENST00000317025ENST00000397113WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
Frame-shiftENST00000317025ENST00000397113WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
Frame-shiftENST00000317025ENST00000425967WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
Frame-shiftENST00000317025ENST00000425967WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
Frame-shiftENST00000317025ENST00000447712WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
Frame-shiftENST00000317025ENST00000447712WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
Frame-shiftENST00000317025ENST00000532791WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
Frame-shiftENST00000317025ENST00000532791WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
Frame-shiftENST00000433384ENST00000326324WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
Frame-shiftENST00000433384ENST00000326324WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
Frame-shiftENST00000433384ENST00000335922WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
Frame-shiftENST00000433384ENST00000335922WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
Frame-shiftENST00000433384ENST00000341462WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
Frame-shiftENST00000433384ENST00000356207WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
Frame-shiftENST00000433384ENST00000356207WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
Frame-shiftENST00000433384ENST00000397091WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
Frame-shiftENST00000433384ENST00000397091WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
Frame-shiftENST00000433384ENST00000397103WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
Frame-shiftENST00000433384ENST00000397103WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
Frame-shiftENST00000433384ENST00000397108WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
Frame-shiftENST00000433384ENST00000397108WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
Frame-shiftENST00000433384ENST00000397113WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
Frame-shiftENST00000433384ENST00000397113WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
Frame-shiftENST00000433384ENST00000425967WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
Frame-shiftENST00000433384ENST00000425967WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
Frame-shiftENST00000433384ENST00000447712WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
Frame-shiftENST00000433384ENST00000447712WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
Frame-shiftENST00000433384ENST00000532791WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
Frame-shiftENST00000433384ENST00000532791WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
Frame-shiftENST00000527502ENST00000326324WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
Frame-shiftENST00000527502ENST00000326324WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
Frame-shiftENST00000527502ENST00000335922WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
Frame-shiftENST00000527502ENST00000335922WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
Frame-shiftENST00000527502ENST00000341462WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
Frame-shiftENST00000527502ENST00000356207WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
Frame-shiftENST00000527502ENST00000356207WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
Frame-shiftENST00000527502ENST00000397091WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
Frame-shiftENST00000527502ENST00000397091WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
Frame-shiftENST00000527502ENST00000397103WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
Frame-shiftENST00000527502ENST00000397103WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
Frame-shiftENST00000527502ENST00000397108WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
Frame-shiftENST00000527502ENST00000397108WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
Frame-shiftENST00000527502ENST00000397113WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
Frame-shiftENST00000527502ENST00000397113WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
Frame-shiftENST00000527502ENST00000425967WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
Frame-shiftENST00000527502ENST00000425967WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
Frame-shiftENST00000527502ENST00000447712WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
Frame-shiftENST00000527502ENST00000447712WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
Frame-shiftENST00000527502ENST00000532791WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
Frame-shiftENST00000527502ENST00000532791WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
In-frameENST00000317025ENST00000341462WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
In-frameENST00000433384ENST00000341462WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
In-frameENST00000527502ENST00000341462WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
intron-3CDSENST00000316985ENST00000326324WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
intron-3CDSENST00000316985ENST00000326324WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
intron-3CDSENST00000316985ENST00000335922WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
intron-3CDSENST00000316985ENST00000335922WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
intron-3CDSENST00000316985ENST00000341462WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
intron-3CDSENST00000316985ENST00000341462WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
intron-3CDSENST00000316985ENST00000356207WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
intron-3CDSENST00000316985ENST00000356207WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
intron-3CDSENST00000316985ENST00000397091WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
intron-3CDSENST00000316985ENST00000397091WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
intron-3CDSENST00000316985ENST00000397103WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
intron-3CDSENST00000316985ENST00000397103WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
intron-3CDSENST00000316985ENST00000397108WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
intron-3CDSENST00000316985ENST00000397108WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
intron-3CDSENST00000316985ENST00000397113WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
intron-3CDSENST00000316985ENST00000397113WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
intron-3CDSENST00000316985ENST00000425967WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
intron-3CDSENST00000316985ENST00000425967WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
intron-3CDSENST00000316985ENST00000447712WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
intron-3CDSENST00000316985ENST00000447712WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
intron-3CDSENST00000316985ENST00000532791WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
intron-3CDSENST00000316985ENST00000532791WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
intron-3CDSENST00000525081ENST00000326324WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
intron-3CDSENST00000525081ENST00000326324WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
intron-3CDSENST00000525081ENST00000335922WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
intron-3CDSENST00000525081ENST00000335922WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
intron-3CDSENST00000525081ENST00000341462WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
intron-3CDSENST00000525081ENST00000341462WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
intron-3CDSENST00000525081ENST00000356207WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
intron-3CDSENST00000525081ENST00000356207WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
intron-3CDSENST00000525081ENST00000397091WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
intron-3CDSENST00000525081ENST00000397091WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
intron-3CDSENST00000525081ENST00000397103WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
intron-3CDSENST00000525081ENST00000397103WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
intron-3CDSENST00000525081ENST00000397108WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
intron-3CDSENST00000525081ENST00000397108WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
intron-3CDSENST00000525081ENST00000397113WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
intron-3CDSENST00000525081ENST00000397113WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
intron-3CDSENST00000525081ENST00000425967WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
intron-3CDSENST00000525081ENST00000425967WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
intron-3CDSENST00000525081ENST00000425967WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
intron-3CDSENST00000525081ENST00000425967WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
intron-3CDSENST00000525081ENST00000447712WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
intron-3CDSENST00000525081ENST00000447712WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
intron-3CDSENST00000525081ENST00000532791WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
intron-3CDSENST00000525081ENST00000532791WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
intron-5UTRENST00000525081ENST00000326324WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
intron-5UTRENST00000525081ENST00000326324WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
intron-5UTRENST00000525081ENST00000335922WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
intron-5UTRENST00000525081ENST00000335922WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
intron-5UTRENST00000525081ENST00000341462WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
intron-5UTRENST00000525081ENST00000341462WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
intron-5UTRENST00000525081ENST00000356207WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
intron-5UTRENST00000525081ENST00000356207WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
intron-5UTRENST00000525081ENST00000397091WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
intron-5UTRENST00000525081ENST00000397091WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
intron-5UTRENST00000525081ENST00000397108WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
intron-5UTRENST00000525081ENST00000397108WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
intron-5UTRENST00000525081ENST00000397108WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
intron-5UTRENST00000525081ENST00000397113WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
intron-5UTRENST00000525081ENST00000397113WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
intron-5UTRENST00000525081ENST00000425967WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
intron-5UTRENST00000525081ENST00000447712WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
intron-5UTRENST00000525081ENST00000447712WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
intron-5UTRENST00000525081ENST00000532791WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
intron-5UTRENST00000525081ENST00000532791WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
intron-intronENST00000316985ENST00000496629WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
intron-intronENST00000316985ENST00000496629WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
intron-intronENST00000525081ENST00000326324WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
intron-intronENST00000525081ENST00000335922WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
intron-intronENST00000525081ENST00000341462WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
intron-intronENST00000525081ENST00000356207WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
intron-intronENST00000525081ENST00000397091WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
intron-intronENST00000525081ENST00000397103WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
intron-intronENST00000525081ENST00000397103WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
intron-intronENST00000525081ENST00000397103WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
intron-intronENST00000525081ENST00000397113WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
intron-intronENST00000525081ENST00000447712WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
intron-intronENST00000525081ENST00000496629WHSC1L1chr8

38162105

-FGFR1chr8

38285611

-
intron-intronENST00000525081ENST00000496629WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-
intron-intronENST00000525081ENST00000496629WHSC1L1chr8

38239317

-FGFR1chr8

38315052

-
intron-intronENST00000525081ENST00000496629WHSC1L1chr8

38239316

-FGFR1chr8

38315052

-
intron-intronENST00000525081ENST00000496629WHSC1L1chr8

38162104

-FGFR1chr8

38277253

-
intron-intronENST00000525081ENST00000532791WHSC1L1chr8

38239317

-FGFR1chr8

38318773

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000317025WHSC1L1chr838162104-ENST00000341462FGFR1chr838277253-700431295183265915
ENST00000433384WHSC1L1chr838162104-ENST00000341462FGFR1chr838277253-697731024913238915
ENST00000527502WHSC1L1chr838162104-ENST00000341462FGFR1chr838277253-65782703922839915

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000317025ENST00000341462WHSC1L1chr838162104-FGFR1chr838277253-0.0007429110.999257
ENST00000433384ENST00000341462WHSC1L1chr838162104-FGFR1chr838277253-0.0007472240.99925274
ENST00000527502ENST00000341462WHSC1L1chr838162104-FGFR1chr838277253-0.0006238560.9993761

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Fusion Genomic Features for WHSC1L1-FGFR1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for WHSC1L1-FGFR1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr8:38239317/chr8:38315052)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.FGFR1

Q9NVK5

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: May be involved in wound healing pathway. {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneWHSC1L1chr8:38162104chr8:38277253ENST00000317025-1424270_3338701438.0DomainPWWP 1
HgeneWHSC1L1chr8:38162104chr8:38277253ENST00000433384-1423270_3338701389.0DomainPWWP 1
HgeneWHSC1L1chr8:38162104chr8:38277253ENST00000317025-1424701_7488701438.0Zinc fingerPHD-type 1
HgeneWHSC1L1chr8:38162104chr8:38277253ENST00000317025-1424749_8058701438.0Zinc fingerPHD-type 2
HgeneWHSC1L1chr8:38162104chr8:38277253ENST00000433384-1423701_7488701389.0Zinc fingerPHD-type 1
HgeneWHSC1L1chr8:38162104chr8:38277253ENST00000433384-1423749_8058701389.0Zinc fingerPHD-type 2
TgeneFGFR1chr8:38162104chr8:38277253ENST00000326324617478_767269732.0DomainProtein kinase
TgeneFGFR1chr8:38162104chr8:38277253ENST00000335922819478_767352813.0DomainProtein kinase
TgeneFGFR1chr8:38162104chr8:38277253ENST00000356207617478_767271734.0DomainProtein kinase
TgeneFGFR1chr8:38162104chr8:38277253ENST00000397091718478_767358821.0DomainProtein kinase
TgeneFGFR1chr8:38162104chr8:38277253ENST00000397108819478_767358821.0DomainProtein kinase
TgeneFGFR1chr8:38162104chr8:38277253ENST00000397113718478_767358821.0DomainProtein kinase
TgeneFGFR1chr8:38162104chr8:38277253ENST00000425967819478_767391854.0DomainProtein kinase
TgeneFGFR1chr8:38162104chr8:38277253ENST00000447712718478_767360823.0DomainProtein kinase
TgeneFGFR1chr8:38162104chr8:38277253ENST00000532791718478_767360821.0DomainProtein kinase
TgeneFGFR1chr8:38162104chr8:38277253ENST00000326324617484_490269732.0Nucleotide bindingNote=ATP
TgeneFGFR1chr8:38162104chr8:38277253ENST00000326324617562_564269732.0Nucleotide bindingNote=ATP
TgeneFGFR1chr8:38162104chr8:38277253ENST00000335922819484_490352813.0Nucleotide bindingNote=ATP
TgeneFGFR1chr8:38162104chr8:38277253ENST00000335922819562_564352813.0Nucleotide bindingNote=ATP
TgeneFGFR1chr8:38162104chr8:38277253ENST00000356207617484_490271734.0Nucleotide bindingNote=ATP
TgeneFGFR1chr8:38162104chr8:38277253ENST00000356207617562_564271734.0Nucleotide bindingNote=ATP
TgeneFGFR1chr8:38162104chr8:38277253ENST00000397091718484_490358821.0Nucleotide bindingNote=ATP
TgeneFGFR1chr8:38162104chr8:38277253ENST00000397091718562_564358821.0Nucleotide bindingNote=ATP
TgeneFGFR1chr8:38162104chr8:38277253ENST00000397108819484_490358821.0Nucleotide bindingNote=ATP
TgeneFGFR1chr8:38162104chr8:38277253ENST00000397108819562_564358821.0Nucleotide bindingNote=ATP
TgeneFGFR1chr8:38162104chr8:38277253ENST00000397113718484_490358821.0Nucleotide bindingNote=ATP
TgeneFGFR1chr8:38162104chr8:38277253ENST00000397113718562_564358821.0Nucleotide bindingNote=ATP
TgeneFGFR1chr8:38162104chr8:38277253ENST00000425967819484_490391854.0Nucleotide bindingNote=ATP
TgeneFGFR1chr8:38162104chr8:38277253ENST00000425967819562_564391854.0Nucleotide bindingNote=ATP
TgeneFGFR1chr8:38162104chr8:38277253ENST00000447712718484_490360823.0Nucleotide bindingNote=ATP
TgeneFGFR1chr8:38162104chr8:38277253ENST00000447712718562_564360823.0Nucleotide bindingNote=ATP
TgeneFGFR1chr8:38162104chr8:38277253ENST00000532791718484_490360821.0Nucleotide bindingNote=ATP
TgeneFGFR1chr8:38162104chr8:38277253ENST00000532791718562_564360821.0Nucleotide bindingNote=ATP
TgeneFGFR1chr8:38162104chr8:38277253ENST00000326324617398_822269732.0Topological domainCytoplasmic
TgeneFGFR1chr8:38162104chr8:38277253ENST00000335922819398_822352813.0Topological domainCytoplasmic
TgeneFGFR1chr8:38162104chr8:38277253ENST00000356207617398_822271734.0Topological domainCytoplasmic
TgeneFGFR1chr8:38162104chr8:38277253ENST00000397091718398_822358821.0Topological domainCytoplasmic
TgeneFGFR1chr8:38162104chr8:38277253ENST00000397108819398_822358821.0Topological domainCytoplasmic
TgeneFGFR1chr8:38162104chr8:38277253ENST00000397113718398_822358821.0Topological domainCytoplasmic
TgeneFGFR1chr8:38162104chr8:38277253ENST00000425967819398_822391854.0Topological domainCytoplasmic
TgeneFGFR1chr8:38162104chr8:38277253ENST00000447712718398_822360823.0Topological domainCytoplasmic
TgeneFGFR1chr8:38162104chr8:38277253ENST00000532791718398_822360821.0Topological domainCytoplasmic
TgeneFGFR1chr8:38162104chr8:38277253ENST00000326324617377_397269732.0TransmembraneHelical
TgeneFGFR1chr8:38162104chr8:38277253ENST00000335922819377_397352813.0TransmembraneHelical
TgeneFGFR1chr8:38162104chr8:38277253ENST00000356207617377_397271734.0TransmembraneHelical
TgeneFGFR1chr8:38162104chr8:38277253ENST00000397091718377_397358821.0TransmembraneHelical
TgeneFGFR1chr8:38162104chr8:38277253ENST00000397108819377_397358821.0TransmembraneHelical
TgeneFGFR1chr8:38162104chr8:38277253ENST00000397113718377_397358821.0TransmembraneHelical
TgeneFGFR1chr8:38162104chr8:38277253ENST00000447712718377_397360823.0TransmembraneHelical
TgeneFGFR1chr8:38162104chr8:38277253ENST00000532791718377_397360821.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneWHSC1L1chr8:38162104chr8:38277253ENST00000316985-1101033_10690646.0Coiled coilOntology_term=ECO:0000255
HgeneWHSC1L1chr8:38162104chr8:38277253ENST00000317025-14241033_10698701438.0Coiled coilOntology_term=ECO:0000255
HgeneWHSC1L1chr8:38162104chr8:38277253ENST00000433384-14231033_10698701389.0Coiled coilOntology_term=ECO:0000255
HgeneWHSC1L1chr8:38162104chr8:38277253ENST00000316985-1101093_11430646.0DomainAWS
HgeneWHSC1L1chr8:38162104chr8:38277253ENST00000316985-1101145_12620646.0DomainSET
HgeneWHSC1L1chr8:38162104chr8:38277253ENST00000316985-1101269_12850646.0DomainPost-SET
HgeneWHSC1L1chr8:38162104chr8:38277253ENST00000316985-110270_3330646.0DomainPWWP 1
HgeneWHSC1L1chr8:38162104chr8:38277253ENST00000316985-110960_10220646.0DomainPWWP 2
HgeneWHSC1L1chr8:38162104chr8:38277253ENST00000317025-14241093_11438701438.0DomainAWS
HgeneWHSC1L1chr8:38162104chr8:38277253ENST00000317025-14241145_12628701438.0DomainSET
HgeneWHSC1L1chr8:38162104chr8:38277253ENST00000317025-14241269_12858701438.0DomainPost-SET
HgeneWHSC1L1chr8:38162104chr8:38277253ENST00000317025-1424960_10228701438.0DomainPWWP 2
HgeneWHSC1L1chr8:38162104chr8:38277253ENST00000433384-14231093_11438701389.0DomainAWS
HgeneWHSC1L1chr8:38162104chr8:38277253ENST00000433384-14231145_12628701389.0DomainSET
HgeneWHSC1L1chr8:38162104chr8:38277253ENST00000433384-14231269_12858701389.0DomainPost-SET
HgeneWHSC1L1chr8:38162104chr8:38277253ENST00000433384-1423960_10228701389.0DomainPWWP 2
HgeneWHSC1L1chr8:38162104chr8:38277253ENST00000316985-1101321_13680646.0Zinc fingerPHD-type 4%3B atypical
HgeneWHSC1L1chr8:38162104chr8:38277253ENST00000316985-110701_7480646.0Zinc fingerPHD-type 1
HgeneWHSC1L1chr8:38162104chr8:38277253ENST00000316985-110749_8050646.0Zinc fingerPHD-type 2
HgeneWHSC1L1chr8:38162104chr8:38277253ENST00000316985-110862_9550646.0Zinc fingerPHD-type 3
HgeneWHSC1L1chr8:38162104chr8:38277253ENST00000317025-14241321_13688701438.0Zinc fingerPHD-type 4%3B atypical
HgeneWHSC1L1chr8:38162104chr8:38277253ENST00000317025-1424862_9558701438.0Zinc fingerPHD-type 3
HgeneWHSC1L1chr8:38162104chr8:38277253ENST00000433384-14231321_13688701389.0Zinc fingerPHD-type 4%3B atypical
HgeneWHSC1L1chr8:38162104chr8:38277253ENST00000433384-1423862_9558701389.0Zinc fingerPHD-type 3
TgeneFGFR1chr8:38162104chr8:38277253ENST00000326324617158_246269732.0DomainNote=Ig-like C2-type 2
TgeneFGFR1chr8:38162104chr8:38277253ENST00000326324617255_357269732.0DomainNote=Ig-like C2-type 3
TgeneFGFR1chr8:38162104chr8:38277253ENST0000032632461725_119269732.0DomainNote=Ig-like C2-type 1
TgeneFGFR1chr8:38162104chr8:38277253ENST00000335922819158_246352813.0DomainNote=Ig-like C2-type 2
TgeneFGFR1chr8:38162104chr8:38277253ENST00000335922819255_357352813.0DomainNote=Ig-like C2-type 3
TgeneFGFR1chr8:38162104chr8:38277253ENST0000033592281925_119352813.0DomainNote=Ig-like C2-type 1
TgeneFGFR1chr8:38162104chr8:38277253ENST00000356207617158_246271734.0DomainNote=Ig-like C2-type 2
TgeneFGFR1chr8:38162104chr8:38277253ENST00000356207617255_357271734.0DomainNote=Ig-like C2-type 3
TgeneFGFR1chr8:38162104chr8:38277253ENST0000035620761725_119271734.0DomainNote=Ig-like C2-type 1
TgeneFGFR1chr8:38162104chr8:38277253ENST00000397091718158_246358821.0DomainNote=Ig-like C2-type 2
TgeneFGFR1chr8:38162104chr8:38277253ENST00000397091718255_357358821.0DomainNote=Ig-like C2-type 3
TgeneFGFR1chr8:38162104chr8:38277253ENST0000039709171825_119358821.0DomainNote=Ig-like C2-type 1
TgeneFGFR1chr8:38162104chr8:38277253ENST00000397108819158_246358821.0DomainNote=Ig-like C2-type 2
TgeneFGFR1chr8:38162104chr8:38277253ENST00000397108819255_357358821.0DomainNote=Ig-like C2-type 3
TgeneFGFR1chr8:38162104chr8:38277253ENST0000039710881925_119358821.0DomainNote=Ig-like C2-type 1
TgeneFGFR1chr8:38162104chr8:38277253ENST00000397113718158_246358821.0DomainNote=Ig-like C2-type 2
TgeneFGFR1chr8:38162104chr8:38277253ENST00000397113718255_357358821.0DomainNote=Ig-like C2-type 3
TgeneFGFR1chr8:38162104chr8:38277253ENST0000039711371825_119358821.0DomainNote=Ig-like C2-type 1
TgeneFGFR1chr8:38162104chr8:38277253ENST00000425967819158_246391854.0DomainNote=Ig-like C2-type 2
TgeneFGFR1chr8:38162104chr8:38277253ENST00000425967819255_357391854.0DomainNote=Ig-like C2-type 3
TgeneFGFR1chr8:38162104chr8:38277253ENST0000042596781925_119391854.0DomainNote=Ig-like C2-type 1
TgeneFGFR1chr8:38162104chr8:38277253ENST00000447712718158_246360823.0DomainNote=Ig-like C2-type 2
TgeneFGFR1chr8:38162104chr8:38277253ENST00000447712718255_357360823.0DomainNote=Ig-like C2-type 3
TgeneFGFR1chr8:38162104chr8:38277253ENST0000044771271825_119360823.0DomainNote=Ig-like C2-type 1
TgeneFGFR1chr8:38162104chr8:38277253ENST00000532791718158_246360821.0DomainNote=Ig-like C2-type 2
TgeneFGFR1chr8:38162104chr8:38277253ENST00000532791718255_357360821.0DomainNote=Ig-like C2-type 3
TgeneFGFR1chr8:38162104chr8:38277253ENST0000053279171825_119360821.0DomainNote=Ig-like C2-type 1
TgeneFGFR1chr8:38162104chr8:38277253ENST00000326324617160_177269732.0RegionNote=Heparin-binding
TgeneFGFR1chr8:38162104chr8:38277253ENST00000335922819160_177352813.0RegionNote=Heparin-binding
TgeneFGFR1chr8:38162104chr8:38277253ENST00000356207617160_177271734.0RegionNote=Heparin-binding
TgeneFGFR1chr8:38162104chr8:38277253ENST00000397091718160_177358821.0RegionNote=Heparin-binding
TgeneFGFR1chr8:38162104chr8:38277253ENST00000397108819160_177358821.0RegionNote=Heparin-binding
TgeneFGFR1chr8:38162104chr8:38277253ENST00000397113718160_177358821.0RegionNote=Heparin-binding
TgeneFGFR1chr8:38162104chr8:38277253ENST00000425967819160_177391854.0RegionNote=Heparin-binding
TgeneFGFR1chr8:38162104chr8:38277253ENST00000447712718160_177360823.0RegionNote=Heparin-binding
TgeneFGFR1chr8:38162104chr8:38277253ENST00000532791718160_177360821.0RegionNote=Heparin-binding
TgeneFGFR1chr8:38162104chr8:38277253ENST0000032632461722_376269732.0Topological domainExtracellular
TgeneFGFR1chr8:38162104chr8:38277253ENST0000033592281922_376352813.0Topological domainExtracellular
TgeneFGFR1chr8:38162104chr8:38277253ENST0000035620761722_376271734.0Topological domainExtracellular
TgeneFGFR1chr8:38162104chr8:38277253ENST0000039709171822_376358821.0Topological domainExtracellular
TgeneFGFR1chr8:38162104chr8:38277253ENST0000039710881922_376358821.0Topological domainExtracellular
TgeneFGFR1chr8:38162104chr8:38277253ENST0000039711371822_376358821.0Topological domainExtracellular
TgeneFGFR1chr8:38162104chr8:38277253ENST0000042596781922_376391854.0Topological domainExtracellular
TgeneFGFR1chr8:38162104chr8:38277253ENST0000044771271822_376360823.0Topological domainExtracellular
TgeneFGFR1chr8:38162104chr8:38277253ENST0000053279171822_376360821.0Topological domainExtracellular
TgeneFGFR1chr8:38162104chr8:38277253ENST00000425967819377_397391854.0TransmembraneHelical


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Fusion Gene Sequence for WHSC1L1-FGFR1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>99203_99203_1_WHSC1L1-FGFR1_WHSC1L1_chr8_38162104_ENST00000317025_FGFR1_chr8_38277253_ENST00000341462_length(transcript)=7004nt_BP=3129nt
GGGGGCTTTGTGCGCGGCGGCGGCGGGAGAGGCGGCGGCGGCGGCCAGCACGGAGGCGGAGGCCGAGGGGGCTGTGCACAGGTCGCCGCG
GAGAGGCGTGCGAATTCCGAGCCGAGCGCCGAGGACCGTGCTACCCAGGCCGGGCTGCCAGCCGCAGGCTCCTCTCTGGCAGCAGCGGCG
GCGCGGCGACCCCCGTCCCTCGGCCTCCCCTTCCCATCCCACCTCCCGAGCCTTCCTCTTCCCGCAGCACGCCCGGCCCGGCCCGGCCGT
GGCCCTCCTCAGTGCCGGCCGCCATGGCAGAGGCGTCCGGCGCGGGGAAAATCTAGCCCGGGGATTTCATGCGGCCTAGCTCGGTTCCGC
CTCCTCCTCGCGCGGCCCCAGCGGCTGCCCGCACCCCAGCCCCACTCCGGGCCTCCGTGTCTCTCCTGTGATCGCACTGACACGGCCGGG
GGGTTAGAATGGAACAAACTGAAGGCCCGATGAGAGAAAGGGAAAGTTAAGGATGCTGGAGCAGAACAATGGATTTCTCTTTCTCTTTCA
TGCAAGGGATCATGGGAAACACAATTCAGCAACCACCTCAACTCATTGACTCCGCCAACATCCGTCAGGAGGATGCCTTTGATAACAACA
GTGACATTGCTGAAGATGGTGGCCAGACACCATATGAAGCTACTTTGCAGCAAGGCTTTCAGTACCCAGCTACAACAGAAGATCTTCCTC
CACTCACAAATGGGTATCCATCATCAATCAGTGTGTATGAAACTCAAACCAAATACCAGTCATATAATCAGTATCCTAATGGGTCAGCCA
ATGGCTTTGGTGCAGTTAGAAACTTTAGCCCCACTGACTATTATCATTCAGAAATTCCAAACACAAGACCACATGAAATTCTGGAAAAAC
CTTCCCCTCCACAGCCACCACCTCCTCCTTCGGTACCACAAACTGTGATTCCAAAGAAGACTGGCTCACCTGAAATTAAACTAAAAATAA
CCAAAACTATCCAGAATGGCAGGGAATTGTTTGAGTCTTCCCTTTGTGGAGACCTTTTAAATGAAGTACAGGCAAGTGAGCACACGAAAT
CAAAGCATGAAAGCAGAAAAGAAAAGAGGAAAAAAAGCAACAAGCATGACTCATCAAGATCTGAAGAGCGCAAGTCACACAAAATCCCCA
AATTAGAACCAGAGGAACAAAATAGACCAAATGAGAGGGTTGACACTGTATCAGAAAAACCAAGGGAAGAACCAGTACTAAAAGAGGAAG
CCCCAGTTCAGCCAATACTATCTTCTGTTCCAACAACGGAAGTGTCCACTGGTGTTAAGTTTCAGGTTGGCGATCTTGTGTGGTCCAAGG
TGGGAACCTATCCTTGGTGGCCTTGTATGGTTTCAAGTGATCCCCAGCTTGAGGTTCATACTAAAATTAACACAAGAGGTGCCCGAGAAT
ATCATGTCCAGTTTTTTAGCAACCAGCCAGAGAGGGCGTGGGTTCATGAAAAACGGGTACGAGAGTATAAAGGTCATAAACAGTATGAAG
AATTACTGGCTGAGGCAACCAAACAAGCCAGCAATCACTCTGAGAAACAAAAGATTCGGAAACCCCGACCTCAGAGAGAACGTGCTCAGT
GGGATATTGGCATTGCCCATGCAGAGAAAGCATTGAAAATGACTCGAGAAGAAAGAATAGAACAGTATACTTTTATTTACATTGATAAAC
AGCCTGAAGAGGCTTTATCCCAAGCAAAAAAGAGTGTTGCCTCCAAAACCGAAGTTAAAAAAACCCGACGACCAAGATCTGTGCTGAATA
CTCAGCCAGAACAGACCAATGCAGGGGAGGTGGCCTCCTCACTCTCAAGTACTGAAATTCGGAGACATAGCCAGAGGCGGCACACAAGTG
CGGAAGAGGAAGAGCCACCGCCTGTTAAAATAGCCTGGAAAACTGCGGCAGCAAGGAAATCCTTACCAGCTTCCATTACGATGCACAAAG
GGAGCCTGGATTTGCAGAAGTGTAACATGTCTCCAGTTGTGAAAATTGAACAAGTGTTTGCTCTTCAGAATGCTACAGGGGATGGGAAAT
TTATCGATCAATTTGTTTATTCAACAAAGGGAATTGGTAACAAAACAGAAATAAGTGTCAGGGGGCAAGACAGGCTTATAATTTCTACAC
CAAACCAGAGAAATGAAAAGCCAACGCAGAGTGTATCATCTCCTGAAGCAACATCTGGTTCTACAGGCTCAGTAGAAAAGAAGCAACAGA
GAAGATCAATTAGAACTCGTTCTGAATCAGAGAAATCCACTGAGGTTGTGCCAAAGAAGAAGATCAAAAAGGAGCAGGTTGAAACAGTTC
CTCAGGCTACAGTGAAGACTGGATTACAGAAAGGTGCCAGCGAGATTTCAGATTCCTGTAAACCTCTAAAGAAAAGGAGTCGCGCCTCAA
CTGATGTAGAAATGACTAGTTCAGCATACAGAGACACATCTGACTCCGATTCTAGAGGACTGAGTGACCTGCAGGTAGGCTTTGGAAAGC
AAGTAGATAGCCCTTCAGCTACTGCAGATGCAGACGTTTCTGATGTGCAGTCCATGGATTCAAGTTTGTCGAGAAGAGGCACTGGAATGA
GTAAGAAGGACACTGTATGTCAGATTTGTGAAAGCTCTGGTGACTCTCTGATTCCTTGTGAGGGAGAGTGCTGCAAACACTTTCACCTGG
AGTGCCTGGGATTGGCATCACTTCCTGATAGCAAGTTCATCTGCATGGAATGTAAAACTGGGCAGCACCCATGTTTTTCGTGTAAAGTGT
CTGGTAAAGATGTGAAGCGTTGTTCTGTTGGTGCTTGTGGGAAATTTTATCATGAAGCCTGTGTCCGCAAATTCCCCACTGCCATCTTTG
AATCAAAAGGATTCCGCTGTCCTCAGCACTGCTGCTCTGCCTGCTCTATGGAGAAAGATATCCACAAAGCAAGTAAAGGCCGCATGATGA
GATGTTTAAGATGTCCAGTTGCCTATCACTCTGGAGATGCTTGCATTGCGGCCGGAAGCATGTTAGTATCCTCCTACATTCTCATCTGTA
GTAATCATTCCAAACGGAGCAGTAATTCTTCTGCTGTAAATGTAGGCTTTTGTTTCGTTTGTGCCAGAGCTGGAAGAGAGGCCGGCAGTG
ATGACCTCGCCCCTGTACCTGGAGATCATCATCTATTGCACAGGGGCCTTCCTCATCTCCTGCATGGTGGGGTCGGTCATCGTCTACAAG
ATGAAGAGTGGTACCAAGAAGAGTGACTTCCACAGCCAGATGGCTGTGCACAAGCTGGCCAAGAGCATCCCTCTGCGCAGACAGGTAACA
GTGTCTGCTGACTCCAGTGCATCCATGAACTCTGGGGTTCTTCTGGTTCGGCCATCACGGCTCTCCTCCAGTGGGACTCCCATGCTAGCA
GGGGTCTCTGAGTATGAGCTTCCCGAAGACCCTCGCTGGGAGCTGCCTCGGGACAGACTGGTCTTAGGCAAACCCCTGGGAGAGGGCTGC
TTTGGGCAGGTGGTGTTGGCAGAGGCTATCGGGCTGGACAAGGACAAACCCAACCGTGTGACCAAAGTGGCTGTGAAGATGTTGAAGTCG
GACGCAACAGAGAAAGACTTGTCAGACCTGATCTCAGAAATGGAGATGATGAAGATGATCGGGAAGCATAAGAATATCATCAACCTGCTG
GGGGCCTGCACGCAGGATGGTCCCTTGTATGTCATCGTGGAGTATGCCTCCAAGGGCAACCTGCGGGAGTACCTGCAGGCCCGGAGGCCC
CCAGGGCTGGAATACTGCTACAACCCCAGCCACAACCCAGAGGAGCAGCTCTCCTCCAAGGACCTGGTGTCCTGCGCCTACCAGGTGGCC
CGAGGCATGGAGTATCTGGCCTCCAAGAAGTGCATACACCGAGACCTGGCAGCCAGGAATGTCCTGGTGACAGAGGACAATGTGATGAAG
ATAGCAGACTTTGGCCTCGCACGGGACATTCACCACATCGACTACTATAAAAAGACAACCAACGGCCGACTGCCTGTGAAGTGGATGGCA
CCCGAGGCATTATTTGACCGGATCTACACCCACCAGAGTGATGTGTGGTCTTTCGGGGTGCTCCTGTGGGAGATCTTCACTCTGGGCGGC
TCCCCATACCCCGGTGTGCCTGTGGAGGAACTTTTCAAGCTGCTGAAGGAGGGTCACCGCATGGACAAGCCCAGTAACTGCACCAACGAG
CTGTACATGATGATGCGGGACTGCTGGCATGCAGTGCCCTCACAGAGACCCACCTTCAAGCAGCTGGTGGAAGACCTGGACCGCATCGTG
GCCTTGACCTCCAACCAGGAGTACCTGGACCTGTCCATGCCCCTGGACCAGTACTCCCCCAGCTTTCCCGACACCCGGAGCTCTACGTGC
TCCTCAGGGGAGGATTCCGTCTTCTCTCATGAGCCGCTGCCCGAGGAGCCCTGCCTGCCCCGACACCCAGCCCAGCTTGCCAATGGCGGA
CTCAAACGCCGCTGACTGCCACCCACACGCCCTCCCCAGACTCCACCGTCAGCTGTAACCCTCACCCACAGCCCCTGCTGGGCCCACCAC
CTGTCCGTCCCTGTCCCCTTTCCTGCTGGCAGGAGCCGGCTGCCTACCAGGGGCCTTCCTGTGTGGCCTGCCTTCACCCCACTCAGCTCA
CCTCTCCCTCCACCTCCTCTCCACCTGCTGGTGAGAGGTGCAAAGAGGCAGATCTTTGCTGCCAGCCACTTCATCCCCTCCCAGATGTTG
GACCAACACCCCTCCCTGCCACCAGGCACTGCCTGGAGGGCAGGGAGTGGGAGCCAATGAACAGGCATGCAAGTGAGAGCTTCCTGAGCT
TTCTCCTGTCGGTTTGGTCTGTTTTGCCTTCACCCATAAGCCCCTCGCACTCTGGTGGCAGGTGCCTTGTCCTCAGGGCTACAGCAGTAG
GGAGGTCAGTGCTTCGTGCCTCGATTGAAGGTGACCTCTGCCCCAGATAGGTGGTGCCAGTGGCTTATTAATTCCGATACTAGTTTGCTT
TGCTGACCAAATGCCTGGTACCAGAGGATGGTGAGGCGAAGGCCAGGTTGGGGGCAGTGTTGTGGCCCTGGGGCCCAGCCCCAAACTGGG
GGCTCTGTATATAGCTATGAAGAAAACACAAAGTGTATAAATCTGAGTATATATTTACATGTCTTTTTAAAAGGGTCGTTACCAGAGATT
TACCCATCGGGTAAGATGCTCCTGGTGGCTGGGAGGCATCAGTTGCTATATATTAAAAACAAAAAAGAAAAAAAAGGAAAATGTTTTTAA
AAAGGTCATATATTTTTTGCTACTTTTGCTGTTTTATTTTTTTAAATTATGTTCTAAACCTATTTTCAGTTTAGGTCCCTCAATAAAAAT
TGCTGCTGCTTCATTTATCTATGGGCTGTATGAAAAGGGTGGGAATGTCCACTGGAAAGAAGGGACACCCACGGGCCCTGGGGCTAGGTC
TGTCCCGAGGGCACCGCATGCTCCCGGCGCAGGTTCCTTGTAACCTCTTCTTCCTAGGTCCTGCACCCAGACCTCACGACGCACCTCCTG
CCTCTCCGCTGCTTTTGGAAAGTCAGAAAAAGAAGATGTCTGCTTCGAGGGCAGGAACCCCATCCATGCAGTAGAGGCGCTGGGCAGAGA
GTCAAGGCCCAGCAGCCATCGACCATGGATGGTTTCCTCCAAGGAAACCGGTGGGGTTGGGCTGGGGAGGGGGCACCTACCTAGGAATAG
CCACGGGGTAGAGCTACAGTGATTAAGAGGAAAGCAAGGGCGCGGTTGCTCACGCCTGTAATCCCAGCACTTTGGGACACCGAGGTGGGC
AGATCACTTCAGGTCAGGAGTTTGAGACCAGCCTGGCCAACTTAGTGAAACCCCATCTCTACTAAAAATGCAAAAATTATCCAGGCATGG
TGGCACACGCCTGTAATCCCAGCTCCACAGGAGGCTGAGGCAGAATCCCTTGAAGCTGGGAGGCGGAGGTTGCAGTGAGCCGAGATTGCG
CCATTGCACTCCAGCCTGGGCAACAGAGAAAACAAAAAGGAAAACAAATGATGAAGGTCTGCAGAAACTGAAACCCAGACATGTGTCTGC
CCCCTCTATGTGGGCATGGTTTTGCCAGTGCTTCTAAGTGCAGGAGAACATGTCACCTGAGGCTAGTTTTGCATTCAGGTCCCTGGCTTC
GTTTCTTGTTGGTATGCCTCCCCAGATCGTCCTTCCTGTATCCATGTGACCAGACTGTATTTGTTGGGACTGTCGCAGATCTTGGCTTCT
TACAGTTCTTCCTGTCCAAACTCCATCCTGTCCCTCAGGAACGGGGGGAAAATTCTCCGAATGTTTTTGGTTTTTTGGCTGCTTGGAATT
TACTTCTGCCACCTGCTGGTCATCACTGTCCTCACTAAGTGGATTCTGGCTCCCCCGTACCTCATGGCTCAAACTACCACTCCTCAGTCG
CTATATTAAAGCTTATATTTTGCTGGATTACTGCTAAATACAAAAGAAAGTTCAATATGTTTTCATTTCTGTAGGGAAAATGGGATTGCT
GCTTTAAATTTCTGAGCTAGGGATTTTTTGGCAGCTGCAGTGTTGGCGACTATTGTAAAATTCTCTTTGTTTCTCTCTGTAAATAGCACC
TGCTAACATTACAATTTGTATTTATGTTTAAAGAAGGCATCATTTGGTGAACAGAACTAGGAAATGAATTTTTAGCTCTTAAAAGCATTT
GCTTTGAGACCGCACAGGAGTGTCTTTCCTTGTAAAACAGTGATGATAATTTCTGCCTTGGCCCTACCTTGAAGCAATGTTGTGTGAAGG
GATGAAGAATCTAAAAGTCTTCATAAGTCCTTGGGAGAGGTGCTAGAAAAATATAAGGCACTATCATAATTACAGTGATGTCCTTGCTGT

>99203_99203_1_WHSC1L1-FGFR1_WHSC1L1_chr8_38162104_ENST00000317025_FGFR1_chr8_38277253_ENST00000341462_length(amino acids)=915AA_BP=871
MDFSFSFMQGIMGNTIQQPPQLIDSANIRQEDAFDNNSDIAEDGGQTPYEATLQQGFQYPATTEDLPPLTNGYPSSISVYETQTKYQSYN
QYPNGSANGFGAVRNFSPTDYYHSEIPNTRPHEILEKPSPPQPPPPPSVPQTVIPKKTGSPEIKLKITKTIQNGRELFESSLCGDLLNEV
QASEHTKSKHESRKEKRKKSNKHDSSRSEERKSHKIPKLEPEEQNRPNERVDTVSEKPREEPVLKEEAPVQPILSSVPTTEVSTGVKFQV
GDLVWSKVGTYPWWPCMVSSDPQLEVHTKINTRGAREYHVQFFSNQPERAWVHEKRVREYKGHKQYEELLAEATKQASNHSEKQKIRKPR
PQRERAQWDIGIAHAEKALKMTREERIEQYTFIYIDKQPEEALSQAKKSVASKTEVKKTRRPRSVLNTQPEQTNAGEVASSLSSTEIRRH
SQRRHTSAEEEEPPPVKIAWKTAAARKSLPASITMHKGSLDLQKCNMSPVVKIEQVFALQNATGDGKFIDQFVYSTKGIGNKTEISVRGQ
DRLIISTPNQRNEKPTQSVSSPEATSGSTGSVEKKQQRRSIRTRSESEKSTEVVPKKKIKKEQVETVPQATVKTGLQKGASEISDSCKPL
KKRSRASTDVEMTSSAYRDTSDSDSRGLSDLQVGFGKQVDSPSATADADVSDVQSMDSSLSRRGTGMSKKDTVCQICESSGDSLIPCEGE
CCKHFHLECLGLASLPDSKFICMECKTGQHPCFSCKVSGKDVKRCSVGACGKFYHEACVRKFPTAIFESKGFRCPQHCCSACSMEKDIHK
ASKGRMMRCLRCPVAYHSGDACIAAGSMLVSSYILICSNHSKRSSNSSAVNVGFCFVCARAGREAGSDDLAPVPGDHHLLHRGLPHLLHG

--------------------------------------------------------------
>99203_99203_2_WHSC1L1-FGFR1_WHSC1L1_chr8_38162104_ENST00000433384_FGFR1_chr8_38277253_ENST00000341462_length(transcript)=6977nt_BP=3102nt
AGAGGCGGCGGCGGCGGCCAGCACGGAGGCGGAGGCCGAGGGGGCTGTGCACAGGTCGCCGCGGAGAGGCGTGCGAATTCCGAGCCGAGC
GCCGAGGACCGTGCTACCCAGGCCGGGCTGCCAGCCGCAGGCTCCTCTCTGGCAGCAGCGGCGGCGCGGCGACCCCCGTCCCTCGGCCTC
CCCTTCCCATCCCACCTCCCGAGCCTTCCTCTTCCCGCAGCACGCCCGGCCCGGCCCGGCCGTGGCCCTCCTCAGTGCCGGCCGCCATGG
CAGAGGCGTCCGGCGCGGGGAAAATCTAGCCCGGGGATTTCATGCGGCCTAGCTCGGTTCCGCCTCCTCCTCGCGCGGCCCCAGCGGCTG
CCCGCACCCCAGCCCCACTCCGGGCCTCCGTGTCTCTCCTGTGATCGCACTGACACGGCCGGGGGGTTAGAATGGAACAAACTGAAGGCC
CGATGAGAGAAAGGGAAAGTTAAGGATGCTGGAGCAGAACAATGGATTTCTCTTTCTCTTTCATGCAAGGGATCATGGGAAACACAATTC
AGCAACCACCTCAACTCATTGACTCCGCCAACATCCGTCAGGAGGATGCCTTTGATAACAACAGTGACATTGCTGAAGATGGTGGCCAGA
CACCATATGAAGCTACTTTGCAGCAAGGCTTTCAGTACCCAGCTACAACAGAAGATCTTCCTCCACTCACAAATGGGTATCCATCATCAA
TCAGTGTGTATGAAACTCAAACCAAATACCAGTCATATAATCAGTATCCTAATGGGTCAGCCAATGGCTTTGGTGCAGTTAGAAACTTTA
GCCCCACTGACTATTATCATTCAGAAATTCCAAACACAAGACCACATGAAATTCTGGAAAAACCTTCCCCTCCACAGCCACCACCTCCTC
CTTCGGTACCACAAACTGTGATTCCAAAGAAGACTGGCTCACCTGAAATTAAACTAAAAATAACCAAAACTATCCAGAATGGCAGGGAAT
TGTTTGAGTCTTCCCTTTGTGGAGACCTTTTAAATGAAGTACAGGCAAGTGAGCACACGAAATCAAAGCATGAAAGCAGAAAAGAAAAGA
GGAAAAAAAGCAACAAGCATGACTCATCAAGATCTGAAGAGCGCAAGTCACACAAAATCCCCAAATTAGAACCAGAGGAACAAAATAGAC
CAAATGAGAGGGTTGACACTGTATCAGAAAAACCAAGGGAAGAACCAGTACTAAAAGAGGAAGCCCCAGTTCAGCCAATACTATCTTCTG
TTCCAACAACGGAAGTGTCCACTGGTGTTAAGTTTCAGGTTGGCGATCTTGTGTGGTCCAAGGTGGGAACCTATCCTTGGTGGCCTTGTA
TGGTTTCAAGTGATCCCCAGCTTGAGGTTCATACTAAAATTAACACAAGAGGTGCCCGAGAATATCATGTCCAGTTTTTTAGCAACCAGC
CAGAGAGGGCGTGGGTTCATGAAAAACGGGTACGAGAGTATAAAGGTCATAAACAGTATGAAGAATTACTGGCTGAGGCAACCAAACAAG
CCAGCAATCACTCTGAGAAACAAAAGATTCGGAAACCCCGACCTCAGAGAGAACGTGCTCAGTGGGATATTGGCATTGCCCATGCAGAGA
AAGCATTGAAAATGACTCGAGAAGAAAGAATAGAACAGTATACTTTTATTTACATTGATAAACAGCCTGAAGAGGCTTTATCCCAAGCAA
AAAAGAGTGTTGCCTCCAAAACCGAAGTTAAAAAAACCCGACGACCAAGATCTGTGCTGAATACTCAGCCAGAACAGACCAATGCAGGGG
AGGTGGCCTCCTCACTCTCAAGTACTGAAATTCGGAGACATAGCCAGAGGCGGCACACAAGTGCGGAAGAGGAAGAGCCACCGCCTGTTA
AAATAGCCTGGAAAACTGCGGCAGCAAGGAAATCCTTACCAGCTTCCATTACGATGCACAAAGGGAGCCTGGATTTGCAGAAGTGTAACA
TGTCTCCAGTTGTGAAAATTGAACAAGTGTTTGCTCTTCAGAATGCTACAGGGGATGGGAAATTTATCGATCAATTTGTTTATTCAACAA
AGGGAATTGGTAACAAAACAGAAATAAGTGTCAGGGGGCAAGACAGGCTTATAATTTCTACACCAAACCAGAGAAATGAAAAGCCAACGC
AGAGTGTATCATCTCCTGAAGCAACATCTGGTTCTACAGGCTCAGTAGAAAAGAAGCAACAGAGAAGATCAATTAGAACTCGTTCTGAAT
CAGAGAAATCCACTGAGGTTGTGCCAAAGAAGAAGATCAAAAAGGAGCAGGTTGAAACAGTTCCTCAGGCTACAGTGAAGACTGGATTAC
AGAAAGGTGCCAGCGAGATTTCAGATTCCTGTAAACCTCTAAAGAAAAGGAGTCGCGCCTCAACTGATGTAGAAATGACTAGTTCAGCAT
ACAGAGACACATCTGACTCCGATTCTAGAGGACTGAGTGACCTGCAGGTAGGCTTTGGAAAGCAAGTAGATAGCCCTTCAGCTACTGCAG
ATGCAGACGTTTCTGATGTGCAGTCCATGGATTCAAGTTTGTCGAGAAGAGGCACTGGAATGAGTAAGAAGGACACTGTATGTCAGATTT
GTGAAAGCTCTGGTGACTCTCTGATTCCTTGTGAGGGAGAGTGCTGCAAACACTTTCACCTGGAGTGCCTGGGATTGGCATCACTTCCTG
ATAGCAAGTTCATCTGCATGGAATGTAAAACTGGGCAGCACCCATGTTTTTCGTGTAAAGTGTCTGGTAAAGATGTGAAGCGTTGTTCTG
TTGGTGCTTGTGGGAAATTTTATCATGAAGCCTGTGTCCGCAAATTCCCCACTGCCATCTTTGAATCAAAAGGATTCCGCTGTCCTCAGC
ACTGCTGCTCTGCCTGCTCTATGGAGAAAGATATCCACAAAGCAAGTAAAGGCCGCATGATGAGATGTTTAAGATGTCCAGTTGCCTATC
ACTCTGGAGATGCTTGCATTGCGGCCGGAAGCATGTTAGTATCCTCCTACATTCTCATCTGTAGTAATCATTCCAAACGGAGCAGTAATT
CTTCTGCTGTAAATGTAGGCTTTTGTTTCGTTTGTGCCAGAGCTGGAAGAGAGGCCGGCAGTGATGACCTCGCCCCTGTACCTGGAGATC
ATCATCTATTGCACAGGGGCCTTCCTCATCTCCTGCATGGTGGGGTCGGTCATCGTCTACAAGATGAAGAGTGGTACCAAGAAGAGTGAC
TTCCACAGCCAGATGGCTGTGCACAAGCTGGCCAAGAGCATCCCTCTGCGCAGACAGGTAACAGTGTCTGCTGACTCCAGTGCATCCATG
AACTCTGGGGTTCTTCTGGTTCGGCCATCACGGCTCTCCTCCAGTGGGACTCCCATGCTAGCAGGGGTCTCTGAGTATGAGCTTCCCGAA
GACCCTCGCTGGGAGCTGCCTCGGGACAGACTGGTCTTAGGCAAACCCCTGGGAGAGGGCTGCTTTGGGCAGGTGGTGTTGGCAGAGGCT
ATCGGGCTGGACAAGGACAAACCCAACCGTGTGACCAAAGTGGCTGTGAAGATGTTGAAGTCGGACGCAACAGAGAAAGACTTGTCAGAC
CTGATCTCAGAAATGGAGATGATGAAGATGATCGGGAAGCATAAGAATATCATCAACCTGCTGGGGGCCTGCACGCAGGATGGTCCCTTG
TATGTCATCGTGGAGTATGCCTCCAAGGGCAACCTGCGGGAGTACCTGCAGGCCCGGAGGCCCCCAGGGCTGGAATACTGCTACAACCCC
AGCCACAACCCAGAGGAGCAGCTCTCCTCCAAGGACCTGGTGTCCTGCGCCTACCAGGTGGCCCGAGGCATGGAGTATCTGGCCTCCAAG
AAGTGCATACACCGAGACCTGGCAGCCAGGAATGTCCTGGTGACAGAGGACAATGTGATGAAGATAGCAGACTTTGGCCTCGCACGGGAC
ATTCACCACATCGACTACTATAAAAAGACAACCAACGGCCGACTGCCTGTGAAGTGGATGGCACCCGAGGCATTATTTGACCGGATCTAC
ACCCACCAGAGTGATGTGTGGTCTTTCGGGGTGCTCCTGTGGGAGATCTTCACTCTGGGCGGCTCCCCATACCCCGGTGTGCCTGTGGAG
GAACTTTTCAAGCTGCTGAAGGAGGGTCACCGCATGGACAAGCCCAGTAACTGCACCAACGAGCTGTACATGATGATGCGGGACTGCTGG
CATGCAGTGCCCTCACAGAGACCCACCTTCAAGCAGCTGGTGGAAGACCTGGACCGCATCGTGGCCTTGACCTCCAACCAGGAGTACCTG
GACCTGTCCATGCCCCTGGACCAGTACTCCCCCAGCTTTCCCGACACCCGGAGCTCTACGTGCTCCTCAGGGGAGGATTCCGTCTTCTCT
CATGAGCCGCTGCCCGAGGAGCCCTGCCTGCCCCGACACCCAGCCCAGCTTGCCAATGGCGGACTCAAACGCCGCTGACTGCCACCCACA
CGCCCTCCCCAGACTCCACCGTCAGCTGTAACCCTCACCCACAGCCCCTGCTGGGCCCACCACCTGTCCGTCCCTGTCCCCTTTCCTGCT
GGCAGGAGCCGGCTGCCTACCAGGGGCCTTCCTGTGTGGCCTGCCTTCACCCCACTCAGCTCACCTCTCCCTCCACCTCCTCTCCACCTG
CTGGTGAGAGGTGCAAAGAGGCAGATCTTTGCTGCCAGCCACTTCATCCCCTCCCAGATGTTGGACCAACACCCCTCCCTGCCACCAGGC
ACTGCCTGGAGGGCAGGGAGTGGGAGCCAATGAACAGGCATGCAAGTGAGAGCTTCCTGAGCTTTCTCCTGTCGGTTTGGTCTGTTTTGC
CTTCACCCATAAGCCCCTCGCACTCTGGTGGCAGGTGCCTTGTCCTCAGGGCTACAGCAGTAGGGAGGTCAGTGCTTCGTGCCTCGATTG
AAGGTGACCTCTGCCCCAGATAGGTGGTGCCAGTGGCTTATTAATTCCGATACTAGTTTGCTTTGCTGACCAAATGCCTGGTACCAGAGG
ATGGTGAGGCGAAGGCCAGGTTGGGGGCAGTGTTGTGGCCCTGGGGCCCAGCCCCAAACTGGGGGCTCTGTATATAGCTATGAAGAAAAC
ACAAAGTGTATAAATCTGAGTATATATTTACATGTCTTTTTAAAAGGGTCGTTACCAGAGATTTACCCATCGGGTAAGATGCTCCTGGTG
GCTGGGAGGCATCAGTTGCTATATATTAAAAACAAAAAAGAAAAAAAAGGAAAATGTTTTTAAAAAGGTCATATATTTTTTGCTACTTTT
GCTGTTTTATTTTTTTAAATTATGTTCTAAACCTATTTTCAGTTTAGGTCCCTCAATAAAAATTGCTGCTGCTTCATTTATCTATGGGCT
GTATGAAAAGGGTGGGAATGTCCACTGGAAAGAAGGGACACCCACGGGCCCTGGGGCTAGGTCTGTCCCGAGGGCACCGCATGCTCCCGG
CGCAGGTTCCTTGTAACCTCTTCTTCCTAGGTCCTGCACCCAGACCTCACGACGCACCTCCTGCCTCTCCGCTGCTTTTGGAAAGTCAGA
AAAAGAAGATGTCTGCTTCGAGGGCAGGAACCCCATCCATGCAGTAGAGGCGCTGGGCAGAGAGTCAAGGCCCAGCAGCCATCGACCATG
GATGGTTTCCTCCAAGGAAACCGGTGGGGTTGGGCTGGGGAGGGGGCACCTACCTAGGAATAGCCACGGGGTAGAGCTACAGTGATTAAG
AGGAAAGCAAGGGCGCGGTTGCTCACGCCTGTAATCCCAGCACTTTGGGACACCGAGGTGGGCAGATCACTTCAGGTCAGGAGTTTGAGA
CCAGCCTGGCCAACTTAGTGAAACCCCATCTCTACTAAAAATGCAAAAATTATCCAGGCATGGTGGCACACGCCTGTAATCCCAGCTCCA
CAGGAGGCTGAGGCAGAATCCCTTGAAGCTGGGAGGCGGAGGTTGCAGTGAGCCGAGATTGCGCCATTGCACTCCAGCCTGGGCAACAGA
GAAAACAAAAAGGAAAACAAATGATGAAGGTCTGCAGAAACTGAAACCCAGACATGTGTCTGCCCCCTCTATGTGGGCATGGTTTTGCCA
GTGCTTCTAAGTGCAGGAGAACATGTCACCTGAGGCTAGTTTTGCATTCAGGTCCCTGGCTTCGTTTCTTGTTGGTATGCCTCCCCAGAT
CGTCCTTCCTGTATCCATGTGACCAGACTGTATTTGTTGGGACTGTCGCAGATCTTGGCTTCTTACAGTTCTTCCTGTCCAAACTCCATC
CTGTCCCTCAGGAACGGGGGGAAAATTCTCCGAATGTTTTTGGTTTTTTGGCTGCTTGGAATTTACTTCTGCCACCTGCTGGTCATCACT
GTCCTCACTAAGTGGATTCTGGCTCCCCCGTACCTCATGGCTCAAACTACCACTCCTCAGTCGCTATATTAAAGCTTATATTTTGCTGGA
TTACTGCTAAATACAAAAGAAAGTTCAATATGTTTTCATTTCTGTAGGGAAAATGGGATTGCTGCTTTAAATTTCTGAGCTAGGGATTTT
TTGGCAGCTGCAGTGTTGGCGACTATTGTAAAATTCTCTTTGTTTCTCTCTGTAAATAGCACCTGCTAACATTACAATTTGTATTTATGT
TTAAAGAAGGCATCATTTGGTGAACAGAACTAGGAAATGAATTTTTAGCTCTTAAAAGCATTTGCTTTGAGACCGCACAGGAGTGTCTTT
CCTTGTAAAACAGTGATGATAATTTCTGCCTTGGCCCTACCTTGAAGCAATGTTGTGTGAAGGGATGAAGAATCTAAAAGTCTTCATAAG
TCCTTGGGAGAGGTGCTAGAAAAATATAAGGCACTATCATAATTACAGTGATGTCCTTGCTGTTACTACTCAAATCACCCACAAATTTCC

>99203_99203_2_WHSC1L1-FGFR1_WHSC1L1_chr8_38162104_ENST00000433384_FGFR1_chr8_38277253_ENST00000341462_length(amino acids)=915AA_BP=871
MDFSFSFMQGIMGNTIQQPPQLIDSANIRQEDAFDNNSDIAEDGGQTPYEATLQQGFQYPATTEDLPPLTNGYPSSISVYETQTKYQSYN
QYPNGSANGFGAVRNFSPTDYYHSEIPNTRPHEILEKPSPPQPPPPPSVPQTVIPKKTGSPEIKLKITKTIQNGRELFESSLCGDLLNEV
QASEHTKSKHESRKEKRKKSNKHDSSRSEERKSHKIPKLEPEEQNRPNERVDTVSEKPREEPVLKEEAPVQPILSSVPTTEVSTGVKFQV
GDLVWSKVGTYPWWPCMVSSDPQLEVHTKINTRGAREYHVQFFSNQPERAWVHEKRVREYKGHKQYEELLAEATKQASNHSEKQKIRKPR
PQRERAQWDIGIAHAEKALKMTREERIEQYTFIYIDKQPEEALSQAKKSVASKTEVKKTRRPRSVLNTQPEQTNAGEVASSLSSTEIRRH
SQRRHTSAEEEEPPPVKIAWKTAAARKSLPASITMHKGSLDLQKCNMSPVVKIEQVFALQNATGDGKFIDQFVYSTKGIGNKTEISVRGQ
DRLIISTPNQRNEKPTQSVSSPEATSGSTGSVEKKQQRRSIRTRSESEKSTEVVPKKKIKKEQVETVPQATVKTGLQKGASEISDSCKPL
KKRSRASTDVEMTSSAYRDTSDSDSRGLSDLQVGFGKQVDSPSATADADVSDVQSMDSSLSRRGTGMSKKDTVCQICESSGDSLIPCEGE
CCKHFHLECLGLASLPDSKFICMECKTGQHPCFSCKVSGKDVKRCSVGACGKFYHEACVRKFPTAIFESKGFRCPQHCCSACSMEKDIHK
ASKGRMMRCLRCPVAYHSGDACIAAGSMLVSSYILICSNHSKRSSNSSAVNVGFCFVCARAGREAGSDDLAPVPGDHHLLHRGLPHLLHG

--------------------------------------------------------------
>99203_99203_3_WHSC1L1-FGFR1_WHSC1L1_chr8_38162104_ENST00000527502_FGFR1_chr8_38277253_ENST00000341462_length(transcript)=6578nt_BP=2703nt
TGTGATCGCACTGACACGGCCGGGGGGTTAGAATGGAACAAACTGAAGGCCCGATGAGAGAAAGGGAAAGTTAAGGATGCTGGAGCAGAA
CAATGGATTTCTCTTTCTCTTTCATGCAAGGGATCATGGGAAACACAATTCAGCAACCACCTCAACTCATTGACTCCGCCAACATCCGTC
AGGAGGATGCCTTTGATAACAACAGTGACATTGCTGAAGATGGTGGCCAGACACCATATGAAGCTACTTTGCAGCAAGGCTTTCAGTACC
CAGCTACAACAGAAGATCTTCCTCCACTCACAAATGGGTATCCATCATCAATCAGTGTGTATGAAACTCAAACCAAATACCAGTCATATA
ATCAGTATCCTAATGGGTCAGCCAATGGCTTTGGTGCAGTTAGAAACTTTAGCCCCACTGACTATTATCATTCAGAAATTCCAAACACAA
GACCACATGAAATTCTGGAAAAACCTTCCCCTCCACAGCCACCACCTCCTCCTTCGGTACCACAAACTGTGATTCCAAAGAAGACTGGCT
CACCTGAAATTAAACTAAAAATAACCAAAACTATCCAGAATGGCAGGGAATTGTTTGAGTCTTCCCTTTGTGGAGACCTTTTAAATGAAG
TACAGGCAAGTGAGCACACGAAATCAAAGCATGAAAGCAGAAAAGAAAAGAGGAAAAAAAGCAACAAGCATGACTCATCAAGATCTGAAG
AGCGCAAGTCACACAAAATCCCCAAATTAGAACCAGAGGAACAAAATAGACCAAATGAGAGGGTTGACACTGTATCAGAAAAACCAAGGG
AAGAACCAGTACTAAAAGAGGAAGCCCCAGTTCAGCCAATACTATCTTCTGTTCCAACAACGGAAGTGTCCACTGGTGTTAAGTTTCAGG
TTGGCGATCTTGTGTGGTCCAAGGTGGGAACCTATCCTTGGTGGCCTTGTATGGTTTCAAGTGATCCCCAGCTTGAGGTTCATACTAAAA
TTAACACAAGAGGTGCCCGAGAATATCATGTCCAGTTTTTTAGCAACCAGCCAGAGAGGGCGTGGGTTCATGAAAAACGGGTACGAGAGT
ATAAAGGTCATAAACAGTATGAAGAATTACTGGCTGAGGCAACCAAACAAGCCAGCAATCACTCTGAGAAACAAAAGATTCGGAAACCCC
GACCTCAGAGAGAACGTGCTCAGTGGGATATTGGCATTGCCCATGCAGAGAAAGCATTGAAAATGACTCGAGAAGAAAGAATAGAACAGT
ATACTTTTATTTACATTGATAAACAGCCTGAAGAGGCTTTATCCCAAGCAAAAAAGAGTGTTGCCTCCAAAACCGAAGTTAAAAAAACCC
GACGACCAAGATCTGTGCTGAATACTCAGCCAGAACAGACCAATGCAGGGGAGGTGGCCTCCTCACTCTCAAGTACTGAAATTCGGAGAC
ATAGCCAGAGGCGGCACACAAGTGCGGAAGAGGAAGAGCCACCGCCTGTTAAAATAGCCTGGAAAACTGCGGCAGCAAGGAAATCCTTAC
CAGCTTCCATTACGATGCACAAAGGGAGCCTGGATTTGCAGAAGTGTAACATGTCTCCAGTTGTGAAAATTGAACAAGTGTTTGCTCTTC
AGAATGCTACAGGGGATGGGAAATTTATCGATCAATTTGTTTATTCAACAAAGGGAATTGGTAACAAAACAGAAATAAGTGTCAGGGGGC
AAGACAGGCTTATAATTTCTACACCAAACCAGAGAAATGAAAAGCCAACGCAGAGTGTATCATCTCCTGAAGCAACATCTGGTTCTACAG
GCTCAGTAGAAAAGAAGCAACAGAGAAGATCAATTAGAACTCGTTCTGAATCAGAGAAATCCACTGAGGTTGTGCCAAAGAAGAAGATCA
AAAAGGAGCAGGTTGAAACAGTTCCTCAGGCTACAGTGAAGACTGGATTACAGAAAGGTGCCAGCGAGATTTCAGATTCCTGTAAACCTC
TAAAGAAAAGGAGTCGCGCCTCAACTGATGTAGAAATGACTAGTTCAGCATACAGAGACACATCTGACTCCGATTCTAGAGGACTGAGTG
ACCTGCAGGTAGGCTTTGGAAAGCAAGTAGATAGCCCTTCAGCTACTGCAGATGCAGACGTTTCTGATGTGCAGTCCATGGATTCAAGTT
TGTCGAGAAGAGGCACTGGAATGAGTAAGAAGGACACTGTATGTCAGATTTGTGAAAGCTCTGGTGACTCTCTGATTCCTTGTGAGGGAG
AGTGCTGCAAACACTTTCACCTGGAGTGCCTGGGATTGGCATCACTTCCTGATAGCAAGTTCATCTGCATGGAATGTAAAACTGGGCAGC
ACCCATGTTTTTCGTGTAAAGTGTCTGGTAAAGATGTGAAGCGTTGTTCTGTTGGTGCTTGTGGGAAATTTTATCATGAAGCCTGTGTCC
GCAAATTCCCCACTGCCATCTTTGAATCAAAAGGATTCCGCTGTCCTCAGCACTGCTGCTCTGCCTGCTCTATGGAGAAAGATATCCACA
AAGCAAGTAAAGGCCGCATGATGAGATGTTTAAGATGTCCAGTTGCCTATCACTCTGGAGATGCTTGCATTGCGGCCGGAAGCATGTTAG
TATCCTCCTACATTCTCATCTGTAGTAATCATTCCAAACGGAGCAGTAATTCTTCTGCTGTAAATGTAGGCTTTTGTTTCGTTTGTGCCA
GAGCTGGAAGAGAGGCCGGCAGTGATGACCTCGCCCCTGTACCTGGAGATCATCATCTATTGCACAGGGGCCTTCCTCATCTCCTGCATG
GTGGGGTCGGTCATCGTCTACAAGATGAAGAGTGGTACCAAGAAGAGTGACTTCCACAGCCAGATGGCTGTGCACAAGCTGGCCAAGAGC
ATCCCTCTGCGCAGACAGGTAACAGTGTCTGCTGACTCCAGTGCATCCATGAACTCTGGGGTTCTTCTGGTTCGGCCATCACGGCTCTCC
TCCAGTGGGACTCCCATGCTAGCAGGGGTCTCTGAGTATGAGCTTCCCGAAGACCCTCGCTGGGAGCTGCCTCGGGACAGACTGGTCTTA
GGCAAACCCCTGGGAGAGGGCTGCTTTGGGCAGGTGGTGTTGGCAGAGGCTATCGGGCTGGACAAGGACAAACCCAACCGTGTGACCAAA
GTGGCTGTGAAGATGTTGAAGTCGGACGCAACAGAGAAAGACTTGTCAGACCTGATCTCAGAAATGGAGATGATGAAGATGATCGGGAAG
CATAAGAATATCATCAACCTGCTGGGGGCCTGCACGCAGGATGGTCCCTTGTATGTCATCGTGGAGTATGCCTCCAAGGGCAACCTGCGG
GAGTACCTGCAGGCCCGGAGGCCCCCAGGGCTGGAATACTGCTACAACCCCAGCCACAACCCAGAGGAGCAGCTCTCCTCCAAGGACCTG
GTGTCCTGCGCCTACCAGGTGGCCCGAGGCATGGAGTATCTGGCCTCCAAGAAGTGCATACACCGAGACCTGGCAGCCAGGAATGTCCTG
GTGACAGAGGACAATGTGATGAAGATAGCAGACTTTGGCCTCGCACGGGACATTCACCACATCGACTACTATAAAAAGACAACCAACGGC
CGACTGCCTGTGAAGTGGATGGCACCCGAGGCATTATTTGACCGGATCTACACCCACCAGAGTGATGTGTGGTCTTTCGGGGTGCTCCTG
TGGGAGATCTTCACTCTGGGCGGCTCCCCATACCCCGGTGTGCCTGTGGAGGAACTTTTCAAGCTGCTGAAGGAGGGTCACCGCATGGAC
AAGCCCAGTAACTGCACCAACGAGCTGTACATGATGATGCGGGACTGCTGGCATGCAGTGCCCTCACAGAGACCCACCTTCAAGCAGCTG
GTGGAAGACCTGGACCGCATCGTGGCCTTGACCTCCAACCAGGAGTACCTGGACCTGTCCATGCCCCTGGACCAGTACTCCCCCAGCTTT
CCCGACACCCGGAGCTCTACGTGCTCCTCAGGGGAGGATTCCGTCTTCTCTCATGAGCCGCTGCCCGAGGAGCCCTGCCTGCCCCGACAC
CCAGCCCAGCTTGCCAATGGCGGACTCAAACGCCGCTGACTGCCACCCACACGCCCTCCCCAGACTCCACCGTCAGCTGTAACCCTCACC
CACAGCCCCTGCTGGGCCCACCACCTGTCCGTCCCTGTCCCCTTTCCTGCTGGCAGGAGCCGGCTGCCTACCAGGGGCCTTCCTGTGTGG
CCTGCCTTCACCCCACTCAGCTCACCTCTCCCTCCACCTCCTCTCCACCTGCTGGTGAGAGGTGCAAAGAGGCAGATCTTTGCTGCCAGC
CACTTCATCCCCTCCCAGATGTTGGACCAACACCCCTCCCTGCCACCAGGCACTGCCTGGAGGGCAGGGAGTGGGAGCCAATGAACAGGC
ATGCAAGTGAGAGCTTCCTGAGCTTTCTCCTGTCGGTTTGGTCTGTTTTGCCTTCACCCATAAGCCCCTCGCACTCTGGTGGCAGGTGCC
TTGTCCTCAGGGCTACAGCAGTAGGGAGGTCAGTGCTTCGTGCCTCGATTGAAGGTGACCTCTGCCCCAGATAGGTGGTGCCAGTGGCTT
ATTAATTCCGATACTAGTTTGCTTTGCTGACCAAATGCCTGGTACCAGAGGATGGTGAGGCGAAGGCCAGGTTGGGGGCAGTGTTGTGGC
CCTGGGGCCCAGCCCCAAACTGGGGGCTCTGTATATAGCTATGAAGAAAACACAAAGTGTATAAATCTGAGTATATATTTACATGTCTTT
TTAAAAGGGTCGTTACCAGAGATTTACCCATCGGGTAAGATGCTCCTGGTGGCTGGGAGGCATCAGTTGCTATATATTAAAAACAAAAAA
GAAAAAAAAGGAAAATGTTTTTAAAAAGGTCATATATTTTTTGCTACTTTTGCTGTTTTATTTTTTTAAATTATGTTCTAAACCTATTTT
CAGTTTAGGTCCCTCAATAAAAATTGCTGCTGCTTCATTTATCTATGGGCTGTATGAAAAGGGTGGGAATGTCCACTGGAAAGAAGGGAC
ACCCACGGGCCCTGGGGCTAGGTCTGTCCCGAGGGCACCGCATGCTCCCGGCGCAGGTTCCTTGTAACCTCTTCTTCCTAGGTCCTGCAC
CCAGACCTCACGACGCACCTCCTGCCTCTCCGCTGCTTTTGGAAAGTCAGAAAAAGAAGATGTCTGCTTCGAGGGCAGGAACCCCATCCA
TGCAGTAGAGGCGCTGGGCAGAGAGTCAAGGCCCAGCAGCCATCGACCATGGATGGTTTCCTCCAAGGAAACCGGTGGGGTTGGGCTGGG
GAGGGGGCACCTACCTAGGAATAGCCACGGGGTAGAGCTACAGTGATTAAGAGGAAAGCAAGGGCGCGGTTGCTCACGCCTGTAATCCCA
GCACTTTGGGACACCGAGGTGGGCAGATCACTTCAGGTCAGGAGTTTGAGACCAGCCTGGCCAACTTAGTGAAACCCCATCTCTACTAAA
AATGCAAAAATTATCCAGGCATGGTGGCACACGCCTGTAATCCCAGCTCCACAGGAGGCTGAGGCAGAATCCCTTGAAGCTGGGAGGCGG
AGGTTGCAGTGAGCCGAGATTGCGCCATTGCACTCCAGCCTGGGCAACAGAGAAAACAAAAAGGAAAACAAATGATGAAGGTCTGCAGAA
ACTGAAACCCAGACATGTGTCTGCCCCCTCTATGTGGGCATGGTTTTGCCAGTGCTTCTAAGTGCAGGAGAACATGTCACCTGAGGCTAG
TTTTGCATTCAGGTCCCTGGCTTCGTTTCTTGTTGGTATGCCTCCCCAGATCGTCCTTCCTGTATCCATGTGACCAGACTGTATTTGTTG
GGACTGTCGCAGATCTTGGCTTCTTACAGTTCTTCCTGTCCAAACTCCATCCTGTCCCTCAGGAACGGGGGGAAAATTCTCCGAATGTTT
TTGGTTTTTTGGCTGCTTGGAATTTACTTCTGCCACCTGCTGGTCATCACTGTCCTCACTAAGTGGATTCTGGCTCCCCCGTACCTCATG
GCTCAAACTACCACTCCTCAGTCGCTATATTAAAGCTTATATTTTGCTGGATTACTGCTAAATACAAAAGAAAGTTCAATATGTTTTCAT
TTCTGTAGGGAAAATGGGATTGCTGCTTTAAATTTCTGAGCTAGGGATTTTTTGGCAGCTGCAGTGTTGGCGACTATTGTAAAATTCTCT
TTGTTTCTCTCTGTAAATAGCACCTGCTAACATTACAATTTGTATTTATGTTTAAAGAAGGCATCATTTGGTGAACAGAACTAGGAAATG
AATTTTTAGCTCTTAAAAGCATTTGCTTTGAGACCGCACAGGAGTGTCTTTCCTTGTAAAACAGTGATGATAATTTCTGCCTTGGCCCTA
CCTTGAAGCAATGTTGTGTGAAGGGATGAAGAATCTAAAAGTCTTCATAAGTCCTTGGGAGAGGTGCTAGAAAAATATAAGGCACTATCA
TAATTACAGTGATGTCCTTGCTGTTACTACTCAAATCACCCACAAATTTCCCCAAAGACTGCGCTAGCTGTCAAATAAAAGACAGTGAAA

>99203_99203_3_WHSC1L1-FGFR1_WHSC1L1_chr8_38162104_ENST00000527502_FGFR1_chr8_38277253_ENST00000341462_length(amino acids)=915AA_BP=871
MDFSFSFMQGIMGNTIQQPPQLIDSANIRQEDAFDNNSDIAEDGGQTPYEATLQQGFQYPATTEDLPPLTNGYPSSISVYETQTKYQSYN
QYPNGSANGFGAVRNFSPTDYYHSEIPNTRPHEILEKPSPPQPPPPPSVPQTVIPKKTGSPEIKLKITKTIQNGRELFESSLCGDLLNEV
QASEHTKSKHESRKEKRKKSNKHDSSRSEERKSHKIPKLEPEEQNRPNERVDTVSEKPREEPVLKEEAPVQPILSSVPTTEVSTGVKFQV
GDLVWSKVGTYPWWPCMVSSDPQLEVHTKINTRGAREYHVQFFSNQPERAWVHEKRVREYKGHKQYEELLAEATKQASNHSEKQKIRKPR
PQRERAQWDIGIAHAEKALKMTREERIEQYTFIYIDKQPEEALSQAKKSVASKTEVKKTRRPRSVLNTQPEQTNAGEVASSLSSTEIRRH
SQRRHTSAEEEEPPPVKIAWKTAAARKSLPASITMHKGSLDLQKCNMSPVVKIEQVFALQNATGDGKFIDQFVYSTKGIGNKTEISVRGQ
DRLIISTPNQRNEKPTQSVSSPEATSGSTGSVEKKQQRRSIRTRSESEKSTEVVPKKKIKKEQVETVPQATVKTGLQKGASEISDSCKPL
KKRSRASTDVEMTSSAYRDTSDSDSRGLSDLQVGFGKQVDSPSATADADVSDVQSMDSSLSRRGTGMSKKDTVCQICESSGDSLIPCEGE
CCKHFHLECLGLASLPDSKFICMECKTGQHPCFSCKVSGKDVKRCSVGACGKFYHEACVRKFPTAIFESKGFRCPQHCCSACSMEKDIHK
ASKGRMMRCLRCPVAYHSGDACIAAGSMLVSSYILICSNHSKRSSNSSAVNVGFCFVCARAGREAGSDDLAPVPGDHHLLHRGLPHLLHG

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Fusion Gene PPI Analysis for WHSC1L1-FGFR1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for WHSC1L1-FGFR1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for WHSC1L1-FGFR1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource