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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:WWP2-TANGO6 (FusionGDB2 ID:99536)

Fusion Gene Summary for WWP2-TANGO6

check button Fusion gene summary
Fusion gene informationFusion gene name: WWP2-TANGO6
Fusion gene ID: 99536
HgeneTgene
Gene symbol

WWP2

TANGO6

Gene ID

11060

79613

Gene nameWW domain containing E3 ubiquitin protein ligase 2transport and golgi organization 6 homolog
SynonymsAIP2|WWp2-likeTMCO7
Cytomap

16q22.1

16q22.1

Type of geneprotein-codingprotein-coding
DescriptionNEDD4-like E3 ubiquitin-protein ligase WWP2HECT-type E3 ubiquitin transferase WWP2atrophin-1 interacting protein 2transport and Golgi organization protein 6 homologtransmembrane and coiled-coil domain-containing protein 7transmembrane and coiled-coil domains 7
Modification date2020032720200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000544162, ENST00000356003, 
ENST00000359154, ENST00000448661, 
ENST00000542271, ENST00000569174, 
ENST00000568684, 		ENST00000261778, 
ENST00000561931, 
Fusion gene scores* DoF score18 X 16 X 11=316812 X 15 X 6=1080
# samples 2318
** MAII scorelog2(23/3168*10)=-3.78386656913523
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(18/1080*10)=-2.58496250072116
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: WWP2 [Title/Abstract] AND TANGO6 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointTANGO6(69008071)-WWP2(69905707), # samples:1
WWP2(69922152)-TANGO6(68936231), # samples:2
WWP2(69820983)-TANGO6(69007931), # samples:2
WWP2(69876023)-TANGO6(69056731), # samples:2
Anticipated loss of major functional domain due to fusion event.TANGO6-WWP2 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
TANGO6-WWP2 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
WWP2-TANGO6 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
WWP2-TANGO6 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneWWP2

GO:0016567

protein ubiquitination

18776082|26280536

HgeneWWP2

GO:0032410

negative regulation of transporter activity

18776082

HgeneWWP2

GO:0034765

regulation of ion transmembrane transport

17289006

HgeneWWP2

GO:0042391

regulation of membrane potential

17289006

HgeneWWP2

GO:0051865

protein autoubiquitination

24105792

HgeneWWP2

GO:1901016

regulation of potassium ion transmembrane transporter activity

17289006


check buttonFusion gene breakpoints across WWP2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across TANGO6 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUSCTCGA-94-7557-01AWWP2chr16

69922152

+TANGO6chr16

68936231

+
ChimerDB4LUSCTCGA-94-7557WWP2chr16

69922152

+TANGO6chr16

68936231

+
ChimerDB4LUSCTCGA-94-7557WWP2chr16

69922152

+TANGO6chr16

68941346

+
ChimerDB4LUSCTCGA-94-7557WWP2chr16

69985026

+TANGO6chr16

68936230

+
ChimerDB4OVTCGA-24-2026-01AWWP2chr16

69820983

+TANGO6chr16

69007931

+
ChimerDB4UCECTCGA-AX-A3FV-01AWWP2chr16

69876023

+TANGO6chr16

69056731

+


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Fusion Gene ORF analysis for WWP2-TANGO6

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000544162ENST00000261778WWP2chr16

69922152

+TANGO6chr16

68936231

+
3UTR-3CDSENST00000544162ENST00000261778WWP2chr16

69922152

+TANGO6chr16

68941346

+
3UTR-3CDSENST00000544162ENST00000261778WWP2chr16

69876023

+TANGO6chr16

69056731

+
3UTR-intronENST00000544162ENST00000561931WWP2chr16

69922152

+TANGO6chr16

68936231

+
3UTR-intronENST00000544162ENST00000561931WWP2chr16

69922152

+TANGO6chr16

68941346

+
3UTR-intronENST00000544162ENST00000561931WWP2chr16

69876023

+TANGO6chr16

69056731

+
5CDS-intronENST00000356003ENST00000561931WWP2chr16

69922152

+TANGO6chr16

68936231

+
5CDS-intronENST00000356003ENST00000561931WWP2chr16

69922152

+TANGO6chr16

68941346

+
5CDS-intronENST00000356003ENST00000561931WWP2chr16

69820983

+TANGO6chr16

69007931

+
5CDS-intronENST00000356003ENST00000561931WWP2chr16

69876023

+TANGO6chr16

69056731

+
5CDS-intronENST00000359154ENST00000561931WWP2chr16

69922152

+TANGO6chr16

68936231

+
5CDS-intronENST00000359154ENST00000561931WWP2chr16

69922152

+TANGO6chr16

68941346

+
5CDS-intronENST00000359154ENST00000561931WWP2chr16

69820983

+TANGO6chr16

69007931

+
5CDS-intronENST00000359154ENST00000561931WWP2chr16

69876023

+TANGO6chr16

69056731

+
5CDS-intronENST00000448661ENST00000561931WWP2chr16

69922152

+TANGO6chr16

68936231

+
5CDS-intronENST00000448661ENST00000561931WWP2chr16

69922152

+TANGO6chr16

68941346

+
5CDS-intronENST00000448661ENST00000561931WWP2chr16

69820983

+TANGO6chr16

69007931

+
5CDS-intronENST00000448661ENST00000561931WWP2chr16

69876023

+TANGO6chr16

69056731

+
5CDS-intronENST00000542271ENST00000561931WWP2chr16

69922152

+TANGO6chr16

68936231

+
5CDS-intronENST00000542271ENST00000561931WWP2chr16

69922152

+TANGO6chr16

68941346

+
5CDS-intronENST00000542271ENST00000561931WWP2chr16

69876023

+TANGO6chr16

69056731

+
5CDS-intronENST00000569174ENST00000561931WWP2chr16

69922152

+TANGO6chr16

68936231

+
5CDS-intronENST00000569174ENST00000561931WWP2chr16

69922152

+TANGO6chr16

68941346

+
5CDS-intronENST00000569174ENST00000561931WWP2chr16

69820983

+TANGO6chr16

69007931

+
5CDS-intronENST00000569174ENST00000561931WWP2chr16

69876023

+TANGO6chr16

69056731

+
Frame-shiftENST00000356003ENST00000261778WWP2chr16

69876023

+TANGO6chr16

69056731

+
Frame-shiftENST00000359154ENST00000261778WWP2chr16

69876023

+TANGO6chr16

69056731

+
Frame-shiftENST00000448661ENST00000261778WWP2chr16

69876023

+TANGO6chr16

69056731

+
Frame-shiftENST00000542271ENST00000261778WWP2chr16

69876023

+TANGO6chr16

69056731

+
Frame-shiftENST00000569174ENST00000261778WWP2chr16

69876023

+TANGO6chr16

69056731

+
In-frameENST00000356003ENST00000261778WWP2chr16

69922152

+TANGO6chr16

68936231

+
In-frameENST00000356003ENST00000261778WWP2chr16

69922152

+TANGO6chr16

68941346

+
In-frameENST00000356003ENST00000261778WWP2chr16

69820983

+TANGO6chr16

69007931

+
In-frameENST00000359154ENST00000261778WWP2chr16

69922152

+TANGO6chr16

68936231

+
In-frameENST00000359154ENST00000261778WWP2chr16

69922152

+TANGO6chr16

68941346

+
In-frameENST00000359154ENST00000261778WWP2chr16

69820983

+TANGO6chr16

69007931

+
In-frameENST00000448661ENST00000261778WWP2chr16

69922152

+TANGO6chr16

68936231

+
In-frameENST00000448661ENST00000261778WWP2chr16

69922152

+TANGO6chr16

68941346

+
In-frameENST00000448661ENST00000261778WWP2chr16

69820983

+TANGO6chr16

69007931

+
In-frameENST00000542271ENST00000261778WWP2chr16

69922152

+TANGO6chr16

68936231

+
In-frameENST00000542271ENST00000261778WWP2chr16

69922152

+TANGO6chr16

68941346

+
In-frameENST00000569174ENST00000261778WWP2chr16

69922152

+TANGO6chr16

68936231

+
In-frameENST00000569174ENST00000261778WWP2chr16

69922152

+TANGO6chr16

68941346

+
In-frameENST00000569174ENST00000261778WWP2chr16

69820983

+TANGO6chr16

69007931

+
intron-3CDSENST00000356003ENST00000261778WWP2chr16

69985026

+TANGO6chr16

68936230

+
intron-3CDSENST00000359154ENST00000261778WWP2chr16

69985026

+TANGO6chr16

68936230

+
intron-3CDSENST00000448661ENST00000261778WWP2chr16

69985026

+TANGO6chr16

68936230

+
intron-3CDSENST00000542271ENST00000261778WWP2chr16

69985026

+TANGO6chr16

68936230

+
intron-3CDSENST00000542271ENST00000261778WWP2chr16

69820983

+TANGO6chr16

69007931

+
intron-3CDSENST00000544162ENST00000261778WWP2chr16

69985026

+TANGO6chr16

68936230

+
intron-3CDSENST00000544162ENST00000261778WWP2chr16

69820983

+TANGO6chr16

69007931

+
intron-3CDSENST00000568684ENST00000261778WWP2chr16

69922152

+TANGO6chr16

68936231

+
intron-3CDSENST00000568684ENST00000261778WWP2chr16

69922152

+TANGO6chr16

68941346

+
intron-3CDSENST00000568684ENST00000261778WWP2chr16

69985026

+TANGO6chr16

68936230

+
intron-3CDSENST00000568684ENST00000261778WWP2chr16

69820983

+TANGO6chr16

69007931

+
intron-3CDSENST00000568684ENST00000261778WWP2chr16

69876023

+TANGO6chr16

69056731

+
intron-3CDSENST00000569174ENST00000261778WWP2chr16

69985026

+TANGO6chr16

68936230

+
intron-intronENST00000356003ENST00000561931WWP2chr16

69985026

+TANGO6chr16

68936230

+
intron-intronENST00000359154ENST00000561931WWP2chr16

69985026

+TANGO6chr16

68936230

+
intron-intronENST00000448661ENST00000561931WWP2chr16

69985026

+TANGO6chr16

68936230

+
intron-intronENST00000542271ENST00000561931WWP2chr16

69985026

+TANGO6chr16

68936230

+
intron-intronENST00000542271ENST00000561931WWP2chr16

69820983

+TANGO6chr16

69007931

+
intron-intronENST00000544162ENST00000561931WWP2chr16

69985026

+TANGO6chr16

68936230

+
intron-intronENST00000544162ENST00000561931WWP2chr16

69820983

+TANGO6chr16

69007931

+
intron-intronENST00000568684ENST00000561931WWP2chr16

69922152

+TANGO6chr16

68936231

+
intron-intronENST00000568684ENST00000561931WWP2chr16

69922152

+TANGO6chr16

68941346

+
intron-intronENST00000568684ENST00000561931WWP2chr16

69985026

+TANGO6chr16

68936230

+
intron-intronENST00000568684ENST00000561931WWP2chr16

69820983

+TANGO6chr16

69007931

+
intron-intronENST00000568684ENST00000561931WWP2chr16

69876023

+TANGO6chr16

69056731

+
intron-intronENST00000569174ENST00000561931WWP2chr16

69985026

+TANGO6chr16

68936230

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000359154WWP2chr1669922152+ENST00000261778TANGO6chr1668936231+43291015712809912
ENST00000448661WWP2chr1669922152+ENST00000261778TANGO6chr1668936231+4306992782786902
ENST00000569174WWP2chr1669922152+ENST00000261778TANGO6chr1668936231+4298984702778902
ENST00000356003WWP2chr1669922152+ENST00000261778TANGO6chr1668936231+4254940262734902
ENST00000542271WWP2chr1669922152+ENST00000261778TANGO6chr1668936231+40417271612521786
ENST00000359154WWP2chr1669820983+ENST00000261778TANGO6chr1669007931+227417171754227
ENST00000448661WWP2chr1669820983+ENST00000261778TANGO6chr1669007931+225114878731217
ENST00000569174WWP2chr1669820983+ENST00000261778TANGO6chr1669007931+224314070723217
ENST00000356003WWP2chr1669820983+ENST00000261778TANGO6chr1669007931+21999626679217
ENST00000359154WWP2chr1669922152+ENST00000261778TANGO6chr1668941346+41521015712632853
ENST00000448661WWP2chr1669922152+ENST00000261778TANGO6chr1668941346+4129992782609843
ENST00000569174WWP2chr1669922152+ENST00000261778TANGO6chr1668941346+4121984702601843
ENST00000356003WWP2chr1669922152+ENST00000261778TANGO6chr1668941346+4077940262557843
ENST00000542271WWP2chr1669922152+ENST00000261778TANGO6chr1668941346+38647271612344727

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000359154ENST00000261778WWP2chr1669922152+TANGO6chr1668936231+0.0052137610.99478626
ENST00000448661ENST00000261778WWP2chr1669922152+TANGO6chr1668936231+0.0050129360.99498713
ENST00000569174ENST00000261778WWP2chr1669922152+TANGO6chr1668936231+0.0051013670.9948986
ENST00000356003ENST00000261778WWP2chr1669922152+TANGO6chr1668936231+0.0050438080.9949562
ENST00000542271ENST00000261778WWP2chr1669922152+TANGO6chr1668936231+0.0114416150.9885584
ENST00000359154ENST00000261778WWP2chr1669820983+TANGO6chr1669007931+0.0023378270.9976622
ENST00000448661ENST00000261778WWP2chr1669820983+TANGO6chr1669007931+0.0027048610.9972951
ENST00000569174ENST00000261778WWP2chr1669820983+TANGO6chr1669007931+0.0025832130.99741673
ENST00000356003ENST00000261778WWP2chr1669820983+TANGO6chr1669007931+0.0023507290.99764925
ENST00000359154ENST00000261778WWP2chr1669922152+TANGO6chr1668941346+0.0060379450.993962
ENST00000448661ENST00000261778WWP2chr1669922152+TANGO6chr1668941346+0.0057932750.99420667
ENST00000569174ENST00000261778WWP2chr1669922152+TANGO6chr1668941346+0.0059276660.9940724
ENST00000356003ENST00000261778WWP2chr1669922152+TANGO6chr1668941346+0.0058443530.99415565
ENST00000542271ENST00000261778WWP2chr1669922152+TANGO6chr1668941346+0.0118402550.9881598

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Fusion Genomic Features for WWP2-TANGO6


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
WWP2chr1669876023+TANGO6chr1669056730+2.44E-060.9999976
WWP2chr1669922152+TANGO6chr1668936230+3.49E-070.99999964
WWP2chr1669922152+TANGO6chr1668936230+3.49E-070.99999964
WWP2chr1669922152+TANGO6chr1668941345+1.80E-070.99999976
WWP2chr1669820983+TANGO6chr1669007930+3.10E-081
WWP2chr1669876023+TANGO6chr1669056730+2.44E-060.9999976
WWP2chr1669922152+TANGO6chr1668936230+3.49E-070.99999964
WWP2chr1669922152+TANGO6chr1668936230+3.49E-070.99999964
WWP2chr1669922152+TANGO6chr1668941345+1.80E-070.99999976
WWP2chr1669820983+TANGO6chr1669007930+3.10E-081

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for WWP2-TANGO6


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr16:69008071/chr16:69905707)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneWWP2chr16:69922152chr16:68936231ENST00000356003+7231_117304871.0DomainC2
HgeneWWP2chr16:69922152chr16:68936231ENST00000359154+8241_117304871.0DomainC2
HgeneWWP2chr16:69922152chr16:68936231ENST00000448661+8241_117304871.0DomainC2
HgeneWWP2chr16:69922152chr16:68936231ENST00000542271+5211_117188755.0DomainC2
HgeneWWP2chr16:69922152chr16:68936231ENST00000569174+891_117304336.0DomainC2
HgeneWWP2chr16:69922152chr16:68941346ENST00000356003+7231_117304871.0DomainC2
HgeneWWP2chr16:69922152chr16:68941346ENST00000359154+8241_117304871.0DomainC2
HgeneWWP2chr16:69922152chr16:68941346ENST00000448661+8241_117304871.0DomainC2
HgeneWWP2chr16:69922152chr16:68941346ENST00000542271+5211_117188755.0DomainC2
HgeneWWP2chr16:69922152chr16:68941346ENST00000569174+891_117304336.0DomainC2
TgeneTANGO6chr16:69820983chr16:69007931ENST000002617781318952_9889001095.0RepeatNote=HEAT 2
TgeneTANGO6chr16:69922152chr16:68936231ENST00000261778718873_9094961095.0RepeatNote=HEAT 1
TgeneTANGO6chr16:69922152chr16:68936231ENST00000261778718952_9884961095.0RepeatNote=HEAT 2
TgeneTANGO6chr16:69922152chr16:68941346ENST00000261778818873_9095551095.0RepeatNote=HEAT 1
TgeneTANGO6chr16:69922152chr16:68941346ENST00000261778818952_9885551095.0RepeatNote=HEAT 2

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneWWP2chr16:69820983chr16:69007931ENST00000356003+1231_11723871.0DomainC2
HgeneWWP2chr16:69820983chr16:69007931ENST00000356003+123300_33323871.0DomainWW 1
HgeneWWP2chr16:69820983chr16:69007931ENST00000356003+123330_36323871.0DomainWW 2
HgeneWWP2chr16:69820983chr16:69007931ENST00000356003+123405_43723871.0DomainWW 3
HgeneWWP2chr16:69820983chr16:69007931ENST00000356003+123444_47723871.0DomainWW 4
HgeneWWP2chr16:69820983chr16:69007931ENST00000356003+123536_87023871.0DomainHECT
HgeneWWP2chr16:69820983chr16:69007931ENST00000359154+2241_11723871.0DomainC2
HgeneWWP2chr16:69820983chr16:69007931ENST00000359154+224300_33323871.0DomainWW 1
HgeneWWP2chr16:69820983chr16:69007931ENST00000359154+224330_36323871.0DomainWW 2
HgeneWWP2chr16:69820983chr16:69007931ENST00000359154+224405_43723871.0DomainWW 3
HgeneWWP2chr16:69820983chr16:69007931ENST00000359154+224444_47723871.0DomainWW 4
HgeneWWP2chr16:69820983chr16:69007931ENST00000359154+224536_87023871.0DomainHECT
HgeneWWP2chr16:69820983chr16:69007931ENST00000448661+2241_11723871.0DomainC2
HgeneWWP2chr16:69820983chr16:69007931ENST00000448661+224300_33323871.0DomainWW 1
HgeneWWP2chr16:69820983chr16:69007931ENST00000448661+224330_36323871.0DomainWW 2
HgeneWWP2chr16:69820983chr16:69007931ENST00000448661+224405_43723871.0DomainWW 3
HgeneWWP2chr16:69820983chr16:69007931ENST00000448661+224444_47723871.0DomainWW 4
HgeneWWP2chr16:69820983chr16:69007931ENST00000448661+224536_87023871.0DomainHECT
HgeneWWP2chr16:69820983chr16:69007931ENST00000542271+1211_1170755.0DomainC2
HgeneWWP2chr16:69820983chr16:69007931ENST00000542271+121300_3330755.0DomainWW 1
HgeneWWP2chr16:69820983chr16:69007931ENST00000542271+121330_3630755.0DomainWW 2
HgeneWWP2chr16:69820983chr16:69007931ENST00000542271+121405_4370755.0DomainWW 3
HgeneWWP2chr16:69820983chr16:69007931ENST00000542271+121444_4770755.0DomainWW 4
HgeneWWP2chr16:69820983chr16:69007931ENST00000542271+121536_8700755.0DomainHECT
HgeneWWP2chr16:69820983chr16:69007931ENST00000568684+1141_1170432.0DomainC2
HgeneWWP2chr16:69820983chr16:69007931ENST00000568684+114300_3330432.0DomainWW 1
HgeneWWP2chr16:69820983chr16:69007931ENST00000568684+114330_3630432.0DomainWW 2
HgeneWWP2chr16:69820983chr16:69007931ENST00000568684+114405_4370432.0DomainWW 3
HgeneWWP2chr16:69820983chr16:69007931ENST00000568684+114444_4770432.0DomainWW 4
HgeneWWP2chr16:69820983chr16:69007931ENST00000568684+114536_8700432.0DomainHECT
HgeneWWP2chr16:69820983chr16:69007931ENST00000569174+291_11723336.0DomainC2
HgeneWWP2chr16:69820983chr16:69007931ENST00000569174+29300_33323336.0DomainWW 1
HgeneWWP2chr16:69820983chr16:69007931ENST00000569174+29330_36323336.0DomainWW 2
HgeneWWP2chr16:69820983chr16:69007931ENST00000569174+29405_43723336.0DomainWW 3
HgeneWWP2chr16:69820983chr16:69007931ENST00000569174+29444_47723336.0DomainWW 4
HgeneWWP2chr16:69820983chr16:69007931ENST00000569174+29536_87023336.0DomainHECT
HgeneWWP2chr16:69922152chr16:68936231ENST00000356003+723300_333304871.0DomainWW 1
HgeneWWP2chr16:69922152chr16:68936231ENST00000356003+723330_363304871.0DomainWW 2
HgeneWWP2chr16:69922152chr16:68936231ENST00000356003+723405_437304871.0DomainWW 3
HgeneWWP2chr16:69922152chr16:68936231ENST00000356003+723444_477304871.0DomainWW 4
HgeneWWP2chr16:69922152chr16:68936231ENST00000356003+723536_870304871.0DomainHECT
HgeneWWP2chr16:69922152chr16:68936231ENST00000359154+824300_333304871.0DomainWW 1
HgeneWWP2chr16:69922152chr16:68936231ENST00000359154+824330_363304871.0DomainWW 2
HgeneWWP2chr16:69922152chr16:68936231ENST00000359154+824405_437304871.0DomainWW 3
HgeneWWP2chr16:69922152chr16:68936231ENST00000359154+824444_477304871.0DomainWW 4
HgeneWWP2chr16:69922152chr16:68936231ENST00000359154+824536_870304871.0DomainHECT
HgeneWWP2chr16:69922152chr16:68936231ENST00000448661+824300_333304871.0DomainWW 1
HgeneWWP2chr16:69922152chr16:68936231ENST00000448661+824330_363304871.0DomainWW 2
HgeneWWP2chr16:69922152chr16:68936231ENST00000448661+824405_437304871.0DomainWW 3
HgeneWWP2chr16:69922152chr16:68936231ENST00000448661+824444_477304871.0DomainWW 4
HgeneWWP2chr16:69922152chr16:68936231ENST00000448661+824536_870304871.0DomainHECT
HgeneWWP2chr16:69922152chr16:68936231ENST00000542271+521300_333188755.0DomainWW 1
HgeneWWP2chr16:69922152chr16:68936231ENST00000542271+521330_363188755.0DomainWW 2
HgeneWWP2chr16:69922152chr16:68936231ENST00000542271+521405_437188755.0DomainWW 3
HgeneWWP2chr16:69922152chr16:68936231ENST00000542271+521444_477188755.0DomainWW 4
HgeneWWP2chr16:69922152chr16:68936231ENST00000542271+521536_870188755.0DomainHECT
HgeneWWP2chr16:69922152chr16:68936231ENST00000568684+1141_1170432.0DomainC2
HgeneWWP2chr16:69922152chr16:68936231ENST00000568684+114300_3330432.0DomainWW 1
HgeneWWP2chr16:69922152chr16:68936231ENST00000568684+114330_3630432.0DomainWW 2
HgeneWWP2chr16:69922152chr16:68936231ENST00000568684+114405_4370432.0DomainWW 3
HgeneWWP2chr16:69922152chr16:68936231ENST00000568684+114444_4770432.0DomainWW 4
HgeneWWP2chr16:69922152chr16:68936231ENST00000568684+114536_8700432.0DomainHECT
HgeneWWP2chr16:69922152chr16:68936231ENST00000569174+89300_333304336.0DomainWW 1
HgeneWWP2chr16:69922152chr16:68936231ENST00000569174+89330_363304336.0DomainWW 2
HgeneWWP2chr16:69922152chr16:68936231ENST00000569174+89405_437304336.0DomainWW 3
HgeneWWP2chr16:69922152chr16:68936231ENST00000569174+89444_477304336.0DomainWW 4
HgeneWWP2chr16:69922152chr16:68936231ENST00000569174+89536_870304336.0DomainHECT
HgeneWWP2chr16:69922152chr16:68941346ENST00000356003+723300_333304871.0DomainWW 1
HgeneWWP2chr16:69922152chr16:68941346ENST00000356003+723330_363304871.0DomainWW 2
HgeneWWP2chr16:69922152chr16:68941346ENST00000356003+723405_437304871.0DomainWW 3
HgeneWWP2chr16:69922152chr16:68941346ENST00000356003+723444_477304871.0DomainWW 4
HgeneWWP2chr16:69922152chr16:68941346ENST00000356003+723536_870304871.0DomainHECT
HgeneWWP2chr16:69922152chr16:68941346ENST00000359154+824300_333304871.0DomainWW 1
HgeneWWP2chr16:69922152chr16:68941346ENST00000359154+824330_363304871.0DomainWW 2
HgeneWWP2chr16:69922152chr16:68941346ENST00000359154+824405_437304871.0DomainWW 3
HgeneWWP2chr16:69922152chr16:68941346ENST00000359154+824444_477304871.0DomainWW 4
HgeneWWP2chr16:69922152chr16:68941346ENST00000359154+824536_870304871.0DomainHECT
HgeneWWP2chr16:69922152chr16:68941346ENST00000448661+824300_333304871.0DomainWW 1
HgeneWWP2chr16:69922152chr16:68941346ENST00000448661+824330_363304871.0DomainWW 2
HgeneWWP2chr16:69922152chr16:68941346ENST00000448661+824405_437304871.0DomainWW 3
HgeneWWP2chr16:69922152chr16:68941346ENST00000448661+824444_477304871.0DomainWW 4
HgeneWWP2chr16:69922152chr16:68941346ENST00000448661+824536_870304871.0DomainHECT
HgeneWWP2chr16:69922152chr16:68941346ENST00000542271+521300_333188755.0DomainWW 1
HgeneWWP2chr16:69922152chr16:68941346ENST00000542271+521330_363188755.0DomainWW 2
HgeneWWP2chr16:69922152chr16:68941346ENST00000542271+521405_437188755.0DomainWW 3
HgeneWWP2chr16:69922152chr16:68941346ENST00000542271+521444_477188755.0DomainWW 4
HgeneWWP2chr16:69922152chr16:68941346ENST00000542271+521536_870188755.0DomainHECT
HgeneWWP2chr16:69922152chr16:68941346ENST00000568684+1141_1170432.0DomainC2
HgeneWWP2chr16:69922152chr16:68941346ENST00000568684+114300_3330432.0DomainWW 1
HgeneWWP2chr16:69922152chr16:68941346ENST00000568684+114330_3630432.0DomainWW 2
HgeneWWP2chr16:69922152chr16:68941346ENST00000568684+114405_4370432.0DomainWW 3
HgeneWWP2chr16:69922152chr16:68941346ENST00000568684+114444_4770432.0DomainWW 4
HgeneWWP2chr16:69922152chr16:68941346ENST00000568684+114536_8700432.0DomainHECT
HgeneWWP2chr16:69922152chr16:68941346ENST00000569174+89300_333304336.0DomainWW 1
HgeneWWP2chr16:69922152chr16:68941346ENST00000569174+89330_363304336.0DomainWW 2
HgeneWWP2chr16:69922152chr16:68941346ENST00000569174+89405_437304336.0DomainWW 3
HgeneWWP2chr16:69922152chr16:68941346ENST00000569174+89444_477304336.0DomainWW 4
HgeneWWP2chr16:69922152chr16:68941346ENST00000569174+89536_870304336.0DomainHECT
TgeneTANGO6chr16:69820983chr16:69007931ENST000002617781318873_9099001095.0RepeatNote=HEAT 1
TgeneTANGO6chr16:69820983chr16:69007931ENST000002617781318468_4889001095.0TransmembraneHelical
TgeneTANGO6chr16:69922152chr16:68936231ENST00000261778718468_4884961095.0TransmembraneHelical
TgeneTANGO6chr16:69922152chr16:68941346ENST00000261778818468_4885551095.0TransmembraneHelical


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Fusion Gene Sequence for WWP2-TANGO6


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>99536_99536_1_WWP2-TANGO6_WWP2_chr16_69820983_ENST00000356003_TANGO6_chr16_69007931_ENST00000261778_length(transcript)=2199nt_BP=96nt
TTGTCTTACAGCTTCACGGTGATGATATGGCATCTGCCAGCTCTAGCCGGGCAGGAGTGGCCCTGCCTTTTGAGAAGTCTCAGCTCACTT
TGAAAGGGGTTGCCCTGCTGTCAGACGTCTATCCTGAGAAAATCTTGCCGGACTTGTTGGCTCAATATGACAGCAGCAAAGACAAGCACA
CACCAGAGACCAGAATGAAAGTCGGGGAAGTCCTTATGCGAATCGTCAGGGCATTAGGAGACATGGTCTCAAAGTACCGAGAACCTTTGA
TCCATACCTTCCTGAGGGGAGTGAGAGATCCTGATGGTGCTCACAGGGCCAGCAGCTTGGCCAACCTTGGGGAGCTGTGCCAGAGGCTGG
ACTTTCTGCTGGGCTCCGTGGTCCATGAGGTAACAGCTTGCCTGATTGCTGTGGCCAAAACAGATGGTGAAGTTCAAGTACGCAGAGCTG
CCATACATGTGGTTGTGCTGCTGCTTCGGGGACTCAGCCAGAAAGCTACTGAGGTGCTGAGCGCCGTCCTCAAGGATCTCTACCACCTGC
TGAAGCACGTAGTGTGTCTGGAGCCCGATGACGTGGCCAAGCTCCATGCCCAGTTGGCCCTAGAAGAGCTGGATGACATCATGAAAAACT
TCCTGTTCCCTCCACAGAAGCTGGAGAAGAAGATCATGGTCCTGCCGTAGACCTGGCTCCAAGGACGTGGAGGAGGCAGGCAGGGCCAGG
CACCCAGAGCCGTGCCCAGGTCTTCCAGCAGGTGGCCCTGCTGCCTCTTGAGTGCTGGCAGCATGGCTGACCCTCGGGGTGGTTTTATGG
TGCAGGTCACTTGGGTCTTCAGGGTCCCTTCCGAGGGCATGTGTTCAGCACTCCCGCGTTCAGCCTGAGGGGTGTACAGTTAAGAGAAGA
CAGTTACAGATCTCATTAATCTACATTTTTCACTGTCCTCTAGCATTGAAAGAAGGATGTCTACCTGGTGAAAGTATATTTTAACATGAC
TGATGGAATTTCACTAATTGCCCACTCTCTTGGAACTTGAGGAGAAGCGGTTGGCCACCCATATGTCACCTAGCTCTATATTCTTTCAGG
CTGAGATTCTTCTTCAGGAAAATGAGGAGCAGAACTGGCCACCCTTGGCTGCTCAAGAGGCATTTCAGAGTAGGAGATGCAGTTGGAGGT
GGGGAGGGGAAGGAAATAGTTATCAAATAATGCAAAATGGAATAAAGTTATCTTGGATGGAAAGAACAGGGCTAAATCTGGTCCTCTGGT
GTCGAGATGGAAAACTGTGGAGTTGAAGAGGCTCTGATGCCCAGAAAGGACAATCAAGCTGGTTGACTCTTCCAGAGAAGAAGGGTAAGC
CCTGTATTTATCCTCCCAGGCCATTCTTCTTCACTCCTGCTGCTGTTTGCAGAGAGTTGCCCTGATTATCAGGAGAAAAGAACCACGAGC
ATCCAGAGAGTTTACATCCTGCCTTCTGTCCTCTGCTCCTTCAGAAAGATGAATGCCTAGACAATGGGTTCACACTGAATGCAGGCTGGA
AAGAATGCATGCTGGTGGCCTAATGCCAGGGCTGTTGAAACAATTTCAGATATAGCACTGTGGTCTCCACTTTATTTCTTTATATGTTTT
GGCCGCTGCATTTTGATTGCAGCTAAAAGAGATAACAGAAAGGAGATACTGGCTGGCTGCTTCATATTAGCCCTCTCTGTTGTCAACACC
TTGATGAGGCCAACCCAGAGATGCTTGATCAGTCCTCAGCTTTGCAGGGCTAGGTACAGAATTTTATCACAGGATTTTATCACGCTCTCT
GGGGTGACTAGATCCACAGGAACCAAAACGCAGTTTCCAAAAGCTCGAGTGACTGAAGGATCTATACACAAACATGGCTATTTGCTAGTT
AACAACAGGATATTTCTCTCTGGCCAGATCACAGACATGGTTCTGAGTCAGATCTTCCTTGGTGGCATCCCTTTAAAGAGGCCATCTTAT
GAACAGGATCACAAGTGAGCTTAGTGAGCAGAGAGTTAGAACAAATCTAGCTAGGTGTGTTTAAGGAATATTTCCATTCAGCTAGTGTAG
CTGGATTAATTTCTATTCTCCAAATCAAGGATGTCTAGAAAATGGGCATTGTGGCTTTCAAATCTAAGAAGAATCTCCTTTGGGCCAGCT

>99536_99536_1_WWP2-TANGO6_WWP2_chr16_69820983_ENST00000356003_TANGO6_chr16_69007931_ENST00000261778_length(amino acids)=217AA_BP=23
MASASSSRAGVALPFEKSQLTLKGVALLSDVYPEKILPDLLAQYDSSKDKHTPETRMKVGEVLMRIVRALGDMVSKYREPLIHTFLRGVR
DPDGAHRASSLANLGELCQRLDFLLGSVVHEVTACLIAVAKTDGEVQVRRAAIHVVVLLLRGLSQKATEVLSAVLKDLYHLLKHVVCLEP

--------------------------------------------------------------
>99536_99536_2_WWP2-TANGO6_WWP2_chr16_69820983_ENST00000359154_TANGO6_chr16_69007931_ENST00000261778_length(transcript)=2274nt_BP=171nt
GCGCGGTCACGTGACCCGGCCCGAGTGCGGGCGGTGGAAGGCGGAAGTAGGAGAGGAGTTCGGCGCCGCTTCTGTGGCCACGGCAGCTTC
ACGGTGATGATATGGCATCTGCCAGCTCTAGCCGGGCAGGAGTGGCCCTGCCTTTTGAGAAGTCTCAGCTCACTTTGAAAGGGGTTGCCC
TGCTGTCAGACGTCTATCCTGAGAAAATCTTGCCGGACTTGTTGGCTCAATATGACAGCAGCAAAGACAAGCACACACCAGAGACCAGAA
TGAAAGTCGGGGAAGTCCTTATGCGAATCGTCAGGGCATTAGGAGACATGGTCTCAAAGTACCGAGAACCTTTGATCCATACCTTCCTGA
GGGGAGTGAGAGATCCTGATGGTGCTCACAGGGCCAGCAGCTTGGCCAACCTTGGGGAGCTGTGCCAGAGGCTGGACTTTCTGCTGGGCT
CCGTGGTCCATGAGGTAACAGCTTGCCTGATTGCTGTGGCCAAAACAGATGGTGAAGTTCAAGTACGCAGAGCTGCCATACATGTGGTTG
TGCTGCTGCTTCGGGGACTCAGCCAGAAAGCTACTGAGGTGCTGAGCGCCGTCCTCAAGGATCTCTACCACCTGCTGAAGCACGTAGTGT
GTCTGGAGCCCGATGACGTGGCCAAGCTCCATGCCCAGTTGGCCCTAGAAGAGCTGGATGACATCATGAAAAACTTCCTGTTCCCTCCAC
AGAAGCTGGAGAAGAAGATCATGGTCCTGCCGTAGACCTGGCTCCAAGGACGTGGAGGAGGCAGGCAGGGCCAGGCACCCAGAGCCGTGC
CCAGGTCTTCCAGCAGGTGGCCCTGCTGCCTCTTGAGTGCTGGCAGCATGGCTGACCCTCGGGGTGGTTTTATGGTGCAGGTCACTTGGG
TCTTCAGGGTCCCTTCCGAGGGCATGTGTTCAGCACTCCCGCGTTCAGCCTGAGGGGTGTACAGTTAAGAGAAGACAGTTACAGATCTCA
TTAATCTACATTTTTCACTGTCCTCTAGCATTGAAAGAAGGATGTCTACCTGGTGAAAGTATATTTTAACATGACTGATGGAATTTCACT
AATTGCCCACTCTCTTGGAACTTGAGGAGAAGCGGTTGGCCACCCATATGTCACCTAGCTCTATATTCTTTCAGGCTGAGATTCTTCTTC
AGGAAAATGAGGAGCAGAACTGGCCACCCTTGGCTGCTCAAGAGGCATTTCAGAGTAGGAGATGCAGTTGGAGGTGGGGAGGGGAAGGAA
ATAGTTATCAAATAATGCAAAATGGAATAAAGTTATCTTGGATGGAAAGAACAGGGCTAAATCTGGTCCTCTGGTGTCGAGATGGAAAAC
TGTGGAGTTGAAGAGGCTCTGATGCCCAGAAAGGACAATCAAGCTGGTTGACTCTTCCAGAGAAGAAGGGTAAGCCCTGTATTTATCCTC
CCAGGCCATTCTTCTTCACTCCTGCTGCTGTTTGCAGAGAGTTGCCCTGATTATCAGGAGAAAAGAACCACGAGCATCCAGAGAGTTTAC
ATCCTGCCTTCTGTCCTCTGCTCCTTCAGAAAGATGAATGCCTAGACAATGGGTTCACACTGAATGCAGGCTGGAAAGAATGCATGCTGG
TGGCCTAATGCCAGGGCTGTTGAAACAATTTCAGATATAGCACTGTGGTCTCCACTTTATTTCTTTATATGTTTTGGCCGCTGCATTTTG
ATTGCAGCTAAAAGAGATAACAGAAAGGAGATACTGGCTGGCTGCTTCATATTAGCCCTCTCTGTTGTCAACACCTTGATGAGGCCAACC
CAGAGATGCTTGATCAGTCCTCAGCTTTGCAGGGCTAGGTACAGAATTTTATCACAGGATTTTATCACGCTCTCTGGGGTGACTAGATCC
ACAGGAACCAAAACGCAGTTTCCAAAAGCTCGAGTGACTGAAGGATCTATACACAAACATGGCTATTTGCTAGTTAACAACAGGATATTT
CTCTCTGGCCAGATCACAGACATGGTTCTGAGTCAGATCTTCCTTGGTGGCATCCCTTTAAAGAGGCCATCTTATGAACAGGATCACAAG
TGAGCTTAGTGAGCAGAGAGTTAGAACAAATCTAGCTAGGTGTGTTTAAGGAATATTTCCATTCAGCTAGTGTAGCTGGATTAATTTCTA
TTCTCCAAATCAAGGATGTCTAGAAAATGGGCATTGTGGCTTTCAAATCTAAGAAGAATCTCCTTTGGGCCAGCTGGATGTACAATAAAA

>99536_99536_2_WWP2-TANGO6_WWP2_chr16_69820983_ENST00000359154_TANGO6_chr16_69007931_ENST00000261778_length(amino acids)=227AA_BP=33
MWPRQLHGDDMASASSSRAGVALPFEKSQLTLKGVALLSDVYPEKILPDLLAQYDSSKDKHTPETRMKVGEVLMRIVRALGDMVSKYREP
LIHTFLRGVRDPDGAHRASSLANLGELCQRLDFLLGSVVHEVTACLIAVAKTDGEVQVRRAAIHVVVLLLRGLSQKATEVLSAVLKDLYH

--------------------------------------------------------------
>99536_99536_3_WWP2-TANGO6_WWP2_chr16_69820983_ENST00000448661_TANGO6_chr16_69007931_ENST00000261778_length(transcript)=2251nt_BP=148nt
TTCGGCGCCGCTTCTGTGGCCACGGCAGGTAGCGAGCGCTGGCGCGGGGGGCGCGTCTTACAGCTTCACGGTGATGATATGGCATCTGCC
AGCTCTAGCCGGGCAGGAGTGGCCCTGCCTTTTGAGAAGTCTCAGCTCACTTTGAAAGGGGTTGCCCTGCTGTCAGACGTCTATCCTGAG
AAAATCTTGCCGGACTTGTTGGCTCAATATGACAGCAGCAAAGACAAGCACACACCAGAGACCAGAATGAAAGTCGGGGAAGTCCTTATG
CGAATCGTCAGGGCATTAGGAGACATGGTCTCAAAGTACCGAGAACCTTTGATCCATACCTTCCTGAGGGGAGTGAGAGATCCTGATGGT
GCTCACAGGGCCAGCAGCTTGGCCAACCTTGGGGAGCTGTGCCAGAGGCTGGACTTTCTGCTGGGCTCCGTGGTCCATGAGGTAACAGCT
TGCCTGATTGCTGTGGCCAAAACAGATGGTGAAGTTCAAGTACGCAGAGCTGCCATACATGTGGTTGTGCTGCTGCTTCGGGGACTCAGC
CAGAAAGCTACTGAGGTGCTGAGCGCCGTCCTCAAGGATCTCTACCACCTGCTGAAGCACGTAGTGTGTCTGGAGCCCGATGACGTGGCC
AAGCTCCATGCCCAGTTGGCCCTAGAAGAGCTGGATGACATCATGAAAAACTTCCTGTTCCCTCCACAGAAGCTGGAGAAGAAGATCATG
GTCCTGCCGTAGACCTGGCTCCAAGGACGTGGAGGAGGCAGGCAGGGCCAGGCACCCAGAGCCGTGCCCAGGTCTTCCAGCAGGTGGCCC
TGCTGCCTCTTGAGTGCTGGCAGCATGGCTGACCCTCGGGGTGGTTTTATGGTGCAGGTCACTTGGGTCTTCAGGGTCCCTTCCGAGGGC
ATGTGTTCAGCACTCCCGCGTTCAGCCTGAGGGGTGTACAGTTAAGAGAAGACAGTTACAGATCTCATTAATCTACATTTTTCACTGTCC
TCTAGCATTGAAAGAAGGATGTCTACCTGGTGAAAGTATATTTTAACATGACTGATGGAATTTCACTAATTGCCCACTCTCTTGGAACTT
GAGGAGAAGCGGTTGGCCACCCATATGTCACCTAGCTCTATATTCTTTCAGGCTGAGATTCTTCTTCAGGAAAATGAGGAGCAGAACTGG
CCACCCTTGGCTGCTCAAGAGGCATTTCAGAGTAGGAGATGCAGTTGGAGGTGGGGAGGGGAAGGAAATAGTTATCAAATAATGCAAAAT
GGAATAAAGTTATCTTGGATGGAAAGAACAGGGCTAAATCTGGTCCTCTGGTGTCGAGATGGAAAACTGTGGAGTTGAAGAGGCTCTGAT
GCCCAGAAAGGACAATCAAGCTGGTTGACTCTTCCAGAGAAGAAGGGTAAGCCCTGTATTTATCCTCCCAGGCCATTCTTCTTCACTCCT
GCTGCTGTTTGCAGAGAGTTGCCCTGATTATCAGGAGAAAAGAACCACGAGCATCCAGAGAGTTTACATCCTGCCTTCTGTCCTCTGCTC
CTTCAGAAAGATGAATGCCTAGACAATGGGTTCACACTGAATGCAGGCTGGAAAGAATGCATGCTGGTGGCCTAATGCCAGGGCTGTTGA
AACAATTTCAGATATAGCACTGTGGTCTCCACTTTATTTCTTTATATGTTTTGGCCGCTGCATTTTGATTGCAGCTAAAAGAGATAACAG
AAAGGAGATACTGGCTGGCTGCTTCATATTAGCCCTCTCTGTTGTCAACACCTTGATGAGGCCAACCCAGAGATGCTTGATCAGTCCTCA
GCTTTGCAGGGCTAGGTACAGAATTTTATCACAGGATTTTATCACGCTCTCTGGGGTGACTAGATCCACAGGAACCAAAACGCAGTTTCC
AAAAGCTCGAGTGACTGAAGGATCTATACACAAACATGGCTATTTGCTAGTTAACAACAGGATATTTCTCTCTGGCCAGATCACAGACAT
GGTTCTGAGTCAGATCTTCCTTGGTGGCATCCCTTTAAAGAGGCCATCTTATGAACAGGATCACAAGTGAGCTTAGTGAGCAGAGAGTTA
GAACAAATCTAGCTAGGTGTGTTTAAGGAATATTTCCATTCAGCTAGTGTAGCTGGATTAATTTCTATTCTCCAAATCAAGGATGTCTAG
AAAATGGGCATTGTGGCTTTCAAATCTAAGAAGAATCTCCTTTGGGCCAGCTGGATGTACAATAAAAATGCTTGTTTCTTGGCCTTCCTT

>99536_99536_3_WWP2-TANGO6_WWP2_chr16_69820983_ENST00000448661_TANGO6_chr16_69007931_ENST00000261778_length(amino acids)=217AA_BP=23
MASASSSRAGVALPFEKSQLTLKGVALLSDVYPEKILPDLLAQYDSSKDKHTPETRMKVGEVLMRIVRALGDMVSKYREPLIHTFLRGVR
DPDGAHRASSLANLGELCQRLDFLLGSVVHEVTACLIAVAKTDGEVQVRRAAIHVVVLLLRGLSQKATEVLSAVLKDLYHLLKHVVCLEP

--------------------------------------------------------------
>99536_99536_4_WWP2-TANGO6_WWP2_chr16_69820983_ENST00000569174_TANGO6_chr16_69007931_ENST00000261778_length(transcript)=2243nt_BP=140nt
AGATGAAACAGAAAGGCTAAAGAGGGCTGGAGTCAGGGGACTTCTCTTCCACCAGCTTCACGGTGATGATATGGCATCTGCCAGCTCTAG
CCGGGCAGGAGTGGCCCTGCCTTTTGAGAAGTCTCAGCTCACTTTGAAAGGGGTTGCCCTGCTGTCAGACGTCTATCCTGAGAAAATCTT
GCCGGACTTGTTGGCTCAATATGACAGCAGCAAAGACAAGCACACACCAGAGACCAGAATGAAAGTCGGGGAAGTCCTTATGCGAATCGT
CAGGGCATTAGGAGACATGGTCTCAAAGTACCGAGAACCTTTGATCCATACCTTCCTGAGGGGAGTGAGAGATCCTGATGGTGCTCACAG
GGCCAGCAGCTTGGCCAACCTTGGGGAGCTGTGCCAGAGGCTGGACTTTCTGCTGGGCTCCGTGGTCCATGAGGTAACAGCTTGCCTGAT
TGCTGTGGCCAAAACAGATGGTGAAGTTCAAGTACGCAGAGCTGCCATACATGTGGTTGTGCTGCTGCTTCGGGGACTCAGCCAGAAAGC
TACTGAGGTGCTGAGCGCCGTCCTCAAGGATCTCTACCACCTGCTGAAGCACGTAGTGTGTCTGGAGCCCGATGACGTGGCCAAGCTCCA
TGCCCAGTTGGCCCTAGAAGAGCTGGATGACATCATGAAAAACTTCCTGTTCCCTCCACAGAAGCTGGAGAAGAAGATCATGGTCCTGCC
GTAGACCTGGCTCCAAGGACGTGGAGGAGGCAGGCAGGGCCAGGCACCCAGAGCCGTGCCCAGGTCTTCCAGCAGGTGGCCCTGCTGCCT
CTTGAGTGCTGGCAGCATGGCTGACCCTCGGGGTGGTTTTATGGTGCAGGTCACTTGGGTCTTCAGGGTCCCTTCCGAGGGCATGTGTTC
AGCACTCCCGCGTTCAGCCTGAGGGGTGTACAGTTAAGAGAAGACAGTTACAGATCTCATTAATCTACATTTTTCACTGTCCTCTAGCAT
TGAAAGAAGGATGTCTACCTGGTGAAAGTATATTTTAACATGACTGATGGAATTTCACTAATTGCCCACTCTCTTGGAACTTGAGGAGAA
GCGGTTGGCCACCCATATGTCACCTAGCTCTATATTCTTTCAGGCTGAGATTCTTCTTCAGGAAAATGAGGAGCAGAACTGGCCACCCTT
GGCTGCTCAAGAGGCATTTCAGAGTAGGAGATGCAGTTGGAGGTGGGGAGGGGAAGGAAATAGTTATCAAATAATGCAAAATGGAATAAA
GTTATCTTGGATGGAAAGAACAGGGCTAAATCTGGTCCTCTGGTGTCGAGATGGAAAACTGTGGAGTTGAAGAGGCTCTGATGCCCAGAA
AGGACAATCAAGCTGGTTGACTCTTCCAGAGAAGAAGGGTAAGCCCTGTATTTATCCTCCCAGGCCATTCTTCTTCACTCCTGCTGCTGT
TTGCAGAGAGTTGCCCTGATTATCAGGAGAAAAGAACCACGAGCATCCAGAGAGTTTACATCCTGCCTTCTGTCCTCTGCTCCTTCAGAA
AGATGAATGCCTAGACAATGGGTTCACACTGAATGCAGGCTGGAAAGAATGCATGCTGGTGGCCTAATGCCAGGGCTGTTGAAACAATTT
CAGATATAGCACTGTGGTCTCCACTTTATTTCTTTATATGTTTTGGCCGCTGCATTTTGATTGCAGCTAAAAGAGATAACAGAAAGGAGA
TACTGGCTGGCTGCTTCATATTAGCCCTCTCTGTTGTCAACACCTTGATGAGGCCAACCCAGAGATGCTTGATCAGTCCTCAGCTTTGCA
GGGCTAGGTACAGAATTTTATCACAGGATTTTATCACGCTCTCTGGGGTGACTAGATCCACAGGAACCAAAACGCAGTTTCCAAAAGCTC
GAGTGACTGAAGGATCTATACACAAACATGGCTATTTGCTAGTTAACAACAGGATATTTCTCTCTGGCCAGATCACAGACATGGTTCTGA
GTCAGATCTTCCTTGGTGGCATCCCTTTAAAGAGGCCATCTTATGAACAGGATCACAAGTGAGCTTAGTGAGCAGAGAGTTAGAACAAAT
CTAGCTAGGTGTGTTTAAGGAATATTTCCATTCAGCTAGTGTAGCTGGATTAATTTCTATTCTCCAAATCAAGGATGTCTAGAAAATGGG

>99536_99536_4_WWP2-TANGO6_WWP2_chr16_69820983_ENST00000569174_TANGO6_chr16_69007931_ENST00000261778_length(amino acids)=217AA_BP=23
MASASSSRAGVALPFEKSQLTLKGVALLSDVYPEKILPDLLAQYDSSKDKHTPETRMKVGEVLMRIVRALGDMVSKYREPLIHTFLRGVR
DPDGAHRASSLANLGELCQRLDFLLGSVVHEVTACLIAVAKTDGEVQVRRAAIHVVVLLLRGLSQKATEVLSAVLKDLYHLLKHVVCLEP

--------------------------------------------------------------
>99536_99536_5_WWP2-TANGO6_WWP2_chr16_69922152_ENST00000356003_TANGO6_chr16_68936231_ENST00000261778_length(transcript)=4254nt_BP=940nt
TTGTCTTACAGCTTCACGGTGATGATATGGCATCTGCCAGCTCTAGCCGGGCAGGAGTGGCCCTGCCTTTTGAGAAGTCTCAGCTCACTT
TGAAAGTGGTGTCCGCAAAGCCCAAGGTGCATAATCGTCAACCTCGAATTAACTCCTACGTGGAGGTGGCGGTGGATGGACTCCCCAGTG
AGACCAAGAAGACTGGGAAGCGCATTGGGAGCTCTGAGCTTCTCTGGAATGAGATCATCATTTTGAATGTCACGGCACAGAGTCATTTAG
ATTTAAAGGTCTGGAGCTGCCATACCTTGAGAAATGAACTGCTAGGCACCGCATCTGTCAACCTCTCCAACGTCTTGAAGAACAATGGGG
GCAAAATGGAGAACATGCAGCTGACCCTGAACCTGCAGACGGAGAACAAAGGCAGCGTTGTCTCAGGCGGAGAGCTGACAATTTTCCTGG
ACGGGCCAACTGTTGATCTGGGAAATGTGCCTAATGGCAGTGCCCTGACAGATGGATCACAGCTGCCTTCGAGAGACTCCAGTGGAACAG
CAGTAGCTCCAGAGAACCGGCACCAGCCCCCCAGCACAAACTGCTTTGGTGGAAGATCCCGGACGCACAGACATTCGGGTGCTTCAGCCA
GAACAACCCCAGCAACCGGCGAGCAAAGCCCCGGTGCTCGGAGCCGGCACCGCCAGCCCGTCAAGAACTCAGGCCACAGTGGCTTGGCCA
ATGGCACAGTGAATGATGAACCCACAACAGCCACTGATCCCGAAGAACCTTCCGTTGTTGGTGTGACGTCCCCACCTGCTGCACCCTTGA
GTGTGACCCCGAATCCCAACACGACTTCTCTCCCTGCCCCAGCCACACCGGCTGAAGGAGAGGAACCCAGCACTTCGGGTACACAGCAGC
TCCCAGCGGCTGCCCAGGCCCCCGACGCTCTGCCTGCTGGGTCACTTTGCCAAGAAATCTTATTATGGATTCTGGGGAAGCTGGAAAGGA
AGAAGGCAATTGCCAGCCTGAAAGGATTTGCAGGGTTGGACAAAGCTGTGCCCTCTCTCCATTCTCTGTGTCAGTTTAGAGTTGCCACTC
AAGGTGGCATTATGATTACCATCAAAGAGGCCATTAGTGATGAAGATGAAGATGAAGCCCTGTACCAGAAGGTATCCTCTGAGCAGGGCC
GGGTGGAGCATCTCGGGGACTTGCTGTCCCACTGCCAGGAATGCGGTTTGGCAGGAGACTTCTTCATCTTCTGTTTGAAAGAGTTGACTC
ATGTGGCCTCGGAAAATGAAACAGAGTTAAAAACTGAGCCCTTCTCCAGCAAGAGCCTCTTGGAATTAGAGCAACATCAGACTCTTCTTG
TGGAAGGCCAAGAGCGGAAGCTGCTTGTCCTGCAGCTGATGGCTGTTCTGTGCGAGAGAATGTCTGAGCAGATATTCACAAACGTCACTC
AGGTGGTGGACTTTGTAGCAGCAACATTGCAGAGAGCCTGTGCAAGCCTGGCCCATCAGGCAGAGAGCACCGTGGAATCACAGACGCTGA
GCATGTCCATGGGGCTGGTGGCTGTCATGCTAGGAGGAGCTGTTCAGTTGAAGTCAAGTGATTTTGCTGTTCTGAAGCAGTTGTTGCCTC
TGTTGGAGAAGGTATCCAACACATACCCTGATCCGGTCATCCAAGAACTCGCTGTTGATCTCCGCATCACCATCTCTACCCATGGAGCCT
TTGCCACTGAGGCCGTCAGCATGGCTGCCCAAAGTACACTGAACAGAAAAGATCTGGAAGGGAAAATAGAAGAGCAGCAACAAACCAGTC
ATGAAAGACCCACTGATGTAGCTCATAGCCACCTTGAACAACAGCAGAGCCATGAGACAGCCCCCCAGACAGGCCTGCAGTCAAATGCTC
CAATCATTCCTCAAGGAGTCAATGAGCCCAGCACTACTACAAGTCAGAAATCTGGAAGCGTAACCACAGAACAGCTCCAAGAGGTTCTTT
TGTCAGCTTATGACCCTCAAATTCCAACACGGGCTGCTGCCCTGCGTACTCTTTCCCACTGGATAGAGCAGAGAGAAGCAAAAGCCCTTG
AGATGCAAGAGAAGCTTCTCAAGATATTCTTGGAAAACTTGGAACATGAAGACACTTTTGTATATCTATCTGCAATTCAGGGGGTTGCCC
TGCTGTCAGACGTCTATCCTGAGAAAATCTTGCCGGACTTGTTGGCTCAATATGACAGCAGCAAAGACAAGCACACACCAGAGACCAGAA
TGAAAGTCGGGGAAGTCCTTATGCGAATCGTCAGGGCATTAGGAGACATGGTCTCAAAGTACCGAGAACCTTTGATCCATACCTTCCTGA
GGGGAGTGAGAGATCCTGATGGTGCTCACAGGGCCAGCAGCTTGGCCAACCTTGGGGAGCTGTGCCAGAGGCTGGACTTTCTGCTGGGCT
CCGTGGTCCATGAGGTAACAGCTTGCCTGATTGCTGTGGCCAAAACAGATGGTGAAGTTCAAGTACGCAGAGCTGCCATACATGTGGTTG
TGCTGCTGCTTCGGGGACTCAGCCAGAAAGCTACTGAGGTGCTGAGCGCCGTCCTCAAGGATCTCTACCACCTGCTGAAGCACGTAGTGT
GTCTGGAGCCCGATGACGTGGCCAAGCTCCATGCCCAGTTGGCCCTAGAAGAGCTGGATGACATCATGAAAAACTTCCTGTTCCCTCCAC
AGAAGCTGGAGAAGAAGATCATGGTCCTGCCGTAGACCTGGCTCCAAGGACGTGGAGGAGGCAGGCAGGGCCAGGCACCCAGAGCCGTGC
CCAGGTCTTCCAGCAGGTGGCCCTGCTGCCTCTTGAGTGCTGGCAGCATGGCTGACCCTCGGGGTGGTTTTATGGTGCAGGTCACTTGGG
TCTTCAGGGTCCCTTCCGAGGGCATGTGTTCAGCACTCCCGCGTTCAGCCTGAGGGGTGTACAGTTAAGAGAAGACAGTTACAGATCTCA
TTAATCTACATTTTTCACTGTCCTCTAGCATTGAAAGAAGGATGTCTACCTGGTGAAAGTATATTTTAACATGACTGATGGAATTTCACT
AATTGCCCACTCTCTTGGAACTTGAGGAGAAGCGGTTGGCCACCCATATGTCACCTAGCTCTATATTCTTTCAGGCTGAGATTCTTCTTC
AGGAAAATGAGGAGCAGAACTGGCCACCCTTGGCTGCTCAAGAGGCATTTCAGAGTAGGAGATGCAGTTGGAGGTGGGGAGGGGAAGGAA
ATAGTTATCAAATAATGCAAAATGGAATAAAGTTATCTTGGATGGAAAGAACAGGGCTAAATCTGGTCCTCTGGTGTCGAGATGGAAAAC
TGTGGAGTTGAAGAGGCTCTGATGCCCAGAAAGGACAATCAAGCTGGTTGACTCTTCCAGAGAAGAAGGGTAAGCCCTGTATTTATCCTC
CCAGGCCATTCTTCTTCACTCCTGCTGCTGTTTGCAGAGAGTTGCCCTGATTATCAGGAGAAAAGAACCACGAGCATCCAGAGAGTTTAC
ATCCTGCCTTCTGTCCTCTGCTCCTTCAGAAAGATGAATGCCTAGACAATGGGTTCACACTGAATGCAGGCTGGAAAGAATGCATGCTGG
TGGCCTAATGCCAGGGCTGTTGAAACAATTTCAGATATAGCACTGTGGTCTCCACTTTATTTCTTTATATGTTTTGGCCGCTGCATTTTG
ATTGCAGCTAAAAGAGATAACAGAAAGGAGATACTGGCTGGCTGCTTCATATTAGCCCTCTCTGTTGTCAACACCTTGATGAGGCCAACC
CAGAGATGCTTGATCAGTCCTCAGCTTTGCAGGGCTAGGTACAGAATTTTATCACAGGATTTTATCACGCTCTCTGGGGTGACTAGATCC
ACAGGAACCAAAACGCAGTTTCCAAAAGCTCGAGTGACTGAAGGATCTATACACAAACATGGCTATTTGCTAGTTAACAACAGGATATTT
CTCTCTGGCCAGATCACAGACATGGTTCTGAGTCAGATCTTCCTTGGTGGCATCCCTTTAAAGAGGCCATCTTATGAACAGGATCACAAG
TGAGCTTAGTGAGCAGAGAGTTAGAACAAATCTAGCTAGGTGTGTTTAAGGAATATTTCCATTCAGCTAGTGTAGCTGGATTAATTTCTA
TTCTCCAAATCAAGGATGTCTAGAAAATGGGCATTGTGGCTTTCAAATCTAAGAAGAATCTCCTTTGGGCCAGCTGGATGTACAATAAAA

>99536_99536_5_WWP2-TANGO6_WWP2_chr16_69922152_ENST00000356003_TANGO6_chr16_68936231_ENST00000261778_length(amino acids)=902AA_BP=303
MASASSSRAGVALPFEKSQLTLKVVSAKPKVHNRQPRINSYVEVAVDGLPSETKKTGKRIGSSELLWNEIIILNVTAQSHLDLKVWSCHT
LRNELLGTASVNLSNVLKNNGGKMENMQLTLNLQTENKGSVVSGGELTIFLDGPTVDLGNVPNGSALTDGSQLPSRDSSGTAVAPENRHQ
PPSTNCFGGRSRTHRHSGASARTTPATGEQSPGARSRHRQPVKNSGHSGLANGTVNDEPTTATDPEEPSVVGVTSPPAAPLSVTPNPNTT
SLPAPATPAEGEEPSTSGTQQLPAAAQAPDALPAGSLCQEILLWILGKLERKKAIASLKGFAGLDKAVPSLHSLCQFRVATQGGIMITIK
EAISDEDEDEALYQKVSSEQGRVEHLGDLLSHCQECGLAGDFFIFCLKELTHVASENETELKTEPFSSKSLLELEQHQTLLVEGQERKLL
VLQLMAVLCERMSEQIFTNVTQVVDFVAATLQRACASLAHQAESTVESQTLSMSMGLVAVMLGGAVQLKSSDFAVLKQLLPLLEKVSNTY
PDPVIQELAVDLRITISTHGAFATEAVSMAAQSTLNRKDLEGKIEEQQQTSHERPTDVAHSHLEQQQSHETAPQTGLQSNAPIIPQGVNE
PSTTTSQKSGSVTTEQLQEVLLSAYDPQIPTRAAALRTLSHWIEQREAKALEMQEKLLKIFLENLEHEDTFVYLSAIQGVALLSDVYPEK
ILPDLLAQYDSSKDKHTPETRMKVGEVLMRIVRALGDMVSKYREPLIHTFLRGVRDPDGAHRASSLANLGELCQRLDFLLGSVVHEVTAC
LIAVAKTDGEVQVRRAAIHVVVLLLRGLSQKATEVLSAVLKDLYHLLKHVVCLEPDDVAKLHAQLALEELDDIMKNFLFPPQKLEKKIMV

--------------------------------------------------------------
>99536_99536_6_WWP2-TANGO6_WWP2_chr16_69922152_ENST00000356003_TANGO6_chr16_68941346_ENST00000261778_length(transcript)=4077nt_BP=940nt
TTGTCTTACAGCTTCACGGTGATGATATGGCATCTGCCAGCTCTAGCCGGGCAGGAGTGGCCCTGCCTTTTGAGAAGTCTCAGCTCACTT
TGAAAGTGGTGTCCGCAAAGCCCAAGGTGCATAATCGTCAACCTCGAATTAACTCCTACGTGGAGGTGGCGGTGGATGGACTCCCCAGTG
AGACCAAGAAGACTGGGAAGCGCATTGGGAGCTCTGAGCTTCTCTGGAATGAGATCATCATTTTGAATGTCACGGCACAGAGTCATTTAG
ATTTAAAGGTCTGGAGCTGCCATACCTTGAGAAATGAACTGCTAGGCACCGCATCTGTCAACCTCTCCAACGTCTTGAAGAACAATGGGG
GCAAAATGGAGAACATGCAGCTGACCCTGAACCTGCAGACGGAGAACAAAGGCAGCGTTGTCTCAGGCGGAGAGCTGACAATTTTCCTGG
ACGGGCCAACTGTTGATCTGGGAAATGTGCCTAATGGCAGTGCCCTGACAGATGGATCACAGCTGCCTTCGAGAGACTCCAGTGGAACAG
CAGTAGCTCCAGAGAACCGGCACCAGCCCCCCAGCACAAACTGCTTTGGTGGAAGATCCCGGACGCACAGACATTCGGGTGCTTCAGCCA
GAACAACCCCAGCAACCGGCGAGCAAAGCCCCGGTGCTCGGAGCCGGCACCGCCAGCCCGTCAAGAACTCAGGCCACAGTGGCTTGGCCA
ATGGCACAGTGAATGATGAACCCACAACAGCCACTGATCCCGAAGAACCTTCCGTTGTTGGTGTGACGTCCCCACCTGCTGCACCCTTGA
GTGTGACCCCGAATCCCAACACGACTTCTCTCCCTGCCCCAGCCACACCGGCTGAAGGAGAGGAACCCAGCACTTCGGGTACACAGCAGC
TCCCAGCGGCTGCCCAGGCCCCCGACGCTCTGCCTGCTGGTGATGAAGATGAAGATGAAGCCCTGTACCAGAAGGTATCCTCTGAGCAGG
GCCGGGTGGAGCATCTCGGGGACTTGCTGTCCCACTGCCAGGAATGCGGTTTGGCAGGAGACTTCTTCATCTTCTGTTTGAAAGAGTTGA
CTCATGTGGCCTCGGAAAATGAAACAGAGTTAAAAACTGAGCCCTTCTCCAGCAAGAGCCTCTTGGAATTAGAGCAACATCAGACTCTTC
TTGTGGAAGGCCAAGAGCGGAAGCTGCTTGTCCTGCAGCTGATGGCTGTTCTGTGCGAGAGAATGTCTGAGCAGATATTCACAAACGTCA
CTCAGGTGGTGGACTTTGTAGCAGCAACATTGCAGAGAGCCTGTGCAAGCCTGGCCCATCAGGCAGAGAGCACCGTGGAATCACAGACGC
TGAGCATGTCCATGGGGCTGGTGGCTGTCATGCTAGGAGGAGCTGTTCAGTTGAAGTCAAGTGATTTTGCTGTTCTGAAGCAGTTGTTGC
CTCTGTTGGAGAAGGTATCCAACACATACCCTGATCCGGTCATCCAAGAACTCGCTGTTGATCTCCGCATCACCATCTCTACCCATGGAG
CCTTTGCCACTGAGGCCGTCAGCATGGCTGCCCAAAGTACACTGAACAGAAAAGATCTGGAAGGGAAAATAGAAGAGCAGCAACAAACCA
GTCATGAAAGACCCACTGATGTAGCTCATAGCCACCTTGAACAACAGCAGAGCCATGAGACAGCCCCCCAGACAGGCCTGCAGTCAAATG
CTCCAATCATTCCTCAAGGAGTCAATGAGCCCAGCACTACTACAAGTCAGAAATCTGGAAGCGTAACCACAGAACAGCTCCAAGAGGTTC
TTTTGTCAGCTTATGACCCTCAAATTCCAACACGGGCTGCTGCCCTGCGTACTCTTTCCCACTGGATAGAGCAGAGAGAAGCAAAAGCCC
TTGAGATGCAAGAGAAGCTTCTCAAGATATTCTTGGAAAACTTGGAACATGAAGACACTTTTGTATATCTATCTGCAATTCAGGGGGTTG
CCCTGCTGTCAGACGTCTATCCTGAGAAAATCTTGCCGGACTTGTTGGCTCAATATGACAGCAGCAAAGACAAGCACACACCAGAGACCA
GAATGAAAGTCGGGGAAGTCCTTATGCGAATCGTCAGGGCATTAGGAGACATGGTCTCAAAGTACCGAGAACCTTTGATCCATACCTTCC
TGAGGGGAGTGAGAGATCCTGATGGTGCTCACAGGGCCAGCAGCTTGGCCAACCTTGGGGAGCTGTGCCAGAGGCTGGACTTTCTGCTGG
GCTCCGTGGTCCATGAGGTAACAGCTTGCCTGATTGCTGTGGCCAAAACAGATGGTGAAGTTCAAGTACGCAGAGCTGCCATACATGTGG
TTGTGCTGCTGCTTCGGGGACTCAGCCAGAAAGCTACTGAGGTGCTGAGCGCCGTCCTCAAGGATCTCTACCACCTGCTGAAGCACGTAG
TGTGTCTGGAGCCCGATGACGTGGCCAAGCTCCATGCCCAGTTGGCCCTAGAAGAGCTGGATGACATCATGAAAAACTTCCTGTTCCCTC
CACAGAAGCTGGAGAAGAAGATCATGGTCCTGCCGTAGACCTGGCTCCAAGGACGTGGAGGAGGCAGGCAGGGCCAGGCACCCAGAGCCG
TGCCCAGGTCTTCCAGCAGGTGGCCCTGCTGCCTCTTGAGTGCTGGCAGCATGGCTGACCCTCGGGGTGGTTTTATGGTGCAGGTCACTT
GGGTCTTCAGGGTCCCTTCCGAGGGCATGTGTTCAGCACTCCCGCGTTCAGCCTGAGGGGTGTACAGTTAAGAGAAGACAGTTACAGATC
TCATTAATCTACATTTTTCACTGTCCTCTAGCATTGAAAGAAGGATGTCTACCTGGTGAAAGTATATTTTAACATGACTGATGGAATTTC
ACTAATTGCCCACTCTCTTGGAACTTGAGGAGAAGCGGTTGGCCACCCATATGTCACCTAGCTCTATATTCTTTCAGGCTGAGATTCTTC
TTCAGGAAAATGAGGAGCAGAACTGGCCACCCTTGGCTGCTCAAGAGGCATTTCAGAGTAGGAGATGCAGTTGGAGGTGGGGAGGGGAAG
GAAATAGTTATCAAATAATGCAAAATGGAATAAAGTTATCTTGGATGGAAAGAACAGGGCTAAATCTGGTCCTCTGGTGTCGAGATGGAA
AACTGTGGAGTTGAAGAGGCTCTGATGCCCAGAAAGGACAATCAAGCTGGTTGACTCTTCCAGAGAAGAAGGGTAAGCCCTGTATTTATC
CTCCCAGGCCATTCTTCTTCACTCCTGCTGCTGTTTGCAGAGAGTTGCCCTGATTATCAGGAGAAAAGAACCACGAGCATCCAGAGAGTT
TACATCCTGCCTTCTGTCCTCTGCTCCTTCAGAAAGATGAATGCCTAGACAATGGGTTCACACTGAATGCAGGCTGGAAAGAATGCATGC
TGGTGGCCTAATGCCAGGGCTGTTGAAACAATTTCAGATATAGCACTGTGGTCTCCACTTTATTTCTTTATATGTTTTGGCCGCTGCATT
TTGATTGCAGCTAAAAGAGATAACAGAAAGGAGATACTGGCTGGCTGCTTCATATTAGCCCTCTCTGTTGTCAACACCTTGATGAGGCCA
ACCCAGAGATGCTTGATCAGTCCTCAGCTTTGCAGGGCTAGGTACAGAATTTTATCACAGGATTTTATCACGCTCTCTGGGGTGACTAGA
TCCACAGGAACCAAAACGCAGTTTCCAAAAGCTCGAGTGACTGAAGGATCTATACACAAACATGGCTATTTGCTAGTTAACAACAGGATA
TTTCTCTCTGGCCAGATCACAGACATGGTTCTGAGTCAGATCTTCCTTGGTGGCATCCCTTTAAAGAGGCCATCTTATGAACAGGATCAC
AAGTGAGCTTAGTGAGCAGAGAGTTAGAACAAATCTAGCTAGGTGTGTTTAAGGAATATTTCCATTCAGCTAGTGTAGCTGGATTAATTT
CTATTCTCCAAATCAAGGATGTCTAGAAAATGGGCATTGTGGCTTTCAAATCTAAGAAGAATCTCCTTTGGGCCAGCTGGATGTACAATA

>99536_99536_6_WWP2-TANGO6_WWP2_chr16_69922152_ENST00000356003_TANGO6_chr16_68941346_ENST00000261778_length(amino acids)=843AA_BP=305
MASASSSRAGVALPFEKSQLTLKVVSAKPKVHNRQPRINSYVEVAVDGLPSETKKTGKRIGSSELLWNEIIILNVTAQSHLDLKVWSCHT
LRNELLGTASVNLSNVLKNNGGKMENMQLTLNLQTENKGSVVSGGELTIFLDGPTVDLGNVPNGSALTDGSQLPSRDSSGTAVAPENRHQ
PPSTNCFGGRSRTHRHSGASARTTPATGEQSPGARSRHRQPVKNSGHSGLANGTVNDEPTTATDPEEPSVVGVTSPPAAPLSVTPNPNTT
SLPAPATPAEGEEPSTSGTQQLPAAAQAPDALPAGDEDEDEALYQKVSSEQGRVEHLGDLLSHCQECGLAGDFFIFCLKELTHVASENET
ELKTEPFSSKSLLELEQHQTLLVEGQERKLLVLQLMAVLCERMSEQIFTNVTQVVDFVAATLQRACASLAHQAESTVESQTLSMSMGLVA
VMLGGAVQLKSSDFAVLKQLLPLLEKVSNTYPDPVIQELAVDLRITISTHGAFATEAVSMAAQSTLNRKDLEGKIEEQQQTSHERPTDVA
HSHLEQQQSHETAPQTGLQSNAPIIPQGVNEPSTTTSQKSGSVTTEQLQEVLLSAYDPQIPTRAAALRTLSHWIEQREAKALEMQEKLLK
IFLENLEHEDTFVYLSAIQGVALLSDVYPEKILPDLLAQYDSSKDKHTPETRMKVGEVLMRIVRALGDMVSKYREPLIHTFLRGVRDPDG
AHRASSLANLGELCQRLDFLLGSVVHEVTACLIAVAKTDGEVQVRRAAIHVVVLLLRGLSQKATEVLSAVLKDLYHLLKHVVCLEPDDVA

--------------------------------------------------------------
>99536_99536_7_WWP2-TANGO6_WWP2_chr16_69922152_ENST00000359154_TANGO6_chr16_68936231_ENST00000261778_length(transcript)=4329nt_BP=1015nt
GCGCGGTCACGTGACCCGGCCCGAGTGCGGGCGGTGGAAGGCGGAAGTAGGAGAGGAGTTCGGCGCCGCTTCTGTGGCCACGGCAGCTTC
ACGGTGATGATATGGCATCTGCCAGCTCTAGCCGGGCAGGAGTGGCCCTGCCTTTTGAGAAGTCTCAGCTCACTTTGAAAGTGGTGTCCG
CAAAGCCCAAGGTGCATAATCGTCAACCTCGAATTAACTCCTACGTGGAGGTGGCGGTGGATGGACTCCCCAGTGAGACCAAGAAGACTG
GGAAGCGCATTGGGAGCTCTGAGCTTCTCTGGAATGAGATCATCATTTTGAATGTCACGGCACAGAGTCATTTAGATTTAAAGGTCTGGA
GCTGCCATACCTTGAGAAATGAACTGCTAGGCACCGCATCTGTCAACCTCTCCAACGTCTTGAAGAACAATGGGGGCAAAATGGAGAACA
TGCAGCTGACCCTGAACCTGCAGACGGAGAACAAAGGCAGCGTTGTCTCAGGCGGAGAGCTGACAATTTTCCTGGACGGGCCAACTGTTG
ATCTGGGAAATGTGCCTAATGGCAGTGCCCTGACAGATGGATCACAGCTGCCTTCGAGAGACTCCAGTGGAACAGCAGTAGCTCCAGAGA
ACCGGCACCAGCCCCCCAGCACAAACTGCTTTGGTGGAAGATCCCGGACGCACAGACATTCGGGTGCTTCAGCCAGAACAACCCCAGCAA
CCGGCGAGCAAAGCCCCGGTGCTCGGAGCCGGCACCGCCAGCCCGTCAAGAACTCAGGCCACAGTGGCTTGGCCAATGGCACAGTGAATG
ATGAACCCACAACAGCCACTGATCCCGAAGAACCTTCCGTTGTTGGTGTGACGTCCCCACCTGCTGCACCCTTGAGTGTGACCCCGAATC
CCAACACGACTTCTCTCCCTGCCCCAGCCACACCGGCTGAAGGAGAGGAACCCAGCACTTCGGGTACACAGCAGCTCCCAGCGGCTGCCC
AGGCCCCCGACGCTCTGCCTGCTGGGTCACTTTGCCAAGAAATCTTATTATGGATTCTGGGGAAGCTGGAAAGGAAGAAGGCAATTGCCA
GCCTGAAAGGATTTGCAGGGTTGGACAAAGCTGTGCCCTCTCTCCATTCTCTGTGTCAGTTTAGAGTTGCCACTCAAGGTGGCATTATGA
TTACCATCAAAGAGGCCATTAGTGATGAAGATGAAGATGAAGCCCTGTACCAGAAGGTATCCTCTGAGCAGGGCCGGGTGGAGCATCTCG
GGGACTTGCTGTCCCACTGCCAGGAATGCGGTTTGGCAGGAGACTTCTTCATCTTCTGTTTGAAAGAGTTGACTCATGTGGCCTCGGAAA
ATGAAACAGAGTTAAAAACTGAGCCCTTCTCCAGCAAGAGCCTCTTGGAATTAGAGCAACATCAGACTCTTCTTGTGGAAGGCCAAGAGC
GGAAGCTGCTTGTCCTGCAGCTGATGGCTGTTCTGTGCGAGAGAATGTCTGAGCAGATATTCACAAACGTCACTCAGGTGGTGGACTTTG
TAGCAGCAACATTGCAGAGAGCCTGTGCAAGCCTGGCCCATCAGGCAGAGAGCACCGTGGAATCACAGACGCTGAGCATGTCCATGGGGC
TGGTGGCTGTCATGCTAGGAGGAGCTGTTCAGTTGAAGTCAAGTGATTTTGCTGTTCTGAAGCAGTTGTTGCCTCTGTTGGAGAAGGTAT
CCAACACATACCCTGATCCGGTCATCCAAGAACTCGCTGTTGATCTCCGCATCACCATCTCTACCCATGGAGCCTTTGCCACTGAGGCCG
TCAGCATGGCTGCCCAAAGTACACTGAACAGAAAAGATCTGGAAGGGAAAATAGAAGAGCAGCAACAAACCAGTCATGAAAGACCCACTG
ATGTAGCTCATAGCCACCTTGAACAACAGCAGAGCCATGAGACAGCCCCCCAGACAGGCCTGCAGTCAAATGCTCCAATCATTCCTCAAG
GAGTCAATGAGCCCAGCACTACTACAAGTCAGAAATCTGGAAGCGTAACCACAGAACAGCTCCAAGAGGTTCTTTTGTCAGCTTATGACC
CTCAAATTCCAACACGGGCTGCTGCCCTGCGTACTCTTTCCCACTGGATAGAGCAGAGAGAAGCAAAAGCCCTTGAGATGCAAGAGAAGC
TTCTCAAGATATTCTTGGAAAACTTGGAACATGAAGACACTTTTGTATATCTATCTGCAATTCAGGGGGTTGCCCTGCTGTCAGACGTCT
ATCCTGAGAAAATCTTGCCGGACTTGTTGGCTCAATATGACAGCAGCAAAGACAAGCACACACCAGAGACCAGAATGAAAGTCGGGGAAG
TCCTTATGCGAATCGTCAGGGCATTAGGAGACATGGTCTCAAAGTACCGAGAACCTTTGATCCATACCTTCCTGAGGGGAGTGAGAGATC
CTGATGGTGCTCACAGGGCCAGCAGCTTGGCCAACCTTGGGGAGCTGTGCCAGAGGCTGGACTTTCTGCTGGGCTCCGTGGTCCATGAGG
TAACAGCTTGCCTGATTGCTGTGGCCAAAACAGATGGTGAAGTTCAAGTACGCAGAGCTGCCATACATGTGGTTGTGCTGCTGCTTCGGG
GACTCAGCCAGAAAGCTACTGAGGTGCTGAGCGCCGTCCTCAAGGATCTCTACCACCTGCTGAAGCACGTAGTGTGTCTGGAGCCCGATG
ACGTGGCCAAGCTCCATGCCCAGTTGGCCCTAGAAGAGCTGGATGACATCATGAAAAACTTCCTGTTCCCTCCACAGAAGCTGGAGAAGA
AGATCATGGTCCTGCCGTAGACCTGGCTCCAAGGACGTGGAGGAGGCAGGCAGGGCCAGGCACCCAGAGCCGTGCCCAGGTCTTCCAGCA
GGTGGCCCTGCTGCCTCTTGAGTGCTGGCAGCATGGCTGACCCTCGGGGTGGTTTTATGGTGCAGGTCACTTGGGTCTTCAGGGTCCCTT
CCGAGGGCATGTGTTCAGCACTCCCGCGTTCAGCCTGAGGGGTGTACAGTTAAGAGAAGACAGTTACAGATCTCATTAATCTACATTTTT
CACTGTCCTCTAGCATTGAAAGAAGGATGTCTACCTGGTGAAAGTATATTTTAACATGACTGATGGAATTTCACTAATTGCCCACTCTCT
TGGAACTTGAGGAGAAGCGGTTGGCCACCCATATGTCACCTAGCTCTATATTCTTTCAGGCTGAGATTCTTCTTCAGGAAAATGAGGAGC
AGAACTGGCCACCCTTGGCTGCTCAAGAGGCATTTCAGAGTAGGAGATGCAGTTGGAGGTGGGGAGGGGAAGGAAATAGTTATCAAATAA
TGCAAAATGGAATAAAGTTATCTTGGATGGAAAGAACAGGGCTAAATCTGGTCCTCTGGTGTCGAGATGGAAAACTGTGGAGTTGAAGAG
GCTCTGATGCCCAGAAAGGACAATCAAGCTGGTTGACTCTTCCAGAGAAGAAGGGTAAGCCCTGTATTTATCCTCCCAGGCCATTCTTCT
TCACTCCTGCTGCTGTTTGCAGAGAGTTGCCCTGATTATCAGGAGAAAAGAACCACGAGCATCCAGAGAGTTTACATCCTGCCTTCTGTC
CTCTGCTCCTTCAGAAAGATGAATGCCTAGACAATGGGTTCACACTGAATGCAGGCTGGAAAGAATGCATGCTGGTGGCCTAATGCCAGG
GCTGTTGAAACAATTTCAGATATAGCACTGTGGTCTCCACTTTATTTCTTTATATGTTTTGGCCGCTGCATTTTGATTGCAGCTAAAAGA
GATAACAGAAAGGAGATACTGGCTGGCTGCTTCATATTAGCCCTCTCTGTTGTCAACACCTTGATGAGGCCAACCCAGAGATGCTTGATC
AGTCCTCAGCTTTGCAGGGCTAGGTACAGAATTTTATCACAGGATTTTATCACGCTCTCTGGGGTGACTAGATCCACAGGAACCAAAACG
CAGTTTCCAAAAGCTCGAGTGACTGAAGGATCTATACACAAACATGGCTATTTGCTAGTTAACAACAGGATATTTCTCTCTGGCCAGATC
ACAGACATGGTTCTGAGTCAGATCTTCCTTGGTGGCATCCCTTTAAAGAGGCCATCTTATGAACAGGATCACAAGTGAGCTTAGTGAGCA
GAGAGTTAGAACAAATCTAGCTAGGTGTGTTTAAGGAATATTTCCATTCAGCTAGTGTAGCTGGATTAATTTCTATTCTCCAAATCAAGG
ATGTCTAGAAAATGGGCATTGTGGCTTTCAAATCTAAGAAGAATCTCCTTTGGGCCAGCTGGATGTACAATAAAAATGCTTGTTTCTTGG

>99536_99536_7_WWP2-TANGO6_WWP2_chr16_69922152_ENST00000359154_TANGO6_chr16_68936231_ENST00000261778_length(amino acids)=912AA_BP=313
MWPRQLHGDDMASASSSRAGVALPFEKSQLTLKVVSAKPKVHNRQPRINSYVEVAVDGLPSETKKTGKRIGSSELLWNEIIILNVTAQSH
LDLKVWSCHTLRNELLGTASVNLSNVLKNNGGKMENMQLTLNLQTENKGSVVSGGELTIFLDGPTVDLGNVPNGSALTDGSQLPSRDSSG
TAVAPENRHQPPSTNCFGGRSRTHRHSGASARTTPATGEQSPGARSRHRQPVKNSGHSGLANGTVNDEPTTATDPEEPSVVGVTSPPAAP
LSVTPNPNTTSLPAPATPAEGEEPSTSGTQQLPAAAQAPDALPAGSLCQEILLWILGKLERKKAIASLKGFAGLDKAVPSLHSLCQFRVA
TQGGIMITIKEAISDEDEDEALYQKVSSEQGRVEHLGDLLSHCQECGLAGDFFIFCLKELTHVASENETELKTEPFSSKSLLELEQHQTL
LVEGQERKLLVLQLMAVLCERMSEQIFTNVTQVVDFVAATLQRACASLAHQAESTVESQTLSMSMGLVAVMLGGAVQLKSSDFAVLKQLL
PLLEKVSNTYPDPVIQELAVDLRITISTHGAFATEAVSMAAQSTLNRKDLEGKIEEQQQTSHERPTDVAHSHLEQQQSHETAPQTGLQSN
APIIPQGVNEPSTTTSQKSGSVTTEQLQEVLLSAYDPQIPTRAAALRTLSHWIEQREAKALEMQEKLLKIFLENLEHEDTFVYLSAIQGV
ALLSDVYPEKILPDLLAQYDSSKDKHTPETRMKVGEVLMRIVRALGDMVSKYREPLIHTFLRGVRDPDGAHRASSLANLGELCQRLDFLL
GSVVHEVTACLIAVAKTDGEVQVRRAAIHVVVLLLRGLSQKATEVLSAVLKDLYHLLKHVVCLEPDDVAKLHAQLALEELDDIMKNFLFP

--------------------------------------------------------------
>99536_99536_8_WWP2-TANGO6_WWP2_chr16_69922152_ENST00000359154_TANGO6_chr16_68941346_ENST00000261778_length(transcript)=4152nt_BP=1015nt
GCGCGGTCACGTGACCCGGCCCGAGTGCGGGCGGTGGAAGGCGGAAGTAGGAGAGGAGTTCGGCGCCGCTTCTGTGGCCACGGCAGCTTC
ACGGTGATGATATGGCATCTGCCAGCTCTAGCCGGGCAGGAGTGGCCCTGCCTTTTGAGAAGTCTCAGCTCACTTTGAAAGTGGTGTCCG
CAAAGCCCAAGGTGCATAATCGTCAACCTCGAATTAACTCCTACGTGGAGGTGGCGGTGGATGGACTCCCCAGTGAGACCAAGAAGACTG
GGAAGCGCATTGGGAGCTCTGAGCTTCTCTGGAATGAGATCATCATTTTGAATGTCACGGCACAGAGTCATTTAGATTTAAAGGTCTGGA
GCTGCCATACCTTGAGAAATGAACTGCTAGGCACCGCATCTGTCAACCTCTCCAACGTCTTGAAGAACAATGGGGGCAAAATGGAGAACA
TGCAGCTGACCCTGAACCTGCAGACGGAGAACAAAGGCAGCGTTGTCTCAGGCGGAGAGCTGACAATTTTCCTGGACGGGCCAACTGTTG
ATCTGGGAAATGTGCCTAATGGCAGTGCCCTGACAGATGGATCACAGCTGCCTTCGAGAGACTCCAGTGGAACAGCAGTAGCTCCAGAGA
ACCGGCACCAGCCCCCCAGCACAAACTGCTTTGGTGGAAGATCCCGGACGCACAGACATTCGGGTGCTTCAGCCAGAACAACCCCAGCAA
CCGGCGAGCAAAGCCCCGGTGCTCGGAGCCGGCACCGCCAGCCCGTCAAGAACTCAGGCCACAGTGGCTTGGCCAATGGCACAGTGAATG
ATGAACCCACAACAGCCACTGATCCCGAAGAACCTTCCGTTGTTGGTGTGACGTCCCCACCTGCTGCACCCTTGAGTGTGACCCCGAATC
CCAACACGACTTCTCTCCCTGCCCCAGCCACACCGGCTGAAGGAGAGGAACCCAGCACTTCGGGTACACAGCAGCTCCCAGCGGCTGCCC
AGGCCCCCGACGCTCTGCCTGCTGGTGATGAAGATGAAGATGAAGCCCTGTACCAGAAGGTATCCTCTGAGCAGGGCCGGGTGGAGCATC
TCGGGGACTTGCTGTCCCACTGCCAGGAATGCGGTTTGGCAGGAGACTTCTTCATCTTCTGTTTGAAAGAGTTGACTCATGTGGCCTCGG
AAAATGAAACAGAGTTAAAAACTGAGCCCTTCTCCAGCAAGAGCCTCTTGGAATTAGAGCAACATCAGACTCTTCTTGTGGAAGGCCAAG
AGCGGAAGCTGCTTGTCCTGCAGCTGATGGCTGTTCTGTGCGAGAGAATGTCTGAGCAGATATTCACAAACGTCACTCAGGTGGTGGACT
TTGTAGCAGCAACATTGCAGAGAGCCTGTGCAAGCCTGGCCCATCAGGCAGAGAGCACCGTGGAATCACAGACGCTGAGCATGTCCATGG
GGCTGGTGGCTGTCATGCTAGGAGGAGCTGTTCAGTTGAAGTCAAGTGATTTTGCTGTTCTGAAGCAGTTGTTGCCTCTGTTGGAGAAGG
TATCCAACACATACCCTGATCCGGTCATCCAAGAACTCGCTGTTGATCTCCGCATCACCATCTCTACCCATGGAGCCTTTGCCACTGAGG
CCGTCAGCATGGCTGCCCAAAGTACACTGAACAGAAAAGATCTGGAAGGGAAAATAGAAGAGCAGCAACAAACCAGTCATGAAAGACCCA
CTGATGTAGCTCATAGCCACCTTGAACAACAGCAGAGCCATGAGACAGCCCCCCAGACAGGCCTGCAGTCAAATGCTCCAATCATTCCTC
AAGGAGTCAATGAGCCCAGCACTACTACAAGTCAGAAATCTGGAAGCGTAACCACAGAACAGCTCCAAGAGGTTCTTTTGTCAGCTTATG
ACCCTCAAATTCCAACACGGGCTGCTGCCCTGCGTACTCTTTCCCACTGGATAGAGCAGAGAGAAGCAAAAGCCCTTGAGATGCAAGAGA
AGCTTCTCAAGATATTCTTGGAAAACTTGGAACATGAAGACACTTTTGTATATCTATCTGCAATTCAGGGGGTTGCCCTGCTGTCAGACG
TCTATCCTGAGAAAATCTTGCCGGACTTGTTGGCTCAATATGACAGCAGCAAAGACAAGCACACACCAGAGACCAGAATGAAAGTCGGGG
AAGTCCTTATGCGAATCGTCAGGGCATTAGGAGACATGGTCTCAAAGTACCGAGAACCTTTGATCCATACCTTCCTGAGGGGAGTGAGAG
ATCCTGATGGTGCTCACAGGGCCAGCAGCTTGGCCAACCTTGGGGAGCTGTGCCAGAGGCTGGACTTTCTGCTGGGCTCCGTGGTCCATG
AGGTAACAGCTTGCCTGATTGCTGTGGCCAAAACAGATGGTGAAGTTCAAGTACGCAGAGCTGCCATACATGTGGTTGTGCTGCTGCTTC
GGGGACTCAGCCAGAAAGCTACTGAGGTGCTGAGCGCCGTCCTCAAGGATCTCTACCACCTGCTGAAGCACGTAGTGTGTCTGGAGCCCG
ATGACGTGGCCAAGCTCCATGCCCAGTTGGCCCTAGAAGAGCTGGATGACATCATGAAAAACTTCCTGTTCCCTCCACAGAAGCTGGAGA
AGAAGATCATGGTCCTGCCGTAGACCTGGCTCCAAGGACGTGGAGGAGGCAGGCAGGGCCAGGCACCCAGAGCCGTGCCCAGGTCTTCCA
GCAGGTGGCCCTGCTGCCTCTTGAGTGCTGGCAGCATGGCTGACCCTCGGGGTGGTTTTATGGTGCAGGTCACTTGGGTCTTCAGGGTCC
CTTCCGAGGGCATGTGTTCAGCACTCCCGCGTTCAGCCTGAGGGGTGTACAGTTAAGAGAAGACAGTTACAGATCTCATTAATCTACATT
TTTCACTGTCCTCTAGCATTGAAAGAAGGATGTCTACCTGGTGAAAGTATATTTTAACATGACTGATGGAATTTCACTAATTGCCCACTC
TCTTGGAACTTGAGGAGAAGCGGTTGGCCACCCATATGTCACCTAGCTCTATATTCTTTCAGGCTGAGATTCTTCTTCAGGAAAATGAGG
AGCAGAACTGGCCACCCTTGGCTGCTCAAGAGGCATTTCAGAGTAGGAGATGCAGTTGGAGGTGGGGAGGGGAAGGAAATAGTTATCAAA
TAATGCAAAATGGAATAAAGTTATCTTGGATGGAAAGAACAGGGCTAAATCTGGTCCTCTGGTGTCGAGATGGAAAACTGTGGAGTTGAA
GAGGCTCTGATGCCCAGAAAGGACAATCAAGCTGGTTGACTCTTCCAGAGAAGAAGGGTAAGCCCTGTATTTATCCTCCCAGGCCATTCT
TCTTCACTCCTGCTGCTGTTTGCAGAGAGTTGCCCTGATTATCAGGAGAAAAGAACCACGAGCATCCAGAGAGTTTACATCCTGCCTTCT
GTCCTCTGCTCCTTCAGAAAGATGAATGCCTAGACAATGGGTTCACACTGAATGCAGGCTGGAAAGAATGCATGCTGGTGGCCTAATGCC
AGGGCTGTTGAAACAATTTCAGATATAGCACTGTGGTCTCCACTTTATTTCTTTATATGTTTTGGCCGCTGCATTTTGATTGCAGCTAAA
AGAGATAACAGAAAGGAGATACTGGCTGGCTGCTTCATATTAGCCCTCTCTGTTGTCAACACCTTGATGAGGCCAACCCAGAGATGCTTG
ATCAGTCCTCAGCTTTGCAGGGCTAGGTACAGAATTTTATCACAGGATTTTATCACGCTCTCTGGGGTGACTAGATCCACAGGAACCAAA
ACGCAGTTTCCAAAAGCTCGAGTGACTGAAGGATCTATACACAAACATGGCTATTTGCTAGTTAACAACAGGATATTTCTCTCTGGCCAG
ATCACAGACATGGTTCTGAGTCAGATCTTCCTTGGTGGCATCCCTTTAAAGAGGCCATCTTATGAACAGGATCACAAGTGAGCTTAGTGA
GCAGAGAGTTAGAACAAATCTAGCTAGGTGTGTTTAAGGAATATTTCCATTCAGCTAGTGTAGCTGGATTAATTTCTATTCTCCAAATCA
AGGATGTCTAGAAAATGGGCATTGTGGCTTTCAAATCTAAGAAGAATCTCCTTTGGGCCAGCTGGATGTACAATAAAAATGCTTGTTTCT

>99536_99536_8_WWP2-TANGO6_WWP2_chr16_69922152_ENST00000359154_TANGO6_chr16_68941346_ENST00000261778_length(amino acids)=853AA_BP=315
MWPRQLHGDDMASASSSRAGVALPFEKSQLTLKVVSAKPKVHNRQPRINSYVEVAVDGLPSETKKTGKRIGSSELLWNEIIILNVTAQSH
LDLKVWSCHTLRNELLGTASVNLSNVLKNNGGKMENMQLTLNLQTENKGSVVSGGELTIFLDGPTVDLGNVPNGSALTDGSQLPSRDSSG
TAVAPENRHQPPSTNCFGGRSRTHRHSGASARTTPATGEQSPGARSRHRQPVKNSGHSGLANGTVNDEPTTATDPEEPSVVGVTSPPAAP
LSVTPNPNTTSLPAPATPAEGEEPSTSGTQQLPAAAQAPDALPAGDEDEDEALYQKVSSEQGRVEHLGDLLSHCQECGLAGDFFIFCLKE
LTHVASENETELKTEPFSSKSLLELEQHQTLLVEGQERKLLVLQLMAVLCERMSEQIFTNVTQVVDFVAATLQRACASLAHQAESTVESQ
TLSMSMGLVAVMLGGAVQLKSSDFAVLKQLLPLLEKVSNTYPDPVIQELAVDLRITISTHGAFATEAVSMAAQSTLNRKDLEGKIEEQQQ
TSHERPTDVAHSHLEQQQSHETAPQTGLQSNAPIIPQGVNEPSTTTSQKSGSVTTEQLQEVLLSAYDPQIPTRAAALRTLSHWIEQREAK
ALEMQEKLLKIFLENLEHEDTFVYLSAIQGVALLSDVYPEKILPDLLAQYDSSKDKHTPETRMKVGEVLMRIVRALGDMVSKYREPLIHT
FLRGVRDPDGAHRASSLANLGELCQRLDFLLGSVVHEVTACLIAVAKTDGEVQVRRAAIHVVVLLLRGLSQKATEVLSAVLKDLYHLLKH

--------------------------------------------------------------
>99536_99536_9_WWP2-TANGO6_WWP2_chr16_69922152_ENST00000448661_TANGO6_chr16_68936231_ENST00000261778_length(transcript)=4306nt_BP=992nt
TTCGGCGCCGCTTCTGTGGCCACGGCAGGTAGCGAGCGCTGGCGCGGGGGGCGCGTCTTACAGCTTCACGGTGATGATATGGCATCTGCC
AGCTCTAGCCGGGCAGGAGTGGCCCTGCCTTTTGAGAAGTCTCAGCTCACTTTGAAAGTGGTGTCCGCAAAGCCCAAGGTGCATAATCGT
CAACCTCGAATTAACTCCTACGTGGAGGTGGCGGTGGATGGACTCCCCAGTGAGACCAAGAAGACTGGGAAGCGCATTGGGAGCTCTGAG
CTTCTCTGGAATGAGATCATCATTTTGAATGTCACGGCACAGAGTCATTTAGATTTAAAGGTCTGGAGCTGCCATACCTTGAGAAATGAA
CTGCTAGGCACCGCATCTGTCAACCTCTCCAACGTCTTGAAGAACAATGGGGGCAAAATGGAGAACATGCAGCTGACCCTGAACCTGCAG
ACGGAGAACAAAGGCAGCGTTGTCTCAGGCGGAGAGCTGACAATTTTCCTGGACGGGCCAACTGTTGATCTGGGAAATGTGCCTAATGGC
AGTGCCCTGACAGATGGATCACAGCTGCCTTCGAGAGACTCCAGTGGAACAGCAGTAGCTCCAGAGAACCGGCACCAGCCCCCCAGCACA
AACTGCTTTGGTGGAAGATCCCGGACGCACAGACATTCGGGTGCTTCAGCCAGAACAACCCCAGCAACCGGCGAGCAAAGCCCCGGTGCT
CGGAGCCGGCACCGCCAGCCCGTCAAGAACTCAGGCCACAGTGGCTTGGCCAATGGCACAGTGAATGATGAACCCACAACAGCCACTGAT
CCCGAAGAACCTTCCGTTGTTGGTGTGACGTCCCCACCTGCTGCACCCTTGAGTGTGACCCCGAATCCCAACACGACTTCTCTCCCTGCC
CCAGCCACACCGGCTGAAGGAGAGGAACCCAGCACTTCGGGTACACAGCAGCTCCCAGCGGCTGCCCAGGCCCCCGACGCTCTGCCTGCT
GGGTCACTTTGCCAAGAAATCTTATTATGGATTCTGGGGAAGCTGGAAAGGAAGAAGGCAATTGCCAGCCTGAAAGGATTTGCAGGGTTG
GACAAAGCTGTGCCCTCTCTCCATTCTCTGTGTCAGTTTAGAGTTGCCACTCAAGGTGGCATTATGATTACCATCAAAGAGGCCATTAGT
GATGAAGATGAAGATGAAGCCCTGTACCAGAAGGTATCCTCTGAGCAGGGCCGGGTGGAGCATCTCGGGGACTTGCTGTCCCACTGCCAG
GAATGCGGTTTGGCAGGAGACTTCTTCATCTTCTGTTTGAAAGAGTTGACTCATGTGGCCTCGGAAAATGAAACAGAGTTAAAAACTGAG
CCCTTCTCCAGCAAGAGCCTCTTGGAATTAGAGCAACATCAGACTCTTCTTGTGGAAGGCCAAGAGCGGAAGCTGCTTGTCCTGCAGCTG
ATGGCTGTTCTGTGCGAGAGAATGTCTGAGCAGATATTCACAAACGTCACTCAGGTGGTGGACTTTGTAGCAGCAACATTGCAGAGAGCC
TGTGCAAGCCTGGCCCATCAGGCAGAGAGCACCGTGGAATCACAGACGCTGAGCATGTCCATGGGGCTGGTGGCTGTCATGCTAGGAGGA
GCTGTTCAGTTGAAGTCAAGTGATTTTGCTGTTCTGAAGCAGTTGTTGCCTCTGTTGGAGAAGGTATCCAACACATACCCTGATCCGGTC
ATCCAAGAACTCGCTGTTGATCTCCGCATCACCATCTCTACCCATGGAGCCTTTGCCACTGAGGCCGTCAGCATGGCTGCCCAAAGTACA
CTGAACAGAAAAGATCTGGAAGGGAAAATAGAAGAGCAGCAACAAACCAGTCATGAAAGACCCACTGATGTAGCTCATAGCCACCTTGAA
CAACAGCAGAGCCATGAGACAGCCCCCCAGACAGGCCTGCAGTCAAATGCTCCAATCATTCCTCAAGGAGTCAATGAGCCCAGCACTACT
ACAAGTCAGAAATCTGGAAGCGTAACCACAGAACAGCTCCAAGAGGTTCTTTTGTCAGCTTATGACCCTCAAATTCCAACACGGGCTGCT
GCCCTGCGTACTCTTTCCCACTGGATAGAGCAGAGAGAAGCAAAAGCCCTTGAGATGCAAGAGAAGCTTCTCAAGATATTCTTGGAAAAC
TTGGAACATGAAGACACTTTTGTATATCTATCTGCAATTCAGGGGGTTGCCCTGCTGTCAGACGTCTATCCTGAGAAAATCTTGCCGGAC
TTGTTGGCTCAATATGACAGCAGCAAAGACAAGCACACACCAGAGACCAGAATGAAAGTCGGGGAAGTCCTTATGCGAATCGTCAGGGCA
TTAGGAGACATGGTCTCAAAGTACCGAGAACCTTTGATCCATACCTTCCTGAGGGGAGTGAGAGATCCTGATGGTGCTCACAGGGCCAGC
AGCTTGGCCAACCTTGGGGAGCTGTGCCAGAGGCTGGACTTTCTGCTGGGCTCCGTGGTCCATGAGGTAACAGCTTGCCTGATTGCTGTG
GCCAAAACAGATGGTGAAGTTCAAGTACGCAGAGCTGCCATACATGTGGTTGTGCTGCTGCTTCGGGGACTCAGCCAGAAAGCTACTGAG
GTGCTGAGCGCCGTCCTCAAGGATCTCTACCACCTGCTGAAGCACGTAGTGTGTCTGGAGCCCGATGACGTGGCCAAGCTCCATGCCCAG
TTGGCCCTAGAAGAGCTGGATGACATCATGAAAAACTTCCTGTTCCCTCCACAGAAGCTGGAGAAGAAGATCATGGTCCTGCCGTAGACC
TGGCTCCAAGGACGTGGAGGAGGCAGGCAGGGCCAGGCACCCAGAGCCGTGCCCAGGTCTTCCAGCAGGTGGCCCTGCTGCCTCTTGAGT
GCTGGCAGCATGGCTGACCCTCGGGGTGGTTTTATGGTGCAGGTCACTTGGGTCTTCAGGGTCCCTTCCGAGGGCATGTGTTCAGCACTC
CCGCGTTCAGCCTGAGGGGTGTACAGTTAAGAGAAGACAGTTACAGATCTCATTAATCTACATTTTTCACTGTCCTCTAGCATTGAAAGA
AGGATGTCTACCTGGTGAAAGTATATTTTAACATGACTGATGGAATTTCACTAATTGCCCACTCTCTTGGAACTTGAGGAGAAGCGGTTG
GCCACCCATATGTCACCTAGCTCTATATTCTTTCAGGCTGAGATTCTTCTTCAGGAAAATGAGGAGCAGAACTGGCCACCCTTGGCTGCT
CAAGAGGCATTTCAGAGTAGGAGATGCAGTTGGAGGTGGGGAGGGGAAGGAAATAGTTATCAAATAATGCAAAATGGAATAAAGTTATCT
TGGATGGAAAGAACAGGGCTAAATCTGGTCCTCTGGTGTCGAGATGGAAAACTGTGGAGTTGAAGAGGCTCTGATGCCCAGAAAGGACAA
TCAAGCTGGTTGACTCTTCCAGAGAAGAAGGGTAAGCCCTGTATTTATCCTCCCAGGCCATTCTTCTTCACTCCTGCTGCTGTTTGCAGA
GAGTTGCCCTGATTATCAGGAGAAAAGAACCACGAGCATCCAGAGAGTTTACATCCTGCCTTCTGTCCTCTGCTCCTTCAGAAAGATGAA
TGCCTAGACAATGGGTTCACACTGAATGCAGGCTGGAAAGAATGCATGCTGGTGGCCTAATGCCAGGGCTGTTGAAACAATTTCAGATAT
AGCACTGTGGTCTCCACTTTATTTCTTTATATGTTTTGGCCGCTGCATTTTGATTGCAGCTAAAAGAGATAACAGAAAGGAGATACTGGC
TGGCTGCTTCATATTAGCCCTCTCTGTTGTCAACACCTTGATGAGGCCAACCCAGAGATGCTTGATCAGTCCTCAGCTTTGCAGGGCTAG
GTACAGAATTTTATCACAGGATTTTATCACGCTCTCTGGGGTGACTAGATCCACAGGAACCAAAACGCAGTTTCCAAAAGCTCGAGTGAC
TGAAGGATCTATACACAAACATGGCTATTTGCTAGTTAACAACAGGATATTTCTCTCTGGCCAGATCACAGACATGGTTCTGAGTCAGAT
CTTCCTTGGTGGCATCCCTTTAAAGAGGCCATCTTATGAACAGGATCACAAGTGAGCTTAGTGAGCAGAGAGTTAGAACAAATCTAGCTA
GGTGTGTTTAAGGAATATTTCCATTCAGCTAGTGTAGCTGGATTAATTTCTATTCTCCAAATCAAGGATGTCTAGAAAATGGGCATTGTG

>99536_99536_9_WWP2-TANGO6_WWP2_chr16_69922152_ENST00000448661_TANGO6_chr16_68936231_ENST00000261778_length(amino acids)=902AA_BP=303
MASASSSRAGVALPFEKSQLTLKVVSAKPKVHNRQPRINSYVEVAVDGLPSETKKTGKRIGSSELLWNEIIILNVTAQSHLDLKVWSCHT
LRNELLGTASVNLSNVLKNNGGKMENMQLTLNLQTENKGSVVSGGELTIFLDGPTVDLGNVPNGSALTDGSQLPSRDSSGTAVAPENRHQ
PPSTNCFGGRSRTHRHSGASARTTPATGEQSPGARSRHRQPVKNSGHSGLANGTVNDEPTTATDPEEPSVVGVTSPPAAPLSVTPNPNTT
SLPAPATPAEGEEPSTSGTQQLPAAAQAPDALPAGSLCQEILLWILGKLERKKAIASLKGFAGLDKAVPSLHSLCQFRVATQGGIMITIK
EAISDEDEDEALYQKVSSEQGRVEHLGDLLSHCQECGLAGDFFIFCLKELTHVASENETELKTEPFSSKSLLELEQHQTLLVEGQERKLL
VLQLMAVLCERMSEQIFTNVTQVVDFVAATLQRACASLAHQAESTVESQTLSMSMGLVAVMLGGAVQLKSSDFAVLKQLLPLLEKVSNTY
PDPVIQELAVDLRITISTHGAFATEAVSMAAQSTLNRKDLEGKIEEQQQTSHERPTDVAHSHLEQQQSHETAPQTGLQSNAPIIPQGVNE
PSTTTSQKSGSVTTEQLQEVLLSAYDPQIPTRAAALRTLSHWIEQREAKALEMQEKLLKIFLENLEHEDTFVYLSAIQGVALLSDVYPEK
ILPDLLAQYDSSKDKHTPETRMKVGEVLMRIVRALGDMVSKYREPLIHTFLRGVRDPDGAHRASSLANLGELCQRLDFLLGSVVHEVTAC
LIAVAKTDGEVQVRRAAIHVVVLLLRGLSQKATEVLSAVLKDLYHLLKHVVCLEPDDVAKLHAQLALEELDDIMKNFLFPPQKLEKKIMV

--------------------------------------------------------------
>99536_99536_10_WWP2-TANGO6_WWP2_chr16_69922152_ENST00000448661_TANGO6_chr16_68941346_ENST00000261778_length(transcript)=4129nt_BP=992nt
TTCGGCGCCGCTTCTGTGGCCACGGCAGGTAGCGAGCGCTGGCGCGGGGGGCGCGTCTTACAGCTTCACGGTGATGATATGGCATCTGCC
AGCTCTAGCCGGGCAGGAGTGGCCCTGCCTTTTGAGAAGTCTCAGCTCACTTTGAAAGTGGTGTCCGCAAAGCCCAAGGTGCATAATCGT
CAACCTCGAATTAACTCCTACGTGGAGGTGGCGGTGGATGGACTCCCCAGTGAGACCAAGAAGACTGGGAAGCGCATTGGGAGCTCTGAG
CTTCTCTGGAATGAGATCATCATTTTGAATGTCACGGCACAGAGTCATTTAGATTTAAAGGTCTGGAGCTGCCATACCTTGAGAAATGAA
CTGCTAGGCACCGCATCTGTCAACCTCTCCAACGTCTTGAAGAACAATGGGGGCAAAATGGAGAACATGCAGCTGACCCTGAACCTGCAG
ACGGAGAACAAAGGCAGCGTTGTCTCAGGCGGAGAGCTGACAATTTTCCTGGACGGGCCAACTGTTGATCTGGGAAATGTGCCTAATGGC
AGTGCCCTGACAGATGGATCACAGCTGCCTTCGAGAGACTCCAGTGGAACAGCAGTAGCTCCAGAGAACCGGCACCAGCCCCCCAGCACA
AACTGCTTTGGTGGAAGATCCCGGACGCACAGACATTCGGGTGCTTCAGCCAGAACAACCCCAGCAACCGGCGAGCAAAGCCCCGGTGCT
CGGAGCCGGCACCGCCAGCCCGTCAAGAACTCAGGCCACAGTGGCTTGGCCAATGGCACAGTGAATGATGAACCCACAACAGCCACTGAT
CCCGAAGAACCTTCCGTTGTTGGTGTGACGTCCCCACCTGCTGCACCCTTGAGTGTGACCCCGAATCCCAACACGACTTCTCTCCCTGCC
CCAGCCACACCGGCTGAAGGAGAGGAACCCAGCACTTCGGGTACACAGCAGCTCCCAGCGGCTGCCCAGGCCCCCGACGCTCTGCCTGCT
GGTGATGAAGATGAAGATGAAGCCCTGTACCAGAAGGTATCCTCTGAGCAGGGCCGGGTGGAGCATCTCGGGGACTTGCTGTCCCACTGC
CAGGAATGCGGTTTGGCAGGAGACTTCTTCATCTTCTGTTTGAAAGAGTTGACTCATGTGGCCTCGGAAAATGAAACAGAGTTAAAAACT
GAGCCCTTCTCCAGCAAGAGCCTCTTGGAATTAGAGCAACATCAGACTCTTCTTGTGGAAGGCCAAGAGCGGAAGCTGCTTGTCCTGCAG
CTGATGGCTGTTCTGTGCGAGAGAATGTCTGAGCAGATATTCACAAACGTCACTCAGGTGGTGGACTTTGTAGCAGCAACATTGCAGAGA
GCCTGTGCAAGCCTGGCCCATCAGGCAGAGAGCACCGTGGAATCACAGACGCTGAGCATGTCCATGGGGCTGGTGGCTGTCATGCTAGGA
GGAGCTGTTCAGTTGAAGTCAAGTGATTTTGCTGTTCTGAAGCAGTTGTTGCCTCTGTTGGAGAAGGTATCCAACACATACCCTGATCCG
GTCATCCAAGAACTCGCTGTTGATCTCCGCATCACCATCTCTACCCATGGAGCCTTTGCCACTGAGGCCGTCAGCATGGCTGCCCAAAGT
ACACTGAACAGAAAAGATCTGGAAGGGAAAATAGAAGAGCAGCAACAAACCAGTCATGAAAGACCCACTGATGTAGCTCATAGCCACCTT
GAACAACAGCAGAGCCATGAGACAGCCCCCCAGACAGGCCTGCAGTCAAATGCTCCAATCATTCCTCAAGGAGTCAATGAGCCCAGCACT
ACTACAAGTCAGAAATCTGGAAGCGTAACCACAGAACAGCTCCAAGAGGTTCTTTTGTCAGCTTATGACCCTCAAATTCCAACACGGGCT
GCTGCCCTGCGTACTCTTTCCCACTGGATAGAGCAGAGAGAAGCAAAAGCCCTTGAGATGCAAGAGAAGCTTCTCAAGATATTCTTGGAA
AACTTGGAACATGAAGACACTTTTGTATATCTATCTGCAATTCAGGGGGTTGCCCTGCTGTCAGACGTCTATCCTGAGAAAATCTTGCCG
GACTTGTTGGCTCAATATGACAGCAGCAAAGACAAGCACACACCAGAGACCAGAATGAAAGTCGGGGAAGTCCTTATGCGAATCGTCAGG
GCATTAGGAGACATGGTCTCAAAGTACCGAGAACCTTTGATCCATACCTTCCTGAGGGGAGTGAGAGATCCTGATGGTGCTCACAGGGCC
AGCAGCTTGGCCAACCTTGGGGAGCTGTGCCAGAGGCTGGACTTTCTGCTGGGCTCCGTGGTCCATGAGGTAACAGCTTGCCTGATTGCT
GTGGCCAAAACAGATGGTGAAGTTCAAGTACGCAGAGCTGCCATACATGTGGTTGTGCTGCTGCTTCGGGGACTCAGCCAGAAAGCTACT
GAGGTGCTGAGCGCCGTCCTCAAGGATCTCTACCACCTGCTGAAGCACGTAGTGTGTCTGGAGCCCGATGACGTGGCCAAGCTCCATGCC
CAGTTGGCCCTAGAAGAGCTGGATGACATCATGAAAAACTTCCTGTTCCCTCCACAGAAGCTGGAGAAGAAGATCATGGTCCTGCCGTAG
ACCTGGCTCCAAGGACGTGGAGGAGGCAGGCAGGGCCAGGCACCCAGAGCCGTGCCCAGGTCTTCCAGCAGGTGGCCCTGCTGCCTCTTG
AGTGCTGGCAGCATGGCTGACCCTCGGGGTGGTTTTATGGTGCAGGTCACTTGGGTCTTCAGGGTCCCTTCCGAGGGCATGTGTTCAGCA
CTCCCGCGTTCAGCCTGAGGGGTGTACAGTTAAGAGAAGACAGTTACAGATCTCATTAATCTACATTTTTCACTGTCCTCTAGCATTGAA
AGAAGGATGTCTACCTGGTGAAAGTATATTTTAACATGACTGATGGAATTTCACTAATTGCCCACTCTCTTGGAACTTGAGGAGAAGCGG
TTGGCCACCCATATGTCACCTAGCTCTATATTCTTTCAGGCTGAGATTCTTCTTCAGGAAAATGAGGAGCAGAACTGGCCACCCTTGGCT
GCTCAAGAGGCATTTCAGAGTAGGAGATGCAGTTGGAGGTGGGGAGGGGAAGGAAATAGTTATCAAATAATGCAAAATGGAATAAAGTTA
TCTTGGATGGAAAGAACAGGGCTAAATCTGGTCCTCTGGTGTCGAGATGGAAAACTGTGGAGTTGAAGAGGCTCTGATGCCCAGAAAGGA
CAATCAAGCTGGTTGACTCTTCCAGAGAAGAAGGGTAAGCCCTGTATTTATCCTCCCAGGCCATTCTTCTTCACTCCTGCTGCTGTTTGC
AGAGAGTTGCCCTGATTATCAGGAGAAAAGAACCACGAGCATCCAGAGAGTTTACATCCTGCCTTCTGTCCTCTGCTCCTTCAGAAAGAT
GAATGCCTAGACAATGGGTTCACACTGAATGCAGGCTGGAAAGAATGCATGCTGGTGGCCTAATGCCAGGGCTGTTGAAACAATTTCAGA
TATAGCACTGTGGTCTCCACTTTATTTCTTTATATGTTTTGGCCGCTGCATTTTGATTGCAGCTAAAAGAGATAACAGAAAGGAGATACT
GGCTGGCTGCTTCATATTAGCCCTCTCTGTTGTCAACACCTTGATGAGGCCAACCCAGAGATGCTTGATCAGTCCTCAGCTTTGCAGGGC
TAGGTACAGAATTTTATCACAGGATTTTATCACGCTCTCTGGGGTGACTAGATCCACAGGAACCAAAACGCAGTTTCCAAAAGCTCGAGT
GACTGAAGGATCTATACACAAACATGGCTATTTGCTAGTTAACAACAGGATATTTCTCTCTGGCCAGATCACAGACATGGTTCTGAGTCA
GATCTTCCTTGGTGGCATCCCTTTAAAGAGGCCATCTTATGAACAGGATCACAAGTGAGCTTAGTGAGCAGAGAGTTAGAACAAATCTAG
CTAGGTGTGTTTAAGGAATATTTCCATTCAGCTAGTGTAGCTGGATTAATTTCTATTCTCCAAATCAAGGATGTCTAGAAAATGGGCATT

>99536_99536_10_WWP2-TANGO6_WWP2_chr16_69922152_ENST00000448661_TANGO6_chr16_68941346_ENST00000261778_length(amino acids)=843AA_BP=305
MASASSSRAGVALPFEKSQLTLKVVSAKPKVHNRQPRINSYVEVAVDGLPSETKKTGKRIGSSELLWNEIIILNVTAQSHLDLKVWSCHT
LRNELLGTASVNLSNVLKNNGGKMENMQLTLNLQTENKGSVVSGGELTIFLDGPTVDLGNVPNGSALTDGSQLPSRDSSGTAVAPENRHQ
PPSTNCFGGRSRTHRHSGASARTTPATGEQSPGARSRHRQPVKNSGHSGLANGTVNDEPTTATDPEEPSVVGVTSPPAAPLSVTPNPNTT
SLPAPATPAEGEEPSTSGTQQLPAAAQAPDALPAGDEDEDEALYQKVSSEQGRVEHLGDLLSHCQECGLAGDFFIFCLKELTHVASENET
ELKTEPFSSKSLLELEQHQTLLVEGQERKLLVLQLMAVLCERMSEQIFTNVTQVVDFVAATLQRACASLAHQAESTVESQTLSMSMGLVA
VMLGGAVQLKSSDFAVLKQLLPLLEKVSNTYPDPVIQELAVDLRITISTHGAFATEAVSMAAQSTLNRKDLEGKIEEQQQTSHERPTDVA
HSHLEQQQSHETAPQTGLQSNAPIIPQGVNEPSTTTSQKSGSVTTEQLQEVLLSAYDPQIPTRAAALRTLSHWIEQREAKALEMQEKLLK
IFLENLEHEDTFVYLSAIQGVALLSDVYPEKILPDLLAQYDSSKDKHTPETRMKVGEVLMRIVRALGDMVSKYREPLIHTFLRGVRDPDG
AHRASSLANLGELCQRLDFLLGSVVHEVTACLIAVAKTDGEVQVRRAAIHVVVLLLRGLSQKATEVLSAVLKDLYHLLKHVVCLEPDDVA

--------------------------------------------------------------
>99536_99536_11_WWP2-TANGO6_WWP2_chr16_69922152_ENST00000542271_TANGO6_chr16_68936231_ENST00000261778_length(transcript)=4041nt_BP=727nt
ATTTTATAGAAACGTTTAGTACTCACCAAGGCCCTCAGTGGAACTGGCTGAAAATAGCAGCAGACTCACTCAGAAAAGAATTGGAGAGAT
CCATGGCAGGGAAGAGAGATTAAGGGAAGGTAGAGCGCTTAGGAGAGCTTGAAAACCCAAAGGTGGAGAACATGCAGCTGACCCTGAACC
TGCAGACGGAGAACAAAGGCAGCGTTGTCTCAGGCGGAGAGCTGACAATTTTCCTGGACGGGCCAACTGTTGATCTGGGAAATGTGCCTA
ATGGCAGTGCCCTGACAGATGGATCACAGCTGCCTTCGAGAGACTCCAGTGGAACAGCAGTAGCTCCAGAGAACCGGCACCAGCCCCCCA
GCACAAACTGCTTTGGTGGAAGATCCCGGACGCACAGACATTCGGGTGCTTCAGCCAGAACAACCCCAGCAACCGGCGAGCAAAGCCCCG
GTGCTCGGAGCCGGCACCGCCAGCCCGTCAAGAACTCAGGCCACAGTGGCTTGGCCAATGGCACAGTGAATGATGAACCCACAACAGCCA
CTGATCCCGAAGAACCTTCCGTTGTTGGTGTGACGTCCCCACCTGCTGCACCCTTGAGTGTGACCCCGAATCCCAACACGACTTCTCTCC
CTGCCCCAGCCACACCGGCTGAAGGAGAGGAACCCAGCACTTCGGGTACACAGCAGCTCCCAGCGGCTGCCCAGGCCCCCGACGCTCTGC
CTGCTGGGTCACTTTGCCAAGAAATCTTATTATGGATTCTGGGGAAGCTGGAAAGGAAGAAGGCAATTGCCAGCCTGAAAGGATTTGCAG
GGTTGGACAAAGCTGTGCCCTCTCTCCATTCTCTGTGTCAGTTTAGAGTTGCCACTCAAGGTGGCATTATGATTACCATCAAAGAGGCCA
TTAGTGATGAAGATGAAGATGAAGCCCTGTACCAGAAGGTATCCTCTGAGCAGGGCCGGGTGGAGCATCTCGGGGACTTGCTGTCCCACT
GCCAGGAATGCGGTTTGGCAGGAGACTTCTTCATCTTCTGTTTGAAAGAGTTGACTCATGTGGCCTCGGAAAATGAAACAGAGTTAAAAA
CTGAGCCCTTCTCCAGCAAGAGCCTCTTGGAATTAGAGCAACATCAGACTCTTCTTGTGGAAGGCCAAGAGCGGAAGCTGCTTGTCCTGC
AGCTGATGGCTGTTCTGTGCGAGAGAATGTCTGAGCAGATATTCACAAACGTCACTCAGGTGGTGGACTTTGTAGCAGCAACATTGCAGA
GAGCCTGTGCAAGCCTGGCCCATCAGGCAGAGAGCACCGTGGAATCACAGACGCTGAGCATGTCCATGGGGCTGGTGGCTGTCATGCTAG
GAGGAGCTGTTCAGTTGAAGTCAAGTGATTTTGCTGTTCTGAAGCAGTTGTTGCCTCTGTTGGAGAAGGTATCCAACACATACCCTGATC
CGGTCATCCAAGAACTCGCTGTTGATCTCCGCATCACCATCTCTACCCATGGAGCCTTTGCCACTGAGGCCGTCAGCATGGCTGCCCAAA
GTACACTGAACAGAAAAGATCTGGAAGGGAAAATAGAAGAGCAGCAACAAACCAGTCATGAAAGACCCACTGATGTAGCTCATAGCCACC
TTGAACAACAGCAGAGCCATGAGACAGCCCCCCAGACAGGCCTGCAGTCAAATGCTCCAATCATTCCTCAAGGAGTCAATGAGCCCAGCA
CTACTACAAGTCAGAAATCTGGAAGCGTAACCACAGAACAGCTCCAAGAGGTTCTTTTGTCAGCTTATGACCCTCAAATTCCAACACGGG
CTGCTGCCCTGCGTACTCTTTCCCACTGGATAGAGCAGAGAGAAGCAAAAGCCCTTGAGATGCAAGAGAAGCTTCTCAAGATATTCTTGG
AAAACTTGGAACATGAAGACACTTTTGTATATCTATCTGCAATTCAGGGGGTTGCCCTGCTGTCAGACGTCTATCCTGAGAAAATCTTGC
CGGACTTGTTGGCTCAATATGACAGCAGCAAAGACAAGCACACACCAGAGACCAGAATGAAAGTCGGGGAAGTCCTTATGCGAATCGTCA
GGGCATTAGGAGACATGGTCTCAAAGTACCGAGAACCTTTGATCCATACCTTCCTGAGGGGAGTGAGAGATCCTGATGGTGCTCACAGGG
CCAGCAGCTTGGCCAACCTTGGGGAGCTGTGCCAGAGGCTGGACTTTCTGCTGGGCTCCGTGGTCCATGAGGTAACAGCTTGCCTGATTG
CTGTGGCCAAAACAGATGGTGAAGTTCAAGTACGCAGAGCTGCCATACATGTGGTTGTGCTGCTGCTTCGGGGACTCAGCCAGAAAGCTA
CTGAGGTGCTGAGCGCCGTCCTCAAGGATCTCTACCACCTGCTGAAGCACGTAGTGTGTCTGGAGCCCGATGACGTGGCCAAGCTCCATG
CCCAGTTGGCCCTAGAAGAGCTGGATGACATCATGAAAAACTTCCTGTTCCCTCCACAGAAGCTGGAGAAGAAGATCATGGTCCTGCCGT
AGACCTGGCTCCAAGGACGTGGAGGAGGCAGGCAGGGCCAGGCACCCAGAGCCGTGCCCAGGTCTTCCAGCAGGTGGCCCTGCTGCCTCT
TGAGTGCTGGCAGCATGGCTGACCCTCGGGGTGGTTTTATGGTGCAGGTCACTTGGGTCTTCAGGGTCCCTTCCGAGGGCATGTGTTCAG
CACTCCCGCGTTCAGCCTGAGGGGTGTACAGTTAAGAGAAGACAGTTACAGATCTCATTAATCTACATTTTTCACTGTCCTCTAGCATTG
AAAGAAGGATGTCTACCTGGTGAAAGTATATTTTAACATGACTGATGGAATTTCACTAATTGCCCACTCTCTTGGAACTTGAGGAGAAGC
GGTTGGCCACCCATATGTCACCTAGCTCTATATTCTTTCAGGCTGAGATTCTTCTTCAGGAAAATGAGGAGCAGAACTGGCCACCCTTGG
CTGCTCAAGAGGCATTTCAGAGTAGGAGATGCAGTTGGAGGTGGGGAGGGGAAGGAAATAGTTATCAAATAATGCAAAATGGAATAAAGT
TATCTTGGATGGAAAGAACAGGGCTAAATCTGGTCCTCTGGTGTCGAGATGGAAAACTGTGGAGTTGAAGAGGCTCTGATGCCCAGAAAG
GACAATCAAGCTGGTTGACTCTTCCAGAGAAGAAGGGTAAGCCCTGTATTTATCCTCCCAGGCCATTCTTCTTCACTCCTGCTGCTGTTT
GCAGAGAGTTGCCCTGATTATCAGGAGAAAAGAACCACGAGCATCCAGAGAGTTTACATCCTGCCTTCTGTCCTCTGCTCCTTCAGAAAG
ATGAATGCCTAGACAATGGGTTCACACTGAATGCAGGCTGGAAAGAATGCATGCTGGTGGCCTAATGCCAGGGCTGTTGAAACAATTTCA
GATATAGCACTGTGGTCTCCACTTTATTTCTTTATATGTTTTGGCCGCTGCATTTTGATTGCAGCTAAAAGAGATAACAGAAAGGAGATA
CTGGCTGGCTGCTTCATATTAGCCCTCTCTGTTGTCAACACCTTGATGAGGCCAACCCAGAGATGCTTGATCAGTCCTCAGCTTTGCAGG
GCTAGGTACAGAATTTTATCACAGGATTTTATCACGCTCTCTGGGGTGACTAGATCCACAGGAACCAAAACGCAGTTTCCAAAAGCTCGA
GTGACTGAAGGATCTATACACAAACATGGCTATTTGCTAGTTAACAACAGGATATTTCTCTCTGGCCAGATCACAGACATGGTTCTGAGT
CAGATCTTCCTTGGTGGCATCCCTTTAAAGAGGCCATCTTATGAACAGGATCACAAGTGAGCTTAGTGAGCAGAGAGTTAGAACAAATCT
AGCTAGGTGTGTTTAAGGAATATTTCCATTCAGCTAGTGTAGCTGGATTAATTTCTATTCTCCAAATCAAGGATGTCTAGAAAATGGGCA

>99536_99536_11_WWP2-TANGO6_WWP2_chr16_69922152_ENST00000542271_TANGO6_chr16_68936231_ENST00000261778_length(amino acids)=786AA_BP=187
MQLTLNLQTENKGSVVSGGELTIFLDGPTVDLGNVPNGSALTDGSQLPSRDSSGTAVAPENRHQPPSTNCFGGRSRTHRHSGASARTTPA
TGEQSPGARSRHRQPVKNSGHSGLANGTVNDEPTTATDPEEPSVVGVTSPPAAPLSVTPNPNTTSLPAPATPAEGEEPSTSGTQQLPAAA
QAPDALPAGSLCQEILLWILGKLERKKAIASLKGFAGLDKAVPSLHSLCQFRVATQGGIMITIKEAISDEDEDEALYQKVSSEQGRVEHL
GDLLSHCQECGLAGDFFIFCLKELTHVASENETELKTEPFSSKSLLELEQHQTLLVEGQERKLLVLQLMAVLCERMSEQIFTNVTQVVDF
VAATLQRACASLAHQAESTVESQTLSMSMGLVAVMLGGAVQLKSSDFAVLKQLLPLLEKVSNTYPDPVIQELAVDLRITISTHGAFATEA
VSMAAQSTLNRKDLEGKIEEQQQTSHERPTDVAHSHLEQQQSHETAPQTGLQSNAPIIPQGVNEPSTTTSQKSGSVTTEQLQEVLLSAYD
PQIPTRAAALRTLSHWIEQREAKALEMQEKLLKIFLENLEHEDTFVYLSAIQGVALLSDVYPEKILPDLLAQYDSSKDKHTPETRMKVGE
VLMRIVRALGDMVSKYREPLIHTFLRGVRDPDGAHRASSLANLGELCQRLDFLLGSVVHEVTACLIAVAKTDGEVQVRRAAIHVVVLLLR

--------------------------------------------------------------
>99536_99536_12_WWP2-TANGO6_WWP2_chr16_69922152_ENST00000542271_TANGO6_chr16_68941346_ENST00000261778_length(transcript)=3864nt_BP=727nt
ATTTTATAGAAACGTTTAGTACTCACCAAGGCCCTCAGTGGAACTGGCTGAAAATAGCAGCAGACTCACTCAGAAAAGAATTGGAGAGAT
CCATGGCAGGGAAGAGAGATTAAGGGAAGGTAGAGCGCTTAGGAGAGCTTGAAAACCCAAAGGTGGAGAACATGCAGCTGACCCTGAACC
TGCAGACGGAGAACAAAGGCAGCGTTGTCTCAGGCGGAGAGCTGACAATTTTCCTGGACGGGCCAACTGTTGATCTGGGAAATGTGCCTA
ATGGCAGTGCCCTGACAGATGGATCACAGCTGCCTTCGAGAGACTCCAGTGGAACAGCAGTAGCTCCAGAGAACCGGCACCAGCCCCCCA
GCACAAACTGCTTTGGTGGAAGATCCCGGACGCACAGACATTCGGGTGCTTCAGCCAGAACAACCCCAGCAACCGGCGAGCAAAGCCCCG
GTGCTCGGAGCCGGCACCGCCAGCCCGTCAAGAACTCAGGCCACAGTGGCTTGGCCAATGGCACAGTGAATGATGAACCCACAACAGCCA
CTGATCCCGAAGAACCTTCCGTTGTTGGTGTGACGTCCCCACCTGCTGCACCCTTGAGTGTGACCCCGAATCCCAACACGACTTCTCTCC
CTGCCCCAGCCACACCGGCTGAAGGAGAGGAACCCAGCACTTCGGGTACACAGCAGCTCCCAGCGGCTGCCCAGGCCCCCGACGCTCTGC
CTGCTGGTGATGAAGATGAAGATGAAGCCCTGTACCAGAAGGTATCCTCTGAGCAGGGCCGGGTGGAGCATCTCGGGGACTTGCTGTCCC
ACTGCCAGGAATGCGGTTTGGCAGGAGACTTCTTCATCTTCTGTTTGAAAGAGTTGACTCATGTGGCCTCGGAAAATGAAACAGAGTTAA
AAACTGAGCCCTTCTCCAGCAAGAGCCTCTTGGAATTAGAGCAACATCAGACTCTTCTTGTGGAAGGCCAAGAGCGGAAGCTGCTTGTCC
TGCAGCTGATGGCTGTTCTGTGCGAGAGAATGTCTGAGCAGATATTCACAAACGTCACTCAGGTGGTGGACTTTGTAGCAGCAACATTGC
AGAGAGCCTGTGCAAGCCTGGCCCATCAGGCAGAGAGCACCGTGGAATCACAGACGCTGAGCATGTCCATGGGGCTGGTGGCTGTCATGC
TAGGAGGAGCTGTTCAGTTGAAGTCAAGTGATTTTGCTGTTCTGAAGCAGTTGTTGCCTCTGTTGGAGAAGGTATCCAACACATACCCTG
ATCCGGTCATCCAAGAACTCGCTGTTGATCTCCGCATCACCATCTCTACCCATGGAGCCTTTGCCACTGAGGCCGTCAGCATGGCTGCCC
AAAGTACACTGAACAGAAAAGATCTGGAAGGGAAAATAGAAGAGCAGCAACAAACCAGTCATGAAAGACCCACTGATGTAGCTCATAGCC
ACCTTGAACAACAGCAGAGCCATGAGACAGCCCCCCAGACAGGCCTGCAGTCAAATGCTCCAATCATTCCTCAAGGAGTCAATGAGCCCA
GCACTACTACAAGTCAGAAATCTGGAAGCGTAACCACAGAACAGCTCCAAGAGGTTCTTTTGTCAGCTTATGACCCTCAAATTCCAACAC
GGGCTGCTGCCCTGCGTACTCTTTCCCACTGGATAGAGCAGAGAGAAGCAAAAGCCCTTGAGATGCAAGAGAAGCTTCTCAAGATATTCT
TGGAAAACTTGGAACATGAAGACACTTTTGTATATCTATCTGCAATTCAGGGGGTTGCCCTGCTGTCAGACGTCTATCCTGAGAAAATCT
TGCCGGACTTGTTGGCTCAATATGACAGCAGCAAAGACAAGCACACACCAGAGACCAGAATGAAAGTCGGGGAAGTCCTTATGCGAATCG
TCAGGGCATTAGGAGACATGGTCTCAAAGTACCGAGAACCTTTGATCCATACCTTCCTGAGGGGAGTGAGAGATCCTGATGGTGCTCACA
GGGCCAGCAGCTTGGCCAACCTTGGGGAGCTGTGCCAGAGGCTGGACTTTCTGCTGGGCTCCGTGGTCCATGAGGTAACAGCTTGCCTGA
TTGCTGTGGCCAAAACAGATGGTGAAGTTCAAGTACGCAGAGCTGCCATACATGTGGTTGTGCTGCTGCTTCGGGGACTCAGCCAGAAAG
CTACTGAGGTGCTGAGCGCCGTCCTCAAGGATCTCTACCACCTGCTGAAGCACGTAGTGTGTCTGGAGCCCGATGACGTGGCCAAGCTCC
ATGCCCAGTTGGCCCTAGAAGAGCTGGATGACATCATGAAAAACTTCCTGTTCCCTCCACAGAAGCTGGAGAAGAAGATCATGGTCCTGC
CGTAGACCTGGCTCCAAGGACGTGGAGGAGGCAGGCAGGGCCAGGCACCCAGAGCCGTGCCCAGGTCTTCCAGCAGGTGGCCCTGCTGCC
TCTTGAGTGCTGGCAGCATGGCTGACCCTCGGGGTGGTTTTATGGTGCAGGTCACTTGGGTCTTCAGGGTCCCTTCCGAGGGCATGTGTT
CAGCACTCCCGCGTTCAGCCTGAGGGGTGTACAGTTAAGAGAAGACAGTTACAGATCTCATTAATCTACATTTTTCACTGTCCTCTAGCA
TTGAAAGAAGGATGTCTACCTGGTGAAAGTATATTTTAACATGACTGATGGAATTTCACTAATTGCCCACTCTCTTGGAACTTGAGGAGA
AGCGGTTGGCCACCCATATGTCACCTAGCTCTATATTCTTTCAGGCTGAGATTCTTCTTCAGGAAAATGAGGAGCAGAACTGGCCACCCT
TGGCTGCTCAAGAGGCATTTCAGAGTAGGAGATGCAGTTGGAGGTGGGGAGGGGAAGGAAATAGTTATCAAATAATGCAAAATGGAATAA
AGTTATCTTGGATGGAAAGAACAGGGCTAAATCTGGTCCTCTGGTGTCGAGATGGAAAACTGTGGAGTTGAAGAGGCTCTGATGCCCAGA
AAGGACAATCAAGCTGGTTGACTCTTCCAGAGAAGAAGGGTAAGCCCTGTATTTATCCTCCCAGGCCATTCTTCTTCACTCCTGCTGCTG
TTTGCAGAGAGTTGCCCTGATTATCAGGAGAAAAGAACCACGAGCATCCAGAGAGTTTACATCCTGCCTTCTGTCCTCTGCTCCTTCAGA
AAGATGAATGCCTAGACAATGGGTTCACACTGAATGCAGGCTGGAAAGAATGCATGCTGGTGGCCTAATGCCAGGGCTGTTGAAACAATT
TCAGATATAGCACTGTGGTCTCCACTTTATTTCTTTATATGTTTTGGCCGCTGCATTTTGATTGCAGCTAAAAGAGATAACAGAAAGGAG
ATACTGGCTGGCTGCTTCATATTAGCCCTCTCTGTTGTCAACACCTTGATGAGGCCAACCCAGAGATGCTTGATCAGTCCTCAGCTTTGC
AGGGCTAGGTACAGAATTTTATCACAGGATTTTATCACGCTCTCTGGGGTGACTAGATCCACAGGAACCAAAACGCAGTTTCCAAAAGCT
CGAGTGACTGAAGGATCTATACACAAACATGGCTATTTGCTAGTTAACAACAGGATATTTCTCTCTGGCCAGATCACAGACATGGTTCTG
AGTCAGATCTTCCTTGGTGGCATCCCTTTAAAGAGGCCATCTTATGAACAGGATCACAAGTGAGCTTAGTGAGCAGAGAGTTAGAACAAA
TCTAGCTAGGTGTGTTTAAGGAATATTTCCATTCAGCTAGTGTAGCTGGATTAATTTCTATTCTCCAAATCAAGGATGTCTAGAAAATGG

>99536_99536_12_WWP2-TANGO6_WWP2_chr16_69922152_ENST00000542271_TANGO6_chr16_68941346_ENST00000261778_length(amino acids)=727AA_BP=189
MQLTLNLQTENKGSVVSGGELTIFLDGPTVDLGNVPNGSALTDGSQLPSRDSSGTAVAPENRHQPPSTNCFGGRSRTHRHSGASARTTPA
TGEQSPGARSRHRQPVKNSGHSGLANGTVNDEPTTATDPEEPSVVGVTSPPAAPLSVTPNPNTTSLPAPATPAEGEEPSTSGTQQLPAAA
QAPDALPAGDEDEDEALYQKVSSEQGRVEHLGDLLSHCQECGLAGDFFIFCLKELTHVASENETELKTEPFSSKSLLELEQHQTLLVEGQ
ERKLLVLQLMAVLCERMSEQIFTNVTQVVDFVAATLQRACASLAHQAESTVESQTLSMSMGLVAVMLGGAVQLKSSDFAVLKQLLPLLEK
VSNTYPDPVIQELAVDLRITISTHGAFATEAVSMAAQSTLNRKDLEGKIEEQQQTSHERPTDVAHSHLEQQQSHETAPQTGLQSNAPIIP
QGVNEPSTTTSQKSGSVTTEQLQEVLLSAYDPQIPTRAAALRTLSHWIEQREAKALEMQEKLLKIFLENLEHEDTFVYLSAIQGVALLSD
VYPEKILPDLLAQYDSSKDKHTPETRMKVGEVLMRIVRALGDMVSKYREPLIHTFLRGVRDPDGAHRASSLANLGELCQRLDFLLGSVVH
EVTACLIAVAKTDGEVQVRRAAIHVVVLLLRGLSQKATEVLSAVLKDLYHLLKHVVCLEPDDVAKLHAQLALEELDDIMKNFLFPPQKLE

--------------------------------------------------------------
>99536_99536_13_WWP2-TANGO6_WWP2_chr16_69922152_ENST00000569174_TANGO6_chr16_68936231_ENST00000261778_length(transcript)=4298nt_BP=984nt
AGATGAAACAGAAAGGCTAAAGAGGGCTGGAGTCAGGGGACTTCTCTTCCACCAGCTTCACGGTGATGATATGGCATCTGCCAGCTCTAG
CCGGGCAGGAGTGGCCCTGCCTTTTGAGAAGTCTCAGCTCACTTTGAAAGTGGTGTCCGCAAAGCCCAAGGTGCATAATCGTCAACCTCG
AATTAACTCCTACGTGGAGGTGGCGGTGGATGGACTCCCCAGTGAGACCAAGAAGACTGGGAAGCGCATTGGGAGCTCTGAGCTTCTCTG
GAATGAGATCATCATTTTGAATGTCACGGCACAGAGTCATTTAGATTTAAAGGTCTGGAGCTGCCATACCTTGAGAAATGAACTGCTAGG
CACCGCATCTGTCAACCTCTCCAACGTCTTGAAGAACAATGGGGGCAAAATGGAGAACATGCAGCTGACCCTGAACCTGCAGACGGAGAA
CAAAGGCAGCGTTGTCTCAGGCGGAGAGCTGACAATTTTCCTGGACGGGCCAACTGTTGATCTGGGAAATGTGCCTAATGGCAGTGCCCT
GACAGATGGATCACAGCTGCCTTCGAGAGACTCCAGTGGAACAGCAGTAGCTCCAGAGAACCGGCACCAGCCCCCCAGCACAAACTGCTT
TGGTGGAAGATCCCGGACGCACAGACATTCGGGTGCTTCAGCCAGAACAACCCCAGCAACCGGCGAGCAAAGCCCCGGTGCTCGGAGCCG
GCACCGCCAGCCCGTCAAGAACTCAGGCCACAGTGGCTTGGCCAATGGCACAGTGAATGATGAACCCACAACAGCCACTGATCCCGAAGA
ACCTTCCGTTGTTGGTGTGACGTCCCCACCTGCTGCACCCTTGAGTGTGACCCCGAATCCCAACACGACTTCTCTCCCTGCCCCAGCCAC
ACCGGCTGAAGGAGAGGAACCCAGCACTTCGGGTACACAGCAGCTCCCAGCGGCTGCCCAGGCCCCCGACGCTCTGCCTGCTGGGTCACT
TTGCCAAGAAATCTTATTATGGATTCTGGGGAAGCTGGAAAGGAAGAAGGCAATTGCCAGCCTGAAAGGATTTGCAGGGTTGGACAAAGC
TGTGCCCTCTCTCCATTCTCTGTGTCAGTTTAGAGTTGCCACTCAAGGTGGCATTATGATTACCATCAAAGAGGCCATTAGTGATGAAGA
TGAAGATGAAGCCCTGTACCAGAAGGTATCCTCTGAGCAGGGCCGGGTGGAGCATCTCGGGGACTTGCTGTCCCACTGCCAGGAATGCGG
TTTGGCAGGAGACTTCTTCATCTTCTGTTTGAAAGAGTTGACTCATGTGGCCTCGGAAAATGAAACAGAGTTAAAAACTGAGCCCTTCTC
CAGCAAGAGCCTCTTGGAATTAGAGCAACATCAGACTCTTCTTGTGGAAGGCCAAGAGCGGAAGCTGCTTGTCCTGCAGCTGATGGCTGT
TCTGTGCGAGAGAATGTCTGAGCAGATATTCACAAACGTCACTCAGGTGGTGGACTTTGTAGCAGCAACATTGCAGAGAGCCTGTGCAAG
CCTGGCCCATCAGGCAGAGAGCACCGTGGAATCACAGACGCTGAGCATGTCCATGGGGCTGGTGGCTGTCATGCTAGGAGGAGCTGTTCA
GTTGAAGTCAAGTGATTTTGCTGTTCTGAAGCAGTTGTTGCCTCTGTTGGAGAAGGTATCCAACACATACCCTGATCCGGTCATCCAAGA
ACTCGCTGTTGATCTCCGCATCACCATCTCTACCCATGGAGCCTTTGCCACTGAGGCCGTCAGCATGGCTGCCCAAAGTACACTGAACAG
AAAAGATCTGGAAGGGAAAATAGAAGAGCAGCAACAAACCAGTCATGAAAGACCCACTGATGTAGCTCATAGCCACCTTGAACAACAGCA
GAGCCATGAGACAGCCCCCCAGACAGGCCTGCAGTCAAATGCTCCAATCATTCCTCAAGGAGTCAATGAGCCCAGCACTACTACAAGTCA
GAAATCTGGAAGCGTAACCACAGAACAGCTCCAAGAGGTTCTTTTGTCAGCTTATGACCCTCAAATTCCAACACGGGCTGCTGCCCTGCG
TACTCTTTCCCACTGGATAGAGCAGAGAGAAGCAAAAGCCCTTGAGATGCAAGAGAAGCTTCTCAAGATATTCTTGGAAAACTTGGAACA
TGAAGACACTTTTGTATATCTATCTGCAATTCAGGGGGTTGCCCTGCTGTCAGACGTCTATCCTGAGAAAATCTTGCCGGACTTGTTGGC
TCAATATGACAGCAGCAAAGACAAGCACACACCAGAGACCAGAATGAAAGTCGGGGAAGTCCTTATGCGAATCGTCAGGGCATTAGGAGA
CATGGTCTCAAAGTACCGAGAACCTTTGATCCATACCTTCCTGAGGGGAGTGAGAGATCCTGATGGTGCTCACAGGGCCAGCAGCTTGGC
CAACCTTGGGGAGCTGTGCCAGAGGCTGGACTTTCTGCTGGGCTCCGTGGTCCATGAGGTAACAGCTTGCCTGATTGCTGTGGCCAAAAC
AGATGGTGAAGTTCAAGTACGCAGAGCTGCCATACATGTGGTTGTGCTGCTGCTTCGGGGACTCAGCCAGAAAGCTACTGAGGTGCTGAG
CGCCGTCCTCAAGGATCTCTACCACCTGCTGAAGCACGTAGTGTGTCTGGAGCCCGATGACGTGGCCAAGCTCCATGCCCAGTTGGCCCT
AGAAGAGCTGGATGACATCATGAAAAACTTCCTGTTCCCTCCACAGAAGCTGGAGAAGAAGATCATGGTCCTGCCGTAGACCTGGCTCCA
AGGACGTGGAGGAGGCAGGCAGGGCCAGGCACCCAGAGCCGTGCCCAGGTCTTCCAGCAGGTGGCCCTGCTGCCTCTTGAGTGCTGGCAG
CATGGCTGACCCTCGGGGTGGTTTTATGGTGCAGGTCACTTGGGTCTTCAGGGTCCCTTCCGAGGGCATGTGTTCAGCACTCCCGCGTTC
AGCCTGAGGGGTGTACAGTTAAGAGAAGACAGTTACAGATCTCATTAATCTACATTTTTCACTGTCCTCTAGCATTGAAAGAAGGATGTC
TACCTGGTGAAAGTATATTTTAACATGACTGATGGAATTTCACTAATTGCCCACTCTCTTGGAACTTGAGGAGAAGCGGTTGGCCACCCA
TATGTCACCTAGCTCTATATTCTTTCAGGCTGAGATTCTTCTTCAGGAAAATGAGGAGCAGAACTGGCCACCCTTGGCTGCTCAAGAGGC
ATTTCAGAGTAGGAGATGCAGTTGGAGGTGGGGAGGGGAAGGAAATAGTTATCAAATAATGCAAAATGGAATAAAGTTATCTTGGATGGA
AAGAACAGGGCTAAATCTGGTCCTCTGGTGTCGAGATGGAAAACTGTGGAGTTGAAGAGGCTCTGATGCCCAGAAAGGACAATCAAGCTG
GTTGACTCTTCCAGAGAAGAAGGGTAAGCCCTGTATTTATCCTCCCAGGCCATTCTTCTTCACTCCTGCTGCTGTTTGCAGAGAGTTGCC
CTGATTATCAGGAGAAAAGAACCACGAGCATCCAGAGAGTTTACATCCTGCCTTCTGTCCTCTGCTCCTTCAGAAAGATGAATGCCTAGA
CAATGGGTTCACACTGAATGCAGGCTGGAAAGAATGCATGCTGGTGGCCTAATGCCAGGGCTGTTGAAACAATTTCAGATATAGCACTGT
GGTCTCCACTTTATTTCTTTATATGTTTTGGCCGCTGCATTTTGATTGCAGCTAAAAGAGATAACAGAAAGGAGATACTGGCTGGCTGCT
TCATATTAGCCCTCTCTGTTGTCAACACCTTGATGAGGCCAACCCAGAGATGCTTGATCAGTCCTCAGCTTTGCAGGGCTAGGTACAGAA
TTTTATCACAGGATTTTATCACGCTCTCTGGGGTGACTAGATCCACAGGAACCAAAACGCAGTTTCCAAAAGCTCGAGTGACTGAAGGAT
CTATACACAAACATGGCTATTTGCTAGTTAACAACAGGATATTTCTCTCTGGCCAGATCACAGACATGGTTCTGAGTCAGATCTTCCTTG
GTGGCATCCCTTTAAAGAGGCCATCTTATGAACAGGATCACAAGTGAGCTTAGTGAGCAGAGAGTTAGAACAAATCTAGCTAGGTGTGTT
TAAGGAATATTTCCATTCAGCTAGTGTAGCTGGATTAATTTCTATTCTCCAAATCAAGGATGTCTAGAAAATGGGCATTGTGGCTTTCAA

>99536_99536_13_WWP2-TANGO6_WWP2_chr16_69922152_ENST00000569174_TANGO6_chr16_68936231_ENST00000261778_length(amino acids)=902AA_BP=303
MASASSSRAGVALPFEKSQLTLKVVSAKPKVHNRQPRINSYVEVAVDGLPSETKKTGKRIGSSELLWNEIIILNVTAQSHLDLKVWSCHT
LRNELLGTASVNLSNVLKNNGGKMENMQLTLNLQTENKGSVVSGGELTIFLDGPTVDLGNVPNGSALTDGSQLPSRDSSGTAVAPENRHQ
PPSTNCFGGRSRTHRHSGASARTTPATGEQSPGARSRHRQPVKNSGHSGLANGTVNDEPTTATDPEEPSVVGVTSPPAAPLSVTPNPNTT
SLPAPATPAEGEEPSTSGTQQLPAAAQAPDALPAGSLCQEILLWILGKLERKKAIASLKGFAGLDKAVPSLHSLCQFRVATQGGIMITIK
EAISDEDEDEALYQKVSSEQGRVEHLGDLLSHCQECGLAGDFFIFCLKELTHVASENETELKTEPFSSKSLLELEQHQTLLVEGQERKLL
VLQLMAVLCERMSEQIFTNVTQVVDFVAATLQRACASLAHQAESTVESQTLSMSMGLVAVMLGGAVQLKSSDFAVLKQLLPLLEKVSNTY
PDPVIQELAVDLRITISTHGAFATEAVSMAAQSTLNRKDLEGKIEEQQQTSHERPTDVAHSHLEQQQSHETAPQTGLQSNAPIIPQGVNE
PSTTTSQKSGSVTTEQLQEVLLSAYDPQIPTRAAALRTLSHWIEQREAKALEMQEKLLKIFLENLEHEDTFVYLSAIQGVALLSDVYPEK
ILPDLLAQYDSSKDKHTPETRMKVGEVLMRIVRALGDMVSKYREPLIHTFLRGVRDPDGAHRASSLANLGELCQRLDFLLGSVVHEVTAC
LIAVAKTDGEVQVRRAAIHVVVLLLRGLSQKATEVLSAVLKDLYHLLKHVVCLEPDDVAKLHAQLALEELDDIMKNFLFPPQKLEKKIMV

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>99536_99536_14_WWP2-TANGO6_WWP2_chr16_69922152_ENST00000569174_TANGO6_chr16_68941346_ENST00000261778_length(transcript)=4121nt_BP=984nt
AGATGAAACAGAAAGGCTAAAGAGGGCTGGAGTCAGGGGACTTCTCTTCCACCAGCTTCACGGTGATGATATGGCATCTGCCAGCTCTAG
CCGGGCAGGAGTGGCCCTGCCTTTTGAGAAGTCTCAGCTCACTTTGAAAGTGGTGTCCGCAAAGCCCAAGGTGCATAATCGTCAACCTCG
AATTAACTCCTACGTGGAGGTGGCGGTGGATGGACTCCCCAGTGAGACCAAGAAGACTGGGAAGCGCATTGGGAGCTCTGAGCTTCTCTG
GAATGAGATCATCATTTTGAATGTCACGGCACAGAGTCATTTAGATTTAAAGGTCTGGAGCTGCCATACCTTGAGAAATGAACTGCTAGG
CACCGCATCTGTCAACCTCTCCAACGTCTTGAAGAACAATGGGGGCAAAATGGAGAACATGCAGCTGACCCTGAACCTGCAGACGGAGAA
CAAAGGCAGCGTTGTCTCAGGCGGAGAGCTGACAATTTTCCTGGACGGGCCAACTGTTGATCTGGGAAATGTGCCTAATGGCAGTGCCCT
GACAGATGGATCACAGCTGCCTTCGAGAGACTCCAGTGGAACAGCAGTAGCTCCAGAGAACCGGCACCAGCCCCCCAGCACAAACTGCTT
TGGTGGAAGATCCCGGACGCACAGACATTCGGGTGCTTCAGCCAGAACAACCCCAGCAACCGGCGAGCAAAGCCCCGGTGCTCGGAGCCG
GCACCGCCAGCCCGTCAAGAACTCAGGCCACAGTGGCTTGGCCAATGGCACAGTGAATGATGAACCCACAACAGCCACTGATCCCGAAGA
ACCTTCCGTTGTTGGTGTGACGTCCCCACCTGCTGCACCCTTGAGTGTGACCCCGAATCCCAACACGACTTCTCTCCCTGCCCCAGCCAC
ACCGGCTGAAGGAGAGGAACCCAGCACTTCGGGTACACAGCAGCTCCCAGCGGCTGCCCAGGCCCCCGACGCTCTGCCTGCTGGTGATGA
AGATGAAGATGAAGCCCTGTACCAGAAGGTATCCTCTGAGCAGGGCCGGGTGGAGCATCTCGGGGACTTGCTGTCCCACTGCCAGGAATG
CGGTTTGGCAGGAGACTTCTTCATCTTCTGTTTGAAAGAGTTGACTCATGTGGCCTCGGAAAATGAAACAGAGTTAAAAACTGAGCCCTT
CTCCAGCAAGAGCCTCTTGGAATTAGAGCAACATCAGACTCTTCTTGTGGAAGGCCAAGAGCGGAAGCTGCTTGTCCTGCAGCTGATGGC
TGTTCTGTGCGAGAGAATGTCTGAGCAGATATTCACAAACGTCACTCAGGTGGTGGACTTTGTAGCAGCAACATTGCAGAGAGCCTGTGC
AAGCCTGGCCCATCAGGCAGAGAGCACCGTGGAATCACAGACGCTGAGCATGTCCATGGGGCTGGTGGCTGTCATGCTAGGAGGAGCTGT
TCAGTTGAAGTCAAGTGATTTTGCTGTTCTGAAGCAGTTGTTGCCTCTGTTGGAGAAGGTATCCAACACATACCCTGATCCGGTCATCCA
AGAACTCGCTGTTGATCTCCGCATCACCATCTCTACCCATGGAGCCTTTGCCACTGAGGCCGTCAGCATGGCTGCCCAAAGTACACTGAA
CAGAAAAGATCTGGAAGGGAAAATAGAAGAGCAGCAACAAACCAGTCATGAAAGACCCACTGATGTAGCTCATAGCCACCTTGAACAACA
GCAGAGCCATGAGACAGCCCCCCAGACAGGCCTGCAGTCAAATGCTCCAATCATTCCTCAAGGAGTCAATGAGCCCAGCACTACTACAAG
TCAGAAATCTGGAAGCGTAACCACAGAACAGCTCCAAGAGGTTCTTTTGTCAGCTTATGACCCTCAAATTCCAACACGGGCTGCTGCCCT
GCGTACTCTTTCCCACTGGATAGAGCAGAGAGAAGCAAAAGCCCTTGAGATGCAAGAGAAGCTTCTCAAGATATTCTTGGAAAACTTGGA
ACATGAAGACACTTTTGTATATCTATCTGCAATTCAGGGGGTTGCCCTGCTGTCAGACGTCTATCCTGAGAAAATCTTGCCGGACTTGTT
GGCTCAATATGACAGCAGCAAAGACAAGCACACACCAGAGACCAGAATGAAAGTCGGGGAAGTCCTTATGCGAATCGTCAGGGCATTAGG
AGACATGGTCTCAAAGTACCGAGAACCTTTGATCCATACCTTCCTGAGGGGAGTGAGAGATCCTGATGGTGCTCACAGGGCCAGCAGCTT
GGCCAACCTTGGGGAGCTGTGCCAGAGGCTGGACTTTCTGCTGGGCTCCGTGGTCCATGAGGTAACAGCTTGCCTGATTGCTGTGGCCAA
AACAGATGGTGAAGTTCAAGTACGCAGAGCTGCCATACATGTGGTTGTGCTGCTGCTTCGGGGACTCAGCCAGAAAGCTACTGAGGTGCT
GAGCGCCGTCCTCAAGGATCTCTACCACCTGCTGAAGCACGTAGTGTGTCTGGAGCCCGATGACGTGGCCAAGCTCCATGCCCAGTTGGC
CCTAGAAGAGCTGGATGACATCATGAAAAACTTCCTGTTCCCTCCACAGAAGCTGGAGAAGAAGATCATGGTCCTGCCGTAGACCTGGCT
CCAAGGACGTGGAGGAGGCAGGCAGGGCCAGGCACCCAGAGCCGTGCCCAGGTCTTCCAGCAGGTGGCCCTGCTGCCTCTTGAGTGCTGG
CAGCATGGCTGACCCTCGGGGTGGTTTTATGGTGCAGGTCACTTGGGTCTTCAGGGTCCCTTCCGAGGGCATGTGTTCAGCACTCCCGCG
TTCAGCCTGAGGGGTGTACAGTTAAGAGAAGACAGTTACAGATCTCATTAATCTACATTTTTCACTGTCCTCTAGCATTGAAAGAAGGAT
GTCTACCTGGTGAAAGTATATTTTAACATGACTGATGGAATTTCACTAATTGCCCACTCTCTTGGAACTTGAGGAGAAGCGGTTGGCCAC
CCATATGTCACCTAGCTCTATATTCTTTCAGGCTGAGATTCTTCTTCAGGAAAATGAGGAGCAGAACTGGCCACCCTTGGCTGCTCAAGA
GGCATTTCAGAGTAGGAGATGCAGTTGGAGGTGGGGAGGGGAAGGAAATAGTTATCAAATAATGCAAAATGGAATAAAGTTATCTTGGAT
GGAAAGAACAGGGCTAAATCTGGTCCTCTGGTGTCGAGATGGAAAACTGTGGAGTTGAAGAGGCTCTGATGCCCAGAAAGGACAATCAAG
CTGGTTGACTCTTCCAGAGAAGAAGGGTAAGCCCTGTATTTATCCTCCCAGGCCATTCTTCTTCACTCCTGCTGCTGTTTGCAGAGAGTT
GCCCTGATTATCAGGAGAAAAGAACCACGAGCATCCAGAGAGTTTACATCCTGCCTTCTGTCCTCTGCTCCTTCAGAAAGATGAATGCCT
AGACAATGGGTTCACACTGAATGCAGGCTGGAAAGAATGCATGCTGGTGGCCTAATGCCAGGGCTGTTGAAACAATTTCAGATATAGCAC
TGTGGTCTCCACTTTATTTCTTTATATGTTTTGGCCGCTGCATTTTGATTGCAGCTAAAAGAGATAACAGAAAGGAGATACTGGCTGGCT
GCTTCATATTAGCCCTCTCTGTTGTCAACACCTTGATGAGGCCAACCCAGAGATGCTTGATCAGTCCTCAGCTTTGCAGGGCTAGGTACA
GAATTTTATCACAGGATTTTATCACGCTCTCTGGGGTGACTAGATCCACAGGAACCAAAACGCAGTTTCCAAAAGCTCGAGTGACTGAAG
GATCTATACACAAACATGGCTATTTGCTAGTTAACAACAGGATATTTCTCTCTGGCCAGATCACAGACATGGTTCTGAGTCAGATCTTCC
TTGGTGGCATCCCTTTAAAGAGGCCATCTTATGAACAGGATCACAAGTGAGCTTAGTGAGCAGAGAGTTAGAACAAATCTAGCTAGGTGT
GTTTAAGGAATATTTCCATTCAGCTAGTGTAGCTGGATTAATTTCTATTCTCCAAATCAAGGATGTCTAGAAAATGGGCATTGTGGCTTT

>99536_99536_14_WWP2-TANGO6_WWP2_chr16_69922152_ENST00000569174_TANGO6_chr16_68941346_ENST00000261778_length(amino acids)=843AA_BP=305
MASASSSRAGVALPFEKSQLTLKVVSAKPKVHNRQPRINSYVEVAVDGLPSETKKTGKRIGSSELLWNEIIILNVTAQSHLDLKVWSCHT
LRNELLGTASVNLSNVLKNNGGKMENMQLTLNLQTENKGSVVSGGELTIFLDGPTVDLGNVPNGSALTDGSQLPSRDSSGTAVAPENRHQ
PPSTNCFGGRSRTHRHSGASARTTPATGEQSPGARSRHRQPVKNSGHSGLANGTVNDEPTTATDPEEPSVVGVTSPPAAPLSVTPNPNTT
SLPAPATPAEGEEPSTSGTQQLPAAAQAPDALPAGDEDEDEALYQKVSSEQGRVEHLGDLLSHCQECGLAGDFFIFCLKELTHVASENET
ELKTEPFSSKSLLELEQHQTLLVEGQERKLLVLQLMAVLCERMSEQIFTNVTQVVDFVAATLQRACASLAHQAESTVESQTLSMSMGLVA
VMLGGAVQLKSSDFAVLKQLLPLLEKVSNTYPDPVIQELAVDLRITISTHGAFATEAVSMAAQSTLNRKDLEGKIEEQQQTSHERPTDVA
HSHLEQQQSHETAPQTGLQSNAPIIPQGVNEPSTTTSQKSGSVTTEQLQEVLLSAYDPQIPTRAAALRTLSHWIEQREAKALEMQEKLLK
IFLENLEHEDTFVYLSAIQGVALLSDVYPEKILPDLLAQYDSSKDKHTPETRMKVGEVLMRIVRALGDMVSKYREPLIHTFLRGVRDPDG
AHRASSLANLGELCQRLDFLLGSVVHEVTACLIAVAKTDGEVQVRRAAIHVVVLLLRGLSQKATEVLSAVLKDLYHLLKHVVCLEPDDVA

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Fusion Gene PPI Analysis for WWP2-TANGO6


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for WWP2-TANGO6


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for WWP2-TANGO6


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource