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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:XRCC6-GPX5 (FusionGDB2 ID:99780)

Fusion Gene Summary for XRCC6-GPX5

check button Fusion gene summary
Fusion gene informationFusion gene name: XRCC6-GPX5
Fusion gene ID: 99780
HgeneTgene
Gene symbol

XRCC6

GPX5

Gene ID

2547

2880

Gene nameX-ray repair cross complementing 6glutathione peroxidase 5
SynonymsCTC75|CTCBF|G22P1|KU70|ML8|TLAAEGLP|GPx-5|GSHPx-5|HEL-S-75p
Cytomap

22q13.2

6p22.1

Type of geneprotein-codingprotein-coding
DescriptionX-ray repair cross-complementing protein 65'-dRP lyase Ku705'-deoxyribose-5-phosphate lyase Ku7070 kDa subunit of Ku antigenATP-dependent DNA helicase 2 subunit 1ATP-dependent DNA helicase II, 70 kDa subunitCTC box binding factor 75 kDa subunitDNA epididymal secretory glutathione peroxidaseepididymal androgen-related proteinepididymis secretory sperm binding protein Li 75pepididymis-specific glutathione peroxidase-like protein
Modification date2020032920200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000359308, ENST00000360079, 
ENST00000402580, ENST00000405506, 
ENST00000405878, ENST00000428575, 
ENST00000442674, ENST00000550775, 
ENST00000551639, ENST00000412168, 
ENST00000469384, 
Fusion gene scores* DoF score12 X 10 X 8=9601 X 3 X 1=3
# samples 152
** MAII scorelog2(15/960*10)=-2.67807190511264
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(2/3*10)=2.73696559416621
Context

PubMed: XRCC6 [Title/Abstract] AND GPX5 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointXRCC6(42018090)-GPX5(28497228), # samples:2
Anticipated loss of major functional domain due to fusion event.XRCC6-GPX5 seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneXRCC6

GO:0002218

activation of innate immune response

28712728

HgeneXRCC6

GO:0045860

positive regulation of protein kinase activity

22504299

HgeneXRCC6

GO:0045893

positive regulation of transcription, DNA-templated

12145306

HgeneXRCC6

GO:0071480

cellular response to gamma radiation

26359349

HgeneXRCC6

GO:0097680

double-strand break repair via classical nonhomologous end joining

24095731


check buttonFusion gene breakpoints across XRCC6 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across GPX5 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-A7-A0DA-01AXRCC6chr22

42018090

+GPX5chr6

28497228

+
ChimerDB4BRCATCGA-A7-A0DA-01AXRCC6chr22

42018090

-GPX5chr6

28500098

+
ChimerDB4BRCATCGA-A7-A0DAXRCC6chr22

42018090

+GPX5chr6

28500097

+


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Fusion Gene ORF analysis for XRCC6-GPX5

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000359308ENST00000442674XRCC6chr22

42018090

+GPX5chr6

28497228

+
5CDS-3UTRENST00000359308ENST00000442674XRCC6chr22

42018090

-GPX5chr6

28500098

+
5CDS-3UTRENST00000359308ENST00000442674XRCC6chr22

42018090

+GPX5chr6

28500097

+
5CDS-3UTRENST00000360079ENST00000442674XRCC6chr22

42018090

+GPX5chr6

28497228

+
5CDS-3UTRENST00000360079ENST00000442674XRCC6chr22

42018090

-GPX5chr6

28500098

+
5CDS-3UTRENST00000360079ENST00000442674XRCC6chr22

42018090

+GPX5chr6

28500097

+
5CDS-3UTRENST00000402580ENST00000442674XRCC6chr22

42018090

+GPX5chr6

28497228

+
5CDS-3UTRENST00000402580ENST00000442674XRCC6chr22

42018090

-GPX5chr6

28500098

+
5CDS-3UTRENST00000402580ENST00000442674XRCC6chr22

42018090

+GPX5chr6

28500097

+
5CDS-3UTRENST00000405506ENST00000442674XRCC6chr22

42018090

+GPX5chr6

28497228

+
5CDS-3UTRENST00000405506ENST00000442674XRCC6chr22

42018090

-GPX5chr6

28500098

+
5CDS-3UTRENST00000405506ENST00000442674XRCC6chr22

42018090

+GPX5chr6

28500097

+
5CDS-3UTRENST00000405878ENST00000442674XRCC6chr22

42018090

+GPX5chr6

28497228

+
5CDS-3UTRENST00000405878ENST00000442674XRCC6chr22

42018090

-GPX5chr6

28500098

+
5CDS-3UTRENST00000405878ENST00000442674XRCC6chr22

42018090

+GPX5chr6

28500097

+
5CDS-intronENST00000359308ENST00000550775XRCC6chr22

42018090

+GPX5chr6

28497228

+
5CDS-intronENST00000359308ENST00000550775XRCC6chr22

42018090

-GPX5chr6

28500098

+
5CDS-intronENST00000359308ENST00000550775XRCC6chr22

42018090

+GPX5chr6

28500097

+
5CDS-intronENST00000359308ENST00000551639XRCC6chr22

42018090

+GPX5chr6

28497228

+
5CDS-intronENST00000359308ENST00000551639XRCC6chr22

42018090

-GPX5chr6

28500098

+
5CDS-intronENST00000359308ENST00000551639XRCC6chr22

42018090

+GPX5chr6

28500097

+
5CDS-intronENST00000360079ENST00000550775XRCC6chr22

42018090

+GPX5chr6

28497228

+
5CDS-intronENST00000360079ENST00000550775XRCC6chr22

42018090

-GPX5chr6

28500098

+
5CDS-intronENST00000360079ENST00000550775XRCC6chr22

42018090

+GPX5chr6

28500097

+
5CDS-intronENST00000360079ENST00000551639XRCC6chr22

42018090

+GPX5chr6

28497228

+
5CDS-intronENST00000360079ENST00000551639XRCC6chr22

42018090

-GPX5chr6

28500098

+
5CDS-intronENST00000360079ENST00000551639XRCC6chr22

42018090

+GPX5chr6

28500097

+
5CDS-intronENST00000402580ENST00000550775XRCC6chr22

42018090

+GPX5chr6

28497228

+
5CDS-intronENST00000402580ENST00000550775XRCC6chr22

42018090

-GPX5chr6

28500098

+
5CDS-intronENST00000402580ENST00000550775XRCC6chr22

42018090

+GPX5chr6

28500097

+
5CDS-intronENST00000402580ENST00000551639XRCC6chr22

42018090

+GPX5chr6

28497228

+
5CDS-intronENST00000402580ENST00000551639XRCC6chr22

42018090

-GPX5chr6

28500098

+
5CDS-intronENST00000402580ENST00000551639XRCC6chr22

42018090

+GPX5chr6

28500097

+
5CDS-intronENST00000405506ENST00000550775XRCC6chr22

42018090

+GPX5chr6

28497228

+
5CDS-intronENST00000405506ENST00000550775XRCC6chr22

42018090

-GPX5chr6

28500098

+
5CDS-intronENST00000405506ENST00000550775XRCC6chr22

42018090

+GPX5chr6

28500097

+
5CDS-intronENST00000405506ENST00000551639XRCC6chr22

42018090

+GPX5chr6

28497228

+
5CDS-intronENST00000405506ENST00000551639XRCC6chr22

42018090

-GPX5chr6

28500098

+
5CDS-intronENST00000405506ENST00000551639XRCC6chr22

42018090

+GPX5chr6

28500097

+
5CDS-intronENST00000405878ENST00000550775XRCC6chr22

42018090

+GPX5chr6

28497228

+
5CDS-intronENST00000405878ENST00000550775XRCC6chr22

42018090

-GPX5chr6

28500098

+
5CDS-intronENST00000405878ENST00000550775XRCC6chr22

42018090

+GPX5chr6

28500097

+
5CDS-intronENST00000405878ENST00000551639XRCC6chr22

42018090

+GPX5chr6

28497228

+
5CDS-intronENST00000405878ENST00000551639XRCC6chr22

42018090

-GPX5chr6

28500098

+
5CDS-intronENST00000405878ENST00000551639XRCC6chr22

42018090

+GPX5chr6

28500097

+
5UTR-3CDSENST00000428575ENST00000412168XRCC6chr22

42018090

+GPX5chr6

28497228

+
5UTR-3CDSENST00000428575ENST00000412168XRCC6chr22

42018090

-GPX5chr6

28500098

+
5UTR-3CDSENST00000428575ENST00000412168XRCC6chr22

42018090

+GPX5chr6

28500097

+
5UTR-3CDSENST00000428575ENST00000469384XRCC6chr22

42018090

+GPX5chr6

28497228

+
5UTR-3CDSENST00000428575ENST00000469384XRCC6chr22

42018090

-GPX5chr6

28500098

+
5UTR-3CDSENST00000428575ENST00000469384XRCC6chr22

42018090

+GPX5chr6

28500097

+
5UTR-3UTRENST00000428575ENST00000442674XRCC6chr22

42018090

+GPX5chr6

28497228

+
5UTR-3UTRENST00000428575ENST00000442674XRCC6chr22

42018090

-GPX5chr6

28500098

+
5UTR-3UTRENST00000428575ENST00000442674XRCC6chr22

42018090

+GPX5chr6

28500097

+
5UTR-intronENST00000428575ENST00000550775XRCC6chr22

42018090

+GPX5chr6

28497228

+
5UTR-intronENST00000428575ENST00000550775XRCC6chr22

42018090

-GPX5chr6

28500098

+
5UTR-intronENST00000428575ENST00000550775XRCC6chr22

42018090

+GPX5chr6

28500097

+
5UTR-intronENST00000428575ENST00000551639XRCC6chr22

42018090

+GPX5chr6

28497228

+
5UTR-intronENST00000428575ENST00000551639XRCC6chr22

42018090

-GPX5chr6

28500098

+
5UTR-intronENST00000428575ENST00000551639XRCC6chr22

42018090

+GPX5chr6

28500097

+
Frame-shiftENST00000359308ENST00000412168XRCC6chr22

42018090

+GPX5chr6

28497228

+
Frame-shiftENST00000359308ENST00000412168XRCC6chr22

42018090

-GPX5chr6

28500098

+
Frame-shiftENST00000359308ENST00000412168XRCC6chr22

42018090

+GPX5chr6

28500097

+
Frame-shiftENST00000359308ENST00000469384XRCC6chr22

42018090

+GPX5chr6

28497228

+
Frame-shiftENST00000360079ENST00000412168XRCC6chr22

42018090

+GPX5chr6

28497228

+
Frame-shiftENST00000360079ENST00000412168XRCC6chr22

42018090

-GPX5chr6

28500098

+
Frame-shiftENST00000360079ENST00000412168XRCC6chr22

42018090

+GPX5chr6

28500097

+
Frame-shiftENST00000360079ENST00000469384XRCC6chr22

42018090

+GPX5chr6

28497228

+
Frame-shiftENST00000402580ENST00000412168XRCC6chr22

42018090

+GPX5chr6

28497228

+
Frame-shiftENST00000402580ENST00000412168XRCC6chr22

42018090

-GPX5chr6

28500098

+
Frame-shiftENST00000402580ENST00000412168XRCC6chr22

42018090

+GPX5chr6

28500097

+
Frame-shiftENST00000402580ENST00000469384XRCC6chr22

42018090

+GPX5chr6

28497228

+
Frame-shiftENST00000405506ENST00000412168XRCC6chr22

42018090

-GPX5chr6

28500098

+
Frame-shiftENST00000405506ENST00000412168XRCC6chr22

42018090

+GPX5chr6

28500097

+
Frame-shiftENST00000405506ENST00000469384XRCC6chr22

42018090

-GPX5chr6

28500098

+
Frame-shiftENST00000405506ENST00000469384XRCC6chr22

42018090

+GPX5chr6

28500097

+
Frame-shiftENST00000405878ENST00000412168XRCC6chr22

42018090

+GPX5chr6

28497228

+
Frame-shiftENST00000405878ENST00000412168XRCC6chr22

42018090

-GPX5chr6

28500098

+
Frame-shiftENST00000405878ENST00000412168XRCC6chr22

42018090

+GPX5chr6

28500097

+
Frame-shiftENST00000405878ENST00000469384XRCC6chr22

42018090

+GPX5chr6

28497228

+
In-frameENST00000359308ENST00000469384XRCC6chr22

42018090

-GPX5chr6

28500098

+
In-frameENST00000359308ENST00000469384XRCC6chr22

42018090

+GPX5chr6

28500097

+
In-frameENST00000360079ENST00000469384XRCC6chr22

42018090

-GPX5chr6

28500098

+
In-frameENST00000360079ENST00000469384XRCC6chr22

42018090

+GPX5chr6

28500097

+
In-frameENST00000402580ENST00000469384XRCC6chr22

42018090

-GPX5chr6

28500098

+
In-frameENST00000402580ENST00000469384XRCC6chr22

42018090

+GPX5chr6

28500097

+
In-frameENST00000405506ENST00000412168XRCC6chr22

42018090

+GPX5chr6

28497228

+
In-frameENST00000405506ENST00000469384XRCC6chr22

42018090

+GPX5chr6

28497228

+
In-frameENST00000405878ENST00000469384XRCC6chr22

42018090

-GPX5chr6

28500098

+
In-frameENST00000405878ENST00000469384XRCC6chr22

42018090

+GPX5chr6

28500097

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000405506XRCC6chr2242018090+ENST00000412168GPX5chr628497228+146810459682207
ENST00000405506XRCC6chr2242018090+ENST00000469384GPX5chr628497228+443104271290
ENST00000360079XRCC6chr2242018090+ENST00000469384GPX5chr628500097+509324243181
ENST00000402580XRCC6chr2242018090+ENST00000469384GPX5chr628500097+3331483198677
ENST00000359308XRCC6chr2242018090+ENST00000469384GPX5chr628500097+9227374790160
ENST00000405878XRCC6chr2242018090+ENST00000469384GPX5chr628500097+41322839916677
ENST00000360079XRCC6chr2242018090-ENST00000469384GPX5chr628500098+509324243181
ENST00000402580XRCC6chr2242018090-ENST00000469384GPX5chr628500098+3331483198677
ENST00000359308XRCC6chr2242018090-ENST00000469384GPX5chr628500098+9227374790160
ENST00000405878XRCC6chr2242018090-ENST00000469384GPX5chr628500098+41322839916677

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000405506ENST00000412168XRCC6chr2242018090+GPX5chr628497228+0.002181510.99781847
ENST00000405506ENST00000469384XRCC6chr2242018090+GPX5chr628497228+0.052554720.94744533
ENST00000360079ENST00000469384XRCC6chr2242018090+GPX5chr628500097+0.133842330.86615765
ENST00000402580ENST00000469384XRCC6chr2242018090+GPX5chr628500097+0.227803950.77219605
ENST00000359308ENST00000469384XRCC6chr2242018090+GPX5chr628500097+0.276534260.7234657
ENST00000405878ENST00000469384XRCC6chr2242018090+GPX5chr628500097+0.11978950.8802105
ENST00000360079ENST00000469384XRCC6chr2242018090-GPX5chr628500098+0.133842330.86615765
ENST00000402580ENST00000469384XRCC6chr2242018090-GPX5chr628500098+0.227803950.77219605
ENST00000359308ENST00000469384XRCC6chr2242018090-GPX5chr628500098+0.276534260.7234657
ENST00000405878ENST00000469384XRCC6chr2242018090-GPX5chr628500098+0.11978950.8802105

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Fusion Genomic Features for XRCC6-GPX5


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
XRCC6chr2242018090+GPX5chr628500097+0.204852940.79514706
XRCC6chr2242018090+GPX5chr628497227+1.43E-050.9999857
XRCC6chr2242018090+GPX5chr628500097+0.204852940.79514706
XRCC6chr2242018090+GPX5chr628497227+1.43E-050.9999857

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for XRCC6-GPX5


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr22:42018090/chr6:28497228)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneXRCC6chr22:42018090chr6:28497228ENST00000359308+11211_2927610.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneXRCC6chr22:42018090chr6:28497228ENST00000360079+21311_2927610.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneXRCC6chr22:42018090chr6:28497228ENST00000405878+21311_2927610.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneXRCC6chr22:42018090chr6:28500097ENST00000359308+11211_2927610.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneXRCC6chr22:42018090chr6:28500097ENST00000360079+21311_2927610.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneXRCC6chr22:42018090chr6:28500097ENST00000405878+21311_2927610.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneXRCC6chr22:42018090chr6:28500098ENST00000359308-11211_2927610.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneXRCC6chr22:42018090chr6:28500098ENST00000360079-21311_2927610.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneXRCC6chr22:42018090chr6:28500098ENST00000405878-21311_2927610.0Compositional biasNote=Asp/Glu-rich (acidic)

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneXRCC6chr22:42018090chr6:28497228ENST00000359308+1122_6127610.0Compositional biasNote=Ser-rich (potentially targets for phosphorylation)
HgeneXRCC6chr22:42018090chr6:28497228ENST00000359308+112330_34227610.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneXRCC6chr22:42018090chr6:28497228ENST00000360079+2132_6127610.0Compositional biasNote=Ser-rich (potentially targets for phosphorylation)
HgeneXRCC6chr22:42018090chr6:28497228ENST00000360079+213330_34227610.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneXRCC6chr22:42018090chr6:28497228ENST00000405878+2132_6127610.0Compositional biasNote=Ser-rich (potentially targets for phosphorylation)
HgeneXRCC6chr22:42018090chr6:28497228ENST00000405878+213330_34227610.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneXRCC6chr22:42018090chr6:28500097ENST00000359308+1122_6127610.0Compositional biasNote=Ser-rich (potentially targets for phosphorylation)
HgeneXRCC6chr22:42018090chr6:28500097ENST00000359308+112330_34227610.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneXRCC6chr22:42018090chr6:28500097ENST00000360079+2132_6127610.0Compositional biasNote=Ser-rich (potentially targets for phosphorylation)
HgeneXRCC6chr22:42018090chr6:28500097ENST00000360079+213330_34227610.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneXRCC6chr22:42018090chr6:28500097ENST00000405878+2132_6127610.0Compositional biasNote=Ser-rich (potentially targets for phosphorylation)
HgeneXRCC6chr22:42018090chr6:28500097ENST00000405878+213330_34227610.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneXRCC6chr22:42018090chr6:28500098ENST00000359308-1122_6127610.0Compositional biasNote=Ser-rich (potentially targets for phosphorylation)
HgeneXRCC6chr22:42018090chr6:28500098ENST00000359308-112330_34227610.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneXRCC6chr22:42018090chr6:28500098ENST00000360079-2132_6127610.0Compositional biasNote=Ser-rich (potentially targets for phosphorylation)
HgeneXRCC6chr22:42018090chr6:28500098ENST00000360079-213330_34227610.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneXRCC6chr22:42018090chr6:28500098ENST00000405878-2132_6127610.0Compositional biasNote=Ser-rich (potentially targets for phosphorylation)
HgeneXRCC6chr22:42018090chr6:28500098ENST00000405878-213330_34227610.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneXRCC6chr22:42018090chr6:28497228ENST00000359308+112261_46827610.0DomainNote=Ku
HgeneXRCC6chr22:42018090chr6:28497228ENST00000359308+112573_60727610.0DomainSAP
HgeneXRCC6chr22:42018090chr6:28497228ENST00000360079+213261_46827610.0DomainNote=Ku
HgeneXRCC6chr22:42018090chr6:28497228ENST00000360079+213573_60727610.0DomainSAP
HgeneXRCC6chr22:42018090chr6:28497228ENST00000405878+213261_46827610.0DomainNote=Ku
HgeneXRCC6chr22:42018090chr6:28497228ENST00000405878+213573_60727610.0DomainSAP
HgeneXRCC6chr22:42018090chr6:28500097ENST00000359308+112261_46827610.0DomainNote=Ku
HgeneXRCC6chr22:42018090chr6:28500097ENST00000359308+112573_60727610.0DomainSAP
HgeneXRCC6chr22:42018090chr6:28500097ENST00000360079+213261_46827610.0DomainNote=Ku
HgeneXRCC6chr22:42018090chr6:28500097ENST00000360079+213573_60727610.0DomainSAP
HgeneXRCC6chr22:42018090chr6:28500097ENST00000405878+213261_46827610.0DomainNote=Ku
HgeneXRCC6chr22:42018090chr6:28500097ENST00000405878+213573_60727610.0DomainSAP
HgeneXRCC6chr22:42018090chr6:28500098ENST00000359308-112261_46827610.0DomainNote=Ku
HgeneXRCC6chr22:42018090chr6:28500098ENST00000359308-112573_60727610.0DomainSAP
HgeneXRCC6chr22:42018090chr6:28500098ENST00000360079-213261_46827610.0DomainNote=Ku
HgeneXRCC6chr22:42018090chr6:28500098ENST00000360079-213573_60727610.0DomainSAP
HgeneXRCC6chr22:42018090chr6:28500098ENST00000405878-213261_46827610.0DomainNote=Ku
HgeneXRCC6chr22:42018090chr6:28500098ENST00000405878-213573_60727610.0DomainSAP


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Fusion Gene Sequence for XRCC6-GPX5


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>99780_99780_1_XRCC6-GPX5_XRCC6_chr22_42018090_ENST00000359308_GPX5_chr6_28500097_ENST00000469384_length(transcript)=922nt_BP=737nt
GCGGGCCGTTATCCATTTGTGTTGTTCGCCAGCTAGGCCTGGCCTCGTCCCGCTTCGCTCGGTCGGTCTCGCGCGCCCCCATAGCCTTGC
TAGAGGGTTAGCGTTAGCCTTAAGTGTGCGAATCCGAGGAGCAGCGACAGACTCGAGACCACGCTCCTTCCTCGGGAAGGAGGCGGCACC
TCGCGTTTGAGGCCCGCCTGCGTTTGAGGCCCGCCTGCGCTTGCGGCCCGCCTGCGCTTGAGGCCTGTCTGCGTTTGAGATCTCATTGGG
CGTGATTGAGGAATTTGGGGAGGTTTTTGGGCGGTATTGAGGACGAGGGGGTCCGTTAGTCAGCATAGAATCCTGGAGCGGGAATCCCTC
ACCGTCTAAATGGCGTCGGGGGCGGGACCTCCGGGATCTGGCTTCCGCGGGCCGCCGCCGGCCCTGAAACGTGAGGGATAGCTGAGATGA
GGCAGCTACTGGGATGGCCCCCATGCGCATTTACATGCAGTCCGACTGCCGAGCTTTCGAGGCAGCAGGATTTACCGTCCACATTCCTCA
CTACTAACCAAGCTTTTAGAACAGATCTCACAAGAACCTAGAGGTCGGTATTTTTTCGATTTAAATTTGCCTGTTACTGACGTTAACGTC
TTTCGCCTAGTGAGCAGTAGCCAACATGTCAGGGTGGGAGTCATATTACAAAACCGAGGGCGATGAAGAAGCAGAGGAAGAACAAGAAGA
GAACCTTGAAGCAAGTGGTATGTCCGTCCAGGGGGAGGATTTGTACCTAGTTTCCAGCTTTTTGAGAAAGGGGATGTGAATGGTGAAAAA
GAACAGAAAGTCTTCAGTTTCTTGAAGCACTCCTGTCCTCATCCCTCTGAGATTTTGGGCACATTCAAATCTATATCCTGGGACCCTGTA

>99780_99780_1_XRCC6-GPX5_XRCC6_chr22_42018090_ENST00000359308_GPX5_chr6_28500097_ENST00000469384_length(amino acids)=160AA_BP=
MRMGAIPVAASSQLSLTFQGRRRPAEARSRRSRPRRHLDGEGFPLQDSMLTNGPPRPQYRPKTSPNSSITPNEISNADRPQAQAGRKRRR

--------------------------------------------------------------
>99780_99780_2_XRCC6-GPX5_XRCC6_chr22_42018090_ENST00000359308_GPX5_chr6_28500098_ENST00000469384_length(transcript)=922nt_BP=737nt
GCGGGCCGTTATCCATTTGTGTTGTTCGCCAGCTAGGCCTGGCCTCGTCCCGCTTCGCTCGGTCGGTCTCGCGCGCCCCCATAGCCTTGC
TAGAGGGTTAGCGTTAGCCTTAAGTGTGCGAATCCGAGGAGCAGCGACAGACTCGAGACCACGCTCCTTCCTCGGGAAGGAGGCGGCACC
TCGCGTTTGAGGCCCGCCTGCGTTTGAGGCCCGCCTGCGCTTGCGGCCCGCCTGCGCTTGAGGCCTGTCTGCGTTTGAGATCTCATTGGG
CGTGATTGAGGAATTTGGGGAGGTTTTTGGGCGGTATTGAGGACGAGGGGGTCCGTTAGTCAGCATAGAATCCTGGAGCGGGAATCCCTC
ACCGTCTAAATGGCGTCGGGGGCGGGACCTCCGGGATCTGGCTTCCGCGGGCCGCCGCCGGCCCTGAAACGTGAGGGATAGCTGAGATGA
GGCAGCTACTGGGATGGCCCCCATGCGCATTTACATGCAGTCCGACTGCCGAGCTTTCGAGGCAGCAGGATTTACCGTCCACATTCCTCA
CTACTAACCAAGCTTTTAGAACAGATCTCACAAGAACCTAGAGGTCGGTATTTTTTCGATTTAAATTTGCCTGTTACTGACGTTAACGTC
TTTCGCCTAGTGAGCAGTAGCCAACATGTCAGGGTGGGAGTCATATTACAAAACCGAGGGCGATGAAGAAGCAGAGGAAGAACAAGAAGA
GAACCTTGAAGCAAGTGGTATGTCCGTCCAGGGGGAGGATTTGTACCTAGTTTCCAGCTTTTTGAGAAAGGGGATGTGAATGGTGAAAAA
GAACAGAAAGTCTTCAGTTTCTTGAAGCACTCCTGTCCTCATCCCTCTGAGATTTTGGGCACATTCAAATCTATATCCTGGGACCCTGTA

>99780_99780_2_XRCC6-GPX5_XRCC6_chr22_42018090_ENST00000359308_GPX5_chr6_28500098_ENST00000469384_length(amino acids)=160AA_BP=
MRMGAIPVAASSQLSLTFQGRRRPAEARSRRSRPRRHLDGEGFPLQDSMLTNGPPRPQYRPKTSPNSSITPNEISNADRPQAQAGRKRRR

--------------------------------------------------------------
>99780_99780_3_XRCC6-GPX5_XRCC6_chr22_42018090_ENST00000360079_GPX5_chr6_28500097_ENST00000469384_length(transcript)=509nt_BP=324nt
GTAGGAAGGGGCGGGGCTTTGCCGAAGGGGGCGGGGCTCTCGCTGATGGGTTGGCTTTCGTCAGGGACATAGGTAGAAGCTGGTTGGGGA
GTGTGCGTGCCAGCCTGACGCGATATAGTGCGCACATGCGTGATGACGTAGAGGGCGTTGATTGGGACCGAGTACAGGGCCCGCGCATGC
GTGGATTGTCGTCTTCTGTCCAAGTTGGTCGCTTCCCTGCGCCAAAGTGAGCAGTAGCCAACATGTCAGGGTGGGAGTCATATTACAAAA
CCGAGGGCGATGAAGAAGCAGAGGAAGAACAAGAAGAGAACCTTGAAGCAAGTGGTATGTCCGTCCAGGGGGAGGATTTGTACCTAGTTT
CCAGCTTTTTGAGAAAGGGGATGTGAATGGTGAAAAAGAACAGAAAGTCTTCAGTTTCTTGAAGCACTCCTGTCCTCATCCCTCTGAGAT

>99780_99780_3_XRCC6-GPX5_XRCC6_chr22_42018090_ENST00000360079_GPX5_chr6_28500097_ENST00000469384_length(amino acids)=81AA_BP=

--------------------------------------------------------------
>99780_99780_4_XRCC6-GPX5_XRCC6_chr22_42018090_ENST00000360079_GPX5_chr6_28500098_ENST00000469384_length(transcript)=509nt_BP=324nt
GTAGGAAGGGGCGGGGCTTTGCCGAAGGGGGCGGGGCTCTCGCTGATGGGTTGGCTTTCGTCAGGGACATAGGTAGAAGCTGGTTGGGGA
GTGTGCGTGCCAGCCTGACGCGATATAGTGCGCACATGCGTGATGACGTAGAGGGCGTTGATTGGGACCGAGTACAGGGCCCGCGCATGC
GTGGATTGTCGTCTTCTGTCCAAGTTGGTCGCTTCCCTGCGCCAAAGTGAGCAGTAGCCAACATGTCAGGGTGGGAGTCATATTACAAAA
CCGAGGGCGATGAAGAAGCAGAGGAAGAACAAGAAGAGAACCTTGAAGCAAGTGGTATGTCCGTCCAGGGGGAGGATTTGTACCTAGTTT
CCAGCTTTTTGAGAAAGGGGATGTGAATGGTGAAAAAGAACAGAAAGTCTTCAGTTTCTTGAAGCACTCCTGTCCTCATCCCTCTGAGAT

>99780_99780_4_XRCC6-GPX5_XRCC6_chr22_42018090_ENST00000360079_GPX5_chr6_28500098_ENST00000469384_length(amino acids)=81AA_BP=

--------------------------------------------------------------
>99780_99780_5_XRCC6-GPX5_XRCC6_chr22_42018090_ENST00000402580_GPX5_chr6_28500097_ENST00000469384_length(transcript)=333nt_BP=148nt
ATGCGTGGATTGTCGTCTTCTGTCCAAGTTGGTCGCTTCCCTGCGCCAAAGTGAGCAGTAGCCAACATGTCAGGGTGGGAGTCATATTAC
AAAACCGAGGGCGATGAAGAAGCAGAGGAAGAACAAGAAGAGAACCTTGAAGCAAGTGGTATGTCCGTCCAGGGGGAGGATTTGTACCTA
GTTTCCAGCTTTTTGAGAAAGGGGATGTGAATGGTGAAAAAGAACAGAAAGTCTTCAGTTTCTTGAAGCACTCCTGTCCTCATCCCTCTG

>99780_99780_5_XRCC6-GPX5_XRCC6_chr22_42018090_ENST00000402580_GPX5_chr6_28500097_ENST00000469384_length(amino acids)=77AA_BP=0

--------------------------------------------------------------
>99780_99780_6_XRCC6-GPX5_XRCC6_chr22_42018090_ENST00000402580_GPX5_chr6_28500098_ENST00000469384_length(transcript)=333nt_BP=148nt
ATGCGTGGATTGTCGTCTTCTGTCCAAGTTGGTCGCTTCCCTGCGCCAAAGTGAGCAGTAGCCAACATGTCAGGGTGGGAGTCATATTAC
AAAACCGAGGGCGATGAAGAAGCAGAGGAAGAACAAGAAGAGAACCTTGAAGCAAGTGGTATGTCCGTCCAGGGGGAGGATTTGTACCTA
GTTTCCAGCTTTTTGAGAAAGGGGATGTGAATGGTGAAAAAGAACAGAAAGTCTTCAGTTTCTTGAAGCACTCCTGTCCTCATCCCTCTG

>99780_99780_6_XRCC6-GPX5_XRCC6_chr22_42018090_ENST00000402580_GPX5_chr6_28500098_ENST00000469384_length(amino acids)=77AA_BP=0

--------------------------------------------------------------
>99780_99780_7_XRCC6-GPX5_XRCC6_chr22_42018090_ENST00000405506_GPX5_chr6_28497228_ENST00000412168_length(transcript)=1468nt_BP=104nt
CGCCTAGTGAGCAGTAGCCAACATGTCAGGGTGGGAGTCATATTACAAAACCGAGGGCGATGAAGAAGCAGAGGAAGAACAAGAAGAGAA
CCTTGAAGCAAGTGATGGATTGCCACAAAGACGAGAAAGGCACCATCTATGACTATGAGGCCATCGCACTTAATAAGAATGAATATGTTT
CCTTCAAGCAGTATGTGGGCAAGCACATCCTCTTCGTCAACGTGGCCACCTACTGTGGTCTGACAGCGCAATATCCTGAACTAAATGCAC
TCCAGGAGGAGCTGAAGCCCTATGGTCTAGTTGTGTTGGGCTTTCCCTGCAACCAATTTGGAAAGCAAGAACCAGGAGATAACAAAGAGA
TTCTTCCTGGGCTCAAGTATGTCCGTCCAGGGGGAGGATTTGTACCTAGTTTCCAGCTTTTTGAGAAAGGGGATGTGAATGGTGAAAAAG
AACAGAAAGTCTTCAGTTTCTTGAAGCACTCCTGTCCTCATCCCTCTGAGATTTTGGGCACATTCAAATCTATATCCTGGGACCCTGTAA
AGGTCCATGACATCCGTTGGAACTTTGAAAAGTTCCTGGTGGGGCCTGATGGAATCCCTGTCATGCGCTGGTCCCACCGGGCTACGGTCA
GCTCAGTCAAGACAGACATCCTGGCGTACTTGAAGCAATTCAAAACCAAATAGGAAGGTGGAGTTAAGGGCAGGAGCAACCCTACTTCTC
ACCTAATGACTTGCTCTCCCCACCCCTCCAAAAAAAAGGAATACCCATCTTCTCACCACACTCTCTTCCTGCATGGGCTCCACCTGAGTA
AATCACCGCCACATACTGCCAGAATTCCCACTCTCCACAAACTAGATTTATATTTGGAAGGCTACTGCTCTTTTGCCTCTCAAGAGTATG
TGGGTGAAGACTGAAACAAATGGAAACCTAAAATCCCCAGACCTCTGTTACAGGTTGAATCATTCATATCCACCAGAGGGAAATCATCCT
TCCACGACAATGGTTCAGTCGGCCATCACATCCTGAAGAACATTCCTAGACATTCTGACTCTTCCATCTCTCTCTACCCTGGAGGTGTAG
AAATAGCAATGGGGTCACAGTCACACAATTTAGGTTCCACTTCATAACATTTTTTGTCTCCTAGGACAAACGTGTATCATCAGTTTCCAA
CTGTTTTGGCTCAGTTTTCATCCATGACACCTCCCCCTACCAGCCATTCTCCTGTGGGAGCAAGAACATTGCTTCAAAAGAAGAGAGGGC
ATCTCCATGCTTGTGGGACCCAAAACCTATCTCTGGCCCTACAAAAGTTTTCCTAATTGTCTGATCTTTAGTGCATTCAGGTTATGGCAC
CTGGAGAGGAATGCCCTTTATCTTTTGAAGGATGGGATTTCCCATCTCAACCCTGGATTCCTCACCTTCAGAACGAGCCCTGCCACTGTC

>99780_99780_7_XRCC6-GPX5_XRCC6_chr22_42018090_ENST00000405506_GPX5_chr6_28497228_ENST00000412168_length(amino acids)=207AA_BP=15
MKKQRKNKKRTLKQVMDCHKDEKGTIYDYEAIALNKNEYVSFKQYVGKHILFVNVATYCGLTAQYPELNALQEELKPYGLVVLGFPCNQF
GKQEPGDNKEILPGLKYVRPGGGFVPSFQLFEKGDVNGEKEQKVFSFLKHSCPHPSEILGTFKSISWDPVKVHDIRWNFEKFLVGPDGIP

--------------------------------------------------------------
>99780_99780_8_XRCC6-GPX5_XRCC6_chr22_42018090_ENST00000405506_GPX5_chr6_28497228_ENST00000469384_length(transcript)=443nt_BP=104nt
CGCCTAGTGAGCAGTAGCCAACATGTCAGGGTGGGAGTCATATTACAAAACCGAGGGCGATGAAGAAGCAGAGGAAGAACAAGAAGAGAA
CCTTGAAGCAAGTGATGGATTGCCACAAAGACGAGAAAGGCACCATCTATGACTATGAGGCCATCGCACTTAATAAGAATGAATATGTTT
CCTTCAAGCAGTATGTGGGCAAGCACATCCTCTTCGTCAACGTGGCCACCTACTGTGGTCTGACAGCGCAATATCCTGGTATGTCCGTCC
AGGGGGAGGATTTGTACCTAGTTTCCAGCTTTTTGAGAAAGGGGATGTGAATGGTGAAAAAGAACAGAAAGTCTTCAGTTTCTTGAAGCA

>99780_99780_8_XRCC6-GPX5_XRCC6_chr22_42018090_ENST00000405506_GPX5_chr6_28497228_ENST00000469384_length(amino acids)=90AA_BP=4
MDGHTRILRCQTTVGGHVDEEDVLAHILLEGNIFILIKCDGLIVIDGAFLVFVAIHHLLQGSLLVLPLLLHRPRFCNMTPTLTCWLLLTR

--------------------------------------------------------------
>99780_99780_9_XRCC6-GPX5_XRCC6_chr22_42018090_ENST00000405878_GPX5_chr6_28500097_ENST00000469384_length(transcript)=413nt_BP=228nt
AAGTGTGCGAATCCGAGGAGCAGCGACAGACTCGAGACCACGCTCCTTCCTCGGGAAGGAGGCGGCACCTCGCGTTTGAGGCCCGCCTGC
GTTTGAGGCCCGCCTGCGCTTGCGGCCCGCCTGCGCTTGAGTGAGCAGTAGCCAACATGTCAGGGTGGGAGTCATATTACAAAACCGAGG
GCGATGAAGAAGCAGAGGAAGAACAAGAAGAGAACCTTGAAGCAAGTGGTATGTCCGTCCAGGGGGAGGATTTGTACCTAGTTTCCAGCT
TTTTGAGAAAGGGGATGTGAATGGTGAAAAAGAACAGAAAGTCTTCAGTTTCTTGAAGCACTCCTGTCCTCATCCCTCTGAGATTTTGGG

>99780_99780_9_XRCC6-GPX5_XRCC6_chr22_42018090_ENST00000405878_GPX5_chr6_28500097_ENST00000469384_length(amino acids)=77AA_BP=0

--------------------------------------------------------------
>99780_99780_10_XRCC6-GPX5_XRCC6_chr22_42018090_ENST00000405878_GPX5_chr6_28500098_ENST00000469384_length(transcript)=413nt_BP=228nt
AAGTGTGCGAATCCGAGGAGCAGCGACAGACTCGAGACCACGCTCCTTCCTCGGGAAGGAGGCGGCACCTCGCGTTTGAGGCCCGCCTGC
GTTTGAGGCCCGCCTGCGCTTGCGGCCCGCCTGCGCTTGAGTGAGCAGTAGCCAACATGTCAGGGTGGGAGTCATATTACAAAACCGAGG
GCGATGAAGAAGCAGAGGAAGAACAAGAAGAGAACCTTGAAGCAAGTGGTATGTCCGTCCAGGGGGAGGATTTGTACCTAGTTTCCAGCT
TTTTGAGAAAGGGGATGTGAATGGTGAAAAAGAACAGAAAGTCTTCAGTTTCTTGAAGCACTCCTGTCCTCATCCCTCTGAGATTTTGGG

>99780_99780_10_XRCC6-GPX5_XRCC6_chr22_42018090_ENST00000405878_GPX5_chr6_28500098_ENST00000469384_length(amino acids)=77AA_BP=0

--------------------------------------------------------------

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Fusion Gene PPI Analysis for XRCC6-GPX5


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneXRCC6chr22:42018090chr6:28497228ENST00000359308+112550_60927.333333333333332610.0DEAF1
HgeneXRCC6chr22:42018090chr6:28497228ENST00000360079+213550_60927.333333333333332610.0DEAF1
HgeneXRCC6chr22:42018090chr6:28497228ENST00000405878+213550_60927.333333333333332610.0DEAF1
HgeneXRCC6chr22:42018090chr6:28500097ENST00000359308+112550_60927.333333333333332610.0DEAF1
HgeneXRCC6chr22:42018090chr6:28500097ENST00000360079+213550_60927.333333333333332610.0DEAF1
HgeneXRCC6chr22:42018090chr6:28500097ENST00000405878+213550_60927.333333333333332610.0DEAF1
HgeneXRCC6chr22:42018090chr6:28500098ENST00000359308-112550_60927.333333333333332610.0DEAF1
HgeneXRCC6chr22:42018090chr6:28500098ENST00000360079-213550_60927.333333333333332610.0DEAF1
HgeneXRCC6chr22:42018090chr6:28500098ENST00000405878-213550_60927.333333333333332610.0DEAF1


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for XRCC6-GPX5


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for XRCC6-GPX5


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource