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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:XPO5-SCAP (FusionGDB2 ID:99682)

Fusion Gene Summary for XPO5-SCAP

check button Fusion gene summary
Fusion gene informationFusion gene name: XPO5-SCAP
Fusion gene ID: 99682
HgeneTgene
Gene symbol

XPO5

SCAP

Gene ID

57510

22937

Gene nameexportin 5SREBF chaperone
Synonymsexp5-
Cytomap

6p21.1

3p21.31

Type of geneprotein-codingprotein-coding
Descriptionexportin-5ran-binding protein 21sterol regulatory element-binding protein cleavage-activating proteinSREBP cleavage-activating protein
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000265351, ENST00000424378, 
ENST00000545718, ENST00000465628, 
ENST00000265565, ENST00000441517, 
Fusion gene scores* DoF score9 X 11 X 6=5949 X 7 X 3=189
# samples 1010
** MAII scorelog2(10/594*10)=-2.57046293102604
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(10/189*10)=-0.918386234446348
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: XPO5 [Title/Abstract] AND SCAP [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointXPO5(43501644)-SCAP(47464026), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneXPO5

GO:0006611

protein export from nucleus

11777942|24209753

HgeneXPO5

GO:0035281

pre-miRNA export from nucleus

15613540

HgeneXPO5

GO:1900370

positive regulation of RNA interference

15613540


check buttonFusion gene breakpoints across XPO5 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across SCAP (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4KIRCTCGA-CJ-4868-01AXPO5chr6

43501644

-SCAPchr3

47464026

-


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Fusion Gene ORF analysis for XPO5-SCAP

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000265351ENST00000545718XPO5chr6

43501644

-SCAPchr3

47464026

-
5CDS-intronENST00000265351ENST00000465628XPO5chr6

43501644

-SCAPchr3

47464026

-
In-frameENST00000265351ENST00000265565XPO5chr6

43501644

-SCAPchr3

47464026

-
In-frameENST00000265351ENST00000441517XPO5chr6

43501644

-SCAPchr3

47464026

-
intron-3CDSENST00000424378ENST00000265565XPO5chr6

43501644

-SCAPchr3

47464026

-
intron-3CDSENST00000424378ENST00000441517XPO5chr6

43501644

-SCAPchr3

47464026

-
intron-5UTRENST00000424378ENST00000545718XPO5chr6

43501644

-SCAPchr3

47464026

-
intron-intronENST00000424378ENST00000465628XPO5chr6

43501644

-SCAPchr3

47464026

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000265351XPO5chr643501644-ENST00000265565SCAPchr347464026-5485265421153431710
ENST00000265351XPO5chr643501644-ENST00000441517SCAPchr347464026-5474265421153401709

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000265351ENST00000265565XPO5chr643501644-SCAPchr347464026-0.0011440840.99885595
ENST00000265351ENST00000441517XPO5chr643501644-SCAPchr347464026-0.001296480.9987035

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Fusion Genomic Features for XPO5-SCAP


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for XPO5-SCAP


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr6:43501644/chr3:47464026)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneXPO5chr6:43501644chr3:47464026ENST00000265351-2132641_6428141205.0RegionPre-miRNA binding
TgeneSCAPchr6:43501644chr3:47464026ENST00000265565823722_7293831280.0Compositional biasNote=Poly-Leu
TgeneSCAPchr6:43501644chr3:47464026ENST00000265565823747_7503831280.0Compositional biasNote=Poly-Arg
TgeneSCAPchr6:43501644chr3:47464026ENST00000265565823861_8643831280.0Compositional biasNote=Poly-Pro
TgeneSCAPchr6:43501644chr3:47464026ENST00000545718318722_7290887.0Compositional biasNote=Poly-Leu
TgeneSCAPchr6:43501644chr3:47464026ENST00000545718318747_7500887.0Compositional biasNote=Poly-Arg
TgeneSCAPchr6:43501644chr3:47464026ENST00000545718318861_8640887.0Compositional biasNote=Poly-Pro
TgeneSCAPchr6:43501644chr3:47464026ENST00000545718318284_4420887.0DomainSSD
TgeneSCAPchr6:43501644chr3:47464026ENST00000265565823447_4523831280.0MotifER export signal
TgeneSCAPchr6:43501644chr3:47464026ENST00000545718318447_4520887.0MotifER export signal
TgeneSCAPchr6:43501644chr3:47464026ENST00000265565823535_7103831280.0RegionLoop-7
TgeneSCAPchr6:43501644chr3:47464026ENST0000054571831846_2840887.0RegionLoop-1
TgeneSCAPchr6:43501644chr3:47464026ENST00000545718318535_7100887.0RegionLoop-7
TgeneSCAPchr6:43501644chr3:47464026ENST000002655658231005_10423831280.0RepeatNote=WD 3
TgeneSCAPchr6:43501644chr3:47464026ENST000002655658231077_11143831280.0RepeatNote=WD 4
TgeneSCAPchr6:43501644chr3:47464026ENST000002655658231117_11553831280.0RepeatNote=WD 5
TgeneSCAPchr6:43501644chr3:47464026ENST000002655658231158_11953831280.0RepeatNote=WD 6
TgeneSCAPchr6:43501644chr3:47464026ENST000002655658231197_12353831280.0RepeatNote=WD 7
TgeneSCAPchr6:43501644chr3:47464026ENST00000265565823771_8113831280.0RepeatNote=WD 1
TgeneSCAPchr6:43501644chr3:47464026ENST00000265565823952_10023831280.0RepeatNote=WD 2
TgeneSCAPchr6:43501644chr3:47464026ENST000005457183181005_10420887.0RepeatNote=WD 3
TgeneSCAPchr6:43501644chr3:47464026ENST000005457183181077_11140887.0RepeatNote=WD 4
TgeneSCAPchr6:43501644chr3:47464026ENST000005457183181117_11550887.0RepeatNote=WD 5
TgeneSCAPchr6:43501644chr3:47464026ENST000005457183181158_11950887.0RepeatNote=WD 6
TgeneSCAPchr6:43501644chr3:47464026ENST000005457183181197_12350887.0RepeatNote=WD 7
TgeneSCAPchr6:43501644chr3:47464026ENST00000545718318771_8110887.0RepeatNote=WD 1
TgeneSCAPchr6:43501644chr3:47464026ENST00000545718318952_10020887.0RepeatNote=WD 2
TgeneSCAPchr6:43501644chr3:47464026ENST00000265565823423_4233831280.0Topological domainLumenal
TgeneSCAPchr6:43501644chr3:47464026ENST00000265565823445_5183831280.0Topological domainCytoplasmic
TgeneSCAPchr6:43501644chr3:47464026ENST00000265565823540_7093831280.0Topological domainLumenal
TgeneSCAPchr6:43501644chr3:47464026ENST000005457183181_180887.0Topological domainCytoplasmic
TgeneSCAPchr6:43501644chr3:47464026ENST00000545718318301_3120887.0Topological domainCytoplasmic
TgeneSCAPchr6:43501644chr3:47464026ENST00000545718318334_3440887.0Topological domainLumenal
TgeneSCAPchr6:43501644chr3:47464026ENST00000545718318366_4010887.0Topological domainCytoplasmic
TgeneSCAPchr6:43501644chr3:47464026ENST0000054571831840_2790887.0Topological domainLumenal
TgeneSCAPchr6:43501644chr3:47464026ENST00000545718318423_4230887.0Topological domainLumenal
TgeneSCAPchr6:43501644chr3:47464026ENST00000545718318445_5180887.0Topological domainCytoplasmic
TgeneSCAPchr6:43501644chr3:47464026ENST00000545718318540_7090887.0Topological domainLumenal
TgeneSCAPchr6:43501644chr3:47464026ENST00000265565823402_4223831280.0TransmembraneHelical%3B Name%3D5
TgeneSCAPchr6:43501644chr3:47464026ENST00000265565823424_4443831280.0TransmembraneHelical%3B Name%3D6
TgeneSCAPchr6:43501644chr3:47464026ENST00000265565823519_5393831280.0TransmembraneHelical%3B Name%3D7
TgeneSCAPchr6:43501644chr3:47464026ENST00000265565823710_7303831280.0TransmembraneHelical%3B Name%3D8
TgeneSCAPchr6:43501644chr3:47464026ENST0000054571831819_390887.0TransmembraneHelical%3B Name%3D1
TgeneSCAPchr6:43501644chr3:47464026ENST00000545718318280_3000887.0TransmembraneHelical%3B Name%3D2
TgeneSCAPchr6:43501644chr3:47464026ENST00000545718318313_3330887.0TransmembraneHelical%3B Name%3D3
TgeneSCAPchr6:43501644chr3:47464026ENST00000545718318345_3650887.0TransmembraneHelical%3B Name%3D4
TgeneSCAPchr6:43501644chr3:47464026ENST00000545718318402_4220887.0TransmembraneHelical%3B Name%3D5
TgeneSCAPchr6:43501644chr3:47464026ENST00000545718318424_4440887.0TransmembraneHelical%3B Name%3D6
TgeneSCAPchr6:43501644chr3:47464026ENST00000545718318519_5390887.0TransmembraneHelical%3B Name%3D7
TgeneSCAPchr6:43501644chr3:47464026ENST00000545718318710_7300887.0TransmembraneHelical%3B Name%3D8

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneSCAPchr6:43501644chr3:47464026ENST00000265565823284_4423831280.0DomainSSD
TgeneSCAPchr6:43501644chr3:47464026ENST0000026556582346_2843831280.0RegionLoop-1
TgeneSCAPchr6:43501644chr3:47464026ENST000002655658231_183831280.0Topological domainCytoplasmic
TgeneSCAPchr6:43501644chr3:47464026ENST00000265565823301_3123831280.0Topological domainCytoplasmic
TgeneSCAPchr6:43501644chr3:47464026ENST00000265565823334_3443831280.0Topological domainLumenal
TgeneSCAPchr6:43501644chr3:47464026ENST00000265565823366_4013831280.0Topological domainCytoplasmic
TgeneSCAPchr6:43501644chr3:47464026ENST0000026556582340_2793831280.0Topological domainLumenal
TgeneSCAPchr6:43501644chr3:47464026ENST0000026556582319_393831280.0TransmembraneHelical%3B Name%3D1
TgeneSCAPchr6:43501644chr3:47464026ENST00000265565823280_3003831280.0TransmembraneHelical%3B Name%3D2
TgeneSCAPchr6:43501644chr3:47464026ENST00000265565823313_3333831280.0TransmembraneHelical%3B Name%3D3
TgeneSCAPchr6:43501644chr3:47464026ENST00000265565823345_3653831280.0TransmembraneHelical%3B Name%3D4


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Fusion Gene Sequence for XPO5-SCAP


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>99682_99682_1_XPO5-SCAP_XPO5_chr6_43501644_ENST00000265351_SCAP_chr3_47464026_ENST00000265565_length(transcript)=5485nt_BP=2654nt
ACTTCCGCGGGCGCGTGCGCAGTGGCGGGCCGGGCGCGTGCGCAGCGCCGGCTTCTTCCCAGCGCGAGTTGCTGCTAACGCTCCTCCTCC
AGCTTCCCACCCCCGCCGCCCGCCGCGGCCCGGTACCAACGGGTGGTCTCGCCGAGGGAGCTGTCGTGCCTCGTGGTCCCGGGACTGCAG
TGGTGTGCGCTCTCGGCGCGTGGCGCTAGGCATGGCGATGGATCAAGTAAACGCGCTGTGCGAGCAGCTGGTGAAAGCGGTGACGGTCAT
GATGGACCCCAACTCCACCCAGCGCTACCGGCTGGAAGCCCTCAAGTTTTGTGAGGAGTTTAAAGAAAAGTGTCCTATCTGTGTCCCCTG
TGGCTTGAGGTTGGCTGAGAAAACACAAGTTGCCATCGTCAGACATTTTGGCCTTCAGATCCTGGAACACGTTGTCAAGTTTCGGTGGAA
CGGCATGTCTCGATTGGAGAAGGTGTATCTGAAGAACAGTGTCATGGAGCTGATTGCAAATGGAACATTGAACATTTTGGAAGAGGAGAA
CCATATTAAAGATGCTCTGTCTCGAATTGTAGTGGAAATGATCAAGCGAGAGTGGCCACAGCATTGGCCTGACATGCTAATAGAATTGGA
CACTCTTTCCAAACAAGGGGAAACACAGACAGAATTGGTGATGTTTATCCTTTTGCGACTGGCAGAGGATGTAGTGACTTTTCAGACACT
TCCCCCTCAAAGAAGAAGGGACATCCAGCAAACATTAACCCAGAACATGGAAAGGATCTTCAGTTTTCTGCTTAACACACTTCAAGAAAA
TGTAAACAAGTATCAGCAAGTGAAGACAGATACTTCTCAGGAGTCAAAGGCGCAAGCAAACTGTCGAGTAGGAGTTGCAGCACTGAATAC
TCTAGCAGGCTATATTGACTGGGTGTCTATGAGTCACATCACTGCTGAAAACTGTAAACTCCTGGAGATACTGTGTTTGCTGTTGAATGA
ACAGGAACTTCAGTTGGGAGCCGCTGAGTGTCTTCTCATTGCAGTCAGCAGAAAAGGCAAGTTGGAAGACCGGAAGCCCTTGATGGTCTT
ATTTGGAGATGTTGCCATGCATTATATACTCTCCGCCGCACAGACTGCTGATGGAGGAGGTTTGGTAGAAAAACACTACGTCTTTCTGAA
GAGGCTCTGTCAGGTGTTGTGTGCGCTGGGCAATCAGCTGTGTGCATTGCTGGGTGCAGATTCTGATGTAGAAACACCATCAAACTTTGG
AAAATACCTGGAATCTTTTCTTGCTTTCACAACCCATCCAAGTCAGTTTCTACGCTCTTCAACTCAGATGACTTGGGGAGCCCTCTTCAG
GCATGAAATCCTGTCCCGTGATCCTTTGCTATTAGCAATAATACCAAAATATCTTCGTGCTTCCATGACTAACTTGGTCAAGATGGGCTT
TCCTTCTAAAACAGACAGCCCTAGCTGTGAATATTCTCGGTTTGATTTTGATAGCGATGAGGACTTCAATGCTTTCTTCAACTCCTCCCG
AGCACAACAAGGAGAGGTGATGAGGTTGGCATGTCGTTTGGATCCCAAAACTAGCTTCCAGATGGCTGGGGAGTGGCTAAAGTATCAACT
ATCAACTTTTCTTGATGCTGGTTCTGTGAATTCTTGTTCTGCAGTTGGAACTGGAGAAGGAAGCCTCTGTTCCGTCTTCTCACCTTCATT
CGTGCAGTGGGAAGCCATGACTCTTTTTTTGGAAAGTGTTATCACCCAGATGTTTCGAACACTAAATAGAGAAGAAATTCCTGTTAATGA
TGGAATAGAGCTATTGCAGATGGTTCTGAACTTTGATACCAAGGATCCCCTCATCCTGTCCTGCGTCCTTACTAATGTCTCTGCACTCTT
TCCATTTGTCACCTACAGACCAGAGTTCCTGCCCCAGGTCTTCTCTAAGCTATTTTCATCTGTCACTTTTGAAACTGTTGAAGAAAGTAA
GGCCCCCAGAACCCGGGCAGTGAGGAATGTGAGGAGGCATGCTTGTTCCTCCATCATCAAGATGTGTCGTGACTACCCCCAGCTTGTGCT
GCCCAATTTTGACATGCTTTATAACCATGTGAAGCAACTCCTCTCCAATGAGCTACTCCTGACACAAATGGAGAAGTGTGCCCTCATGGA
AGCCCTGGTTCTCATTAGCAACCAATTTAAGAACTACGAGCGTCAGAAGGTGTTCCTAGAGGAGCTGATGGCACCAGTGGCCAGCATCTG
GCTTTCTCAAGACATGCACAGAGTGCTGTCAGATGTTGATGCTTTCATTGCGTATGTGGGTACAGATCAGAAGAGCTGTGACCCAGGCCT
GGAGGATCCGTGTGGCTTAAACCGTGCACGAATGAGCTTTTGTGTATACAGCATTCTGGGTGTGGTGAAACGAACTTGCTGGCCCACTGA
CCTAGAAGAGGCCAAAGCTGGGGGATTTGTGGTGGGTTATACATCCAGTGGAAATCCAATCTTCCGTAACCCCTGCACAGAGCAGATTCT
GAAACTTCTTGACAATTTGCTTGCGCTTATAAGAACCCACAATACATTATATGCACCAGAAATGCTAGCCAAAATGGCAGAGCCTTTCAC
CAAGGCTCTGGATATGCTTGACGCGGAAAAATCTGCTATATTAGGCCTAAGCAGCGAGAGCTGGTCCATCATGAAGAACATGGCCACGGA
GCTGGGCATCATCCTCATCGGCTACTTCACCCTAGTGCCCGCCATCCAGGAGTTCTGTCTCTTTGCTGTCGTGGGGCTGGTGTCTGACTT
CTTCCTTCAGATGCTGTTTTTCACCACTGTCCTGTCCATTGACATTCGCCGGATGGAGCTAGCAGACCTGAACAAGCGACTGCCCCCTGA
GGCCTGCCTGCCCTCAGCCAAGCCAGTGGGACAGCCAACGCGCTACGAGCGGCAGCTGGCTGTGAGGCCGTCCACACCCCACACCATCAC
GTTGCAGCCGTCTTCCTTCCGAAACCTGCGGCTCCCCAAGAGGCTGCGTGTTGTCTACTTCCTGGCCCGCACCCGCCTGGCACAGCGCCT
CATCATGGCTGGCACCGTTGTCTGGATTGGCATCCTGGTATACACAGACCCAGCAGGGCTGCGCAACTACCTCGCTGCCCAGGTGACGGA
ACAGAGCCCATTGGGTGAGGGAGCCCTGGCTCCCATGCCCGTGCCTAGTGGCATGCTGCCCCCCAGCCACCCGGACCCTGCCTTCTCCAT
CTTCCCACCTGATGCCCCTAAGCTACCTGAGAACCAGACGTCGCCAGGCGAGTCACCTGAGCGTGGAGGTCCAGCAGAGGTTGTCCATGA
CAGCCCAGTCCCAGAGGTAACCTGGGGGCCTGAGGATGAGGAACTTTGGAGGAAATTGTCCTTCCGCCACTGGCCGACGCTCTTCAGCTA
TTACAACATCACACTGGCCAAGAGGTACATCAGCCTGCTGCCCGTCATCCCAGTCACGCTCCGCCTGAACCCGAGGGAGGCTCTGGAGGG
CCGGCACCCTCAGGACGGCCGCAGTGCCTGGCCCCCACCGGGGCCCATACCTGCTGGGCACTGGGAAGCAGGACCCAAGGGCCCAGGTGG
GGTGCAGGCCCATGGAGACGTCACGCTGTACAAGGTGGCGGCGCTGGGCCTGGCCACCGGCATCGTCTTGGTGCTGCTGCTGCTCTGCCT
CTACCGCGTGCTATGCCCGCGCAACTACGGGCAGCTGGGTGGTGGGCCCGGGCGGCGGAGGCGCGGGGAGCTGCCCTGCGACGACTACGG
CTATGCGCCACCCGAGACGGAGATCGTGCCGCTTGTGCTGCGCGGCCACCTCATGGACATCGAGTGCCTGGCCAGCGACGGCATGCTGCT
GGTGAGCTGCTGCCTGGCAGGCCACGTCTGCGTGTGGGACGCGCAGACCGGGGATTGCCTAACGCGCATTCCGCGCCCAGGCAGGCAGCG
CCGGGACAGTGGCGTGGGCAGCGGGCTTGAGGCTCAGGAGAGCTGGGAACGACTTTCAGATGGTGGGAAGGCTGGTCCAGAGGAGCCTGG
GGACAGCCCTCCCCTGAGACACCGCCCCCGGGGCCCTCCGCCGCCTTCCCTCTTCGGGGACCAGCCTGACCTCACCTGCTTAATTGACAC
CAACTTTTCAGCGCAGCCTCGGTCCTCACAGCCCACTCAGCCCGAGCCCCGGCACCGGGCGGTCTGTGGCCGCTCTCGGGACTCCCCAGG
CTATGACTTCAGCTGCCTGGTGCAGCGGGTGTACCAGGAGGAGGGGCTGGCGGCCGTCTGCACACCAGCCCTGCGCCCACCCTCGCCTGG
GCCGGTGCTGTCCCAGGCCCCTGAGGACGAGGGTGGCTCCCCCGAGAAAGGCTCCCCTTCCCTCGCCTGGGCCCCCAGTGCCGAGGGTTC
CATCTGGAGCTTGGAGCTGCAGGGCAACCTCATCGTGGTGGGGCGGAGCAGCGGCCGGCTGGAGGTGTGGGACGCCATTGAAGGGGTGCT
GTGCTGCAGCAGCGAGGAGGTCTCCTCAGGCATTACCGCTCTGGTGTTCTTGGACAAAAGGATTGTGGCTGCACGGCTCAACGGTTCCCT
TGATTTCTTCTCCTTGGAGACCCACACTGCCCTCAGCCCCCTGCAGTTTAGAGGGACCCCAGGGCGGGGCAGTTCCCCTGCCTCTCCAGT
GTACAGCAGCAGCGACACAGTGGCCTGTCACCTGACCCACACAGTGCCCTGTGCACACCAAAAACCCATCACAGCCCTGAAAGCCGCTGC
TGGGCGCTTGGTGACTGGGAGCCAAGACCACACACTGAGAGTGTTCCGTCTGGAGGACTCGTGCTGCCTCTTCACCCTTCAGGGCCACTC
AGGGGCCATCACGACCGTGTACATTGACCAGACCATGGTGCTGGCCAGTGGAGGACAAGATGGGGCCATCTGCCTGTGGGATGTACTGAC
TGGCAGCCGGGTCAGCCATGTGTTTGCTCACCGTGGGGATGTCACCTCCCTTACCTGTACCACCTCCTGTGTCATCAGCAGTGGCCTGGA
TGACCTCATCAGCATCTGGGACCGCAGCACAGGCATCAAGTTCTACTCCATTCAGCAGGACCTGGGCTGTGGTGCAAGCTTGGGTGTCAT
CTCAGACAACCTGCTGGTGACTGGCGGCCAGGGCTGTGTCTCCTTTTGGGACCTAAACTACGGGGACCTGTTACAGACAGTCTACCTGGG
GAAGAACAGTGAGGCCCAGCCTGCCCGCCAGATCCTGGTGCTGGACAACGCTGCCATTGTCTGCAACTTTGGCAGTGAGCTCAGCCTGGT
GTATGTGCCCTCTGTGCTGGAGAAGCTGGACTGAGCGCAGGGCCTCCTTGCCCAGGCAGGAGGCTGGGGTGCTGTGTGGGGGCCAATGCA

>99682_99682_1_XPO5-SCAP_XPO5_chr6_43501644_ENST00000265351_SCAP_chr3_47464026_ENST00000265565_length(amino acids)=1710AA_BP=814
MAMDQVNALCEQLVKAVTVMMDPNSTQRYRLEALKFCEEFKEKCPICVPCGLRLAEKTQVAIVRHFGLQILEHVVKFRWNGMSRLEKVYL
KNSVMELIANGTLNILEEENHIKDALSRIVVEMIKREWPQHWPDMLIELDTLSKQGETQTELVMFILLRLAEDVVTFQTLPPQRRRDIQQ
TLTQNMERIFSFLLNTLQENVNKYQQVKTDTSQESKAQANCRVGVAALNTLAGYIDWVSMSHITAENCKLLEILCLLLNEQELQLGAAEC
LLIAVSRKGKLEDRKPLMVLFGDVAMHYILSAAQTADGGGLVEKHYVFLKRLCQVLCALGNQLCALLGADSDVETPSNFGKYLESFLAFT
THPSQFLRSSTQMTWGALFRHEILSRDPLLLAIIPKYLRASMTNLVKMGFPSKTDSPSCEYSRFDFDSDEDFNAFFNSSRAQQGEVMRLA
CRLDPKTSFQMAGEWLKYQLSTFLDAGSVNSCSAVGTGEGSLCSVFSPSFVQWEAMTLFLESVITQMFRTLNREEIPVNDGIELLQMVLN
FDTKDPLILSCVLTNVSALFPFVTYRPEFLPQVFSKLFSSVTFETVEESKAPRTRAVRNVRRHACSSIIKMCRDYPQLVLPNFDMLYNHV
KQLLSNELLLTQMEKCALMEALVLISNQFKNYERQKVFLEELMAPVASIWLSQDMHRVLSDVDAFIAYVGTDQKSCDPGLEDPCGLNRAR
MSFCVYSILGVVKRTCWPTDLEEAKAGGFVVGYTSSGNPIFRNPCTEQILKLLDNLLALIRTHNTLYAPEMLAKMAEPFTKALDMLDAEK
SAILGLSSESWSIMKNMATELGIILIGYFTLVPAIQEFCLFAVVGLVSDFFLQMLFFTTVLSIDIRRMELADLNKRLPPEACLPSAKPVG
QPTRYERQLAVRPSTPHTITLQPSSFRNLRLPKRLRVVYFLARTRLAQRLIMAGTVVWIGILVYTDPAGLRNYLAAQVTEQSPLGEGALA
PMPVPSGMLPPSHPDPAFSIFPPDAPKLPENQTSPGESPERGGPAEVVHDSPVPEVTWGPEDEELWRKLSFRHWPTLFSYYNITLAKRYI
SLLPVIPVTLRLNPREALEGRHPQDGRSAWPPPGPIPAGHWEAGPKGPGGVQAHGDVTLYKVAALGLATGIVLVLLLLCLYRVLCPRNYG
QLGGGPGRRRRGELPCDDYGYAPPETEIVPLVLRGHLMDIECLASDGMLLVSCCLAGHVCVWDAQTGDCLTRIPRPGRQRRDSGVGSGLE
AQESWERLSDGGKAGPEEPGDSPPLRHRPRGPPPPSLFGDQPDLTCLIDTNFSAQPRSSQPTQPEPRHRAVCGRSRDSPGYDFSCLVQRV
YQEEGLAAVCTPALRPPSPGPVLSQAPEDEGGSPEKGSPSLAWAPSAEGSIWSLELQGNLIVVGRSSGRLEVWDAIEGVLCCSSEEVSSG
ITALVFLDKRIVAARLNGSLDFFSLETHTALSPLQFRGTPGRGSSPASPVYSSSDTVACHLTHTVPCAHQKPITALKAAAGRLVTGSQDH
TLRVFRLEDSCCLFTLQGHSGAITTVYIDQTMVLASGGQDGAICLWDVLTGSRVSHVFAHRGDVTSLTCTTSCVISSGLDDLISIWDRST
GIKFYSIQQDLGCGASLGVISDNLLVTGGQGCVSFWDLNYGDLLQTVYLGKNSEAQPARQILVLDNAAIVCNFGSELSLVYVPSVLEKLD

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>99682_99682_2_XPO5-SCAP_XPO5_chr6_43501644_ENST00000265351_SCAP_chr3_47464026_ENST00000441517_length(transcript)=5474nt_BP=2654nt
ACTTCCGCGGGCGCGTGCGCAGTGGCGGGCCGGGCGCGTGCGCAGCGCCGGCTTCTTCCCAGCGCGAGTTGCTGCTAACGCTCCTCCTCC
AGCTTCCCACCCCCGCCGCCCGCCGCGGCCCGGTACCAACGGGTGGTCTCGCCGAGGGAGCTGTCGTGCCTCGTGGTCCCGGGACTGCAG
TGGTGTGCGCTCTCGGCGCGTGGCGCTAGGCATGGCGATGGATCAAGTAAACGCGCTGTGCGAGCAGCTGGTGAAAGCGGTGACGGTCAT
GATGGACCCCAACTCCACCCAGCGCTACCGGCTGGAAGCCCTCAAGTTTTGTGAGGAGTTTAAAGAAAAGTGTCCTATCTGTGTCCCCTG
TGGCTTGAGGTTGGCTGAGAAAACACAAGTTGCCATCGTCAGACATTTTGGCCTTCAGATCCTGGAACACGTTGTCAAGTTTCGGTGGAA
CGGCATGTCTCGATTGGAGAAGGTGTATCTGAAGAACAGTGTCATGGAGCTGATTGCAAATGGAACATTGAACATTTTGGAAGAGGAGAA
CCATATTAAAGATGCTCTGTCTCGAATTGTAGTGGAAATGATCAAGCGAGAGTGGCCACAGCATTGGCCTGACATGCTAATAGAATTGGA
CACTCTTTCCAAACAAGGGGAAACACAGACAGAATTGGTGATGTTTATCCTTTTGCGACTGGCAGAGGATGTAGTGACTTTTCAGACACT
TCCCCCTCAAAGAAGAAGGGACATCCAGCAAACATTAACCCAGAACATGGAAAGGATCTTCAGTTTTCTGCTTAACACACTTCAAGAAAA
TGTAAACAAGTATCAGCAAGTGAAGACAGATACTTCTCAGGAGTCAAAGGCGCAAGCAAACTGTCGAGTAGGAGTTGCAGCACTGAATAC
TCTAGCAGGCTATATTGACTGGGTGTCTATGAGTCACATCACTGCTGAAAACTGTAAACTCCTGGAGATACTGTGTTTGCTGTTGAATGA
ACAGGAACTTCAGTTGGGAGCCGCTGAGTGTCTTCTCATTGCAGTCAGCAGAAAAGGCAAGTTGGAAGACCGGAAGCCCTTGATGGTCTT
ATTTGGAGATGTTGCCATGCATTATATACTCTCCGCCGCACAGACTGCTGATGGAGGAGGTTTGGTAGAAAAACACTACGTCTTTCTGAA
GAGGCTCTGTCAGGTGTTGTGTGCGCTGGGCAATCAGCTGTGTGCATTGCTGGGTGCAGATTCTGATGTAGAAACACCATCAAACTTTGG
AAAATACCTGGAATCTTTTCTTGCTTTCACAACCCATCCAAGTCAGTTTCTACGCTCTTCAACTCAGATGACTTGGGGAGCCCTCTTCAG
GCATGAAATCCTGTCCCGTGATCCTTTGCTATTAGCAATAATACCAAAATATCTTCGTGCTTCCATGACTAACTTGGTCAAGATGGGCTT
TCCTTCTAAAACAGACAGCCCTAGCTGTGAATATTCTCGGTTTGATTTTGATAGCGATGAGGACTTCAATGCTTTCTTCAACTCCTCCCG
AGCACAACAAGGAGAGGTGATGAGGTTGGCATGTCGTTTGGATCCCAAAACTAGCTTCCAGATGGCTGGGGAGTGGCTAAAGTATCAACT
ATCAACTTTTCTTGATGCTGGTTCTGTGAATTCTTGTTCTGCAGTTGGAACTGGAGAAGGAAGCCTCTGTTCCGTCTTCTCACCTTCATT
CGTGCAGTGGGAAGCCATGACTCTTTTTTTGGAAAGTGTTATCACCCAGATGTTTCGAACACTAAATAGAGAAGAAATTCCTGTTAATGA
TGGAATAGAGCTATTGCAGATGGTTCTGAACTTTGATACCAAGGATCCCCTCATCCTGTCCTGCGTCCTTACTAATGTCTCTGCACTCTT
TCCATTTGTCACCTACAGACCAGAGTTCCTGCCCCAGGTCTTCTCTAAGCTATTTTCATCTGTCACTTTTGAAACTGTTGAAGAAAGTAA
GGCCCCCAGAACCCGGGCAGTGAGGAATGTGAGGAGGCATGCTTGTTCCTCCATCATCAAGATGTGTCGTGACTACCCCCAGCTTGTGCT
GCCCAATTTTGACATGCTTTATAACCATGTGAAGCAACTCCTCTCCAATGAGCTACTCCTGACACAAATGGAGAAGTGTGCCCTCATGGA
AGCCCTGGTTCTCATTAGCAACCAATTTAAGAACTACGAGCGTCAGAAGGTGTTCCTAGAGGAGCTGATGGCACCAGTGGCCAGCATCTG
GCTTTCTCAAGACATGCACAGAGTGCTGTCAGATGTTGATGCTTTCATTGCGTATGTGGGTACAGATCAGAAGAGCTGTGACCCAGGCCT
GGAGGATCCGTGTGGCTTAAACCGTGCACGAATGAGCTTTTGTGTATACAGCATTCTGGGTGTGGTGAAACGAACTTGCTGGCCCACTGA
CCTAGAAGAGGCCAAAGCTGGGGGATTTGTGGTGGGTTATACATCCAGTGGAAATCCAATCTTCCGTAACCCCTGCACAGAGCAGATTCT
GAAACTTCTTGACAATTTGCTTGCGCTTATAAGAACCCACAATACATTATATGCACCAGAAATGCTAGCCAAAATGGCAGAGCCTTTCAC
CAAGGCTCTGGATATGCTTGACGCGGAAAAATCTGCTATATTAGGCCTAAGCAGCGAGAGCTGGTCCATCATGAAGAACATGGCCACGGA
GCTGGGCATCATCCTCATCGGCTACTTCACCCTAGTGCCCGCCATCCAGGAGTTCTGTCTCTTTGCTGTCGTGGGGCTGGTGTCTGACTT
CTTCCTTCAGATGCTGTTTTTCACCACTGTCCTGTCCATTGACATTCGCCGGATGGAGCTAGCAGACCTGAACAAGCGACTGCCCCCTGA
GGCCTGCCTGCCCTCAGCCAAGCCAGTGGGACAGCCAACGCGCTACGAGCGGCAGCTGGCTGTGAGGCCGTCCACACCCCACACCATCAC
GTTGCAGCCGTCTTCCTTCCGAAACCTGCGGCTCCCCAAGAGGCTGCGTGTTGTCTACTTCCTGGCCCGCACCCGCCTGGCACAGCGCCT
CATCATGGCTGGCACCGTTGTCTGGATTGGCATCCTGGTATACACAGACCCAGCAGGGCTGCGCAACTACCTCGCTGCCCAGGTGACGGA
ACAGAGCCCATTGGGTGAGGGAGCCCTGGCTCCCATGCCCGTGCCTAGTGGCATGCTGCCCCCCAGCCACCCGGACCCTGCCTTCTCCAT
CTTCCCACCTGATGCCCCTAAGCTACCTGAGAACCAGACGTCGCCAGGCGAGTCACCTGAGCGTGGAGGTCCAGCAGAGGTTGTCCATGA
CAGCCCAGTCCCAGAGGTAACCTGGGGGCCTGAGGATGAGGAACTTTGGAGGAAATTGTCCTTCCGCCACTGGCCGACGCTCTTCAGCTA
TTACAACATCACACTGGCCAAGAGGTACATCAGCCTGCTGCCCGTCATCCCAGTCACGCTCCGCCTGAACCCGAGGGAGGCTCTGGAGGG
CCGGCACCCTCAGGACGGCCGCAGTGCCTGGCCCCCACCGGGGCCCATACCTGCTGGGCACTGGGAAGCAGGACCCAAGGGCCCAGGTGG
GGTGCAGGCCCATGGAGACGTCACGCTGTACAAGGTGGCGGCGCTGGGCCTGGCCACCGGCATCGTCTTGGTGCTGCTGCTGCTCTGCCT
CTACCGCGTGCTATGCCCGCGCAACTACGGGCAGCTGGGTGGTGGGCCCGGGCGGCGGAGGCGCGGGGAGCTGCCCTGCGACGACTACGG
CTATGCGCCACCCGAGACGGAGATCGTGCCGCTTGTGCTGCGCGGCCACCTCATGGACATCGAGTGCCTGGCCAGCGACGGCATGCTGCT
GGTGAGCTGCTGCCTGGCAGGCCACGTCTGCGTGTGGGACGCGCAGACCGGGGATTGCCTAACGCGCATTCCGCGCCCAGGGCAGCGCCG
GGACAGTGGCGTGGGCAGCGGGCTTGAGGCTCAGGAGAGCTGGGAACGACTTTCAGATGGTGGGAAGGCTGGTCCAGAGGAGCCTGGGGA
CAGCCCTCCCCTGAGACACCGCCCCCGGGGCCCTCCGCCGCCTTCCCTCTTCGGGGACCAGCCTGACCTCACCTGCTTAATTGACACCAA
CTTTTCAGCGCAGCCTCGGTCCTCACAGCCCACTCAGCCCGAGCCCCGGCACCGGGCGGTCTGTGGCCGCTCTCGGGACTCCCCAGGCTA
TGACTTCAGCTGCCTGGTGCAGCGGGTGTACCAGGAGGAGGGGCTGGCGGCCGTCTGCACACCAGCCCTGCGCCCACCCTCGCCTGGGCC
GGTGCTGTCCCAGGCCCCTGAGGACGAGGGTGGCTCCCCCGAGAAAGGCTCCCCTTCCCTCGCCTGGGCCCCCAGTGCCGAGGGTTCCAT
CTGGAGCTTGGAGCTGCAGGGCAACCTCATCGTGGTGGGGCGGAGCAGCGGCCGGCTGGAGGTGTGGGACGCCATTGAAGGGGTGCTGTG
CTGCAGCAGCGAGGAGGTCTCCTCAGGCATTACCGCTCTGGTGTTCTTGGACAAAAGGATTGTGGCTGCACGGCTCAACGGTTCCCTTGA
TTTCTTCTCCTTGGAGACCCACACTGCCCTCAGCCCCCTGCAGTTTAGAGGGACCCCAGGGCGGGGCAGTTCCCCTGCCTCTCCAGTGTA
CAGCAGCAGCGACACAGTGGCCTGTCACCTGACCCACACAGTGCCCTGTGCACACCAAAAACCCATCACAGCCCTGAAAGCCGCTGCTGG
GCGCTTGGTGACTGGGAGCCAAGACCACACACTGAGAGTGTTCCGTCTGGAGGACTCGTGCTGCCTCTTCACCCTTCAGGGCCACTCAGG
GGCCATCACGACCGTGTACATTGACCAGACCATGGTGCTGGCCAGTGGAGGACAAGATGGGGCCATCTGCCTGTGGGATGTACTGACTGG
CAGCCGGGTCAGCCATGTGTTTGCTCACCGTGGGGATGTCACCTCCCTTACCTGTACCACCTCCTGTGTCATCAGCAGTGGCCTGGATGA
CCTCATCAGCATCTGGGACCGCAGCACAGGCATCAAGTTCTACTCCATTCAGCAGGACCTGGGCTGTGGTGCAAGCTTGGGTGTCATCTC
AGACAACCTGCTGGTGACTGGCGGCCAGGGCTGTGTCTCCTTTTGGGACCTAAACTACGGGGACCTGTTACAGACAGTCTACCTGGGGAA
GAACAGTGAGGCCCAGCCTGCCCGCCAGATCCTGGTGCTGGACAACGCTGCCATTGTCTGCAACTTTGGCAGTGAGCTCAGCCTGGTGTA
TGTGCCCTCTGTGCTGGAGAAGCTGGACTGAGCGCAGGGCCTCCTTGCCCAGGCAGGAGGCTGGGGTGCTGTGTGGGGGCCAATGCACTG

>99682_99682_2_XPO5-SCAP_XPO5_chr6_43501644_ENST00000265351_SCAP_chr3_47464026_ENST00000441517_length(amino acids)=1709AA_BP=814
MAMDQVNALCEQLVKAVTVMMDPNSTQRYRLEALKFCEEFKEKCPICVPCGLRLAEKTQVAIVRHFGLQILEHVVKFRWNGMSRLEKVYL
KNSVMELIANGTLNILEEENHIKDALSRIVVEMIKREWPQHWPDMLIELDTLSKQGETQTELVMFILLRLAEDVVTFQTLPPQRRRDIQQ
TLTQNMERIFSFLLNTLQENVNKYQQVKTDTSQESKAQANCRVGVAALNTLAGYIDWVSMSHITAENCKLLEILCLLLNEQELQLGAAEC
LLIAVSRKGKLEDRKPLMVLFGDVAMHYILSAAQTADGGGLVEKHYVFLKRLCQVLCALGNQLCALLGADSDVETPSNFGKYLESFLAFT
THPSQFLRSSTQMTWGALFRHEILSRDPLLLAIIPKYLRASMTNLVKMGFPSKTDSPSCEYSRFDFDSDEDFNAFFNSSRAQQGEVMRLA
CRLDPKTSFQMAGEWLKYQLSTFLDAGSVNSCSAVGTGEGSLCSVFSPSFVQWEAMTLFLESVITQMFRTLNREEIPVNDGIELLQMVLN
FDTKDPLILSCVLTNVSALFPFVTYRPEFLPQVFSKLFSSVTFETVEESKAPRTRAVRNVRRHACSSIIKMCRDYPQLVLPNFDMLYNHV
KQLLSNELLLTQMEKCALMEALVLISNQFKNYERQKVFLEELMAPVASIWLSQDMHRVLSDVDAFIAYVGTDQKSCDPGLEDPCGLNRAR
MSFCVYSILGVVKRTCWPTDLEEAKAGGFVVGYTSSGNPIFRNPCTEQILKLLDNLLALIRTHNTLYAPEMLAKMAEPFTKALDMLDAEK
SAILGLSSESWSIMKNMATELGIILIGYFTLVPAIQEFCLFAVVGLVSDFFLQMLFFTTVLSIDIRRMELADLNKRLPPEACLPSAKPVG
QPTRYERQLAVRPSTPHTITLQPSSFRNLRLPKRLRVVYFLARTRLAQRLIMAGTVVWIGILVYTDPAGLRNYLAAQVTEQSPLGEGALA
PMPVPSGMLPPSHPDPAFSIFPPDAPKLPENQTSPGESPERGGPAEVVHDSPVPEVTWGPEDEELWRKLSFRHWPTLFSYYNITLAKRYI
SLLPVIPVTLRLNPREALEGRHPQDGRSAWPPPGPIPAGHWEAGPKGPGGVQAHGDVTLYKVAALGLATGIVLVLLLLCLYRVLCPRNYG
QLGGGPGRRRRGELPCDDYGYAPPETEIVPLVLRGHLMDIECLASDGMLLVSCCLAGHVCVWDAQTGDCLTRIPRPGQRRDSGVGSGLEA
QESWERLSDGGKAGPEEPGDSPPLRHRPRGPPPPSLFGDQPDLTCLIDTNFSAQPRSSQPTQPEPRHRAVCGRSRDSPGYDFSCLVQRVY
QEEGLAAVCTPALRPPSPGPVLSQAPEDEGGSPEKGSPSLAWAPSAEGSIWSLELQGNLIVVGRSSGRLEVWDAIEGVLCCSSEEVSSGI
TALVFLDKRIVAARLNGSLDFFSLETHTALSPLQFRGTPGRGSSPASPVYSSSDTVACHLTHTVPCAHQKPITALKAAAGRLVTGSQDHT
LRVFRLEDSCCLFTLQGHSGAITTVYIDQTMVLASGGQDGAICLWDVLTGSRVSHVFAHRGDVTSLTCTTSCVISSGLDDLISIWDRSTG

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Fusion Gene PPI Analysis for XPO5-SCAP


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneSCAPchr6:43501644chr3:47464026ENST00000265565823731_1279383.33333333333331280.0SREBF2
TgeneSCAPchr6:43501644chr3:47464026ENST00000545718318731_12790887.0SREBF2


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for XPO5-SCAP


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for XPO5-SCAP


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource