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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:WNK1-IQSEC3 (FusionGDB2 ID:99331)

Fusion Gene Summary for WNK1-IQSEC3

Fusion gene summary

Fusion gene information	Fusion gene name: WNK1-IQSEC3
	Fusion gene ID: 99331
		Hgene	Tgene
	Gene symbol	WNK1	IQSEC3
	Gene ID	65125	440073
	Gene name	WNK lysine deficient protein kinase 1	IQ motif and Sec7 domain ArfGEF 3
	Synonyms	HSAN2\|HSN2\|KDP\|PPP1R167\|PRKWNK1\|PSK\|p65	-
	Cytomap	12p13.33	12p13.33
	Type of gene	protein-coding	protein-coding
	Description	serine/threonine-protein kinase WNK1WNK lysine deficient protein kinase 1 isoformerythrocyte 65 kDa proteinprostate-derived sterile 20-like kinaseprotein kinase with no lysine 1protein phosphatase 1, regulatory subunit 167serine/threonine-protein ki	IQ motif and SEC7 domain-containing protein 3IQ motif and Sec7 domain 3
	Modification date	20200327	20200313
	UniProtAcc	.	Q9UPP2
	Ensembl transtripts involved in fusion gene	ENST00000315939, ENST00000447667, ENST00000530271, ENST00000535572, ENST00000537687, ENST00000340908, ENST00000540360, ENST00000574564,	ENST00000382841, ENST00000537151, ENST00000326261, ENST00000538872,
Fusion gene scores	* DoF score	23 X 19 X 15=6555	4 X 7 X 4=112
	# samples	37	5
	** MAII score	log2(37/6555*10)=-4.14699860459281 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(5/112*10)=-1.16349873228288 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: WNK1 [Title/Abstract] AND IQSEC3 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	WNK1(863490)-IQSEC3(247433), # samples:3
Anticipated loss of major functional domain due to fusion event.	WNK1-IQSEC3 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF. WNK1-IQSEC3 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF. WNK1-IQSEC3 seems lost the major protein functional domain in Hgene partner, which is a kinase due to the frame-shifted ORF. WNK1-IQSEC3 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	WNK1	GO:0006468	protein phosphorylation	10660600
Hgene	WNK1	GO:0010923	negative regulation of phosphatase activity	19389623
Hgene	WNK1	GO:0023016	signal transduction by trans-phosphorylation	16669787
Hgene	WNK1	GO:0035556	intracellular signal transduction	10660600

Fusion gene breakpoints across WNK1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across IQSEC3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	OV	TCGA-24-0970-01B	WNK1	chr12	863490	+	IQSEC3	chr12	234799	+
ChimerDB4	OV	TCGA-24-0970-01B	WNK1	chr12	863490	-	IQSEC3	chr12	247433	+
ChimerDB4	OV	TCGA-24-0970-01B	WNK1	chr12	863490	+	IQSEC3	chr12	247433	+
ChimerDB4	OV	TCGA-24-0970	WNK1	chr12	863490	+	IQSEC3	chr12	247432	+

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Fusion Gene ORF analysis for WNK1-IQSEC3

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-5UTR	ENST00000315939	ENST00000382841	WNK1	chr12	863490	+	IQSEC3	chr12	247433	+
5CDS-5UTR	ENST00000315939	ENST00000382841	WNK1	chr12	863490	+	IQSEC3	chr12	247432	+
5CDS-5UTR	ENST00000447667	ENST00000382841	WNK1	chr12	863490	+	IQSEC3	chr12	247433	+
5CDS-5UTR	ENST00000447667	ENST00000382841	WNK1	chr12	863490	+	IQSEC3	chr12	247432	+
5CDS-5UTR	ENST00000530271	ENST00000382841	WNK1	chr12	863490	+	IQSEC3	chr12	247433	+
5CDS-5UTR	ENST00000530271	ENST00000382841	WNK1	chr12	863490	+	IQSEC3	chr12	247432	+
5CDS-5UTR	ENST00000535572	ENST00000382841	WNK1	chr12	863490	+	IQSEC3	chr12	247433	+
5CDS-5UTR	ENST00000535572	ENST00000382841	WNK1	chr12	863490	+	IQSEC3	chr12	247432	+
5CDS-5UTR	ENST00000537687	ENST00000382841	WNK1	chr12	863490	+	IQSEC3	chr12	247433	+
5CDS-5UTR	ENST00000537687	ENST00000382841	WNK1	chr12	863490	+	IQSEC3	chr12	247432	+
5CDS-intron	ENST00000315939	ENST00000382841	WNK1	chr12	863490	+	IQSEC3	chr12	234799	+
5CDS-intron	ENST00000315939	ENST00000537151	WNK1	chr12	863490	+	IQSEC3	chr12	234799	+
5CDS-intron	ENST00000315939	ENST00000537151	WNK1	chr12	863490	+	IQSEC3	chr12	247433	+
5CDS-intron	ENST00000315939	ENST00000537151	WNK1	chr12	863490	+	IQSEC3	chr12	247432	+
5CDS-intron	ENST00000447667	ENST00000382841	WNK1	chr12	863490	+	IQSEC3	chr12	234799	+
5CDS-intron	ENST00000447667	ENST00000537151	WNK1	chr12	863490	+	IQSEC3	chr12	234799	+
5CDS-intron	ENST00000447667	ENST00000537151	WNK1	chr12	863490	+	IQSEC3	chr12	247433	+
5CDS-intron	ENST00000447667	ENST00000537151	WNK1	chr12	863490	+	IQSEC3	chr12	247432	+
5CDS-intron	ENST00000530271	ENST00000382841	WNK1	chr12	863490	+	IQSEC3	chr12	234799	+
5CDS-intron	ENST00000530271	ENST00000537151	WNK1	chr12	863490	+	IQSEC3	chr12	234799	+
5CDS-intron	ENST00000530271	ENST00000537151	WNK1	chr12	863490	+	IQSEC3	chr12	247433	+
5CDS-intron	ENST00000530271	ENST00000537151	WNK1	chr12	863490	+	IQSEC3	chr12	247432	+
5CDS-intron	ENST00000535572	ENST00000382841	WNK1	chr12	863490	+	IQSEC3	chr12	234799	+
5CDS-intron	ENST00000535572	ENST00000537151	WNK1	chr12	863490	+	IQSEC3	chr12	234799	+
5CDS-intron	ENST00000535572	ENST00000537151	WNK1	chr12	863490	+	IQSEC3	chr12	247433	+
5CDS-intron	ENST00000535572	ENST00000537151	WNK1	chr12	863490	+	IQSEC3	chr12	247432	+
5CDS-intron	ENST00000537687	ENST00000382841	WNK1	chr12	863490	+	IQSEC3	chr12	234799	+
5CDS-intron	ENST00000537687	ENST00000537151	WNK1	chr12	863490	+	IQSEC3	chr12	234799	+
5CDS-intron	ENST00000537687	ENST00000537151	WNK1	chr12	863490	+	IQSEC3	chr12	247433	+
5CDS-intron	ENST00000537687	ENST00000537151	WNK1	chr12	863490	+	IQSEC3	chr12	247432	+
Frame-shift	ENST00000315939	ENST00000326261	WNK1	chr12	863490	+	IQSEC3	chr12	234799	+
Frame-shift	ENST00000315939	ENST00000538872	WNK1	chr12	863490	+	IQSEC3	chr12	234799	+
Frame-shift	ENST00000447667	ENST00000326261	WNK1	chr12	863490	+	IQSEC3	chr12	234799	+
Frame-shift	ENST00000447667	ENST00000538872	WNK1	chr12	863490	+	IQSEC3	chr12	234799	+
Frame-shift	ENST00000530271	ENST00000326261	WNK1	chr12	863490	+	IQSEC3	chr12	234799	+
Frame-shift	ENST00000530271	ENST00000538872	WNK1	chr12	863490	+	IQSEC3	chr12	234799	+
Frame-shift	ENST00000535572	ENST00000326261	WNK1	chr12	863490	+	IQSEC3	chr12	234799	+
Frame-shift	ENST00000535572	ENST00000538872	WNK1	chr12	863490	+	IQSEC3	chr12	234799	+
Frame-shift	ENST00000537687	ENST00000326261	WNK1	chr12	863490	+	IQSEC3	chr12	234799	+
Frame-shift	ENST00000537687	ENST00000538872	WNK1	chr12	863490	+	IQSEC3	chr12	234799	+
In-frame	ENST00000315939	ENST00000326261	WNK1	chr12	863490	+	IQSEC3	chr12	247433	+
In-frame	ENST00000315939	ENST00000326261	WNK1	chr12	863490	+	IQSEC3	chr12	247432	+
In-frame	ENST00000315939	ENST00000538872	WNK1	chr12	863490	+	IQSEC3	chr12	247433	+
In-frame	ENST00000315939	ENST00000538872	WNK1	chr12	863490	+	IQSEC3	chr12	247432	+
In-frame	ENST00000447667	ENST00000326261	WNK1	chr12	863490	+	IQSEC3	chr12	247433	+
In-frame	ENST00000447667	ENST00000326261	WNK1	chr12	863490	+	IQSEC3	chr12	247432	+
In-frame	ENST00000447667	ENST00000538872	WNK1	chr12	863490	+	IQSEC3	chr12	247433	+
In-frame	ENST00000447667	ENST00000538872	WNK1	chr12	863490	+	IQSEC3	chr12	247432	+
In-frame	ENST00000530271	ENST00000326261	WNK1	chr12	863490	+	IQSEC3	chr12	247433	+
In-frame	ENST00000530271	ENST00000326261	WNK1	chr12	863490	+	IQSEC3	chr12	247432	+
In-frame	ENST00000530271	ENST00000538872	WNK1	chr12	863490	+	IQSEC3	chr12	247433	+
In-frame	ENST00000530271	ENST00000538872	WNK1	chr12	863490	+	IQSEC3	chr12	247432	+
In-frame	ENST00000535572	ENST00000326261	WNK1	chr12	863490	+	IQSEC3	chr12	247433	+
In-frame	ENST00000535572	ENST00000326261	WNK1	chr12	863490	+	IQSEC3	chr12	247432	+
In-frame	ENST00000535572	ENST00000538872	WNK1	chr12	863490	+	IQSEC3	chr12	247433	+
In-frame	ENST00000535572	ENST00000538872	WNK1	chr12	863490	+	IQSEC3	chr12	247432	+
In-frame	ENST00000537687	ENST00000326261	WNK1	chr12	863490	+	IQSEC3	chr12	247433	+
In-frame	ENST00000537687	ENST00000326261	WNK1	chr12	863490	+	IQSEC3	chr12	247432	+
In-frame	ENST00000537687	ENST00000538872	WNK1	chr12	863490	+	IQSEC3	chr12	247433	+
In-frame	ENST00000537687	ENST00000538872	WNK1	chr12	863490	+	IQSEC3	chr12	247432	+
intron-3CDS	ENST00000340908	ENST00000326261	WNK1	chr12	863490	+	IQSEC3	chr12	234799	+
intron-3CDS	ENST00000340908	ENST00000326261	WNK1	chr12	863490	+	IQSEC3	chr12	247433	+
intron-3CDS	ENST00000340908	ENST00000326261	WNK1	chr12	863490	+	IQSEC3	chr12	247432	+
intron-3CDS	ENST00000340908	ENST00000538872	WNK1	chr12	863490	+	IQSEC3	chr12	234799	+
intron-3CDS	ENST00000340908	ENST00000538872	WNK1	chr12	863490	+	IQSEC3	chr12	247433	+
intron-3CDS	ENST00000340908	ENST00000538872	WNK1	chr12	863490	+	IQSEC3	chr12	247432	+
intron-3CDS	ENST00000540360	ENST00000326261	WNK1	chr12	863490	+	IQSEC3	chr12	234799	+
intron-3CDS	ENST00000540360	ENST00000326261	WNK1	chr12	863490	+	IQSEC3	chr12	247433	+
intron-3CDS	ENST00000540360	ENST00000326261	WNK1	chr12	863490	+	IQSEC3	chr12	247432	+
intron-3CDS	ENST00000540360	ENST00000538872	WNK1	chr12	863490	+	IQSEC3	chr12	234799	+
intron-3CDS	ENST00000540360	ENST00000538872	WNK1	chr12	863490	+	IQSEC3	chr12	247433	+
intron-3CDS	ENST00000540360	ENST00000538872	WNK1	chr12	863490	+	IQSEC3	chr12	247432	+
intron-3CDS	ENST00000574564	ENST00000326261	WNK1	chr12	863490	+	IQSEC3	chr12	234799	+
intron-3CDS	ENST00000574564	ENST00000326261	WNK1	chr12	863490	+	IQSEC3	chr12	247433	+
intron-3CDS	ENST00000574564	ENST00000326261	WNK1	chr12	863490	+	IQSEC3	chr12	247432	+
intron-3CDS	ENST00000574564	ENST00000538872	WNK1	chr12	863490	+	IQSEC3	chr12	234799	+
intron-3CDS	ENST00000574564	ENST00000538872	WNK1	chr12	863490	+	IQSEC3	chr12	247433	+
intron-3CDS	ENST00000574564	ENST00000538872	WNK1	chr12	863490	+	IQSEC3	chr12	247432	+
intron-5UTR	ENST00000340908	ENST00000382841	WNK1	chr12	863490	+	IQSEC3	chr12	247433	+
intron-5UTR	ENST00000340908	ENST00000382841	WNK1	chr12	863490	+	IQSEC3	chr12	247432	+
intron-5UTR	ENST00000540360	ENST00000382841	WNK1	chr12	863490	+	IQSEC3	chr12	247433	+
intron-5UTR	ENST00000540360	ENST00000382841	WNK1	chr12	863490	+	IQSEC3	chr12	247432	+
intron-5UTR	ENST00000574564	ENST00000382841	WNK1	chr12	863490	+	IQSEC3	chr12	247433	+
intron-5UTR	ENST00000574564	ENST00000382841	WNK1	chr12	863490	+	IQSEC3	chr12	247432	+
intron-intron	ENST00000340908	ENST00000382841	WNK1	chr12	863490	+	IQSEC3	chr12	234799	+
intron-intron	ENST00000340908	ENST00000537151	WNK1	chr12	863490	+	IQSEC3	chr12	234799	+
intron-intron	ENST00000340908	ENST00000537151	WNK1	chr12	863490	+	IQSEC3	chr12	247433	+
intron-intron	ENST00000340908	ENST00000537151	WNK1	chr12	863490	+	IQSEC3	chr12	247432	+
intron-intron	ENST00000540360	ENST00000382841	WNK1	chr12	863490	+	IQSEC3	chr12	234799	+
intron-intron	ENST00000540360	ENST00000537151	WNK1	chr12	863490	+	IQSEC3	chr12	234799	+
intron-intron	ENST00000540360	ENST00000537151	WNK1	chr12	863490	+	IQSEC3	chr12	247433	+
intron-intron	ENST00000540360	ENST00000537151	WNK1	chr12	863490	+	IQSEC3	chr12	247432	+
intron-intron	ENST00000574564	ENST00000382841	WNK1	chr12	863490	+	IQSEC3	chr12	234799	+
intron-intron	ENST00000574564	ENST00000537151	WNK1	chr12	863490	+	IQSEC3	chr12	234799	+
intron-intron	ENST00000574564	ENST00000537151	WNK1	chr12	863490	+	IQSEC3	chr12	247433	+
intron-intron	ENST00000574564	ENST00000537151	WNK1	chr12	863490	+	IQSEC3	chr12	247432	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000535572	WNK1	chr12	863490	+	ENST00000538872	IQSEC3	chr12	247433	+	7805	1732	826	4377	1183
ENST00000535572	WNK1	chr12	863490	+	ENST00000326261	IQSEC3	chr12	247433	+	7692	1732	826	4377	1183
ENST00000537687	WNK1	chr12	863490	+	ENST00000538872	IQSEC3	chr12	247433	+	7475	1402	496	4047	1183
ENST00000537687	WNK1	chr12	863490	+	ENST00000326261	IQSEC3	chr12	247433	+	7362	1402	496	4047	1183
ENST00000315939	WNK1	chr12	863490	+	ENST00000538872	IQSEC3	chr12	247433	+	7475	1402	496	4047	1183
ENST00000315939	WNK1	chr12	863490	+	ENST00000326261	IQSEC3	chr12	247433	+	7362	1402	496	4047	1183
ENST00000447667	WNK1	chr12	863490	+	ENST00000538872	IQSEC3	chr12	247433	+	7342	1269	363	3914	1183
ENST00000447667	WNK1	chr12	863490	+	ENST00000326261	IQSEC3	chr12	247433	+	7229	1269	363	3914	1183
ENST00000530271	WNK1	chr12	863490	+	ENST00000538872	IQSEC3	chr12	247433	+	6832	759	0	3404	1134
ENST00000530271	WNK1	chr12	863490	+	ENST00000326261	IQSEC3	chr12	247433	+	6719	759	0	3404	1134
ENST00000535572	WNK1	chr12	863490	+	ENST00000538872	IQSEC3	chr12	247432	+	7805	1732	826	4377	1183
ENST00000535572	WNK1	chr12	863490	+	ENST00000326261	IQSEC3	chr12	247432	+	7692	1732	826	4377	1183
ENST00000537687	WNK1	chr12	863490	+	ENST00000538872	IQSEC3	chr12	247432	+	7475	1402	496	4047	1183
ENST00000537687	WNK1	chr12	863490	+	ENST00000326261	IQSEC3	chr12	247432	+	7362	1402	496	4047	1183
ENST00000315939	WNK1	chr12	863490	+	ENST00000538872	IQSEC3	chr12	247432	+	7475	1402	496	4047	1183
ENST00000315939	WNK1	chr12	863490	+	ENST00000326261	IQSEC3	chr12	247432	+	7362	1402	496	4047	1183
ENST00000447667	WNK1	chr12	863490	+	ENST00000538872	IQSEC3	chr12	247432	+	7342	1269	363	3914	1183
ENST00000447667	WNK1	chr12	863490	+	ENST00000326261	IQSEC3	chr12	247432	+	7229	1269	363	3914	1183
ENST00000530271	WNK1	chr12	863490	+	ENST00000538872	IQSEC3	chr12	247432	+	6832	759	0	3404	1134
ENST00000530271	WNK1	chr12	863490	+	ENST00000326261	IQSEC3	chr12	247432	+	6719	759	0	3404	1134

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000535572	ENST00000538872	WNK1	chr12	863490	+	IQSEC3	chr12	247433	+	0.010967634	0.9890324
ENST00000535572	ENST00000326261	WNK1	chr12	863490	+	IQSEC3	chr12	247433	+	0.010870335	0.98912966
ENST00000537687	ENST00000538872	WNK1	chr12	863490	+	IQSEC3	chr12	247433	+	0.008118279	0.9918818
ENST00000537687	ENST00000326261	WNK1	chr12	863490	+	IQSEC3	chr12	247433	+	0.008064725	0.99193525
ENST00000315939	ENST00000538872	WNK1	chr12	863490	+	IQSEC3	chr12	247433	+	0.008118279	0.9918818
ENST00000315939	ENST00000326261	WNK1	chr12	863490	+	IQSEC3	chr12	247433	+	0.008064725	0.99193525
ENST00000447667	ENST00000538872	WNK1	chr12	863490	+	IQSEC3	chr12	247433	+	0.007544816	0.9924551
ENST00000447667	ENST00000326261	WNK1	chr12	863490	+	IQSEC3	chr12	247433	+	0.007486088	0.99251384
ENST00000530271	ENST00000538872	WNK1	chr12	863490	+	IQSEC3	chr12	247433	+	0.003976202	0.9960238
ENST00000530271	ENST00000326261	WNK1	chr12	863490	+	IQSEC3	chr12	247433	+	0.0039593	0.9960407
ENST00000535572	ENST00000538872	WNK1	chr12	863490	+	IQSEC3	chr12	247432	+	0.010967634	0.9890324
ENST00000535572	ENST00000326261	WNK1	chr12	863490	+	IQSEC3	chr12	247432	+	0.010870335	0.98912966
ENST00000537687	ENST00000538872	WNK1	chr12	863490	+	IQSEC3	chr12	247432	+	0.008118279	0.9918818
ENST00000537687	ENST00000326261	WNK1	chr12	863490	+	IQSEC3	chr12	247432	+	0.008064725	0.99193525
ENST00000315939	ENST00000538872	WNK1	chr12	863490	+	IQSEC3	chr12	247432	+	0.008118279	0.9918818
ENST00000315939	ENST00000326261	WNK1	chr12	863490	+	IQSEC3	chr12	247432	+	0.008064725	0.99193525
ENST00000447667	ENST00000538872	WNK1	chr12	863490	+	IQSEC3	chr12	247432	+	0.007544816	0.9924551
ENST00000447667	ENST00000326261	WNK1	chr12	863490	+	IQSEC3	chr12	247432	+	0.007486088	0.99251384
ENST00000530271	ENST00000538872	WNK1	chr12	863490	+	IQSEC3	chr12	247432	+	0.003976202	0.9960238
ENST00000530271	ENST00000326261	WNK1	chr12	863490	+	IQSEC3	chr12	247432	+	0.0039593	0.9960407

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Fusion Genomic Features for WNK1-IQSEC3

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
WNK1	chr12	863490	+	IQSEC3	chr12	234798	+	0.00029335	0.99970657
WNK1	chr12	863490	+	IQSEC3	chr12	247432	+	7.15E-08	0.9999999
WNK1	chr12	863490	+	IQSEC3	chr12	247432	+	7.15E-08	0.9999999
WNK1	chr12	863490	+	IQSEC3	chr12	234798	+	0.00029335	0.99970657
WNK1	chr12	863490	+	IQSEC3	chr12	247432	+	7.15E-08	0.9999999
WNK1	chr12	863490	+	IQSEC3	chr12	247432	+	7.15E-08	0.9999999

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for WNK1-IQSEC3

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:863490/chr12:247433)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	IQSEC3 Q9UPP2
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Acts as a guanine nucleotide exchange factor (GEF) for ARF1. {ECO:0000269\|PubMed:17981261}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

IQSEC3

chr12:863490

chr12:247432

ENST00000326261

964_992

301

1372.6666666666667

Coiled coil

Ontology_term=ECO:0000255

Tgene

IQSEC3

chr12:863490

chr12:247432

ENST00000382841

20_56

760.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

IQSEC3

chr12:863490

chr12:247432

ENST00000382841

964_992

760.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

IQSEC3

chr12:863490

chr12:247432

ENST00000538872

964_992

301

1183.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

IQSEC3

chr12:863490

chr12:247433

ENST00000326261

964_992

301

1372.6666666666667

Coiled coil

Ontology_term=ECO:0000255

Tgene

IQSEC3

chr12:863490

chr12:247433

ENST00000382841

20_56

760.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

IQSEC3

chr12:863490

chr12:247433

ENST00000382841

964_992

760.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

IQSEC3

chr12:863490

chr12:247433

ENST00000538872

964_992

301

1183.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

IQSEC3

chr12:863490

chr12:247432

ENST00000326261

1061_1165

301

1372.6666666666667

Compositional bias

Note=Pro-rich

Tgene

IQSEC3

chr12:863490

chr12:247432

ENST00000326261

572_579

301

1372.6666666666667

Compositional bias

Note=Poly-Glu

Tgene

IQSEC3

chr12:863490

chr12:247432

ENST00000326261

598_603

301

1372.6666666666667

Compositional bias

Note=Poly-Ser

Tgene

IQSEC3

chr12:863490

chr12:247432

ENST00000382841

1061_1165

760.0

Compositional bias

Note=Pro-rich

Tgene

IQSEC3

chr12:863490

chr12:247432

ENST00000382841

225_231

760.0

Compositional bias

Note=Poly-Ala

Tgene

IQSEC3

chr12:863490

chr12:247432

ENST00000382841

248_251

760.0

Compositional bias

Note=Poly-Glu

Tgene

IQSEC3

chr12:863490

chr12:247432

ENST00000382841

572_579

760.0

Compositional bias

Note=Poly-Glu

Tgene

IQSEC3

chr12:863490

chr12:247432

ENST00000382841

598_603

760.0

Compositional bias

Note=Poly-Ser

Tgene

IQSEC3

chr12:863490

chr12:247432

ENST00000382841

78_90

760.0

Compositional bias

Note=Poly-Ala

Tgene

IQSEC3

chr12:863490

chr12:247432

ENST00000538872

1061_1165

301

1183.0

Compositional bias

Note=Pro-rich

Tgene

IQSEC3

chr12:863490

chr12:247432

ENST00000538872

572_579

301

1183.0

Compositional bias

Note=Poly-Glu

Tgene

IQSEC3

chr12:863490

chr12:247432

ENST00000538872

598_603

301

1183.0

Compositional bias

Note=Poly-Ser

Tgene

IQSEC3

chr12:863490

chr12:247433

ENST00000326261

1061_1165

301

1372.6666666666667

Compositional bias

Note=Pro-rich

Tgene

IQSEC3

chr12:863490

chr12:247433

ENST00000326261

572_579

301

1372.6666666666667

Compositional bias

Note=Poly-Glu

Tgene

IQSEC3

chr12:863490

chr12:247433

ENST00000326261

598_603

301

1372.6666666666667

Compositional bias

Note=Poly-Ser

Tgene

IQSEC3

chr12:863490

chr12:247433

ENST00000382841

1061_1165

760.0

Compositional bias

Note=Pro-rich

Tgene

IQSEC3

chr12:863490

chr12:247433

ENST00000382841

225_231

760.0

Compositional bias

Note=Poly-Ala

Tgene

IQSEC3

chr12:863490

chr12:247433

ENST00000382841

248_251

760.0

Compositional bias

Note=Poly-Glu

Tgene

IQSEC3

chr12:863490

chr12:247433

ENST00000382841

572_579

760.0

Compositional bias

Note=Poly-Glu

Tgene

IQSEC3

chr12:863490

chr12:247433

ENST00000382841

598_603

760.0

Compositional bias

Note=Poly-Ser

Tgene

IQSEC3

chr12:863490

chr12:247433

ENST00000382841

78_90

760.0

Compositional bias

Note=Poly-Ala

Tgene

IQSEC3

chr12:863490

chr12:247433

ENST00000538872

1061_1165

301

1183.0

Compositional bias

Note=Pro-rich

Tgene

IQSEC3

chr12:863490

chr12:247433

ENST00000538872

572_579

301

1183.0

Compositional bias

Note=Poly-Glu

Tgene

IQSEC3

chr12:863490

chr12:247433

ENST00000538872

598_603

301

1183.0

Compositional bias

Note=Poly-Ser

Tgene

IQSEC3

chr12:863490

chr12:247432

ENST00000326261

315_344

301

1372.6666666666667

Domain

Tgene

IQSEC3

chr12:863490

chr12:247432

ENST00000326261

644_837

301

1372.6666666666667

Domain

SEC7

Tgene

IQSEC3

chr12:863490

chr12:247432

ENST00000326261

850_983

301

1372.6666666666667

Domain

Note=PH

Tgene

IQSEC3

chr12:863490

chr12:247432

ENST00000382841

315_344

760.0

Domain

Tgene

IQSEC3

chr12:863490

chr12:247432

ENST00000382841

644_837

760.0

Domain

SEC7

Tgene

IQSEC3

chr12:863490

chr12:247432

ENST00000382841

850_983

760.0

Domain

Note=PH

Tgene

IQSEC3

chr12:863490

chr12:247432

ENST00000538872

315_344

301

1183.0

Domain

Tgene

IQSEC3

chr12:863490

chr12:247432

ENST00000538872

644_837

301

1183.0

Domain

SEC7

Tgene

IQSEC3

chr12:863490

chr12:247432

ENST00000538872

850_983

301

1183.0

Domain

Note=PH

Tgene

IQSEC3

chr12:863490

chr12:247433

ENST00000326261

315_344

301

1372.6666666666667

Domain

Tgene

IQSEC3

chr12:863490

chr12:247433

ENST00000326261

644_837

301

1372.6666666666667

Domain

SEC7

Tgene

IQSEC3

chr12:863490

chr12:247433

ENST00000326261

850_983

301

1372.6666666666667

Domain

Note=PH

Tgene

IQSEC3

chr12:863490

chr12:247433

ENST00000382841

315_344

760.0

Domain

Tgene

IQSEC3

chr12:863490

chr12:247433

ENST00000382841

644_837

760.0

Domain

SEC7

Tgene

IQSEC3

chr12:863490

chr12:247433

ENST00000382841

850_983

760.0

Domain

Note=PH

Tgene

IQSEC3

chr12:863490

chr12:247433

ENST00000538872

315_344

301

1183.0

Domain

Tgene

IQSEC3

chr12:863490

chr12:247433

ENST00000538872

644_837

301

1183.0

Domain

SEC7

Tgene

IQSEC3

chr12:863490

chr12:247433

ENST00000538872

850_983

301

1183.0

Domain

Note=PH

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

WNK1

chr12:863490

chr12:247432

ENST00000315939

221_479

253

2383.0

Domain

Protein kinase

Hgene

WNK1

chr12:863490

chr12:247432

ENST00000340908

221_479

1976.0

Domain

Protein kinase

Hgene

WNK1

chr12:863490

chr12:247432

ENST00000537687

221_479

253

2643.0

Domain

Protein kinase

Hgene

WNK1

chr12:863490

chr12:247432

ENST00000574564

221_479

435.0

Domain

Protein kinase

Hgene

WNK1

chr12:863490

chr12:247433

ENST00000315939

221_479

253

2383.0

Domain

Protein kinase

Hgene

WNK1

chr12:863490

chr12:247433

ENST00000340908

221_479

1976.0

Domain

Protein kinase

Hgene

WNK1

chr12:863490

chr12:247433

ENST00000537687

221_479

253

2643.0

Domain

Protein kinase

Hgene

WNK1

chr12:863490

chr12:247433

ENST00000574564

221_479

435.0

Domain

Protein kinase

Hgene

WNK1

chr12:863490

chr12:247432

ENST00000315939

301_304

253

2383.0

Nucleotide binding

ATP

Hgene

WNK1

chr12:863490

chr12:247432

ENST00000340908

301_304

1976.0

Nucleotide binding

ATP

Hgene

WNK1

chr12:863490

chr12:247432

ENST00000537687

301_304

253

2643.0

Nucleotide binding

ATP

Hgene

WNK1

chr12:863490

chr12:247432

ENST00000574564

301_304

435.0

Nucleotide binding

ATP

Hgene

WNK1

chr12:863490

chr12:247433

ENST00000315939

301_304

253

2383.0

Nucleotide binding

ATP

Hgene

WNK1

chr12:863490

chr12:247433

ENST00000340908

301_304

1976.0

Nucleotide binding

ATP

Hgene

WNK1

chr12:863490

chr12:247433

ENST00000537687

301_304

253

2643.0

Nucleotide binding

ATP

Hgene

WNK1

chr12:863490

chr12:247433

ENST00000574564

301_304

435.0

Nucleotide binding

ATP

Hgene

WNK1

chr12:863490

chr12:247432

ENST00000315939

488_555

253

2383.0

Region

Autoinhibitory domain

Hgene

WNK1

chr12:863490

chr12:247432

ENST00000340908

488_555

1976.0

Region

Autoinhibitory domain

Hgene

WNK1

chr12:863490

chr12:247432

ENST00000537687

488_555

253

2643.0

Region

Autoinhibitory domain

Hgene

WNK1

chr12:863490

chr12:247432

ENST00000574564

488_555

435.0

Region

Autoinhibitory domain

Hgene

WNK1

chr12:863490

chr12:247433

ENST00000315939

488_555

253

2383.0

Region

Autoinhibitory domain

Hgene

WNK1

chr12:863490

chr12:247433

ENST00000340908

488_555

1976.0

Region

Autoinhibitory domain

Hgene

WNK1

chr12:863490

chr12:247433

ENST00000537687

488_555

253

2643.0

Region

Autoinhibitory domain

Hgene

WNK1

chr12:863490

chr12:247433

ENST00000574564

488_555

435.0

Region

Autoinhibitory domain

Tgene

IQSEC3

chr12:863490

chr12:247432

ENST00000326261

20_56

301

1372.6666666666667

Coiled coil

Ontology_term=ECO:0000255

Tgene

IQSEC3

chr12:863490

chr12:247432

ENST00000538872

20_56

301

1183.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

IQSEC3

chr12:863490

chr12:247433

ENST00000326261

20_56

301

1372.6666666666667

Coiled coil

Ontology_term=ECO:0000255

Tgene

IQSEC3

chr12:863490

chr12:247433

ENST00000538872

20_56

301

1183.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

IQSEC3

chr12:863490

chr12:247432

ENST00000326261

225_231

301

1372.6666666666667

Compositional bias

Note=Poly-Ala

Tgene

IQSEC3

chr12:863490

chr12:247432

ENST00000326261

248_251

301

1372.6666666666667

Compositional bias

Note=Poly-Glu

Tgene

IQSEC3

chr12:863490

chr12:247432

ENST00000326261

78_90

301

1372.6666666666667

Compositional bias

Note=Poly-Ala

Tgene

IQSEC3

chr12:863490

chr12:247432

ENST00000538872

225_231

301

1183.0

Compositional bias

Note=Poly-Ala

Tgene

IQSEC3

chr12:863490

chr12:247432

ENST00000538872

248_251

301

1183.0

Compositional bias

Note=Poly-Glu

Tgene

IQSEC3

chr12:863490

chr12:247432

ENST00000538872

78_90

301

1183.0

Compositional bias

Note=Poly-Ala

Tgene

IQSEC3

chr12:863490

chr12:247433

ENST00000326261

225_231

301

1372.6666666666667

Compositional bias

Note=Poly-Ala

Tgene

IQSEC3

chr12:863490

chr12:247433

ENST00000326261

248_251

301

1372.6666666666667

Compositional bias

Note=Poly-Glu

Tgene

IQSEC3

chr12:863490

chr12:247433

ENST00000326261

78_90

301

1372.6666666666667

Compositional bias

Note=Poly-Ala

Tgene

IQSEC3

chr12:863490

chr12:247433

ENST00000538872

225_231

301

1183.0

Compositional bias

Note=Poly-Ala

Tgene

IQSEC3

chr12:863490

chr12:247433

ENST00000538872

248_251

301

1183.0

Compositional bias

Note=Poly-Glu

Tgene

IQSEC3

chr12:863490

chr12:247433

ENST00000538872

78_90

301

1183.0

Compositional bias

Note=Poly-Ala

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Fusion Gene Sequence for WNK1-IQSEC3

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>99331_99331_1_WNK1-IQSEC3_WNK1_chr12_863490_ENST00000315939_IQSEC3_chr12_247432_ENST00000326261_length(transcript)=7362nt_BP=1402nt
CCGGCCCTTCGCCTCTGGGCGATGGGCGACCTGTGAGGCCGGTCCCCATCGCTGGGGGCGCGTGTGGGAGGAGGCGGCCGCCCGAGTGAC
CGGGAGCCGGGCCGCGGCCTTCCCTCGCCCGCCTCGGCCCCTCCCACTCCTCTGCCCCGGGGCCGCCACCGCCCGGGCGTCGGACCTGGT
CCCGTGCTCGCGGTGCCGCCGCCCTCTGGGCCTAGCCCGCCCAGCTCGGCGAGCGGCGGCAGTGGGAGCCGCGTCCGCCGCATCCGCCTC
GACTCGGTGCCGGCCCCTGGCCCTCCCCTCATGACTGCGGCGCCTCTGCTGCCACCGCCCGCCCGGCCGCCGCTCGCCGCAGGATGGATG
CGGACCGTGCGGCGCTAACCCCCGTGGCTCAGCTCCCGAATCGCCCGCCTTCGAGCCCTCCTCGTGAGCCGCAGCAGCCTCGGTGCCAGC
CCCCGCCGCAGCTGGGCCCAGCGGTCCGCCTGTCCCTCGTTGCGGCTTGTCGGTGCTGAGTGAGGCGTCGTCCGGGTCGGCGCGAACCCG
CCCGGCCGCGGTTCCCTGCAGACCTCTGCGCGGGCGGCTCGGCCCTTCACGCCCTTTTCGTTCACGAATCCGAGCCCGCTCGCCTCTCTC
CAGCGAACCGACCATGTCTGGCGGCGCCGCAGAGAAGCAGAGCAGCACTCCCGGTTCCCTGTTCCTCTCGCCGCCGGCTCCTGCCCCCAA
GAATGGCTCCAGCTCCGATTCCTCCGTGGGGGAGAAACTGGGAGCCGCGGCCGCCGACGCTGTGACCGGCAGGACCGAGGAGTACAGGCG
CCGCCGCCACACTATGGACAAGGACAGCCGTGGGGCGGCCGCGACCACTACCACCACTGAGCACCGCTTCTTCCGCCGGAGCGTCATCTG
TGACTCCAATGCCACTGCACTGGAGCTTCCCGGCCTTCCTCTTTCCCTGCCCCAGCCCAGCATCCCCGCGGCTGTCCCGCAGAGTGCTCC
ACCGGAGCCCCACCGGGAAGAGACCGTGACCGCCACCGCCACTTCCCAGGTAGCCCAGCAGCCTCCAGCCGCTGCCGCCCCTGGGGAACA
GGCCGTCGCGGGCCCTGCCCCCTCGACTGTCCCCAGCAGTACCAGCAAAGACCGCCCAGTGTCCCAGCCTAGCCTTGTGGGGAGCAAAGA
GGAGCCGCCGCCGGCGAGAAGTGGCAGCGGCGGCGGCAGCGCCAAGGAGCCACAGGAGGAACGGAGCCAGCAGCAGGATGATATCGAAGA
GCTGGAGACCAAGGCCGTGGGAATGTCTAACGATGGCCGCTTTCTCAAGTTTGACATCGAAATCGGCAGAGGCTCCTTTAAGACGGTCTA
CAAAGGTCTGGACACTGAAACCACCGTGGAAGTCGCCTGGTGTGAACTGCAGATTGAAATGCTAGAACATAAGTACGGCGGTCACCTGGT
GTCCCGGCGCGCCGCTTGCACCATCCAAACCGCCTTCCGCCAATACCAGCTCAGCAAGAACTTCGAGAAAATCCGCAACTCGCTTCTGGA
GAGCCGCCTGCCACGGCGGATCTCCCTGCGCAAGGTGCGGTCACCCACGGCCGAGAGCCTGGCGGCCGAGAAAGCGCTCATGGAGGGCTA
CGGCCTCGTGGGGCTGCCGCTGGTGCGCTCGCCCTCCCTGCCGCCCACCTTCGCAGGCACCCTCACCGAGCTGGAGGACTCCTTCACCGA
GCAGGTGCAATCCCTGGCCAAGTCCATCGACGACGCGCTCAGCACGTGGAGCCTCAAGACCATGTGCTCCCTGCGGGAGAGTGGCGCTTA
CCAGCTCCACCAGGCCCTGCAGGCGGCCGCGGGGCCCCCAGGCCTGGAGGCCGAGGGGCGGGCGCCGGAGAGCGCGGGCCCCGGGCCCGG
GGATGACGCCGCGGAGACCCCCGGCCTGCCCCCGGCCCACAGCGGGACCCTCATGATGGCTTTCCGGGACGTCACGGTGCAGATCGCCAA
CCAGAACATATCCGTCTCCTCCTCCACGGCTCTGTCGGTGGCCAACTGCCTGGGCGCTCAGACGGTCCAGGCCCCCGCAGAGCCCGCGGC
GGGCAAGGCCGAGCAGGGCGAGACCTCTGGGCGGGAGGCCCCGGAAGCCCCCGCCGTGGGCCGGGAGGACGCGTCAGCCGAGGACTCATG
CGCAGAGGCTGCGGCTAGTGGGGCGGCGGATGGGGCCACAGCCCCCAAAACAGAGGAGGAAGAGGAGGAGGAGGAGACGGCGGAGGTGGG
GAGAGGGGCCGAGGCCGAGGCAGGCGACTTGGAGCAGCTGAGCAGCAGCAGCACGTCCACCAAGTCCGCCAAGTCAGGCTCGGAGGCGTC
GGCCTCCGCCTCCAAGGACGCCCTGCAGGCCATGATCCTGAGCCTGCCGCGCTACCACTGCGAGAACCCAGCCAGCTGCAAGTCGCCCAC
GCTCTCCACCGACACCCTGCGCAAGCGGCTCTACCGCATCGGCCTCAACCTCTTCAACATAAACCCCGACAAGGGCATCCAGTTCCTGAT
CTCACGCGGCTTCATCCCGGACACCCCCATCGGTGTGGCCCATTTCCTCCTCCAGCGAAAGGGCCTCAGCCGCCAGATGATTGGAGAGTT
CCTGGGCAACAGCAAGAAGCAGTTCAACCGCGACGTGCTGGACTGCGTGGTGGACGAGATGGACTTCTCCAGCATGGAGCTGGACGAGGC
CCTGCGCAAGTTCCAGGCACACATCCGTGTGCAGGGGGAGGCTCAGAAGGTGGAGCGGCTCATTGAGGCCTTCAGCCAGCGCTACTGCAT
GTGCAACCCCGAAGTGGTTCAGCAGTTCCACAACCCCGACACCATCTTCATCCTCGCCTTCGCCATCATCCTCCTCAACACCGACATGTA
CAGCCCCAACATCAAGCCTGACCGGAAGATGATGCTGGAGGACTTCATCCGAAACCTTCGAGGTGTGGACGATGGCGCTGACATCCCCAG
GGAGCTGGTGGTAGGCATCTATGAGAGGATACAGCAGAAGGAGCTCAAGTCCAATGAGGACCACGTCACGTACGTCACCAAGGTGGAGAA
GTCCATTGTGGGCATGAAGACAGTGCTGTCCGTGCCCCACCGCCGCCTGGTGTGCTGCAGCCGGCTCTTCGAGGTGACGGATGTGAACAA
GCTGCAGAAGCAGGCAGCGCATCAGAGGGAGGTGTTCCTCTTCAATGACCTGCTGGTGATTCTCAAACTTTGCCCGAAGAAGAAGAGCTC
CTCCACGTACACCTTTTGCAAGTCAGTTGGCCTGCTGGGCATGCAGTTCCAGCTCTTTGAGAACGAGTATTACTCTCATGGCATCACACT
GGTGACCCCGCTCTCGGGCTCCGAGAAGAAGCAGGTGCTGCATTTCTGTGCCCTGGGCTCGGACGAGATGCAGAAGTTCGTGGAGGACCT
GAAGGAGTCCATTGCTGAGGTGACGGAGCTGGAGCAGATCCGAATAGAGTGGGAGCTGGAGAAGCAGCAGGGAACAAAGACACTCTCCTT
CAAGCCCTGCGGAGCCCAGGGGGACCCACAGTCAAAGCAAGGATCGCCGACAGCCAAAAGGGAAGCCGCGCTCAGGGAGAGGCCGGCGGA
GAGCACGGTGGAGGTGTCAATTCACAACAGGCTTCAAACGTCCCAGCACAACTCCGGGCTGGGGGCCGAGAGGGGAGCGCCGGTGCCGCC
GCCAGACCTGCAGCCTAGCCCCCCGAGACAGCAGACCCCACCACTGCCGCCGCCGCCACCCACGCCCCCGGGCACCCTGGTGCAGTGCCA
GCAAATTGTCAAGGTCATTGTCCTGGACAAGCCCTGCCTGGCCCGCATGGAGCCCCTGCTGAGCCAGGCTCTCTCCTGCTACACCTCGTC
GTCCTCTGACTCCTGCGGCTCCACACCCCTGGGCGGTCCCGGCTCTCCGGTCAAGGTCACCCACCAGCCTCCGCTGCCCCCGCCCCCACC
CCCCTACAACCACCCTCACCAGTTCTGTCCCCCAGGCTCCCTGCTGCACGGGCACCGCTACTCCAGTGGCTCAAGGAGCCTGGTGTAGAC
TCTGCCCCACCACCCTGCTGTCCTGGGAGGGCTGGCCACTGGGGGGCCTGGGCTGCCCCTCCACTGCTCCCCATACCCTGGCACGATGCG
TTCCTGGTCACTGATCACCATCATTTTGGGAAGAGAATCCCAATCCCTGGCACCTGGGTTTGCCTCATCCAACCATCCTTCCCTTTCTCA
GCTGCACCCCCTCTGCAGATCTGAAGACACACCTCACTCTCCCAGGGCCCTACACAGCCAGACCCGGCGAGGCCTCCTCTTCCCCTGGCC
ACCACTTTCCCCCATTGGACCATGGACTGAAGAAAACGAGCTGAGGGTCTAACGAGCTTGCAGGCTTTGAGTCTGTTAGTGCCCGGGGCC
TCGGGCCTTGGGCAGCAGCATGAGGCTGGGCCGGCCGGCAGTGGAGCACTAGACAGAGTGGCTGGCTCGCAGCCCAGAACTAGTGCCTCT
GTAGCTGCACTGAGGGGAGGAGGGTTGGTCCCACCCCTGGAGGGACAGGTGGGAGGAGTGAGGAGGGGGCTTTTTCTGCCACCCCCGCCC
CCAAGCCTGAAACTCTCAGGAGTCTACTTCTTGGTCCCCAGGGACATTGGCTGTCCTGACCATGTCCTTCCCCCTCCTCCCAGGGCCTCT
GCTTCCTCAGGAGCTGCCCAGACTCCAGAAAAGCCTGGAAAAAGGGAGGCGGGAAGGGGAGCACTTTCGGCTTTCTATAGGTCAGTCCAG
CAGGGCCACGGGATCGCGAGGTCATGTATCTGCAAAATGCACCTTTTTAAAGAGTGTCTTAGTTCCCCAGCCCCAGCTAATACCCGGCCA
ATGCCGTGTACGCACCGGCATGTGCACGCAAACACGCATGAGAACCAGGCCATTCCTTCCGCTGTGGAAGCAGAACTGGAGACGGGGCAG
GAATGTGCCCAGCAGAGATGGGGCTCAGCCCGAGGCAGGGCTCCCTCCTGCATGAGGCTCGGCCCGAGGCAGGGCTCCCTCCTGCATGAG
TCTGTGGCCTCCAGGAGGGACTTGGGTGCAGATGTAAGCAAGAAAAACCGGGGCTCCAGAGGCATGTGCATTTCCCCTGCGCCCCTCAGC
CTTTAAATATTCCCTCCTCCTAGAAGGTTCTAGACCCCCCCCTTCCAGCAGGGGTGCCCAAGAGTCCCTGGACCCTCAAAATTGCAAAGG
AGACCCAAGCGGGGCTCGCTGACCTCCCAGGGCCCAGCAAGATGGGATAGCCAGCCTTAGGTGGCCCCACGAGCCCAAGCCTGGGGAAGG
GCCCCTCCCCAGCCAGACGAGAGGCAGCCACCCCAGAGACCACAGGAGCCGTACCATGGCCTGCGCAGTCAGGCCCTATCAGGATGTGTC
TGTCCCAAGCCTGGCCAGGCTCCAGTCCTGTGCCAGTAGCTCACTGCTGTCCTATGTGCAGGTCCCCCAACACTTGGAGCCTGTGGTTAA
GGCCTCCTGGGAGAGGCAGTGAGCATGAGTCAAAGGTGACATGGACTTGAATCTCCCCACCCCGCCCCGCCTGCAGTAGCCGGGCCAGGT
AGGAGGCAAGGATCATTCCCTGCTCCCAGAGGTTCCAGATGACCTAGTTTCGTTTTGTGTGTGTGTGTGTGTGGTCACCCAGACGTCACT
GTGATATCACCTAGTGAATCTATTTCTGGCCCTGTCTTCGTCGGCCCAGTTTCTGTAACTTGCAGCCAATTTGCCCTCTCCCCTGTGGCT
GCCAGCCCATCTGCCCCTCTGTGTCCTTGCTGCCCTGGCCCTCCTCTGTTTTCTGTAACAGATGCTCCAGTCATTGCCTTTCAGAGTGGA
GCAGATGACAGATGGGGTGCACGCATTCAGACACCTCTGATGCCCTTAGCCAGGGCAGGGATCGTCCTTAAAGTGAAGGCCTGGACAGGA
GGAGTCAGGGACTTGGGAGGAGGTGGAGCTGTGGGGATGGGAGTGGAGGAATCAAAATGAGGGAAGCTGAAAATAGAATGAAAACGATGA
CTAAGAGGCAGGGAGTGCGAGGTATGGGGGAATAGGAACTATGAGCTAAATATACTTATGGGGTGGGGGCCGTGGGGGCCAGGGACACTC
TCCCAGACAGCCCTGACCCGCCAGGCAGGACCCCGTCCCCTGCTCACACAGCTCTTCAAACTTACCAAGGACAGGCAGGACCCCGTCCCC
TGCTCACACAGCTCTTCAAGCTTACCAAGTCCCCTGTTGAGGGCACAGCAACCCCAGGCCCTCCCTCCCACCTCAGCTGAAGCCCCAATC
TTCCAAATCGGAACCAGCAAGTCTTAGGGCTGGCACGCATCTGGGCCTCTAGCTGAGAACCCGGACTCTCAGGCACCTCAGTGCCCCTGC
CCCAGGGCAGAGGCCCACCCCGTGGGTTGGTGCAGTGGCTGCCCTGGGCTCCACGGGCAGCACAGGGAGTCTGTCCAGGAAGCAGCCCAG
CCGGGGTCAGTATTCCGTGGAGCCAGTCCTGAGCTGGGAGGGGCATTTAACACCCCTGAGGGCCTGGGGCAGGACACAGCTGGCCCTCCT
CATTGTCAGGGGAAGCAAGTGCCCAACATCTGTAACCTCCCTTCCCTGCTCAGTCCCCAGGCCAAGGTTGGGACCCCTCTCCATCCCTGT
CCCCAGAGCCTAGACCTCAGGGACCTAGGAAAAGCCTCCTGCTCCCTCCCCACGGCAGCAGACAGGGCAGGGCCTCCAGCCCCCAGAGGG
CCGGTGGGGGGTGCTCTCGGGCCTTCCTGCTCTCCTAAGGTTGCGGGGACAGTAGAGTGCTGAGCCCCAGACCCAGTCACCCCAAGATGG
CCCCACTCTATCCACTCTCTAGACCTTTGGGAAATCTGGGTCCCTCTCCTGATTTGATCCATTCGGCCCCAACTCCAGAGTCGGGAATGG
GAGATGAAACTAGTTTTCCACCCACTTTTGGACAAGTCCCACCCCTAGATCTGAAGCAAGCTCTACCAGCAGCGTGTCCTGGAAGCCTGC
CTGCCTGCCTGCCCGTCTGCACAGGTGTCTTGATCCAGCCCTGCGTCTTCGAGCCCCTGTGCCACCGGTCCCCACGGCCCGCCAGGAGTC
TCTTTGTACCCACTAGGCTTCCCTGATGACCATCTGTCTGTCCGTCCCTGTTTTTGCTGTACATAACTCCTGCTGCACCCTCTCCCCGCA
CACCCGTCACCCATGAGAGAGAGAAACCTCTCTAGGGAAAGGCAGGGTGGCTGCACCCAGCAACTAATCCAAATGGCAAATATTTTGTAA

>99331_99331_1_WNK1-IQSEC3_WNK1_chr12_863490_ENST00000315939_IQSEC3_chr12_247432_ENST00000326261_length(amino acids)=1183AA_BP=300
MSVLSEASSGSARTRPAAVPCRPLRGRLGPSRPFRSRIRARSPLSSEPTMSGGAAEKQSSTPGSLFLSPPAPAPKNGSSSDSSVGEKLGA
AAADAVTGRTEEYRRRRHTMDKDSRGAAATTTTTEHRFFRRSVICDSNATALELPGLPLSLPQPSIPAAVPQSAPPEPHREETVTATATS
QVAQQPPAAAAPGEQAVAGPAPSTVPSSTSKDRPVSQPSLVGSKEEPPPARSGSGGGSAKEPQEERSQQQDDIEELETKAVGMSNDGRFL
KFDIEIGRGSFKTVYKGLDTETTVEVAWCELQIEMLEHKYGGHLVSRRAACTIQTAFRQYQLSKNFEKIRNSLLESRLPRRISLRKVRSP
TAESLAAEKALMEGYGLVGLPLVRSPSLPPTFAGTLTELEDSFTEQVQSLAKSIDDALSTWSLKTMCSLRESGAYQLHQALQAAAGPPGL
EAEGRAPESAGPGPGDDAAETPGLPPAHSGTLMMAFRDVTVQIANQNISVSSSTALSVANCLGAQTVQAPAEPAAGKAEQGETSGREAPE
APAVGREDASAEDSCAEAAASGAADGATAPKTEEEEEEEETAEVGRGAEAEAGDLEQLSSSSTSTKSAKSGSEASASASKDALQAMILSL
PRYHCENPASCKSPTLSTDTLRKRLYRIGLNLFNINPDKGIQFLISRGFIPDTPIGVAHFLLQRKGLSRQMIGEFLGNSKKQFNRDVLDC
VVDEMDFSSMELDEALRKFQAHIRVQGEAQKVERLIEAFSQRYCMCNPEVVQQFHNPDTIFILAFAIILLNTDMYSPNIKPDRKMMLEDF
IRNLRGVDDGADIPRELVVGIYERIQQKELKSNEDHVTYVTKVEKSIVGMKTVLSVPHRRLVCCSRLFEVTDVNKLQKQAAHQREVFLFN
DLLVILKLCPKKKSSSTYTFCKSVGLLGMQFQLFENEYYSHGITLVTPLSGSEKKQVLHFCALGSDEMQKFVEDLKESIAEVTELEQIRI
EWELEKQQGTKTLSFKPCGAQGDPQSKQGSPTAKREAALRERPAESTVEVSIHNRLQTSQHNSGLGAERGAPVPPPDLQPSPPRQQTPPL
PPPPPTPPGTLVQCQQIVKVIVLDKPCLARMEPLLSQALSCYTSSSSDSCGSTPLGGPGSPVKVTHQPPLPPPPPPYNHPHQFCPPGSLL

--------------------------------------------------------------
>99331_99331_2_WNK1-IQSEC3_WNK1_chr12_863490_ENST00000315939_IQSEC3_chr12_247432_ENST00000538872_length(transcript)=7475nt_BP=1402nt
CCGGCCCTTCGCCTCTGGGCGATGGGCGACCTGTGAGGCCGGTCCCCATCGCTGGGGGCGCGTGTGGGAGGAGGCGGCCGCCCGAGTGAC
CGGGAGCCGGGCCGCGGCCTTCCCTCGCCCGCCTCGGCCCCTCCCACTCCTCTGCCCCGGGGCCGCCACCGCCCGGGCGTCGGACCTGGT
CCCGTGCTCGCGGTGCCGCCGCCCTCTGGGCCTAGCCCGCCCAGCTCGGCGAGCGGCGGCAGTGGGAGCCGCGTCCGCCGCATCCGCCTC
GACTCGGTGCCGGCCCCTGGCCCTCCCCTCATGACTGCGGCGCCTCTGCTGCCACCGCCCGCCCGGCCGCCGCTCGCCGCAGGATGGATG
CGGACCGTGCGGCGCTAACCCCCGTGGCTCAGCTCCCGAATCGCCCGCCTTCGAGCCCTCCTCGTGAGCCGCAGCAGCCTCGGTGCCAGC
CCCCGCCGCAGCTGGGCCCAGCGGTCCGCCTGTCCCTCGTTGCGGCTTGTCGGTGCTGAGTGAGGCGTCGTCCGGGTCGGCGCGAACCCG
CCCGGCCGCGGTTCCCTGCAGACCTCTGCGCGGGCGGCTCGGCCCTTCACGCCCTTTTCGTTCACGAATCCGAGCCCGCTCGCCTCTCTC
CAGCGAACCGACCATGTCTGGCGGCGCCGCAGAGAAGCAGAGCAGCACTCCCGGTTCCCTGTTCCTCTCGCCGCCGGCTCCTGCCCCCAA
GAATGGCTCCAGCTCCGATTCCTCCGTGGGGGAGAAACTGGGAGCCGCGGCCGCCGACGCTGTGACCGGCAGGACCGAGGAGTACAGGCG
CCGCCGCCACACTATGGACAAGGACAGCCGTGGGGCGGCCGCGACCACTACCACCACTGAGCACCGCTTCTTCCGCCGGAGCGTCATCTG
TGACTCCAATGCCACTGCACTGGAGCTTCCCGGCCTTCCTCTTTCCCTGCCCCAGCCCAGCATCCCCGCGGCTGTCCCGCAGAGTGCTCC
ACCGGAGCCCCACCGGGAAGAGACCGTGACCGCCACCGCCACTTCCCAGGTAGCCCAGCAGCCTCCAGCCGCTGCCGCCCCTGGGGAACA
GGCCGTCGCGGGCCCTGCCCCCTCGACTGTCCCCAGCAGTACCAGCAAAGACCGCCCAGTGTCCCAGCCTAGCCTTGTGGGGAGCAAAGA
GGAGCCGCCGCCGGCGAGAAGTGGCAGCGGCGGCGGCAGCGCCAAGGAGCCACAGGAGGAACGGAGCCAGCAGCAGGATGATATCGAAGA
GCTGGAGACCAAGGCCGTGGGAATGTCTAACGATGGCCGCTTTCTCAAGTTTGACATCGAAATCGGCAGAGGCTCCTTTAAGACGGTCTA
CAAAGGTCTGGACACTGAAACCACCGTGGAAGTCGCCTGGTGTGAACTGCAGATTGAAATGCTAGAACATAAGTACGGCGGTCACCTGGT
GTCCCGGCGCGCCGCTTGCACCATCCAAACCGCCTTCCGCCAATACCAGCTCAGCAAGAACTTCGAGAAAATCCGCAACTCGCTTCTGGA
GAGCCGCCTGCCACGGCGGATCTCCCTGCGCAAGGTGCGGTCACCCACGGCCGAGAGCCTGGCGGCCGAGAAAGCGCTCATGGAGGGCTA
CGGCCTCGTGGGGCTGCCGCTGGTGCGCTCGCCCTCCCTGCCGCCCACCTTCGCAGGCACCCTCACCGAGCTGGAGGACTCCTTCACCGA
GCAGGTGCAATCCCTGGCCAAGTCCATCGACGACGCGCTCAGCACGTGGAGCCTCAAGACCATGTGCTCCCTGCGGGAGAGTGGCGCTTA
CCAGCTCCACCAGGCCCTGCAGGCGGCCGCGGGGCCCCCAGGCCTGGAGGCCGAGGGGCGGGCGCCGGAGAGCGCGGGCCCCGGGCCCGG
GGATGACGCCGCGGAGACCCCCGGCCTGCCCCCGGCCCACAGCGGGACCCTCATGATGGCTTTCCGGGACGTCACGGTGCAGATCGCCAA
CCAGAACATATCCGTCTCCTCCTCCACGGCTCTGTCGGTGGCCAACTGCCTGGGCGCTCAGACGGTCCAGGCCCCCGCAGAGCCCGCGGC
GGGCAAGGCCGAGCAGGGCGAGACCTCTGGGCGGGAGGCCCCGGAAGCCCCCGCCGTGGGCCGGGAGGACGCGTCAGCCGAGGACTCATG
CGCAGAGGCTGCGGCTAGTGGGGCGGCGGATGGGGCCACAGCCCCCAAAACAGAGGAGGAAGAGGAGGAGGAGGAGACGGCGGAGGTGGG
GAGAGGGGCCGAGGCCGAGGCAGGCGACTTGGAGCAGCTGAGCAGCAGCAGCACGTCCACCAAGTCCGCCAAGTCAGGCTCGGAGGCGTC
GGCCTCCGCCTCCAAGGACGCCCTGCAGGCCATGATCCTGAGCCTGCCGCGCTACCACTGCGAGAACCCAGCCAGCTGCAAGTCGCCCAC
GCTCTCCACCGACACCCTGCGCAAGCGGCTCTACCGCATCGGCCTCAACCTCTTCAACATAAACCCCGACAAGGGCATCCAGTTCCTGAT
CTCACGCGGCTTCATCCCGGACACCCCCATCGGTGTGGCCCATTTCCTCCTCCAGCGAAAGGGCCTCAGCCGCCAGATGATTGGAGAGTT
CCTGGGCAACAGCAAGAAGCAGTTCAACCGCGACGTGCTGGACTGCGTGGTGGACGAGATGGACTTCTCCAGCATGGAGCTGGACGAGGC
CCTGCGCAAGTTCCAGGCACACATCCGTGTGCAGGGGGAGGCTCAGAAGGTGGAGCGGCTCATTGAGGCCTTCAGCCAGCGCTACTGCAT
GTGCAACCCCGAAGTGGTTCAGCAGTTCCACAACCCCGACACCATCTTCATCCTCGCCTTCGCCATCATCCTCCTCAACACCGACATGTA
CAGCCCCAACATCAAGCCTGACCGGAAGATGATGCTGGAGGACTTCATCCGAAACCTTCGAGGTGTGGACGATGGCGCTGACATCCCCAG
GGAGCTGGTGGTAGGCATCTATGAGAGGATACAGCAGAAGGAGCTCAAGTCCAATGAGGACCACGTCACGTACGTCACCAAGGTGGAGAA
GTCCATTGTGGGCATGAAGACAGTGCTGTCCGTGCCCCACCGCCGCCTGGTGTGCTGCAGCCGGCTCTTCGAGGTGACGGATGTGAACAA
GCTGCAGAAGCAGGCAGCGCATCAGAGGGAGGTGTTCCTCTTCAATGACCTGCTGGTGATTCTCAAACTTTGCCCGAAGAAGAAGAGCTC
CTCCACGTACACCTTTTGCAAGTCAGTTGGCCTGCTGGGCATGCAGTTCCAGCTCTTTGAGAACGAGTATTACTCTCATGGCATCACACT
GGTGACCCCGCTCTCGGGCTCCGAGAAGAAGCAGGTGCTGCATTTCTGTGCCCTGGGCTCGGACGAGATGCAGAAGTTCGTGGAGGACCT
GAAGGAGTCCATTGCTGAGGTGACGGAGCTGGAGCAGATCCGAATAGAGTGGGAGCTGGAGAAGCAGCAGGGAACAAAGACACTCTCCTT
CAAGCCCTGCGGAGCCCAGGGGGACCCACAGTCAAAGCAAGGATCGCCGACAGCCAAAAGGGAAGCCGCGCTCAGGGAGAGGCCGGCGGA
GAGCACGGTGGAGGTGTCAATTCACAACAGGCTTCAAACGTCCCAGCACAACTCCGGGCTGGGGGCCGAGAGGGGAGCGCCGGTGCCGCC
GCCAGACCTGCAGCCTAGCCCCCCGAGACAGCAGACCCCACCACTGCCGCCGCCGCCACCCACGCCCCCGGGCACCCTGGTGCAGTGCCA
GCAAATTGTCAAGGTCATTGTCCTGGACAAGCCCTGCCTGGCCCGCATGGAGCCCCTGCTGAGCCAGGCTCTCTCCTGCTACACCTCGTC
GTCCTCTGACTCCTGCGGCTCCACACCCCTGGGCGGTCCCGGCTCTCCGGTCAAGGTCACCCACCAGCCTCCGCTGCCCCCGCCCCCACC
CCCCTACAACCACCCTCACCAGTTCTGTCCCCCAGGCTCCCTGCTGCACGGGCACCGCTACTCCAGTGGCTCAAGGAGCCTGGTGTAGAC
TCTGCCCCACCACCCTGCTGTCCTGGGAGGGCTGGCCACTGGGGGGCCTGGGCTGCCCCTCCACTGCTCCCCATACCCTGGCACGATGCG
TTCCTGGTCACTGATCACCATCATTTTGGGAAGAGAATCCCAATCCCTGGCACCTGGGTTTGCCTCATCCAACCATCCTTCCCTTTCTCA
GCTGCACCCCCTCTGCAGATCTGAAGACACACCTCACTCTCCCAGGGCCCTACACAGCCAGACCCGGCGAGGCCTCCTCTTCCCCTGGCC
ACCACTTTCCCCCATTGGACCATGGACTGAAGAAAACGAGCTGAGGGTCTAACGAGCTTGCAGGCTTTGAGTCTGTTAGTGCCCGGGGCC
TCGGGCCTTGGGCAGCAGCATGAGGCTGGGCCGGCCGGCAGTGGAGCACTAGACAGAGTGGCTGGCTCGCAGCCCAGAACTAGTGCCTCT
GTAGCTGCACTGAGGGGAGGAGGGTTGGTCCCACCCCTGGAGGGACAGGTGGGAGGAGTGAGGAGGGGGCTTTTTCTGCCACCCCCGCCC
CCAAGCCTGAAACTCTCAGGAGTCTACTTCTTGGTCCCCAGGGACATTGGCTGTCCTGACCATGTCCTTCCCCCTCCTCCCAGGGCCTCT
GCTTCCTCAGGAGCTGCCCAGACTCCAGAAAAGCCTGGAAAAAGGGAGGCGGGAAGGGGAGCACTTTCGGCTTTCTATAGGTCAGTCCAG
CAGGGCCACGGGATCGCGAGGTCATGTATCTGCAAAATGCACCTTTTTAAAGAGTGTCTTAGTTCCCCAGCCCCAGCTAATACCCGGCCA
ATGCCGTGTACGCACCGGCATGTGCACGCAAACACGCATGAGAACCAGGCCATTCCTTCCGCTGTGGAAGCAGAACTGGAGACGGGGCAG
GAATGTGCCCAGCAGAGATGGGGCTCAGCCCGAGGCAGGGCTCCCTCCTGCATGAGGCTCGGCCCGAGGCAGGGCTCCCTCCTGCATGAG
TCTGTGGCCTCCAGGAGGGACTTGGGTGCAGATGTAAGCAAGAAAAACCGGGGCTCCAGAGGCATGTGCATTTCCCCTGCGCCCCTCAGC
CTTTAAATATTCCCTCCTCCTAGAAGGTTCTAGACCCCCCCCTTCCAGCAGGGGTGCCCAAGAGTCCCTGGACCCTCAAAATTGCAAAGG
AGACCCAAGCGGGGCTCGCTGACCTCCCAGGGCCCAGCAAGATGGGATAGCCAGCCTTAGGTGGCCCCACGAGCCCAAGCCTGGGGAAGG
GCCCCTCCCCAGCCAGACGAGAGGCAGCCACCCCAGAGACCACAGGAGCCGTACCATGGCCTGCGCAGTCAGGCCCTATCAGGATGTGTC
TGTCCCAAGCCTGGCCAGGCTCCAGTCCTGTGCCAGTAGCTCACTGCTGTCCTATGTGCAGGTCCCCCAACACTTGGAGCCTGTGGTTAA
GGCCTCCTGGGAGAGGCAGTGAGCATGAGTCAAAGGTGACATGGACTTGAATCTCCCCACCCCGCCCCGCCTGCAGTAGCCGGGCCAGGT
AGGAGGCAAGGATCATTCCCTGCTCCCAGAGGTTCCAGATGACCTAGTTTCGTTTTGTGTGTGTGTGTGTGTGGTCACCCAGACGTCACT
GTGATATCACCTAGTGAATCTATTTCTGGCCCTGTCTTCGTCGGCCCAGTTTCTGTAACTTGCAGCCAATTTGCCCTCTCCCCTGTGGCT
GCCAGCCCATCTGCCCCTCTGTGTCCTTGCTGCCCTGGCCCTCCTCTGTTTTCTGTAACAGATGCTCCAGTCATTGCCTTTCAGAGTGGA
GCAGATGACAGATGGGGTGCACGCATTCAGACACCTCTGATGCCCTTAGCCAGGGCAGGGATCGTCCTTAAAGTGAAGGCCTGGACAGGA
GGAGTCAGGGACTTGGGAGGAGGTGGAGCTGTGGGGATGGGAGTGGAGGAATCAAAATGAGGGAAGCTGAAAATAGAATGAAAACGATGA
CTAAGAGGCAGGGAGTGCGAGGTATGGGGGAATAGGAACTATGAGCTAAATATACTTATGGGGTGGGGGCCGTGGGGGCCAGGGACACTC
TCCCAGACAGCCCTGACCCGCCAGGCAGGACCCCGTCCCCTGCTCACACAGCTCTTCAAACTTACCAAGGACAGGCAGGACCCCGTCCCC
TGCTCACACAGCTCTTCAAGCTTACCAAGGACAGGCAGAACCCCGTCCCCTGCTCACACAGCTCTTCAAGCTTACCAAGGACAGGCAGGA
CCCCGTCCCCTGCTCACACAGCTCTTCAAACTTACCAAGTGCCCTCTCCCCTGTTGAGGGCACAGCAACCCCAGGCCCTCCCTCCCACCT
CAGCTGAAGCCCCAATCTTCCAAATCGGAACCAGCAAGTCTTAGGGCTGGCACGCATCTGGGCCTCTAGCTGAGAACCCGGACTCTCAGG
CACCTCAGTGCCCCTGCCCCAGGGCAGAGGCCCACCCCGTGGGTTGGTGCAGTGGCTGCCCTGGGCTCCACGGGCAGCACAGGGAGTCTG
TCCAGGAAGCAGCCCAGCCGGGGTCAGTATTCCGTGGAGCCAGTCCTGAGCTGGGAGGGGCATTTAACACCCCTGAGGGCCTGGGGCAGG
ACACAGCTGGCCCTCCTCATTGTCAGGGGAAGCAAGTGCCCAACATCTGTAACCTCCCTTCCCTGCTCAGTCCCCAGGCCAAGGTTGGGA
CCCCTCTCCATCCCTGTCCCCAGAGCCTAGACCTCAGGGACCTAGGAAAAGCCTCCTGCTCCCTCCCCACGGCAGCAGACAGGGCAGGGC
CTCCAGCCCCCAGAGGGCCGGTGGGGGGTGCTCTCGGGCCTTCCTGCTCTCCTAAGGTTGCGGGGACAGTAGAGTGCTGAGCCCCAGACC
CAGTCACCCCAAGATGGCCCCACTCTATCCACTCTCTAGACCTTTGGGAAATCTGGGTCCCTCTCCTGATTTGATCCATTCGGCCCCAAC
TCCAGAGTCGGGAATGGGAGATGAAACTAGTTTTCCACCCACTTTTGGACAAGTCCCACCCCTAGATCTGAAGCAAGCTCTACCAGCAGC
GTGTCCTGGAAGCCTGCCTGCCTGCCTGCCCGTCTGCACAGGTGTCTTGATCCAGCCCTGCGTCTTCGAGCCCCTGTGCCACCGGTCCCC
ACGGCCCGCCAGGAGTCTCTTTGTACCCACTAGGCTTCCCTGATGACCATCTGTCTGTCCGTCCCTGTTTTTGCTGTACATAACTCCTGC
TGCACCCTCTCCCCGCACACCCGTCACCCATGAGAGAGAGAAACCTCTCTAGGGAAAGGCAGGGTGGCTGCACCCAGCAACTAATCCAAA
TGGCAAATATTTTGTAACAAAATAGCCCAGAGGTATTTTATCTGTTCAATTCATAGAGTTTTAGAGATTATATTGAAAGATGTCACTTGA

>99331_99331_2_WNK1-IQSEC3_WNK1_chr12_863490_ENST00000315939_IQSEC3_chr12_247432_ENST00000538872_length(amino acids)=1183AA_BP=300
MSVLSEASSGSARTRPAAVPCRPLRGRLGPSRPFRSRIRARSPLSSEPTMSGGAAEKQSSTPGSLFLSPPAPAPKNGSSSDSSVGEKLGA
AAADAVTGRTEEYRRRRHTMDKDSRGAAATTTTTEHRFFRRSVICDSNATALELPGLPLSLPQPSIPAAVPQSAPPEPHREETVTATATS
QVAQQPPAAAAPGEQAVAGPAPSTVPSSTSKDRPVSQPSLVGSKEEPPPARSGSGGGSAKEPQEERSQQQDDIEELETKAVGMSNDGRFL
KFDIEIGRGSFKTVYKGLDTETTVEVAWCELQIEMLEHKYGGHLVSRRAACTIQTAFRQYQLSKNFEKIRNSLLESRLPRRISLRKVRSP
TAESLAAEKALMEGYGLVGLPLVRSPSLPPTFAGTLTELEDSFTEQVQSLAKSIDDALSTWSLKTMCSLRESGAYQLHQALQAAAGPPGL
EAEGRAPESAGPGPGDDAAETPGLPPAHSGTLMMAFRDVTVQIANQNISVSSSTALSVANCLGAQTVQAPAEPAAGKAEQGETSGREAPE
APAVGREDASAEDSCAEAAASGAADGATAPKTEEEEEEEETAEVGRGAEAEAGDLEQLSSSSTSTKSAKSGSEASASASKDALQAMILSL
PRYHCENPASCKSPTLSTDTLRKRLYRIGLNLFNINPDKGIQFLISRGFIPDTPIGVAHFLLQRKGLSRQMIGEFLGNSKKQFNRDVLDC
VVDEMDFSSMELDEALRKFQAHIRVQGEAQKVERLIEAFSQRYCMCNPEVVQQFHNPDTIFILAFAIILLNTDMYSPNIKPDRKMMLEDF
IRNLRGVDDGADIPRELVVGIYERIQQKELKSNEDHVTYVTKVEKSIVGMKTVLSVPHRRLVCCSRLFEVTDVNKLQKQAAHQREVFLFN
DLLVILKLCPKKKSSSTYTFCKSVGLLGMQFQLFENEYYSHGITLVTPLSGSEKKQVLHFCALGSDEMQKFVEDLKESIAEVTELEQIRI
EWELEKQQGTKTLSFKPCGAQGDPQSKQGSPTAKREAALRERPAESTVEVSIHNRLQTSQHNSGLGAERGAPVPPPDLQPSPPRQQTPPL
PPPPPTPPGTLVQCQQIVKVIVLDKPCLARMEPLLSQALSCYTSSSSDSCGSTPLGGPGSPVKVTHQPPLPPPPPPYNHPHQFCPPGSLL

--------------------------------------------------------------
>99331_99331_3_WNK1-IQSEC3_WNK1_chr12_863490_ENST00000315939_IQSEC3_chr12_247433_ENST00000326261_length(transcript)=7362nt_BP=1402nt
CCGGCCCTTCGCCTCTGGGCGATGGGCGACCTGTGAGGCCGGTCCCCATCGCTGGGGGCGCGTGTGGGAGGAGGCGGCCGCCCGAGTGAC
CGGGAGCCGGGCCGCGGCCTTCCCTCGCCCGCCTCGGCCCCTCCCACTCCTCTGCCCCGGGGCCGCCACCGCCCGGGCGTCGGACCTGGT
CCCGTGCTCGCGGTGCCGCCGCCCTCTGGGCCTAGCCCGCCCAGCTCGGCGAGCGGCGGCAGTGGGAGCCGCGTCCGCCGCATCCGCCTC
GACTCGGTGCCGGCCCCTGGCCCTCCCCTCATGACTGCGGCGCCTCTGCTGCCACCGCCCGCCCGGCCGCCGCTCGCCGCAGGATGGATG
CGGACCGTGCGGCGCTAACCCCCGTGGCTCAGCTCCCGAATCGCCCGCCTTCGAGCCCTCCTCGTGAGCCGCAGCAGCCTCGGTGCCAGC
CCCCGCCGCAGCTGGGCCCAGCGGTCCGCCTGTCCCTCGTTGCGGCTTGTCGGTGCTGAGTGAGGCGTCGTCCGGGTCGGCGCGAACCCG
CCCGGCCGCGGTTCCCTGCAGACCTCTGCGCGGGCGGCTCGGCCCTTCACGCCCTTTTCGTTCACGAATCCGAGCCCGCTCGCCTCTCTC
CAGCGAACCGACCATGTCTGGCGGCGCCGCAGAGAAGCAGAGCAGCACTCCCGGTTCCCTGTTCCTCTCGCCGCCGGCTCCTGCCCCCAA
GAATGGCTCCAGCTCCGATTCCTCCGTGGGGGAGAAACTGGGAGCCGCGGCCGCCGACGCTGTGACCGGCAGGACCGAGGAGTACAGGCG
CCGCCGCCACACTATGGACAAGGACAGCCGTGGGGCGGCCGCGACCACTACCACCACTGAGCACCGCTTCTTCCGCCGGAGCGTCATCTG
TGACTCCAATGCCACTGCACTGGAGCTTCCCGGCCTTCCTCTTTCCCTGCCCCAGCCCAGCATCCCCGCGGCTGTCCCGCAGAGTGCTCC
ACCGGAGCCCCACCGGGAAGAGACCGTGACCGCCACCGCCACTTCCCAGGTAGCCCAGCAGCCTCCAGCCGCTGCCGCCCCTGGGGAACA
GGCCGTCGCGGGCCCTGCCCCCTCGACTGTCCCCAGCAGTACCAGCAAAGACCGCCCAGTGTCCCAGCCTAGCCTTGTGGGGAGCAAAGA
GGAGCCGCCGCCGGCGAGAAGTGGCAGCGGCGGCGGCAGCGCCAAGGAGCCACAGGAGGAACGGAGCCAGCAGCAGGATGATATCGAAGA
GCTGGAGACCAAGGCCGTGGGAATGTCTAACGATGGCCGCTTTCTCAAGTTTGACATCGAAATCGGCAGAGGCTCCTTTAAGACGGTCTA
CAAAGGTCTGGACACTGAAACCACCGTGGAAGTCGCCTGGTGTGAACTGCAGATTGAAATGCTAGAACATAAGTACGGCGGTCACCTGGT
GTCCCGGCGCGCCGCTTGCACCATCCAAACCGCCTTCCGCCAATACCAGCTCAGCAAGAACTTCGAGAAAATCCGCAACTCGCTTCTGGA
GAGCCGCCTGCCACGGCGGATCTCCCTGCGCAAGGTGCGGTCACCCACGGCCGAGAGCCTGGCGGCCGAGAAAGCGCTCATGGAGGGCTA
CGGCCTCGTGGGGCTGCCGCTGGTGCGCTCGCCCTCCCTGCCGCCCACCTTCGCAGGCACCCTCACCGAGCTGGAGGACTCCTTCACCGA
GCAGGTGCAATCCCTGGCCAAGTCCATCGACGACGCGCTCAGCACGTGGAGCCTCAAGACCATGTGCTCCCTGCGGGAGAGTGGCGCTTA
CCAGCTCCACCAGGCCCTGCAGGCGGCCGCGGGGCCCCCAGGCCTGGAGGCCGAGGGGCGGGCGCCGGAGAGCGCGGGCCCCGGGCCCGG
GGATGACGCCGCGGAGACCCCCGGCCTGCCCCCGGCCCACAGCGGGACCCTCATGATGGCTTTCCGGGACGTCACGGTGCAGATCGCCAA
CCAGAACATATCCGTCTCCTCCTCCACGGCTCTGTCGGTGGCCAACTGCCTGGGCGCTCAGACGGTCCAGGCCCCCGCAGAGCCCGCGGC
GGGCAAGGCCGAGCAGGGCGAGACCTCTGGGCGGGAGGCCCCGGAAGCCCCCGCCGTGGGCCGGGAGGACGCGTCAGCCGAGGACTCATG
CGCAGAGGCTGCGGCTAGTGGGGCGGCGGATGGGGCCACAGCCCCCAAAACAGAGGAGGAAGAGGAGGAGGAGGAGACGGCGGAGGTGGG
GAGAGGGGCCGAGGCCGAGGCAGGCGACTTGGAGCAGCTGAGCAGCAGCAGCACGTCCACCAAGTCCGCCAAGTCAGGCTCGGAGGCGTC
GGCCTCCGCCTCCAAGGACGCCCTGCAGGCCATGATCCTGAGCCTGCCGCGCTACCACTGCGAGAACCCAGCCAGCTGCAAGTCGCCCAC
GCTCTCCACCGACACCCTGCGCAAGCGGCTCTACCGCATCGGCCTCAACCTCTTCAACATAAACCCCGACAAGGGCATCCAGTTCCTGAT
CTCACGCGGCTTCATCCCGGACACCCCCATCGGTGTGGCCCATTTCCTCCTCCAGCGAAAGGGCCTCAGCCGCCAGATGATTGGAGAGTT
CCTGGGCAACAGCAAGAAGCAGTTCAACCGCGACGTGCTGGACTGCGTGGTGGACGAGATGGACTTCTCCAGCATGGAGCTGGACGAGGC
CCTGCGCAAGTTCCAGGCACACATCCGTGTGCAGGGGGAGGCTCAGAAGGTGGAGCGGCTCATTGAGGCCTTCAGCCAGCGCTACTGCAT
GTGCAACCCCGAAGTGGTTCAGCAGTTCCACAACCCCGACACCATCTTCATCCTCGCCTTCGCCATCATCCTCCTCAACACCGACATGTA
CAGCCCCAACATCAAGCCTGACCGGAAGATGATGCTGGAGGACTTCATCCGAAACCTTCGAGGTGTGGACGATGGCGCTGACATCCCCAG
GGAGCTGGTGGTAGGCATCTATGAGAGGATACAGCAGAAGGAGCTCAAGTCCAATGAGGACCACGTCACGTACGTCACCAAGGTGGAGAA
GTCCATTGTGGGCATGAAGACAGTGCTGTCCGTGCCCCACCGCCGCCTGGTGTGCTGCAGCCGGCTCTTCGAGGTGACGGATGTGAACAA
GCTGCAGAAGCAGGCAGCGCATCAGAGGGAGGTGTTCCTCTTCAATGACCTGCTGGTGATTCTCAAACTTTGCCCGAAGAAGAAGAGCTC
CTCCACGTACACCTTTTGCAAGTCAGTTGGCCTGCTGGGCATGCAGTTCCAGCTCTTTGAGAACGAGTATTACTCTCATGGCATCACACT
GGTGACCCCGCTCTCGGGCTCCGAGAAGAAGCAGGTGCTGCATTTCTGTGCCCTGGGCTCGGACGAGATGCAGAAGTTCGTGGAGGACCT
GAAGGAGTCCATTGCTGAGGTGACGGAGCTGGAGCAGATCCGAATAGAGTGGGAGCTGGAGAAGCAGCAGGGAACAAAGACACTCTCCTT
CAAGCCCTGCGGAGCCCAGGGGGACCCACAGTCAAAGCAAGGATCGCCGACAGCCAAAAGGGAAGCCGCGCTCAGGGAGAGGCCGGCGGA
GAGCACGGTGGAGGTGTCAATTCACAACAGGCTTCAAACGTCCCAGCACAACTCCGGGCTGGGGGCCGAGAGGGGAGCGCCGGTGCCGCC
GCCAGACCTGCAGCCTAGCCCCCCGAGACAGCAGACCCCACCACTGCCGCCGCCGCCACCCACGCCCCCGGGCACCCTGGTGCAGTGCCA
GCAAATTGTCAAGGTCATTGTCCTGGACAAGCCCTGCCTGGCCCGCATGGAGCCCCTGCTGAGCCAGGCTCTCTCCTGCTACACCTCGTC
GTCCTCTGACTCCTGCGGCTCCACACCCCTGGGCGGTCCCGGCTCTCCGGTCAAGGTCACCCACCAGCCTCCGCTGCCCCCGCCCCCACC
CCCCTACAACCACCCTCACCAGTTCTGTCCCCCAGGCTCCCTGCTGCACGGGCACCGCTACTCCAGTGGCTCAAGGAGCCTGGTGTAGAC
TCTGCCCCACCACCCTGCTGTCCTGGGAGGGCTGGCCACTGGGGGGCCTGGGCTGCCCCTCCACTGCTCCCCATACCCTGGCACGATGCG
TTCCTGGTCACTGATCACCATCATTTTGGGAAGAGAATCCCAATCCCTGGCACCTGGGTTTGCCTCATCCAACCATCCTTCCCTTTCTCA
GCTGCACCCCCTCTGCAGATCTGAAGACACACCTCACTCTCCCAGGGCCCTACACAGCCAGACCCGGCGAGGCCTCCTCTTCCCCTGGCC
ACCACTTTCCCCCATTGGACCATGGACTGAAGAAAACGAGCTGAGGGTCTAACGAGCTTGCAGGCTTTGAGTCTGTTAGTGCCCGGGGCC
TCGGGCCTTGGGCAGCAGCATGAGGCTGGGCCGGCCGGCAGTGGAGCACTAGACAGAGTGGCTGGCTCGCAGCCCAGAACTAGTGCCTCT
GTAGCTGCACTGAGGGGAGGAGGGTTGGTCCCACCCCTGGAGGGACAGGTGGGAGGAGTGAGGAGGGGGCTTTTTCTGCCACCCCCGCCC
CCAAGCCTGAAACTCTCAGGAGTCTACTTCTTGGTCCCCAGGGACATTGGCTGTCCTGACCATGTCCTTCCCCCTCCTCCCAGGGCCTCT
GCTTCCTCAGGAGCTGCCCAGACTCCAGAAAAGCCTGGAAAAAGGGAGGCGGGAAGGGGAGCACTTTCGGCTTTCTATAGGTCAGTCCAG
CAGGGCCACGGGATCGCGAGGTCATGTATCTGCAAAATGCACCTTTTTAAAGAGTGTCTTAGTTCCCCAGCCCCAGCTAATACCCGGCCA
ATGCCGTGTACGCACCGGCATGTGCACGCAAACACGCATGAGAACCAGGCCATTCCTTCCGCTGTGGAAGCAGAACTGGAGACGGGGCAG
GAATGTGCCCAGCAGAGATGGGGCTCAGCCCGAGGCAGGGCTCCCTCCTGCATGAGGCTCGGCCCGAGGCAGGGCTCCCTCCTGCATGAG
TCTGTGGCCTCCAGGAGGGACTTGGGTGCAGATGTAAGCAAGAAAAACCGGGGCTCCAGAGGCATGTGCATTTCCCCTGCGCCCCTCAGC
CTTTAAATATTCCCTCCTCCTAGAAGGTTCTAGACCCCCCCCTTCCAGCAGGGGTGCCCAAGAGTCCCTGGACCCTCAAAATTGCAAAGG
AGACCCAAGCGGGGCTCGCTGACCTCCCAGGGCCCAGCAAGATGGGATAGCCAGCCTTAGGTGGCCCCACGAGCCCAAGCCTGGGGAAGG
GCCCCTCCCCAGCCAGACGAGAGGCAGCCACCCCAGAGACCACAGGAGCCGTACCATGGCCTGCGCAGTCAGGCCCTATCAGGATGTGTC
TGTCCCAAGCCTGGCCAGGCTCCAGTCCTGTGCCAGTAGCTCACTGCTGTCCTATGTGCAGGTCCCCCAACACTTGGAGCCTGTGGTTAA
GGCCTCCTGGGAGAGGCAGTGAGCATGAGTCAAAGGTGACATGGACTTGAATCTCCCCACCCCGCCCCGCCTGCAGTAGCCGGGCCAGGT
AGGAGGCAAGGATCATTCCCTGCTCCCAGAGGTTCCAGATGACCTAGTTTCGTTTTGTGTGTGTGTGTGTGTGGTCACCCAGACGTCACT
GTGATATCACCTAGTGAATCTATTTCTGGCCCTGTCTTCGTCGGCCCAGTTTCTGTAACTTGCAGCCAATTTGCCCTCTCCCCTGTGGCT
GCCAGCCCATCTGCCCCTCTGTGTCCTTGCTGCCCTGGCCCTCCTCTGTTTTCTGTAACAGATGCTCCAGTCATTGCCTTTCAGAGTGGA
GCAGATGACAGATGGGGTGCACGCATTCAGACACCTCTGATGCCCTTAGCCAGGGCAGGGATCGTCCTTAAAGTGAAGGCCTGGACAGGA
GGAGTCAGGGACTTGGGAGGAGGTGGAGCTGTGGGGATGGGAGTGGAGGAATCAAAATGAGGGAAGCTGAAAATAGAATGAAAACGATGA
CTAAGAGGCAGGGAGTGCGAGGTATGGGGGAATAGGAACTATGAGCTAAATATACTTATGGGGTGGGGGCCGTGGGGGCCAGGGACACTC
TCCCAGACAGCCCTGACCCGCCAGGCAGGACCCCGTCCCCTGCTCACACAGCTCTTCAAACTTACCAAGGACAGGCAGGACCCCGTCCCC
TGCTCACACAGCTCTTCAAGCTTACCAAGTCCCCTGTTGAGGGCACAGCAACCCCAGGCCCTCCCTCCCACCTCAGCTGAAGCCCCAATC
TTCCAAATCGGAACCAGCAAGTCTTAGGGCTGGCACGCATCTGGGCCTCTAGCTGAGAACCCGGACTCTCAGGCACCTCAGTGCCCCTGC
CCCAGGGCAGAGGCCCACCCCGTGGGTTGGTGCAGTGGCTGCCCTGGGCTCCACGGGCAGCACAGGGAGTCTGTCCAGGAAGCAGCCCAG
CCGGGGTCAGTATTCCGTGGAGCCAGTCCTGAGCTGGGAGGGGCATTTAACACCCCTGAGGGCCTGGGGCAGGACACAGCTGGCCCTCCT
CATTGTCAGGGGAAGCAAGTGCCCAACATCTGTAACCTCCCTTCCCTGCTCAGTCCCCAGGCCAAGGTTGGGACCCCTCTCCATCCCTGT
CCCCAGAGCCTAGACCTCAGGGACCTAGGAAAAGCCTCCTGCTCCCTCCCCACGGCAGCAGACAGGGCAGGGCCTCCAGCCCCCAGAGGG
CCGGTGGGGGGTGCTCTCGGGCCTTCCTGCTCTCCTAAGGTTGCGGGGACAGTAGAGTGCTGAGCCCCAGACCCAGTCACCCCAAGATGG
CCCCACTCTATCCACTCTCTAGACCTTTGGGAAATCTGGGTCCCTCTCCTGATTTGATCCATTCGGCCCCAACTCCAGAGTCGGGAATGG
GAGATGAAACTAGTTTTCCACCCACTTTTGGACAAGTCCCACCCCTAGATCTGAAGCAAGCTCTACCAGCAGCGTGTCCTGGAAGCCTGC
CTGCCTGCCTGCCCGTCTGCACAGGTGTCTTGATCCAGCCCTGCGTCTTCGAGCCCCTGTGCCACCGGTCCCCACGGCCCGCCAGGAGTC
TCTTTGTACCCACTAGGCTTCCCTGATGACCATCTGTCTGTCCGTCCCTGTTTTTGCTGTACATAACTCCTGCTGCACCCTCTCCCCGCA
CACCCGTCACCCATGAGAGAGAGAAACCTCTCTAGGGAAAGGCAGGGTGGCTGCACCCAGCAACTAATCCAAATGGCAAATATTTTGTAA

>99331_99331_3_WNK1-IQSEC3_WNK1_chr12_863490_ENST00000315939_IQSEC3_chr12_247433_ENST00000326261_length(amino acids)=1183AA_BP=300
MSVLSEASSGSARTRPAAVPCRPLRGRLGPSRPFRSRIRARSPLSSEPTMSGGAAEKQSSTPGSLFLSPPAPAPKNGSSSDSSVGEKLGA
AAADAVTGRTEEYRRRRHTMDKDSRGAAATTTTTEHRFFRRSVICDSNATALELPGLPLSLPQPSIPAAVPQSAPPEPHREETVTATATS
QVAQQPPAAAAPGEQAVAGPAPSTVPSSTSKDRPVSQPSLVGSKEEPPPARSGSGGGSAKEPQEERSQQQDDIEELETKAVGMSNDGRFL
KFDIEIGRGSFKTVYKGLDTETTVEVAWCELQIEMLEHKYGGHLVSRRAACTIQTAFRQYQLSKNFEKIRNSLLESRLPRRISLRKVRSP
TAESLAAEKALMEGYGLVGLPLVRSPSLPPTFAGTLTELEDSFTEQVQSLAKSIDDALSTWSLKTMCSLRESGAYQLHQALQAAAGPPGL
EAEGRAPESAGPGPGDDAAETPGLPPAHSGTLMMAFRDVTVQIANQNISVSSSTALSVANCLGAQTVQAPAEPAAGKAEQGETSGREAPE
APAVGREDASAEDSCAEAAASGAADGATAPKTEEEEEEEETAEVGRGAEAEAGDLEQLSSSSTSTKSAKSGSEASASASKDALQAMILSL
PRYHCENPASCKSPTLSTDTLRKRLYRIGLNLFNINPDKGIQFLISRGFIPDTPIGVAHFLLQRKGLSRQMIGEFLGNSKKQFNRDVLDC
VVDEMDFSSMELDEALRKFQAHIRVQGEAQKVERLIEAFSQRYCMCNPEVVQQFHNPDTIFILAFAIILLNTDMYSPNIKPDRKMMLEDF
IRNLRGVDDGADIPRELVVGIYERIQQKELKSNEDHVTYVTKVEKSIVGMKTVLSVPHRRLVCCSRLFEVTDVNKLQKQAAHQREVFLFN
DLLVILKLCPKKKSSSTYTFCKSVGLLGMQFQLFENEYYSHGITLVTPLSGSEKKQVLHFCALGSDEMQKFVEDLKESIAEVTELEQIRI
EWELEKQQGTKTLSFKPCGAQGDPQSKQGSPTAKREAALRERPAESTVEVSIHNRLQTSQHNSGLGAERGAPVPPPDLQPSPPRQQTPPL
PPPPPTPPGTLVQCQQIVKVIVLDKPCLARMEPLLSQALSCYTSSSSDSCGSTPLGGPGSPVKVTHQPPLPPPPPPYNHPHQFCPPGSLL

--------------------------------------------------------------
>99331_99331_4_WNK1-IQSEC3_WNK1_chr12_863490_ENST00000315939_IQSEC3_chr12_247433_ENST00000538872_length(transcript)=7475nt_BP=1402nt
CCGGCCCTTCGCCTCTGGGCGATGGGCGACCTGTGAGGCCGGTCCCCATCGCTGGGGGCGCGTGTGGGAGGAGGCGGCCGCCCGAGTGAC
CGGGAGCCGGGCCGCGGCCTTCCCTCGCCCGCCTCGGCCCCTCCCACTCCTCTGCCCCGGGGCCGCCACCGCCCGGGCGTCGGACCTGGT
CCCGTGCTCGCGGTGCCGCCGCCCTCTGGGCCTAGCCCGCCCAGCTCGGCGAGCGGCGGCAGTGGGAGCCGCGTCCGCCGCATCCGCCTC
GACTCGGTGCCGGCCCCTGGCCCTCCCCTCATGACTGCGGCGCCTCTGCTGCCACCGCCCGCCCGGCCGCCGCTCGCCGCAGGATGGATG
CGGACCGTGCGGCGCTAACCCCCGTGGCTCAGCTCCCGAATCGCCCGCCTTCGAGCCCTCCTCGTGAGCCGCAGCAGCCTCGGTGCCAGC
CCCCGCCGCAGCTGGGCCCAGCGGTCCGCCTGTCCCTCGTTGCGGCTTGTCGGTGCTGAGTGAGGCGTCGTCCGGGTCGGCGCGAACCCG
CCCGGCCGCGGTTCCCTGCAGACCTCTGCGCGGGCGGCTCGGCCCTTCACGCCCTTTTCGTTCACGAATCCGAGCCCGCTCGCCTCTCTC
CAGCGAACCGACCATGTCTGGCGGCGCCGCAGAGAAGCAGAGCAGCACTCCCGGTTCCCTGTTCCTCTCGCCGCCGGCTCCTGCCCCCAA
GAATGGCTCCAGCTCCGATTCCTCCGTGGGGGAGAAACTGGGAGCCGCGGCCGCCGACGCTGTGACCGGCAGGACCGAGGAGTACAGGCG
CCGCCGCCACACTATGGACAAGGACAGCCGTGGGGCGGCCGCGACCACTACCACCACTGAGCACCGCTTCTTCCGCCGGAGCGTCATCTG
TGACTCCAATGCCACTGCACTGGAGCTTCCCGGCCTTCCTCTTTCCCTGCCCCAGCCCAGCATCCCCGCGGCTGTCCCGCAGAGTGCTCC
ACCGGAGCCCCACCGGGAAGAGACCGTGACCGCCACCGCCACTTCCCAGGTAGCCCAGCAGCCTCCAGCCGCTGCCGCCCCTGGGGAACA
GGCCGTCGCGGGCCCTGCCCCCTCGACTGTCCCCAGCAGTACCAGCAAAGACCGCCCAGTGTCCCAGCCTAGCCTTGTGGGGAGCAAAGA
GGAGCCGCCGCCGGCGAGAAGTGGCAGCGGCGGCGGCAGCGCCAAGGAGCCACAGGAGGAACGGAGCCAGCAGCAGGATGATATCGAAGA
GCTGGAGACCAAGGCCGTGGGAATGTCTAACGATGGCCGCTTTCTCAAGTTTGACATCGAAATCGGCAGAGGCTCCTTTAAGACGGTCTA
CAAAGGTCTGGACACTGAAACCACCGTGGAAGTCGCCTGGTGTGAACTGCAGATTGAAATGCTAGAACATAAGTACGGCGGTCACCTGGT
GTCCCGGCGCGCCGCTTGCACCATCCAAACCGCCTTCCGCCAATACCAGCTCAGCAAGAACTTCGAGAAAATCCGCAACTCGCTTCTGGA
GAGCCGCCTGCCACGGCGGATCTCCCTGCGCAAGGTGCGGTCACCCACGGCCGAGAGCCTGGCGGCCGAGAAAGCGCTCATGGAGGGCTA
CGGCCTCGTGGGGCTGCCGCTGGTGCGCTCGCCCTCCCTGCCGCCCACCTTCGCAGGCACCCTCACCGAGCTGGAGGACTCCTTCACCGA
GCAGGTGCAATCCCTGGCCAAGTCCATCGACGACGCGCTCAGCACGTGGAGCCTCAAGACCATGTGCTCCCTGCGGGAGAGTGGCGCTTA
CCAGCTCCACCAGGCCCTGCAGGCGGCCGCGGGGCCCCCAGGCCTGGAGGCCGAGGGGCGGGCGCCGGAGAGCGCGGGCCCCGGGCCCGG
GGATGACGCCGCGGAGACCCCCGGCCTGCCCCCGGCCCACAGCGGGACCCTCATGATGGCTTTCCGGGACGTCACGGTGCAGATCGCCAA
CCAGAACATATCCGTCTCCTCCTCCACGGCTCTGTCGGTGGCCAACTGCCTGGGCGCTCAGACGGTCCAGGCCCCCGCAGAGCCCGCGGC
GGGCAAGGCCGAGCAGGGCGAGACCTCTGGGCGGGAGGCCCCGGAAGCCCCCGCCGTGGGCCGGGAGGACGCGTCAGCCGAGGACTCATG
CGCAGAGGCTGCGGCTAGTGGGGCGGCGGATGGGGCCACAGCCCCCAAAACAGAGGAGGAAGAGGAGGAGGAGGAGACGGCGGAGGTGGG
GAGAGGGGCCGAGGCCGAGGCAGGCGACTTGGAGCAGCTGAGCAGCAGCAGCACGTCCACCAAGTCCGCCAAGTCAGGCTCGGAGGCGTC
GGCCTCCGCCTCCAAGGACGCCCTGCAGGCCATGATCCTGAGCCTGCCGCGCTACCACTGCGAGAACCCAGCCAGCTGCAAGTCGCCCAC
GCTCTCCACCGACACCCTGCGCAAGCGGCTCTACCGCATCGGCCTCAACCTCTTCAACATAAACCCCGACAAGGGCATCCAGTTCCTGAT
CTCACGCGGCTTCATCCCGGACACCCCCATCGGTGTGGCCCATTTCCTCCTCCAGCGAAAGGGCCTCAGCCGCCAGATGATTGGAGAGTT
CCTGGGCAACAGCAAGAAGCAGTTCAACCGCGACGTGCTGGACTGCGTGGTGGACGAGATGGACTTCTCCAGCATGGAGCTGGACGAGGC
CCTGCGCAAGTTCCAGGCACACATCCGTGTGCAGGGGGAGGCTCAGAAGGTGGAGCGGCTCATTGAGGCCTTCAGCCAGCGCTACTGCAT
GTGCAACCCCGAAGTGGTTCAGCAGTTCCACAACCCCGACACCATCTTCATCCTCGCCTTCGCCATCATCCTCCTCAACACCGACATGTA
CAGCCCCAACATCAAGCCTGACCGGAAGATGATGCTGGAGGACTTCATCCGAAACCTTCGAGGTGTGGACGATGGCGCTGACATCCCCAG
GGAGCTGGTGGTAGGCATCTATGAGAGGATACAGCAGAAGGAGCTCAAGTCCAATGAGGACCACGTCACGTACGTCACCAAGGTGGAGAA
GTCCATTGTGGGCATGAAGACAGTGCTGTCCGTGCCCCACCGCCGCCTGGTGTGCTGCAGCCGGCTCTTCGAGGTGACGGATGTGAACAA
GCTGCAGAAGCAGGCAGCGCATCAGAGGGAGGTGTTCCTCTTCAATGACCTGCTGGTGATTCTCAAACTTTGCCCGAAGAAGAAGAGCTC
CTCCACGTACACCTTTTGCAAGTCAGTTGGCCTGCTGGGCATGCAGTTCCAGCTCTTTGAGAACGAGTATTACTCTCATGGCATCACACT
GGTGACCCCGCTCTCGGGCTCCGAGAAGAAGCAGGTGCTGCATTTCTGTGCCCTGGGCTCGGACGAGATGCAGAAGTTCGTGGAGGACCT
GAAGGAGTCCATTGCTGAGGTGACGGAGCTGGAGCAGATCCGAATAGAGTGGGAGCTGGAGAAGCAGCAGGGAACAAAGACACTCTCCTT
CAAGCCCTGCGGAGCCCAGGGGGACCCACAGTCAAAGCAAGGATCGCCGACAGCCAAAAGGGAAGCCGCGCTCAGGGAGAGGCCGGCGGA
GAGCACGGTGGAGGTGTCAATTCACAACAGGCTTCAAACGTCCCAGCACAACTCCGGGCTGGGGGCCGAGAGGGGAGCGCCGGTGCCGCC
GCCAGACCTGCAGCCTAGCCCCCCGAGACAGCAGACCCCACCACTGCCGCCGCCGCCACCCACGCCCCCGGGCACCCTGGTGCAGTGCCA
GCAAATTGTCAAGGTCATTGTCCTGGACAAGCCCTGCCTGGCCCGCATGGAGCCCCTGCTGAGCCAGGCTCTCTCCTGCTACACCTCGTC
GTCCTCTGACTCCTGCGGCTCCACACCCCTGGGCGGTCCCGGCTCTCCGGTCAAGGTCACCCACCAGCCTCCGCTGCCCCCGCCCCCACC
CCCCTACAACCACCCTCACCAGTTCTGTCCCCCAGGCTCCCTGCTGCACGGGCACCGCTACTCCAGTGGCTCAAGGAGCCTGGTGTAGAC
TCTGCCCCACCACCCTGCTGTCCTGGGAGGGCTGGCCACTGGGGGGCCTGGGCTGCCCCTCCACTGCTCCCCATACCCTGGCACGATGCG
TTCCTGGTCACTGATCACCATCATTTTGGGAAGAGAATCCCAATCCCTGGCACCTGGGTTTGCCTCATCCAACCATCCTTCCCTTTCTCA
GCTGCACCCCCTCTGCAGATCTGAAGACACACCTCACTCTCCCAGGGCCCTACACAGCCAGACCCGGCGAGGCCTCCTCTTCCCCTGGCC
ACCACTTTCCCCCATTGGACCATGGACTGAAGAAAACGAGCTGAGGGTCTAACGAGCTTGCAGGCTTTGAGTCTGTTAGTGCCCGGGGCC
TCGGGCCTTGGGCAGCAGCATGAGGCTGGGCCGGCCGGCAGTGGAGCACTAGACAGAGTGGCTGGCTCGCAGCCCAGAACTAGTGCCTCT
GTAGCTGCACTGAGGGGAGGAGGGTTGGTCCCACCCCTGGAGGGACAGGTGGGAGGAGTGAGGAGGGGGCTTTTTCTGCCACCCCCGCCC
CCAAGCCTGAAACTCTCAGGAGTCTACTTCTTGGTCCCCAGGGACATTGGCTGTCCTGACCATGTCCTTCCCCCTCCTCCCAGGGCCTCT
GCTTCCTCAGGAGCTGCCCAGACTCCAGAAAAGCCTGGAAAAAGGGAGGCGGGAAGGGGAGCACTTTCGGCTTTCTATAGGTCAGTCCAG
CAGGGCCACGGGATCGCGAGGTCATGTATCTGCAAAATGCACCTTTTTAAAGAGTGTCTTAGTTCCCCAGCCCCAGCTAATACCCGGCCA
ATGCCGTGTACGCACCGGCATGTGCACGCAAACACGCATGAGAACCAGGCCATTCCTTCCGCTGTGGAAGCAGAACTGGAGACGGGGCAG
GAATGTGCCCAGCAGAGATGGGGCTCAGCCCGAGGCAGGGCTCCCTCCTGCATGAGGCTCGGCCCGAGGCAGGGCTCCCTCCTGCATGAG
TCTGTGGCCTCCAGGAGGGACTTGGGTGCAGATGTAAGCAAGAAAAACCGGGGCTCCAGAGGCATGTGCATTTCCCCTGCGCCCCTCAGC
CTTTAAATATTCCCTCCTCCTAGAAGGTTCTAGACCCCCCCCTTCCAGCAGGGGTGCCCAAGAGTCCCTGGACCCTCAAAATTGCAAAGG
AGACCCAAGCGGGGCTCGCTGACCTCCCAGGGCCCAGCAAGATGGGATAGCCAGCCTTAGGTGGCCCCACGAGCCCAAGCCTGGGGAAGG
GCCCCTCCCCAGCCAGACGAGAGGCAGCCACCCCAGAGACCACAGGAGCCGTACCATGGCCTGCGCAGTCAGGCCCTATCAGGATGTGTC
TGTCCCAAGCCTGGCCAGGCTCCAGTCCTGTGCCAGTAGCTCACTGCTGTCCTATGTGCAGGTCCCCCAACACTTGGAGCCTGTGGTTAA
GGCCTCCTGGGAGAGGCAGTGAGCATGAGTCAAAGGTGACATGGACTTGAATCTCCCCACCCCGCCCCGCCTGCAGTAGCCGGGCCAGGT
AGGAGGCAAGGATCATTCCCTGCTCCCAGAGGTTCCAGATGACCTAGTTTCGTTTTGTGTGTGTGTGTGTGTGGTCACCCAGACGTCACT
GTGATATCACCTAGTGAATCTATTTCTGGCCCTGTCTTCGTCGGCCCAGTTTCTGTAACTTGCAGCCAATTTGCCCTCTCCCCTGTGGCT
GCCAGCCCATCTGCCCCTCTGTGTCCTTGCTGCCCTGGCCCTCCTCTGTTTTCTGTAACAGATGCTCCAGTCATTGCCTTTCAGAGTGGA
GCAGATGACAGATGGGGTGCACGCATTCAGACACCTCTGATGCCCTTAGCCAGGGCAGGGATCGTCCTTAAAGTGAAGGCCTGGACAGGA
GGAGTCAGGGACTTGGGAGGAGGTGGAGCTGTGGGGATGGGAGTGGAGGAATCAAAATGAGGGAAGCTGAAAATAGAATGAAAACGATGA
CTAAGAGGCAGGGAGTGCGAGGTATGGGGGAATAGGAACTATGAGCTAAATATACTTATGGGGTGGGGGCCGTGGGGGCCAGGGACACTC
TCCCAGACAGCCCTGACCCGCCAGGCAGGACCCCGTCCCCTGCTCACACAGCTCTTCAAACTTACCAAGGACAGGCAGGACCCCGTCCCC
TGCTCACACAGCTCTTCAAGCTTACCAAGGACAGGCAGAACCCCGTCCCCTGCTCACACAGCTCTTCAAGCTTACCAAGGACAGGCAGGA
CCCCGTCCCCTGCTCACACAGCTCTTCAAACTTACCAAGTGCCCTCTCCCCTGTTGAGGGCACAGCAACCCCAGGCCCTCCCTCCCACCT
CAGCTGAAGCCCCAATCTTCCAAATCGGAACCAGCAAGTCTTAGGGCTGGCACGCATCTGGGCCTCTAGCTGAGAACCCGGACTCTCAGG
CACCTCAGTGCCCCTGCCCCAGGGCAGAGGCCCACCCCGTGGGTTGGTGCAGTGGCTGCCCTGGGCTCCACGGGCAGCACAGGGAGTCTG
TCCAGGAAGCAGCCCAGCCGGGGTCAGTATTCCGTGGAGCCAGTCCTGAGCTGGGAGGGGCATTTAACACCCCTGAGGGCCTGGGGCAGG
ACACAGCTGGCCCTCCTCATTGTCAGGGGAAGCAAGTGCCCAACATCTGTAACCTCCCTTCCCTGCTCAGTCCCCAGGCCAAGGTTGGGA
CCCCTCTCCATCCCTGTCCCCAGAGCCTAGACCTCAGGGACCTAGGAAAAGCCTCCTGCTCCCTCCCCACGGCAGCAGACAGGGCAGGGC
CTCCAGCCCCCAGAGGGCCGGTGGGGGGTGCTCTCGGGCCTTCCTGCTCTCCTAAGGTTGCGGGGACAGTAGAGTGCTGAGCCCCAGACC
CAGTCACCCCAAGATGGCCCCACTCTATCCACTCTCTAGACCTTTGGGAAATCTGGGTCCCTCTCCTGATTTGATCCATTCGGCCCCAAC
TCCAGAGTCGGGAATGGGAGATGAAACTAGTTTTCCACCCACTTTTGGACAAGTCCCACCCCTAGATCTGAAGCAAGCTCTACCAGCAGC
GTGTCCTGGAAGCCTGCCTGCCTGCCTGCCCGTCTGCACAGGTGTCTTGATCCAGCCCTGCGTCTTCGAGCCCCTGTGCCACCGGTCCCC
ACGGCCCGCCAGGAGTCTCTTTGTACCCACTAGGCTTCCCTGATGACCATCTGTCTGTCCGTCCCTGTTTTTGCTGTACATAACTCCTGC
TGCACCCTCTCCCCGCACACCCGTCACCCATGAGAGAGAGAAACCTCTCTAGGGAAAGGCAGGGTGGCTGCACCCAGCAACTAATCCAAA
TGGCAAATATTTTGTAACAAAATAGCCCAGAGGTATTTTATCTGTTCAATTCATAGAGTTTTAGAGATTATATTGAAAGATGTCACTTGA

>99331_99331_4_WNK1-IQSEC3_WNK1_chr12_863490_ENST00000315939_IQSEC3_chr12_247433_ENST00000538872_length(amino acids)=1183AA_BP=300
MSVLSEASSGSARTRPAAVPCRPLRGRLGPSRPFRSRIRARSPLSSEPTMSGGAAEKQSSTPGSLFLSPPAPAPKNGSSSDSSVGEKLGA
AAADAVTGRTEEYRRRRHTMDKDSRGAAATTTTTEHRFFRRSVICDSNATALELPGLPLSLPQPSIPAAVPQSAPPEPHREETVTATATS
QVAQQPPAAAAPGEQAVAGPAPSTVPSSTSKDRPVSQPSLVGSKEEPPPARSGSGGGSAKEPQEERSQQQDDIEELETKAVGMSNDGRFL
KFDIEIGRGSFKTVYKGLDTETTVEVAWCELQIEMLEHKYGGHLVSRRAACTIQTAFRQYQLSKNFEKIRNSLLESRLPRRISLRKVRSP
TAESLAAEKALMEGYGLVGLPLVRSPSLPPTFAGTLTELEDSFTEQVQSLAKSIDDALSTWSLKTMCSLRESGAYQLHQALQAAAGPPGL
EAEGRAPESAGPGPGDDAAETPGLPPAHSGTLMMAFRDVTVQIANQNISVSSSTALSVANCLGAQTVQAPAEPAAGKAEQGETSGREAPE
APAVGREDASAEDSCAEAAASGAADGATAPKTEEEEEEEETAEVGRGAEAEAGDLEQLSSSSTSTKSAKSGSEASASASKDALQAMILSL
PRYHCENPASCKSPTLSTDTLRKRLYRIGLNLFNINPDKGIQFLISRGFIPDTPIGVAHFLLQRKGLSRQMIGEFLGNSKKQFNRDVLDC
VVDEMDFSSMELDEALRKFQAHIRVQGEAQKVERLIEAFSQRYCMCNPEVVQQFHNPDTIFILAFAIILLNTDMYSPNIKPDRKMMLEDF
IRNLRGVDDGADIPRELVVGIYERIQQKELKSNEDHVTYVTKVEKSIVGMKTVLSVPHRRLVCCSRLFEVTDVNKLQKQAAHQREVFLFN
DLLVILKLCPKKKSSSTYTFCKSVGLLGMQFQLFENEYYSHGITLVTPLSGSEKKQVLHFCALGSDEMQKFVEDLKESIAEVTELEQIRI
EWELEKQQGTKTLSFKPCGAQGDPQSKQGSPTAKREAALRERPAESTVEVSIHNRLQTSQHNSGLGAERGAPVPPPDLQPSPPRQQTPPL
PPPPPTPPGTLVQCQQIVKVIVLDKPCLARMEPLLSQALSCYTSSSSDSCGSTPLGGPGSPVKVTHQPPLPPPPPPYNHPHQFCPPGSLL

--------------------------------------------------------------
>99331_99331_5_WNK1-IQSEC3_WNK1_chr12_863490_ENST00000447667_IQSEC3_chr12_247432_ENST00000326261_length(transcript)=7229nt_BP=1269nt
CCACTCCTCTGCCCCGGGGCCGCCACCGCCCGGGCGTCGGACCTGGTCCCGTGCTCGCGGTGCCGCCGCCCTCTGGGCCTAGCCCGCCCA
GCTCGGCGAGCGGCGGCAGTGGGAGCCGCGTCCGCCGCATCCGCCTCGACTCGGTGCCGGCCCCTGGCCCTCCCCTCATGACTGCGGCGC
CTCTGCTGCCACCGCCCGCCCGGCCGCCGCTCGCCGCAGGATGGATGCGGACCGTGCGGCGCTAACCCCCGTGGCTCAGCTCCCGAATCG
CCCGCCTTCGAGCCCTCCTCGTGAGCCGCAGCAGCCTCGGTGCCAGCCCCCGCCGCAGCTGGGCCCAGCGGTCCGCCTGTCCCTCGTTGC
GGCTTGTCGGTGCTGAGTGAGGCGTCGTCCGGGTCGGCGCGAACCCGCCCGGCCGCGGTTCCCTGCAGACCTCTGCGCGGGCGGCTCGGC
CCTTCACGCCCTTTTCGTTCACGAATCCGAGCCCGCTCGCCTCTCTCCAGCGAACCGACCATGTCTGGCGGCGCCGCAGAGAAGCAGAGC
AGCACTCCCGGTTCCCTGTTCCTCTCGCCGCCGGCTCCTGCCCCCAAGAATGGCTCCAGCTCCGATTCCTCCGTGGGGGAGAAACTGGGA
GCCGCGGCCGCCGACGCTGTGACCGGCAGGACCGAGGAGTACAGGCGCCGCCGCCACACTATGGACAAGGACAGCCGTGGGGCGGCCGCG
ACCACTACCACCACTGAGCACCGCTTCTTCCGCCGGAGCGTCATCTGTGACTCCAATGCCACTGCACTGGAGCTTCCCGGCCTTCCTCTT
TCCCTGCCCCAGCCCAGCATCCCCGCGGCTGTCCCGCAGAGTGCTCCACCGGAGCCCCACCGGGAAGAGACCGTGACCGCCACCGCCACT
TCCCAGGTAGCCCAGCAGCCTCCAGCCGCTGCCGCCCCTGGGGAACAGGCCGTCGCGGGCCCTGCCCCCTCGACTGTCCCCAGCAGTACC
AGCAAAGACCGCCCAGTGTCCCAGCCTAGCCTTGTGGGGAGCAAAGAGGAGCCGCCGCCGGCGAGAAGTGGCAGCGGCGGCGGCAGCGCC
AAGGAGCCACAGGAGGAACGGAGCCAGCAGCAGGATGATATCGAAGAGCTGGAGACCAAGGCCGTGGGAATGTCTAACGATGGCCGCTTT
CTCAAGTTTGACATCGAAATCGGCAGAGGCTCCTTTAAGACGGTCTACAAAGGTCTGGACACTGAAACCACCGTGGAAGTCGCCTGGTGT
GAACTGCAGATTGAAATGCTAGAACATAAGTACGGCGGTCACCTGGTGTCCCGGCGCGCCGCTTGCACCATCCAAACCGCCTTCCGCCAA
TACCAGCTCAGCAAGAACTTCGAGAAAATCCGCAACTCGCTTCTGGAGAGCCGCCTGCCACGGCGGATCTCCCTGCGCAAGGTGCGGTCA
CCCACGGCCGAGAGCCTGGCGGCCGAGAAAGCGCTCATGGAGGGCTACGGCCTCGTGGGGCTGCCGCTGGTGCGCTCGCCCTCCCTGCCG
CCCACCTTCGCAGGCACCCTCACCGAGCTGGAGGACTCCTTCACCGAGCAGGTGCAATCCCTGGCCAAGTCCATCGACGACGCGCTCAGC
ACGTGGAGCCTCAAGACCATGTGCTCCCTGCGGGAGAGTGGCGCTTACCAGCTCCACCAGGCCCTGCAGGCGGCCGCGGGGCCCCCAGGC
CTGGAGGCCGAGGGGCGGGCGCCGGAGAGCGCGGGCCCCGGGCCCGGGGATGACGCCGCGGAGACCCCCGGCCTGCCCCCGGCCCACAGC
GGGACCCTCATGATGGCTTTCCGGGACGTCACGGTGCAGATCGCCAACCAGAACATATCCGTCTCCTCCTCCACGGCTCTGTCGGTGGCC
AACTGCCTGGGCGCTCAGACGGTCCAGGCCCCCGCAGAGCCCGCGGCGGGCAAGGCCGAGCAGGGCGAGACCTCTGGGCGGGAGGCCCCG
GAAGCCCCCGCCGTGGGCCGGGAGGACGCGTCAGCCGAGGACTCATGCGCAGAGGCTGCGGCTAGTGGGGCGGCGGATGGGGCCACAGCC
CCCAAAACAGAGGAGGAAGAGGAGGAGGAGGAGACGGCGGAGGTGGGGAGAGGGGCCGAGGCCGAGGCAGGCGACTTGGAGCAGCTGAGC
AGCAGCAGCACGTCCACCAAGTCCGCCAAGTCAGGCTCGGAGGCGTCGGCCTCCGCCTCCAAGGACGCCCTGCAGGCCATGATCCTGAGC
CTGCCGCGCTACCACTGCGAGAACCCAGCCAGCTGCAAGTCGCCCACGCTCTCCACCGACACCCTGCGCAAGCGGCTCTACCGCATCGGC
CTCAACCTCTTCAACATAAACCCCGACAAGGGCATCCAGTTCCTGATCTCACGCGGCTTCATCCCGGACACCCCCATCGGTGTGGCCCAT
TTCCTCCTCCAGCGAAAGGGCCTCAGCCGCCAGATGATTGGAGAGTTCCTGGGCAACAGCAAGAAGCAGTTCAACCGCGACGTGCTGGAC
TGCGTGGTGGACGAGATGGACTTCTCCAGCATGGAGCTGGACGAGGCCCTGCGCAAGTTCCAGGCACACATCCGTGTGCAGGGGGAGGCT
CAGAAGGTGGAGCGGCTCATTGAGGCCTTCAGCCAGCGCTACTGCATGTGCAACCCCGAAGTGGTTCAGCAGTTCCACAACCCCGACACC
ATCTTCATCCTCGCCTTCGCCATCATCCTCCTCAACACCGACATGTACAGCCCCAACATCAAGCCTGACCGGAAGATGATGCTGGAGGAC
TTCATCCGAAACCTTCGAGGTGTGGACGATGGCGCTGACATCCCCAGGGAGCTGGTGGTAGGCATCTATGAGAGGATACAGCAGAAGGAG
CTCAAGTCCAATGAGGACCACGTCACGTACGTCACCAAGGTGGAGAAGTCCATTGTGGGCATGAAGACAGTGCTGTCCGTGCCCCACCGC
CGCCTGGTGTGCTGCAGCCGGCTCTTCGAGGTGACGGATGTGAACAAGCTGCAGAAGCAGGCAGCGCATCAGAGGGAGGTGTTCCTCTTC
AATGACCTGCTGGTGATTCTCAAACTTTGCCCGAAGAAGAAGAGCTCCTCCACGTACACCTTTTGCAAGTCAGTTGGCCTGCTGGGCATG
CAGTTCCAGCTCTTTGAGAACGAGTATTACTCTCATGGCATCACACTGGTGACCCCGCTCTCGGGCTCCGAGAAGAAGCAGGTGCTGCAT
TTCTGTGCCCTGGGCTCGGACGAGATGCAGAAGTTCGTGGAGGACCTGAAGGAGTCCATTGCTGAGGTGACGGAGCTGGAGCAGATCCGA
ATAGAGTGGGAGCTGGAGAAGCAGCAGGGAACAAAGACACTCTCCTTCAAGCCCTGCGGAGCCCAGGGGGACCCACAGTCAAAGCAAGGA
TCGCCGACAGCCAAAAGGGAAGCCGCGCTCAGGGAGAGGCCGGCGGAGAGCACGGTGGAGGTGTCAATTCACAACAGGCTTCAAACGTCC
CAGCACAACTCCGGGCTGGGGGCCGAGAGGGGAGCGCCGGTGCCGCCGCCAGACCTGCAGCCTAGCCCCCCGAGACAGCAGACCCCACCA
CTGCCGCCGCCGCCACCCACGCCCCCGGGCACCCTGGTGCAGTGCCAGCAAATTGTCAAGGTCATTGTCCTGGACAAGCCCTGCCTGGCC
CGCATGGAGCCCCTGCTGAGCCAGGCTCTCTCCTGCTACACCTCGTCGTCCTCTGACTCCTGCGGCTCCACACCCCTGGGCGGTCCCGGC
TCTCCGGTCAAGGTCACCCACCAGCCTCCGCTGCCCCCGCCCCCACCCCCCTACAACCACCCTCACCAGTTCTGTCCCCCAGGCTCCCTG
CTGCACGGGCACCGCTACTCCAGTGGCTCAAGGAGCCTGGTGTAGACTCTGCCCCACCACCCTGCTGTCCTGGGAGGGCTGGCCACTGGG
GGGCCTGGGCTGCCCCTCCACTGCTCCCCATACCCTGGCACGATGCGTTCCTGGTCACTGATCACCATCATTTTGGGAAGAGAATCCCAA
TCCCTGGCACCTGGGTTTGCCTCATCCAACCATCCTTCCCTTTCTCAGCTGCACCCCCTCTGCAGATCTGAAGACACACCTCACTCTCCC
AGGGCCCTACACAGCCAGACCCGGCGAGGCCTCCTCTTCCCCTGGCCACCACTTTCCCCCATTGGACCATGGACTGAAGAAAACGAGCTG
AGGGTCTAACGAGCTTGCAGGCTTTGAGTCTGTTAGTGCCCGGGGCCTCGGGCCTTGGGCAGCAGCATGAGGCTGGGCCGGCCGGCAGTG
GAGCACTAGACAGAGTGGCTGGCTCGCAGCCCAGAACTAGTGCCTCTGTAGCTGCACTGAGGGGAGGAGGGTTGGTCCCACCCCTGGAGG
GACAGGTGGGAGGAGTGAGGAGGGGGCTTTTTCTGCCACCCCCGCCCCCAAGCCTGAAACTCTCAGGAGTCTACTTCTTGGTCCCCAGGG
ACATTGGCTGTCCTGACCATGTCCTTCCCCCTCCTCCCAGGGCCTCTGCTTCCTCAGGAGCTGCCCAGACTCCAGAAAAGCCTGGAAAAA
GGGAGGCGGGAAGGGGAGCACTTTCGGCTTTCTATAGGTCAGTCCAGCAGGGCCACGGGATCGCGAGGTCATGTATCTGCAAAATGCACC
TTTTTAAAGAGTGTCTTAGTTCCCCAGCCCCAGCTAATACCCGGCCAATGCCGTGTACGCACCGGCATGTGCACGCAAACACGCATGAGA
ACCAGGCCATTCCTTCCGCTGTGGAAGCAGAACTGGAGACGGGGCAGGAATGTGCCCAGCAGAGATGGGGCTCAGCCCGAGGCAGGGCTC
CCTCCTGCATGAGGCTCGGCCCGAGGCAGGGCTCCCTCCTGCATGAGTCTGTGGCCTCCAGGAGGGACTTGGGTGCAGATGTAAGCAAGA
AAAACCGGGGCTCCAGAGGCATGTGCATTTCCCCTGCGCCCCTCAGCCTTTAAATATTCCCTCCTCCTAGAAGGTTCTAGACCCCCCCCT
TCCAGCAGGGGTGCCCAAGAGTCCCTGGACCCTCAAAATTGCAAAGGAGACCCAAGCGGGGCTCGCTGACCTCCCAGGGCCCAGCAAGAT
GGGATAGCCAGCCTTAGGTGGCCCCACGAGCCCAAGCCTGGGGAAGGGCCCCTCCCCAGCCAGACGAGAGGCAGCCACCCCAGAGACCAC
AGGAGCCGTACCATGGCCTGCGCAGTCAGGCCCTATCAGGATGTGTCTGTCCCAAGCCTGGCCAGGCTCCAGTCCTGTGCCAGTAGCTCA
CTGCTGTCCTATGTGCAGGTCCCCCAACACTTGGAGCCTGTGGTTAAGGCCTCCTGGGAGAGGCAGTGAGCATGAGTCAAAGGTGACATG
GACTTGAATCTCCCCACCCCGCCCCGCCTGCAGTAGCCGGGCCAGGTAGGAGGCAAGGATCATTCCCTGCTCCCAGAGGTTCCAGATGAC
CTAGTTTCGTTTTGTGTGTGTGTGTGTGTGGTCACCCAGACGTCACTGTGATATCACCTAGTGAATCTATTTCTGGCCCTGTCTTCGTCG
GCCCAGTTTCTGTAACTTGCAGCCAATTTGCCCTCTCCCCTGTGGCTGCCAGCCCATCTGCCCCTCTGTGTCCTTGCTGCCCTGGCCCTC
CTCTGTTTTCTGTAACAGATGCTCCAGTCATTGCCTTTCAGAGTGGAGCAGATGACAGATGGGGTGCACGCATTCAGACACCTCTGATGC
CCTTAGCCAGGGCAGGGATCGTCCTTAAAGTGAAGGCCTGGACAGGAGGAGTCAGGGACTTGGGAGGAGGTGGAGCTGTGGGGATGGGAG
TGGAGGAATCAAAATGAGGGAAGCTGAAAATAGAATGAAAACGATGACTAAGAGGCAGGGAGTGCGAGGTATGGGGGAATAGGAACTATG
AGCTAAATATACTTATGGGGTGGGGGCCGTGGGGGCCAGGGACACTCTCCCAGACAGCCCTGACCCGCCAGGCAGGACCCCGTCCCCTGC
TCACACAGCTCTTCAAACTTACCAAGGACAGGCAGGACCCCGTCCCCTGCTCACACAGCTCTTCAAGCTTACCAAGTCCCCTGTTGAGGG
CACAGCAACCCCAGGCCCTCCCTCCCACCTCAGCTGAAGCCCCAATCTTCCAAATCGGAACCAGCAAGTCTTAGGGCTGGCACGCATCTG
GGCCTCTAGCTGAGAACCCGGACTCTCAGGCACCTCAGTGCCCCTGCCCCAGGGCAGAGGCCCACCCCGTGGGTTGGTGCAGTGGCTGCC
CTGGGCTCCACGGGCAGCACAGGGAGTCTGTCCAGGAAGCAGCCCAGCCGGGGTCAGTATTCCGTGGAGCCAGTCCTGAGCTGGGAGGGG
CATTTAACACCCCTGAGGGCCTGGGGCAGGACACAGCTGGCCCTCCTCATTGTCAGGGGAAGCAAGTGCCCAACATCTGTAACCTCCCTT
CCCTGCTCAGTCCCCAGGCCAAGGTTGGGACCCCTCTCCATCCCTGTCCCCAGAGCCTAGACCTCAGGGACCTAGGAAAAGCCTCCTGCT
CCCTCCCCACGGCAGCAGACAGGGCAGGGCCTCCAGCCCCCAGAGGGCCGGTGGGGGGTGCTCTCGGGCCTTCCTGCTCTCCTAAGGTTG
CGGGGACAGTAGAGTGCTGAGCCCCAGACCCAGTCACCCCAAGATGGCCCCACTCTATCCACTCTCTAGACCTTTGGGAAATCTGGGTCC
CTCTCCTGATTTGATCCATTCGGCCCCAACTCCAGAGTCGGGAATGGGAGATGAAACTAGTTTTCCACCCACTTTTGGACAAGTCCCACC
CCTAGATCTGAAGCAAGCTCTACCAGCAGCGTGTCCTGGAAGCCTGCCTGCCTGCCTGCCCGTCTGCACAGGTGTCTTGATCCAGCCCTG
CGTCTTCGAGCCCCTGTGCCACCGGTCCCCACGGCCCGCCAGGAGTCTCTTTGTACCCACTAGGCTTCCCTGATGACCATCTGTCTGTCC
GTCCCTGTTTTTGCTGTACATAACTCCTGCTGCACCCTCTCCCCGCACACCCGTCACCCATGAGAGAGAGAAACCTCTCTAGGGAAAGGC
AGGGTGGCTGCACCCAGCAACTAATCCAAATGGCAAATATTTTGTAACAAAATAGCCCAGAGGTATTTTATCTGTTCAATTCATAGAGTT

>99331_99331_5_WNK1-IQSEC3_WNK1_chr12_863490_ENST00000447667_IQSEC3_chr12_247432_ENST00000326261_length(amino acids)=1183AA_BP=300
MSVLSEASSGSARTRPAAVPCRPLRGRLGPSRPFRSRIRARSPLSSEPTMSGGAAEKQSSTPGSLFLSPPAPAPKNGSSSDSSVGEKLGA
AAADAVTGRTEEYRRRRHTMDKDSRGAAATTTTTEHRFFRRSVICDSNATALELPGLPLSLPQPSIPAAVPQSAPPEPHREETVTATATS
QVAQQPPAAAAPGEQAVAGPAPSTVPSSTSKDRPVSQPSLVGSKEEPPPARSGSGGGSAKEPQEERSQQQDDIEELETKAVGMSNDGRFL
KFDIEIGRGSFKTVYKGLDTETTVEVAWCELQIEMLEHKYGGHLVSRRAACTIQTAFRQYQLSKNFEKIRNSLLESRLPRRISLRKVRSP
TAESLAAEKALMEGYGLVGLPLVRSPSLPPTFAGTLTELEDSFTEQVQSLAKSIDDALSTWSLKTMCSLRESGAYQLHQALQAAAGPPGL
EAEGRAPESAGPGPGDDAAETPGLPPAHSGTLMMAFRDVTVQIANQNISVSSSTALSVANCLGAQTVQAPAEPAAGKAEQGETSGREAPE
APAVGREDASAEDSCAEAAASGAADGATAPKTEEEEEEEETAEVGRGAEAEAGDLEQLSSSSTSTKSAKSGSEASASASKDALQAMILSL
PRYHCENPASCKSPTLSTDTLRKRLYRIGLNLFNINPDKGIQFLISRGFIPDTPIGVAHFLLQRKGLSRQMIGEFLGNSKKQFNRDVLDC
VVDEMDFSSMELDEALRKFQAHIRVQGEAQKVERLIEAFSQRYCMCNPEVVQQFHNPDTIFILAFAIILLNTDMYSPNIKPDRKMMLEDF
IRNLRGVDDGADIPRELVVGIYERIQQKELKSNEDHVTYVTKVEKSIVGMKTVLSVPHRRLVCCSRLFEVTDVNKLQKQAAHQREVFLFN
DLLVILKLCPKKKSSSTYTFCKSVGLLGMQFQLFENEYYSHGITLVTPLSGSEKKQVLHFCALGSDEMQKFVEDLKESIAEVTELEQIRI
EWELEKQQGTKTLSFKPCGAQGDPQSKQGSPTAKREAALRERPAESTVEVSIHNRLQTSQHNSGLGAERGAPVPPPDLQPSPPRQQTPPL
PPPPPTPPGTLVQCQQIVKVIVLDKPCLARMEPLLSQALSCYTSSSSDSCGSTPLGGPGSPVKVTHQPPLPPPPPPYNHPHQFCPPGSLL

--------------------------------------------------------------
>99331_99331_6_WNK1-IQSEC3_WNK1_chr12_863490_ENST00000447667_IQSEC3_chr12_247432_ENST00000538872_length(transcript)=7342nt_BP=1269nt
CCACTCCTCTGCCCCGGGGCCGCCACCGCCCGGGCGTCGGACCTGGTCCCGTGCTCGCGGTGCCGCCGCCCTCTGGGCCTAGCCCGCCCA
GCTCGGCGAGCGGCGGCAGTGGGAGCCGCGTCCGCCGCATCCGCCTCGACTCGGTGCCGGCCCCTGGCCCTCCCCTCATGACTGCGGCGC
CTCTGCTGCCACCGCCCGCCCGGCCGCCGCTCGCCGCAGGATGGATGCGGACCGTGCGGCGCTAACCCCCGTGGCTCAGCTCCCGAATCG
CCCGCCTTCGAGCCCTCCTCGTGAGCCGCAGCAGCCTCGGTGCCAGCCCCCGCCGCAGCTGGGCCCAGCGGTCCGCCTGTCCCTCGTTGC
GGCTTGTCGGTGCTGAGTGAGGCGTCGTCCGGGTCGGCGCGAACCCGCCCGGCCGCGGTTCCCTGCAGACCTCTGCGCGGGCGGCTCGGC
CCTTCACGCCCTTTTCGTTCACGAATCCGAGCCCGCTCGCCTCTCTCCAGCGAACCGACCATGTCTGGCGGCGCCGCAGAGAAGCAGAGC
AGCACTCCCGGTTCCCTGTTCCTCTCGCCGCCGGCTCCTGCCCCCAAGAATGGCTCCAGCTCCGATTCCTCCGTGGGGGAGAAACTGGGA
GCCGCGGCCGCCGACGCTGTGACCGGCAGGACCGAGGAGTACAGGCGCCGCCGCCACACTATGGACAAGGACAGCCGTGGGGCGGCCGCG
ACCACTACCACCACTGAGCACCGCTTCTTCCGCCGGAGCGTCATCTGTGACTCCAATGCCACTGCACTGGAGCTTCCCGGCCTTCCTCTT
TCCCTGCCCCAGCCCAGCATCCCCGCGGCTGTCCCGCAGAGTGCTCCACCGGAGCCCCACCGGGAAGAGACCGTGACCGCCACCGCCACT
TCCCAGGTAGCCCAGCAGCCTCCAGCCGCTGCCGCCCCTGGGGAACAGGCCGTCGCGGGCCCTGCCCCCTCGACTGTCCCCAGCAGTACC
AGCAAAGACCGCCCAGTGTCCCAGCCTAGCCTTGTGGGGAGCAAAGAGGAGCCGCCGCCGGCGAGAAGTGGCAGCGGCGGCGGCAGCGCC
AAGGAGCCACAGGAGGAACGGAGCCAGCAGCAGGATGATATCGAAGAGCTGGAGACCAAGGCCGTGGGAATGTCTAACGATGGCCGCTTT
CTCAAGTTTGACATCGAAATCGGCAGAGGCTCCTTTAAGACGGTCTACAAAGGTCTGGACACTGAAACCACCGTGGAAGTCGCCTGGTGT
GAACTGCAGATTGAAATGCTAGAACATAAGTACGGCGGTCACCTGGTGTCCCGGCGCGCCGCTTGCACCATCCAAACCGCCTTCCGCCAA
TACCAGCTCAGCAAGAACTTCGAGAAAATCCGCAACTCGCTTCTGGAGAGCCGCCTGCCACGGCGGATCTCCCTGCGCAAGGTGCGGTCA
CCCACGGCCGAGAGCCTGGCGGCCGAGAAAGCGCTCATGGAGGGCTACGGCCTCGTGGGGCTGCCGCTGGTGCGCTCGCCCTCCCTGCCG
CCCACCTTCGCAGGCACCCTCACCGAGCTGGAGGACTCCTTCACCGAGCAGGTGCAATCCCTGGCCAAGTCCATCGACGACGCGCTCAGC
ACGTGGAGCCTCAAGACCATGTGCTCCCTGCGGGAGAGTGGCGCTTACCAGCTCCACCAGGCCCTGCAGGCGGCCGCGGGGCCCCCAGGC
CTGGAGGCCGAGGGGCGGGCGCCGGAGAGCGCGGGCCCCGGGCCCGGGGATGACGCCGCGGAGACCCCCGGCCTGCCCCCGGCCCACAGC
GGGACCCTCATGATGGCTTTCCGGGACGTCACGGTGCAGATCGCCAACCAGAACATATCCGTCTCCTCCTCCACGGCTCTGTCGGTGGCC
AACTGCCTGGGCGCTCAGACGGTCCAGGCCCCCGCAGAGCCCGCGGCGGGCAAGGCCGAGCAGGGCGAGACCTCTGGGCGGGAGGCCCCG
GAAGCCCCCGCCGTGGGCCGGGAGGACGCGTCAGCCGAGGACTCATGCGCAGAGGCTGCGGCTAGTGGGGCGGCGGATGGGGCCACAGCC
CCCAAAACAGAGGAGGAAGAGGAGGAGGAGGAGACGGCGGAGGTGGGGAGAGGGGCCGAGGCCGAGGCAGGCGACTTGGAGCAGCTGAGC
AGCAGCAGCACGTCCACCAAGTCCGCCAAGTCAGGCTCGGAGGCGTCGGCCTCCGCCTCCAAGGACGCCCTGCAGGCCATGATCCTGAGC
CTGCCGCGCTACCACTGCGAGAACCCAGCCAGCTGCAAGTCGCCCACGCTCTCCACCGACACCCTGCGCAAGCGGCTCTACCGCATCGGC
CTCAACCTCTTCAACATAAACCCCGACAAGGGCATCCAGTTCCTGATCTCACGCGGCTTCATCCCGGACACCCCCATCGGTGTGGCCCAT
TTCCTCCTCCAGCGAAAGGGCCTCAGCCGCCAGATGATTGGAGAGTTCCTGGGCAACAGCAAGAAGCAGTTCAACCGCGACGTGCTGGAC
TGCGTGGTGGACGAGATGGACTTCTCCAGCATGGAGCTGGACGAGGCCCTGCGCAAGTTCCAGGCACACATCCGTGTGCAGGGGGAGGCT
CAGAAGGTGGAGCGGCTCATTGAGGCCTTCAGCCAGCGCTACTGCATGTGCAACCCCGAAGTGGTTCAGCAGTTCCACAACCCCGACACC
ATCTTCATCCTCGCCTTCGCCATCATCCTCCTCAACACCGACATGTACAGCCCCAACATCAAGCCTGACCGGAAGATGATGCTGGAGGAC
TTCATCCGAAACCTTCGAGGTGTGGACGATGGCGCTGACATCCCCAGGGAGCTGGTGGTAGGCATCTATGAGAGGATACAGCAGAAGGAG
CTCAAGTCCAATGAGGACCACGTCACGTACGTCACCAAGGTGGAGAAGTCCATTGTGGGCATGAAGACAGTGCTGTCCGTGCCCCACCGC
CGCCTGGTGTGCTGCAGCCGGCTCTTCGAGGTGACGGATGTGAACAAGCTGCAGAAGCAGGCAGCGCATCAGAGGGAGGTGTTCCTCTTC
AATGACCTGCTGGTGATTCTCAAACTTTGCCCGAAGAAGAAGAGCTCCTCCACGTACACCTTTTGCAAGTCAGTTGGCCTGCTGGGCATG
CAGTTCCAGCTCTTTGAGAACGAGTATTACTCTCATGGCATCACACTGGTGACCCCGCTCTCGGGCTCCGAGAAGAAGCAGGTGCTGCAT
TTCTGTGCCCTGGGCTCGGACGAGATGCAGAAGTTCGTGGAGGACCTGAAGGAGTCCATTGCTGAGGTGACGGAGCTGGAGCAGATCCGA
ATAGAGTGGGAGCTGGAGAAGCAGCAGGGAACAAAGACACTCTCCTTCAAGCCCTGCGGAGCCCAGGGGGACCCACAGTCAAAGCAAGGA
TCGCCGACAGCCAAAAGGGAAGCCGCGCTCAGGGAGAGGCCGGCGGAGAGCACGGTGGAGGTGTCAATTCACAACAGGCTTCAAACGTCC
CAGCACAACTCCGGGCTGGGGGCCGAGAGGGGAGCGCCGGTGCCGCCGCCAGACCTGCAGCCTAGCCCCCCGAGACAGCAGACCCCACCA
CTGCCGCCGCCGCCACCCACGCCCCCGGGCACCCTGGTGCAGTGCCAGCAAATTGTCAAGGTCATTGTCCTGGACAAGCCCTGCCTGGCC
CGCATGGAGCCCCTGCTGAGCCAGGCTCTCTCCTGCTACACCTCGTCGTCCTCTGACTCCTGCGGCTCCACACCCCTGGGCGGTCCCGGC
TCTCCGGTCAAGGTCACCCACCAGCCTCCGCTGCCCCCGCCCCCACCCCCCTACAACCACCCTCACCAGTTCTGTCCCCCAGGCTCCCTG
CTGCACGGGCACCGCTACTCCAGTGGCTCAAGGAGCCTGGTGTAGACTCTGCCCCACCACCCTGCTGTCCTGGGAGGGCTGGCCACTGGG
GGGCCTGGGCTGCCCCTCCACTGCTCCCCATACCCTGGCACGATGCGTTCCTGGTCACTGATCACCATCATTTTGGGAAGAGAATCCCAA
TCCCTGGCACCTGGGTTTGCCTCATCCAACCATCCTTCCCTTTCTCAGCTGCACCCCCTCTGCAGATCTGAAGACACACCTCACTCTCCC
AGGGCCCTACACAGCCAGACCCGGCGAGGCCTCCTCTTCCCCTGGCCACCACTTTCCCCCATTGGACCATGGACTGAAGAAAACGAGCTG
AGGGTCTAACGAGCTTGCAGGCTTTGAGTCTGTTAGTGCCCGGGGCCTCGGGCCTTGGGCAGCAGCATGAGGCTGGGCCGGCCGGCAGTG
GAGCACTAGACAGAGTGGCTGGCTCGCAGCCCAGAACTAGTGCCTCTGTAGCTGCACTGAGGGGAGGAGGGTTGGTCCCACCCCTGGAGG
GACAGGTGGGAGGAGTGAGGAGGGGGCTTTTTCTGCCACCCCCGCCCCCAAGCCTGAAACTCTCAGGAGTCTACTTCTTGGTCCCCAGGG
ACATTGGCTGTCCTGACCATGTCCTTCCCCCTCCTCCCAGGGCCTCTGCTTCCTCAGGAGCTGCCCAGACTCCAGAAAAGCCTGGAAAAA
GGGAGGCGGGAAGGGGAGCACTTTCGGCTTTCTATAGGTCAGTCCAGCAGGGCCACGGGATCGCGAGGTCATGTATCTGCAAAATGCACC
TTTTTAAAGAGTGTCTTAGTTCCCCAGCCCCAGCTAATACCCGGCCAATGCCGTGTACGCACCGGCATGTGCACGCAAACACGCATGAGA
ACCAGGCCATTCCTTCCGCTGTGGAAGCAGAACTGGAGACGGGGCAGGAATGTGCCCAGCAGAGATGGGGCTCAGCCCGAGGCAGGGCTC
CCTCCTGCATGAGGCTCGGCCCGAGGCAGGGCTCCCTCCTGCATGAGTCTGTGGCCTCCAGGAGGGACTTGGGTGCAGATGTAAGCAAGA
AAAACCGGGGCTCCAGAGGCATGTGCATTTCCCCTGCGCCCCTCAGCCTTTAAATATTCCCTCCTCCTAGAAGGTTCTAGACCCCCCCCT
TCCAGCAGGGGTGCCCAAGAGTCCCTGGACCCTCAAAATTGCAAAGGAGACCCAAGCGGGGCTCGCTGACCTCCCAGGGCCCAGCAAGAT
GGGATAGCCAGCCTTAGGTGGCCCCACGAGCCCAAGCCTGGGGAAGGGCCCCTCCCCAGCCAGACGAGAGGCAGCCACCCCAGAGACCAC
AGGAGCCGTACCATGGCCTGCGCAGTCAGGCCCTATCAGGATGTGTCTGTCCCAAGCCTGGCCAGGCTCCAGTCCTGTGCCAGTAGCTCA
CTGCTGTCCTATGTGCAGGTCCCCCAACACTTGGAGCCTGTGGTTAAGGCCTCCTGGGAGAGGCAGTGAGCATGAGTCAAAGGTGACATG
GACTTGAATCTCCCCACCCCGCCCCGCCTGCAGTAGCCGGGCCAGGTAGGAGGCAAGGATCATTCCCTGCTCCCAGAGGTTCCAGATGAC
CTAGTTTCGTTTTGTGTGTGTGTGTGTGTGGTCACCCAGACGTCACTGTGATATCACCTAGTGAATCTATTTCTGGCCCTGTCTTCGTCG
GCCCAGTTTCTGTAACTTGCAGCCAATTTGCCCTCTCCCCTGTGGCTGCCAGCCCATCTGCCCCTCTGTGTCCTTGCTGCCCTGGCCCTC
CTCTGTTTTCTGTAACAGATGCTCCAGTCATTGCCTTTCAGAGTGGAGCAGATGACAGATGGGGTGCACGCATTCAGACACCTCTGATGC
CCTTAGCCAGGGCAGGGATCGTCCTTAAAGTGAAGGCCTGGACAGGAGGAGTCAGGGACTTGGGAGGAGGTGGAGCTGTGGGGATGGGAG
TGGAGGAATCAAAATGAGGGAAGCTGAAAATAGAATGAAAACGATGACTAAGAGGCAGGGAGTGCGAGGTATGGGGGAATAGGAACTATG
AGCTAAATATACTTATGGGGTGGGGGCCGTGGGGGCCAGGGACACTCTCCCAGACAGCCCTGACCCGCCAGGCAGGACCCCGTCCCCTGC
TCACACAGCTCTTCAAACTTACCAAGGACAGGCAGGACCCCGTCCCCTGCTCACACAGCTCTTCAAGCTTACCAAGGACAGGCAGAACCC
CGTCCCCTGCTCACACAGCTCTTCAAGCTTACCAAGGACAGGCAGGACCCCGTCCCCTGCTCACACAGCTCTTCAAACTTACCAAGTGCC
CTCTCCCCTGTTGAGGGCACAGCAACCCCAGGCCCTCCCTCCCACCTCAGCTGAAGCCCCAATCTTCCAAATCGGAACCAGCAAGTCTTA
GGGCTGGCACGCATCTGGGCCTCTAGCTGAGAACCCGGACTCTCAGGCACCTCAGTGCCCCTGCCCCAGGGCAGAGGCCCACCCCGTGGG
TTGGTGCAGTGGCTGCCCTGGGCTCCACGGGCAGCACAGGGAGTCTGTCCAGGAAGCAGCCCAGCCGGGGTCAGTATTCCGTGGAGCCAG
TCCTGAGCTGGGAGGGGCATTTAACACCCCTGAGGGCCTGGGGCAGGACACAGCTGGCCCTCCTCATTGTCAGGGGAAGCAAGTGCCCAA
CATCTGTAACCTCCCTTCCCTGCTCAGTCCCCAGGCCAAGGTTGGGACCCCTCTCCATCCCTGTCCCCAGAGCCTAGACCTCAGGGACCT
AGGAAAAGCCTCCTGCTCCCTCCCCACGGCAGCAGACAGGGCAGGGCCTCCAGCCCCCAGAGGGCCGGTGGGGGGTGCTCTCGGGCCTTC
CTGCTCTCCTAAGGTTGCGGGGACAGTAGAGTGCTGAGCCCCAGACCCAGTCACCCCAAGATGGCCCCACTCTATCCACTCTCTAGACCT
TTGGGAAATCTGGGTCCCTCTCCTGATTTGATCCATTCGGCCCCAACTCCAGAGTCGGGAATGGGAGATGAAACTAGTTTTCCACCCACT
TTTGGACAAGTCCCACCCCTAGATCTGAAGCAAGCTCTACCAGCAGCGTGTCCTGGAAGCCTGCCTGCCTGCCTGCCCGTCTGCACAGGT
GTCTTGATCCAGCCCTGCGTCTTCGAGCCCCTGTGCCACCGGTCCCCACGGCCCGCCAGGAGTCTCTTTGTACCCACTAGGCTTCCCTGA
TGACCATCTGTCTGTCCGTCCCTGTTTTTGCTGTACATAACTCCTGCTGCACCCTCTCCCCGCACACCCGTCACCCATGAGAGAGAGAAA
CCTCTCTAGGGAAAGGCAGGGTGGCTGCACCCAGCAACTAATCCAAATGGCAAATATTTTGTAACAAAATAGCCCAGAGGTATTTTATCT

>99331_99331_6_WNK1-IQSEC3_WNK1_chr12_863490_ENST00000447667_IQSEC3_chr12_247432_ENST00000538872_length(amino acids)=1183AA_BP=300
MSVLSEASSGSARTRPAAVPCRPLRGRLGPSRPFRSRIRARSPLSSEPTMSGGAAEKQSSTPGSLFLSPPAPAPKNGSSSDSSVGEKLGA
AAADAVTGRTEEYRRRRHTMDKDSRGAAATTTTTEHRFFRRSVICDSNATALELPGLPLSLPQPSIPAAVPQSAPPEPHREETVTATATS
QVAQQPPAAAAPGEQAVAGPAPSTVPSSTSKDRPVSQPSLVGSKEEPPPARSGSGGGSAKEPQEERSQQQDDIEELETKAVGMSNDGRFL
KFDIEIGRGSFKTVYKGLDTETTVEVAWCELQIEMLEHKYGGHLVSRRAACTIQTAFRQYQLSKNFEKIRNSLLESRLPRRISLRKVRSP
TAESLAAEKALMEGYGLVGLPLVRSPSLPPTFAGTLTELEDSFTEQVQSLAKSIDDALSTWSLKTMCSLRESGAYQLHQALQAAAGPPGL
EAEGRAPESAGPGPGDDAAETPGLPPAHSGTLMMAFRDVTVQIANQNISVSSSTALSVANCLGAQTVQAPAEPAAGKAEQGETSGREAPE
APAVGREDASAEDSCAEAAASGAADGATAPKTEEEEEEEETAEVGRGAEAEAGDLEQLSSSSTSTKSAKSGSEASASASKDALQAMILSL
PRYHCENPASCKSPTLSTDTLRKRLYRIGLNLFNINPDKGIQFLISRGFIPDTPIGVAHFLLQRKGLSRQMIGEFLGNSKKQFNRDVLDC
VVDEMDFSSMELDEALRKFQAHIRVQGEAQKVERLIEAFSQRYCMCNPEVVQQFHNPDTIFILAFAIILLNTDMYSPNIKPDRKMMLEDF
IRNLRGVDDGADIPRELVVGIYERIQQKELKSNEDHVTYVTKVEKSIVGMKTVLSVPHRRLVCCSRLFEVTDVNKLQKQAAHQREVFLFN
DLLVILKLCPKKKSSSTYTFCKSVGLLGMQFQLFENEYYSHGITLVTPLSGSEKKQVLHFCALGSDEMQKFVEDLKESIAEVTELEQIRI
EWELEKQQGTKTLSFKPCGAQGDPQSKQGSPTAKREAALRERPAESTVEVSIHNRLQTSQHNSGLGAERGAPVPPPDLQPSPPRQQTPPL
PPPPPTPPGTLVQCQQIVKVIVLDKPCLARMEPLLSQALSCYTSSSSDSCGSTPLGGPGSPVKVTHQPPLPPPPPPYNHPHQFCPPGSLL

--------------------------------------------------------------
>99331_99331_7_WNK1-IQSEC3_WNK1_chr12_863490_ENST00000447667_IQSEC3_chr12_247433_ENST00000326261_length(transcript)=7229nt_BP=1269nt
CCACTCCTCTGCCCCGGGGCCGCCACCGCCCGGGCGTCGGACCTGGTCCCGTGCTCGCGGTGCCGCCGCCCTCTGGGCCTAGCCCGCCCA
GCTCGGCGAGCGGCGGCAGTGGGAGCCGCGTCCGCCGCATCCGCCTCGACTCGGTGCCGGCCCCTGGCCCTCCCCTCATGACTGCGGCGC
CTCTGCTGCCACCGCCCGCCCGGCCGCCGCTCGCCGCAGGATGGATGCGGACCGTGCGGCGCTAACCCCCGTGGCTCAGCTCCCGAATCG
CCCGCCTTCGAGCCCTCCTCGTGAGCCGCAGCAGCCTCGGTGCCAGCCCCCGCCGCAGCTGGGCCCAGCGGTCCGCCTGTCCCTCGTTGC
GGCTTGTCGGTGCTGAGTGAGGCGTCGTCCGGGTCGGCGCGAACCCGCCCGGCCGCGGTTCCCTGCAGACCTCTGCGCGGGCGGCTCGGC
CCTTCACGCCCTTTTCGTTCACGAATCCGAGCCCGCTCGCCTCTCTCCAGCGAACCGACCATGTCTGGCGGCGCCGCAGAGAAGCAGAGC
AGCACTCCCGGTTCCCTGTTCCTCTCGCCGCCGGCTCCTGCCCCCAAGAATGGCTCCAGCTCCGATTCCTCCGTGGGGGAGAAACTGGGA
GCCGCGGCCGCCGACGCTGTGACCGGCAGGACCGAGGAGTACAGGCGCCGCCGCCACACTATGGACAAGGACAGCCGTGGGGCGGCCGCG
ACCACTACCACCACTGAGCACCGCTTCTTCCGCCGGAGCGTCATCTGTGACTCCAATGCCACTGCACTGGAGCTTCCCGGCCTTCCTCTT
TCCCTGCCCCAGCCCAGCATCCCCGCGGCTGTCCCGCAGAGTGCTCCACCGGAGCCCCACCGGGAAGAGACCGTGACCGCCACCGCCACT
TCCCAGGTAGCCCAGCAGCCTCCAGCCGCTGCCGCCCCTGGGGAACAGGCCGTCGCGGGCCCTGCCCCCTCGACTGTCCCCAGCAGTACC
AGCAAAGACCGCCCAGTGTCCCAGCCTAGCCTTGTGGGGAGCAAAGAGGAGCCGCCGCCGGCGAGAAGTGGCAGCGGCGGCGGCAGCGCC
AAGGAGCCACAGGAGGAACGGAGCCAGCAGCAGGATGATATCGAAGAGCTGGAGACCAAGGCCGTGGGAATGTCTAACGATGGCCGCTTT
CTCAAGTTTGACATCGAAATCGGCAGAGGCTCCTTTAAGACGGTCTACAAAGGTCTGGACACTGAAACCACCGTGGAAGTCGCCTGGTGT
GAACTGCAGATTGAAATGCTAGAACATAAGTACGGCGGTCACCTGGTGTCCCGGCGCGCCGCTTGCACCATCCAAACCGCCTTCCGCCAA
TACCAGCTCAGCAAGAACTTCGAGAAAATCCGCAACTCGCTTCTGGAGAGCCGCCTGCCACGGCGGATCTCCCTGCGCAAGGTGCGGTCA
CCCACGGCCGAGAGCCTGGCGGCCGAGAAAGCGCTCATGGAGGGCTACGGCCTCGTGGGGCTGCCGCTGGTGCGCTCGCCCTCCCTGCCG
CCCACCTTCGCAGGCACCCTCACCGAGCTGGAGGACTCCTTCACCGAGCAGGTGCAATCCCTGGCCAAGTCCATCGACGACGCGCTCAGC
ACGTGGAGCCTCAAGACCATGTGCTCCCTGCGGGAGAGTGGCGCTTACCAGCTCCACCAGGCCCTGCAGGCGGCCGCGGGGCCCCCAGGC
CTGGAGGCCGAGGGGCGGGCGCCGGAGAGCGCGGGCCCCGGGCCCGGGGATGACGCCGCGGAGACCCCCGGCCTGCCCCCGGCCCACAGC
GGGACCCTCATGATGGCTTTCCGGGACGTCACGGTGCAGATCGCCAACCAGAACATATCCGTCTCCTCCTCCACGGCTCTGTCGGTGGCC
AACTGCCTGGGCGCTCAGACGGTCCAGGCCCCCGCAGAGCCCGCGGCGGGCAAGGCCGAGCAGGGCGAGACCTCTGGGCGGGAGGCCCCG
GAAGCCCCCGCCGTGGGCCGGGAGGACGCGTCAGCCGAGGACTCATGCGCAGAGGCTGCGGCTAGTGGGGCGGCGGATGGGGCCACAGCC
CCCAAAACAGAGGAGGAAGAGGAGGAGGAGGAGACGGCGGAGGTGGGGAGAGGGGCCGAGGCCGAGGCAGGCGACTTGGAGCAGCTGAGC
AGCAGCAGCACGTCCACCAAGTCCGCCAAGTCAGGCTCGGAGGCGTCGGCCTCCGCCTCCAAGGACGCCCTGCAGGCCATGATCCTGAGC
CTGCCGCGCTACCACTGCGAGAACCCAGCCAGCTGCAAGTCGCCCACGCTCTCCACCGACACCCTGCGCAAGCGGCTCTACCGCATCGGC
CTCAACCTCTTCAACATAAACCCCGACAAGGGCATCCAGTTCCTGATCTCACGCGGCTTCATCCCGGACACCCCCATCGGTGTGGCCCAT
TTCCTCCTCCAGCGAAAGGGCCTCAGCCGCCAGATGATTGGAGAGTTCCTGGGCAACAGCAAGAAGCAGTTCAACCGCGACGTGCTGGAC
TGCGTGGTGGACGAGATGGACTTCTCCAGCATGGAGCTGGACGAGGCCCTGCGCAAGTTCCAGGCACACATCCGTGTGCAGGGGGAGGCT
CAGAAGGTGGAGCGGCTCATTGAGGCCTTCAGCCAGCGCTACTGCATGTGCAACCCCGAAGTGGTTCAGCAGTTCCACAACCCCGACACC
ATCTTCATCCTCGCCTTCGCCATCATCCTCCTCAACACCGACATGTACAGCCCCAACATCAAGCCTGACCGGAAGATGATGCTGGAGGAC
TTCATCCGAAACCTTCGAGGTGTGGACGATGGCGCTGACATCCCCAGGGAGCTGGTGGTAGGCATCTATGAGAGGATACAGCAGAAGGAG
CTCAAGTCCAATGAGGACCACGTCACGTACGTCACCAAGGTGGAGAAGTCCATTGTGGGCATGAAGACAGTGCTGTCCGTGCCCCACCGC
CGCCTGGTGTGCTGCAGCCGGCTCTTCGAGGTGACGGATGTGAACAAGCTGCAGAAGCAGGCAGCGCATCAGAGGGAGGTGTTCCTCTTC
AATGACCTGCTGGTGATTCTCAAACTTTGCCCGAAGAAGAAGAGCTCCTCCACGTACACCTTTTGCAAGTCAGTTGGCCTGCTGGGCATG
CAGTTCCAGCTCTTTGAGAACGAGTATTACTCTCATGGCATCACACTGGTGACCCCGCTCTCGGGCTCCGAGAAGAAGCAGGTGCTGCAT
TTCTGTGCCCTGGGCTCGGACGAGATGCAGAAGTTCGTGGAGGACCTGAAGGAGTCCATTGCTGAGGTGACGGAGCTGGAGCAGATCCGA
ATAGAGTGGGAGCTGGAGAAGCAGCAGGGAACAAAGACACTCTCCTTCAAGCCCTGCGGAGCCCAGGGGGACCCACAGTCAAAGCAAGGA
TCGCCGACAGCCAAAAGGGAAGCCGCGCTCAGGGAGAGGCCGGCGGAGAGCACGGTGGAGGTGTCAATTCACAACAGGCTTCAAACGTCC
CAGCACAACTCCGGGCTGGGGGCCGAGAGGGGAGCGCCGGTGCCGCCGCCAGACCTGCAGCCTAGCCCCCCGAGACAGCAGACCCCACCA
CTGCCGCCGCCGCCACCCACGCCCCCGGGCACCCTGGTGCAGTGCCAGCAAATTGTCAAGGTCATTGTCCTGGACAAGCCCTGCCTGGCC
CGCATGGAGCCCCTGCTGAGCCAGGCTCTCTCCTGCTACACCTCGTCGTCCTCTGACTCCTGCGGCTCCACACCCCTGGGCGGTCCCGGC
TCTCCGGTCAAGGTCACCCACCAGCCTCCGCTGCCCCCGCCCCCACCCCCCTACAACCACCCTCACCAGTTCTGTCCCCCAGGCTCCCTG
CTGCACGGGCACCGCTACTCCAGTGGCTCAAGGAGCCTGGTGTAGACTCTGCCCCACCACCCTGCTGTCCTGGGAGGGCTGGCCACTGGG
GGGCCTGGGCTGCCCCTCCACTGCTCCCCATACCCTGGCACGATGCGTTCCTGGTCACTGATCACCATCATTTTGGGAAGAGAATCCCAA
TCCCTGGCACCTGGGTTTGCCTCATCCAACCATCCTTCCCTTTCTCAGCTGCACCCCCTCTGCAGATCTGAAGACACACCTCACTCTCCC
AGGGCCCTACACAGCCAGACCCGGCGAGGCCTCCTCTTCCCCTGGCCACCACTTTCCCCCATTGGACCATGGACTGAAGAAAACGAGCTG
AGGGTCTAACGAGCTTGCAGGCTTTGAGTCTGTTAGTGCCCGGGGCCTCGGGCCTTGGGCAGCAGCATGAGGCTGGGCCGGCCGGCAGTG
GAGCACTAGACAGAGTGGCTGGCTCGCAGCCCAGAACTAGTGCCTCTGTAGCTGCACTGAGGGGAGGAGGGTTGGTCCCACCCCTGGAGG
GACAGGTGGGAGGAGTGAGGAGGGGGCTTTTTCTGCCACCCCCGCCCCCAAGCCTGAAACTCTCAGGAGTCTACTTCTTGGTCCCCAGGG
ACATTGGCTGTCCTGACCATGTCCTTCCCCCTCCTCCCAGGGCCTCTGCTTCCTCAGGAGCTGCCCAGACTCCAGAAAAGCCTGGAAAAA
GGGAGGCGGGAAGGGGAGCACTTTCGGCTTTCTATAGGTCAGTCCAGCAGGGCCACGGGATCGCGAGGTCATGTATCTGCAAAATGCACC
TTTTTAAAGAGTGTCTTAGTTCCCCAGCCCCAGCTAATACCCGGCCAATGCCGTGTACGCACCGGCATGTGCACGCAAACACGCATGAGA
ACCAGGCCATTCCTTCCGCTGTGGAAGCAGAACTGGAGACGGGGCAGGAATGTGCCCAGCAGAGATGGGGCTCAGCCCGAGGCAGGGCTC
CCTCCTGCATGAGGCTCGGCCCGAGGCAGGGCTCCCTCCTGCATGAGTCTGTGGCCTCCAGGAGGGACTTGGGTGCAGATGTAAGCAAGA
AAAACCGGGGCTCCAGAGGCATGTGCATTTCCCCTGCGCCCCTCAGCCTTTAAATATTCCCTCCTCCTAGAAGGTTCTAGACCCCCCCCT
TCCAGCAGGGGTGCCCAAGAGTCCCTGGACCCTCAAAATTGCAAAGGAGACCCAAGCGGGGCTCGCTGACCTCCCAGGGCCCAGCAAGAT
GGGATAGCCAGCCTTAGGTGGCCCCACGAGCCCAAGCCTGGGGAAGGGCCCCTCCCCAGCCAGACGAGAGGCAGCCACCCCAGAGACCAC
AGGAGCCGTACCATGGCCTGCGCAGTCAGGCCCTATCAGGATGTGTCTGTCCCAAGCCTGGCCAGGCTCCAGTCCTGTGCCAGTAGCTCA
CTGCTGTCCTATGTGCAGGTCCCCCAACACTTGGAGCCTGTGGTTAAGGCCTCCTGGGAGAGGCAGTGAGCATGAGTCAAAGGTGACATG
GACTTGAATCTCCCCACCCCGCCCCGCCTGCAGTAGCCGGGCCAGGTAGGAGGCAAGGATCATTCCCTGCTCCCAGAGGTTCCAGATGAC
CTAGTTTCGTTTTGTGTGTGTGTGTGTGTGGTCACCCAGACGTCACTGTGATATCACCTAGTGAATCTATTTCTGGCCCTGTCTTCGTCG
GCCCAGTTTCTGTAACTTGCAGCCAATTTGCCCTCTCCCCTGTGGCTGCCAGCCCATCTGCCCCTCTGTGTCCTTGCTGCCCTGGCCCTC
CTCTGTTTTCTGTAACAGATGCTCCAGTCATTGCCTTTCAGAGTGGAGCAGATGACAGATGGGGTGCACGCATTCAGACACCTCTGATGC
CCTTAGCCAGGGCAGGGATCGTCCTTAAAGTGAAGGCCTGGACAGGAGGAGTCAGGGACTTGGGAGGAGGTGGAGCTGTGGGGATGGGAG
TGGAGGAATCAAAATGAGGGAAGCTGAAAATAGAATGAAAACGATGACTAAGAGGCAGGGAGTGCGAGGTATGGGGGAATAGGAACTATG
AGCTAAATATACTTATGGGGTGGGGGCCGTGGGGGCCAGGGACACTCTCCCAGACAGCCCTGACCCGCCAGGCAGGACCCCGTCCCCTGC
TCACACAGCTCTTCAAACTTACCAAGGACAGGCAGGACCCCGTCCCCTGCTCACACAGCTCTTCAAGCTTACCAAGTCCCCTGTTGAGGG
CACAGCAACCCCAGGCCCTCCCTCCCACCTCAGCTGAAGCCCCAATCTTCCAAATCGGAACCAGCAAGTCTTAGGGCTGGCACGCATCTG
GGCCTCTAGCTGAGAACCCGGACTCTCAGGCACCTCAGTGCCCCTGCCCCAGGGCAGAGGCCCACCCCGTGGGTTGGTGCAGTGGCTGCC
CTGGGCTCCACGGGCAGCACAGGGAGTCTGTCCAGGAAGCAGCCCAGCCGGGGTCAGTATTCCGTGGAGCCAGTCCTGAGCTGGGAGGGG
CATTTAACACCCCTGAGGGCCTGGGGCAGGACACAGCTGGCCCTCCTCATTGTCAGGGGAAGCAAGTGCCCAACATCTGTAACCTCCCTT
CCCTGCTCAGTCCCCAGGCCAAGGTTGGGACCCCTCTCCATCCCTGTCCCCAGAGCCTAGACCTCAGGGACCTAGGAAAAGCCTCCTGCT
CCCTCCCCACGGCAGCAGACAGGGCAGGGCCTCCAGCCCCCAGAGGGCCGGTGGGGGGTGCTCTCGGGCCTTCCTGCTCTCCTAAGGTTG
CGGGGACAGTAGAGTGCTGAGCCCCAGACCCAGTCACCCCAAGATGGCCCCACTCTATCCACTCTCTAGACCTTTGGGAAATCTGGGTCC
CTCTCCTGATTTGATCCATTCGGCCCCAACTCCAGAGTCGGGAATGGGAGATGAAACTAGTTTTCCACCCACTTTTGGACAAGTCCCACC
CCTAGATCTGAAGCAAGCTCTACCAGCAGCGTGTCCTGGAAGCCTGCCTGCCTGCCTGCCCGTCTGCACAGGTGTCTTGATCCAGCCCTG
CGTCTTCGAGCCCCTGTGCCACCGGTCCCCACGGCCCGCCAGGAGTCTCTTTGTACCCACTAGGCTTCCCTGATGACCATCTGTCTGTCC
GTCCCTGTTTTTGCTGTACATAACTCCTGCTGCACCCTCTCCCCGCACACCCGTCACCCATGAGAGAGAGAAACCTCTCTAGGGAAAGGC
AGGGTGGCTGCACCCAGCAACTAATCCAAATGGCAAATATTTTGTAACAAAATAGCCCAGAGGTATTTTATCTGTTCAATTCATAGAGTT

>99331_99331_7_WNK1-IQSEC3_WNK1_chr12_863490_ENST00000447667_IQSEC3_chr12_247433_ENST00000326261_length(amino acids)=1183AA_BP=300
MSVLSEASSGSARTRPAAVPCRPLRGRLGPSRPFRSRIRARSPLSSEPTMSGGAAEKQSSTPGSLFLSPPAPAPKNGSSSDSSVGEKLGA
AAADAVTGRTEEYRRRRHTMDKDSRGAAATTTTTEHRFFRRSVICDSNATALELPGLPLSLPQPSIPAAVPQSAPPEPHREETVTATATS
QVAQQPPAAAAPGEQAVAGPAPSTVPSSTSKDRPVSQPSLVGSKEEPPPARSGSGGGSAKEPQEERSQQQDDIEELETKAVGMSNDGRFL
KFDIEIGRGSFKTVYKGLDTETTVEVAWCELQIEMLEHKYGGHLVSRRAACTIQTAFRQYQLSKNFEKIRNSLLESRLPRRISLRKVRSP
TAESLAAEKALMEGYGLVGLPLVRSPSLPPTFAGTLTELEDSFTEQVQSLAKSIDDALSTWSLKTMCSLRESGAYQLHQALQAAAGPPGL
EAEGRAPESAGPGPGDDAAETPGLPPAHSGTLMMAFRDVTVQIANQNISVSSSTALSVANCLGAQTVQAPAEPAAGKAEQGETSGREAPE
APAVGREDASAEDSCAEAAASGAADGATAPKTEEEEEEEETAEVGRGAEAEAGDLEQLSSSSTSTKSAKSGSEASASASKDALQAMILSL
PRYHCENPASCKSPTLSTDTLRKRLYRIGLNLFNINPDKGIQFLISRGFIPDTPIGVAHFLLQRKGLSRQMIGEFLGNSKKQFNRDVLDC
VVDEMDFSSMELDEALRKFQAHIRVQGEAQKVERLIEAFSQRYCMCNPEVVQQFHNPDTIFILAFAIILLNTDMYSPNIKPDRKMMLEDF
IRNLRGVDDGADIPRELVVGIYERIQQKELKSNEDHVTYVTKVEKSIVGMKTVLSVPHRRLVCCSRLFEVTDVNKLQKQAAHQREVFLFN
DLLVILKLCPKKKSSSTYTFCKSVGLLGMQFQLFENEYYSHGITLVTPLSGSEKKQVLHFCALGSDEMQKFVEDLKESIAEVTELEQIRI
EWELEKQQGTKTLSFKPCGAQGDPQSKQGSPTAKREAALRERPAESTVEVSIHNRLQTSQHNSGLGAERGAPVPPPDLQPSPPRQQTPPL
PPPPPTPPGTLVQCQQIVKVIVLDKPCLARMEPLLSQALSCYTSSSSDSCGSTPLGGPGSPVKVTHQPPLPPPPPPYNHPHQFCPPGSLL

--------------------------------------------------------------
>99331_99331_8_WNK1-IQSEC3_WNK1_chr12_863490_ENST00000447667_IQSEC3_chr12_247433_ENST00000538872_length(transcript)=7342nt_BP=1269nt
CCACTCCTCTGCCCCGGGGCCGCCACCGCCCGGGCGTCGGACCTGGTCCCGTGCTCGCGGTGCCGCCGCCCTCTGGGCCTAGCCCGCCCA
GCTCGGCGAGCGGCGGCAGTGGGAGCCGCGTCCGCCGCATCCGCCTCGACTCGGTGCCGGCCCCTGGCCCTCCCCTCATGACTGCGGCGC
CTCTGCTGCCACCGCCCGCCCGGCCGCCGCTCGCCGCAGGATGGATGCGGACCGTGCGGCGCTAACCCCCGTGGCTCAGCTCCCGAATCG
CCCGCCTTCGAGCCCTCCTCGTGAGCCGCAGCAGCCTCGGTGCCAGCCCCCGCCGCAGCTGGGCCCAGCGGTCCGCCTGTCCCTCGTTGC
GGCTTGTCGGTGCTGAGTGAGGCGTCGTCCGGGTCGGCGCGAACCCGCCCGGCCGCGGTTCCCTGCAGACCTCTGCGCGGGCGGCTCGGC
CCTTCACGCCCTTTTCGTTCACGAATCCGAGCCCGCTCGCCTCTCTCCAGCGAACCGACCATGTCTGGCGGCGCCGCAGAGAAGCAGAGC
AGCACTCCCGGTTCCCTGTTCCTCTCGCCGCCGGCTCCTGCCCCCAAGAATGGCTCCAGCTCCGATTCCTCCGTGGGGGAGAAACTGGGA
GCCGCGGCCGCCGACGCTGTGACCGGCAGGACCGAGGAGTACAGGCGCCGCCGCCACACTATGGACAAGGACAGCCGTGGGGCGGCCGCG
ACCACTACCACCACTGAGCACCGCTTCTTCCGCCGGAGCGTCATCTGTGACTCCAATGCCACTGCACTGGAGCTTCCCGGCCTTCCTCTT
TCCCTGCCCCAGCCCAGCATCCCCGCGGCTGTCCCGCAGAGTGCTCCACCGGAGCCCCACCGGGAAGAGACCGTGACCGCCACCGCCACT
TCCCAGGTAGCCCAGCAGCCTCCAGCCGCTGCCGCCCCTGGGGAACAGGCCGTCGCGGGCCCTGCCCCCTCGACTGTCCCCAGCAGTACC
AGCAAAGACCGCCCAGTGTCCCAGCCTAGCCTTGTGGGGAGCAAAGAGGAGCCGCCGCCGGCGAGAAGTGGCAGCGGCGGCGGCAGCGCC
AAGGAGCCACAGGAGGAACGGAGCCAGCAGCAGGATGATATCGAAGAGCTGGAGACCAAGGCCGTGGGAATGTCTAACGATGGCCGCTTT
CTCAAGTTTGACATCGAAATCGGCAGAGGCTCCTTTAAGACGGTCTACAAAGGTCTGGACACTGAAACCACCGTGGAAGTCGCCTGGTGT
GAACTGCAGATTGAAATGCTAGAACATAAGTACGGCGGTCACCTGGTGTCCCGGCGCGCCGCTTGCACCATCCAAACCGCCTTCCGCCAA
TACCAGCTCAGCAAGAACTTCGAGAAAATCCGCAACTCGCTTCTGGAGAGCCGCCTGCCACGGCGGATCTCCCTGCGCAAGGTGCGGTCA
CCCACGGCCGAGAGCCTGGCGGCCGAGAAAGCGCTCATGGAGGGCTACGGCCTCGTGGGGCTGCCGCTGGTGCGCTCGCCCTCCCTGCCG
CCCACCTTCGCAGGCACCCTCACCGAGCTGGAGGACTCCTTCACCGAGCAGGTGCAATCCCTGGCCAAGTCCATCGACGACGCGCTCAGC
ACGTGGAGCCTCAAGACCATGTGCTCCCTGCGGGAGAGTGGCGCTTACCAGCTCCACCAGGCCCTGCAGGCGGCCGCGGGGCCCCCAGGC
CTGGAGGCCGAGGGGCGGGCGCCGGAGAGCGCGGGCCCCGGGCCCGGGGATGACGCCGCGGAGACCCCCGGCCTGCCCCCGGCCCACAGC
GGGACCCTCATGATGGCTTTCCGGGACGTCACGGTGCAGATCGCCAACCAGAACATATCCGTCTCCTCCTCCACGGCTCTGTCGGTGGCC
AACTGCCTGGGCGCTCAGACGGTCCAGGCCCCCGCAGAGCCCGCGGCGGGCAAGGCCGAGCAGGGCGAGACCTCTGGGCGGGAGGCCCCG
GAAGCCCCCGCCGTGGGCCGGGAGGACGCGTCAGCCGAGGACTCATGCGCAGAGGCTGCGGCTAGTGGGGCGGCGGATGGGGCCACAGCC
CCCAAAACAGAGGAGGAAGAGGAGGAGGAGGAGACGGCGGAGGTGGGGAGAGGGGCCGAGGCCGAGGCAGGCGACTTGGAGCAGCTGAGC
AGCAGCAGCACGTCCACCAAGTCCGCCAAGTCAGGCTCGGAGGCGTCGGCCTCCGCCTCCAAGGACGCCCTGCAGGCCATGATCCTGAGC
CTGCCGCGCTACCACTGCGAGAACCCAGCCAGCTGCAAGTCGCCCACGCTCTCCACCGACACCCTGCGCAAGCGGCTCTACCGCATCGGC
CTCAACCTCTTCAACATAAACCCCGACAAGGGCATCCAGTTCCTGATCTCACGCGGCTTCATCCCGGACACCCCCATCGGTGTGGCCCAT
TTCCTCCTCCAGCGAAAGGGCCTCAGCCGCCAGATGATTGGAGAGTTCCTGGGCAACAGCAAGAAGCAGTTCAACCGCGACGTGCTGGAC
TGCGTGGTGGACGAGATGGACTTCTCCAGCATGGAGCTGGACGAGGCCCTGCGCAAGTTCCAGGCACACATCCGTGTGCAGGGGGAGGCT
CAGAAGGTGGAGCGGCTCATTGAGGCCTTCAGCCAGCGCTACTGCATGTGCAACCCCGAAGTGGTTCAGCAGTTCCACAACCCCGACACC
ATCTTCATCCTCGCCTTCGCCATCATCCTCCTCAACACCGACATGTACAGCCCCAACATCAAGCCTGACCGGAAGATGATGCTGGAGGAC
TTCATCCGAAACCTTCGAGGTGTGGACGATGGCGCTGACATCCCCAGGGAGCTGGTGGTAGGCATCTATGAGAGGATACAGCAGAAGGAG
CTCAAGTCCAATGAGGACCACGTCACGTACGTCACCAAGGTGGAGAAGTCCATTGTGGGCATGAAGACAGTGCTGTCCGTGCCCCACCGC
CGCCTGGTGTGCTGCAGCCGGCTCTTCGAGGTGACGGATGTGAACAAGCTGCAGAAGCAGGCAGCGCATCAGAGGGAGGTGTTCCTCTTC
AATGACCTGCTGGTGATTCTCAAACTTTGCCCGAAGAAGAAGAGCTCCTCCACGTACACCTTTTGCAAGTCAGTTGGCCTGCTGGGCATG
CAGTTCCAGCTCTTTGAGAACGAGTATTACTCTCATGGCATCACACTGGTGACCCCGCTCTCGGGCTCCGAGAAGAAGCAGGTGCTGCAT
TTCTGTGCCCTGGGCTCGGACGAGATGCAGAAGTTCGTGGAGGACCTGAAGGAGTCCATTGCTGAGGTGACGGAGCTGGAGCAGATCCGA
ATAGAGTGGGAGCTGGAGAAGCAGCAGGGAACAAAGACACTCTCCTTCAAGCCCTGCGGAGCCCAGGGGGACCCACAGTCAAAGCAAGGA
TCGCCGACAGCCAAAAGGGAAGCCGCGCTCAGGGAGAGGCCGGCGGAGAGCACGGTGGAGGTGTCAATTCACAACAGGCTTCAAACGTCC
CAGCACAACTCCGGGCTGGGGGCCGAGAGGGGAGCGCCGGTGCCGCCGCCAGACCTGCAGCCTAGCCCCCCGAGACAGCAGACCCCACCA
CTGCCGCCGCCGCCACCCACGCCCCCGGGCACCCTGGTGCAGTGCCAGCAAATTGTCAAGGTCATTGTCCTGGACAAGCCCTGCCTGGCC
CGCATGGAGCCCCTGCTGAGCCAGGCTCTCTCCTGCTACACCTCGTCGTCCTCTGACTCCTGCGGCTCCACACCCCTGGGCGGTCCCGGC
TCTCCGGTCAAGGTCACCCACCAGCCTCCGCTGCCCCCGCCCCCACCCCCCTACAACCACCCTCACCAGTTCTGTCCCCCAGGCTCCCTG
CTGCACGGGCACCGCTACTCCAGTGGCTCAAGGAGCCTGGTGTAGACTCTGCCCCACCACCCTGCTGTCCTGGGAGGGCTGGCCACTGGG
GGGCCTGGGCTGCCCCTCCACTGCTCCCCATACCCTGGCACGATGCGTTCCTGGTCACTGATCACCATCATTTTGGGAAGAGAATCCCAA
TCCCTGGCACCTGGGTTTGCCTCATCCAACCATCCTTCCCTTTCTCAGCTGCACCCCCTCTGCAGATCTGAAGACACACCTCACTCTCCC
AGGGCCCTACACAGCCAGACCCGGCGAGGCCTCCTCTTCCCCTGGCCACCACTTTCCCCCATTGGACCATGGACTGAAGAAAACGAGCTG
AGGGTCTAACGAGCTTGCAGGCTTTGAGTCTGTTAGTGCCCGGGGCCTCGGGCCTTGGGCAGCAGCATGAGGCTGGGCCGGCCGGCAGTG
GAGCACTAGACAGAGTGGCTGGCTCGCAGCCCAGAACTAGTGCCTCTGTAGCTGCACTGAGGGGAGGAGGGTTGGTCCCACCCCTGGAGG
GACAGGTGGGAGGAGTGAGGAGGGGGCTTTTTCTGCCACCCCCGCCCCCAAGCCTGAAACTCTCAGGAGTCTACTTCTTGGTCCCCAGGG
ACATTGGCTGTCCTGACCATGTCCTTCCCCCTCCTCCCAGGGCCTCTGCTTCCTCAGGAGCTGCCCAGACTCCAGAAAAGCCTGGAAAAA
GGGAGGCGGGAAGGGGAGCACTTTCGGCTTTCTATAGGTCAGTCCAGCAGGGCCACGGGATCGCGAGGTCATGTATCTGCAAAATGCACC
TTTTTAAAGAGTGTCTTAGTTCCCCAGCCCCAGCTAATACCCGGCCAATGCCGTGTACGCACCGGCATGTGCACGCAAACACGCATGAGA
ACCAGGCCATTCCTTCCGCTGTGGAAGCAGAACTGGAGACGGGGCAGGAATGTGCCCAGCAGAGATGGGGCTCAGCCCGAGGCAGGGCTC
CCTCCTGCATGAGGCTCGGCCCGAGGCAGGGCTCCCTCCTGCATGAGTCTGTGGCCTCCAGGAGGGACTTGGGTGCAGATGTAAGCAAGA
AAAACCGGGGCTCCAGAGGCATGTGCATTTCCCCTGCGCCCCTCAGCCTTTAAATATTCCCTCCTCCTAGAAGGTTCTAGACCCCCCCCT
TCCAGCAGGGGTGCCCAAGAGTCCCTGGACCCTCAAAATTGCAAAGGAGACCCAAGCGGGGCTCGCTGACCTCCCAGGGCCCAGCAAGAT
GGGATAGCCAGCCTTAGGTGGCCCCACGAGCCCAAGCCTGGGGAAGGGCCCCTCCCCAGCCAGACGAGAGGCAGCCACCCCAGAGACCAC
AGGAGCCGTACCATGGCCTGCGCAGTCAGGCCCTATCAGGATGTGTCTGTCCCAAGCCTGGCCAGGCTCCAGTCCTGTGCCAGTAGCTCA
CTGCTGTCCTATGTGCAGGTCCCCCAACACTTGGAGCCTGTGGTTAAGGCCTCCTGGGAGAGGCAGTGAGCATGAGTCAAAGGTGACATG
GACTTGAATCTCCCCACCCCGCCCCGCCTGCAGTAGCCGGGCCAGGTAGGAGGCAAGGATCATTCCCTGCTCCCAGAGGTTCCAGATGAC
CTAGTTTCGTTTTGTGTGTGTGTGTGTGTGGTCACCCAGACGTCACTGTGATATCACCTAGTGAATCTATTTCTGGCCCTGTCTTCGTCG
GCCCAGTTTCTGTAACTTGCAGCCAATTTGCCCTCTCCCCTGTGGCTGCCAGCCCATCTGCCCCTCTGTGTCCTTGCTGCCCTGGCCCTC
CTCTGTTTTCTGTAACAGATGCTCCAGTCATTGCCTTTCAGAGTGGAGCAGATGACAGATGGGGTGCACGCATTCAGACACCTCTGATGC
CCTTAGCCAGGGCAGGGATCGTCCTTAAAGTGAAGGCCTGGACAGGAGGAGTCAGGGACTTGGGAGGAGGTGGAGCTGTGGGGATGGGAG
TGGAGGAATCAAAATGAGGGAAGCTGAAAATAGAATGAAAACGATGACTAAGAGGCAGGGAGTGCGAGGTATGGGGGAATAGGAACTATG
AGCTAAATATACTTATGGGGTGGGGGCCGTGGGGGCCAGGGACACTCTCCCAGACAGCCCTGACCCGCCAGGCAGGACCCCGTCCCCTGC
TCACACAGCTCTTCAAACTTACCAAGGACAGGCAGGACCCCGTCCCCTGCTCACACAGCTCTTCAAGCTTACCAAGGACAGGCAGAACCC
CGTCCCCTGCTCACACAGCTCTTCAAGCTTACCAAGGACAGGCAGGACCCCGTCCCCTGCTCACACAGCTCTTCAAACTTACCAAGTGCC
CTCTCCCCTGTTGAGGGCACAGCAACCCCAGGCCCTCCCTCCCACCTCAGCTGAAGCCCCAATCTTCCAAATCGGAACCAGCAAGTCTTA
GGGCTGGCACGCATCTGGGCCTCTAGCTGAGAACCCGGACTCTCAGGCACCTCAGTGCCCCTGCCCCAGGGCAGAGGCCCACCCCGTGGG
TTGGTGCAGTGGCTGCCCTGGGCTCCACGGGCAGCACAGGGAGTCTGTCCAGGAAGCAGCCCAGCCGGGGTCAGTATTCCGTGGAGCCAG
TCCTGAGCTGGGAGGGGCATTTAACACCCCTGAGGGCCTGGGGCAGGACACAGCTGGCCCTCCTCATTGTCAGGGGAAGCAAGTGCCCAA
CATCTGTAACCTCCCTTCCCTGCTCAGTCCCCAGGCCAAGGTTGGGACCCCTCTCCATCCCTGTCCCCAGAGCCTAGACCTCAGGGACCT
AGGAAAAGCCTCCTGCTCCCTCCCCACGGCAGCAGACAGGGCAGGGCCTCCAGCCCCCAGAGGGCCGGTGGGGGGTGCTCTCGGGCCTTC
CTGCTCTCCTAAGGTTGCGGGGACAGTAGAGTGCTGAGCCCCAGACCCAGTCACCCCAAGATGGCCCCACTCTATCCACTCTCTAGACCT
TTGGGAAATCTGGGTCCCTCTCCTGATTTGATCCATTCGGCCCCAACTCCAGAGTCGGGAATGGGAGATGAAACTAGTTTTCCACCCACT
TTTGGACAAGTCCCACCCCTAGATCTGAAGCAAGCTCTACCAGCAGCGTGTCCTGGAAGCCTGCCTGCCTGCCTGCCCGTCTGCACAGGT
GTCTTGATCCAGCCCTGCGTCTTCGAGCCCCTGTGCCACCGGTCCCCACGGCCCGCCAGGAGTCTCTTTGTACCCACTAGGCTTCCCTGA
TGACCATCTGTCTGTCCGTCCCTGTTTTTGCTGTACATAACTCCTGCTGCACCCTCTCCCCGCACACCCGTCACCCATGAGAGAGAGAAA
CCTCTCTAGGGAAAGGCAGGGTGGCTGCACCCAGCAACTAATCCAAATGGCAAATATTTTGTAACAAAATAGCCCAGAGGTATTTTATCT

>99331_99331_8_WNK1-IQSEC3_WNK1_chr12_863490_ENST00000447667_IQSEC3_chr12_247433_ENST00000538872_length(amino acids)=1183AA_BP=300
MSVLSEASSGSARTRPAAVPCRPLRGRLGPSRPFRSRIRARSPLSSEPTMSGGAAEKQSSTPGSLFLSPPAPAPKNGSSSDSSVGEKLGA
AAADAVTGRTEEYRRRRHTMDKDSRGAAATTTTTEHRFFRRSVICDSNATALELPGLPLSLPQPSIPAAVPQSAPPEPHREETVTATATS
QVAQQPPAAAAPGEQAVAGPAPSTVPSSTSKDRPVSQPSLVGSKEEPPPARSGSGGGSAKEPQEERSQQQDDIEELETKAVGMSNDGRFL
KFDIEIGRGSFKTVYKGLDTETTVEVAWCELQIEMLEHKYGGHLVSRRAACTIQTAFRQYQLSKNFEKIRNSLLESRLPRRISLRKVRSP
TAESLAAEKALMEGYGLVGLPLVRSPSLPPTFAGTLTELEDSFTEQVQSLAKSIDDALSTWSLKTMCSLRESGAYQLHQALQAAAGPPGL
EAEGRAPESAGPGPGDDAAETPGLPPAHSGTLMMAFRDVTVQIANQNISVSSSTALSVANCLGAQTVQAPAEPAAGKAEQGETSGREAPE
APAVGREDASAEDSCAEAAASGAADGATAPKTEEEEEEEETAEVGRGAEAEAGDLEQLSSSSTSTKSAKSGSEASASASKDALQAMILSL
PRYHCENPASCKSPTLSTDTLRKRLYRIGLNLFNINPDKGIQFLISRGFIPDTPIGVAHFLLQRKGLSRQMIGEFLGNSKKQFNRDVLDC
VVDEMDFSSMELDEALRKFQAHIRVQGEAQKVERLIEAFSQRYCMCNPEVVQQFHNPDTIFILAFAIILLNTDMYSPNIKPDRKMMLEDF
IRNLRGVDDGADIPRELVVGIYERIQQKELKSNEDHVTYVTKVEKSIVGMKTVLSVPHRRLVCCSRLFEVTDVNKLQKQAAHQREVFLFN
DLLVILKLCPKKKSSSTYTFCKSVGLLGMQFQLFENEYYSHGITLVTPLSGSEKKQVLHFCALGSDEMQKFVEDLKESIAEVTELEQIRI
EWELEKQQGTKTLSFKPCGAQGDPQSKQGSPTAKREAALRERPAESTVEVSIHNRLQTSQHNSGLGAERGAPVPPPDLQPSPPRQQTPPL
PPPPPTPPGTLVQCQQIVKVIVLDKPCLARMEPLLSQALSCYTSSSSDSCGSTPLGGPGSPVKVTHQPPLPPPPPPYNHPHQFCPPGSLL

--------------------------------------------------------------
>99331_99331_9_WNK1-IQSEC3_WNK1_chr12_863490_ENST00000530271_IQSEC3_chr12_247432_ENST00000326261_length(transcript)=6719nt_BP=759nt
ATGTCTGGCGGCGCCGCAGAGAAGCAGAGCAGCACTCCCGGTTCCCTGTTCCTCTCGCCGCCGGCTCCTGCCCCCAAGAATGGCTCCAGC
TCCGATTCCTCCGTGGGGGAGAAACTGGGAGCCGCGGCCGCCGACGCTGTGACCGGCAGGACCGAGGAGTACAGGCGCCGCCGCCACACT
ATGGACAAGGACAGCCGTGGGGCGGCCGCGACCACTACCACCACTGAGCACCGCTTCTTCCGCCGGAGCGTCATCTGTGACTCCAATGCC
ACTGCACTGGAGCTTCCCGGCCTTCCTCTTTCCCTGCCCCAGCCCAGCATCCCCGCGGCTGTCCCGCAGAGTGCTCCACCGGAGCCCCAC
CGGGAAGAGACCGTGACCGCCACCGCCACTTCCCAGGTAGCCCAGCAGCCTCCAGCCGCTGCCGCCCCTGGGGAACAGGCCGTCGCGGGC
CCTGCCCCCTCGACTGTCCCCAGCAGTACCAGCAAAGACCGCCCAGTGTCCCAGCCTAGCCTTGTGGGGAGCAAAGAGGAGCCGCCGCCG
GCGAGAAGTGGCAGCGGCGGCGGCAGCGCCAAGGAGCCACAGGAGGAACGGAGCCAGCAGCAGGATGATATCGAAGAGCTGGAGACCAAG
GCCGTGGGAATGTCTAACGATGGCCGCTTTCTCAAGTTTGACATCGAAATCGGCAGAGGCTCCTTTAAGACGGTCTACAAAGGTCTGGAC
ACTGAAACCACCGTGGAAGTCGCCTGGTGTGAACTGCAGATTGAAATGCTAGAACATAAGTACGGCGGTCACCTGGTGTCCCGGCGCGCC
GCTTGCACCATCCAAACCGCCTTCCGCCAATACCAGCTCAGCAAGAACTTCGAGAAAATCCGCAACTCGCTTCTGGAGAGCCGCCTGCCA
CGGCGGATCTCCCTGCGCAAGGTGCGGTCACCCACGGCCGAGAGCCTGGCGGCCGAGAAAGCGCTCATGGAGGGCTACGGCCTCGTGGGG
CTGCCGCTGGTGCGCTCGCCCTCCCTGCCGCCCACCTTCGCAGGCACCCTCACCGAGCTGGAGGACTCCTTCACCGAGCAGGTGCAATCC
CTGGCCAAGTCCATCGACGACGCGCTCAGCACGTGGAGCCTCAAGACCATGTGCTCCCTGCGGGAGAGTGGCGCTTACCAGCTCCACCAG
GCCCTGCAGGCGGCCGCGGGGCCCCCAGGCCTGGAGGCCGAGGGGCGGGCGCCGGAGAGCGCGGGCCCCGGGCCCGGGGATGACGCCGCG
GAGACCCCCGGCCTGCCCCCGGCCCACAGCGGGACCCTCATGATGGCTTTCCGGGACGTCACGGTGCAGATCGCCAACCAGAACATATCC
GTCTCCTCCTCCACGGCTCTGTCGGTGGCCAACTGCCTGGGCGCTCAGACGGTCCAGGCCCCCGCAGAGCCCGCGGCGGGCAAGGCCGAG
CAGGGCGAGACCTCTGGGCGGGAGGCCCCGGAAGCCCCCGCCGTGGGCCGGGAGGACGCGTCAGCCGAGGACTCATGCGCAGAGGCTGCG
GCTAGTGGGGCGGCGGATGGGGCCACAGCCCCCAAAACAGAGGAGGAAGAGGAGGAGGAGGAGACGGCGGAGGTGGGGAGAGGGGCCGAG
GCCGAGGCAGGCGACTTGGAGCAGCTGAGCAGCAGCAGCACGTCCACCAAGTCCGCCAAGTCAGGCTCGGAGGCGTCGGCCTCCGCCTCC
AAGGACGCCCTGCAGGCCATGATCCTGAGCCTGCCGCGCTACCACTGCGAGAACCCAGCCAGCTGCAAGTCGCCCACGCTCTCCACCGAC
ACCCTGCGCAAGCGGCTCTACCGCATCGGCCTCAACCTCTTCAACATAAACCCCGACAAGGGCATCCAGTTCCTGATCTCACGCGGCTTC
ATCCCGGACACCCCCATCGGTGTGGCCCATTTCCTCCTCCAGCGAAAGGGCCTCAGCCGCCAGATGATTGGAGAGTTCCTGGGCAACAGC
AAGAAGCAGTTCAACCGCGACGTGCTGGACTGCGTGGTGGACGAGATGGACTTCTCCAGCATGGAGCTGGACGAGGCCCTGCGCAAGTTC
CAGGCACACATCCGTGTGCAGGGGGAGGCTCAGAAGGTGGAGCGGCTCATTGAGGCCTTCAGCCAGCGCTACTGCATGTGCAACCCCGAA
GTGGTTCAGCAGTTCCACAACCCCGACACCATCTTCATCCTCGCCTTCGCCATCATCCTCCTCAACACCGACATGTACAGCCCCAACATC
AAGCCTGACCGGAAGATGATGCTGGAGGACTTCATCCGAAACCTTCGAGGTGTGGACGATGGCGCTGACATCCCCAGGGAGCTGGTGGTA
GGCATCTATGAGAGGATACAGCAGAAGGAGCTCAAGTCCAATGAGGACCACGTCACGTACGTCACCAAGGTGGAGAAGTCCATTGTGGGC
ATGAAGACAGTGCTGTCCGTGCCCCACCGCCGCCTGGTGTGCTGCAGCCGGCTCTTCGAGGTGACGGATGTGAACAAGCTGCAGAAGCAG
GCAGCGCATCAGAGGGAGGTGTTCCTCTTCAATGACCTGCTGGTGATTCTCAAACTTTGCCCGAAGAAGAAGAGCTCCTCCACGTACACC
TTTTGCAAGTCAGTTGGCCTGCTGGGCATGCAGTTCCAGCTCTTTGAGAACGAGTATTACTCTCATGGCATCACACTGGTGACCCCGCTC
TCGGGCTCCGAGAAGAAGCAGGTGCTGCATTTCTGTGCCCTGGGCTCGGACGAGATGCAGAAGTTCGTGGAGGACCTGAAGGAGTCCATT
GCTGAGGTGACGGAGCTGGAGCAGATCCGAATAGAGTGGGAGCTGGAGAAGCAGCAGGGAACAAAGACACTCTCCTTCAAGCCCTGCGGA
GCCCAGGGGGACCCACAGTCAAAGCAAGGATCGCCGACAGCCAAAAGGGAAGCCGCGCTCAGGGAGAGGCCGGCGGAGAGCACGGTGGAG
GTGTCAATTCACAACAGGCTTCAAACGTCCCAGCACAACTCCGGGCTGGGGGCCGAGAGGGGAGCGCCGGTGCCGCCGCCAGACCTGCAG
CCTAGCCCCCCGAGACAGCAGACCCCACCACTGCCGCCGCCGCCACCCACGCCCCCGGGCACCCTGGTGCAGTGCCAGCAAATTGTCAAG
GTCATTGTCCTGGACAAGCCCTGCCTGGCCCGCATGGAGCCCCTGCTGAGCCAGGCTCTCTCCTGCTACACCTCGTCGTCCTCTGACTCC
TGCGGCTCCACACCCCTGGGCGGTCCCGGCTCTCCGGTCAAGGTCACCCACCAGCCTCCGCTGCCCCCGCCCCCACCCCCCTACAACCAC
CCTCACCAGTTCTGTCCCCCAGGCTCCCTGCTGCACGGGCACCGCTACTCCAGTGGCTCAAGGAGCCTGGTGTAGACTCTGCCCCACCAC
CCTGCTGTCCTGGGAGGGCTGGCCACTGGGGGGCCTGGGCTGCCCCTCCACTGCTCCCCATACCCTGGCACGATGCGTTCCTGGTCACTG
ATCACCATCATTTTGGGAAGAGAATCCCAATCCCTGGCACCTGGGTTTGCCTCATCCAACCATCCTTCCCTTTCTCAGCTGCACCCCCTC
TGCAGATCTGAAGACACACCTCACTCTCCCAGGGCCCTACACAGCCAGACCCGGCGAGGCCTCCTCTTCCCCTGGCCACCACTTTCCCCC
ATTGGACCATGGACTGAAGAAAACGAGCTGAGGGTCTAACGAGCTTGCAGGCTTTGAGTCTGTTAGTGCCCGGGGCCTCGGGCCTTGGGC
AGCAGCATGAGGCTGGGCCGGCCGGCAGTGGAGCACTAGACAGAGTGGCTGGCTCGCAGCCCAGAACTAGTGCCTCTGTAGCTGCACTGA
GGGGAGGAGGGTTGGTCCCACCCCTGGAGGGACAGGTGGGAGGAGTGAGGAGGGGGCTTTTTCTGCCACCCCCGCCCCCAAGCCTGAAAC
TCTCAGGAGTCTACTTCTTGGTCCCCAGGGACATTGGCTGTCCTGACCATGTCCTTCCCCCTCCTCCCAGGGCCTCTGCTTCCTCAGGAG
CTGCCCAGACTCCAGAAAAGCCTGGAAAAAGGGAGGCGGGAAGGGGAGCACTTTCGGCTTTCTATAGGTCAGTCCAGCAGGGCCACGGGA
TCGCGAGGTCATGTATCTGCAAAATGCACCTTTTTAAAGAGTGTCTTAGTTCCCCAGCCCCAGCTAATACCCGGCCAATGCCGTGTACGC
ACCGGCATGTGCACGCAAACACGCATGAGAACCAGGCCATTCCTTCCGCTGTGGAAGCAGAACTGGAGACGGGGCAGGAATGTGCCCAGC
AGAGATGGGGCTCAGCCCGAGGCAGGGCTCCCTCCTGCATGAGGCTCGGCCCGAGGCAGGGCTCCCTCCTGCATGAGTCTGTGGCCTCCA
GGAGGGACTTGGGTGCAGATGTAAGCAAGAAAAACCGGGGCTCCAGAGGCATGTGCATTTCCCCTGCGCCCCTCAGCCTTTAAATATTCC
CTCCTCCTAGAAGGTTCTAGACCCCCCCCTTCCAGCAGGGGTGCCCAAGAGTCCCTGGACCCTCAAAATTGCAAAGGAGACCCAAGCGGG
GCTCGCTGACCTCCCAGGGCCCAGCAAGATGGGATAGCCAGCCTTAGGTGGCCCCACGAGCCCAAGCCTGGGGAAGGGCCCCTCCCCAGC
CAGACGAGAGGCAGCCACCCCAGAGACCACAGGAGCCGTACCATGGCCTGCGCAGTCAGGCCCTATCAGGATGTGTCTGTCCCAAGCCTG
GCCAGGCTCCAGTCCTGTGCCAGTAGCTCACTGCTGTCCTATGTGCAGGTCCCCCAACACTTGGAGCCTGTGGTTAAGGCCTCCTGGGAG
AGGCAGTGAGCATGAGTCAAAGGTGACATGGACTTGAATCTCCCCACCCCGCCCCGCCTGCAGTAGCCGGGCCAGGTAGGAGGCAAGGAT
CATTCCCTGCTCCCAGAGGTTCCAGATGACCTAGTTTCGTTTTGTGTGTGTGTGTGTGTGGTCACCCAGACGTCACTGTGATATCACCTA
GTGAATCTATTTCTGGCCCTGTCTTCGTCGGCCCAGTTTCTGTAACTTGCAGCCAATTTGCCCTCTCCCCTGTGGCTGCCAGCCCATCTG
CCCCTCTGTGTCCTTGCTGCCCTGGCCCTCCTCTGTTTTCTGTAACAGATGCTCCAGTCATTGCCTTTCAGAGTGGAGCAGATGACAGAT
GGGGTGCACGCATTCAGACACCTCTGATGCCCTTAGCCAGGGCAGGGATCGTCCTTAAAGTGAAGGCCTGGACAGGAGGAGTCAGGGACT
TGGGAGGAGGTGGAGCTGTGGGGATGGGAGTGGAGGAATCAAAATGAGGGAAGCTGAAAATAGAATGAAAACGATGACTAAGAGGCAGGG
AGTGCGAGGTATGGGGGAATAGGAACTATGAGCTAAATATACTTATGGGGTGGGGGCCGTGGGGGCCAGGGACACTCTCCCAGACAGCCC
TGACCCGCCAGGCAGGACCCCGTCCCCTGCTCACACAGCTCTTCAAACTTACCAAGGACAGGCAGGACCCCGTCCCCTGCTCACACAGCT
CTTCAAGCTTACCAAGTCCCCTGTTGAGGGCACAGCAACCCCAGGCCCTCCCTCCCACCTCAGCTGAAGCCCCAATCTTCCAAATCGGAA
CCAGCAAGTCTTAGGGCTGGCACGCATCTGGGCCTCTAGCTGAGAACCCGGACTCTCAGGCACCTCAGTGCCCCTGCCCCAGGGCAGAGG
CCCACCCCGTGGGTTGGTGCAGTGGCTGCCCTGGGCTCCACGGGCAGCACAGGGAGTCTGTCCAGGAAGCAGCCCAGCCGGGGTCAGTAT
TCCGTGGAGCCAGTCCTGAGCTGGGAGGGGCATTTAACACCCCTGAGGGCCTGGGGCAGGACACAGCTGGCCCTCCTCATTGTCAGGGGA
AGCAAGTGCCCAACATCTGTAACCTCCCTTCCCTGCTCAGTCCCCAGGCCAAGGTTGGGACCCCTCTCCATCCCTGTCCCCAGAGCCTAG
ACCTCAGGGACCTAGGAAAAGCCTCCTGCTCCCTCCCCACGGCAGCAGACAGGGCAGGGCCTCCAGCCCCCAGAGGGCCGGTGGGGGGTG
CTCTCGGGCCTTCCTGCTCTCCTAAGGTTGCGGGGACAGTAGAGTGCTGAGCCCCAGACCCAGTCACCCCAAGATGGCCCCACTCTATCC
ACTCTCTAGACCTTTGGGAAATCTGGGTCCCTCTCCTGATTTGATCCATTCGGCCCCAACTCCAGAGTCGGGAATGGGAGATGAAACTAG
TTTTCCACCCACTTTTGGACAAGTCCCACCCCTAGATCTGAAGCAAGCTCTACCAGCAGCGTGTCCTGGAAGCCTGCCTGCCTGCCTGCC
CGTCTGCACAGGTGTCTTGATCCAGCCCTGCGTCTTCGAGCCCCTGTGCCACCGGTCCCCACGGCCCGCCAGGAGTCTCTTTGTACCCAC
TAGGCTTCCCTGATGACCATCTGTCTGTCCGTCCCTGTTTTTGCTGTACATAACTCCTGCTGCACCCTCTCCCCGCACACCCGTCACCCA
TGAGAGAGAGAAACCTCTCTAGGGAAAGGCAGGGTGGCTGCACCCAGCAACTAATCCAAATGGCAAATATTTTGTAACAAAATAGCCCAG

>99331_99331_9_WNK1-IQSEC3_WNK1_chr12_863490_ENST00000530271_IQSEC3_chr12_247432_ENST00000326261_length(amino acids)=1134AA_BP=251
MSGGAAEKQSSTPGSLFLSPPAPAPKNGSSSDSSVGEKLGAAAADAVTGRTEEYRRRRHTMDKDSRGAAATTTTTEHRFFRRSVICDSNA
TALELPGLPLSLPQPSIPAAVPQSAPPEPHREETVTATATSQVAQQPPAAAAPGEQAVAGPAPSTVPSSTSKDRPVSQPSLVGSKEEPPP
ARSGSGGGSAKEPQEERSQQQDDIEELETKAVGMSNDGRFLKFDIEIGRGSFKTVYKGLDTETTVEVAWCELQIEMLEHKYGGHLVSRRA
ACTIQTAFRQYQLSKNFEKIRNSLLESRLPRRISLRKVRSPTAESLAAEKALMEGYGLVGLPLVRSPSLPPTFAGTLTELEDSFTEQVQS
LAKSIDDALSTWSLKTMCSLRESGAYQLHQALQAAAGPPGLEAEGRAPESAGPGPGDDAAETPGLPPAHSGTLMMAFRDVTVQIANQNIS
VSSSTALSVANCLGAQTVQAPAEPAAGKAEQGETSGREAPEAPAVGREDASAEDSCAEAAASGAADGATAPKTEEEEEEEETAEVGRGAE
AEAGDLEQLSSSSTSTKSAKSGSEASASASKDALQAMILSLPRYHCENPASCKSPTLSTDTLRKRLYRIGLNLFNINPDKGIQFLISRGF
IPDTPIGVAHFLLQRKGLSRQMIGEFLGNSKKQFNRDVLDCVVDEMDFSSMELDEALRKFQAHIRVQGEAQKVERLIEAFSQRYCMCNPE
VVQQFHNPDTIFILAFAIILLNTDMYSPNIKPDRKMMLEDFIRNLRGVDDGADIPRELVVGIYERIQQKELKSNEDHVTYVTKVEKSIVG
MKTVLSVPHRRLVCCSRLFEVTDVNKLQKQAAHQREVFLFNDLLVILKLCPKKKSSSTYTFCKSVGLLGMQFQLFENEYYSHGITLVTPL
SGSEKKQVLHFCALGSDEMQKFVEDLKESIAEVTELEQIRIEWELEKQQGTKTLSFKPCGAQGDPQSKQGSPTAKREAALRERPAESTVE
VSIHNRLQTSQHNSGLGAERGAPVPPPDLQPSPPRQQTPPLPPPPPTPPGTLVQCQQIVKVIVLDKPCLARMEPLLSQALSCYTSSSSDS

--------------------------------------------------------------
>99331_99331_10_WNK1-IQSEC3_WNK1_chr12_863490_ENST00000530271_IQSEC3_chr12_247432_ENST00000538872_length(transcript)=6832nt_BP=759nt
ATGTCTGGCGGCGCCGCAGAGAAGCAGAGCAGCACTCCCGGTTCCCTGTTCCTCTCGCCGCCGGCTCCTGCCCCCAAGAATGGCTCCAGC
TCCGATTCCTCCGTGGGGGAGAAACTGGGAGCCGCGGCCGCCGACGCTGTGACCGGCAGGACCGAGGAGTACAGGCGCCGCCGCCACACT
ATGGACAAGGACAGCCGTGGGGCGGCCGCGACCACTACCACCACTGAGCACCGCTTCTTCCGCCGGAGCGTCATCTGTGACTCCAATGCC
ACTGCACTGGAGCTTCCCGGCCTTCCTCTTTCCCTGCCCCAGCCCAGCATCCCCGCGGCTGTCCCGCAGAGTGCTCCACCGGAGCCCCAC
CGGGAAGAGACCGTGACCGCCACCGCCACTTCCCAGGTAGCCCAGCAGCCTCCAGCCGCTGCCGCCCCTGGGGAACAGGCCGTCGCGGGC
CCTGCCCCCTCGACTGTCCCCAGCAGTACCAGCAAAGACCGCCCAGTGTCCCAGCCTAGCCTTGTGGGGAGCAAAGAGGAGCCGCCGCCG
GCGAGAAGTGGCAGCGGCGGCGGCAGCGCCAAGGAGCCACAGGAGGAACGGAGCCAGCAGCAGGATGATATCGAAGAGCTGGAGACCAAG
GCCGTGGGAATGTCTAACGATGGCCGCTTTCTCAAGTTTGACATCGAAATCGGCAGAGGCTCCTTTAAGACGGTCTACAAAGGTCTGGAC
ACTGAAACCACCGTGGAAGTCGCCTGGTGTGAACTGCAGATTGAAATGCTAGAACATAAGTACGGCGGTCACCTGGTGTCCCGGCGCGCC
GCTTGCACCATCCAAACCGCCTTCCGCCAATACCAGCTCAGCAAGAACTTCGAGAAAATCCGCAACTCGCTTCTGGAGAGCCGCCTGCCA
CGGCGGATCTCCCTGCGCAAGGTGCGGTCACCCACGGCCGAGAGCCTGGCGGCCGAGAAAGCGCTCATGGAGGGCTACGGCCTCGTGGGG
CTGCCGCTGGTGCGCTCGCCCTCCCTGCCGCCCACCTTCGCAGGCACCCTCACCGAGCTGGAGGACTCCTTCACCGAGCAGGTGCAATCC
CTGGCCAAGTCCATCGACGACGCGCTCAGCACGTGGAGCCTCAAGACCATGTGCTCCCTGCGGGAGAGTGGCGCTTACCAGCTCCACCAG
GCCCTGCAGGCGGCCGCGGGGCCCCCAGGCCTGGAGGCCGAGGGGCGGGCGCCGGAGAGCGCGGGCCCCGGGCCCGGGGATGACGCCGCG
GAGACCCCCGGCCTGCCCCCGGCCCACAGCGGGACCCTCATGATGGCTTTCCGGGACGTCACGGTGCAGATCGCCAACCAGAACATATCC
GTCTCCTCCTCCACGGCTCTGTCGGTGGCCAACTGCCTGGGCGCTCAGACGGTCCAGGCCCCCGCAGAGCCCGCGGCGGGCAAGGCCGAG
CAGGGCGAGACCTCTGGGCGGGAGGCCCCGGAAGCCCCCGCCGTGGGCCGGGAGGACGCGTCAGCCGAGGACTCATGCGCAGAGGCTGCG
GCTAGTGGGGCGGCGGATGGGGCCACAGCCCCCAAAACAGAGGAGGAAGAGGAGGAGGAGGAGACGGCGGAGGTGGGGAGAGGGGCCGAG
GCCGAGGCAGGCGACTTGGAGCAGCTGAGCAGCAGCAGCACGTCCACCAAGTCCGCCAAGTCAGGCTCGGAGGCGTCGGCCTCCGCCTCC
AAGGACGCCCTGCAGGCCATGATCCTGAGCCTGCCGCGCTACCACTGCGAGAACCCAGCCAGCTGCAAGTCGCCCACGCTCTCCACCGAC
ACCCTGCGCAAGCGGCTCTACCGCATCGGCCTCAACCTCTTCAACATAAACCCCGACAAGGGCATCCAGTTCCTGATCTCACGCGGCTTC
ATCCCGGACACCCCCATCGGTGTGGCCCATTTCCTCCTCCAGCGAAAGGGCCTCAGCCGCCAGATGATTGGAGAGTTCCTGGGCAACAGC
AAGAAGCAGTTCAACCGCGACGTGCTGGACTGCGTGGTGGACGAGATGGACTTCTCCAGCATGGAGCTGGACGAGGCCCTGCGCAAGTTC
CAGGCACACATCCGTGTGCAGGGGGAGGCTCAGAAGGTGGAGCGGCTCATTGAGGCCTTCAGCCAGCGCTACTGCATGTGCAACCCCGAA
GTGGTTCAGCAGTTCCACAACCCCGACACCATCTTCATCCTCGCCTTCGCCATCATCCTCCTCAACACCGACATGTACAGCCCCAACATC
AAGCCTGACCGGAAGATGATGCTGGAGGACTTCATCCGAAACCTTCGAGGTGTGGACGATGGCGCTGACATCCCCAGGGAGCTGGTGGTA
GGCATCTATGAGAGGATACAGCAGAAGGAGCTCAAGTCCAATGAGGACCACGTCACGTACGTCACCAAGGTGGAGAAGTCCATTGTGGGC
ATGAAGACAGTGCTGTCCGTGCCCCACCGCCGCCTGGTGTGCTGCAGCCGGCTCTTCGAGGTGACGGATGTGAACAAGCTGCAGAAGCAG
GCAGCGCATCAGAGGGAGGTGTTCCTCTTCAATGACCTGCTGGTGATTCTCAAACTTTGCCCGAAGAAGAAGAGCTCCTCCACGTACACC
TTTTGCAAGTCAGTTGGCCTGCTGGGCATGCAGTTCCAGCTCTTTGAGAACGAGTATTACTCTCATGGCATCACACTGGTGACCCCGCTC
TCGGGCTCCGAGAAGAAGCAGGTGCTGCATTTCTGTGCCCTGGGCTCGGACGAGATGCAGAAGTTCGTGGAGGACCTGAAGGAGTCCATT
GCTGAGGTGACGGAGCTGGAGCAGATCCGAATAGAGTGGGAGCTGGAGAAGCAGCAGGGAACAAAGACACTCTCCTTCAAGCCCTGCGGA
GCCCAGGGGGACCCACAGTCAAAGCAAGGATCGCCGACAGCCAAAAGGGAAGCCGCGCTCAGGGAGAGGCCGGCGGAGAGCACGGTGGAG
GTGTCAATTCACAACAGGCTTCAAACGTCCCAGCACAACTCCGGGCTGGGGGCCGAGAGGGGAGCGCCGGTGCCGCCGCCAGACCTGCAG
CCTAGCCCCCCGAGACAGCAGACCCCACCACTGCCGCCGCCGCCACCCACGCCCCCGGGCACCCTGGTGCAGTGCCAGCAAATTGTCAAG
GTCATTGTCCTGGACAAGCCCTGCCTGGCCCGCATGGAGCCCCTGCTGAGCCAGGCTCTCTCCTGCTACACCTCGTCGTCCTCTGACTCC
TGCGGCTCCACACCCCTGGGCGGTCCCGGCTCTCCGGTCAAGGTCACCCACCAGCCTCCGCTGCCCCCGCCCCCACCCCCCTACAACCAC
CCTCACCAGTTCTGTCCCCCAGGCTCCCTGCTGCACGGGCACCGCTACTCCAGTGGCTCAAGGAGCCTGGTGTAGACTCTGCCCCACCAC
CCTGCTGTCCTGGGAGGGCTGGCCACTGGGGGGCCTGGGCTGCCCCTCCACTGCTCCCCATACCCTGGCACGATGCGTTCCTGGTCACTG
ATCACCATCATTTTGGGAAGAGAATCCCAATCCCTGGCACCTGGGTTTGCCTCATCCAACCATCCTTCCCTTTCTCAGCTGCACCCCCTC
TGCAGATCTGAAGACACACCTCACTCTCCCAGGGCCCTACACAGCCAGACCCGGCGAGGCCTCCTCTTCCCCTGGCCACCACTTTCCCCC
ATTGGACCATGGACTGAAGAAAACGAGCTGAGGGTCTAACGAGCTTGCAGGCTTTGAGTCTGTTAGTGCCCGGGGCCTCGGGCCTTGGGC
AGCAGCATGAGGCTGGGCCGGCCGGCAGTGGAGCACTAGACAGAGTGGCTGGCTCGCAGCCCAGAACTAGTGCCTCTGTAGCTGCACTGA
GGGGAGGAGGGTTGGTCCCACCCCTGGAGGGACAGGTGGGAGGAGTGAGGAGGGGGCTTTTTCTGCCACCCCCGCCCCCAAGCCTGAAAC
TCTCAGGAGTCTACTTCTTGGTCCCCAGGGACATTGGCTGTCCTGACCATGTCCTTCCCCCTCCTCCCAGGGCCTCTGCTTCCTCAGGAG
CTGCCCAGACTCCAGAAAAGCCTGGAAAAAGGGAGGCGGGAAGGGGAGCACTTTCGGCTTTCTATAGGTCAGTCCAGCAGGGCCACGGGA
TCGCGAGGTCATGTATCTGCAAAATGCACCTTTTTAAAGAGTGTCTTAGTTCCCCAGCCCCAGCTAATACCCGGCCAATGCCGTGTACGC
ACCGGCATGTGCACGCAAACACGCATGAGAACCAGGCCATTCCTTCCGCTGTGGAAGCAGAACTGGAGACGGGGCAGGAATGTGCCCAGC
AGAGATGGGGCTCAGCCCGAGGCAGGGCTCCCTCCTGCATGAGGCTCGGCCCGAGGCAGGGCTCCCTCCTGCATGAGTCTGTGGCCTCCA
GGAGGGACTTGGGTGCAGATGTAAGCAAGAAAAACCGGGGCTCCAGAGGCATGTGCATTTCCCCTGCGCCCCTCAGCCTTTAAATATTCC
CTCCTCCTAGAAGGTTCTAGACCCCCCCCTTCCAGCAGGGGTGCCCAAGAGTCCCTGGACCCTCAAAATTGCAAAGGAGACCCAAGCGGG
GCTCGCTGACCTCCCAGGGCCCAGCAAGATGGGATAGCCAGCCTTAGGTGGCCCCACGAGCCCAAGCCTGGGGAAGGGCCCCTCCCCAGC
CAGACGAGAGGCAGCCACCCCAGAGACCACAGGAGCCGTACCATGGCCTGCGCAGTCAGGCCCTATCAGGATGTGTCTGTCCCAAGCCTG
GCCAGGCTCCAGTCCTGTGCCAGTAGCTCACTGCTGTCCTATGTGCAGGTCCCCCAACACTTGGAGCCTGTGGTTAAGGCCTCCTGGGAG
AGGCAGTGAGCATGAGTCAAAGGTGACATGGACTTGAATCTCCCCACCCCGCCCCGCCTGCAGTAGCCGGGCCAGGTAGGAGGCAAGGAT
CATTCCCTGCTCCCAGAGGTTCCAGATGACCTAGTTTCGTTTTGTGTGTGTGTGTGTGTGGTCACCCAGACGTCACTGTGATATCACCTA
GTGAATCTATTTCTGGCCCTGTCTTCGTCGGCCCAGTTTCTGTAACTTGCAGCCAATTTGCCCTCTCCCCTGTGGCTGCCAGCCCATCTG
CCCCTCTGTGTCCTTGCTGCCCTGGCCCTCCTCTGTTTTCTGTAACAGATGCTCCAGTCATTGCCTTTCAGAGTGGAGCAGATGACAGAT
GGGGTGCACGCATTCAGACACCTCTGATGCCCTTAGCCAGGGCAGGGATCGTCCTTAAAGTGAAGGCCTGGACAGGAGGAGTCAGGGACT
TGGGAGGAGGTGGAGCTGTGGGGATGGGAGTGGAGGAATCAAAATGAGGGAAGCTGAAAATAGAATGAAAACGATGACTAAGAGGCAGGG
AGTGCGAGGTATGGGGGAATAGGAACTATGAGCTAAATATACTTATGGGGTGGGGGCCGTGGGGGCCAGGGACACTCTCCCAGACAGCCC
TGACCCGCCAGGCAGGACCCCGTCCCCTGCTCACACAGCTCTTCAAACTTACCAAGGACAGGCAGGACCCCGTCCCCTGCTCACACAGCT
CTTCAAGCTTACCAAGGACAGGCAGAACCCCGTCCCCTGCTCACACAGCTCTTCAAGCTTACCAAGGACAGGCAGGACCCCGTCCCCTGC
TCACACAGCTCTTCAAACTTACCAAGTGCCCTCTCCCCTGTTGAGGGCACAGCAACCCCAGGCCCTCCCTCCCACCTCAGCTGAAGCCCC
AATCTTCCAAATCGGAACCAGCAAGTCTTAGGGCTGGCACGCATCTGGGCCTCTAGCTGAGAACCCGGACTCTCAGGCACCTCAGTGCCC
CTGCCCCAGGGCAGAGGCCCACCCCGTGGGTTGGTGCAGTGGCTGCCCTGGGCTCCACGGGCAGCACAGGGAGTCTGTCCAGGAAGCAGC
CCAGCCGGGGTCAGTATTCCGTGGAGCCAGTCCTGAGCTGGGAGGGGCATTTAACACCCCTGAGGGCCTGGGGCAGGACACAGCTGGCCC
TCCTCATTGTCAGGGGAAGCAAGTGCCCAACATCTGTAACCTCCCTTCCCTGCTCAGTCCCCAGGCCAAGGTTGGGACCCCTCTCCATCC
CTGTCCCCAGAGCCTAGACCTCAGGGACCTAGGAAAAGCCTCCTGCTCCCTCCCCACGGCAGCAGACAGGGCAGGGCCTCCAGCCCCCAG
AGGGCCGGTGGGGGGTGCTCTCGGGCCTTCCTGCTCTCCTAAGGTTGCGGGGACAGTAGAGTGCTGAGCCCCAGACCCAGTCACCCCAAG
ATGGCCCCACTCTATCCACTCTCTAGACCTTTGGGAAATCTGGGTCCCTCTCCTGATTTGATCCATTCGGCCCCAACTCCAGAGTCGGGA
ATGGGAGATGAAACTAGTTTTCCACCCACTTTTGGACAAGTCCCACCCCTAGATCTGAAGCAAGCTCTACCAGCAGCGTGTCCTGGAAGC
CTGCCTGCCTGCCTGCCCGTCTGCACAGGTGTCTTGATCCAGCCCTGCGTCTTCGAGCCCCTGTGCCACCGGTCCCCACGGCCCGCCAGG
AGTCTCTTTGTACCCACTAGGCTTCCCTGATGACCATCTGTCTGTCCGTCCCTGTTTTTGCTGTACATAACTCCTGCTGCACCCTCTCCC
CGCACACCCGTCACCCATGAGAGAGAGAAACCTCTCTAGGGAAAGGCAGGGTGGCTGCACCCAGCAACTAATCCAAATGGCAAATATTTT

>99331_99331_10_WNK1-IQSEC3_WNK1_chr12_863490_ENST00000530271_IQSEC3_chr12_247432_ENST00000538872_length(amino acids)=1134AA_BP=251
MSGGAAEKQSSTPGSLFLSPPAPAPKNGSSSDSSVGEKLGAAAADAVTGRTEEYRRRRHTMDKDSRGAAATTTTTEHRFFRRSVICDSNA
TALELPGLPLSLPQPSIPAAVPQSAPPEPHREETVTATATSQVAQQPPAAAAPGEQAVAGPAPSTVPSSTSKDRPVSQPSLVGSKEEPPP
ARSGSGGGSAKEPQEERSQQQDDIEELETKAVGMSNDGRFLKFDIEIGRGSFKTVYKGLDTETTVEVAWCELQIEMLEHKYGGHLVSRRA
ACTIQTAFRQYQLSKNFEKIRNSLLESRLPRRISLRKVRSPTAESLAAEKALMEGYGLVGLPLVRSPSLPPTFAGTLTELEDSFTEQVQS
LAKSIDDALSTWSLKTMCSLRESGAYQLHQALQAAAGPPGLEAEGRAPESAGPGPGDDAAETPGLPPAHSGTLMMAFRDVTVQIANQNIS
VSSSTALSVANCLGAQTVQAPAEPAAGKAEQGETSGREAPEAPAVGREDASAEDSCAEAAASGAADGATAPKTEEEEEEEETAEVGRGAE
AEAGDLEQLSSSSTSTKSAKSGSEASASASKDALQAMILSLPRYHCENPASCKSPTLSTDTLRKRLYRIGLNLFNINPDKGIQFLISRGF
IPDTPIGVAHFLLQRKGLSRQMIGEFLGNSKKQFNRDVLDCVVDEMDFSSMELDEALRKFQAHIRVQGEAQKVERLIEAFSQRYCMCNPE
VVQQFHNPDTIFILAFAIILLNTDMYSPNIKPDRKMMLEDFIRNLRGVDDGADIPRELVVGIYERIQQKELKSNEDHVTYVTKVEKSIVG
MKTVLSVPHRRLVCCSRLFEVTDVNKLQKQAAHQREVFLFNDLLVILKLCPKKKSSSTYTFCKSVGLLGMQFQLFENEYYSHGITLVTPL
SGSEKKQVLHFCALGSDEMQKFVEDLKESIAEVTELEQIRIEWELEKQQGTKTLSFKPCGAQGDPQSKQGSPTAKREAALRERPAESTVE
VSIHNRLQTSQHNSGLGAERGAPVPPPDLQPSPPRQQTPPLPPPPPTPPGTLVQCQQIVKVIVLDKPCLARMEPLLSQALSCYTSSSSDS

--------------------------------------------------------------
>99331_99331_11_WNK1-IQSEC3_WNK1_chr12_863490_ENST00000530271_IQSEC3_chr12_247433_ENST00000326261_length(transcript)=6719nt_BP=759nt
ATGTCTGGCGGCGCCGCAGAGAAGCAGAGCAGCACTCCCGGTTCCCTGTTCCTCTCGCCGCCGGCTCCTGCCCCCAAGAATGGCTCCAGC
TCCGATTCCTCCGTGGGGGAGAAACTGGGAGCCGCGGCCGCCGACGCTGTGACCGGCAGGACCGAGGAGTACAGGCGCCGCCGCCACACT
ATGGACAAGGACAGCCGTGGGGCGGCCGCGACCACTACCACCACTGAGCACCGCTTCTTCCGCCGGAGCGTCATCTGTGACTCCAATGCC
ACTGCACTGGAGCTTCCCGGCCTTCCTCTTTCCCTGCCCCAGCCCAGCATCCCCGCGGCTGTCCCGCAGAGTGCTCCACCGGAGCCCCAC
CGGGAAGAGACCGTGACCGCCACCGCCACTTCCCAGGTAGCCCAGCAGCCTCCAGCCGCTGCCGCCCCTGGGGAACAGGCCGTCGCGGGC
CCTGCCCCCTCGACTGTCCCCAGCAGTACCAGCAAAGACCGCCCAGTGTCCCAGCCTAGCCTTGTGGGGAGCAAAGAGGAGCCGCCGCCG
GCGAGAAGTGGCAGCGGCGGCGGCAGCGCCAAGGAGCCACAGGAGGAACGGAGCCAGCAGCAGGATGATATCGAAGAGCTGGAGACCAAG
GCCGTGGGAATGTCTAACGATGGCCGCTTTCTCAAGTTTGACATCGAAATCGGCAGAGGCTCCTTTAAGACGGTCTACAAAGGTCTGGAC
ACTGAAACCACCGTGGAAGTCGCCTGGTGTGAACTGCAGATTGAAATGCTAGAACATAAGTACGGCGGTCACCTGGTGTCCCGGCGCGCC
GCTTGCACCATCCAAACCGCCTTCCGCCAATACCAGCTCAGCAAGAACTTCGAGAAAATCCGCAACTCGCTTCTGGAGAGCCGCCTGCCA
CGGCGGATCTCCCTGCGCAAGGTGCGGTCACCCACGGCCGAGAGCCTGGCGGCCGAGAAAGCGCTCATGGAGGGCTACGGCCTCGTGGGG
CTGCCGCTGGTGCGCTCGCCCTCCCTGCCGCCCACCTTCGCAGGCACCCTCACCGAGCTGGAGGACTCCTTCACCGAGCAGGTGCAATCC
CTGGCCAAGTCCATCGACGACGCGCTCAGCACGTGGAGCCTCAAGACCATGTGCTCCCTGCGGGAGAGTGGCGCTTACCAGCTCCACCAG
GCCCTGCAGGCGGCCGCGGGGCCCCCAGGCCTGGAGGCCGAGGGGCGGGCGCCGGAGAGCGCGGGCCCCGGGCCCGGGGATGACGCCGCG
GAGACCCCCGGCCTGCCCCCGGCCCACAGCGGGACCCTCATGATGGCTTTCCGGGACGTCACGGTGCAGATCGCCAACCAGAACATATCC
GTCTCCTCCTCCACGGCTCTGTCGGTGGCCAACTGCCTGGGCGCTCAGACGGTCCAGGCCCCCGCAGAGCCCGCGGCGGGCAAGGCCGAG
CAGGGCGAGACCTCTGGGCGGGAGGCCCCGGAAGCCCCCGCCGTGGGCCGGGAGGACGCGTCAGCCGAGGACTCATGCGCAGAGGCTGCG
GCTAGTGGGGCGGCGGATGGGGCCACAGCCCCCAAAACAGAGGAGGAAGAGGAGGAGGAGGAGACGGCGGAGGTGGGGAGAGGGGCCGAG
GCCGAGGCAGGCGACTTGGAGCAGCTGAGCAGCAGCAGCACGTCCACCAAGTCCGCCAAGTCAGGCTCGGAGGCGTCGGCCTCCGCCTCC
AAGGACGCCCTGCAGGCCATGATCCTGAGCCTGCCGCGCTACCACTGCGAGAACCCAGCCAGCTGCAAGTCGCCCACGCTCTCCACCGAC
ACCCTGCGCAAGCGGCTCTACCGCATCGGCCTCAACCTCTTCAACATAAACCCCGACAAGGGCATCCAGTTCCTGATCTCACGCGGCTTC
ATCCCGGACACCCCCATCGGTGTGGCCCATTTCCTCCTCCAGCGAAAGGGCCTCAGCCGCCAGATGATTGGAGAGTTCCTGGGCAACAGC
AAGAAGCAGTTCAACCGCGACGTGCTGGACTGCGTGGTGGACGAGATGGACTTCTCCAGCATGGAGCTGGACGAGGCCCTGCGCAAGTTC
CAGGCACACATCCGTGTGCAGGGGGAGGCTCAGAAGGTGGAGCGGCTCATTGAGGCCTTCAGCCAGCGCTACTGCATGTGCAACCCCGAA
GTGGTTCAGCAGTTCCACAACCCCGACACCATCTTCATCCTCGCCTTCGCCATCATCCTCCTCAACACCGACATGTACAGCCCCAACATC
AAGCCTGACCGGAAGATGATGCTGGAGGACTTCATCCGAAACCTTCGAGGTGTGGACGATGGCGCTGACATCCCCAGGGAGCTGGTGGTA
GGCATCTATGAGAGGATACAGCAGAAGGAGCTCAAGTCCAATGAGGACCACGTCACGTACGTCACCAAGGTGGAGAAGTCCATTGTGGGC
ATGAAGACAGTGCTGTCCGTGCCCCACCGCCGCCTGGTGTGCTGCAGCCGGCTCTTCGAGGTGACGGATGTGAACAAGCTGCAGAAGCAG
GCAGCGCATCAGAGGGAGGTGTTCCTCTTCAATGACCTGCTGGTGATTCTCAAACTTTGCCCGAAGAAGAAGAGCTCCTCCACGTACACC
TTTTGCAAGTCAGTTGGCCTGCTGGGCATGCAGTTCCAGCTCTTTGAGAACGAGTATTACTCTCATGGCATCACACTGGTGACCCCGCTC
TCGGGCTCCGAGAAGAAGCAGGTGCTGCATTTCTGTGCCCTGGGCTCGGACGAGATGCAGAAGTTCGTGGAGGACCTGAAGGAGTCCATT
GCTGAGGTGACGGAGCTGGAGCAGATCCGAATAGAGTGGGAGCTGGAGAAGCAGCAGGGAACAAAGACACTCTCCTTCAAGCCCTGCGGA
GCCCAGGGGGACCCACAGTCAAAGCAAGGATCGCCGACAGCCAAAAGGGAAGCCGCGCTCAGGGAGAGGCCGGCGGAGAGCACGGTGGAG
GTGTCAATTCACAACAGGCTTCAAACGTCCCAGCACAACTCCGGGCTGGGGGCCGAGAGGGGAGCGCCGGTGCCGCCGCCAGACCTGCAG
CCTAGCCCCCCGAGACAGCAGACCCCACCACTGCCGCCGCCGCCACCCACGCCCCCGGGCACCCTGGTGCAGTGCCAGCAAATTGTCAAG
GTCATTGTCCTGGACAAGCCCTGCCTGGCCCGCATGGAGCCCCTGCTGAGCCAGGCTCTCTCCTGCTACACCTCGTCGTCCTCTGACTCC
TGCGGCTCCACACCCCTGGGCGGTCCCGGCTCTCCGGTCAAGGTCACCCACCAGCCTCCGCTGCCCCCGCCCCCACCCCCCTACAACCAC
CCTCACCAGTTCTGTCCCCCAGGCTCCCTGCTGCACGGGCACCGCTACTCCAGTGGCTCAAGGAGCCTGGTGTAGACTCTGCCCCACCAC
CCTGCTGTCCTGGGAGGGCTGGCCACTGGGGGGCCTGGGCTGCCCCTCCACTGCTCCCCATACCCTGGCACGATGCGTTCCTGGTCACTG
ATCACCATCATTTTGGGAAGAGAATCCCAATCCCTGGCACCTGGGTTTGCCTCATCCAACCATCCTTCCCTTTCTCAGCTGCACCCCCTC
TGCAGATCTGAAGACACACCTCACTCTCCCAGGGCCCTACACAGCCAGACCCGGCGAGGCCTCCTCTTCCCCTGGCCACCACTTTCCCCC
ATTGGACCATGGACTGAAGAAAACGAGCTGAGGGTCTAACGAGCTTGCAGGCTTTGAGTCTGTTAGTGCCCGGGGCCTCGGGCCTTGGGC
AGCAGCATGAGGCTGGGCCGGCCGGCAGTGGAGCACTAGACAGAGTGGCTGGCTCGCAGCCCAGAACTAGTGCCTCTGTAGCTGCACTGA
GGGGAGGAGGGTTGGTCCCACCCCTGGAGGGACAGGTGGGAGGAGTGAGGAGGGGGCTTTTTCTGCCACCCCCGCCCCCAAGCCTGAAAC
TCTCAGGAGTCTACTTCTTGGTCCCCAGGGACATTGGCTGTCCTGACCATGTCCTTCCCCCTCCTCCCAGGGCCTCTGCTTCCTCAGGAG
CTGCCCAGACTCCAGAAAAGCCTGGAAAAAGGGAGGCGGGAAGGGGAGCACTTTCGGCTTTCTATAGGTCAGTCCAGCAGGGCCACGGGA
TCGCGAGGTCATGTATCTGCAAAATGCACCTTTTTAAAGAGTGTCTTAGTTCCCCAGCCCCAGCTAATACCCGGCCAATGCCGTGTACGC
ACCGGCATGTGCACGCAAACACGCATGAGAACCAGGCCATTCCTTCCGCTGTGGAAGCAGAACTGGAGACGGGGCAGGAATGTGCCCAGC
AGAGATGGGGCTCAGCCCGAGGCAGGGCTCCCTCCTGCATGAGGCTCGGCCCGAGGCAGGGCTCCCTCCTGCATGAGTCTGTGGCCTCCA
GGAGGGACTTGGGTGCAGATGTAAGCAAGAAAAACCGGGGCTCCAGAGGCATGTGCATTTCCCCTGCGCCCCTCAGCCTTTAAATATTCC
CTCCTCCTAGAAGGTTCTAGACCCCCCCCTTCCAGCAGGGGTGCCCAAGAGTCCCTGGACCCTCAAAATTGCAAAGGAGACCCAAGCGGG
GCTCGCTGACCTCCCAGGGCCCAGCAAGATGGGATAGCCAGCCTTAGGTGGCCCCACGAGCCCAAGCCTGGGGAAGGGCCCCTCCCCAGC
CAGACGAGAGGCAGCCACCCCAGAGACCACAGGAGCCGTACCATGGCCTGCGCAGTCAGGCCCTATCAGGATGTGTCTGTCCCAAGCCTG
GCCAGGCTCCAGTCCTGTGCCAGTAGCTCACTGCTGTCCTATGTGCAGGTCCCCCAACACTTGGAGCCTGTGGTTAAGGCCTCCTGGGAG
AGGCAGTGAGCATGAGTCAAAGGTGACATGGACTTGAATCTCCCCACCCCGCCCCGCCTGCAGTAGCCGGGCCAGGTAGGAGGCAAGGAT
CATTCCCTGCTCCCAGAGGTTCCAGATGACCTAGTTTCGTTTTGTGTGTGTGTGTGTGTGGTCACCCAGACGTCACTGTGATATCACCTA
GTGAATCTATTTCTGGCCCTGTCTTCGTCGGCCCAGTTTCTGTAACTTGCAGCCAATTTGCCCTCTCCCCTGTGGCTGCCAGCCCATCTG
CCCCTCTGTGTCCTTGCTGCCCTGGCCCTCCTCTGTTTTCTGTAACAGATGCTCCAGTCATTGCCTTTCAGAGTGGAGCAGATGACAGAT
GGGGTGCACGCATTCAGACACCTCTGATGCCCTTAGCCAGGGCAGGGATCGTCCTTAAAGTGAAGGCCTGGACAGGAGGAGTCAGGGACT
TGGGAGGAGGTGGAGCTGTGGGGATGGGAGTGGAGGAATCAAAATGAGGGAAGCTGAAAATAGAATGAAAACGATGACTAAGAGGCAGGG
AGTGCGAGGTATGGGGGAATAGGAACTATGAGCTAAATATACTTATGGGGTGGGGGCCGTGGGGGCCAGGGACACTCTCCCAGACAGCCC
TGACCCGCCAGGCAGGACCCCGTCCCCTGCTCACACAGCTCTTCAAACTTACCAAGGACAGGCAGGACCCCGTCCCCTGCTCACACAGCT
CTTCAAGCTTACCAAGTCCCCTGTTGAGGGCACAGCAACCCCAGGCCCTCCCTCCCACCTCAGCTGAAGCCCCAATCTTCCAAATCGGAA
CCAGCAAGTCTTAGGGCTGGCACGCATCTGGGCCTCTAGCTGAGAACCCGGACTCTCAGGCACCTCAGTGCCCCTGCCCCAGGGCAGAGG
CCCACCCCGTGGGTTGGTGCAGTGGCTGCCCTGGGCTCCACGGGCAGCACAGGGAGTCTGTCCAGGAAGCAGCCCAGCCGGGGTCAGTAT
TCCGTGGAGCCAGTCCTGAGCTGGGAGGGGCATTTAACACCCCTGAGGGCCTGGGGCAGGACACAGCTGGCCCTCCTCATTGTCAGGGGA
AGCAAGTGCCCAACATCTGTAACCTCCCTTCCCTGCTCAGTCCCCAGGCCAAGGTTGGGACCCCTCTCCATCCCTGTCCCCAGAGCCTAG
ACCTCAGGGACCTAGGAAAAGCCTCCTGCTCCCTCCCCACGGCAGCAGACAGGGCAGGGCCTCCAGCCCCCAGAGGGCCGGTGGGGGGTG
CTCTCGGGCCTTCCTGCTCTCCTAAGGTTGCGGGGACAGTAGAGTGCTGAGCCCCAGACCCAGTCACCCCAAGATGGCCCCACTCTATCC
ACTCTCTAGACCTTTGGGAAATCTGGGTCCCTCTCCTGATTTGATCCATTCGGCCCCAACTCCAGAGTCGGGAATGGGAGATGAAACTAG
TTTTCCACCCACTTTTGGACAAGTCCCACCCCTAGATCTGAAGCAAGCTCTACCAGCAGCGTGTCCTGGAAGCCTGCCTGCCTGCCTGCC
CGTCTGCACAGGTGTCTTGATCCAGCCCTGCGTCTTCGAGCCCCTGTGCCACCGGTCCCCACGGCCCGCCAGGAGTCTCTTTGTACCCAC
TAGGCTTCCCTGATGACCATCTGTCTGTCCGTCCCTGTTTTTGCTGTACATAACTCCTGCTGCACCCTCTCCCCGCACACCCGTCACCCA
TGAGAGAGAGAAACCTCTCTAGGGAAAGGCAGGGTGGCTGCACCCAGCAACTAATCCAAATGGCAAATATTTTGTAACAAAATAGCCCAG

>99331_99331_11_WNK1-IQSEC3_WNK1_chr12_863490_ENST00000530271_IQSEC3_chr12_247433_ENST00000326261_length(amino acids)=1134AA_BP=251
MSGGAAEKQSSTPGSLFLSPPAPAPKNGSSSDSSVGEKLGAAAADAVTGRTEEYRRRRHTMDKDSRGAAATTTTTEHRFFRRSVICDSNA
TALELPGLPLSLPQPSIPAAVPQSAPPEPHREETVTATATSQVAQQPPAAAAPGEQAVAGPAPSTVPSSTSKDRPVSQPSLVGSKEEPPP
ARSGSGGGSAKEPQEERSQQQDDIEELETKAVGMSNDGRFLKFDIEIGRGSFKTVYKGLDTETTVEVAWCELQIEMLEHKYGGHLVSRRA
ACTIQTAFRQYQLSKNFEKIRNSLLESRLPRRISLRKVRSPTAESLAAEKALMEGYGLVGLPLVRSPSLPPTFAGTLTELEDSFTEQVQS
LAKSIDDALSTWSLKTMCSLRESGAYQLHQALQAAAGPPGLEAEGRAPESAGPGPGDDAAETPGLPPAHSGTLMMAFRDVTVQIANQNIS
VSSSTALSVANCLGAQTVQAPAEPAAGKAEQGETSGREAPEAPAVGREDASAEDSCAEAAASGAADGATAPKTEEEEEEEETAEVGRGAE
AEAGDLEQLSSSSTSTKSAKSGSEASASASKDALQAMILSLPRYHCENPASCKSPTLSTDTLRKRLYRIGLNLFNINPDKGIQFLISRGF
IPDTPIGVAHFLLQRKGLSRQMIGEFLGNSKKQFNRDVLDCVVDEMDFSSMELDEALRKFQAHIRVQGEAQKVERLIEAFSQRYCMCNPE
VVQQFHNPDTIFILAFAIILLNTDMYSPNIKPDRKMMLEDFIRNLRGVDDGADIPRELVVGIYERIQQKELKSNEDHVTYVTKVEKSIVG
MKTVLSVPHRRLVCCSRLFEVTDVNKLQKQAAHQREVFLFNDLLVILKLCPKKKSSSTYTFCKSVGLLGMQFQLFENEYYSHGITLVTPL
SGSEKKQVLHFCALGSDEMQKFVEDLKESIAEVTELEQIRIEWELEKQQGTKTLSFKPCGAQGDPQSKQGSPTAKREAALRERPAESTVE
VSIHNRLQTSQHNSGLGAERGAPVPPPDLQPSPPRQQTPPLPPPPPTPPGTLVQCQQIVKVIVLDKPCLARMEPLLSQALSCYTSSSSDS

--------------------------------------------------------------
>99331_99331_12_WNK1-IQSEC3_WNK1_chr12_863490_ENST00000530271_IQSEC3_chr12_247433_ENST00000538872_length(transcript)=6832nt_BP=759nt
ATGTCTGGCGGCGCCGCAGAGAAGCAGAGCAGCACTCCCGGTTCCCTGTTCCTCTCGCCGCCGGCTCCTGCCCCCAAGAATGGCTCCAGC
TCCGATTCCTCCGTGGGGGAGAAACTGGGAGCCGCGGCCGCCGACGCTGTGACCGGCAGGACCGAGGAGTACAGGCGCCGCCGCCACACT
ATGGACAAGGACAGCCGTGGGGCGGCCGCGACCACTACCACCACTGAGCACCGCTTCTTCCGCCGGAGCGTCATCTGTGACTCCAATGCC
ACTGCACTGGAGCTTCCCGGCCTTCCTCTTTCCCTGCCCCAGCCCAGCATCCCCGCGGCTGTCCCGCAGAGTGCTCCACCGGAGCCCCAC
CGGGAAGAGACCGTGACCGCCACCGCCACTTCCCAGGTAGCCCAGCAGCCTCCAGCCGCTGCCGCCCCTGGGGAACAGGCCGTCGCGGGC
CCTGCCCCCTCGACTGTCCCCAGCAGTACCAGCAAAGACCGCCCAGTGTCCCAGCCTAGCCTTGTGGGGAGCAAAGAGGAGCCGCCGCCG
GCGAGAAGTGGCAGCGGCGGCGGCAGCGCCAAGGAGCCACAGGAGGAACGGAGCCAGCAGCAGGATGATATCGAAGAGCTGGAGACCAAG
GCCGTGGGAATGTCTAACGATGGCCGCTTTCTCAAGTTTGACATCGAAATCGGCAGAGGCTCCTTTAAGACGGTCTACAAAGGTCTGGAC
ACTGAAACCACCGTGGAAGTCGCCTGGTGTGAACTGCAGATTGAAATGCTAGAACATAAGTACGGCGGTCACCTGGTGTCCCGGCGCGCC
GCTTGCACCATCCAAACCGCCTTCCGCCAATACCAGCTCAGCAAGAACTTCGAGAAAATCCGCAACTCGCTTCTGGAGAGCCGCCTGCCA
CGGCGGATCTCCCTGCGCAAGGTGCGGTCACCCACGGCCGAGAGCCTGGCGGCCGAGAAAGCGCTCATGGAGGGCTACGGCCTCGTGGGG
CTGCCGCTGGTGCGCTCGCCCTCCCTGCCGCCCACCTTCGCAGGCACCCTCACCGAGCTGGAGGACTCCTTCACCGAGCAGGTGCAATCC
CTGGCCAAGTCCATCGACGACGCGCTCAGCACGTGGAGCCTCAAGACCATGTGCTCCCTGCGGGAGAGTGGCGCTTACCAGCTCCACCAG
GCCCTGCAGGCGGCCGCGGGGCCCCCAGGCCTGGAGGCCGAGGGGCGGGCGCCGGAGAGCGCGGGCCCCGGGCCCGGGGATGACGCCGCG
GAGACCCCCGGCCTGCCCCCGGCCCACAGCGGGACCCTCATGATGGCTTTCCGGGACGTCACGGTGCAGATCGCCAACCAGAACATATCC
GTCTCCTCCTCCACGGCTCTGTCGGTGGCCAACTGCCTGGGCGCTCAGACGGTCCAGGCCCCCGCAGAGCCCGCGGCGGGCAAGGCCGAG
CAGGGCGAGACCTCTGGGCGGGAGGCCCCGGAAGCCCCCGCCGTGGGCCGGGAGGACGCGTCAGCCGAGGACTCATGCGCAGAGGCTGCG
GCTAGTGGGGCGGCGGATGGGGCCACAGCCCCCAAAACAGAGGAGGAAGAGGAGGAGGAGGAGACGGCGGAGGTGGGGAGAGGGGCCGAG
GCCGAGGCAGGCGACTTGGAGCAGCTGAGCAGCAGCAGCACGTCCACCAAGTCCGCCAAGTCAGGCTCGGAGGCGTCGGCCTCCGCCTCC
AAGGACGCCCTGCAGGCCATGATCCTGAGCCTGCCGCGCTACCACTGCGAGAACCCAGCCAGCTGCAAGTCGCCCACGCTCTCCACCGAC
ACCCTGCGCAAGCGGCTCTACCGCATCGGCCTCAACCTCTTCAACATAAACCCCGACAAGGGCATCCAGTTCCTGATCTCACGCGGCTTC
ATCCCGGACACCCCCATCGGTGTGGCCCATTTCCTCCTCCAGCGAAAGGGCCTCAGCCGCCAGATGATTGGAGAGTTCCTGGGCAACAGC
AAGAAGCAGTTCAACCGCGACGTGCTGGACTGCGTGGTGGACGAGATGGACTTCTCCAGCATGGAGCTGGACGAGGCCCTGCGCAAGTTC
CAGGCACACATCCGTGTGCAGGGGGAGGCTCAGAAGGTGGAGCGGCTCATTGAGGCCTTCAGCCAGCGCTACTGCATGTGCAACCCCGAA
GTGGTTCAGCAGTTCCACAACCCCGACACCATCTTCATCCTCGCCTTCGCCATCATCCTCCTCAACACCGACATGTACAGCCCCAACATC
AAGCCTGACCGGAAGATGATGCTGGAGGACTTCATCCGAAACCTTCGAGGTGTGGACGATGGCGCTGACATCCCCAGGGAGCTGGTGGTA
GGCATCTATGAGAGGATACAGCAGAAGGAGCTCAAGTCCAATGAGGACCACGTCACGTACGTCACCAAGGTGGAGAAGTCCATTGTGGGC
ATGAAGACAGTGCTGTCCGTGCCCCACCGCCGCCTGGTGTGCTGCAGCCGGCTCTTCGAGGTGACGGATGTGAACAAGCTGCAGAAGCAG
GCAGCGCATCAGAGGGAGGTGTTCCTCTTCAATGACCTGCTGGTGATTCTCAAACTTTGCCCGAAGAAGAAGAGCTCCTCCACGTACACC
TTTTGCAAGTCAGTTGGCCTGCTGGGCATGCAGTTCCAGCTCTTTGAGAACGAGTATTACTCTCATGGCATCACACTGGTGACCCCGCTC
TCGGGCTCCGAGAAGAAGCAGGTGCTGCATTTCTGTGCCCTGGGCTCGGACGAGATGCAGAAGTTCGTGGAGGACCTGAAGGAGTCCATT
GCTGAGGTGACGGAGCTGGAGCAGATCCGAATAGAGTGGGAGCTGGAGAAGCAGCAGGGAACAAAGACACTCTCCTTCAAGCCCTGCGGA
GCCCAGGGGGACCCACAGTCAAAGCAAGGATCGCCGACAGCCAAAAGGGAAGCCGCGCTCAGGGAGAGGCCGGCGGAGAGCACGGTGGAG
GTGTCAATTCACAACAGGCTTCAAACGTCCCAGCACAACTCCGGGCTGGGGGCCGAGAGGGGAGCGCCGGTGCCGCCGCCAGACCTGCAG
CCTAGCCCCCCGAGACAGCAGACCCCACCACTGCCGCCGCCGCCACCCACGCCCCCGGGCACCCTGGTGCAGTGCCAGCAAATTGTCAAG
GTCATTGTCCTGGACAAGCCCTGCCTGGCCCGCATGGAGCCCCTGCTGAGCCAGGCTCTCTCCTGCTACACCTCGTCGTCCTCTGACTCC
TGCGGCTCCACACCCCTGGGCGGTCCCGGCTCTCCGGTCAAGGTCACCCACCAGCCTCCGCTGCCCCCGCCCCCACCCCCCTACAACCAC
CCTCACCAGTTCTGTCCCCCAGGCTCCCTGCTGCACGGGCACCGCTACTCCAGTGGCTCAAGGAGCCTGGTGTAGACTCTGCCCCACCAC
CCTGCTGTCCTGGGAGGGCTGGCCACTGGGGGGCCTGGGCTGCCCCTCCACTGCTCCCCATACCCTGGCACGATGCGTTCCTGGTCACTG
ATCACCATCATTTTGGGAAGAGAATCCCAATCCCTGGCACCTGGGTTTGCCTCATCCAACCATCCTTCCCTTTCTCAGCTGCACCCCCTC
TGCAGATCTGAAGACACACCTCACTCTCCCAGGGCCCTACACAGCCAGACCCGGCGAGGCCTCCTCTTCCCCTGGCCACCACTTTCCCCC
ATTGGACCATGGACTGAAGAAAACGAGCTGAGGGTCTAACGAGCTTGCAGGCTTTGAGTCTGTTAGTGCCCGGGGCCTCGGGCCTTGGGC
AGCAGCATGAGGCTGGGCCGGCCGGCAGTGGAGCACTAGACAGAGTGGCTGGCTCGCAGCCCAGAACTAGTGCCTCTGTAGCTGCACTGA
GGGGAGGAGGGTTGGTCCCACCCCTGGAGGGACAGGTGGGAGGAGTGAGGAGGGGGCTTTTTCTGCCACCCCCGCCCCCAAGCCTGAAAC
TCTCAGGAGTCTACTTCTTGGTCCCCAGGGACATTGGCTGTCCTGACCATGTCCTTCCCCCTCCTCCCAGGGCCTCTGCTTCCTCAGGAG
CTGCCCAGACTCCAGAAAAGCCTGGAAAAAGGGAGGCGGGAAGGGGAGCACTTTCGGCTTTCTATAGGTCAGTCCAGCAGGGCCACGGGA
TCGCGAGGTCATGTATCTGCAAAATGCACCTTTTTAAAGAGTGTCTTAGTTCCCCAGCCCCAGCTAATACCCGGCCAATGCCGTGTACGC
ACCGGCATGTGCACGCAAACACGCATGAGAACCAGGCCATTCCTTCCGCTGTGGAAGCAGAACTGGAGACGGGGCAGGAATGTGCCCAGC
AGAGATGGGGCTCAGCCCGAGGCAGGGCTCCCTCCTGCATGAGGCTCGGCCCGAGGCAGGGCTCCCTCCTGCATGAGTCTGTGGCCTCCA
GGAGGGACTTGGGTGCAGATGTAAGCAAGAAAAACCGGGGCTCCAGAGGCATGTGCATTTCCCCTGCGCCCCTCAGCCTTTAAATATTCC
CTCCTCCTAGAAGGTTCTAGACCCCCCCCTTCCAGCAGGGGTGCCCAAGAGTCCCTGGACCCTCAAAATTGCAAAGGAGACCCAAGCGGG
GCTCGCTGACCTCCCAGGGCCCAGCAAGATGGGATAGCCAGCCTTAGGTGGCCCCACGAGCCCAAGCCTGGGGAAGGGCCCCTCCCCAGC
CAGACGAGAGGCAGCCACCCCAGAGACCACAGGAGCCGTACCATGGCCTGCGCAGTCAGGCCCTATCAGGATGTGTCTGTCCCAAGCCTG
GCCAGGCTCCAGTCCTGTGCCAGTAGCTCACTGCTGTCCTATGTGCAGGTCCCCCAACACTTGGAGCCTGTGGTTAAGGCCTCCTGGGAG
AGGCAGTGAGCATGAGTCAAAGGTGACATGGACTTGAATCTCCCCACCCCGCCCCGCCTGCAGTAGCCGGGCCAGGTAGGAGGCAAGGAT
CATTCCCTGCTCCCAGAGGTTCCAGATGACCTAGTTTCGTTTTGTGTGTGTGTGTGTGTGGTCACCCAGACGTCACTGTGATATCACCTA
GTGAATCTATTTCTGGCCCTGTCTTCGTCGGCCCAGTTTCTGTAACTTGCAGCCAATTTGCCCTCTCCCCTGTGGCTGCCAGCCCATCTG
CCCCTCTGTGTCCTTGCTGCCCTGGCCCTCCTCTGTTTTCTGTAACAGATGCTCCAGTCATTGCCTTTCAGAGTGGAGCAGATGACAGAT
GGGGTGCACGCATTCAGACACCTCTGATGCCCTTAGCCAGGGCAGGGATCGTCCTTAAAGTGAAGGCCTGGACAGGAGGAGTCAGGGACT
TGGGAGGAGGTGGAGCTGTGGGGATGGGAGTGGAGGAATCAAAATGAGGGAAGCTGAAAATAGAATGAAAACGATGACTAAGAGGCAGGG
AGTGCGAGGTATGGGGGAATAGGAACTATGAGCTAAATATACTTATGGGGTGGGGGCCGTGGGGGCCAGGGACACTCTCCCAGACAGCCC
TGACCCGCCAGGCAGGACCCCGTCCCCTGCTCACACAGCTCTTCAAACTTACCAAGGACAGGCAGGACCCCGTCCCCTGCTCACACAGCT
CTTCAAGCTTACCAAGGACAGGCAGAACCCCGTCCCCTGCTCACACAGCTCTTCAAGCTTACCAAGGACAGGCAGGACCCCGTCCCCTGC
TCACACAGCTCTTCAAACTTACCAAGTGCCCTCTCCCCTGTTGAGGGCACAGCAACCCCAGGCCCTCCCTCCCACCTCAGCTGAAGCCCC
AATCTTCCAAATCGGAACCAGCAAGTCTTAGGGCTGGCACGCATCTGGGCCTCTAGCTGAGAACCCGGACTCTCAGGCACCTCAGTGCCC
CTGCCCCAGGGCAGAGGCCCACCCCGTGGGTTGGTGCAGTGGCTGCCCTGGGCTCCACGGGCAGCACAGGGAGTCTGTCCAGGAAGCAGC
CCAGCCGGGGTCAGTATTCCGTGGAGCCAGTCCTGAGCTGGGAGGGGCATTTAACACCCCTGAGGGCCTGGGGCAGGACACAGCTGGCCC
TCCTCATTGTCAGGGGAAGCAAGTGCCCAACATCTGTAACCTCCCTTCCCTGCTCAGTCCCCAGGCCAAGGTTGGGACCCCTCTCCATCC
CTGTCCCCAGAGCCTAGACCTCAGGGACCTAGGAAAAGCCTCCTGCTCCCTCCCCACGGCAGCAGACAGGGCAGGGCCTCCAGCCCCCAG
AGGGCCGGTGGGGGGTGCTCTCGGGCCTTCCTGCTCTCCTAAGGTTGCGGGGACAGTAGAGTGCTGAGCCCCAGACCCAGTCACCCCAAG
ATGGCCCCACTCTATCCACTCTCTAGACCTTTGGGAAATCTGGGTCCCTCTCCTGATTTGATCCATTCGGCCCCAACTCCAGAGTCGGGA
ATGGGAGATGAAACTAGTTTTCCACCCACTTTTGGACAAGTCCCACCCCTAGATCTGAAGCAAGCTCTACCAGCAGCGTGTCCTGGAAGC
CTGCCTGCCTGCCTGCCCGTCTGCACAGGTGTCTTGATCCAGCCCTGCGTCTTCGAGCCCCTGTGCCACCGGTCCCCACGGCCCGCCAGG
AGTCTCTTTGTACCCACTAGGCTTCCCTGATGACCATCTGTCTGTCCGTCCCTGTTTTTGCTGTACATAACTCCTGCTGCACCCTCTCCC
CGCACACCCGTCACCCATGAGAGAGAGAAACCTCTCTAGGGAAAGGCAGGGTGGCTGCACCCAGCAACTAATCCAAATGGCAAATATTTT

>99331_99331_12_WNK1-IQSEC3_WNK1_chr12_863490_ENST00000530271_IQSEC3_chr12_247433_ENST00000538872_length(amino acids)=1134AA_BP=251
MSGGAAEKQSSTPGSLFLSPPAPAPKNGSSSDSSVGEKLGAAAADAVTGRTEEYRRRRHTMDKDSRGAAATTTTTEHRFFRRSVICDSNA
TALELPGLPLSLPQPSIPAAVPQSAPPEPHREETVTATATSQVAQQPPAAAAPGEQAVAGPAPSTVPSSTSKDRPVSQPSLVGSKEEPPP
ARSGSGGGSAKEPQEERSQQQDDIEELETKAVGMSNDGRFLKFDIEIGRGSFKTVYKGLDTETTVEVAWCELQIEMLEHKYGGHLVSRRA
ACTIQTAFRQYQLSKNFEKIRNSLLESRLPRRISLRKVRSPTAESLAAEKALMEGYGLVGLPLVRSPSLPPTFAGTLTELEDSFTEQVQS
LAKSIDDALSTWSLKTMCSLRESGAYQLHQALQAAAGPPGLEAEGRAPESAGPGPGDDAAETPGLPPAHSGTLMMAFRDVTVQIANQNIS
VSSSTALSVANCLGAQTVQAPAEPAAGKAEQGETSGREAPEAPAVGREDASAEDSCAEAAASGAADGATAPKTEEEEEEEETAEVGRGAE
AEAGDLEQLSSSSTSTKSAKSGSEASASASKDALQAMILSLPRYHCENPASCKSPTLSTDTLRKRLYRIGLNLFNINPDKGIQFLISRGF
IPDTPIGVAHFLLQRKGLSRQMIGEFLGNSKKQFNRDVLDCVVDEMDFSSMELDEALRKFQAHIRVQGEAQKVERLIEAFSQRYCMCNPE
VVQQFHNPDTIFILAFAIILLNTDMYSPNIKPDRKMMLEDFIRNLRGVDDGADIPRELVVGIYERIQQKELKSNEDHVTYVTKVEKSIVG
MKTVLSVPHRRLVCCSRLFEVTDVNKLQKQAAHQREVFLFNDLLVILKLCPKKKSSSTYTFCKSVGLLGMQFQLFENEYYSHGITLVTPL
SGSEKKQVLHFCALGSDEMQKFVEDLKESIAEVTELEQIRIEWELEKQQGTKTLSFKPCGAQGDPQSKQGSPTAKREAALRERPAESTVE
VSIHNRLQTSQHNSGLGAERGAPVPPPDLQPSPPRQQTPPLPPPPPTPPGTLVQCQQIVKVIVLDKPCLARMEPLLSQALSCYTSSSSDS

--------------------------------------------------------------
>99331_99331_13_WNK1-IQSEC3_WNK1_chr12_863490_ENST00000535572_IQSEC3_chr12_247432_ENST00000326261_length(transcript)=7692nt_BP=1732nt
ATTTAGCGCGGAGAGTTTCCCGGGTGGACGCGGCTCCTCTCTCGGCCACTCCGCACCCCCATCTTCGGTGACAGAAGGCGCCTGGTGGGG
GTGGCTGCTCTTTTCTCTCCCTGTTCCCCCTCACCCAGTCCTCTAGGTCTCCTCTCCTCTTGCCTCAGAGAAGCAGCGGAGCTCGGGCCC
CGCGGTGAGCGGCCCTCCCCTCCCCGCCGTTCCCTCCTCCGTCAGCCCCCGGCACCGGCCCGGGAGGAGACGGGTTTGCCAGGCCTGGGG
CGGGCGGGGAGGCCTCGGGGAAGGGGGGGCCCGCTCCTCAGGCGCCGAGGCTCCGAGGCTCCGGCCCTTCGCCTCTGGGCGATGGGCGAC
CTGTGAGGCCGGTCCCCATCGCTGGGGGCGCGTGTGGGAGGAGGCGGCCGCCCGAGTGACCGGGAGCCGGGCCGCGGCCTTCCCTCGCCC
GCCTCGGCCCCTCCCACTCCTCTGCCCCGGGGCCGCCACCGCCCGGGCGTCGGACCTGGTCCCGTGCTCGCGGTGCCGCCGCCCTCTGGG
CCTAGCCCGCCCAGCTCGGCGAGCGGCGGCAGTGGGAGCCGCGTCCGCCGCATCCGCCTCGACTCGGTGCCGGCCCCTGGCCCTCCCCTC
ATGACTGCGGCGCCTCTGCTGCCACCGCCCGCCCGGCCGCCGCTCGCCGCAGGATGGATGCGGACCGTGCGGCGCTAACCCCCGTGGCTC
AGCTCCCGAATCGCCCGCCTTCGAGCCCTCCTCGTGAGCCGCAGCAGCCTCGGTGCCAGCCCCCGCCGCAGCTGGGCCCAGCGGTCCGCC
TGTCCCTCGTTGCGGCTTGTCGGTGCTGAGTGAGGCGTCGTCCGGGTCGGCGCGAACCCGCCCGGCCGCGGTTCCCTGCAGACCTCTGCG
CGGGCGGCTCGGCCCTTCACGCCCTTTTCGTTCACGAATCCGAGCCCGCTCGCCTCTCTCCAGCGAACCGACCATGTCTGGCGGCGCCGC
AGAGAAGCAGAGCAGCACTCCCGGTTCCCTGTTCCTCTCGCCGCCGGCTCCTGCCCCCAAGAATGGCTCCAGCTCCGATTCCTCCGTGGG
GGAGAAACTGGGAGCCGCGGCCGCCGACGCTGTGACCGGCAGGACCGAGGAGTACAGGCGCCGCCGCCACACTATGGACAAGGACAGCCG
TGGGGCGGCCGCGACCACTACCACCACTGAGCACCGCTTCTTCCGCCGGAGCGTCATCTGTGACTCCAATGCCACTGCACTGGAGCTTCC
CGGCCTTCCTCTTTCCCTGCCCCAGCCCAGCATCCCCGCGGCTGTCCCGCAGAGTGCTCCACCGGAGCCCCACCGGGAAGAGACCGTGAC
CGCCACCGCCACTTCCCAGGTAGCCCAGCAGCCTCCAGCCGCTGCCGCCCCTGGGGAACAGGCCGTCGCGGGCCCTGCCCCCTCGACTGT
CCCCAGCAGTACCAGCAAAGACCGCCCAGTGTCCCAGCCTAGCCTTGTGGGGAGCAAAGAGGAGCCGCCGCCGGCGAGAAGTGGCAGCGG
CGGCGGCAGCGCCAAGGAGCCACAGGAGGAACGGAGCCAGCAGCAGGATGATATCGAAGAGCTGGAGACCAAGGCCGTGGGAATGTCTAA
CGATGGCCGCTTTCTCAAGTTTGACATCGAAATCGGCAGAGGCTCCTTTAAGACGGTCTACAAAGGTCTGGACACTGAAACCACCGTGGA
AGTCGCCTGGTGTGAACTGCAGATTGAAATGCTAGAACATAAGTACGGCGGTCACCTGGTGTCCCGGCGCGCCGCTTGCACCATCCAAAC
CGCCTTCCGCCAATACCAGCTCAGCAAGAACTTCGAGAAAATCCGCAACTCGCTTCTGGAGAGCCGCCTGCCACGGCGGATCTCCCTGCG
CAAGGTGCGGTCACCCACGGCCGAGAGCCTGGCGGCCGAGAAAGCGCTCATGGAGGGCTACGGCCTCGTGGGGCTGCCGCTGGTGCGCTC
GCCCTCCCTGCCGCCCACCTTCGCAGGCACCCTCACCGAGCTGGAGGACTCCTTCACCGAGCAGGTGCAATCCCTGGCCAAGTCCATCGA
CGACGCGCTCAGCACGTGGAGCCTCAAGACCATGTGCTCCCTGCGGGAGAGTGGCGCTTACCAGCTCCACCAGGCCCTGCAGGCGGCCGC
GGGGCCCCCAGGCCTGGAGGCCGAGGGGCGGGCGCCGGAGAGCGCGGGCCCCGGGCCCGGGGATGACGCCGCGGAGACCCCCGGCCTGCC
CCCGGCCCACAGCGGGACCCTCATGATGGCTTTCCGGGACGTCACGGTGCAGATCGCCAACCAGAACATATCCGTCTCCTCCTCCACGGC
TCTGTCGGTGGCCAACTGCCTGGGCGCTCAGACGGTCCAGGCCCCCGCAGAGCCCGCGGCGGGCAAGGCCGAGCAGGGCGAGACCTCTGG
GCGGGAGGCCCCGGAAGCCCCCGCCGTGGGCCGGGAGGACGCGTCAGCCGAGGACTCATGCGCAGAGGCTGCGGCTAGTGGGGCGGCGGA
TGGGGCCACAGCCCCCAAAACAGAGGAGGAAGAGGAGGAGGAGGAGACGGCGGAGGTGGGGAGAGGGGCCGAGGCCGAGGCAGGCGACTT
GGAGCAGCTGAGCAGCAGCAGCACGTCCACCAAGTCCGCCAAGTCAGGCTCGGAGGCGTCGGCCTCCGCCTCCAAGGACGCCCTGCAGGC
CATGATCCTGAGCCTGCCGCGCTACCACTGCGAGAACCCAGCCAGCTGCAAGTCGCCCACGCTCTCCACCGACACCCTGCGCAAGCGGCT
CTACCGCATCGGCCTCAACCTCTTCAACATAAACCCCGACAAGGGCATCCAGTTCCTGATCTCACGCGGCTTCATCCCGGACACCCCCAT
CGGTGTGGCCCATTTCCTCCTCCAGCGAAAGGGCCTCAGCCGCCAGATGATTGGAGAGTTCCTGGGCAACAGCAAGAAGCAGTTCAACCG
CGACGTGCTGGACTGCGTGGTGGACGAGATGGACTTCTCCAGCATGGAGCTGGACGAGGCCCTGCGCAAGTTCCAGGCACACATCCGTGT
GCAGGGGGAGGCTCAGAAGGTGGAGCGGCTCATTGAGGCCTTCAGCCAGCGCTACTGCATGTGCAACCCCGAAGTGGTTCAGCAGTTCCA
CAACCCCGACACCATCTTCATCCTCGCCTTCGCCATCATCCTCCTCAACACCGACATGTACAGCCCCAACATCAAGCCTGACCGGAAGAT
GATGCTGGAGGACTTCATCCGAAACCTTCGAGGTGTGGACGATGGCGCTGACATCCCCAGGGAGCTGGTGGTAGGCATCTATGAGAGGAT
ACAGCAGAAGGAGCTCAAGTCCAATGAGGACCACGTCACGTACGTCACCAAGGTGGAGAAGTCCATTGTGGGCATGAAGACAGTGCTGTC
CGTGCCCCACCGCCGCCTGGTGTGCTGCAGCCGGCTCTTCGAGGTGACGGATGTGAACAAGCTGCAGAAGCAGGCAGCGCATCAGAGGGA
GGTGTTCCTCTTCAATGACCTGCTGGTGATTCTCAAACTTTGCCCGAAGAAGAAGAGCTCCTCCACGTACACCTTTTGCAAGTCAGTTGG
CCTGCTGGGCATGCAGTTCCAGCTCTTTGAGAACGAGTATTACTCTCATGGCATCACACTGGTGACCCCGCTCTCGGGCTCCGAGAAGAA
GCAGGTGCTGCATTTCTGTGCCCTGGGCTCGGACGAGATGCAGAAGTTCGTGGAGGACCTGAAGGAGTCCATTGCTGAGGTGACGGAGCT
GGAGCAGATCCGAATAGAGTGGGAGCTGGAGAAGCAGCAGGGAACAAAGACACTCTCCTTCAAGCCCTGCGGAGCCCAGGGGGACCCACA
GTCAAAGCAAGGATCGCCGACAGCCAAAAGGGAAGCCGCGCTCAGGGAGAGGCCGGCGGAGAGCACGGTGGAGGTGTCAATTCACAACAG
GCTTCAAACGTCCCAGCACAACTCCGGGCTGGGGGCCGAGAGGGGAGCGCCGGTGCCGCCGCCAGACCTGCAGCCTAGCCCCCCGAGACA
GCAGACCCCACCACTGCCGCCGCCGCCACCCACGCCCCCGGGCACCCTGGTGCAGTGCCAGCAAATTGTCAAGGTCATTGTCCTGGACAA
GCCCTGCCTGGCCCGCATGGAGCCCCTGCTGAGCCAGGCTCTCTCCTGCTACACCTCGTCGTCCTCTGACTCCTGCGGCTCCACACCCCT
GGGCGGTCCCGGCTCTCCGGTCAAGGTCACCCACCAGCCTCCGCTGCCCCCGCCCCCACCCCCCTACAACCACCCTCACCAGTTCTGTCC
CCCAGGCTCCCTGCTGCACGGGCACCGCTACTCCAGTGGCTCAAGGAGCCTGGTGTAGACTCTGCCCCACCACCCTGCTGTCCTGGGAGG
GCTGGCCACTGGGGGGCCTGGGCTGCCCCTCCACTGCTCCCCATACCCTGGCACGATGCGTTCCTGGTCACTGATCACCATCATTTTGGG
AAGAGAATCCCAATCCCTGGCACCTGGGTTTGCCTCATCCAACCATCCTTCCCTTTCTCAGCTGCACCCCCTCTGCAGATCTGAAGACAC
ACCTCACTCTCCCAGGGCCCTACACAGCCAGACCCGGCGAGGCCTCCTCTTCCCCTGGCCACCACTTTCCCCCATTGGACCATGGACTGA
AGAAAACGAGCTGAGGGTCTAACGAGCTTGCAGGCTTTGAGTCTGTTAGTGCCCGGGGCCTCGGGCCTTGGGCAGCAGCATGAGGCTGGG
CCGGCCGGCAGTGGAGCACTAGACAGAGTGGCTGGCTCGCAGCCCAGAACTAGTGCCTCTGTAGCTGCACTGAGGGGAGGAGGGTTGGTC
CCACCCCTGGAGGGACAGGTGGGAGGAGTGAGGAGGGGGCTTTTTCTGCCACCCCCGCCCCCAAGCCTGAAACTCTCAGGAGTCTACTTC
TTGGTCCCCAGGGACATTGGCTGTCCTGACCATGTCCTTCCCCCTCCTCCCAGGGCCTCTGCTTCCTCAGGAGCTGCCCAGACTCCAGAA
AAGCCTGGAAAAAGGGAGGCGGGAAGGGGAGCACTTTCGGCTTTCTATAGGTCAGTCCAGCAGGGCCACGGGATCGCGAGGTCATGTATC
TGCAAAATGCACCTTTTTAAAGAGTGTCTTAGTTCCCCAGCCCCAGCTAATACCCGGCCAATGCCGTGTACGCACCGGCATGTGCACGCA
AACACGCATGAGAACCAGGCCATTCCTTCCGCTGTGGAAGCAGAACTGGAGACGGGGCAGGAATGTGCCCAGCAGAGATGGGGCTCAGCC
CGAGGCAGGGCTCCCTCCTGCATGAGGCTCGGCCCGAGGCAGGGCTCCCTCCTGCATGAGTCTGTGGCCTCCAGGAGGGACTTGGGTGCA
GATGTAAGCAAGAAAAACCGGGGCTCCAGAGGCATGTGCATTTCCCCTGCGCCCCTCAGCCTTTAAATATTCCCTCCTCCTAGAAGGTTC
TAGACCCCCCCCTTCCAGCAGGGGTGCCCAAGAGTCCCTGGACCCTCAAAATTGCAAAGGAGACCCAAGCGGGGCTCGCTGACCTCCCAG
GGCCCAGCAAGATGGGATAGCCAGCCTTAGGTGGCCCCACGAGCCCAAGCCTGGGGAAGGGCCCCTCCCCAGCCAGACGAGAGGCAGCCA
CCCCAGAGACCACAGGAGCCGTACCATGGCCTGCGCAGTCAGGCCCTATCAGGATGTGTCTGTCCCAAGCCTGGCCAGGCTCCAGTCCTG
TGCCAGTAGCTCACTGCTGTCCTATGTGCAGGTCCCCCAACACTTGGAGCCTGTGGTTAAGGCCTCCTGGGAGAGGCAGTGAGCATGAGT
CAAAGGTGACATGGACTTGAATCTCCCCACCCCGCCCCGCCTGCAGTAGCCGGGCCAGGTAGGAGGCAAGGATCATTCCCTGCTCCCAGA
GGTTCCAGATGACCTAGTTTCGTTTTGTGTGTGTGTGTGTGTGGTCACCCAGACGTCACTGTGATATCACCTAGTGAATCTATTTCTGGC
CCTGTCTTCGTCGGCCCAGTTTCTGTAACTTGCAGCCAATTTGCCCTCTCCCCTGTGGCTGCCAGCCCATCTGCCCCTCTGTGTCCTTGC
TGCCCTGGCCCTCCTCTGTTTTCTGTAACAGATGCTCCAGTCATTGCCTTTCAGAGTGGAGCAGATGACAGATGGGGTGCACGCATTCAG
ACACCTCTGATGCCCTTAGCCAGGGCAGGGATCGTCCTTAAAGTGAAGGCCTGGACAGGAGGAGTCAGGGACTTGGGAGGAGGTGGAGCT
GTGGGGATGGGAGTGGAGGAATCAAAATGAGGGAAGCTGAAAATAGAATGAAAACGATGACTAAGAGGCAGGGAGTGCGAGGTATGGGGG
AATAGGAACTATGAGCTAAATATACTTATGGGGTGGGGGCCGTGGGGGCCAGGGACACTCTCCCAGACAGCCCTGACCCGCCAGGCAGGA
CCCCGTCCCCTGCTCACACAGCTCTTCAAACTTACCAAGGACAGGCAGGACCCCGTCCCCTGCTCACACAGCTCTTCAAGCTTACCAAGT
CCCCTGTTGAGGGCACAGCAACCCCAGGCCCTCCCTCCCACCTCAGCTGAAGCCCCAATCTTCCAAATCGGAACCAGCAAGTCTTAGGGC
TGGCACGCATCTGGGCCTCTAGCTGAGAACCCGGACTCTCAGGCACCTCAGTGCCCCTGCCCCAGGGCAGAGGCCCACCCCGTGGGTTGG
TGCAGTGGCTGCCCTGGGCTCCACGGGCAGCACAGGGAGTCTGTCCAGGAAGCAGCCCAGCCGGGGTCAGTATTCCGTGGAGCCAGTCCT
GAGCTGGGAGGGGCATTTAACACCCCTGAGGGCCTGGGGCAGGACACAGCTGGCCCTCCTCATTGTCAGGGGAAGCAAGTGCCCAACATC
TGTAACCTCCCTTCCCTGCTCAGTCCCCAGGCCAAGGTTGGGACCCCTCTCCATCCCTGTCCCCAGAGCCTAGACCTCAGGGACCTAGGA
AAAGCCTCCTGCTCCCTCCCCACGGCAGCAGACAGGGCAGGGCCTCCAGCCCCCAGAGGGCCGGTGGGGGGTGCTCTCGGGCCTTCCTGC
TCTCCTAAGGTTGCGGGGACAGTAGAGTGCTGAGCCCCAGACCCAGTCACCCCAAGATGGCCCCACTCTATCCACTCTCTAGACCTTTGG
GAAATCTGGGTCCCTCTCCTGATTTGATCCATTCGGCCCCAACTCCAGAGTCGGGAATGGGAGATGAAACTAGTTTTCCACCCACTTTTG
GACAAGTCCCACCCCTAGATCTGAAGCAAGCTCTACCAGCAGCGTGTCCTGGAAGCCTGCCTGCCTGCCTGCCCGTCTGCACAGGTGTCT
TGATCCAGCCCTGCGTCTTCGAGCCCCTGTGCCACCGGTCCCCACGGCCCGCCAGGAGTCTCTTTGTACCCACTAGGCTTCCCTGATGAC
CATCTGTCTGTCCGTCCCTGTTTTTGCTGTACATAACTCCTGCTGCACCCTCTCCCCGCACACCCGTCACCCATGAGAGAGAGAAACCTC
TCTAGGGAAAGGCAGGGTGGCTGCACCCAGCAACTAATCCAAATGGCAAATATTTTGTAACAAAATAGCCCAGAGGTATTTTATCTGTTC

>99331_99331_13_WNK1-IQSEC3_WNK1_chr12_863490_ENST00000535572_IQSEC3_chr12_247432_ENST00000326261_length(amino acids)=1183AA_BP=300
MSVLSEASSGSARTRPAAVPCRPLRGRLGPSRPFRSRIRARSPLSSEPTMSGGAAEKQSSTPGSLFLSPPAPAPKNGSSSDSSVGEKLGA
AAADAVTGRTEEYRRRRHTMDKDSRGAAATTTTTEHRFFRRSVICDSNATALELPGLPLSLPQPSIPAAVPQSAPPEPHREETVTATATS
QVAQQPPAAAAPGEQAVAGPAPSTVPSSTSKDRPVSQPSLVGSKEEPPPARSGSGGGSAKEPQEERSQQQDDIEELETKAVGMSNDGRFL
KFDIEIGRGSFKTVYKGLDTETTVEVAWCELQIEMLEHKYGGHLVSRRAACTIQTAFRQYQLSKNFEKIRNSLLESRLPRRISLRKVRSP
TAESLAAEKALMEGYGLVGLPLVRSPSLPPTFAGTLTELEDSFTEQVQSLAKSIDDALSTWSLKTMCSLRESGAYQLHQALQAAAGPPGL
EAEGRAPESAGPGPGDDAAETPGLPPAHSGTLMMAFRDVTVQIANQNISVSSSTALSVANCLGAQTVQAPAEPAAGKAEQGETSGREAPE
APAVGREDASAEDSCAEAAASGAADGATAPKTEEEEEEEETAEVGRGAEAEAGDLEQLSSSSTSTKSAKSGSEASASASKDALQAMILSL
PRYHCENPASCKSPTLSTDTLRKRLYRIGLNLFNINPDKGIQFLISRGFIPDTPIGVAHFLLQRKGLSRQMIGEFLGNSKKQFNRDVLDC
VVDEMDFSSMELDEALRKFQAHIRVQGEAQKVERLIEAFSQRYCMCNPEVVQQFHNPDTIFILAFAIILLNTDMYSPNIKPDRKMMLEDF
IRNLRGVDDGADIPRELVVGIYERIQQKELKSNEDHVTYVTKVEKSIVGMKTVLSVPHRRLVCCSRLFEVTDVNKLQKQAAHQREVFLFN
DLLVILKLCPKKKSSSTYTFCKSVGLLGMQFQLFENEYYSHGITLVTPLSGSEKKQVLHFCALGSDEMQKFVEDLKESIAEVTELEQIRI
EWELEKQQGTKTLSFKPCGAQGDPQSKQGSPTAKREAALRERPAESTVEVSIHNRLQTSQHNSGLGAERGAPVPPPDLQPSPPRQQTPPL
PPPPPTPPGTLVQCQQIVKVIVLDKPCLARMEPLLSQALSCYTSSSSDSCGSTPLGGPGSPVKVTHQPPLPPPPPPYNHPHQFCPPGSLL

--------------------------------------------------------------
>99331_99331_14_WNK1-IQSEC3_WNK1_chr12_863490_ENST00000535572_IQSEC3_chr12_247432_ENST00000538872_length(transcript)=7805nt_BP=1732nt
ATTTAGCGCGGAGAGTTTCCCGGGTGGACGCGGCTCCTCTCTCGGCCACTCCGCACCCCCATCTTCGGTGACAGAAGGCGCCTGGTGGGG
GTGGCTGCTCTTTTCTCTCCCTGTTCCCCCTCACCCAGTCCTCTAGGTCTCCTCTCCTCTTGCCTCAGAGAAGCAGCGGAGCTCGGGCCC
CGCGGTGAGCGGCCCTCCCCTCCCCGCCGTTCCCTCCTCCGTCAGCCCCCGGCACCGGCCCGGGAGGAGACGGGTTTGCCAGGCCTGGGG
CGGGCGGGGAGGCCTCGGGGAAGGGGGGGCCCGCTCCTCAGGCGCCGAGGCTCCGAGGCTCCGGCCCTTCGCCTCTGGGCGATGGGCGAC
CTGTGAGGCCGGTCCCCATCGCTGGGGGCGCGTGTGGGAGGAGGCGGCCGCCCGAGTGACCGGGAGCCGGGCCGCGGCCTTCCCTCGCCC
GCCTCGGCCCCTCCCACTCCTCTGCCCCGGGGCCGCCACCGCCCGGGCGTCGGACCTGGTCCCGTGCTCGCGGTGCCGCCGCCCTCTGGG
CCTAGCCCGCCCAGCTCGGCGAGCGGCGGCAGTGGGAGCCGCGTCCGCCGCATCCGCCTCGACTCGGTGCCGGCCCCTGGCCCTCCCCTC
ATGACTGCGGCGCCTCTGCTGCCACCGCCCGCCCGGCCGCCGCTCGCCGCAGGATGGATGCGGACCGTGCGGCGCTAACCCCCGTGGCTC
AGCTCCCGAATCGCCCGCCTTCGAGCCCTCCTCGTGAGCCGCAGCAGCCTCGGTGCCAGCCCCCGCCGCAGCTGGGCCCAGCGGTCCGCC
TGTCCCTCGTTGCGGCTTGTCGGTGCTGAGTGAGGCGTCGTCCGGGTCGGCGCGAACCCGCCCGGCCGCGGTTCCCTGCAGACCTCTGCG
CGGGCGGCTCGGCCCTTCACGCCCTTTTCGTTCACGAATCCGAGCCCGCTCGCCTCTCTCCAGCGAACCGACCATGTCTGGCGGCGCCGC
AGAGAAGCAGAGCAGCACTCCCGGTTCCCTGTTCCTCTCGCCGCCGGCTCCTGCCCCCAAGAATGGCTCCAGCTCCGATTCCTCCGTGGG
GGAGAAACTGGGAGCCGCGGCCGCCGACGCTGTGACCGGCAGGACCGAGGAGTACAGGCGCCGCCGCCACACTATGGACAAGGACAGCCG
TGGGGCGGCCGCGACCACTACCACCACTGAGCACCGCTTCTTCCGCCGGAGCGTCATCTGTGACTCCAATGCCACTGCACTGGAGCTTCC
CGGCCTTCCTCTTTCCCTGCCCCAGCCCAGCATCCCCGCGGCTGTCCCGCAGAGTGCTCCACCGGAGCCCCACCGGGAAGAGACCGTGAC
CGCCACCGCCACTTCCCAGGTAGCCCAGCAGCCTCCAGCCGCTGCCGCCCCTGGGGAACAGGCCGTCGCGGGCCCTGCCCCCTCGACTGT
CCCCAGCAGTACCAGCAAAGACCGCCCAGTGTCCCAGCCTAGCCTTGTGGGGAGCAAAGAGGAGCCGCCGCCGGCGAGAAGTGGCAGCGG
CGGCGGCAGCGCCAAGGAGCCACAGGAGGAACGGAGCCAGCAGCAGGATGATATCGAAGAGCTGGAGACCAAGGCCGTGGGAATGTCTAA
CGATGGCCGCTTTCTCAAGTTTGACATCGAAATCGGCAGAGGCTCCTTTAAGACGGTCTACAAAGGTCTGGACACTGAAACCACCGTGGA
AGTCGCCTGGTGTGAACTGCAGATTGAAATGCTAGAACATAAGTACGGCGGTCACCTGGTGTCCCGGCGCGCCGCTTGCACCATCCAAAC
CGCCTTCCGCCAATACCAGCTCAGCAAGAACTTCGAGAAAATCCGCAACTCGCTTCTGGAGAGCCGCCTGCCACGGCGGATCTCCCTGCG
CAAGGTGCGGTCACCCACGGCCGAGAGCCTGGCGGCCGAGAAAGCGCTCATGGAGGGCTACGGCCTCGTGGGGCTGCCGCTGGTGCGCTC
GCCCTCCCTGCCGCCCACCTTCGCAGGCACCCTCACCGAGCTGGAGGACTCCTTCACCGAGCAGGTGCAATCCCTGGCCAAGTCCATCGA
CGACGCGCTCAGCACGTGGAGCCTCAAGACCATGTGCTCCCTGCGGGAGAGTGGCGCTTACCAGCTCCACCAGGCCCTGCAGGCGGCCGC
GGGGCCCCCAGGCCTGGAGGCCGAGGGGCGGGCGCCGGAGAGCGCGGGCCCCGGGCCCGGGGATGACGCCGCGGAGACCCCCGGCCTGCC
CCCGGCCCACAGCGGGACCCTCATGATGGCTTTCCGGGACGTCACGGTGCAGATCGCCAACCAGAACATATCCGTCTCCTCCTCCACGGC
TCTGTCGGTGGCCAACTGCCTGGGCGCTCAGACGGTCCAGGCCCCCGCAGAGCCCGCGGCGGGCAAGGCCGAGCAGGGCGAGACCTCTGG
GCGGGAGGCCCCGGAAGCCCCCGCCGTGGGCCGGGAGGACGCGTCAGCCGAGGACTCATGCGCAGAGGCTGCGGCTAGTGGGGCGGCGGA
TGGGGCCACAGCCCCCAAAACAGAGGAGGAAGAGGAGGAGGAGGAGACGGCGGAGGTGGGGAGAGGGGCCGAGGCCGAGGCAGGCGACTT
GGAGCAGCTGAGCAGCAGCAGCACGTCCACCAAGTCCGCCAAGTCAGGCTCGGAGGCGTCGGCCTCCGCCTCCAAGGACGCCCTGCAGGC
CATGATCCTGAGCCTGCCGCGCTACCACTGCGAGAACCCAGCCAGCTGCAAGTCGCCCACGCTCTCCACCGACACCCTGCGCAAGCGGCT
CTACCGCATCGGCCTCAACCTCTTCAACATAAACCCCGACAAGGGCATCCAGTTCCTGATCTCACGCGGCTTCATCCCGGACACCCCCAT
CGGTGTGGCCCATTTCCTCCTCCAGCGAAAGGGCCTCAGCCGCCAGATGATTGGAGAGTTCCTGGGCAACAGCAAGAAGCAGTTCAACCG
CGACGTGCTGGACTGCGTGGTGGACGAGATGGACTTCTCCAGCATGGAGCTGGACGAGGCCCTGCGCAAGTTCCAGGCACACATCCGTGT
GCAGGGGGAGGCTCAGAAGGTGGAGCGGCTCATTGAGGCCTTCAGCCAGCGCTACTGCATGTGCAACCCCGAAGTGGTTCAGCAGTTCCA
CAACCCCGACACCATCTTCATCCTCGCCTTCGCCATCATCCTCCTCAACACCGACATGTACAGCCCCAACATCAAGCCTGACCGGAAGAT
GATGCTGGAGGACTTCATCCGAAACCTTCGAGGTGTGGACGATGGCGCTGACATCCCCAGGGAGCTGGTGGTAGGCATCTATGAGAGGAT
ACAGCAGAAGGAGCTCAAGTCCAATGAGGACCACGTCACGTACGTCACCAAGGTGGAGAAGTCCATTGTGGGCATGAAGACAGTGCTGTC
CGTGCCCCACCGCCGCCTGGTGTGCTGCAGCCGGCTCTTCGAGGTGACGGATGTGAACAAGCTGCAGAAGCAGGCAGCGCATCAGAGGGA
GGTGTTCCTCTTCAATGACCTGCTGGTGATTCTCAAACTTTGCCCGAAGAAGAAGAGCTCCTCCACGTACACCTTTTGCAAGTCAGTTGG
CCTGCTGGGCATGCAGTTCCAGCTCTTTGAGAACGAGTATTACTCTCATGGCATCACACTGGTGACCCCGCTCTCGGGCTCCGAGAAGAA
GCAGGTGCTGCATTTCTGTGCCCTGGGCTCGGACGAGATGCAGAAGTTCGTGGAGGACCTGAAGGAGTCCATTGCTGAGGTGACGGAGCT
GGAGCAGATCCGAATAGAGTGGGAGCTGGAGAAGCAGCAGGGAACAAAGACACTCTCCTTCAAGCCCTGCGGAGCCCAGGGGGACCCACA
GTCAAAGCAAGGATCGCCGACAGCCAAAAGGGAAGCCGCGCTCAGGGAGAGGCCGGCGGAGAGCACGGTGGAGGTGTCAATTCACAACAG
GCTTCAAACGTCCCAGCACAACTCCGGGCTGGGGGCCGAGAGGGGAGCGCCGGTGCCGCCGCCAGACCTGCAGCCTAGCCCCCCGAGACA
GCAGACCCCACCACTGCCGCCGCCGCCACCCACGCCCCCGGGCACCCTGGTGCAGTGCCAGCAAATTGTCAAGGTCATTGTCCTGGACAA
GCCCTGCCTGGCCCGCATGGAGCCCCTGCTGAGCCAGGCTCTCTCCTGCTACACCTCGTCGTCCTCTGACTCCTGCGGCTCCACACCCCT
GGGCGGTCCCGGCTCTCCGGTCAAGGTCACCCACCAGCCTCCGCTGCCCCCGCCCCCACCCCCCTACAACCACCCTCACCAGTTCTGTCC
CCCAGGCTCCCTGCTGCACGGGCACCGCTACTCCAGTGGCTCAAGGAGCCTGGTGTAGACTCTGCCCCACCACCCTGCTGTCCTGGGAGG
GCTGGCCACTGGGGGGCCTGGGCTGCCCCTCCACTGCTCCCCATACCCTGGCACGATGCGTTCCTGGTCACTGATCACCATCATTTTGGG
AAGAGAATCCCAATCCCTGGCACCTGGGTTTGCCTCATCCAACCATCCTTCCCTTTCTCAGCTGCACCCCCTCTGCAGATCTGAAGACAC
ACCTCACTCTCCCAGGGCCCTACACAGCCAGACCCGGCGAGGCCTCCTCTTCCCCTGGCCACCACTTTCCCCCATTGGACCATGGACTGA
AGAAAACGAGCTGAGGGTCTAACGAGCTTGCAGGCTTTGAGTCTGTTAGTGCCCGGGGCCTCGGGCCTTGGGCAGCAGCATGAGGCTGGG
CCGGCCGGCAGTGGAGCACTAGACAGAGTGGCTGGCTCGCAGCCCAGAACTAGTGCCTCTGTAGCTGCACTGAGGGGAGGAGGGTTGGTC
CCACCCCTGGAGGGACAGGTGGGAGGAGTGAGGAGGGGGCTTTTTCTGCCACCCCCGCCCCCAAGCCTGAAACTCTCAGGAGTCTACTTC
TTGGTCCCCAGGGACATTGGCTGTCCTGACCATGTCCTTCCCCCTCCTCCCAGGGCCTCTGCTTCCTCAGGAGCTGCCCAGACTCCAGAA
AAGCCTGGAAAAAGGGAGGCGGGAAGGGGAGCACTTTCGGCTTTCTATAGGTCAGTCCAGCAGGGCCACGGGATCGCGAGGTCATGTATC
TGCAAAATGCACCTTTTTAAAGAGTGTCTTAGTTCCCCAGCCCCAGCTAATACCCGGCCAATGCCGTGTACGCACCGGCATGTGCACGCA
AACACGCATGAGAACCAGGCCATTCCTTCCGCTGTGGAAGCAGAACTGGAGACGGGGCAGGAATGTGCCCAGCAGAGATGGGGCTCAGCC
CGAGGCAGGGCTCCCTCCTGCATGAGGCTCGGCCCGAGGCAGGGCTCCCTCCTGCATGAGTCTGTGGCCTCCAGGAGGGACTTGGGTGCA
GATGTAAGCAAGAAAAACCGGGGCTCCAGAGGCATGTGCATTTCCCCTGCGCCCCTCAGCCTTTAAATATTCCCTCCTCCTAGAAGGTTC
TAGACCCCCCCCTTCCAGCAGGGGTGCCCAAGAGTCCCTGGACCCTCAAAATTGCAAAGGAGACCCAAGCGGGGCTCGCTGACCTCCCAG
GGCCCAGCAAGATGGGATAGCCAGCCTTAGGTGGCCCCACGAGCCCAAGCCTGGGGAAGGGCCCCTCCCCAGCCAGACGAGAGGCAGCCA
CCCCAGAGACCACAGGAGCCGTACCATGGCCTGCGCAGTCAGGCCCTATCAGGATGTGTCTGTCCCAAGCCTGGCCAGGCTCCAGTCCTG
TGCCAGTAGCTCACTGCTGTCCTATGTGCAGGTCCCCCAACACTTGGAGCCTGTGGTTAAGGCCTCCTGGGAGAGGCAGTGAGCATGAGT
CAAAGGTGACATGGACTTGAATCTCCCCACCCCGCCCCGCCTGCAGTAGCCGGGCCAGGTAGGAGGCAAGGATCATTCCCTGCTCCCAGA
GGTTCCAGATGACCTAGTTTCGTTTTGTGTGTGTGTGTGTGTGGTCACCCAGACGTCACTGTGATATCACCTAGTGAATCTATTTCTGGC
CCTGTCTTCGTCGGCCCAGTTTCTGTAACTTGCAGCCAATTTGCCCTCTCCCCTGTGGCTGCCAGCCCATCTGCCCCTCTGTGTCCTTGC
TGCCCTGGCCCTCCTCTGTTTTCTGTAACAGATGCTCCAGTCATTGCCTTTCAGAGTGGAGCAGATGACAGATGGGGTGCACGCATTCAG
ACACCTCTGATGCCCTTAGCCAGGGCAGGGATCGTCCTTAAAGTGAAGGCCTGGACAGGAGGAGTCAGGGACTTGGGAGGAGGTGGAGCT
GTGGGGATGGGAGTGGAGGAATCAAAATGAGGGAAGCTGAAAATAGAATGAAAACGATGACTAAGAGGCAGGGAGTGCGAGGTATGGGGG
AATAGGAACTATGAGCTAAATATACTTATGGGGTGGGGGCCGTGGGGGCCAGGGACACTCTCCCAGACAGCCCTGACCCGCCAGGCAGGA
CCCCGTCCCCTGCTCACACAGCTCTTCAAACTTACCAAGGACAGGCAGGACCCCGTCCCCTGCTCACACAGCTCTTCAAGCTTACCAAGG
ACAGGCAGAACCCCGTCCCCTGCTCACACAGCTCTTCAAGCTTACCAAGGACAGGCAGGACCCCGTCCCCTGCTCACACAGCTCTTCAAA
CTTACCAAGTGCCCTCTCCCCTGTTGAGGGCACAGCAACCCCAGGCCCTCCCTCCCACCTCAGCTGAAGCCCCAATCTTCCAAATCGGAA
CCAGCAAGTCTTAGGGCTGGCACGCATCTGGGCCTCTAGCTGAGAACCCGGACTCTCAGGCACCTCAGTGCCCCTGCCCCAGGGCAGAGG
CCCACCCCGTGGGTTGGTGCAGTGGCTGCCCTGGGCTCCACGGGCAGCACAGGGAGTCTGTCCAGGAAGCAGCCCAGCCGGGGTCAGTAT
TCCGTGGAGCCAGTCCTGAGCTGGGAGGGGCATTTAACACCCCTGAGGGCCTGGGGCAGGACACAGCTGGCCCTCCTCATTGTCAGGGGA
AGCAAGTGCCCAACATCTGTAACCTCCCTTCCCTGCTCAGTCCCCAGGCCAAGGTTGGGACCCCTCTCCATCCCTGTCCCCAGAGCCTAG
ACCTCAGGGACCTAGGAAAAGCCTCCTGCTCCCTCCCCACGGCAGCAGACAGGGCAGGGCCTCCAGCCCCCAGAGGGCCGGTGGGGGGTG
CTCTCGGGCCTTCCTGCTCTCCTAAGGTTGCGGGGACAGTAGAGTGCTGAGCCCCAGACCCAGTCACCCCAAGATGGCCCCACTCTATCC
ACTCTCTAGACCTTTGGGAAATCTGGGTCCCTCTCCTGATTTGATCCATTCGGCCCCAACTCCAGAGTCGGGAATGGGAGATGAAACTAG
TTTTCCACCCACTTTTGGACAAGTCCCACCCCTAGATCTGAAGCAAGCTCTACCAGCAGCGTGTCCTGGAAGCCTGCCTGCCTGCCTGCC
CGTCTGCACAGGTGTCTTGATCCAGCCCTGCGTCTTCGAGCCCCTGTGCCACCGGTCCCCACGGCCCGCCAGGAGTCTCTTTGTACCCAC
TAGGCTTCCCTGATGACCATCTGTCTGTCCGTCCCTGTTTTTGCTGTACATAACTCCTGCTGCACCCTCTCCCCGCACACCCGTCACCCA
TGAGAGAGAGAAACCTCTCTAGGGAAAGGCAGGGTGGCTGCACCCAGCAACTAATCCAAATGGCAAATATTTTGTAACAAAATAGCCCAG

>99331_99331_14_WNK1-IQSEC3_WNK1_chr12_863490_ENST00000535572_IQSEC3_chr12_247432_ENST00000538872_length(amino acids)=1183AA_BP=300
MSVLSEASSGSARTRPAAVPCRPLRGRLGPSRPFRSRIRARSPLSSEPTMSGGAAEKQSSTPGSLFLSPPAPAPKNGSSSDSSVGEKLGA
AAADAVTGRTEEYRRRRHTMDKDSRGAAATTTTTEHRFFRRSVICDSNATALELPGLPLSLPQPSIPAAVPQSAPPEPHREETVTATATS
QVAQQPPAAAAPGEQAVAGPAPSTVPSSTSKDRPVSQPSLVGSKEEPPPARSGSGGGSAKEPQEERSQQQDDIEELETKAVGMSNDGRFL
KFDIEIGRGSFKTVYKGLDTETTVEVAWCELQIEMLEHKYGGHLVSRRAACTIQTAFRQYQLSKNFEKIRNSLLESRLPRRISLRKVRSP
TAESLAAEKALMEGYGLVGLPLVRSPSLPPTFAGTLTELEDSFTEQVQSLAKSIDDALSTWSLKTMCSLRESGAYQLHQALQAAAGPPGL
EAEGRAPESAGPGPGDDAAETPGLPPAHSGTLMMAFRDVTVQIANQNISVSSSTALSVANCLGAQTVQAPAEPAAGKAEQGETSGREAPE
APAVGREDASAEDSCAEAAASGAADGATAPKTEEEEEEEETAEVGRGAEAEAGDLEQLSSSSTSTKSAKSGSEASASASKDALQAMILSL
PRYHCENPASCKSPTLSTDTLRKRLYRIGLNLFNINPDKGIQFLISRGFIPDTPIGVAHFLLQRKGLSRQMIGEFLGNSKKQFNRDVLDC
VVDEMDFSSMELDEALRKFQAHIRVQGEAQKVERLIEAFSQRYCMCNPEVVQQFHNPDTIFILAFAIILLNTDMYSPNIKPDRKMMLEDF
IRNLRGVDDGADIPRELVVGIYERIQQKELKSNEDHVTYVTKVEKSIVGMKTVLSVPHRRLVCCSRLFEVTDVNKLQKQAAHQREVFLFN
DLLVILKLCPKKKSSSTYTFCKSVGLLGMQFQLFENEYYSHGITLVTPLSGSEKKQVLHFCALGSDEMQKFVEDLKESIAEVTELEQIRI
EWELEKQQGTKTLSFKPCGAQGDPQSKQGSPTAKREAALRERPAESTVEVSIHNRLQTSQHNSGLGAERGAPVPPPDLQPSPPRQQTPPL
PPPPPTPPGTLVQCQQIVKVIVLDKPCLARMEPLLSQALSCYTSSSSDSCGSTPLGGPGSPVKVTHQPPLPPPPPPYNHPHQFCPPGSLL

--------------------------------------------------------------
>99331_99331_15_WNK1-IQSEC3_WNK1_chr12_863490_ENST00000535572_IQSEC3_chr12_247433_ENST00000326261_length(transcript)=7692nt_BP=1732nt
ATTTAGCGCGGAGAGTTTCCCGGGTGGACGCGGCTCCTCTCTCGGCCACTCCGCACCCCCATCTTCGGTGACAGAAGGCGCCTGGTGGGG
GTGGCTGCTCTTTTCTCTCCCTGTTCCCCCTCACCCAGTCCTCTAGGTCTCCTCTCCTCTTGCCTCAGAGAAGCAGCGGAGCTCGGGCCC
CGCGGTGAGCGGCCCTCCCCTCCCCGCCGTTCCCTCCTCCGTCAGCCCCCGGCACCGGCCCGGGAGGAGACGGGTTTGCCAGGCCTGGGG
CGGGCGGGGAGGCCTCGGGGAAGGGGGGGCCCGCTCCTCAGGCGCCGAGGCTCCGAGGCTCCGGCCCTTCGCCTCTGGGCGATGGGCGAC
CTGTGAGGCCGGTCCCCATCGCTGGGGGCGCGTGTGGGAGGAGGCGGCCGCCCGAGTGACCGGGAGCCGGGCCGCGGCCTTCCCTCGCCC
GCCTCGGCCCCTCCCACTCCTCTGCCCCGGGGCCGCCACCGCCCGGGCGTCGGACCTGGTCCCGTGCTCGCGGTGCCGCCGCCCTCTGGG
CCTAGCCCGCCCAGCTCGGCGAGCGGCGGCAGTGGGAGCCGCGTCCGCCGCATCCGCCTCGACTCGGTGCCGGCCCCTGGCCCTCCCCTC
ATGACTGCGGCGCCTCTGCTGCCACCGCCCGCCCGGCCGCCGCTCGCCGCAGGATGGATGCGGACCGTGCGGCGCTAACCCCCGTGGCTC
AGCTCCCGAATCGCCCGCCTTCGAGCCCTCCTCGTGAGCCGCAGCAGCCTCGGTGCCAGCCCCCGCCGCAGCTGGGCCCAGCGGTCCGCC
TGTCCCTCGTTGCGGCTTGTCGGTGCTGAGTGAGGCGTCGTCCGGGTCGGCGCGAACCCGCCCGGCCGCGGTTCCCTGCAGACCTCTGCG
CGGGCGGCTCGGCCCTTCACGCCCTTTTCGTTCACGAATCCGAGCCCGCTCGCCTCTCTCCAGCGAACCGACCATGTCTGGCGGCGCCGC
AGAGAAGCAGAGCAGCACTCCCGGTTCCCTGTTCCTCTCGCCGCCGGCTCCTGCCCCCAAGAATGGCTCCAGCTCCGATTCCTCCGTGGG
GGAGAAACTGGGAGCCGCGGCCGCCGACGCTGTGACCGGCAGGACCGAGGAGTACAGGCGCCGCCGCCACACTATGGACAAGGACAGCCG
TGGGGCGGCCGCGACCACTACCACCACTGAGCACCGCTTCTTCCGCCGGAGCGTCATCTGTGACTCCAATGCCACTGCACTGGAGCTTCC
CGGCCTTCCTCTTTCCCTGCCCCAGCCCAGCATCCCCGCGGCTGTCCCGCAGAGTGCTCCACCGGAGCCCCACCGGGAAGAGACCGTGAC
CGCCACCGCCACTTCCCAGGTAGCCCAGCAGCCTCCAGCCGCTGCCGCCCCTGGGGAACAGGCCGTCGCGGGCCCTGCCCCCTCGACTGT
CCCCAGCAGTACCAGCAAAGACCGCCCAGTGTCCCAGCCTAGCCTTGTGGGGAGCAAAGAGGAGCCGCCGCCGGCGAGAAGTGGCAGCGG
CGGCGGCAGCGCCAAGGAGCCACAGGAGGAACGGAGCCAGCAGCAGGATGATATCGAAGAGCTGGAGACCAAGGCCGTGGGAATGTCTAA
CGATGGCCGCTTTCTCAAGTTTGACATCGAAATCGGCAGAGGCTCCTTTAAGACGGTCTACAAAGGTCTGGACACTGAAACCACCGTGGA
AGTCGCCTGGTGTGAACTGCAGATTGAAATGCTAGAACATAAGTACGGCGGTCACCTGGTGTCCCGGCGCGCCGCTTGCACCATCCAAAC
CGCCTTCCGCCAATACCAGCTCAGCAAGAACTTCGAGAAAATCCGCAACTCGCTTCTGGAGAGCCGCCTGCCACGGCGGATCTCCCTGCG
CAAGGTGCGGTCACCCACGGCCGAGAGCCTGGCGGCCGAGAAAGCGCTCATGGAGGGCTACGGCCTCGTGGGGCTGCCGCTGGTGCGCTC
GCCCTCCCTGCCGCCCACCTTCGCAGGCACCCTCACCGAGCTGGAGGACTCCTTCACCGAGCAGGTGCAATCCCTGGCCAAGTCCATCGA
CGACGCGCTCAGCACGTGGAGCCTCAAGACCATGTGCTCCCTGCGGGAGAGTGGCGCTTACCAGCTCCACCAGGCCCTGCAGGCGGCCGC
GGGGCCCCCAGGCCTGGAGGCCGAGGGGCGGGCGCCGGAGAGCGCGGGCCCCGGGCCCGGGGATGACGCCGCGGAGACCCCCGGCCTGCC
CCCGGCCCACAGCGGGACCCTCATGATGGCTTTCCGGGACGTCACGGTGCAGATCGCCAACCAGAACATATCCGTCTCCTCCTCCACGGC
TCTGTCGGTGGCCAACTGCCTGGGCGCTCAGACGGTCCAGGCCCCCGCAGAGCCCGCGGCGGGCAAGGCCGAGCAGGGCGAGACCTCTGG
GCGGGAGGCCCCGGAAGCCCCCGCCGTGGGCCGGGAGGACGCGTCAGCCGAGGACTCATGCGCAGAGGCTGCGGCTAGTGGGGCGGCGGA
TGGGGCCACAGCCCCCAAAACAGAGGAGGAAGAGGAGGAGGAGGAGACGGCGGAGGTGGGGAGAGGGGCCGAGGCCGAGGCAGGCGACTT
GGAGCAGCTGAGCAGCAGCAGCACGTCCACCAAGTCCGCCAAGTCAGGCTCGGAGGCGTCGGCCTCCGCCTCCAAGGACGCCCTGCAGGC
CATGATCCTGAGCCTGCCGCGCTACCACTGCGAGAACCCAGCCAGCTGCAAGTCGCCCACGCTCTCCACCGACACCCTGCGCAAGCGGCT
CTACCGCATCGGCCTCAACCTCTTCAACATAAACCCCGACAAGGGCATCCAGTTCCTGATCTCACGCGGCTTCATCCCGGACACCCCCAT
CGGTGTGGCCCATTTCCTCCTCCAGCGAAAGGGCCTCAGCCGCCAGATGATTGGAGAGTTCCTGGGCAACAGCAAGAAGCAGTTCAACCG
CGACGTGCTGGACTGCGTGGTGGACGAGATGGACTTCTCCAGCATGGAGCTGGACGAGGCCCTGCGCAAGTTCCAGGCACACATCCGTGT
GCAGGGGGAGGCTCAGAAGGTGGAGCGGCTCATTGAGGCCTTCAGCCAGCGCTACTGCATGTGCAACCCCGAAGTGGTTCAGCAGTTCCA
CAACCCCGACACCATCTTCATCCTCGCCTTCGCCATCATCCTCCTCAACACCGACATGTACAGCCCCAACATCAAGCCTGACCGGAAGAT
GATGCTGGAGGACTTCATCCGAAACCTTCGAGGTGTGGACGATGGCGCTGACATCCCCAGGGAGCTGGTGGTAGGCATCTATGAGAGGAT
ACAGCAGAAGGAGCTCAAGTCCAATGAGGACCACGTCACGTACGTCACCAAGGTGGAGAAGTCCATTGTGGGCATGAAGACAGTGCTGTC
CGTGCCCCACCGCCGCCTGGTGTGCTGCAGCCGGCTCTTCGAGGTGACGGATGTGAACAAGCTGCAGAAGCAGGCAGCGCATCAGAGGGA
GGTGTTCCTCTTCAATGACCTGCTGGTGATTCTCAAACTTTGCCCGAAGAAGAAGAGCTCCTCCACGTACACCTTTTGCAAGTCAGTTGG
CCTGCTGGGCATGCAGTTCCAGCTCTTTGAGAACGAGTATTACTCTCATGGCATCACACTGGTGACCCCGCTCTCGGGCTCCGAGAAGAA
GCAGGTGCTGCATTTCTGTGCCCTGGGCTCGGACGAGATGCAGAAGTTCGTGGAGGACCTGAAGGAGTCCATTGCTGAGGTGACGGAGCT
GGAGCAGATCCGAATAGAGTGGGAGCTGGAGAAGCAGCAGGGAACAAAGACACTCTCCTTCAAGCCCTGCGGAGCCCAGGGGGACCCACA
GTCAAAGCAAGGATCGCCGACAGCCAAAAGGGAAGCCGCGCTCAGGGAGAGGCCGGCGGAGAGCACGGTGGAGGTGTCAATTCACAACAG
GCTTCAAACGTCCCAGCACAACTCCGGGCTGGGGGCCGAGAGGGGAGCGCCGGTGCCGCCGCCAGACCTGCAGCCTAGCCCCCCGAGACA
GCAGACCCCACCACTGCCGCCGCCGCCACCCACGCCCCCGGGCACCCTGGTGCAGTGCCAGCAAATTGTCAAGGTCATTGTCCTGGACAA
GCCCTGCCTGGCCCGCATGGAGCCCCTGCTGAGCCAGGCTCTCTCCTGCTACACCTCGTCGTCCTCTGACTCCTGCGGCTCCACACCCCT
GGGCGGTCCCGGCTCTCCGGTCAAGGTCACCCACCAGCCTCCGCTGCCCCCGCCCCCACCCCCCTACAACCACCCTCACCAGTTCTGTCC
CCCAGGCTCCCTGCTGCACGGGCACCGCTACTCCAGTGGCTCAAGGAGCCTGGTGTAGACTCTGCCCCACCACCCTGCTGTCCTGGGAGG
GCTGGCCACTGGGGGGCCTGGGCTGCCCCTCCACTGCTCCCCATACCCTGGCACGATGCGTTCCTGGTCACTGATCACCATCATTTTGGG
AAGAGAATCCCAATCCCTGGCACCTGGGTTTGCCTCATCCAACCATCCTTCCCTTTCTCAGCTGCACCCCCTCTGCAGATCTGAAGACAC
ACCTCACTCTCCCAGGGCCCTACACAGCCAGACCCGGCGAGGCCTCCTCTTCCCCTGGCCACCACTTTCCCCCATTGGACCATGGACTGA
AGAAAACGAGCTGAGGGTCTAACGAGCTTGCAGGCTTTGAGTCTGTTAGTGCCCGGGGCCTCGGGCCTTGGGCAGCAGCATGAGGCTGGG
CCGGCCGGCAGTGGAGCACTAGACAGAGTGGCTGGCTCGCAGCCCAGAACTAGTGCCTCTGTAGCTGCACTGAGGGGAGGAGGGTTGGTC
CCACCCCTGGAGGGACAGGTGGGAGGAGTGAGGAGGGGGCTTTTTCTGCCACCCCCGCCCCCAAGCCTGAAACTCTCAGGAGTCTACTTC
TTGGTCCCCAGGGACATTGGCTGTCCTGACCATGTCCTTCCCCCTCCTCCCAGGGCCTCTGCTTCCTCAGGAGCTGCCCAGACTCCAGAA
AAGCCTGGAAAAAGGGAGGCGGGAAGGGGAGCACTTTCGGCTTTCTATAGGTCAGTCCAGCAGGGCCACGGGATCGCGAGGTCATGTATC
TGCAAAATGCACCTTTTTAAAGAGTGTCTTAGTTCCCCAGCCCCAGCTAATACCCGGCCAATGCCGTGTACGCACCGGCATGTGCACGCA
AACACGCATGAGAACCAGGCCATTCCTTCCGCTGTGGAAGCAGAACTGGAGACGGGGCAGGAATGTGCCCAGCAGAGATGGGGCTCAGCC
CGAGGCAGGGCTCCCTCCTGCATGAGGCTCGGCCCGAGGCAGGGCTCCCTCCTGCATGAGTCTGTGGCCTCCAGGAGGGACTTGGGTGCA
GATGTAAGCAAGAAAAACCGGGGCTCCAGAGGCATGTGCATTTCCCCTGCGCCCCTCAGCCTTTAAATATTCCCTCCTCCTAGAAGGTTC
TAGACCCCCCCCTTCCAGCAGGGGTGCCCAAGAGTCCCTGGACCCTCAAAATTGCAAAGGAGACCCAAGCGGGGCTCGCTGACCTCCCAG
GGCCCAGCAAGATGGGATAGCCAGCCTTAGGTGGCCCCACGAGCCCAAGCCTGGGGAAGGGCCCCTCCCCAGCCAGACGAGAGGCAGCCA
CCCCAGAGACCACAGGAGCCGTACCATGGCCTGCGCAGTCAGGCCCTATCAGGATGTGTCTGTCCCAAGCCTGGCCAGGCTCCAGTCCTG
TGCCAGTAGCTCACTGCTGTCCTATGTGCAGGTCCCCCAACACTTGGAGCCTGTGGTTAAGGCCTCCTGGGAGAGGCAGTGAGCATGAGT
CAAAGGTGACATGGACTTGAATCTCCCCACCCCGCCCCGCCTGCAGTAGCCGGGCCAGGTAGGAGGCAAGGATCATTCCCTGCTCCCAGA
GGTTCCAGATGACCTAGTTTCGTTTTGTGTGTGTGTGTGTGTGGTCACCCAGACGTCACTGTGATATCACCTAGTGAATCTATTTCTGGC
CCTGTCTTCGTCGGCCCAGTTTCTGTAACTTGCAGCCAATTTGCCCTCTCCCCTGTGGCTGCCAGCCCATCTGCCCCTCTGTGTCCTTGC
TGCCCTGGCCCTCCTCTGTTTTCTGTAACAGATGCTCCAGTCATTGCCTTTCAGAGTGGAGCAGATGACAGATGGGGTGCACGCATTCAG
ACACCTCTGATGCCCTTAGCCAGGGCAGGGATCGTCCTTAAAGTGAAGGCCTGGACAGGAGGAGTCAGGGACTTGGGAGGAGGTGGAGCT
GTGGGGATGGGAGTGGAGGAATCAAAATGAGGGAAGCTGAAAATAGAATGAAAACGATGACTAAGAGGCAGGGAGTGCGAGGTATGGGGG
AATAGGAACTATGAGCTAAATATACTTATGGGGTGGGGGCCGTGGGGGCCAGGGACACTCTCCCAGACAGCCCTGACCCGCCAGGCAGGA
CCCCGTCCCCTGCTCACACAGCTCTTCAAACTTACCAAGGACAGGCAGGACCCCGTCCCCTGCTCACACAGCTCTTCAAGCTTACCAAGT
CCCCTGTTGAGGGCACAGCAACCCCAGGCCCTCCCTCCCACCTCAGCTGAAGCCCCAATCTTCCAAATCGGAACCAGCAAGTCTTAGGGC
TGGCACGCATCTGGGCCTCTAGCTGAGAACCCGGACTCTCAGGCACCTCAGTGCCCCTGCCCCAGGGCAGAGGCCCACCCCGTGGGTTGG
TGCAGTGGCTGCCCTGGGCTCCACGGGCAGCACAGGGAGTCTGTCCAGGAAGCAGCCCAGCCGGGGTCAGTATTCCGTGGAGCCAGTCCT
GAGCTGGGAGGGGCATTTAACACCCCTGAGGGCCTGGGGCAGGACACAGCTGGCCCTCCTCATTGTCAGGGGAAGCAAGTGCCCAACATC
TGTAACCTCCCTTCCCTGCTCAGTCCCCAGGCCAAGGTTGGGACCCCTCTCCATCCCTGTCCCCAGAGCCTAGACCTCAGGGACCTAGGA
AAAGCCTCCTGCTCCCTCCCCACGGCAGCAGACAGGGCAGGGCCTCCAGCCCCCAGAGGGCCGGTGGGGGGTGCTCTCGGGCCTTCCTGC
TCTCCTAAGGTTGCGGGGACAGTAGAGTGCTGAGCCCCAGACCCAGTCACCCCAAGATGGCCCCACTCTATCCACTCTCTAGACCTTTGG
GAAATCTGGGTCCCTCTCCTGATTTGATCCATTCGGCCCCAACTCCAGAGTCGGGAATGGGAGATGAAACTAGTTTTCCACCCACTTTTG
GACAAGTCCCACCCCTAGATCTGAAGCAAGCTCTACCAGCAGCGTGTCCTGGAAGCCTGCCTGCCTGCCTGCCCGTCTGCACAGGTGTCT
TGATCCAGCCCTGCGTCTTCGAGCCCCTGTGCCACCGGTCCCCACGGCCCGCCAGGAGTCTCTTTGTACCCACTAGGCTTCCCTGATGAC
CATCTGTCTGTCCGTCCCTGTTTTTGCTGTACATAACTCCTGCTGCACCCTCTCCCCGCACACCCGTCACCCATGAGAGAGAGAAACCTC
TCTAGGGAAAGGCAGGGTGGCTGCACCCAGCAACTAATCCAAATGGCAAATATTTTGTAACAAAATAGCCCAGAGGTATTTTATCTGTTC

>99331_99331_15_WNK1-IQSEC3_WNK1_chr12_863490_ENST00000535572_IQSEC3_chr12_247433_ENST00000326261_length(amino acids)=1183AA_BP=300
MSVLSEASSGSARTRPAAVPCRPLRGRLGPSRPFRSRIRARSPLSSEPTMSGGAAEKQSSTPGSLFLSPPAPAPKNGSSSDSSVGEKLGA
AAADAVTGRTEEYRRRRHTMDKDSRGAAATTTTTEHRFFRRSVICDSNATALELPGLPLSLPQPSIPAAVPQSAPPEPHREETVTATATS
QVAQQPPAAAAPGEQAVAGPAPSTVPSSTSKDRPVSQPSLVGSKEEPPPARSGSGGGSAKEPQEERSQQQDDIEELETKAVGMSNDGRFL
KFDIEIGRGSFKTVYKGLDTETTVEVAWCELQIEMLEHKYGGHLVSRRAACTIQTAFRQYQLSKNFEKIRNSLLESRLPRRISLRKVRSP
TAESLAAEKALMEGYGLVGLPLVRSPSLPPTFAGTLTELEDSFTEQVQSLAKSIDDALSTWSLKTMCSLRESGAYQLHQALQAAAGPPGL
EAEGRAPESAGPGPGDDAAETPGLPPAHSGTLMMAFRDVTVQIANQNISVSSSTALSVANCLGAQTVQAPAEPAAGKAEQGETSGREAPE
APAVGREDASAEDSCAEAAASGAADGATAPKTEEEEEEEETAEVGRGAEAEAGDLEQLSSSSTSTKSAKSGSEASASASKDALQAMILSL
PRYHCENPASCKSPTLSTDTLRKRLYRIGLNLFNINPDKGIQFLISRGFIPDTPIGVAHFLLQRKGLSRQMIGEFLGNSKKQFNRDVLDC
VVDEMDFSSMELDEALRKFQAHIRVQGEAQKVERLIEAFSQRYCMCNPEVVQQFHNPDTIFILAFAIILLNTDMYSPNIKPDRKMMLEDF
IRNLRGVDDGADIPRELVVGIYERIQQKELKSNEDHVTYVTKVEKSIVGMKTVLSVPHRRLVCCSRLFEVTDVNKLQKQAAHQREVFLFN
DLLVILKLCPKKKSSSTYTFCKSVGLLGMQFQLFENEYYSHGITLVTPLSGSEKKQVLHFCALGSDEMQKFVEDLKESIAEVTELEQIRI
EWELEKQQGTKTLSFKPCGAQGDPQSKQGSPTAKREAALRERPAESTVEVSIHNRLQTSQHNSGLGAERGAPVPPPDLQPSPPRQQTPPL
PPPPPTPPGTLVQCQQIVKVIVLDKPCLARMEPLLSQALSCYTSSSSDSCGSTPLGGPGSPVKVTHQPPLPPPPPPYNHPHQFCPPGSLL

--------------------------------------------------------------
>99331_99331_16_WNK1-IQSEC3_WNK1_chr12_863490_ENST00000535572_IQSEC3_chr12_247433_ENST00000538872_length(transcript)=7805nt_BP=1732nt
ATTTAGCGCGGAGAGTTTCCCGGGTGGACGCGGCTCCTCTCTCGGCCACTCCGCACCCCCATCTTCGGTGACAGAAGGCGCCTGGTGGGG
GTGGCTGCTCTTTTCTCTCCCTGTTCCCCCTCACCCAGTCCTCTAGGTCTCCTCTCCTCTTGCCTCAGAGAAGCAGCGGAGCTCGGGCCC
CGCGGTGAGCGGCCCTCCCCTCCCCGCCGTTCCCTCCTCCGTCAGCCCCCGGCACCGGCCCGGGAGGAGACGGGTTTGCCAGGCCTGGGG
CGGGCGGGGAGGCCTCGGGGAAGGGGGGGCCCGCTCCTCAGGCGCCGAGGCTCCGAGGCTCCGGCCCTTCGCCTCTGGGCGATGGGCGAC
CTGTGAGGCCGGTCCCCATCGCTGGGGGCGCGTGTGGGAGGAGGCGGCCGCCCGAGTGACCGGGAGCCGGGCCGCGGCCTTCCCTCGCCC
GCCTCGGCCCCTCCCACTCCTCTGCCCCGGGGCCGCCACCGCCCGGGCGTCGGACCTGGTCCCGTGCTCGCGGTGCCGCCGCCCTCTGGG
CCTAGCCCGCCCAGCTCGGCGAGCGGCGGCAGTGGGAGCCGCGTCCGCCGCATCCGCCTCGACTCGGTGCCGGCCCCTGGCCCTCCCCTC
ATGACTGCGGCGCCTCTGCTGCCACCGCCCGCCCGGCCGCCGCTCGCCGCAGGATGGATGCGGACCGTGCGGCGCTAACCCCCGTGGCTC
AGCTCCCGAATCGCCCGCCTTCGAGCCCTCCTCGTGAGCCGCAGCAGCCTCGGTGCCAGCCCCCGCCGCAGCTGGGCCCAGCGGTCCGCC
TGTCCCTCGTTGCGGCTTGTCGGTGCTGAGTGAGGCGTCGTCCGGGTCGGCGCGAACCCGCCCGGCCGCGGTTCCCTGCAGACCTCTGCG
CGGGCGGCTCGGCCCTTCACGCCCTTTTCGTTCACGAATCCGAGCCCGCTCGCCTCTCTCCAGCGAACCGACCATGTCTGGCGGCGCCGC
AGAGAAGCAGAGCAGCACTCCCGGTTCCCTGTTCCTCTCGCCGCCGGCTCCTGCCCCCAAGAATGGCTCCAGCTCCGATTCCTCCGTGGG
GGAGAAACTGGGAGCCGCGGCCGCCGACGCTGTGACCGGCAGGACCGAGGAGTACAGGCGCCGCCGCCACACTATGGACAAGGACAGCCG
TGGGGCGGCCGCGACCACTACCACCACTGAGCACCGCTTCTTCCGCCGGAGCGTCATCTGTGACTCCAATGCCACTGCACTGGAGCTTCC
CGGCCTTCCTCTTTCCCTGCCCCAGCCCAGCATCCCCGCGGCTGTCCCGCAGAGTGCTCCACCGGAGCCCCACCGGGAAGAGACCGTGAC
CGCCACCGCCACTTCCCAGGTAGCCCAGCAGCCTCCAGCCGCTGCCGCCCCTGGGGAACAGGCCGTCGCGGGCCCTGCCCCCTCGACTGT
CCCCAGCAGTACCAGCAAAGACCGCCCAGTGTCCCAGCCTAGCCTTGTGGGGAGCAAAGAGGAGCCGCCGCCGGCGAGAAGTGGCAGCGG
CGGCGGCAGCGCCAAGGAGCCACAGGAGGAACGGAGCCAGCAGCAGGATGATATCGAAGAGCTGGAGACCAAGGCCGTGGGAATGTCTAA
CGATGGCCGCTTTCTCAAGTTTGACATCGAAATCGGCAGAGGCTCCTTTAAGACGGTCTACAAAGGTCTGGACACTGAAACCACCGTGGA
AGTCGCCTGGTGTGAACTGCAGATTGAAATGCTAGAACATAAGTACGGCGGTCACCTGGTGTCCCGGCGCGCCGCTTGCACCATCCAAAC
CGCCTTCCGCCAATACCAGCTCAGCAAGAACTTCGAGAAAATCCGCAACTCGCTTCTGGAGAGCCGCCTGCCACGGCGGATCTCCCTGCG
CAAGGTGCGGTCACCCACGGCCGAGAGCCTGGCGGCCGAGAAAGCGCTCATGGAGGGCTACGGCCTCGTGGGGCTGCCGCTGGTGCGCTC
GCCCTCCCTGCCGCCCACCTTCGCAGGCACCCTCACCGAGCTGGAGGACTCCTTCACCGAGCAGGTGCAATCCCTGGCCAAGTCCATCGA
CGACGCGCTCAGCACGTGGAGCCTCAAGACCATGTGCTCCCTGCGGGAGAGTGGCGCTTACCAGCTCCACCAGGCCCTGCAGGCGGCCGC
GGGGCCCCCAGGCCTGGAGGCCGAGGGGCGGGCGCCGGAGAGCGCGGGCCCCGGGCCCGGGGATGACGCCGCGGAGACCCCCGGCCTGCC
CCCGGCCCACAGCGGGACCCTCATGATGGCTTTCCGGGACGTCACGGTGCAGATCGCCAACCAGAACATATCCGTCTCCTCCTCCACGGC
TCTGTCGGTGGCCAACTGCCTGGGCGCTCAGACGGTCCAGGCCCCCGCAGAGCCCGCGGCGGGCAAGGCCGAGCAGGGCGAGACCTCTGG
GCGGGAGGCCCCGGAAGCCCCCGCCGTGGGCCGGGAGGACGCGTCAGCCGAGGACTCATGCGCAGAGGCTGCGGCTAGTGGGGCGGCGGA
TGGGGCCACAGCCCCCAAAACAGAGGAGGAAGAGGAGGAGGAGGAGACGGCGGAGGTGGGGAGAGGGGCCGAGGCCGAGGCAGGCGACTT
GGAGCAGCTGAGCAGCAGCAGCACGTCCACCAAGTCCGCCAAGTCAGGCTCGGAGGCGTCGGCCTCCGCCTCCAAGGACGCCCTGCAGGC
CATGATCCTGAGCCTGCCGCGCTACCACTGCGAGAACCCAGCCAGCTGCAAGTCGCCCACGCTCTCCACCGACACCCTGCGCAAGCGGCT
CTACCGCATCGGCCTCAACCTCTTCAACATAAACCCCGACAAGGGCATCCAGTTCCTGATCTCACGCGGCTTCATCCCGGACACCCCCAT
CGGTGTGGCCCATTTCCTCCTCCAGCGAAAGGGCCTCAGCCGCCAGATGATTGGAGAGTTCCTGGGCAACAGCAAGAAGCAGTTCAACCG
CGACGTGCTGGACTGCGTGGTGGACGAGATGGACTTCTCCAGCATGGAGCTGGACGAGGCCCTGCGCAAGTTCCAGGCACACATCCGTGT
GCAGGGGGAGGCTCAGAAGGTGGAGCGGCTCATTGAGGCCTTCAGCCAGCGCTACTGCATGTGCAACCCCGAAGTGGTTCAGCAGTTCCA
CAACCCCGACACCATCTTCATCCTCGCCTTCGCCATCATCCTCCTCAACACCGACATGTACAGCCCCAACATCAAGCCTGACCGGAAGAT
GATGCTGGAGGACTTCATCCGAAACCTTCGAGGTGTGGACGATGGCGCTGACATCCCCAGGGAGCTGGTGGTAGGCATCTATGAGAGGAT
ACAGCAGAAGGAGCTCAAGTCCAATGAGGACCACGTCACGTACGTCACCAAGGTGGAGAAGTCCATTGTGGGCATGAAGACAGTGCTGTC
CGTGCCCCACCGCCGCCTGGTGTGCTGCAGCCGGCTCTTCGAGGTGACGGATGTGAACAAGCTGCAGAAGCAGGCAGCGCATCAGAGGGA
GGTGTTCCTCTTCAATGACCTGCTGGTGATTCTCAAACTTTGCCCGAAGAAGAAGAGCTCCTCCACGTACACCTTTTGCAAGTCAGTTGG
CCTGCTGGGCATGCAGTTCCAGCTCTTTGAGAACGAGTATTACTCTCATGGCATCACACTGGTGACCCCGCTCTCGGGCTCCGAGAAGAA
GCAGGTGCTGCATTTCTGTGCCCTGGGCTCGGACGAGATGCAGAAGTTCGTGGAGGACCTGAAGGAGTCCATTGCTGAGGTGACGGAGCT
GGAGCAGATCCGAATAGAGTGGGAGCTGGAGAAGCAGCAGGGAACAAAGACACTCTCCTTCAAGCCCTGCGGAGCCCAGGGGGACCCACA
GTCAAAGCAAGGATCGCCGACAGCCAAAAGGGAAGCCGCGCTCAGGGAGAGGCCGGCGGAGAGCACGGTGGAGGTGTCAATTCACAACAG
GCTTCAAACGTCCCAGCACAACTCCGGGCTGGGGGCCGAGAGGGGAGCGCCGGTGCCGCCGCCAGACCTGCAGCCTAGCCCCCCGAGACA
GCAGACCCCACCACTGCCGCCGCCGCCACCCACGCCCCCGGGCACCCTGGTGCAGTGCCAGCAAATTGTCAAGGTCATTGTCCTGGACAA
GCCCTGCCTGGCCCGCATGGAGCCCCTGCTGAGCCAGGCTCTCTCCTGCTACACCTCGTCGTCCTCTGACTCCTGCGGCTCCACACCCCT
GGGCGGTCCCGGCTCTCCGGTCAAGGTCACCCACCAGCCTCCGCTGCCCCCGCCCCCACCCCCCTACAACCACCCTCACCAGTTCTGTCC
CCCAGGCTCCCTGCTGCACGGGCACCGCTACTCCAGTGGCTCAAGGAGCCTGGTGTAGACTCTGCCCCACCACCCTGCTGTCCTGGGAGG
GCTGGCCACTGGGGGGCCTGGGCTGCCCCTCCACTGCTCCCCATACCCTGGCACGATGCGTTCCTGGTCACTGATCACCATCATTTTGGG
AAGAGAATCCCAATCCCTGGCACCTGGGTTTGCCTCATCCAACCATCCTTCCCTTTCTCAGCTGCACCCCCTCTGCAGATCTGAAGACAC
ACCTCACTCTCCCAGGGCCCTACACAGCCAGACCCGGCGAGGCCTCCTCTTCCCCTGGCCACCACTTTCCCCCATTGGACCATGGACTGA
AGAAAACGAGCTGAGGGTCTAACGAGCTTGCAGGCTTTGAGTCTGTTAGTGCCCGGGGCCTCGGGCCTTGGGCAGCAGCATGAGGCTGGG
CCGGCCGGCAGTGGAGCACTAGACAGAGTGGCTGGCTCGCAGCCCAGAACTAGTGCCTCTGTAGCTGCACTGAGGGGAGGAGGGTTGGTC
CCACCCCTGGAGGGACAGGTGGGAGGAGTGAGGAGGGGGCTTTTTCTGCCACCCCCGCCCCCAAGCCTGAAACTCTCAGGAGTCTACTTC
TTGGTCCCCAGGGACATTGGCTGTCCTGACCATGTCCTTCCCCCTCCTCCCAGGGCCTCTGCTTCCTCAGGAGCTGCCCAGACTCCAGAA
AAGCCTGGAAAAAGGGAGGCGGGAAGGGGAGCACTTTCGGCTTTCTATAGGTCAGTCCAGCAGGGCCACGGGATCGCGAGGTCATGTATC
TGCAAAATGCACCTTTTTAAAGAGTGTCTTAGTTCCCCAGCCCCAGCTAATACCCGGCCAATGCCGTGTACGCACCGGCATGTGCACGCA
AACACGCATGAGAACCAGGCCATTCCTTCCGCTGTGGAAGCAGAACTGGAGACGGGGCAGGAATGTGCCCAGCAGAGATGGGGCTCAGCC
CGAGGCAGGGCTCCCTCCTGCATGAGGCTCGGCCCGAGGCAGGGCTCCCTCCTGCATGAGTCTGTGGCCTCCAGGAGGGACTTGGGTGCA
GATGTAAGCAAGAAAAACCGGGGCTCCAGAGGCATGTGCATTTCCCCTGCGCCCCTCAGCCTTTAAATATTCCCTCCTCCTAGAAGGTTC
TAGACCCCCCCCTTCCAGCAGGGGTGCCCAAGAGTCCCTGGACCCTCAAAATTGCAAAGGAGACCCAAGCGGGGCTCGCTGACCTCCCAG
GGCCCAGCAAGATGGGATAGCCAGCCTTAGGTGGCCCCACGAGCCCAAGCCTGGGGAAGGGCCCCTCCCCAGCCAGACGAGAGGCAGCCA
CCCCAGAGACCACAGGAGCCGTACCATGGCCTGCGCAGTCAGGCCCTATCAGGATGTGTCTGTCCCAAGCCTGGCCAGGCTCCAGTCCTG
TGCCAGTAGCTCACTGCTGTCCTATGTGCAGGTCCCCCAACACTTGGAGCCTGTGGTTAAGGCCTCCTGGGAGAGGCAGTGAGCATGAGT
CAAAGGTGACATGGACTTGAATCTCCCCACCCCGCCCCGCCTGCAGTAGCCGGGCCAGGTAGGAGGCAAGGATCATTCCCTGCTCCCAGA
GGTTCCAGATGACCTAGTTTCGTTTTGTGTGTGTGTGTGTGTGGTCACCCAGACGTCACTGTGATATCACCTAGTGAATCTATTTCTGGC
CCTGTCTTCGTCGGCCCAGTTTCTGTAACTTGCAGCCAATTTGCCCTCTCCCCTGTGGCTGCCAGCCCATCTGCCCCTCTGTGTCCTTGC
TGCCCTGGCCCTCCTCTGTTTTCTGTAACAGATGCTCCAGTCATTGCCTTTCAGAGTGGAGCAGATGACAGATGGGGTGCACGCATTCAG
ACACCTCTGATGCCCTTAGCCAGGGCAGGGATCGTCCTTAAAGTGAAGGCCTGGACAGGAGGAGTCAGGGACTTGGGAGGAGGTGGAGCT
GTGGGGATGGGAGTGGAGGAATCAAAATGAGGGAAGCTGAAAATAGAATGAAAACGATGACTAAGAGGCAGGGAGTGCGAGGTATGGGGG
AATAGGAACTATGAGCTAAATATACTTATGGGGTGGGGGCCGTGGGGGCCAGGGACACTCTCCCAGACAGCCCTGACCCGCCAGGCAGGA
CCCCGTCCCCTGCTCACACAGCTCTTCAAACTTACCAAGGACAGGCAGGACCCCGTCCCCTGCTCACACAGCTCTTCAAGCTTACCAAGG
ACAGGCAGAACCCCGTCCCCTGCTCACACAGCTCTTCAAGCTTACCAAGGACAGGCAGGACCCCGTCCCCTGCTCACACAGCTCTTCAAA
CTTACCAAGTGCCCTCTCCCCTGTTGAGGGCACAGCAACCCCAGGCCCTCCCTCCCACCTCAGCTGAAGCCCCAATCTTCCAAATCGGAA
CCAGCAAGTCTTAGGGCTGGCACGCATCTGGGCCTCTAGCTGAGAACCCGGACTCTCAGGCACCTCAGTGCCCCTGCCCCAGGGCAGAGG
CCCACCCCGTGGGTTGGTGCAGTGGCTGCCCTGGGCTCCACGGGCAGCACAGGGAGTCTGTCCAGGAAGCAGCCCAGCCGGGGTCAGTAT
TCCGTGGAGCCAGTCCTGAGCTGGGAGGGGCATTTAACACCCCTGAGGGCCTGGGGCAGGACACAGCTGGCCCTCCTCATTGTCAGGGGA
AGCAAGTGCCCAACATCTGTAACCTCCCTTCCCTGCTCAGTCCCCAGGCCAAGGTTGGGACCCCTCTCCATCCCTGTCCCCAGAGCCTAG
ACCTCAGGGACCTAGGAAAAGCCTCCTGCTCCCTCCCCACGGCAGCAGACAGGGCAGGGCCTCCAGCCCCCAGAGGGCCGGTGGGGGGTG
CTCTCGGGCCTTCCTGCTCTCCTAAGGTTGCGGGGACAGTAGAGTGCTGAGCCCCAGACCCAGTCACCCCAAGATGGCCCCACTCTATCC
ACTCTCTAGACCTTTGGGAAATCTGGGTCCCTCTCCTGATTTGATCCATTCGGCCCCAACTCCAGAGTCGGGAATGGGAGATGAAACTAG
TTTTCCACCCACTTTTGGACAAGTCCCACCCCTAGATCTGAAGCAAGCTCTACCAGCAGCGTGTCCTGGAAGCCTGCCTGCCTGCCTGCC
CGTCTGCACAGGTGTCTTGATCCAGCCCTGCGTCTTCGAGCCCCTGTGCCACCGGTCCCCACGGCCCGCCAGGAGTCTCTTTGTACCCAC
TAGGCTTCCCTGATGACCATCTGTCTGTCCGTCCCTGTTTTTGCTGTACATAACTCCTGCTGCACCCTCTCCCCGCACACCCGTCACCCA
TGAGAGAGAGAAACCTCTCTAGGGAAAGGCAGGGTGGCTGCACCCAGCAACTAATCCAAATGGCAAATATTTTGTAACAAAATAGCCCAG

>99331_99331_16_WNK1-IQSEC3_WNK1_chr12_863490_ENST00000535572_IQSEC3_chr12_247433_ENST00000538872_length(amino acids)=1183AA_BP=300
MSVLSEASSGSARTRPAAVPCRPLRGRLGPSRPFRSRIRARSPLSSEPTMSGGAAEKQSSTPGSLFLSPPAPAPKNGSSSDSSVGEKLGA
AAADAVTGRTEEYRRRRHTMDKDSRGAAATTTTTEHRFFRRSVICDSNATALELPGLPLSLPQPSIPAAVPQSAPPEPHREETVTATATS
QVAQQPPAAAAPGEQAVAGPAPSTVPSSTSKDRPVSQPSLVGSKEEPPPARSGSGGGSAKEPQEERSQQQDDIEELETKAVGMSNDGRFL
KFDIEIGRGSFKTVYKGLDTETTVEVAWCELQIEMLEHKYGGHLVSRRAACTIQTAFRQYQLSKNFEKIRNSLLESRLPRRISLRKVRSP
TAESLAAEKALMEGYGLVGLPLVRSPSLPPTFAGTLTELEDSFTEQVQSLAKSIDDALSTWSLKTMCSLRESGAYQLHQALQAAAGPPGL
EAEGRAPESAGPGPGDDAAETPGLPPAHSGTLMMAFRDVTVQIANQNISVSSSTALSVANCLGAQTVQAPAEPAAGKAEQGETSGREAPE
APAVGREDASAEDSCAEAAASGAADGATAPKTEEEEEEEETAEVGRGAEAEAGDLEQLSSSSTSTKSAKSGSEASASASKDALQAMILSL
PRYHCENPASCKSPTLSTDTLRKRLYRIGLNLFNINPDKGIQFLISRGFIPDTPIGVAHFLLQRKGLSRQMIGEFLGNSKKQFNRDVLDC
VVDEMDFSSMELDEALRKFQAHIRVQGEAQKVERLIEAFSQRYCMCNPEVVQQFHNPDTIFILAFAIILLNTDMYSPNIKPDRKMMLEDF
IRNLRGVDDGADIPRELVVGIYERIQQKELKSNEDHVTYVTKVEKSIVGMKTVLSVPHRRLVCCSRLFEVTDVNKLQKQAAHQREVFLFN
DLLVILKLCPKKKSSSTYTFCKSVGLLGMQFQLFENEYYSHGITLVTPLSGSEKKQVLHFCALGSDEMQKFVEDLKESIAEVTELEQIRI
EWELEKQQGTKTLSFKPCGAQGDPQSKQGSPTAKREAALRERPAESTVEVSIHNRLQTSQHNSGLGAERGAPVPPPDLQPSPPRQQTPPL
PPPPPTPPGTLVQCQQIVKVIVLDKPCLARMEPLLSQALSCYTSSSSDSCGSTPLGGPGSPVKVTHQPPLPPPPPPYNHPHQFCPPGSLL

--------------------------------------------------------------
>99331_99331_17_WNK1-IQSEC3_WNK1_chr12_863490_ENST00000537687_IQSEC3_chr12_247432_ENST00000326261_length(transcript)=7362nt_BP=1402nt
CCGGCCCTTCGCCTCTGGGCGATGGGCGACCTGTGAGGCCGGTCCCCATCGCTGGGGGCGCGTGTGGGAGGAGGCGGCCGCCCGAGTGAC
CGGGAGCCGGGCCGCGGCCTTCCCTCGCCCGCCTCGGCCCCTCCCACTCCTCTGCCCCGGGGCCGCCACCGCCCGGGCGTCGGACCTGGT
CCCGTGCTCGCGGTGCCGCCGCCCTCTGGGCCTAGCCCGCCCAGCTCGGCGAGCGGCGGCAGTGGGAGCCGCGTCCGCCGCATCCGCCTC
GACTCGGTGCCGGCCCCTGGCCCTCCCCTCATGACTGCGGCGCCTCTGCTGCCACCGCCCGCCCGGCCGCCGCTCGCCGCAGGATGGATG
CGGACCGTGCGGCGCTAACCCCCGTGGCTCAGCTCCCGAATCGCCCGCCTTCGAGCCCTCCTCGTGAGCCGCAGCAGCCTCGGTGCCAGC
CCCCGCCGCAGCTGGGCCCAGCGGTCCGCCTGTCCCTCGTTGCGGCTTGTCGGTGCTGAGTGAGGCGTCGTCCGGGTCGGCGCGAACCCG
CCCGGCCGCGGTTCCCTGCAGACCTCTGCGCGGGCGGCTCGGCCCTTCACGCCCTTTTCGTTCACGAATCCGAGCCCGCTCGCCTCTCTC
CAGCGAACCGACCATGTCTGGCGGCGCCGCAGAGAAGCAGAGCAGCACTCCCGGTTCCCTGTTCCTCTCGCCGCCGGCTCCTGCCCCCAA
GAATGGCTCCAGCTCCGATTCCTCCGTGGGGGAGAAACTGGGAGCCGCGGCCGCCGACGCTGTGACCGGCAGGACCGAGGAGTACAGGCG
CCGCCGCCACACTATGGACAAGGACAGCCGTGGGGCGGCCGCGACCACTACCACCACTGAGCACCGCTTCTTCCGCCGGAGCGTCATCTG
TGACTCCAATGCCACTGCACTGGAGCTTCCCGGCCTTCCTCTTTCCCTGCCCCAGCCCAGCATCCCCGCGGCTGTCCCGCAGAGTGCTCC
ACCGGAGCCCCACCGGGAAGAGACCGTGACCGCCACCGCCACTTCCCAGGTAGCCCAGCAGCCTCCAGCCGCTGCCGCCCCTGGGGAACA
GGCCGTCGCGGGCCCTGCCCCCTCGACTGTCCCCAGCAGTACCAGCAAAGACCGCCCAGTGTCCCAGCCTAGCCTTGTGGGGAGCAAAGA
GGAGCCGCCGCCGGCGAGAAGTGGCAGCGGCGGCGGCAGCGCCAAGGAGCCACAGGAGGAACGGAGCCAGCAGCAGGATGATATCGAAGA
GCTGGAGACCAAGGCCGTGGGAATGTCTAACGATGGCCGCTTTCTCAAGTTTGACATCGAAATCGGCAGAGGCTCCTTTAAGACGGTCTA
CAAAGGTCTGGACACTGAAACCACCGTGGAAGTCGCCTGGTGTGAACTGCAGATTGAAATGCTAGAACATAAGTACGGCGGTCACCTGGT
GTCCCGGCGCGCCGCTTGCACCATCCAAACCGCCTTCCGCCAATACCAGCTCAGCAAGAACTTCGAGAAAATCCGCAACTCGCTTCTGGA
GAGCCGCCTGCCACGGCGGATCTCCCTGCGCAAGGTGCGGTCACCCACGGCCGAGAGCCTGGCGGCCGAGAAAGCGCTCATGGAGGGCTA
CGGCCTCGTGGGGCTGCCGCTGGTGCGCTCGCCCTCCCTGCCGCCCACCTTCGCAGGCACCCTCACCGAGCTGGAGGACTCCTTCACCGA
GCAGGTGCAATCCCTGGCCAAGTCCATCGACGACGCGCTCAGCACGTGGAGCCTCAAGACCATGTGCTCCCTGCGGGAGAGTGGCGCTTA
CCAGCTCCACCAGGCCCTGCAGGCGGCCGCGGGGCCCCCAGGCCTGGAGGCCGAGGGGCGGGCGCCGGAGAGCGCGGGCCCCGGGCCCGG
GGATGACGCCGCGGAGACCCCCGGCCTGCCCCCGGCCCACAGCGGGACCCTCATGATGGCTTTCCGGGACGTCACGGTGCAGATCGCCAA
CCAGAACATATCCGTCTCCTCCTCCACGGCTCTGTCGGTGGCCAACTGCCTGGGCGCTCAGACGGTCCAGGCCCCCGCAGAGCCCGCGGC
GGGCAAGGCCGAGCAGGGCGAGACCTCTGGGCGGGAGGCCCCGGAAGCCCCCGCCGTGGGCCGGGAGGACGCGTCAGCCGAGGACTCATG
CGCAGAGGCTGCGGCTAGTGGGGCGGCGGATGGGGCCACAGCCCCCAAAACAGAGGAGGAAGAGGAGGAGGAGGAGACGGCGGAGGTGGG
GAGAGGGGCCGAGGCCGAGGCAGGCGACTTGGAGCAGCTGAGCAGCAGCAGCACGTCCACCAAGTCCGCCAAGTCAGGCTCGGAGGCGTC
GGCCTCCGCCTCCAAGGACGCCCTGCAGGCCATGATCCTGAGCCTGCCGCGCTACCACTGCGAGAACCCAGCCAGCTGCAAGTCGCCCAC
GCTCTCCACCGACACCCTGCGCAAGCGGCTCTACCGCATCGGCCTCAACCTCTTCAACATAAACCCCGACAAGGGCATCCAGTTCCTGAT
CTCACGCGGCTTCATCCCGGACACCCCCATCGGTGTGGCCCATTTCCTCCTCCAGCGAAAGGGCCTCAGCCGCCAGATGATTGGAGAGTT
CCTGGGCAACAGCAAGAAGCAGTTCAACCGCGACGTGCTGGACTGCGTGGTGGACGAGATGGACTTCTCCAGCATGGAGCTGGACGAGGC
CCTGCGCAAGTTCCAGGCACACATCCGTGTGCAGGGGGAGGCTCAGAAGGTGGAGCGGCTCATTGAGGCCTTCAGCCAGCGCTACTGCAT
GTGCAACCCCGAAGTGGTTCAGCAGTTCCACAACCCCGACACCATCTTCATCCTCGCCTTCGCCATCATCCTCCTCAACACCGACATGTA
CAGCCCCAACATCAAGCCTGACCGGAAGATGATGCTGGAGGACTTCATCCGAAACCTTCGAGGTGTGGACGATGGCGCTGACATCCCCAG
GGAGCTGGTGGTAGGCATCTATGAGAGGATACAGCAGAAGGAGCTCAAGTCCAATGAGGACCACGTCACGTACGTCACCAAGGTGGAGAA
GTCCATTGTGGGCATGAAGACAGTGCTGTCCGTGCCCCACCGCCGCCTGGTGTGCTGCAGCCGGCTCTTCGAGGTGACGGATGTGAACAA
GCTGCAGAAGCAGGCAGCGCATCAGAGGGAGGTGTTCCTCTTCAATGACCTGCTGGTGATTCTCAAACTTTGCCCGAAGAAGAAGAGCTC
CTCCACGTACACCTTTTGCAAGTCAGTTGGCCTGCTGGGCATGCAGTTCCAGCTCTTTGAGAACGAGTATTACTCTCATGGCATCACACT
GGTGACCCCGCTCTCGGGCTCCGAGAAGAAGCAGGTGCTGCATTTCTGTGCCCTGGGCTCGGACGAGATGCAGAAGTTCGTGGAGGACCT
GAAGGAGTCCATTGCTGAGGTGACGGAGCTGGAGCAGATCCGAATAGAGTGGGAGCTGGAGAAGCAGCAGGGAACAAAGACACTCTCCTT
CAAGCCCTGCGGAGCCCAGGGGGACCCACAGTCAAAGCAAGGATCGCCGACAGCCAAAAGGGAAGCCGCGCTCAGGGAGAGGCCGGCGGA
GAGCACGGTGGAGGTGTCAATTCACAACAGGCTTCAAACGTCCCAGCACAACTCCGGGCTGGGGGCCGAGAGGGGAGCGCCGGTGCCGCC
GCCAGACCTGCAGCCTAGCCCCCCGAGACAGCAGACCCCACCACTGCCGCCGCCGCCACCCACGCCCCCGGGCACCCTGGTGCAGTGCCA
GCAAATTGTCAAGGTCATTGTCCTGGACAAGCCCTGCCTGGCCCGCATGGAGCCCCTGCTGAGCCAGGCTCTCTCCTGCTACACCTCGTC
GTCCTCTGACTCCTGCGGCTCCACACCCCTGGGCGGTCCCGGCTCTCCGGTCAAGGTCACCCACCAGCCTCCGCTGCCCCCGCCCCCACC
CCCCTACAACCACCCTCACCAGTTCTGTCCCCCAGGCTCCCTGCTGCACGGGCACCGCTACTCCAGTGGCTCAAGGAGCCTGGTGTAGAC
TCTGCCCCACCACCCTGCTGTCCTGGGAGGGCTGGCCACTGGGGGGCCTGGGCTGCCCCTCCACTGCTCCCCATACCCTGGCACGATGCG
TTCCTGGTCACTGATCACCATCATTTTGGGAAGAGAATCCCAATCCCTGGCACCTGGGTTTGCCTCATCCAACCATCCTTCCCTTTCTCA
GCTGCACCCCCTCTGCAGATCTGAAGACACACCTCACTCTCCCAGGGCCCTACACAGCCAGACCCGGCGAGGCCTCCTCTTCCCCTGGCC
ACCACTTTCCCCCATTGGACCATGGACTGAAGAAAACGAGCTGAGGGTCTAACGAGCTTGCAGGCTTTGAGTCTGTTAGTGCCCGGGGCC
TCGGGCCTTGGGCAGCAGCATGAGGCTGGGCCGGCCGGCAGTGGAGCACTAGACAGAGTGGCTGGCTCGCAGCCCAGAACTAGTGCCTCT
GTAGCTGCACTGAGGGGAGGAGGGTTGGTCCCACCCCTGGAGGGACAGGTGGGAGGAGTGAGGAGGGGGCTTTTTCTGCCACCCCCGCCC
CCAAGCCTGAAACTCTCAGGAGTCTACTTCTTGGTCCCCAGGGACATTGGCTGTCCTGACCATGTCCTTCCCCCTCCTCCCAGGGCCTCT
GCTTCCTCAGGAGCTGCCCAGACTCCAGAAAAGCCTGGAAAAAGGGAGGCGGGAAGGGGAGCACTTTCGGCTTTCTATAGGTCAGTCCAG
CAGGGCCACGGGATCGCGAGGTCATGTATCTGCAAAATGCACCTTTTTAAAGAGTGTCTTAGTTCCCCAGCCCCAGCTAATACCCGGCCA
ATGCCGTGTACGCACCGGCATGTGCACGCAAACACGCATGAGAACCAGGCCATTCCTTCCGCTGTGGAAGCAGAACTGGAGACGGGGCAG
GAATGTGCCCAGCAGAGATGGGGCTCAGCCCGAGGCAGGGCTCCCTCCTGCATGAGGCTCGGCCCGAGGCAGGGCTCCCTCCTGCATGAG
TCTGTGGCCTCCAGGAGGGACTTGGGTGCAGATGTAAGCAAGAAAAACCGGGGCTCCAGAGGCATGTGCATTTCCCCTGCGCCCCTCAGC
CTTTAAATATTCCCTCCTCCTAGAAGGTTCTAGACCCCCCCCTTCCAGCAGGGGTGCCCAAGAGTCCCTGGACCCTCAAAATTGCAAAGG
AGACCCAAGCGGGGCTCGCTGACCTCCCAGGGCCCAGCAAGATGGGATAGCCAGCCTTAGGTGGCCCCACGAGCCCAAGCCTGGGGAAGG
GCCCCTCCCCAGCCAGACGAGAGGCAGCCACCCCAGAGACCACAGGAGCCGTACCATGGCCTGCGCAGTCAGGCCCTATCAGGATGTGTC
TGTCCCAAGCCTGGCCAGGCTCCAGTCCTGTGCCAGTAGCTCACTGCTGTCCTATGTGCAGGTCCCCCAACACTTGGAGCCTGTGGTTAA
GGCCTCCTGGGAGAGGCAGTGAGCATGAGTCAAAGGTGACATGGACTTGAATCTCCCCACCCCGCCCCGCCTGCAGTAGCCGGGCCAGGT
AGGAGGCAAGGATCATTCCCTGCTCCCAGAGGTTCCAGATGACCTAGTTTCGTTTTGTGTGTGTGTGTGTGTGGTCACCCAGACGTCACT
GTGATATCACCTAGTGAATCTATTTCTGGCCCTGTCTTCGTCGGCCCAGTTTCTGTAACTTGCAGCCAATTTGCCCTCTCCCCTGTGGCT
GCCAGCCCATCTGCCCCTCTGTGTCCTTGCTGCCCTGGCCCTCCTCTGTTTTCTGTAACAGATGCTCCAGTCATTGCCTTTCAGAGTGGA
GCAGATGACAGATGGGGTGCACGCATTCAGACACCTCTGATGCCCTTAGCCAGGGCAGGGATCGTCCTTAAAGTGAAGGCCTGGACAGGA
GGAGTCAGGGACTTGGGAGGAGGTGGAGCTGTGGGGATGGGAGTGGAGGAATCAAAATGAGGGAAGCTGAAAATAGAATGAAAACGATGA
CTAAGAGGCAGGGAGTGCGAGGTATGGGGGAATAGGAACTATGAGCTAAATATACTTATGGGGTGGGGGCCGTGGGGGCCAGGGACACTC
TCCCAGACAGCCCTGACCCGCCAGGCAGGACCCCGTCCCCTGCTCACACAGCTCTTCAAACTTACCAAGGACAGGCAGGACCCCGTCCCC
TGCTCACACAGCTCTTCAAGCTTACCAAGTCCCCTGTTGAGGGCACAGCAACCCCAGGCCCTCCCTCCCACCTCAGCTGAAGCCCCAATC
TTCCAAATCGGAACCAGCAAGTCTTAGGGCTGGCACGCATCTGGGCCTCTAGCTGAGAACCCGGACTCTCAGGCACCTCAGTGCCCCTGC
CCCAGGGCAGAGGCCCACCCCGTGGGTTGGTGCAGTGGCTGCCCTGGGCTCCACGGGCAGCACAGGGAGTCTGTCCAGGAAGCAGCCCAG
CCGGGGTCAGTATTCCGTGGAGCCAGTCCTGAGCTGGGAGGGGCATTTAACACCCCTGAGGGCCTGGGGCAGGACACAGCTGGCCCTCCT
CATTGTCAGGGGAAGCAAGTGCCCAACATCTGTAACCTCCCTTCCCTGCTCAGTCCCCAGGCCAAGGTTGGGACCCCTCTCCATCCCTGT
CCCCAGAGCCTAGACCTCAGGGACCTAGGAAAAGCCTCCTGCTCCCTCCCCACGGCAGCAGACAGGGCAGGGCCTCCAGCCCCCAGAGGG
CCGGTGGGGGGTGCTCTCGGGCCTTCCTGCTCTCCTAAGGTTGCGGGGACAGTAGAGTGCTGAGCCCCAGACCCAGTCACCCCAAGATGG
CCCCACTCTATCCACTCTCTAGACCTTTGGGAAATCTGGGTCCCTCTCCTGATTTGATCCATTCGGCCCCAACTCCAGAGTCGGGAATGG
GAGATGAAACTAGTTTTCCACCCACTTTTGGACAAGTCCCACCCCTAGATCTGAAGCAAGCTCTACCAGCAGCGTGTCCTGGAAGCCTGC
CTGCCTGCCTGCCCGTCTGCACAGGTGTCTTGATCCAGCCCTGCGTCTTCGAGCCCCTGTGCCACCGGTCCCCACGGCCCGCCAGGAGTC
TCTTTGTACCCACTAGGCTTCCCTGATGACCATCTGTCTGTCCGTCCCTGTTTTTGCTGTACATAACTCCTGCTGCACCCTCTCCCCGCA
CACCCGTCACCCATGAGAGAGAGAAACCTCTCTAGGGAAAGGCAGGGTGGCTGCACCCAGCAACTAATCCAAATGGCAAATATTTTGTAA

>99331_99331_17_WNK1-IQSEC3_WNK1_chr12_863490_ENST00000537687_IQSEC3_chr12_247432_ENST00000326261_length(amino acids)=1183AA_BP=300
MSVLSEASSGSARTRPAAVPCRPLRGRLGPSRPFRSRIRARSPLSSEPTMSGGAAEKQSSTPGSLFLSPPAPAPKNGSSSDSSVGEKLGA
AAADAVTGRTEEYRRRRHTMDKDSRGAAATTTTTEHRFFRRSVICDSNATALELPGLPLSLPQPSIPAAVPQSAPPEPHREETVTATATS
QVAQQPPAAAAPGEQAVAGPAPSTVPSSTSKDRPVSQPSLVGSKEEPPPARSGSGGGSAKEPQEERSQQQDDIEELETKAVGMSNDGRFL
KFDIEIGRGSFKTVYKGLDTETTVEVAWCELQIEMLEHKYGGHLVSRRAACTIQTAFRQYQLSKNFEKIRNSLLESRLPRRISLRKVRSP
TAESLAAEKALMEGYGLVGLPLVRSPSLPPTFAGTLTELEDSFTEQVQSLAKSIDDALSTWSLKTMCSLRESGAYQLHQALQAAAGPPGL
EAEGRAPESAGPGPGDDAAETPGLPPAHSGTLMMAFRDVTVQIANQNISVSSSTALSVANCLGAQTVQAPAEPAAGKAEQGETSGREAPE
APAVGREDASAEDSCAEAAASGAADGATAPKTEEEEEEEETAEVGRGAEAEAGDLEQLSSSSTSTKSAKSGSEASASASKDALQAMILSL
PRYHCENPASCKSPTLSTDTLRKRLYRIGLNLFNINPDKGIQFLISRGFIPDTPIGVAHFLLQRKGLSRQMIGEFLGNSKKQFNRDVLDC
VVDEMDFSSMELDEALRKFQAHIRVQGEAQKVERLIEAFSQRYCMCNPEVVQQFHNPDTIFILAFAIILLNTDMYSPNIKPDRKMMLEDF
IRNLRGVDDGADIPRELVVGIYERIQQKELKSNEDHVTYVTKVEKSIVGMKTVLSVPHRRLVCCSRLFEVTDVNKLQKQAAHQREVFLFN
DLLVILKLCPKKKSSSTYTFCKSVGLLGMQFQLFENEYYSHGITLVTPLSGSEKKQVLHFCALGSDEMQKFVEDLKESIAEVTELEQIRI
EWELEKQQGTKTLSFKPCGAQGDPQSKQGSPTAKREAALRERPAESTVEVSIHNRLQTSQHNSGLGAERGAPVPPPDLQPSPPRQQTPPL
PPPPPTPPGTLVQCQQIVKVIVLDKPCLARMEPLLSQALSCYTSSSSDSCGSTPLGGPGSPVKVTHQPPLPPPPPPYNHPHQFCPPGSLL

--------------------------------------------------------------
>99331_99331_18_WNK1-IQSEC3_WNK1_chr12_863490_ENST00000537687_IQSEC3_chr12_247432_ENST00000538872_length(transcript)=7475nt_BP=1402nt
CCGGCCCTTCGCCTCTGGGCGATGGGCGACCTGTGAGGCCGGTCCCCATCGCTGGGGGCGCGTGTGGGAGGAGGCGGCCGCCCGAGTGAC
CGGGAGCCGGGCCGCGGCCTTCCCTCGCCCGCCTCGGCCCCTCCCACTCCTCTGCCCCGGGGCCGCCACCGCCCGGGCGTCGGACCTGGT
CCCGTGCTCGCGGTGCCGCCGCCCTCTGGGCCTAGCCCGCCCAGCTCGGCGAGCGGCGGCAGTGGGAGCCGCGTCCGCCGCATCCGCCTC
GACTCGGTGCCGGCCCCTGGCCCTCCCCTCATGACTGCGGCGCCTCTGCTGCCACCGCCCGCCCGGCCGCCGCTCGCCGCAGGATGGATG
CGGACCGTGCGGCGCTAACCCCCGTGGCTCAGCTCCCGAATCGCCCGCCTTCGAGCCCTCCTCGTGAGCCGCAGCAGCCTCGGTGCCAGC
CCCCGCCGCAGCTGGGCCCAGCGGTCCGCCTGTCCCTCGTTGCGGCTTGTCGGTGCTGAGTGAGGCGTCGTCCGGGTCGGCGCGAACCCG
CCCGGCCGCGGTTCCCTGCAGACCTCTGCGCGGGCGGCTCGGCCCTTCACGCCCTTTTCGTTCACGAATCCGAGCCCGCTCGCCTCTCTC
CAGCGAACCGACCATGTCTGGCGGCGCCGCAGAGAAGCAGAGCAGCACTCCCGGTTCCCTGTTCCTCTCGCCGCCGGCTCCTGCCCCCAA
GAATGGCTCCAGCTCCGATTCCTCCGTGGGGGAGAAACTGGGAGCCGCGGCCGCCGACGCTGTGACCGGCAGGACCGAGGAGTACAGGCG
CCGCCGCCACACTATGGACAAGGACAGCCGTGGGGCGGCCGCGACCACTACCACCACTGAGCACCGCTTCTTCCGCCGGAGCGTCATCTG
TGACTCCAATGCCACTGCACTGGAGCTTCCCGGCCTTCCTCTTTCCCTGCCCCAGCCCAGCATCCCCGCGGCTGTCCCGCAGAGTGCTCC
ACCGGAGCCCCACCGGGAAGAGACCGTGACCGCCACCGCCACTTCCCAGGTAGCCCAGCAGCCTCCAGCCGCTGCCGCCCCTGGGGAACA
GGCCGTCGCGGGCCCTGCCCCCTCGACTGTCCCCAGCAGTACCAGCAAAGACCGCCCAGTGTCCCAGCCTAGCCTTGTGGGGAGCAAAGA
GGAGCCGCCGCCGGCGAGAAGTGGCAGCGGCGGCGGCAGCGCCAAGGAGCCACAGGAGGAACGGAGCCAGCAGCAGGATGATATCGAAGA
GCTGGAGACCAAGGCCGTGGGAATGTCTAACGATGGCCGCTTTCTCAAGTTTGACATCGAAATCGGCAGAGGCTCCTTTAAGACGGTCTA
CAAAGGTCTGGACACTGAAACCACCGTGGAAGTCGCCTGGTGTGAACTGCAGATTGAAATGCTAGAACATAAGTACGGCGGTCACCTGGT
GTCCCGGCGCGCCGCTTGCACCATCCAAACCGCCTTCCGCCAATACCAGCTCAGCAAGAACTTCGAGAAAATCCGCAACTCGCTTCTGGA
GAGCCGCCTGCCACGGCGGATCTCCCTGCGCAAGGTGCGGTCACCCACGGCCGAGAGCCTGGCGGCCGAGAAAGCGCTCATGGAGGGCTA
CGGCCTCGTGGGGCTGCCGCTGGTGCGCTCGCCCTCCCTGCCGCCCACCTTCGCAGGCACCCTCACCGAGCTGGAGGACTCCTTCACCGA
GCAGGTGCAATCCCTGGCCAAGTCCATCGACGACGCGCTCAGCACGTGGAGCCTCAAGACCATGTGCTCCCTGCGGGAGAGTGGCGCTTA
CCAGCTCCACCAGGCCCTGCAGGCGGCCGCGGGGCCCCCAGGCCTGGAGGCCGAGGGGCGGGCGCCGGAGAGCGCGGGCCCCGGGCCCGG
GGATGACGCCGCGGAGACCCCCGGCCTGCCCCCGGCCCACAGCGGGACCCTCATGATGGCTTTCCGGGACGTCACGGTGCAGATCGCCAA
CCAGAACATATCCGTCTCCTCCTCCACGGCTCTGTCGGTGGCCAACTGCCTGGGCGCTCAGACGGTCCAGGCCCCCGCAGAGCCCGCGGC
GGGCAAGGCCGAGCAGGGCGAGACCTCTGGGCGGGAGGCCCCGGAAGCCCCCGCCGTGGGCCGGGAGGACGCGTCAGCCGAGGACTCATG
CGCAGAGGCTGCGGCTAGTGGGGCGGCGGATGGGGCCACAGCCCCCAAAACAGAGGAGGAAGAGGAGGAGGAGGAGACGGCGGAGGTGGG
GAGAGGGGCCGAGGCCGAGGCAGGCGACTTGGAGCAGCTGAGCAGCAGCAGCACGTCCACCAAGTCCGCCAAGTCAGGCTCGGAGGCGTC
GGCCTCCGCCTCCAAGGACGCCCTGCAGGCCATGATCCTGAGCCTGCCGCGCTACCACTGCGAGAACCCAGCCAGCTGCAAGTCGCCCAC
GCTCTCCACCGACACCCTGCGCAAGCGGCTCTACCGCATCGGCCTCAACCTCTTCAACATAAACCCCGACAAGGGCATCCAGTTCCTGAT
CTCACGCGGCTTCATCCCGGACACCCCCATCGGTGTGGCCCATTTCCTCCTCCAGCGAAAGGGCCTCAGCCGCCAGATGATTGGAGAGTT
CCTGGGCAACAGCAAGAAGCAGTTCAACCGCGACGTGCTGGACTGCGTGGTGGACGAGATGGACTTCTCCAGCATGGAGCTGGACGAGGC
CCTGCGCAAGTTCCAGGCACACATCCGTGTGCAGGGGGAGGCTCAGAAGGTGGAGCGGCTCATTGAGGCCTTCAGCCAGCGCTACTGCAT
GTGCAACCCCGAAGTGGTTCAGCAGTTCCACAACCCCGACACCATCTTCATCCTCGCCTTCGCCATCATCCTCCTCAACACCGACATGTA
CAGCCCCAACATCAAGCCTGACCGGAAGATGATGCTGGAGGACTTCATCCGAAACCTTCGAGGTGTGGACGATGGCGCTGACATCCCCAG
GGAGCTGGTGGTAGGCATCTATGAGAGGATACAGCAGAAGGAGCTCAAGTCCAATGAGGACCACGTCACGTACGTCACCAAGGTGGAGAA
GTCCATTGTGGGCATGAAGACAGTGCTGTCCGTGCCCCACCGCCGCCTGGTGTGCTGCAGCCGGCTCTTCGAGGTGACGGATGTGAACAA
GCTGCAGAAGCAGGCAGCGCATCAGAGGGAGGTGTTCCTCTTCAATGACCTGCTGGTGATTCTCAAACTTTGCCCGAAGAAGAAGAGCTC
CTCCACGTACACCTTTTGCAAGTCAGTTGGCCTGCTGGGCATGCAGTTCCAGCTCTTTGAGAACGAGTATTACTCTCATGGCATCACACT
GGTGACCCCGCTCTCGGGCTCCGAGAAGAAGCAGGTGCTGCATTTCTGTGCCCTGGGCTCGGACGAGATGCAGAAGTTCGTGGAGGACCT
GAAGGAGTCCATTGCTGAGGTGACGGAGCTGGAGCAGATCCGAATAGAGTGGGAGCTGGAGAAGCAGCAGGGAACAAAGACACTCTCCTT
CAAGCCCTGCGGAGCCCAGGGGGACCCACAGTCAAAGCAAGGATCGCCGACAGCCAAAAGGGAAGCCGCGCTCAGGGAGAGGCCGGCGGA
GAGCACGGTGGAGGTGTCAATTCACAACAGGCTTCAAACGTCCCAGCACAACTCCGGGCTGGGGGCCGAGAGGGGAGCGCCGGTGCCGCC
GCCAGACCTGCAGCCTAGCCCCCCGAGACAGCAGACCCCACCACTGCCGCCGCCGCCACCCACGCCCCCGGGCACCCTGGTGCAGTGCCA
GCAAATTGTCAAGGTCATTGTCCTGGACAAGCCCTGCCTGGCCCGCATGGAGCCCCTGCTGAGCCAGGCTCTCTCCTGCTACACCTCGTC
GTCCTCTGACTCCTGCGGCTCCACACCCCTGGGCGGTCCCGGCTCTCCGGTCAAGGTCACCCACCAGCCTCCGCTGCCCCCGCCCCCACC
CCCCTACAACCACCCTCACCAGTTCTGTCCCCCAGGCTCCCTGCTGCACGGGCACCGCTACTCCAGTGGCTCAAGGAGCCTGGTGTAGAC
TCTGCCCCACCACCCTGCTGTCCTGGGAGGGCTGGCCACTGGGGGGCCTGGGCTGCCCCTCCACTGCTCCCCATACCCTGGCACGATGCG
TTCCTGGTCACTGATCACCATCATTTTGGGAAGAGAATCCCAATCCCTGGCACCTGGGTTTGCCTCATCCAACCATCCTTCCCTTTCTCA
GCTGCACCCCCTCTGCAGATCTGAAGACACACCTCACTCTCCCAGGGCCCTACACAGCCAGACCCGGCGAGGCCTCCTCTTCCCCTGGCC
ACCACTTTCCCCCATTGGACCATGGACTGAAGAAAACGAGCTGAGGGTCTAACGAGCTTGCAGGCTTTGAGTCTGTTAGTGCCCGGGGCC
TCGGGCCTTGGGCAGCAGCATGAGGCTGGGCCGGCCGGCAGTGGAGCACTAGACAGAGTGGCTGGCTCGCAGCCCAGAACTAGTGCCTCT
GTAGCTGCACTGAGGGGAGGAGGGTTGGTCCCACCCCTGGAGGGACAGGTGGGAGGAGTGAGGAGGGGGCTTTTTCTGCCACCCCCGCCC
CCAAGCCTGAAACTCTCAGGAGTCTACTTCTTGGTCCCCAGGGACATTGGCTGTCCTGACCATGTCCTTCCCCCTCCTCCCAGGGCCTCT
GCTTCCTCAGGAGCTGCCCAGACTCCAGAAAAGCCTGGAAAAAGGGAGGCGGGAAGGGGAGCACTTTCGGCTTTCTATAGGTCAGTCCAG
CAGGGCCACGGGATCGCGAGGTCATGTATCTGCAAAATGCACCTTTTTAAAGAGTGTCTTAGTTCCCCAGCCCCAGCTAATACCCGGCCA
ATGCCGTGTACGCACCGGCATGTGCACGCAAACACGCATGAGAACCAGGCCATTCCTTCCGCTGTGGAAGCAGAACTGGAGACGGGGCAG
GAATGTGCCCAGCAGAGATGGGGCTCAGCCCGAGGCAGGGCTCCCTCCTGCATGAGGCTCGGCCCGAGGCAGGGCTCCCTCCTGCATGAG
TCTGTGGCCTCCAGGAGGGACTTGGGTGCAGATGTAAGCAAGAAAAACCGGGGCTCCAGAGGCATGTGCATTTCCCCTGCGCCCCTCAGC
CTTTAAATATTCCCTCCTCCTAGAAGGTTCTAGACCCCCCCCTTCCAGCAGGGGTGCCCAAGAGTCCCTGGACCCTCAAAATTGCAAAGG
AGACCCAAGCGGGGCTCGCTGACCTCCCAGGGCCCAGCAAGATGGGATAGCCAGCCTTAGGTGGCCCCACGAGCCCAAGCCTGGGGAAGG
GCCCCTCCCCAGCCAGACGAGAGGCAGCCACCCCAGAGACCACAGGAGCCGTACCATGGCCTGCGCAGTCAGGCCCTATCAGGATGTGTC
TGTCCCAAGCCTGGCCAGGCTCCAGTCCTGTGCCAGTAGCTCACTGCTGTCCTATGTGCAGGTCCCCCAACACTTGGAGCCTGTGGTTAA
GGCCTCCTGGGAGAGGCAGTGAGCATGAGTCAAAGGTGACATGGACTTGAATCTCCCCACCCCGCCCCGCCTGCAGTAGCCGGGCCAGGT
AGGAGGCAAGGATCATTCCCTGCTCCCAGAGGTTCCAGATGACCTAGTTTCGTTTTGTGTGTGTGTGTGTGTGGTCACCCAGACGTCACT
GTGATATCACCTAGTGAATCTATTTCTGGCCCTGTCTTCGTCGGCCCAGTTTCTGTAACTTGCAGCCAATTTGCCCTCTCCCCTGTGGCT
GCCAGCCCATCTGCCCCTCTGTGTCCTTGCTGCCCTGGCCCTCCTCTGTTTTCTGTAACAGATGCTCCAGTCATTGCCTTTCAGAGTGGA
GCAGATGACAGATGGGGTGCACGCATTCAGACACCTCTGATGCCCTTAGCCAGGGCAGGGATCGTCCTTAAAGTGAAGGCCTGGACAGGA
GGAGTCAGGGACTTGGGAGGAGGTGGAGCTGTGGGGATGGGAGTGGAGGAATCAAAATGAGGGAAGCTGAAAATAGAATGAAAACGATGA
CTAAGAGGCAGGGAGTGCGAGGTATGGGGGAATAGGAACTATGAGCTAAATATACTTATGGGGTGGGGGCCGTGGGGGCCAGGGACACTC
TCCCAGACAGCCCTGACCCGCCAGGCAGGACCCCGTCCCCTGCTCACACAGCTCTTCAAACTTACCAAGGACAGGCAGGACCCCGTCCCC
TGCTCACACAGCTCTTCAAGCTTACCAAGGACAGGCAGAACCCCGTCCCCTGCTCACACAGCTCTTCAAGCTTACCAAGGACAGGCAGGA
CCCCGTCCCCTGCTCACACAGCTCTTCAAACTTACCAAGTGCCCTCTCCCCTGTTGAGGGCACAGCAACCCCAGGCCCTCCCTCCCACCT
CAGCTGAAGCCCCAATCTTCCAAATCGGAACCAGCAAGTCTTAGGGCTGGCACGCATCTGGGCCTCTAGCTGAGAACCCGGACTCTCAGG
CACCTCAGTGCCCCTGCCCCAGGGCAGAGGCCCACCCCGTGGGTTGGTGCAGTGGCTGCCCTGGGCTCCACGGGCAGCACAGGGAGTCTG
TCCAGGAAGCAGCCCAGCCGGGGTCAGTATTCCGTGGAGCCAGTCCTGAGCTGGGAGGGGCATTTAACACCCCTGAGGGCCTGGGGCAGG
ACACAGCTGGCCCTCCTCATTGTCAGGGGAAGCAAGTGCCCAACATCTGTAACCTCCCTTCCCTGCTCAGTCCCCAGGCCAAGGTTGGGA
CCCCTCTCCATCCCTGTCCCCAGAGCCTAGACCTCAGGGACCTAGGAAAAGCCTCCTGCTCCCTCCCCACGGCAGCAGACAGGGCAGGGC
CTCCAGCCCCCAGAGGGCCGGTGGGGGGTGCTCTCGGGCCTTCCTGCTCTCCTAAGGTTGCGGGGACAGTAGAGTGCTGAGCCCCAGACC
CAGTCACCCCAAGATGGCCCCACTCTATCCACTCTCTAGACCTTTGGGAAATCTGGGTCCCTCTCCTGATTTGATCCATTCGGCCCCAAC
TCCAGAGTCGGGAATGGGAGATGAAACTAGTTTTCCACCCACTTTTGGACAAGTCCCACCCCTAGATCTGAAGCAAGCTCTACCAGCAGC
GTGTCCTGGAAGCCTGCCTGCCTGCCTGCCCGTCTGCACAGGTGTCTTGATCCAGCCCTGCGTCTTCGAGCCCCTGTGCCACCGGTCCCC
ACGGCCCGCCAGGAGTCTCTTTGTACCCACTAGGCTTCCCTGATGACCATCTGTCTGTCCGTCCCTGTTTTTGCTGTACATAACTCCTGC
TGCACCCTCTCCCCGCACACCCGTCACCCATGAGAGAGAGAAACCTCTCTAGGGAAAGGCAGGGTGGCTGCACCCAGCAACTAATCCAAA
TGGCAAATATTTTGTAACAAAATAGCCCAGAGGTATTTTATCTGTTCAATTCATAGAGTTTTAGAGATTATATTGAAAGATGTCACTTGA

>99331_99331_18_WNK1-IQSEC3_WNK1_chr12_863490_ENST00000537687_IQSEC3_chr12_247432_ENST00000538872_length(amino acids)=1183AA_BP=300
MSVLSEASSGSARTRPAAVPCRPLRGRLGPSRPFRSRIRARSPLSSEPTMSGGAAEKQSSTPGSLFLSPPAPAPKNGSSSDSSVGEKLGA
AAADAVTGRTEEYRRRRHTMDKDSRGAAATTTTTEHRFFRRSVICDSNATALELPGLPLSLPQPSIPAAVPQSAPPEPHREETVTATATS
QVAQQPPAAAAPGEQAVAGPAPSTVPSSTSKDRPVSQPSLVGSKEEPPPARSGSGGGSAKEPQEERSQQQDDIEELETKAVGMSNDGRFL
KFDIEIGRGSFKTVYKGLDTETTVEVAWCELQIEMLEHKYGGHLVSRRAACTIQTAFRQYQLSKNFEKIRNSLLESRLPRRISLRKVRSP
TAESLAAEKALMEGYGLVGLPLVRSPSLPPTFAGTLTELEDSFTEQVQSLAKSIDDALSTWSLKTMCSLRESGAYQLHQALQAAAGPPGL
EAEGRAPESAGPGPGDDAAETPGLPPAHSGTLMMAFRDVTVQIANQNISVSSSTALSVANCLGAQTVQAPAEPAAGKAEQGETSGREAPE
APAVGREDASAEDSCAEAAASGAADGATAPKTEEEEEEEETAEVGRGAEAEAGDLEQLSSSSTSTKSAKSGSEASASASKDALQAMILSL
PRYHCENPASCKSPTLSTDTLRKRLYRIGLNLFNINPDKGIQFLISRGFIPDTPIGVAHFLLQRKGLSRQMIGEFLGNSKKQFNRDVLDC
VVDEMDFSSMELDEALRKFQAHIRVQGEAQKVERLIEAFSQRYCMCNPEVVQQFHNPDTIFILAFAIILLNTDMYSPNIKPDRKMMLEDF
IRNLRGVDDGADIPRELVVGIYERIQQKELKSNEDHVTYVTKVEKSIVGMKTVLSVPHRRLVCCSRLFEVTDVNKLQKQAAHQREVFLFN
DLLVILKLCPKKKSSSTYTFCKSVGLLGMQFQLFENEYYSHGITLVTPLSGSEKKQVLHFCALGSDEMQKFVEDLKESIAEVTELEQIRI
EWELEKQQGTKTLSFKPCGAQGDPQSKQGSPTAKREAALRERPAESTVEVSIHNRLQTSQHNSGLGAERGAPVPPPDLQPSPPRQQTPPL
PPPPPTPPGTLVQCQQIVKVIVLDKPCLARMEPLLSQALSCYTSSSSDSCGSTPLGGPGSPVKVTHQPPLPPPPPPYNHPHQFCPPGSLL

--------------------------------------------------------------
>99331_99331_19_WNK1-IQSEC3_WNK1_chr12_863490_ENST00000537687_IQSEC3_chr12_247433_ENST00000326261_length(transcript)=7362nt_BP=1402nt
CCGGCCCTTCGCCTCTGGGCGATGGGCGACCTGTGAGGCCGGTCCCCATCGCTGGGGGCGCGTGTGGGAGGAGGCGGCCGCCCGAGTGAC
CGGGAGCCGGGCCGCGGCCTTCCCTCGCCCGCCTCGGCCCCTCCCACTCCTCTGCCCCGGGGCCGCCACCGCCCGGGCGTCGGACCTGGT
CCCGTGCTCGCGGTGCCGCCGCCCTCTGGGCCTAGCCCGCCCAGCTCGGCGAGCGGCGGCAGTGGGAGCCGCGTCCGCCGCATCCGCCTC
GACTCGGTGCCGGCCCCTGGCCCTCCCCTCATGACTGCGGCGCCTCTGCTGCCACCGCCCGCCCGGCCGCCGCTCGCCGCAGGATGGATG
CGGACCGTGCGGCGCTAACCCCCGTGGCTCAGCTCCCGAATCGCCCGCCTTCGAGCCCTCCTCGTGAGCCGCAGCAGCCTCGGTGCCAGC
CCCCGCCGCAGCTGGGCCCAGCGGTCCGCCTGTCCCTCGTTGCGGCTTGTCGGTGCTGAGTGAGGCGTCGTCCGGGTCGGCGCGAACCCG
CCCGGCCGCGGTTCCCTGCAGACCTCTGCGCGGGCGGCTCGGCCCTTCACGCCCTTTTCGTTCACGAATCCGAGCCCGCTCGCCTCTCTC
CAGCGAACCGACCATGTCTGGCGGCGCCGCAGAGAAGCAGAGCAGCACTCCCGGTTCCCTGTTCCTCTCGCCGCCGGCTCCTGCCCCCAA
GAATGGCTCCAGCTCCGATTCCTCCGTGGGGGAGAAACTGGGAGCCGCGGCCGCCGACGCTGTGACCGGCAGGACCGAGGAGTACAGGCG
CCGCCGCCACACTATGGACAAGGACAGCCGTGGGGCGGCCGCGACCACTACCACCACTGAGCACCGCTTCTTCCGCCGGAGCGTCATCTG
TGACTCCAATGCCACTGCACTGGAGCTTCCCGGCCTTCCTCTTTCCCTGCCCCAGCCCAGCATCCCCGCGGCTGTCCCGCAGAGTGCTCC
ACCGGAGCCCCACCGGGAAGAGACCGTGACCGCCACCGCCACTTCCCAGGTAGCCCAGCAGCCTCCAGCCGCTGCCGCCCCTGGGGAACA
GGCCGTCGCGGGCCCTGCCCCCTCGACTGTCCCCAGCAGTACCAGCAAAGACCGCCCAGTGTCCCAGCCTAGCCTTGTGGGGAGCAAAGA
GGAGCCGCCGCCGGCGAGAAGTGGCAGCGGCGGCGGCAGCGCCAAGGAGCCACAGGAGGAACGGAGCCAGCAGCAGGATGATATCGAAGA
GCTGGAGACCAAGGCCGTGGGAATGTCTAACGATGGCCGCTTTCTCAAGTTTGACATCGAAATCGGCAGAGGCTCCTTTAAGACGGTCTA
CAAAGGTCTGGACACTGAAACCACCGTGGAAGTCGCCTGGTGTGAACTGCAGATTGAAATGCTAGAACATAAGTACGGCGGTCACCTGGT
GTCCCGGCGCGCCGCTTGCACCATCCAAACCGCCTTCCGCCAATACCAGCTCAGCAAGAACTTCGAGAAAATCCGCAACTCGCTTCTGGA
GAGCCGCCTGCCACGGCGGATCTCCCTGCGCAAGGTGCGGTCACCCACGGCCGAGAGCCTGGCGGCCGAGAAAGCGCTCATGGAGGGCTA
CGGCCTCGTGGGGCTGCCGCTGGTGCGCTCGCCCTCCCTGCCGCCCACCTTCGCAGGCACCCTCACCGAGCTGGAGGACTCCTTCACCGA
GCAGGTGCAATCCCTGGCCAAGTCCATCGACGACGCGCTCAGCACGTGGAGCCTCAAGACCATGTGCTCCCTGCGGGAGAGTGGCGCTTA
CCAGCTCCACCAGGCCCTGCAGGCGGCCGCGGGGCCCCCAGGCCTGGAGGCCGAGGGGCGGGCGCCGGAGAGCGCGGGCCCCGGGCCCGG
GGATGACGCCGCGGAGACCCCCGGCCTGCCCCCGGCCCACAGCGGGACCCTCATGATGGCTTTCCGGGACGTCACGGTGCAGATCGCCAA
CCAGAACATATCCGTCTCCTCCTCCACGGCTCTGTCGGTGGCCAACTGCCTGGGCGCTCAGACGGTCCAGGCCCCCGCAGAGCCCGCGGC
GGGCAAGGCCGAGCAGGGCGAGACCTCTGGGCGGGAGGCCCCGGAAGCCCCCGCCGTGGGCCGGGAGGACGCGTCAGCCGAGGACTCATG
CGCAGAGGCTGCGGCTAGTGGGGCGGCGGATGGGGCCACAGCCCCCAAAACAGAGGAGGAAGAGGAGGAGGAGGAGACGGCGGAGGTGGG
GAGAGGGGCCGAGGCCGAGGCAGGCGACTTGGAGCAGCTGAGCAGCAGCAGCACGTCCACCAAGTCCGCCAAGTCAGGCTCGGAGGCGTC
GGCCTCCGCCTCCAAGGACGCCCTGCAGGCCATGATCCTGAGCCTGCCGCGCTACCACTGCGAGAACCCAGCCAGCTGCAAGTCGCCCAC
GCTCTCCACCGACACCCTGCGCAAGCGGCTCTACCGCATCGGCCTCAACCTCTTCAACATAAACCCCGACAAGGGCATCCAGTTCCTGAT
CTCACGCGGCTTCATCCCGGACACCCCCATCGGTGTGGCCCATTTCCTCCTCCAGCGAAAGGGCCTCAGCCGCCAGATGATTGGAGAGTT
CCTGGGCAACAGCAAGAAGCAGTTCAACCGCGACGTGCTGGACTGCGTGGTGGACGAGATGGACTTCTCCAGCATGGAGCTGGACGAGGC
CCTGCGCAAGTTCCAGGCACACATCCGTGTGCAGGGGGAGGCTCAGAAGGTGGAGCGGCTCATTGAGGCCTTCAGCCAGCGCTACTGCAT
GTGCAACCCCGAAGTGGTTCAGCAGTTCCACAACCCCGACACCATCTTCATCCTCGCCTTCGCCATCATCCTCCTCAACACCGACATGTA
CAGCCCCAACATCAAGCCTGACCGGAAGATGATGCTGGAGGACTTCATCCGAAACCTTCGAGGTGTGGACGATGGCGCTGACATCCCCAG
GGAGCTGGTGGTAGGCATCTATGAGAGGATACAGCAGAAGGAGCTCAAGTCCAATGAGGACCACGTCACGTACGTCACCAAGGTGGAGAA
GTCCATTGTGGGCATGAAGACAGTGCTGTCCGTGCCCCACCGCCGCCTGGTGTGCTGCAGCCGGCTCTTCGAGGTGACGGATGTGAACAA
GCTGCAGAAGCAGGCAGCGCATCAGAGGGAGGTGTTCCTCTTCAATGACCTGCTGGTGATTCTCAAACTTTGCCCGAAGAAGAAGAGCTC
CTCCACGTACACCTTTTGCAAGTCAGTTGGCCTGCTGGGCATGCAGTTCCAGCTCTTTGAGAACGAGTATTACTCTCATGGCATCACACT
GGTGACCCCGCTCTCGGGCTCCGAGAAGAAGCAGGTGCTGCATTTCTGTGCCCTGGGCTCGGACGAGATGCAGAAGTTCGTGGAGGACCT
GAAGGAGTCCATTGCTGAGGTGACGGAGCTGGAGCAGATCCGAATAGAGTGGGAGCTGGAGAAGCAGCAGGGAACAAAGACACTCTCCTT
CAAGCCCTGCGGAGCCCAGGGGGACCCACAGTCAAAGCAAGGATCGCCGACAGCCAAAAGGGAAGCCGCGCTCAGGGAGAGGCCGGCGGA
GAGCACGGTGGAGGTGTCAATTCACAACAGGCTTCAAACGTCCCAGCACAACTCCGGGCTGGGGGCCGAGAGGGGAGCGCCGGTGCCGCC
GCCAGACCTGCAGCCTAGCCCCCCGAGACAGCAGACCCCACCACTGCCGCCGCCGCCACCCACGCCCCCGGGCACCCTGGTGCAGTGCCA
GCAAATTGTCAAGGTCATTGTCCTGGACAAGCCCTGCCTGGCCCGCATGGAGCCCCTGCTGAGCCAGGCTCTCTCCTGCTACACCTCGTC
GTCCTCTGACTCCTGCGGCTCCACACCCCTGGGCGGTCCCGGCTCTCCGGTCAAGGTCACCCACCAGCCTCCGCTGCCCCCGCCCCCACC
CCCCTACAACCACCCTCACCAGTTCTGTCCCCCAGGCTCCCTGCTGCACGGGCACCGCTACTCCAGTGGCTCAAGGAGCCTGGTGTAGAC
TCTGCCCCACCACCCTGCTGTCCTGGGAGGGCTGGCCACTGGGGGGCCTGGGCTGCCCCTCCACTGCTCCCCATACCCTGGCACGATGCG
TTCCTGGTCACTGATCACCATCATTTTGGGAAGAGAATCCCAATCCCTGGCACCTGGGTTTGCCTCATCCAACCATCCTTCCCTTTCTCA
GCTGCACCCCCTCTGCAGATCTGAAGACACACCTCACTCTCCCAGGGCCCTACACAGCCAGACCCGGCGAGGCCTCCTCTTCCCCTGGCC
ACCACTTTCCCCCATTGGACCATGGACTGAAGAAAACGAGCTGAGGGTCTAACGAGCTTGCAGGCTTTGAGTCTGTTAGTGCCCGGGGCC
TCGGGCCTTGGGCAGCAGCATGAGGCTGGGCCGGCCGGCAGTGGAGCACTAGACAGAGTGGCTGGCTCGCAGCCCAGAACTAGTGCCTCT
GTAGCTGCACTGAGGGGAGGAGGGTTGGTCCCACCCCTGGAGGGACAGGTGGGAGGAGTGAGGAGGGGGCTTTTTCTGCCACCCCCGCCC
CCAAGCCTGAAACTCTCAGGAGTCTACTTCTTGGTCCCCAGGGACATTGGCTGTCCTGACCATGTCCTTCCCCCTCCTCCCAGGGCCTCT
GCTTCCTCAGGAGCTGCCCAGACTCCAGAAAAGCCTGGAAAAAGGGAGGCGGGAAGGGGAGCACTTTCGGCTTTCTATAGGTCAGTCCAG
CAGGGCCACGGGATCGCGAGGTCATGTATCTGCAAAATGCACCTTTTTAAAGAGTGTCTTAGTTCCCCAGCCCCAGCTAATACCCGGCCA
ATGCCGTGTACGCACCGGCATGTGCACGCAAACACGCATGAGAACCAGGCCATTCCTTCCGCTGTGGAAGCAGAACTGGAGACGGGGCAG
GAATGTGCCCAGCAGAGATGGGGCTCAGCCCGAGGCAGGGCTCCCTCCTGCATGAGGCTCGGCCCGAGGCAGGGCTCCCTCCTGCATGAG
TCTGTGGCCTCCAGGAGGGACTTGGGTGCAGATGTAAGCAAGAAAAACCGGGGCTCCAGAGGCATGTGCATTTCCCCTGCGCCCCTCAGC
CTTTAAATATTCCCTCCTCCTAGAAGGTTCTAGACCCCCCCCTTCCAGCAGGGGTGCCCAAGAGTCCCTGGACCCTCAAAATTGCAAAGG
AGACCCAAGCGGGGCTCGCTGACCTCCCAGGGCCCAGCAAGATGGGATAGCCAGCCTTAGGTGGCCCCACGAGCCCAAGCCTGGGGAAGG
GCCCCTCCCCAGCCAGACGAGAGGCAGCCACCCCAGAGACCACAGGAGCCGTACCATGGCCTGCGCAGTCAGGCCCTATCAGGATGTGTC
TGTCCCAAGCCTGGCCAGGCTCCAGTCCTGTGCCAGTAGCTCACTGCTGTCCTATGTGCAGGTCCCCCAACACTTGGAGCCTGTGGTTAA
GGCCTCCTGGGAGAGGCAGTGAGCATGAGTCAAAGGTGACATGGACTTGAATCTCCCCACCCCGCCCCGCCTGCAGTAGCCGGGCCAGGT
AGGAGGCAAGGATCATTCCCTGCTCCCAGAGGTTCCAGATGACCTAGTTTCGTTTTGTGTGTGTGTGTGTGTGGTCACCCAGACGTCACT
GTGATATCACCTAGTGAATCTATTTCTGGCCCTGTCTTCGTCGGCCCAGTTTCTGTAACTTGCAGCCAATTTGCCCTCTCCCCTGTGGCT
GCCAGCCCATCTGCCCCTCTGTGTCCTTGCTGCCCTGGCCCTCCTCTGTTTTCTGTAACAGATGCTCCAGTCATTGCCTTTCAGAGTGGA
GCAGATGACAGATGGGGTGCACGCATTCAGACACCTCTGATGCCCTTAGCCAGGGCAGGGATCGTCCTTAAAGTGAAGGCCTGGACAGGA
GGAGTCAGGGACTTGGGAGGAGGTGGAGCTGTGGGGATGGGAGTGGAGGAATCAAAATGAGGGAAGCTGAAAATAGAATGAAAACGATGA
CTAAGAGGCAGGGAGTGCGAGGTATGGGGGAATAGGAACTATGAGCTAAATATACTTATGGGGTGGGGGCCGTGGGGGCCAGGGACACTC
TCCCAGACAGCCCTGACCCGCCAGGCAGGACCCCGTCCCCTGCTCACACAGCTCTTCAAACTTACCAAGGACAGGCAGGACCCCGTCCCC
TGCTCACACAGCTCTTCAAGCTTACCAAGTCCCCTGTTGAGGGCACAGCAACCCCAGGCCCTCCCTCCCACCTCAGCTGAAGCCCCAATC
TTCCAAATCGGAACCAGCAAGTCTTAGGGCTGGCACGCATCTGGGCCTCTAGCTGAGAACCCGGACTCTCAGGCACCTCAGTGCCCCTGC
CCCAGGGCAGAGGCCCACCCCGTGGGTTGGTGCAGTGGCTGCCCTGGGCTCCACGGGCAGCACAGGGAGTCTGTCCAGGAAGCAGCCCAG
CCGGGGTCAGTATTCCGTGGAGCCAGTCCTGAGCTGGGAGGGGCATTTAACACCCCTGAGGGCCTGGGGCAGGACACAGCTGGCCCTCCT
CATTGTCAGGGGAAGCAAGTGCCCAACATCTGTAACCTCCCTTCCCTGCTCAGTCCCCAGGCCAAGGTTGGGACCCCTCTCCATCCCTGT
CCCCAGAGCCTAGACCTCAGGGACCTAGGAAAAGCCTCCTGCTCCCTCCCCACGGCAGCAGACAGGGCAGGGCCTCCAGCCCCCAGAGGG
CCGGTGGGGGGTGCTCTCGGGCCTTCCTGCTCTCCTAAGGTTGCGGGGACAGTAGAGTGCTGAGCCCCAGACCCAGTCACCCCAAGATGG
CCCCACTCTATCCACTCTCTAGACCTTTGGGAAATCTGGGTCCCTCTCCTGATTTGATCCATTCGGCCCCAACTCCAGAGTCGGGAATGG
GAGATGAAACTAGTTTTCCACCCACTTTTGGACAAGTCCCACCCCTAGATCTGAAGCAAGCTCTACCAGCAGCGTGTCCTGGAAGCCTGC
CTGCCTGCCTGCCCGTCTGCACAGGTGTCTTGATCCAGCCCTGCGTCTTCGAGCCCCTGTGCCACCGGTCCCCACGGCCCGCCAGGAGTC
TCTTTGTACCCACTAGGCTTCCCTGATGACCATCTGTCTGTCCGTCCCTGTTTTTGCTGTACATAACTCCTGCTGCACCCTCTCCCCGCA
CACCCGTCACCCATGAGAGAGAGAAACCTCTCTAGGGAAAGGCAGGGTGGCTGCACCCAGCAACTAATCCAAATGGCAAATATTTTGTAA

>99331_99331_19_WNK1-IQSEC3_WNK1_chr12_863490_ENST00000537687_IQSEC3_chr12_247433_ENST00000326261_length(amino acids)=1183AA_BP=300
MSVLSEASSGSARTRPAAVPCRPLRGRLGPSRPFRSRIRARSPLSSEPTMSGGAAEKQSSTPGSLFLSPPAPAPKNGSSSDSSVGEKLGA
AAADAVTGRTEEYRRRRHTMDKDSRGAAATTTTTEHRFFRRSVICDSNATALELPGLPLSLPQPSIPAAVPQSAPPEPHREETVTATATS
QVAQQPPAAAAPGEQAVAGPAPSTVPSSTSKDRPVSQPSLVGSKEEPPPARSGSGGGSAKEPQEERSQQQDDIEELETKAVGMSNDGRFL
KFDIEIGRGSFKTVYKGLDTETTVEVAWCELQIEMLEHKYGGHLVSRRAACTIQTAFRQYQLSKNFEKIRNSLLESRLPRRISLRKVRSP
TAESLAAEKALMEGYGLVGLPLVRSPSLPPTFAGTLTELEDSFTEQVQSLAKSIDDALSTWSLKTMCSLRESGAYQLHQALQAAAGPPGL
EAEGRAPESAGPGPGDDAAETPGLPPAHSGTLMMAFRDVTVQIANQNISVSSSTALSVANCLGAQTVQAPAEPAAGKAEQGETSGREAPE
APAVGREDASAEDSCAEAAASGAADGATAPKTEEEEEEEETAEVGRGAEAEAGDLEQLSSSSTSTKSAKSGSEASASASKDALQAMILSL
PRYHCENPASCKSPTLSTDTLRKRLYRIGLNLFNINPDKGIQFLISRGFIPDTPIGVAHFLLQRKGLSRQMIGEFLGNSKKQFNRDVLDC
VVDEMDFSSMELDEALRKFQAHIRVQGEAQKVERLIEAFSQRYCMCNPEVVQQFHNPDTIFILAFAIILLNTDMYSPNIKPDRKMMLEDF
IRNLRGVDDGADIPRELVVGIYERIQQKELKSNEDHVTYVTKVEKSIVGMKTVLSVPHRRLVCCSRLFEVTDVNKLQKQAAHQREVFLFN
DLLVILKLCPKKKSSSTYTFCKSVGLLGMQFQLFENEYYSHGITLVTPLSGSEKKQVLHFCALGSDEMQKFVEDLKESIAEVTELEQIRI
EWELEKQQGTKTLSFKPCGAQGDPQSKQGSPTAKREAALRERPAESTVEVSIHNRLQTSQHNSGLGAERGAPVPPPDLQPSPPRQQTPPL
PPPPPTPPGTLVQCQQIVKVIVLDKPCLARMEPLLSQALSCYTSSSSDSCGSTPLGGPGSPVKVTHQPPLPPPPPPYNHPHQFCPPGSLL

--------------------------------------------------------------
>99331_99331_20_WNK1-IQSEC3_WNK1_chr12_863490_ENST00000537687_IQSEC3_chr12_247433_ENST00000538872_length(transcript)=7475nt_BP=1402nt
CCGGCCCTTCGCCTCTGGGCGATGGGCGACCTGTGAGGCCGGTCCCCATCGCTGGGGGCGCGTGTGGGAGGAGGCGGCCGCCCGAGTGAC
CGGGAGCCGGGCCGCGGCCTTCCCTCGCCCGCCTCGGCCCCTCCCACTCCTCTGCCCCGGGGCCGCCACCGCCCGGGCGTCGGACCTGGT
CCCGTGCTCGCGGTGCCGCCGCCCTCTGGGCCTAGCCCGCCCAGCTCGGCGAGCGGCGGCAGTGGGAGCCGCGTCCGCCGCATCCGCCTC
GACTCGGTGCCGGCCCCTGGCCCTCCCCTCATGACTGCGGCGCCTCTGCTGCCACCGCCCGCCCGGCCGCCGCTCGCCGCAGGATGGATG
CGGACCGTGCGGCGCTAACCCCCGTGGCTCAGCTCCCGAATCGCCCGCCTTCGAGCCCTCCTCGTGAGCCGCAGCAGCCTCGGTGCCAGC
CCCCGCCGCAGCTGGGCCCAGCGGTCCGCCTGTCCCTCGTTGCGGCTTGTCGGTGCTGAGTGAGGCGTCGTCCGGGTCGGCGCGAACCCG
CCCGGCCGCGGTTCCCTGCAGACCTCTGCGCGGGCGGCTCGGCCCTTCACGCCCTTTTCGTTCACGAATCCGAGCCCGCTCGCCTCTCTC
CAGCGAACCGACCATGTCTGGCGGCGCCGCAGAGAAGCAGAGCAGCACTCCCGGTTCCCTGTTCCTCTCGCCGCCGGCTCCTGCCCCCAA
GAATGGCTCCAGCTCCGATTCCTCCGTGGGGGAGAAACTGGGAGCCGCGGCCGCCGACGCTGTGACCGGCAGGACCGAGGAGTACAGGCG
CCGCCGCCACACTATGGACAAGGACAGCCGTGGGGCGGCCGCGACCACTACCACCACTGAGCACCGCTTCTTCCGCCGGAGCGTCATCTG
TGACTCCAATGCCACTGCACTGGAGCTTCCCGGCCTTCCTCTTTCCCTGCCCCAGCCCAGCATCCCCGCGGCTGTCCCGCAGAGTGCTCC
ACCGGAGCCCCACCGGGAAGAGACCGTGACCGCCACCGCCACTTCCCAGGTAGCCCAGCAGCCTCCAGCCGCTGCCGCCCCTGGGGAACA
GGCCGTCGCGGGCCCTGCCCCCTCGACTGTCCCCAGCAGTACCAGCAAAGACCGCCCAGTGTCCCAGCCTAGCCTTGTGGGGAGCAAAGA
GGAGCCGCCGCCGGCGAGAAGTGGCAGCGGCGGCGGCAGCGCCAAGGAGCCACAGGAGGAACGGAGCCAGCAGCAGGATGATATCGAAGA
GCTGGAGACCAAGGCCGTGGGAATGTCTAACGATGGCCGCTTTCTCAAGTTTGACATCGAAATCGGCAGAGGCTCCTTTAAGACGGTCTA
CAAAGGTCTGGACACTGAAACCACCGTGGAAGTCGCCTGGTGTGAACTGCAGATTGAAATGCTAGAACATAAGTACGGCGGTCACCTGGT
GTCCCGGCGCGCCGCTTGCACCATCCAAACCGCCTTCCGCCAATACCAGCTCAGCAAGAACTTCGAGAAAATCCGCAACTCGCTTCTGGA
GAGCCGCCTGCCACGGCGGATCTCCCTGCGCAAGGTGCGGTCACCCACGGCCGAGAGCCTGGCGGCCGAGAAAGCGCTCATGGAGGGCTA
CGGCCTCGTGGGGCTGCCGCTGGTGCGCTCGCCCTCCCTGCCGCCCACCTTCGCAGGCACCCTCACCGAGCTGGAGGACTCCTTCACCGA
GCAGGTGCAATCCCTGGCCAAGTCCATCGACGACGCGCTCAGCACGTGGAGCCTCAAGACCATGTGCTCCCTGCGGGAGAGTGGCGCTTA
CCAGCTCCACCAGGCCCTGCAGGCGGCCGCGGGGCCCCCAGGCCTGGAGGCCGAGGGGCGGGCGCCGGAGAGCGCGGGCCCCGGGCCCGG
GGATGACGCCGCGGAGACCCCCGGCCTGCCCCCGGCCCACAGCGGGACCCTCATGATGGCTTTCCGGGACGTCACGGTGCAGATCGCCAA
CCAGAACATATCCGTCTCCTCCTCCACGGCTCTGTCGGTGGCCAACTGCCTGGGCGCTCAGACGGTCCAGGCCCCCGCAGAGCCCGCGGC
GGGCAAGGCCGAGCAGGGCGAGACCTCTGGGCGGGAGGCCCCGGAAGCCCCCGCCGTGGGCCGGGAGGACGCGTCAGCCGAGGACTCATG
CGCAGAGGCTGCGGCTAGTGGGGCGGCGGATGGGGCCACAGCCCCCAAAACAGAGGAGGAAGAGGAGGAGGAGGAGACGGCGGAGGTGGG
GAGAGGGGCCGAGGCCGAGGCAGGCGACTTGGAGCAGCTGAGCAGCAGCAGCACGTCCACCAAGTCCGCCAAGTCAGGCTCGGAGGCGTC
GGCCTCCGCCTCCAAGGACGCCCTGCAGGCCATGATCCTGAGCCTGCCGCGCTACCACTGCGAGAACCCAGCCAGCTGCAAGTCGCCCAC
GCTCTCCACCGACACCCTGCGCAAGCGGCTCTACCGCATCGGCCTCAACCTCTTCAACATAAACCCCGACAAGGGCATCCAGTTCCTGAT
CTCACGCGGCTTCATCCCGGACACCCCCATCGGTGTGGCCCATTTCCTCCTCCAGCGAAAGGGCCTCAGCCGCCAGATGATTGGAGAGTT
CCTGGGCAACAGCAAGAAGCAGTTCAACCGCGACGTGCTGGACTGCGTGGTGGACGAGATGGACTTCTCCAGCATGGAGCTGGACGAGGC
CCTGCGCAAGTTCCAGGCACACATCCGTGTGCAGGGGGAGGCTCAGAAGGTGGAGCGGCTCATTGAGGCCTTCAGCCAGCGCTACTGCAT
GTGCAACCCCGAAGTGGTTCAGCAGTTCCACAACCCCGACACCATCTTCATCCTCGCCTTCGCCATCATCCTCCTCAACACCGACATGTA
CAGCCCCAACATCAAGCCTGACCGGAAGATGATGCTGGAGGACTTCATCCGAAACCTTCGAGGTGTGGACGATGGCGCTGACATCCCCAG
GGAGCTGGTGGTAGGCATCTATGAGAGGATACAGCAGAAGGAGCTCAAGTCCAATGAGGACCACGTCACGTACGTCACCAAGGTGGAGAA
GTCCATTGTGGGCATGAAGACAGTGCTGTCCGTGCCCCACCGCCGCCTGGTGTGCTGCAGCCGGCTCTTCGAGGTGACGGATGTGAACAA
GCTGCAGAAGCAGGCAGCGCATCAGAGGGAGGTGTTCCTCTTCAATGACCTGCTGGTGATTCTCAAACTTTGCCCGAAGAAGAAGAGCTC
CTCCACGTACACCTTTTGCAAGTCAGTTGGCCTGCTGGGCATGCAGTTCCAGCTCTTTGAGAACGAGTATTACTCTCATGGCATCACACT
GGTGACCCCGCTCTCGGGCTCCGAGAAGAAGCAGGTGCTGCATTTCTGTGCCCTGGGCTCGGACGAGATGCAGAAGTTCGTGGAGGACCT
GAAGGAGTCCATTGCTGAGGTGACGGAGCTGGAGCAGATCCGAATAGAGTGGGAGCTGGAGAAGCAGCAGGGAACAAAGACACTCTCCTT
CAAGCCCTGCGGAGCCCAGGGGGACCCACAGTCAAAGCAAGGATCGCCGACAGCCAAAAGGGAAGCCGCGCTCAGGGAGAGGCCGGCGGA
GAGCACGGTGGAGGTGTCAATTCACAACAGGCTTCAAACGTCCCAGCACAACTCCGGGCTGGGGGCCGAGAGGGGAGCGCCGGTGCCGCC
GCCAGACCTGCAGCCTAGCCCCCCGAGACAGCAGACCCCACCACTGCCGCCGCCGCCACCCACGCCCCCGGGCACCCTGGTGCAGTGCCA
GCAAATTGTCAAGGTCATTGTCCTGGACAAGCCCTGCCTGGCCCGCATGGAGCCCCTGCTGAGCCAGGCTCTCTCCTGCTACACCTCGTC
GTCCTCTGACTCCTGCGGCTCCACACCCCTGGGCGGTCCCGGCTCTCCGGTCAAGGTCACCCACCAGCCTCCGCTGCCCCCGCCCCCACC
CCCCTACAACCACCCTCACCAGTTCTGTCCCCCAGGCTCCCTGCTGCACGGGCACCGCTACTCCAGTGGCTCAAGGAGCCTGGTGTAGAC
TCTGCCCCACCACCCTGCTGTCCTGGGAGGGCTGGCCACTGGGGGGCCTGGGCTGCCCCTCCACTGCTCCCCATACCCTGGCACGATGCG
TTCCTGGTCACTGATCACCATCATTTTGGGAAGAGAATCCCAATCCCTGGCACCTGGGTTTGCCTCATCCAACCATCCTTCCCTTTCTCA
GCTGCACCCCCTCTGCAGATCTGAAGACACACCTCACTCTCCCAGGGCCCTACACAGCCAGACCCGGCGAGGCCTCCTCTTCCCCTGGCC
ACCACTTTCCCCCATTGGACCATGGACTGAAGAAAACGAGCTGAGGGTCTAACGAGCTTGCAGGCTTTGAGTCTGTTAGTGCCCGGGGCC
TCGGGCCTTGGGCAGCAGCATGAGGCTGGGCCGGCCGGCAGTGGAGCACTAGACAGAGTGGCTGGCTCGCAGCCCAGAACTAGTGCCTCT
GTAGCTGCACTGAGGGGAGGAGGGTTGGTCCCACCCCTGGAGGGACAGGTGGGAGGAGTGAGGAGGGGGCTTTTTCTGCCACCCCCGCCC
CCAAGCCTGAAACTCTCAGGAGTCTACTTCTTGGTCCCCAGGGACATTGGCTGTCCTGACCATGTCCTTCCCCCTCCTCCCAGGGCCTCT
GCTTCCTCAGGAGCTGCCCAGACTCCAGAAAAGCCTGGAAAAAGGGAGGCGGGAAGGGGAGCACTTTCGGCTTTCTATAGGTCAGTCCAG
CAGGGCCACGGGATCGCGAGGTCATGTATCTGCAAAATGCACCTTTTTAAAGAGTGTCTTAGTTCCCCAGCCCCAGCTAATACCCGGCCA
ATGCCGTGTACGCACCGGCATGTGCACGCAAACACGCATGAGAACCAGGCCATTCCTTCCGCTGTGGAAGCAGAACTGGAGACGGGGCAG
GAATGTGCCCAGCAGAGATGGGGCTCAGCCCGAGGCAGGGCTCCCTCCTGCATGAGGCTCGGCCCGAGGCAGGGCTCCCTCCTGCATGAG
TCTGTGGCCTCCAGGAGGGACTTGGGTGCAGATGTAAGCAAGAAAAACCGGGGCTCCAGAGGCATGTGCATTTCCCCTGCGCCCCTCAGC
CTTTAAATATTCCCTCCTCCTAGAAGGTTCTAGACCCCCCCCTTCCAGCAGGGGTGCCCAAGAGTCCCTGGACCCTCAAAATTGCAAAGG
AGACCCAAGCGGGGCTCGCTGACCTCCCAGGGCCCAGCAAGATGGGATAGCCAGCCTTAGGTGGCCCCACGAGCCCAAGCCTGGGGAAGG
GCCCCTCCCCAGCCAGACGAGAGGCAGCCACCCCAGAGACCACAGGAGCCGTACCATGGCCTGCGCAGTCAGGCCCTATCAGGATGTGTC
TGTCCCAAGCCTGGCCAGGCTCCAGTCCTGTGCCAGTAGCTCACTGCTGTCCTATGTGCAGGTCCCCCAACACTTGGAGCCTGTGGTTAA
GGCCTCCTGGGAGAGGCAGTGAGCATGAGTCAAAGGTGACATGGACTTGAATCTCCCCACCCCGCCCCGCCTGCAGTAGCCGGGCCAGGT
AGGAGGCAAGGATCATTCCCTGCTCCCAGAGGTTCCAGATGACCTAGTTTCGTTTTGTGTGTGTGTGTGTGTGGTCACCCAGACGTCACT
GTGATATCACCTAGTGAATCTATTTCTGGCCCTGTCTTCGTCGGCCCAGTTTCTGTAACTTGCAGCCAATTTGCCCTCTCCCCTGTGGCT
GCCAGCCCATCTGCCCCTCTGTGTCCTTGCTGCCCTGGCCCTCCTCTGTTTTCTGTAACAGATGCTCCAGTCATTGCCTTTCAGAGTGGA
GCAGATGACAGATGGGGTGCACGCATTCAGACACCTCTGATGCCCTTAGCCAGGGCAGGGATCGTCCTTAAAGTGAAGGCCTGGACAGGA
GGAGTCAGGGACTTGGGAGGAGGTGGAGCTGTGGGGATGGGAGTGGAGGAATCAAAATGAGGGAAGCTGAAAATAGAATGAAAACGATGA
CTAAGAGGCAGGGAGTGCGAGGTATGGGGGAATAGGAACTATGAGCTAAATATACTTATGGGGTGGGGGCCGTGGGGGCCAGGGACACTC
TCCCAGACAGCCCTGACCCGCCAGGCAGGACCCCGTCCCCTGCTCACACAGCTCTTCAAACTTACCAAGGACAGGCAGGACCCCGTCCCC
TGCTCACACAGCTCTTCAAGCTTACCAAGGACAGGCAGAACCCCGTCCCCTGCTCACACAGCTCTTCAAGCTTACCAAGGACAGGCAGGA
CCCCGTCCCCTGCTCACACAGCTCTTCAAACTTACCAAGTGCCCTCTCCCCTGTTGAGGGCACAGCAACCCCAGGCCCTCCCTCCCACCT
CAGCTGAAGCCCCAATCTTCCAAATCGGAACCAGCAAGTCTTAGGGCTGGCACGCATCTGGGCCTCTAGCTGAGAACCCGGACTCTCAGG
CACCTCAGTGCCCCTGCCCCAGGGCAGAGGCCCACCCCGTGGGTTGGTGCAGTGGCTGCCCTGGGCTCCACGGGCAGCACAGGGAGTCTG
TCCAGGAAGCAGCCCAGCCGGGGTCAGTATTCCGTGGAGCCAGTCCTGAGCTGGGAGGGGCATTTAACACCCCTGAGGGCCTGGGGCAGG
ACACAGCTGGCCCTCCTCATTGTCAGGGGAAGCAAGTGCCCAACATCTGTAACCTCCCTTCCCTGCTCAGTCCCCAGGCCAAGGTTGGGA
CCCCTCTCCATCCCTGTCCCCAGAGCCTAGACCTCAGGGACCTAGGAAAAGCCTCCTGCTCCCTCCCCACGGCAGCAGACAGGGCAGGGC
CTCCAGCCCCCAGAGGGCCGGTGGGGGGTGCTCTCGGGCCTTCCTGCTCTCCTAAGGTTGCGGGGACAGTAGAGTGCTGAGCCCCAGACC
CAGTCACCCCAAGATGGCCCCACTCTATCCACTCTCTAGACCTTTGGGAAATCTGGGTCCCTCTCCTGATTTGATCCATTCGGCCCCAAC
TCCAGAGTCGGGAATGGGAGATGAAACTAGTTTTCCACCCACTTTTGGACAAGTCCCACCCCTAGATCTGAAGCAAGCTCTACCAGCAGC
GTGTCCTGGAAGCCTGCCTGCCTGCCTGCCCGTCTGCACAGGTGTCTTGATCCAGCCCTGCGTCTTCGAGCCCCTGTGCCACCGGTCCCC
ACGGCCCGCCAGGAGTCTCTTTGTACCCACTAGGCTTCCCTGATGACCATCTGTCTGTCCGTCCCTGTTTTTGCTGTACATAACTCCTGC
TGCACCCTCTCCCCGCACACCCGTCACCCATGAGAGAGAGAAACCTCTCTAGGGAAAGGCAGGGTGGCTGCACCCAGCAACTAATCCAAA
TGGCAAATATTTTGTAACAAAATAGCCCAGAGGTATTTTATCTGTTCAATTCATAGAGTTTTAGAGATTATATTGAAAGATGTCACTTGA

>99331_99331_20_WNK1-IQSEC3_WNK1_chr12_863490_ENST00000537687_IQSEC3_chr12_247433_ENST00000538872_length(amino acids)=1183AA_BP=300
MSVLSEASSGSARTRPAAVPCRPLRGRLGPSRPFRSRIRARSPLSSEPTMSGGAAEKQSSTPGSLFLSPPAPAPKNGSSSDSSVGEKLGA
AAADAVTGRTEEYRRRRHTMDKDSRGAAATTTTTEHRFFRRSVICDSNATALELPGLPLSLPQPSIPAAVPQSAPPEPHREETVTATATS
QVAQQPPAAAAPGEQAVAGPAPSTVPSSTSKDRPVSQPSLVGSKEEPPPARSGSGGGSAKEPQEERSQQQDDIEELETKAVGMSNDGRFL
KFDIEIGRGSFKTVYKGLDTETTVEVAWCELQIEMLEHKYGGHLVSRRAACTIQTAFRQYQLSKNFEKIRNSLLESRLPRRISLRKVRSP
TAESLAAEKALMEGYGLVGLPLVRSPSLPPTFAGTLTELEDSFTEQVQSLAKSIDDALSTWSLKTMCSLRESGAYQLHQALQAAAGPPGL
EAEGRAPESAGPGPGDDAAETPGLPPAHSGTLMMAFRDVTVQIANQNISVSSSTALSVANCLGAQTVQAPAEPAAGKAEQGETSGREAPE
APAVGREDASAEDSCAEAAASGAADGATAPKTEEEEEEEETAEVGRGAEAEAGDLEQLSSSSTSTKSAKSGSEASASASKDALQAMILSL
PRYHCENPASCKSPTLSTDTLRKRLYRIGLNLFNINPDKGIQFLISRGFIPDTPIGVAHFLLQRKGLSRQMIGEFLGNSKKQFNRDVLDC
VVDEMDFSSMELDEALRKFQAHIRVQGEAQKVERLIEAFSQRYCMCNPEVVQQFHNPDTIFILAFAIILLNTDMYSPNIKPDRKMMLEDF
IRNLRGVDDGADIPRELVVGIYERIQQKELKSNEDHVTYVTKVEKSIVGMKTVLSVPHRRLVCCSRLFEVTDVNKLQKQAAHQREVFLFN
DLLVILKLCPKKKSSSTYTFCKSVGLLGMQFQLFENEYYSHGITLVTPLSGSEKKQVLHFCALGSDEMQKFVEDLKESIAEVTELEQIRI
EWELEKQQGTKTLSFKPCGAQGDPQSKQGSPTAKREAALRERPAESTVEVSIHNRLQTSQHNSGLGAERGAPVPPPDLQPSPPRQQTPPL
PPPPPTPPGTLVQCQQIVKVIVLDKPCLARMEPLLSQALSCYTSSSSDSCGSTPLGGPGSPVKVTHQPPLPPPPPPYNHPHQFCPPGSLL

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Top

Fusion Gene PPI Analysis for WNK1-IQSEC3

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for WNK1-IQSEC3

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for WNK1-IQSEC3

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source