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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:WRNIP1-C6orf62 (FusionGDB2 ID:99401)

Fusion Gene Summary for WRNIP1-C6orf62

check button Fusion gene summary
Fusion gene informationFusion gene name: WRNIP1-C6orf62
Fusion gene ID: 99401
HgeneTgene
Gene symbol

WRNIP1

C6orf62

Gene ID

56897

81688

Gene nameWRN helicase interacting protein 1chromosome 6 open reading frame 62
SynonymsCFAP93|FAP93|WHIP|bA420G6.2Nbla00237|XTP12|dJ30M3.2
Cytomap

6p25.2

6p22.3

Type of geneprotein-codingprotein-coding
DescriptionATPase WRNIP1Werner helicase interacting protein 1putative helicase RUVBLuncharacterized protein C6orf62HBV X-transactivated gene 12 proteinHBV X-transactivated protein 12HBV XAg-transactivated protein 12
Modification date2020031320200313
UniProtAcc.

Q9GZU0

Ensembl transtripts involved in fusion geneENST00000380769, ENST00000380771, 
ENST00000380773, ENST00000380764, 
ENST00000378102, ENST00000378119, 
ENST00000540769, 
Fusion gene scores* DoF score3 X 3 X 3=2715 X 11 X 6=990
# samples 315
** MAII scorelog2(3/27*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(15/990*10)=-2.72246602447109
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: WRNIP1 [Title/Abstract] AND C6orf62 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointWRNIP1(2766678)-C6orf62(24709139), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneWRNIP1

GO:0000731

DNA synthesis involved in DNA repair

15670210

HgeneWRNIP1

GO:0030174

regulation of DNA-dependent DNA replication initiation

15670210


check buttonFusion gene breakpoints across WRNIP1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across C6orf62 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4Non-CancerTCGA-BH-A1F0-11BWRNIP1chr6

2766678

+C6orf62chr6

24709139

-


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Fusion Gene ORF analysis for WRNIP1-C6orf62

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000380769ENST00000378102WRNIP1chr6

2766678

+C6orf62chr6

24709139

-
In-frameENST00000380769ENST00000378119WRNIP1chr6

2766678

+C6orf62chr6

24709139

-
In-frameENST00000380769ENST00000540769WRNIP1chr6

2766678

+C6orf62chr6

24709139

-
In-frameENST00000380771ENST00000378102WRNIP1chr6

2766678

+C6orf62chr6

24709139

-
In-frameENST00000380771ENST00000378119WRNIP1chr6

2766678

+C6orf62chr6

24709139

-
In-frameENST00000380771ENST00000540769WRNIP1chr6

2766678

+C6orf62chr6

24709139

-
In-frameENST00000380773ENST00000378102WRNIP1chr6

2766678

+C6orf62chr6

24709139

-
In-frameENST00000380773ENST00000378119WRNIP1chr6

2766678

+C6orf62chr6

24709139

-
In-frameENST00000380773ENST00000540769WRNIP1chr6

2766678

+C6orf62chr6

24709139

-
intron-3CDSENST00000380764ENST00000378102WRNIP1chr6

2766678

+C6orf62chr6

24709139

-
intron-3CDSENST00000380764ENST00000378119WRNIP1chr6

2766678

+C6orf62chr6

24709139

-
intron-3CDSENST00000380764ENST00000540769WRNIP1chr6

2766678

+C6orf62chr6

24709139

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000380773WRNIP1chr62766678+ENST00000378119C6orf62chr624709139-256810311671291374
ENST00000380773WRNIP1chr62766678+ENST00000540769C6orf62chr624709139-150510311671291374
ENST00000380773WRNIP1chr62766678+ENST00000378102C6orf62chr624709139-133310311671291374
ENST00000380771WRNIP1chr62766678+ENST00000378119C6orf62chr624709139-256810311671291374
ENST00000380771WRNIP1chr62766678+ENST00000540769C6orf62chr624709139-150510311671291374
ENST00000380771WRNIP1chr62766678+ENST00000378102C6orf62chr624709139-133310311671291374
ENST00000380769WRNIP1chr62766678+ENST00000378119C6orf62chr624709139-1930393207653148
ENST00000380769WRNIP1chr62766678+ENST00000540769C6orf62chr624709139-867393207653148
ENST00000380769WRNIP1chr62766678+ENST00000378102C6orf62chr624709139-695393207653148

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000380773ENST00000378119WRNIP1chr62766678+C6orf62chr624709139-0.0015296070.99847037
ENST00000380773ENST00000540769WRNIP1chr62766678+C6orf62chr624709139-0.0101260620.989874
ENST00000380773ENST00000378102WRNIP1chr62766678+C6orf62chr624709139-0.012118240.9878818
ENST00000380771ENST00000378119WRNIP1chr62766678+C6orf62chr624709139-0.0015296070.99847037
ENST00000380771ENST00000540769WRNIP1chr62766678+C6orf62chr624709139-0.0101260620.989874
ENST00000380771ENST00000378102WRNIP1chr62766678+C6orf62chr624709139-0.012118240.9878818
ENST00000380769ENST00000378119WRNIP1chr62766678+C6orf62chr624709139-0.0088317840.99116814
ENST00000380769ENST00000540769WRNIP1chr62766678+C6orf62chr624709139-0.0100806750.9899193
ENST00000380769ENST00000378102WRNIP1chr62766678+C6orf62chr624709139-0.0085841140.9914159

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Fusion Genomic Features for WRNIP1-C6orf62


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for WRNIP1-C6orf62


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr6:2766678/chr6:24709139)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.C6orf62

Q9GZU0

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneWRNIP1chr6:2766678chr6:24709139ENST00000380771+17144_215274641.0Compositional biasAla-rich
HgeneWRNIP1chr6:2766678chr6:24709139ENST00000380773+17144_215274666.0Compositional biasAla-rich
HgeneWRNIP1chr6:2766678chr6:24709139ENST00000380771+17270_276274641.0Nucleotide bindingATP
HgeneWRNIP1chr6:2766678chr6:24709139ENST00000380773+17270_276274666.0Nucleotide bindingATP
HgeneWRNIP1chr6:2766678chr6:24709139ENST00000380769+1717_4454446.0Zinc fingerUBZ4-type
HgeneWRNIP1chr6:2766678chr6:24709139ENST00000380771+1717_44274641.0Zinc fingerUBZ4-type
HgeneWRNIP1chr6:2766678chr6:24709139ENST00000380773+1717_44274666.0Zinc fingerUBZ4-type

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneWRNIP1chr6:2766678chr6:24709139ENST00000380764+16144_2150282.0Compositional biasAla-rich
HgeneWRNIP1chr6:2766678chr6:24709139ENST00000380769+17144_21554446.0Compositional biasAla-rich
HgeneWRNIP1chr6:2766678chr6:24709139ENST00000380764+16270_2760282.0Nucleotide bindingATP
HgeneWRNIP1chr6:2766678chr6:24709139ENST00000380769+17270_27654446.0Nucleotide bindingATP
HgeneWRNIP1chr6:2766678chr6:24709139ENST00000380764+1617_440282.0Zinc fingerUBZ4-type


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Fusion Gene Sequence for WRNIP1-C6orf62


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>99401_99401_1_WRNIP1-C6orf62_WRNIP1_chr6_2766678_ENST00000380769_C6orf62_chr6_24709139_ENST00000378102_length(transcript)=695nt_BP=393nt
GCGGCCGCCGCCGCGGCGGGGAGCGCGTCTCCGCGCAGCTGGGACGAGGCGGAGGCGCAGGAGGAGGAGGAGGCCGTGGGCGACGGCGAT
GGCGACGGGGACGCGGACGCGGACGGCGAGGACGACCCGGGGCACTGGGACGCGGACGCTGCCGAAGCCGCCACCGCCTTCGGGGCCAGT
GGCGGGGGCCGCCCGCACCCCCGGGCGCTGGCTGCCGAGGAGATCCGACAGATGCTACAGGGCAAGCCGCTGGCCGACACGATGCGTCCT
GACACGCTGCAGGATTACTTCGGGCAGAGCAAGGCCGTGGGCCAGGATACCCTGCTGCGCTCGCTCCTGGAGACCAACGAAATCCCCTCG
CTTATCCTGTGGGGGCCGCCGGGCTGCGGCAAGGCCAAATTTGAGTTTCATCATGGTGACTATGAAAAACAGTTTCTGCATGTACTGAGC
CGCAAGGACAAGACTGGAATCGTTGTCAACAATCCTAACCAGTCAGTGTTTCTCTTCATTGACAGACAGCACTTGCAGACTCCAAAAAAC
AAAGCTACAATCTTCAAGTTATGCAGCATCTGCCTCTACCTGCCACAGGAACAGCTCACCCACTGGGCAGTTGGCACCATAGAGGATCAC

>99401_99401_1_WRNIP1-C6orf62_WRNIP1_chr6_2766678_ENST00000380769_C6orf62_chr6_24709139_ENST00000378102_length(amino acids)=148AA_BP=62
MAAEEIRQMLQGKPLADTMRPDTLQDYFGQSKAVGQDTLLRSLLETNEIPSLILWGPPGCGKAKFEFHHGDYEKQFLHVLSRKDKTGIVV

--------------------------------------------------------------
>99401_99401_2_WRNIP1-C6orf62_WRNIP1_chr6_2766678_ENST00000380769_C6orf62_chr6_24709139_ENST00000378119_length(transcript)=1930nt_BP=393nt
GCGGCCGCCGCCGCGGCGGGGAGCGCGTCTCCGCGCAGCTGGGACGAGGCGGAGGCGCAGGAGGAGGAGGAGGCCGTGGGCGACGGCGAT
GGCGACGGGGACGCGGACGCGGACGGCGAGGACGACCCGGGGCACTGGGACGCGGACGCTGCCGAAGCCGCCACCGCCTTCGGGGCCAGT
GGCGGGGGCCGCCCGCACCCCCGGGCGCTGGCTGCCGAGGAGATCCGACAGATGCTACAGGGCAAGCCGCTGGCCGACACGATGCGTCCT
GACACGCTGCAGGATTACTTCGGGCAGAGCAAGGCCGTGGGCCAGGATACCCTGCTGCGCTCGCTCCTGGAGACCAACGAAATCCCCTCG
CTTATCCTGTGGGGGCCGCCGGGCTGCGGCAAGGCCAAATTTGAGTTTCATCATGGTGACTATGAAAAACAGTTTCTGCATGTACTGAGC
CGCAAGGACAAGACTGGAATCGTTGTCAACAATCCTAACCAGTCAGTGTTTCTCTTCATTGACAGACAGCACTTGCAGACTCCAAAAAAC
AAAGCTACAATCTTCAAGTTATGCAGCATCTGCCTCTACCTGCCACAGGAACAGCTCACCCACTGGGCAGTTGGCACCATAGAGGATCAC
CTCCGTCCTTATATGCCAGAGTAGAGTACTGACCAGCAAAATGGAGAAGATCAGAGAATGCAGCAGCAGTTTTTTTTCTTGTTTTCTTAC
CACTTTATTCTTTCAGAGTTTAAAGAAAATGGACTCATGCACAGAACACTATGCATTTTGAAACTTGTTCATCCTGGATTTTTTTAAATC
ATTTTTATCTCAGAACTTAAACAAAAATTAGATGTCGTGCACGGACTGTGTGAAAGAAGATGCTTTGCATATTTGCTGCACTGCATCAGT
ATCTTACTAAAAATGTGAAATGAAAGGACTATTGTACACTGAAATGCTTAAATGTATCTGAAAGCACAAGGTGATACTCATTTTTATGGT
CTTCCCATTTGTGCTGGTTTTTGCCTCTTTGACATCTGTCATCAGTATTTAGAGGGTGAGAAGTGAATGTAACAGGTATAAATAACATTT
TTAAAAACAATAACTTTGCTATAATCACAGTTGTTCCAGAGCACTGTCAGATACATTCTAATGACCAGAACTGGTTTAAAAAAAGAAAAT
ACAACCATGGGAAAGAAATCTTAAATGAAAAACGCATCTCATTGTAGGCATTTTTGCCTCATATTTTACTGGGCCATGTTTGTTTCCTGG
TACTCATGTATTTTTTTTTTCCAGATCTCTTTCCCCAAGTTGCTATTGTAAGAGTATTCTGCTGCGTGTGGATGCAGTTATACACATTAA
AGCAGATCTGGAGTCTGAAGTAGCTATAAAGCAGCTATAAAACAGAAATACATGCATAGCTGCAGAAACCATGATAGGTAGAGGACTTTT
CTTTTGGTTTTGTTTTGTTTTGTTTTGTTTTGTTTTTGGTTTTACAGAGAAGAGATTTTTATTACAAAGAAAAAAATTCCAGTGAATTGT
GCAGAAATGCTGGTTTTTACACCATCCTAAAGAAAAACTTTACAAGGGTGTTTTGGAGTAGAAAAAAGGTTATAAAGTTGGAATCTTAAA
TTGTAAAATTAACCATTGAGTGTCAAAGTTCTAAAAGCAGAACTCATTTTGTGCAATGAACATAAGGAAAGACTACTGTATAGGTTTTTT
TTTTTTTCTCCTTTTAAATGAAGAAAAGCTTTGCTTAAGGGTTGCATACTTTTATTGGAGTAAATCTGAATGATCCTACTCCTTTGGAGT
AAAACTAGTGCTTACCAGTTTCCAATTGTATTTAGCTTCTGGTTGGAATTTGAAAAAAAAAGAAAAAAAGAAAAAGAAAACCTAAATAAA

>99401_99401_2_WRNIP1-C6orf62_WRNIP1_chr6_2766678_ENST00000380769_C6orf62_chr6_24709139_ENST00000378119_length(amino acids)=148AA_BP=62
MAAEEIRQMLQGKPLADTMRPDTLQDYFGQSKAVGQDTLLRSLLETNEIPSLILWGPPGCGKAKFEFHHGDYEKQFLHVLSRKDKTGIVV

--------------------------------------------------------------
>99401_99401_3_WRNIP1-C6orf62_WRNIP1_chr6_2766678_ENST00000380769_C6orf62_chr6_24709139_ENST00000540769_length(transcript)=867nt_BP=393nt
GCGGCCGCCGCCGCGGCGGGGAGCGCGTCTCCGCGCAGCTGGGACGAGGCGGAGGCGCAGGAGGAGGAGGAGGCCGTGGGCGACGGCGAT
GGCGACGGGGACGCGGACGCGGACGGCGAGGACGACCCGGGGCACTGGGACGCGGACGCTGCCGAAGCCGCCACCGCCTTCGGGGCCAGT
GGCGGGGGCCGCCCGCACCCCCGGGCGCTGGCTGCCGAGGAGATCCGACAGATGCTACAGGGCAAGCCGCTGGCCGACACGATGCGTCCT
GACACGCTGCAGGATTACTTCGGGCAGAGCAAGGCCGTGGGCCAGGATACCCTGCTGCGCTCGCTCCTGGAGACCAACGAAATCCCCTCG
CTTATCCTGTGGGGGCCGCCGGGCTGCGGCAAGGCCAAATTTGAGTTTCATCATGGTGACTATGAAAAACAGTTTCTGCATGTACTGAGC
CGCAAGGACAAGACTGGAATCGTTGTCAACAATCCTAACCAGTCAGTGTTTCTCTTCATTGACAGACAGCACTTGCAGACTCCAAAAAAC
AAAGCTACAATCTTCAAGTTATGCAGCATCTGCCTCTACCTGCCACAGGAACAGCTCACCCACTGGGCAGTTGGCACCATAGAGGATCAC
CTCCGTCCTTATATGCCAGAGTAGAGTACTGACCAGCAAAATGGAGAAGATCAGAGAATGCAGCAGCAGTTTTTTTTCTTGTTTTCTTAC
CACTTTATTCTTTCAGAGTTTAAAGAAAATGGACTCATGCACAGAACACTATGCATTTTGAAACTTGTTCATCCTGGATTTTTTTAAATC

>99401_99401_3_WRNIP1-C6orf62_WRNIP1_chr6_2766678_ENST00000380769_C6orf62_chr6_24709139_ENST00000540769_length(amino acids)=148AA_BP=62
MAAEEIRQMLQGKPLADTMRPDTLQDYFGQSKAVGQDTLLRSLLETNEIPSLILWGPPGCGKAKFEFHHGDYEKQFLHVLSRKDKTGIVV

--------------------------------------------------------------
>99401_99401_4_WRNIP1-C6orf62_WRNIP1_chr6_2766678_ENST00000380771_C6orf62_chr6_24709139_ENST00000378102_length(transcript)=1333nt_BP=1031nt
GAGGCGCTGCCAGCGGCCGGCCGAGGGCGGGCGGACGCGGGAGCTGCGGACGTGAGGCATGAGCGGCGCCCTCCTCCGGCCCGCGAGCGT
CCTGCTGGTTCCCCGAGCGAGGGTCTCGCGGCGCGGGGCCTAGCGGAGGGCATCGAAGGCCTCCGCGTGCGCACGGGTTGCTGCGGCCGC
GCCGGGCGCCGGGGAGGGCGGCGGCCGCCATGGAGGTGAGCGGGCCGGAAGACGACCCCTTCCTTTCGCAGCTGCACCAGGTGCAGTGCC
CCGTGTGCCAGCAGATGATGCCCGCCGCGCACATCAACTCGCACCTGGACCGCTGTCTGCTGCTCCACCCGGCGGGGCACGCGGAGCCCG
CGGCCGGGTCGCACCGCGCCGGGGAGCGGGCCAAGGGGCCCTCGCCGCCCGGCGCCAAGAGGCGGCGGCTGTCGGAGAGCTCGGCGCTGA
AGCAGCCAGCCACCCCGACGGCAGCCGAGAGCAGCGAGGGCGAGGGTGAGGAGGGCGACGACGGCGGCGAGACCGAGAGCCGCGAGAGCT
ACGACGCGCCGCCCACACCCAGCGGCGCCCGCCTTATCCCCGACTTCCCGGTGGCCCGCTCCAGCAGCCCCGGGAGGAAGGGGTCGGGGA
AGAGGCCGGCGGCCGCCGCCGCGGCGGGGAGCGCGTCTCCGCGCAGCTGGGACGAGGCGGAGGCGCAGGAGGAGGAGGAGGCCGTGGGCG
ACGGCGATGGCGACGGGGACGCGGACGCGGACGGCGAGGACGACCCGGGGCACTGGGACGCGGACGCTGCCGAAGCCGCCACCGCCTTCG
GGGCCAGTGGCGGGGGCCGCCCGCACCCCCGGGCGCTGGCTGCCGAGGAGATCCGACAGATGCTACAGGGCAAGCCGCTGGCCGACACGA
TGCGTCCTGACACGCTGCAGGATTACTTCGGGCAGAGCAAGGCCGTGGGCCAGGATACCCTGCTGCGCTCGCTCCTGGAGACCAACGAAA
TCCCCTCGCTTATCCTGTGGGGGCCGCCGGGCTGCGGCAAGGCCAAATTTGAGTTTCATCATGGTGACTATGAAAAACAGTTTCTGCATG
TACTGAGCCGCAAGGACAAGACTGGAATCGTTGTCAACAATCCTAACCAGTCAGTGTTTCTCTTCATTGACAGACAGCACTTGCAGACTC
CAAAAAACAAAGCTACAATCTTCAAGTTATGCAGCATCTGCCTCTACCTGCCACAGGAACAGCTCACCCACTGGGCAGTTGGCACCATAG

>99401_99401_4_WRNIP1-C6orf62_WRNIP1_chr6_2766678_ENST00000380771_C6orf62_chr6_24709139_ENST00000378102_length(amino acids)=374AA_BP=288
MLRPRRAPGRAAAAMEVSGPEDDPFLSQLHQVQCPVCQQMMPAAHINSHLDRCLLLHPAGHAEPAAGSHRAGERAKGPSPPGAKRRRLSE
SSALKQPATPTAAESSEGEGEEGDDGGETESRESYDAPPTPSGARLIPDFPVARSSSPGRKGSGKRPAAAAAAGSASPRSWDEAEAQEEE
EAVGDGDGDGDADADGEDDPGHWDADAAEAATAFGASGGGRPHPRALAAEEIRQMLQGKPLADTMRPDTLQDYFGQSKAVGQDTLLRSLL
ETNEIPSLILWGPPGCGKAKFEFHHGDYEKQFLHVLSRKDKTGIVVNNPNQSVFLFIDRQHLQTPKNKATIFKLCSICLYLPQEQLTHWA

--------------------------------------------------------------
>99401_99401_5_WRNIP1-C6orf62_WRNIP1_chr6_2766678_ENST00000380771_C6orf62_chr6_24709139_ENST00000378119_length(transcript)=2568nt_BP=1031nt
GAGGCGCTGCCAGCGGCCGGCCGAGGGCGGGCGGACGCGGGAGCTGCGGACGTGAGGCATGAGCGGCGCCCTCCTCCGGCCCGCGAGCGT
CCTGCTGGTTCCCCGAGCGAGGGTCTCGCGGCGCGGGGCCTAGCGGAGGGCATCGAAGGCCTCCGCGTGCGCACGGGTTGCTGCGGCCGC
GCCGGGCGCCGGGGAGGGCGGCGGCCGCCATGGAGGTGAGCGGGCCGGAAGACGACCCCTTCCTTTCGCAGCTGCACCAGGTGCAGTGCC
CCGTGTGCCAGCAGATGATGCCCGCCGCGCACATCAACTCGCACCTGGACCGCTGTCTGCTGCTCCACCCGGCGGGGCACGCGGAGCCCG
CGGCCGGGTCGCACCGCGCCGGGGAGCGGGCCAAGGGGCCCTCGCCGCCCGGCGCCAAGAGGCGGCGGCTGTCGGAGAGCTCGGCGCTGA
AGCAGCCAGCCACCCCGACGGCAGCCGAGAGCAGCGAGGGCGAGGGTGAGGAGGGCGACGACGGCGGCGAGACCGAGAGCCGCGAGAGCT
ACGACGCGCCGCCCACACCCAGCGGCGCCCGCCTTATCCCCGACTTCCCGGTGGCCCGCTCCAGCAGCCCCGGGAGGAAGGGGTCGGGGA
AGAGGCCGGCGGCCGCCGCCGCGGCGGGGAGCGCGTCTCCGCGCAGCTGGGACGAGGCGGAGGCGCAGGAGGAGGAGGAGGCCGTGGGCG
ACGGCGATGGCGACGGGGACGCGGACGCGGACGGCGAGGACGACCCGGGGCACTGGGACGCGGACGCTGCCGAAGCCGCCACCGCCTTCG
GGGCCAGTGGCGGGGGCCGCCCGCACCCCCGGGCGCTGGCTGCCGAGGAGATCCGACAGATGCTACAGGGCAAGCCGCTGGCCGACACGA
TGCGTCCTGACACGCTGCAGGATTACTTCGGGCAGAGCAAGGCCGTGGGCCAGGATACCCTGCTGCGCTCGCTCCTGGAGACCAACGAAA
TCCCCTCGCTTATCCTGTGGGGGCCGCCGGGCTGCGGCAAGGCCAAATTTGAGTTTCATCATGGTGACTATGAAAAACAGTTTCTGCATG
TACTGAGCCGCAAGGACAAGACTGGAATCGTTGTCAACAATCCTAACCAGTCAGTGTTTCTCTTCATTGACAGACAGCACTTGCAGACTC
CAAAAAACAAAGCTACAATCTTCAAGTTATGCAGCATCTGCCTCTACCTGCCACAGGAACAGCTCACCCACTGGGCAGTTGGCACCATAG
AGGATCACCTCCGTCCTTATATGCCAGAGTAGAGTACTGACCAGCAAAATGGAGAAGATCAGAGAATGCAGCAGCAGTTTTTTTTCTTGT
TTTCTTACCACTTTATTCTTTCAGAGTTTAAAGAAAATGGACTCATGCACAGAACACTATGCATTTTGAAACTTGTTCATCCTGGATTTT
TTTAAATCATTTTTATCTCAGAACTTAAACAAAAATTAGATGTCGTGCACGGACTGTGTGAAAGAAGATGCTTTGCATATTTGCTGCACT
GCATCAGTATCTTACTAAAAATGTGAAATGAAAGGACTATTGTACACTGAAATGCTTAAATGTATCTGAAAGCACAAGGTGATACTCATT
TTTATGGTCTTCCCATTTGTGCTGGTTTTTGCCTCTTTGACATCTGTCATCAGTATTTAGAGGGTGAGAAGTGAATGTAACAGGTATAAA
TAACATTTTTAAAAACAATAACTTTGCTATAATCACAGTTGTTCCAGAGCACTGTCAGATACATTCTAATGACCAGAACTGGTTTAAAAA
AAGAAAATACAACCATGGGAAAGAAATCTTAAATGAAAAACGCATCTCATTGTAGGCATTTTTGCCTCATATTTTACTGGGCCATGTTTG
TTTCCTGGTACTCATGTATTTTTTTTTTCCAGATCTCTTTCCCCAAGTTGCTATTGTAAGAGTATTCTGCTGCGTGTGGATGCAGTTATA
CACATTAAAGCAGATCTGGAGTCTGAAGTAGCTATAAAGCAGCTATAAAACAGAAATACATGCATAGCTGCAGAAACCATGATAGGTAGA
GGACTTTTCTTTTGGTTTTGTTTTGTTTTGTTTTGTTTTGTTTTTGGTTTTACAGAGAAGAGATTTTTATTACAAAGAAAAAAATTCCAG
TGAATTGTGCAGAAATGCTGGTTTTTACACCATCCTAAAGAAAAACTTTACAAGGGTGTTTTGGAGTAGAAAAAAGGTTATAAAGTTGGA
ATCTTAAATTGTAAAATTAACCATTGAGTGTCAAAGTTCTAAAAGCAGAACTCATTTTGTGCAATGAACATAAGGAAAGACTACTGTATA
GGTTTTTTTTTTTTTCTCCTTTTAAATGAAGAAAAGCTTTGCTTAAGGGTTGCATACTTTTATTGGAGTAAATCTGAATGATCCTACTCC
TTTGGAGTAAAACTAGTGCTTACCAGTTTCCAATTGTATTTAGCTTCTGGTTGGAATTTGAAAAAAAAAGAAAAAAAGAAAAAGAAAACC

>99401_99401_5_WRNIP1-C6orf62_WRNIP1_chr6_2766678_ENST00000380771_C6orf62_chr6_24709139_ENST00000378119_length(amino acids)=374AA_BP=288
MLRPRRAPGRAAAAMEVSGPEDDPFLSQLHQVQCPVCQQMMPAAHINSHLDRCLLLHPAGHAEPAAGSHRAGERAKGPSPPGAKRRRLSE
SSALKQPATPTAAESSEGEGEEGDDGGETESRESYDAPPTPSGARLIPDFPVARSSSPGRKGSGKRPAAAAAAGSASPRSWDEAEAQEEE
EAVGDGDGDGDADADGEDDPGHWDADAAEAATAFGASGGGRPHPRALAAEEIRQMLQGKPLADTMRPDTLQDYFGQSKAVGQDTLLRSLL
ETNEIPSLILWGPPGCGKAKFEFHHGDYEKQFLHVLSRKDKTGIVVNNPNQSVFLFIDRQHLQTPKNKATIFKLCSICLYLPQEQLTHWA

--------------------------------------------------------------
>99401_99401_6_WRNIP1-C6orf62_WRNIP1_chr6_2766678_ENST00000380771_C6orf62_chr6_24709139_ENST00000540769_length(transcript)=1505nt_BP=1031nt
GAGGCGCTGCCAGCGGCCGGCCGAGGGCGGGCGGACGCGGGAGCTGCGGACGTGAGGCATGAGCGGCGCCCTCCTCCGGCCCGCGAGCGT
CCTGCTGGTTCCCCGAGCGAGGGTCTCGCGGCGCGGGGCCTAGCGGAGGGCATCGAAGGCCTCCGCGTGCGCACGGGTTGCTGCGGCCGC
GCCGGGCGCCGGGGAGGGCGGCGGCCGCCATGGAGGTGAGCGGGCCGGAAGACGACCCCTTCCTTTCGCAGCTGCACCAGGTGCAGTGCC
CCGTGTGCCAGCAGATGATGCCCGCCGCGCACATCAACTCGCACCTGGACCGCTGTCTGCTGCTCCACCCGGCGGGGCACGCGGAGCCCG
CGGCCGGGTCGCACCGCGCCGGGGAGCGGGCCAAGGGGCCCTCGCCGCCCGGCGCCAAGAGGCGGCGGCTGTCGGAGAGCTCGGCGCTGA
AGCAGCCAGCCACCCCGACGGCAGCCGAGAGCAGCGAGGGCGAGGGTGAGGAGGGCGACGACGGCGGCGAGACCGAGAGCCGCGAGAGCT
ACGACGCGCCGCCCACACCCAGCGGCGCCCGCCTTATCCCCGACTTCCCGGTGGCCCGCTCCAGCAGCCCCGGGAGGAAGGGGTCGGGGA
AGAGGCCGGCGGCCGCCGCCGCGGCGGGGAGCGCGTCTCCGCGCAGCTGGGACGAGGCGGAGGCGCAGGAGGAGGAGGAGGCCGTGGGCG
ACGGCGATGGCGACGGGGACGCGGACGCGGACGGCGAGGACGACCCGGGGCACTGGGACGCGGACGCTGCCGAAGCCGCCACCGCCTTCG
GGGCCAGTGGCGGGGGCCGCCCGCACCCCCGGGCGCTGGCTGCCGAGGAGATCCGACAGATGCTACAGGGCAAGCCGCTGGCCGACACGA
TGCGTCCTGACACGCTGCAGGATTACTTCGGGCAGAGCAAGGCCGTGGGCCAGGATACCCTGCTGCGCTCGCTCCTGGAGACCAACGAAA
TCCCCTCGCTTATCCTGTGGGGGCCGCCGGGCTGCGGCAAGGCCAAATTTGAGTTTCATCATGGTGACTATGAAAAACAGTTTCTGCATG
TACTGAGCCGCAAGGACAAGACTGGAATCGTTGTCAACAATCCTAACCAGTCAGTGTTTCTCTTCATTGACAGACAGCACTTGCAGACTC
CAAAAAACAAAGCTACAATCTTCAAGTTATGCAGCATCTGCCTCTACCTGCCACAGGAACAGCTCACCCACTGGGCAGTTGGCACCATAG
AGGATCACCTCCGTCCTTATATGCCAGAGTAGAGTACTGACCAGCAAAATGGAGAAGATCAGAGAATGCAGCAGCAGTTTTTTTTCTTGT
TTTCTTACCACTTTATTCTTTCAGAGTTTAAAGAAAATGGACTCATGCACAGAACACTATGCATTTTGAAACTTGTTCATCCTGGATTTT

>99401_99401_6_WRNIP1-C6orf62_WRNIP1_chr6_2766678_ENST00000380771_C6orf62_chr6_24709139_ENST00000540769_length(amino acids)=374AA_BP=288
MLRPRRAPGRAAAAMEVSGPEDDPFLSQLHQVQCPVCQQMMPAAHINSHLDRCLLLHPAGHAEPAAGSHRAGERAKGPSPPGAKRRRLSE
SSALKQPATPTAAESSEGEGEEGDDGGETESRESYDAPPTPSGARLIPDFPVARSSSPGRKGSGKRPAAAAAAGSASPRSWDEAEAQEEE
EAVGDGDGDGDADADGEDDPGHWDADAAEAATAFGASGGGRPHPRALAAEEIRQMLQGKPLADTMRPDTLQDYFGQSKAVGQDTLLRSLL
ETNEIPSLILWGPPGCGKAKFEFHHGDYEKQFLHVLSRKDKTGIVVNNPNQSVFLFIDRQHLQTPKNKATIFKLCSICLYLPQEQLTHWA

--------------------------------------------------------------
>99401_99401_7_WRNIP1-C6orf62_WRNIP1_chr6_2766678_ENST00000380773_C6orf62_chr6_24709139_ENST00000378102_length(transcript)=1333nt_BP=1031nt
GAGGCGCTGCCAGCGGCCGGCCGAGGGCGGGCGGACGCGGGAGCTGCGGACGTGAGGCATGAGCGGCGCCCTCCTCCGGCCCGCGAGCGT
CCTGCTGGTTCCCCGAGCGAGGGTCTCGCGGCGCGGGGCCTAGCGGAGGGCATCGAAGGCCTCCGCGTGCGCACGGGTTGCTGCGGCCGC
GCCGGGCGCCGGGGAGGGCGGCGGCCGCCATGGAGGTGAGCGGGCCGGAAGACGACCCCTTCCTTTCGCAGCTGCACCAGGTGCAGTGCC
CCGTGTGCCAGCAGATGATGCCCGCCGCGCACATCAACTCGCACCTGGACCGCTGTCTGCTGCTCCACCCGGCGGGGCACGCGGAGCCCG
CGGCCGGGTCGCACCGCGCCGGGGAGCGGGCCAAGGGGCCCTCGCCGCCCGGCGCCAAGAGGCGGCGGCTGTCGGAGAGCTCGGCGCTGA
AGCAGCCAGCCACCCCGACGGCAGCCGAGAGCAGCGAGGGCGAGGGTGAGGAGGGCGACGACGGCGGCGAGACCGAGAGCCGCGAGAGCT
ACGACGCGCCGCCCACACCCAGCGGCGCCCGCCTTATCCCCGACTTCCCGGTGGCCCGCTCCAGCAGCCCCGGGAGGAAGGGGTCGGGGA
AGAGGCCGGCGGCCGCCGCCGCGGCGGGGAGCGCGTCTCCGCGCAGCTGGGACGAGGCGGAGGCGCAGGAGGAGGAGGAGGCCGTGGGCG
ACGGCGATGGCGACGGGGACGCGGACGCGGACGGCGAGGACGACCCGGGGCACTGGGACGCGGACGCTGCCGAAGCCGCCACCGCCTTCG
GGGCCAGTGGCGGGGGCCGCCCGCACCCCCGGGCGCTGGCTGCCGAGGAGATCCGACAGATGCTACAGGGCAAGCCGCTGGCCGACACGA
TGCGTCCTGACACGCTGCAGGATTACTTCGGGCAGAGCAAGGCCGTGGGCCAGGATACCCTGCTGCGCTCGCTCCTGGAGACCAACGAAA
TCCCCTCGCTTATCCTGTGGGGGCCGCCGGGCTGCGGCAAGGCCAAATTTGAGTTTCATCATGGTGACTATGAAAAACAGTTTCTGCATG
TACTGAGCCGCAAGGACAAGACTGGAATCGTTGTCAACAATCCTAACCAGTCAGTGTTTCTCTTCATTGACAGACAGCACTTGCAGACTC
CAAAAAACAAAGCTACAATCTTCAAGTTATGCAGCATCTGCCTCTACCTGCCACAGGAACAGCTCACCCACTGGGCAGTTGGCACCATAG

>99401_99401_7_WRNIP1-C6orf62_WRNIP1_chr6_2766678_ENST00000380773_C6orf62_chr6_24709139_ENST00000378102_length(amino acids)=374AA_BP=288
MLRPRRAPGRAAAAMEVSGPEDDPFLSQLHQVQCPVCQQMMPAAHINSHLDRCLLLHPAGHAEPAAGSHRAGERAKGPSPPGAKRRRLSE
SSALKQPATPTAAESSEGEGEEGDDGGETESRESYDAPPTPSGARLIPDFPVARSSSPGRKGSGKRPAAAAAAGSASPRSWDEAEAQEEE
EAVGDGDGDGDADADGEDDPGHWDADAAEAATAFGASGGGRPHPRALAAEEIRQMLQGKPLADTMRPDTLQDYFGQSKAVGQDTLLRSLL
ETNEIPSLILWGPPGCGKAKFEFHHGDYEKQFLHVLSRKDKTGIVVNNPNQSVFLFIDRQHLQTPKNKATIFKLCSICLYLPQEQLTHWA

--------------------------------------------------------------
>99401_99401_8_WRNIP1-C6orf62_WRNIP1_chr6_2766678_ENST00000380773_C6orf62_chr6_24709139_ENST00000378119_length(transcript)=2568nt_BP=1031nt
GAGGCGCTGCCAGCGGCCGGCCGAGGGCGGGCGGACGCGGGAGCTGCGGACGTGAGGCATGAGCGGCGCCCTCCTCCGGCCCGCGAGCGT
CCTGCTGGTTCCCCGAGCGAGGGTCTCGCGGCGCGGGGCCTAGCGGAGGGCATCGAAGGCCTCCGCGTGCGCACGGGTTGCTGCGGCCGC
GCCGGGCGCCGGGGAGGGCGGCGGCCGCCATGGAGGTGAGCGGGCCGGAAGACGACCCCTTCCTTTCGCAGCTGCACCAGGTGCAGTGCC
CCGTGTGCCAGCAGATGATGCCCGCCGCGCACATCAACTCGCACCTGGACCGCTGTCTGCTGCTCCACCCGGCGGGGCACGCGGAGCCCG
CGGCCGGGTCGCACCGCGCCGGGGAGCGGGCCAAGGGGCCCTCGCCGCCCGGCGCCAAGAGGCGGCGGCTGTCGGAGAGCTCGGCGCTGA
AGCAGCCAGCCACCCCGACGGCAGCCGAGAGCAGCGAGGGCGAGGGTGAGGAGGGCGACGACGGCGGCGAGACCGAGAGCCGCGAGAGCT
ACGACGCGCCGCCCACACCCAGCGGCGCCCGCCTTATCCCCGACTTCCCGGTGGCCCGCTCCAGCAGCCCCGGGAGGAAGGGGTCGGGGA
AGAGGCCGGCGGCCGCCGCCGCGGCGGGGAGCGCGTCTCCGCGCAGCTGGGACGAGGCGGAGGCGCAGGAGGAGGAGGAGGCCGTGGGCG
ACGGCGATGGCGACGGGGACGCGGACGCGGACGGCGAGGACGACCCGGGGCACTGGGACGCGGACGCTGCCGAAGCCGCCACCGCCTTCG
GGGCCAGTGGCGGGGGCCGCCCGCACCCCCGGGCGCTGGCTGCCGAGGAGATCCGACAGATGCTACAGGGCAAGCCGCTGGCCGACACGA
TGCGTCCTGACACGCTGCAGGATTACTTCGGGCAGAGCAAGGCCGTGGGCCAGGATACCCTGCTGCGCTCGCTCCTGGAGACCAACGAAA
TCCCCTCGCTTATCCTGTGGGGGCCGCCGGGCTGCGGCAAGGCCAAATTTGAGTTTCATCATGGTGACTATGAAAAACAGTTTCTGCATG
TACTGAGCCGCAAGGACAAGACTGGAATCGTTGTCAACAATCCTAACCAGTCAGTGTTTCTCTTCATTGACAGACAGCACTTGCAGACTC
CAAAAAACAAAGCTACAATCTTCAAGTTATGCAGCATCTGCCTCTACCTGCCACAGGAACAGCTCACCCACTGGGCAGTTGGCACCATAG
AGGATCACCTCCGTCCTTATATGCCAGAGTAGAGTACTGACCAGCAAAATGGAGAAGATCAGAGAATGCAGCAGCAGTTTTTTTTCTTGT
TTTCTTACCACTTTATTCTTTCAGAGTTTAAAGAAAATGGACTCATGCACAGAACACTATGCATTTTGAAACTTGTTCATCCTGGATTTT
TTTAAATCATTTTTATCTCAGAACTTAAACAAAAATTAGATGTCGTGCACGGACTGTGTGAAAGAAGATGCTTTGCATATTTGCTGCACT
GCATCAGTATCTTACTAAAAATGTGAAATGAAAGGACTATTGTACACTGAAATGCTTAAATGTATCTGAAAGCACAAGGTGATACTCATT
TTTATGGTCTTCCCATTTGTGCTGGTTTTTGCCTCTTTGACATCTGTCATCAGTATTTAGAGGGTGAGAAGTGAATGTAACAGGTATAAA
TAACATTTTTAAAAACAATAACTTTGCTATAATCACAGTTGTTCCAGAGCACTGTCAGATACATTCTAATGACCAGAACTGGTTTAAAAA
AAGAAAATACAACCATGGGAAAGAAATCTTAAATGAAAAACGCATCTCATTGTAGGCATTTTTGCCTCATATTTTACTGGGCCATGTTTG
TTTCCTGGTACTCATGTATTTTTTTTTTCCAGATCTCTTTCCCCAAGTTGCTATTGTAAGAGTATTCTGCTGCGTGTGGATGCAGTTATA
CACATTAAAGCAGATCTGGAGTCTGAAGTAGCTATAAAGCAGCTATAAAACAGAAATACATGCATAGCTGCAGAAACCATGATAGGTAGA
GGACTTTTCTTTTGGTTTTGTTTTGTTTTGTTTTGTTTTGTTTTTGGTTTTACAGAGAAGAGATTTTTATTACAAAGAAAAAAATTCCAG
TGAATTGTGCAGAAATGCTGGTTTTTACACCATCCTAAAGAAAAACTTTACAAGGGTGTTTTGGAGTAGAAAAAAGGTTATAAAGTTGGA
ATCTTAAATTGTAAAATTAACCATTGAGTGTCAAAGTTCTAAAAGCAGAACTCATTTTGTGCAATGAACATAAGGAAAGACTACTGTATA
GGTTTTTTTTTTTTTCTCCTTTTAAATGAAGAAAAGCTTTGCTTAAGGGTTGCATACTTTTATTGGAGTAAATCTGAATGATCCTACTCC
TTTGGAGTAAAACTAGTGCTTACCAGTTTCCAATTGTATTTAGCTTCTGGTTGGAATTTGAAAAAAAAAGAAAAAAAGAAAAAGAAAACC

>99401_99401_8_WRNIP1-C6orf62_WRNIP1_chr6_2766678_ENST00000380773_C6orf62_chr6_24709139_ENST00000378119_length(amino acids)=374AA_BP=288
MLRPRRAPGRAAAAMEVSGPEDDPFLSQLHQVQCPVCQQMMPAAHINSHLDRCLLLHPAGHAEPAAGSHRAGERAKGPSPPGAKRRRLSE
SSALKQPATPTAAESSEGEGEEGDDGGETESRESYDAPPTPSGARLIPDFPVARSSSPGRKGSGKRPAAAAAAGSASPRSWDEAEAQEEE
EAVGDGDGDGDADADGEDDPGHWDADAAEAATAFGASGGGRPHPRALAAEEIRQMLQGKPLADTMRPDTLQDYFGQSKAVGQDTLLRSLL
ETNEIPSLILWGPPGCGKAKFEFHHGDYEKQFLHVLSRKDKTGIVVNNPNQSVFLFIDRQHLQTPKNKATIFKLCSICLYLPQEQLTHWA

--------------------------------------------------------------
>99401_99401_9_WRNIP1-C6orf62_WRNIP1_chr6_2766678_ENST00000380773_C6orf62_chr6_24709139_ENST00000540769_length(transcript)=1505nt_BP=1031nt
GAGGCGCTGCCAGCGGCCGGCCGAGGGCGGGCGGACGCGGGAGCTGCGGACGTGAGGCATGAGCGGCGCCCTCCTCCGGCCCGCGAGCGT
CCTGCTGGTTCCCCGAGCGAGGGTCTCGCGGCGCGGGGCCTAGCGGAGGGCATCGAAGGCCTCCGCGTGCGCACGGGTTGCTGCGGCCGC
GCCGGGCGCCGGGGAGGGCGGCGGCCGCCATGGAGGTGAGCGGGCCGGAAGACGACCCCTTCCTTTCGCAGCTGCACCAGGTGCAGTGCC
CCGTGTGCCAGCAGATGATGCCCGCCGCGCACATCAACTCGCACCTGGACCGCTGTCTGCTGCTCCACCCGGCGGGGCACGCGGAGCCCG
CGGCCGGGTCGCACCGCGCCGGGGAGCGGGCCAAGGGGCCCTCGCCGCCCGGCGCCAAGAGGCGGCGGCTGTCGGAGAGCTCGGCGCTGA
AGCAGCCAGCCACCCCGACGGCAGCCGAGAGCAGCGAGGGCGAGGGTGAGGAGGGCGACGACGGCGGCGAGACCGAGAGCCGCGAGAGCT
ACGACGCGCCGCCCACACCCAGCGGCGCCCGCCTTATCCCCGACTTCCCGGTGGCCCGCTCCAGCAGCCCCGGGAGGAAGGGGTCGGGGA
AGAGGCCGGCGGCCGCCGCCGCGGCGGGGAGCGCGTCTCCGCGCAGCTGGGACGAGGCGGAGGCGCAGGAGGAGGAGGAGGCCGTGGGCG
ACGGCGATGGCGACGGGGACGCGGACGCGGACGGCGAGGACGACCCGGGGCACTGGGACGCGGACGCTGCCGAAGCCGCCACCGCCTTCG
GGGCCAGTGGCGGGGGCCGCCCGCACCCCCGGGCGCTGGCTGCCGAGGAGATCCGACAGATGCTACAGGGCAAGCCGCTGGCCGACACGA
TGCGTCCTGACACGCTGCAGGATTACTTCGGGCAGAGCAAGGCCGTGGGCCAGGATACCCTGCTGCGCTCGCTCCTGGAGACCAACGAAA
TCCCCTCGCTTATCCTGTGGGGGCCGCCGGGCTGCGGCAAGGCCAAATTTGAGTTTCATCATGGTGACTATGAAAAACAGTTTCTGCATG
TACTGAGCCGCAAGGACAAGACTGGAATCGTTGTCAACAATCCTAACCAGTCAGTGTTTCTCTTCATTGACAGACAGCACTTGCAGACTC
CAAAAAACAAAGCTACAATCTTCAAGTTATGCAGCATCTGCCTCTACCTGCCACAGGAACAGCTCACCCACTGGGCAGTTGGCACCATAG
AGGATCACCTCCGTCCTTATATGCCAGAGTAGAGTACTGACCAGCAAAATGGAGAAGATCAGAGAATGCAGCAGCAGTTTTTTTTCTTGT
TTTCTTACCACTTTATTCTTTCAGAGTTTAAAGAAAATGGACTCATGCACAGAACACTATGCATTTTGAAACTTGTTCATCCTGGATTTT

>99401_99401_9_WRNIP1-C6orf62_WRNIP1_chr6_2766678_ENST00000380773_C6orf62_chr6_24709139_ENST00000540769_length(amino acids)=374AA_BP=288
MLRPRRAPGRAAAAMEVSGPEDDPFLSQLHQVQCPVCQQMMPAAHINSHLDRCLLLHPAGHAEPAAGSHRAGERAKGPSPPGAKRRRLSE
SSALKQPATPTAAESSEGEGEEGDDGGETESRESYDAPPTPSGARLIPDFPVARSSSPGRKGSGKRPAAAAAAGSASPRSWDEAEAQEEE
EAVGDGDGDGDADADGEDDPGHWDADAAEAATAFGASGGGRPHPRALAAEEIRQMLQGKPLADTMRPDTLQDYFGQSKAVGQDTLLRSLL
ETNEIPSLILWGPPGCGKAKFEFHHGDYEKQFLHVLSRKDKTGIVVNNPNQSVFLFIDRQHLQTPKNKATIFKLCSICLYLPQEQLTHWA

--------------------------------------------------------------

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Fusion Gene PPI Analysis for WRNIP1-C6orf62


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for WRNIP1-C6orf62


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for WRNIP1-C6orf62


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource