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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:XRCC6-L3MBTL2 (FusionGDB2 ID:99781)

Fusion Gene Summary for XRCC6-L3MBTL2

check button Fusion gene summary
Fusion gene informationFusion gene name: XRCC6-L3MBTL2
Fusion gene ID: 99781
HgeneTgene
Gene symbol

XRCC6

L3MBTL2

Gene ID

2547

83746

Gene nameX-ray repair cross complementing 6L3MBTL histone methyl-lysine binding protein 2
SynonymsCTC75|CTCBF|G22P1|KU70|ML8|TLAAH-l(3)mbt-l|L3MBT
Cytomap

22q13.2

22q13.2

Type of geneprotein-codingprotein-coding
DescriptionX-ray repair cross-complementing protein 65'-dRP lyase Ku705'-deoxyribose-5-phosphate lyase Ku7070 kDa subunit of Ku antigenATP-dependent DNA helicase 2 subunit 1ATP-dependent DNA helicase II, 70 kDa subunitCTC box binding factor 75 kDa subunitDNA lethal(3)malignant brain tumor-like protein 2H-l(3)mbt-like protein 2L(3)mbt-like protein 2L3MBTL2, polycomb repressive complex 1 subunitl(3)mbt-like 2
Modification date2020032920200313
UniProtAcc.

Q969R5

Ensembl transtripts involved in fusion geneENST00000359308, ENST00000360079, 
ENST00000402580, ENST00000405506, 
ENST00000405878, ENST00000428575, 
ENST00000489136, ENST00000216237, 
Fusion gene scores* DoF score12 X 10 X 8=9603 X 8 X 4=96
# samples 157
** MAII scorelog2(15/960*10)=-2.67807190511264
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(7/96*10)=-0.45567948377619
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: XRCC6 [Title/Abstract] AND L3MBTL2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointXRCC6(42054356)-L3MBTL2(41621798), # samples:2
Anticipated loss of major functional domain due to fusion event.XRCC6-L3MBTL2 seems lost the major protein functional domain in Tgene partner, which is a epigenetic factor due to the frame-shifted ORF.
XRCC6-L3MBTL2 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneXRCC6

GO:0002218

activation of innate immune response

28712728

HgeneXRCC6

GO:0045860

positive regulation of protein kinase activity

22504299

HgeneXRCC6

GO:0045893

positive regulation of transcription, DNA-templated

12145306

HgeneXRCC6

GO:0071480

cellular response to gamma radiation

26359349

HgeneXRCC6

GO:0097680

double-strand break repair via classical nonhomologous end joining

24095731


check buttonFusion gene breakpoints across XRCC6 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across L3MBTL2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-13-A5FT-01AXRCC6chr22

42054356

+L3MBTL2chr22

41621798

+
ChimerDB4OVTCGA-13-A5FT-01AXRCC6chr22

42054356

+L3MBTL2chr22

41622666

+
ChimerDB4OVTCGA-13-A5FTXRCC6chr22

42054356

+L3MBTL2chr22

41621797

+


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Fusion Gene ORF analysis for XRCC6-L3MBTL2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000359308ENST00000489136XRCC6chr22

42054356

+L3MBTL2chr22

41621798

+
5CDS-intronENST00000359308ENST00000489136XRCC6chr22

42054356

+L3MBTL2chr22

41622666

+
5CDS-intronENST00000359308ENST00000489136XRCC6chr22

42054356

+L3MBTL2chr22

41621797

+
5CDS-intronENST00000360079ENST00000489136XRCC6chr22

42054356

+L3MBTL2chr22

41621798

+
5CDS-intronENST00000360079ENST00000489136XRCC6chr22

42054356

+L3MBTL2chr22

41622666

+
5CDS-intronENST00000360079ENST00000489136XRCC6chr22

42054356

+L3MBTL2chr22

41621797

+
5CDS-intronENST00000402580ENST00000489136XRCC6chr22

42054356

+L3MBTL2chr22

41621798

+
5CDS-intronENST00000402580ENST00000489136XRCC6chr22

42054356

+L3MBTL2chr22

41622666

+
5CDS-intronENST00000402580ENST00000489136XRCC6chr22

42054356

+L3MBTL2chr22

41621797

+
5CDS-intronENST00000405506ENST00000489136XRCC6chr22

42054356

+L3MBTL2chr22

41621798

+
5CDS-intronENST00000405506ENST00000489136XRCC6chr22

42054356

+L3MBTL2chr22

41622666

+
5CDS-intronENST00000405506ENST00000489136XRCC6chr22

42054356

+L3MBTL2chr22

41621797

+
5CDS-intronENST00000405878ENST00000489136XRCC6chr22

42054356

+L3MBTL2chr22

41621798

+
5CDS-intronENST00000405878ENST00000489136XRCC6chr22

42054356

+L3MBTL2chr22

41622666

+
5CDS-intronENST00000405878ENST00000489136XRCC6chr22

42054356

+L3MBTL2chr22

41621797

+
5CDS-intronENST00000428575ENST00000489136XRCC6chr22

42054356

+L3MBTL2chr22

41621798

+
5CDS-intronENST00000428575ENST00000489136XRCC6chr22

42054356

+L3MBTL2chr22

41622666

+
5CDS-intronENST00000428575ENST00000489136XRCC6chr22

42054356

+L3MBTL2chr22

41621797

+
Frame-shiftENST00000359308ENST00000216237XRCC6chr22

42054356

+L3MBTL2chr22

41621798

+
Frame-shiftENST00000359308ENST00000216237XRCC6chr22

42054356

+L3MBTL2chr22

41621797

+
Frame-shiftENST00000360079ENST00000216237XRCC6chr22

42054356

+L3MBTL2chr22

41621798

+
Frame-shiftENST00000360079ENST00000216237XRCC6chr22

42054356

+L3MBTL2chr22

41621797

+
Frame-shiftENST00000402580ENST00000216237XRCC6chr22

42054356

+L3MBTL2chr22

41621798

+
Frame-shiftENST00000402580ENST00000216237XRCC6chr22

42054356

+L3MBTL2chr22

41621797

+
Frame-shiftENST00000405506ENST00000216237XRCC6chr22

42054356

+L3MBTL2chr22

41621798

+
Frame-shiftENST00000405506ENST00000216237XRCC6chr22

42054356

+L3MBTL2chr22

41621797

+
Frame-shiftENST00000405878ENST00000216237XRCC6chr22

42054356

+L3MBTL2chr22

41621798

+
Frame-shiftENST00000405878ENST00000216237XRCC6chr22

42054356

+L3MBTL2chr22

41621797

+
Frame-shiftENST00000428575ENST00000216237XRCC6chr22

42054356

+L3MBTL2chr22

41621798

+
Frame-shiftENST00000428575ENST00000216237XRCC6chr22

42054356

+L3MBTL2chr22

41621797

+
In-frameENST00000359308ENST00000216237XRCC6chr22

42054356

+L3MBTL2chr22

41622666

+
In-frameENST00000360079ENST00000216237XRCC6chr22

42054356

+L3MBTL2chr22

41622666

+
In-frameENST00000402580ENST00000216237XRCC6chr22

42054356

+L3MBTL2chr22

41622666

+
In-frameENST00000405506ENST00000216237XRCC6chr22

42054356

+L3MBTL2chr22

41622666

+
In-frameENST00000405878ENST00000216237XRCC6chr22

42054356

+L3MBTL2chr22

41622666

+
In-frameENST00000428575ENST00000216237XRCC6chr22

42054356

+L3MBTL2chr22

41622666

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000360079XRCC6chr2242054356+ENST00000216237L3MBTL2chr2241622666+339817642422377711
ENST00000402580XRCC6chr2242054356+ENST00000216237L3MBTL2chr2241622666+30991465662078670
ENST00000428575XRCC6chr2242054356+ENST00000216237L3MBTL2chr2241622666+30981464922077661
ENST00000359308XRCC6chr2242054356+ENST00000216237L3MBTL2chr2241622666+381121776552790711
ENST00000405878XRCC6chr2242054356+ENST00000216237L3MBTL2chr2241622666+330216681462281711
ENST00000405506XRCC6chr2242054356+ENST00000216237L3MBTL2chr2241622666+30651431592044661

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000360079ENST00000216237XRCC6chr2242054356+L3MBTL2chr2241622666+0.0066677720.9933322
ENST00000402580ENST00000216237XRCC6chr2242054356+L3MBTL2chr2241622666+0.006270640.99372935
ENST00000428575ENST00000216237XRCC6chr2242054356+L3MBTL2chr2241622666+0.0040445690.99595547
ENST00000359308ENST00000216237XRCC6chr2242054356+L3MBTL2chr2241622666+0.0075487810.99245125
ENST00000405878ENST00000216237XRCC6chr2242054356+L3MBTL2chr2241622666+0.0079457180.99205434
ENST00000405506ENST00000216237XRCC6chr2242054356+L3MBTL2chr2241622666+0.0043695270.9956305

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Fusion Genomic Features for XRCC6-L3MBTL2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
XRCC6chr2242054356+L3MBTL2chr2241622665+0.0003056170.99969447
XRCC6chr2242054356+L3MBTL2chr2241621797+3.31E-050.99996686
XRCC6chr2242054356+L3MBTL2chr2241621797+3.31E-050.99996686
XRCC6chr2242054356+L3MBTL2chr2241622665+0.0003056170.99969447
XRCC6chr2242054356+L3MBTL2chr2241621797+3.31E-050.99996686
XRCC6chr2242054356+L3MBTL2chr2241621797+3.31E-050.99996686

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for XRCC6-L3MBTL2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr22:42054356/chr22:41621798)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.L3MBTL2

Q969R5

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27'. {ECO:0000269|PubMed:19233876}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneXRCC6chr22:42054356chr22:41622666ENST00000359308+101211_29507610.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneXRCC6chr22:42054356chr22:41622666ENST00000359308+10122_61507610.0Compositional biasNote=Ser-rich (potentially targets for phosphorylation)
HgeneXRCC6chr22:42054356chr22:41622666ENST00000359308+1012330_342507610.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneXRCC6chr22:42054356chr22:41622666ENST00000360079+111311_29507610.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneXRCC6chr22:42054356chr22:41622666ENST00000360079+11132_61507610.0Compositional biasNote=Ser-rich (potentially targets for phosphorylation)
HgeneXRCC6chr22:42054356chr22:41622666ENST00000360079+1113330_342507610.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneXRCC6chr22:42054356chr22:41622666ENST00000405878+111311_29507610.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneXRCC6chr22:42054356chr22:41622666ENST00000405878+11132_61507610.0Compositional biasNote=Ser-rich (potentially targets for phosphorylation)
HgeneXRCC6chr22:42054356chr22:41622666ENST00000405878+1113330_342507610.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneXRCC6chr22:42054356chr22:41622666ENST00000359308+1012261_468507610.0DomainNote=Ku
HgeneXRCC6chr22:42054356chr22:41622666ENST00000360079+1113261_468507610.0DomainNote=Ku
HgeneXRCC6chr22:42054356chr22:41622666ENST00000405878+1113261_468507610.0DomainNote=Ku
TgeneL3MBTL2chr22:42054356chr22:41622666ENST000002162371117620_624501706.0Compositional biasNote=Poly-Lys
TgeneL3MBTL2chr22:42054356chr22:41622666ENST000002162371117508_604501706.0RepeatNote=MBT 4

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneXRCC6chr22:42054356chr22:41622666ENST00000359308+1012573_607507610.0DomainSAP
HgeneXRCC6chr22:42054356chr22:41622666ENST00000360079+1113573_607507610.0DomainSAP
HgeneXRCC6chr22:42054356chr22:41622666ENST00000405878+1113573_607507610.0DomainSAP
TgeneL3MBTL2chr22:42054356chr22:41622666ENST00000216237111717_20501706.0Compositional biasNote=Poly-Glu
TgeneL3MBTL2chr22:42054356chr22:41622666ENST000002162371117179_283501706.0RepeatNote=MBT 1
TgeneL3MBTL2chr22:42054356chr22:41622666ENST000002162371117291_391501706.0RepeatNote=MBT 2
TgeneL3MBTL2chr22:42054356chr22:41622666ENST000002162371117397_500501706.0RepeatNote=MBT 3
TgeneL3MBTL2chr22:42054356chr22:41622666ENST00000216237111781_116501706.0Zinc fingerFCS-type


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Fusion Gene Sequence for XRCC6-L3MBTL2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>99781_99781_1_XRCC6-L3MBTL2_XRCC6_chr22_42054356_ENST00000359308_L3MBTL2_chr22_41622666_ENST00000216237_length(transcript)=3811nt_BP=2177nt
GCGGGCCGTTATCCATTTGTGTTGTTCGCCAGCTAGGCCTGGCCTCGTCCCGCTTCGCTCGGTCGGTCTCGCGCGCCCCCATAGCCTTGC
TAGAGGGTTAGCGTTAGCCTTAAGTGTGCGAATCCGAGGAGCAGCGACAGACTCGAGACCACGCTCCTTCCTCGGGAAGGAGGCGGCACC
TCGCGTTTGAGGCCCGCCTGCGTTTGAGGCCCGCCTGCGCTTGCGGCCCGCCTGCGCTTGAGGCCTGTCTGCGTTTGAGATCTCATTGGG
CGTGATTGAGGAATTTGGGGAGGTTTTTGGGCGGTATTGAGGACGAGGGGGTCCGTTAGTCAGCATAGAATCCTGGAGCGGGAATCCCTC
ACCGTCTAAATGGCGTCGGGGGCGGGACCTCCGGGATCTGGCTTCCGCGGGCCGCCGCCGGCCCTGAAACGTGAGGGATAGCTGAGATGA
GGCAGCTACTGGGATGGCCCCCATGCGCATTTACATGCAGTCCGACTGCCGAGCTTTCGAGGCAGCAGGATTTACCGTCCACATTCCTCA
CTACTAACCAAGCTTTTAGAACAGATCTCACAAGAACCTAGAGGTCGGTATTTTTTCGATTTAAATTTGCCTGTTACTGACGTTAACGTC
TTTCGCCTAGTGAGCAGTAGCCAACATGTCAGGGTGGGAGTCATATTACAAAACCGAGGGCGATGAAGAAGCAGAGGAAGAACAAGAAGA
GAACCTTGAAGCAAGTGGAGACTATAAATATTCAGGAAGAGATAGTTTGATTTTTTTGGTTGATGCCTCCAAGGCTATGTTTGAATCTCA
GAGTGAAGATGAGTTGACACCTTTTGACATGAGCATCCAGTGTATCCAAAGTGTGTACATCAGTAAGATCATAAGCAGTGATCGAGATCT
CTTGGCTGTGGTGTTCTATGGTACCGAGAAAGACAAAAATTCAGTGAATTTTAAAAATATTTACGTCTTACAGGAGCTGGATAATCCAGG
TGCAAAACGAATTCTAGAGCTTGACCAGTTTAAGGGGCAGCAGGGACAAAAACGTTTCCAAGACATGATGGGCCACGGATCTGACTACTC
ACTCAGTGAAGTGCTGTGGGTCTGTGCCAACCTCTTTAGTGATGTCCAATTCAAGATGAGTCATAAGAGGATCATGCTGTTCACCAATGA
AGACAACCCCCATGGCAATGACAGTGCCAAAGCCAGCCGGGCCAGGACCAAAGCCGGTGATCTCCGAGATACAGGCATCTTCCTTGACTT
GATGCACCTGAAGAAACCTGGGGGCTTTGACATATCCTTGTTCTACAGAGATATCATCAGCATAGCAGAGGATGAGGACCTCAGGGTTCA
CTTTGAGGAATCCAGCAAGCTAGAAGACCTGTTGCGGAAGGTTCGCGCCAAGGAGACCAGGAAGCGAGCACTCAGCAGGTTAAAGCTGAA
GCTCAACAAAGATATAGTGATCTCTGTGGGCATTTATAATCTGGTCCAGAAGGCTCTCAAGCCTCCTCCAATAAAGCTCTATCGGGAAAC
AAATGAACCAGTGAAAACCAAGACCCGGACCTTTAATACAAGTACAGGCGGTTTGCTTCTGCCTAGCGATACCAAGAGGTCTCAGATCTA
TGGGAGTCGTCAGATTATACTGGAGAAAGAGGAAACAGAAGAGCTAAAACGGTTTGATGATCCAGGTTTGATGCTCATGGGTTTCAAGCC
GTTGGTACTGCTGAAGAAACACCATTACCTGAGGCCCTCCCTGTTCGTGTACCCAGAGGAGTCGCTGGTGATTGGGAGCTCAACCCTGTT
CAGTGCTCTGCTCATCAAGTGTCTGGAGAAGGAGGTTGCAGCATTGTGCAGATACACACCCCGCAGGAACATCCCTCCTTATTTTGTGGC
TTTGGTGCCACAGGAAGAAGAGTTGGATGACCAGAAAATTCAGGTGACTCCTCCAGGCTTCCAGCTGGTCTTTTTACCCTTTGCTGATGA
TAAAAGGAAGATGCCCTTTACTGAAAAAATCATGGCAACTCCAGAGCAGGTGGGCAAGATGAAGGCTATCGTTGAGAAGCTTCGCTTCAC
ATACAGAAGTGACAGCTTTGAGAACCCCGTGCTGCAGCAGCACTTCAGGAACCTGGAGGCCTTGGCCTTGGATTTGATGGAGCCGGAACA
AGCAGTGGACCTGACATGTTATGAGGCACAGACTTTCAACTGGGAGAACTACTTGGAGAAGACCAAGTCGAAAGCCGCTCCATCGAGACT
CTTTAACATGGATTGCCCAAACCATGGCTTCAAGGTGGGCATGAAGCTGGAGGCCGTGGACCTGATGGAGCCCCGGCTCATCTGTGTGGC
CACGGTGAAACGAGTGGTGCATCGGCTCCTCAGCATCCACTTTGACGGCTGGGACAGCGAGTACGACCAGTGGGTGGACTGCGAGTCCCC
AGACATCTACCCCGTCGGCTGGTGTGAGCTCACCGGCTACCAGCTCCAGCCTCCTGTGGCCGCAGAACCGGCCACACCGCTGAAGGCCAA
AGAGGCCACAAAGAAGAAAAAGAAACAGTTTGGGAAGAAAAGGAAAAGAATCCCGCCCACTAAGACGCGACCCCTCAGACAGGGGTCCAA
GAAGCCCCTGCTGGAGGACGACCCTCAGGGTGCCAGGAAGATCTCGTCGGAGCCTGTTCCTGGCGAGATCATTGCTGTGCGTGTGAAGGA
AGAGCATCTAGACGTGGCCTCGCCCGACAAGGCTTCAAGTCCAGAGCTGCCTGTCTCCGTCGAGAACATCAAGCAGGAAACAGACGACTG
AGCCTTCCTGCCTCCAGCCTGGCTTCTAGCTGGAAGCCAGCCCAGCGTTTCTCTACCACCACCACCATGCCTCCACCTGACTTTGGCTTG
GAGACTGATCCTCTCTGTGTAAATTCTGCCCGGTGCTGTGAAGGCTGGACGGTGGAGGACCTGCTGGGGTCTCCTGGGACCCGCCTGTTG
CTTCTGCCCTCCCCTGTGGAAAGGTCTATATGACGGGCCGCCTGAGGCCCCAGAACTCGTCTGTGAACCACCTTTTCCAGCCAGAGTTCC
CAAAGCTGGAACGCTAGCTGCCTGCTCTTCCTTAAGATGGCCTCCCCCCGACCCGCCACGGCCCTCAGTTGCCAGGGATGGGGCCACCAC
TGTCACACTGTGGAATACAAGACAGTGAACTCTGTCTGCCTGAACGAGCCATGTAAATTAAGTTCTAGAGCAGCTCTCTGAGCAGGATAA
GGTCCCCTGACAGTGAGTTGTGTGGTGGGGGCAGCCTCTGCCTCAAAAATTCACCAAGCAGAATGCCTCTCAGCCTCATGTGTTGGTCCT
CTGCTCCTCCTAGCTCCCCAGGGATGTTGGGGACCCAGCTTGTCTCGGCAGCTAAGAAGCAGTGACCAGGATGTGGATTTTGGCGACCTG
TGTGGTGGCCTTGAGCTGCTTTCTGTGTTTGTGAGGACTGACTCCCATTTCCTAAAGGAAATGCCCCCGGGGAGGACATTGGGAGGAAGA
TGGCCTGAGTGTGCACTTTGGCTCTGCTACCTGCTCCTGAAGCCCCGCTAAAAATAATTCATCCAAGATTCCTTTGTAGTTAAAGGGTCC
AGTTCTGACTGGAGCCTCTAGAGAGCTGGGCTTGTATGTTCTTTTGGCCTTTTGTTCCTACCTAAATGAAGAAACCATGCCTGGAGGGGC
CGTGAACACAGAACCCTCAAGACAAGGATGACAGAGCTGGAGGACACATCTAGCTGCCATTGCAACCTCACTGGGCTCCCCAGACTCTGT

>99781_99781_1_XRCC6-L3MBTL2_XRCC6_chr22_42054356_ENST00000359308_L3MBTL2_chr22_41622666_ENST00000216237_length(amino acids)=711AA_BP=508
MSGWESYYKTEGDEEAEEEQEENLEASGDYKYSGRDSLIFLVDASKAMFESQSEDELTPFDMSIQCIQSVYISKIISSDRDLLAVVFYGT
EKDKNSVNFKNIYVLQELDNPGAKRILELDQFKGQQGQKRFQDMMGHGSDYSLSEVLWVCANLFSDVQFKMSHKRIMLFTNEDNPHGNDS
AKASRARTKAGDLRDTGIFLDLMHLKKPGGFDISLFYRDIISIAEDEDLRVHFEESSKLEDLLRKVRAKETRKRALSRLKLKLNKDIVIS
VGIYNLVQKALKPPPIKLYRETNEPVKTKTRTFNTSTGGLLLPSDTKRSQIYGSRQIILEKEETEELKRFDDPGLMLMGFKPLVLLKKHH
YLRPSLFVYPEESLVIGSSTLFSALLIKCLEKEVAALCRYTPRRNIPPYFVALVPQEEELDDQKIQVTPPGFQLVFLPFADDKRKMPFTE
KIMATPEQVGKMKAIVEKLRFTYRSDSFENPVLQQHFRNLEALALDLMEPEQAVDLTCYEAQTFNWENYLEKTKSKAAPSRLFNMDCPNH
GFKVGMKLEAVDLMEPRLICVATVKRVVHRLLSIHFDGWDSEYDQWVDCESPDIYPVGWCELTGYQLQPPVAAEPATPLKAKEATKKKKK

--------------------------------------------------------------
>99781_99781_2_XRCC6-L3MBTL2_XRCC6_chr22_42054356_ENST00000360079_L3MBTL2_chr22_41622666_ENST00000216237_length(transcript)=3398nt_BP=1764nt
GTAGGAAGGGGCGGGGCTTTGCCGAAGGGGGCGGGGCTCTCGCTGATGGGTTGGCTTTCGTCAGGGACATAGGTAGAAGCTGGTTGGGGA
GTGTGCGTGCCAGCCTGACGCGATATAGTGCGCACATGCGTGATGACGTAGAGGGCGTTGATTGGGACCGAGTACAGGGCCCGCGCATGC
GTGGATTGTCGTCTTCTGTCCAAGTTGGTCGCTTCCCTGCGCCAAAGTGAGCAGTAGCCAACATGTCAGGGTGGGAGTCATATTACAAAA
CCGAGGGCGATGAAGAAGCAGAGGAAGAACAAGAAGAGAACCTTGAAGCAAGTGGAGACTATAAATATTCAGGAAGAGATAGTTTGATTT
TTTTGGTTGATGCCTCCAAGGCTATGTTTGAATCTCAGAGTGAAGATGAGTTGACACCTTTTGACATGAGCATCCAGTGTATCCAAAGTG
TGTACATCAGTAAGATCATAAGCAGTGATCGAGATCTCTTGGCTGTGGTGTTCTATGGTACCGAGAAAGACAAAAATTCAGTGAATTTTA
AAAATATTTACGTCTTACAGGAGCTGGATAATCCAGGTGCAAAACGAATTCTAGAGCTTGACCAGTTTAAGGGGCAGCAGGGACAAAAAC
GTTTCCAAGACATGATGGGCCACGGATCTGACTACTCACTCAGTGAAGTGCTGTGGGTCTGTGCCAACCTCTTTAGTGATGTCCAATTCA
AGATGAGTCATAAGAGGATCATGCTGTTCACCAATGAAGACAACCCCCATGGCAATGACAGTGCCAAAGCCAGCCGGGCCAGGACCAAAG
CCGGTGATCTCCGAGATACAGGCATCTTCCTTGACTTGATGCACCTGAAGAAACCTGGGGGCTTTGACATATCCTTGTTCTACAGAGATA
TCATCAGCATAGCAGAGGATGAGGACCTCAGGGTTCACTTTGAGGAATCCAGCAAGCTAGAAGACCTGTTGCGGAAGGTTCGCGCCAAGG
AGACCAGGAAGCGAGCACTCAGCAGGTTAAAGCTGAAGCTCAACAAAGATATAGTGATCTCTGTGGGCATTTATAATCTGGTCCAGAAGG
CTCTCAAGCCTCCTCCAATAAAGCTCTATCGGGAAACAAATGAACCAGTGAAAACCAAGACCCGGACCTTTAATACAAGTACAGGCGGTT
TGCTTCTGCCTAGCGATACCAAGAGGTCTCAGATCTATGGGAGTCGTCAGATTATACTGGAGAAAGAGGAAACAGAAGAGCTAAAACGGT
TTGATGATCCAGGTTTGATGCTCATGGGTTTCAAGCCGTTGGTACTGCTGAAGAAACACCATTACCTGAGGCCCTCCCTGTTCGTGTACC
CAGAGGAGTCGCTGGTGATTGGGAGCTCAACCCTGTTCAGTGCTCTGCTCATCAAGTGTCTGGAGAAGGAGGTTGCAGCATTGTGCAGAT
ACACACCCCGCAGGAACATCCCTCCTTATTTTGTGGCTTTGGTGCCACAGGAAGAAGAGTTGGATGACCAGAAAATTCAGGTGACTCCTC
CAGGCTTCCAGCTGGTCTTTTTACCCTTTGCTGATGATAAAAGGAAGATGCCCTTTACTGAAAAAATCATGGCAACTCCAGAGCAGGTGG
GCAAGATGAAGGCTATCGTTGAGAAGCTTCGCTTCACATACAGAAGTGACAGCTTTGAGAACCCCGTGCTGCAGCAGCACTTCAGGAACC
TGGAGGCCTTGGCCTTGGATTTGATGGAGCCGGAACAAGCAGTGGACCTGACATGTTATGAGGCACAGACTTTCAACTGGGAGAACTACT
TGGAGAAGACCAAGTCGAAAGCCGCTCCATCGAGACTCTTTAACATGGATTGCCCAAACCATGGCTTCAAGGTGGGCATGAAGCTGGAGG
CCGTGGACCTGATGGAGCCCCGGCTCATCTGTGTGGCCACGGTGAAACGAGTGGTGCATCGGCTCCTCAGCATCCACTTTGACGGCTGGG
ACAGCGAGTACGACCAGTGGGTGGACTGCGAGTCCCCAGACATCTACCCCGTCGGCTGGTGTGAGCTCACCGGCTACCAGCTCCAGCCTC
CTGTGGCCGCAGAACCGGCCACACCGCTGAAGGCCAAAGAGGCCACAAAGAAGAAAAAGAAACAGTTTGGGAAGAAAAGGAAAAGAATCC
CGCCCACTAAGACGCGACCCCTCAGACAGGGGTCCAAGAAGCCCCTGCTGGAGGACGACCCTCAGGGTGCCAGGAAGATCTCGTCGGAGC
CTGTTCCTGGCGAGATCATTGCTGTGCGTGTGAAGGAAGAGCATCTAGACGTGGCCTCGCCCGACAAGGCTTCAAGTCCAGAGCTGCCTG
TCTCCGTCGAGAACATCAAGCAGGAAACAGACGACTGAGCCTTCCTGCCTCCAGCCTGGCTTCTAGCTGGAAGCCAGCCCAGCGTTTCTC
TACCACCACCACCATGCCTCCACCTGACTTTGGCTTGGAGACTGATCCTCTCTGTGTAAATTCTGCCCGGTGCTGTGAAGGCTGGACGGT
GGAGGACCTGCTGGGGTCTCCTGGGACCCGCCTGTTGCTTCTGCCCTCCCCTGTGGAAAGGTCTATATGACGGGCCGCCTGAGGCCCCAG
AACTCGTCTGTGAACCACCTTTTCCAGCCAGAGTTCCCAAAGCTGGAACGCTAGCTGCCTGCTCTTCCTTAAGATGGCCTCCCCCCGACC
CGCCACGGCCCTCAGTTGCCAGGGATGGGGCCACCACTGTCACACTGTGGAATACAAGACAGTGAACTCTGTCTGCCTGAACGAGCCATG
TAAATTAAGTTCTAGAGCAGCTCTCTGAGCAGGATAAGGTCCCCTGACAGTGAGTTGTGTGGTGGGGGCAGCCTCTGCCTCAAAAATTCA
CCAAGCAGAATGCCTCTCAGCCTCATGTGTTGGTCCTCTGCTCCTCCTAGCTCCCCAGGGATGTTGGGGACCCAGCTTGTCTCGGCAGCT
AAGAAGCAGTGACCAGGATGTGGATTTTGGCGACCTGTGTGGTGGCCTTGAGCTGCTTTCTGTGTTTGTGAGGACTGACTCCCATTTCCT
AAAGGAAATGCCCCCGGGGAGGACATTGGGAGGAAGATGGCCTGAGTGTGCACTTTGGCTCTGCTACCTGCTCCTGAAGCCCCGCTAAAA
ATAATTCATCCAAGATTCCTTTGTAGTTAAAGGGTCCAGTTCTGACTGGAGCCTCTAGAGAGCTGGGCTTGTATGTTCTTTTGGCCTTTT
GTTCCTACCTAAATGAAGAAACCATGCCTGGAGGGGCCGTGAACACAGAACCCTCAAGACAAGGATGACAGAGCTGGAGGACACATCTAG

>99781_99781_2_XRCC6-L3MBTL2_XRCC6_chr22_42054356_ENST00000360079_L3MBTL2_chr22_41622666_ENST00000216237_length(amino acids)=711AA_BP=508
MSGWESYYKTEGDEEAEEEQEENLEASGDYKYSGRDSLIFLVDASKAMFESQSEDELTPFDMSIQCIQSVYISKIISSDRDLLAVVFYGT
EKDKNSVNFKNIYVLQELDNPGAKRILELDQFKGQQGQKRFQDMMGHGSDYSLSEVLWVCANLFSDVQFKMSHKRIMLFTNEDNPHGNDS
AKASRARTKAGDLRDTGIFLDLMHLKKPGGFDISLFYRDIISIAEDEDLRVHFEESSKLEDLLRKVRAKETRKRALSRLKLKLNKDIVIS
VGIYNLVQKALKPPPIKLYRETNEPVKTKTRTFNTSTGGLLLPSDTKRSQIYGSRQIILEKEETEELKRFDDPGLMLMGFKPLVLLKKHH
YLRPSLFVYPEESLVIGSSTLFSALLIKCLEKEVAALCRYTPRRNIPPYFVALVPQEEELDDQKIQVTPPGFQLVFLPFADDKRKMPFTE
KIMATPEQVGKMKAIVEKLRFTYRSDSFENPVLQQHFRNLEALALDLMEPEQAVDLTCYEAQTFNWENYLEKTKSKAAPSRLFNMDCPNH
GFKVGMKLEAVDLMEPRLICVATVKRVVHRLLSIHFDGWDSEYDQWVDCESPDIYPVGWCELTGYQLQPPVAAEPATPLKAKEATKKKKK

--------------------------------------------------------------
>99781_99781_3_XRCC6-L3MBTL2_XRCC6_chr22_42054356_ENST00000402580_L3MBTL2_chr22_41622666_ENST00000216237_length(transcript)=3099nt_BP=1465nt
ATGCGTGGATTGTCGTCTTCTGTCCAAGTTGGTCGCTTCCCTGCGCCAAAGTGAGCAGTAGCCAACATGTCAGGGTGGGAGTCATATTAC
AAAACCGAGGGCGATGAAGAAGCAGAGGAAGAACAAGAAGAGAACCTTGAAGCAAGTGGAGACTATAAATATTCAGGAAGAGATAGTTTG
ATTTTTTTGGTTGATGCCTCCAAGGCTATGTTTGAATCTCAGAGTGAAGATGAGTTGACACCTTTTGACATGAGCATCCAGGAGCTGGAT
AATCCAGGTGCAAAACGAATTCTAGAGCTTGACCAGTTTAAGGGGCAGCAGGGACAAAAACGTTTCCAAGACATGATGGGCCACGGATCT
GACTACTCACTCAGTGAAGTGCTGTGGGTCTGTGCCAACCTCTTTAGTGATGTCCAATTCAAGATGAGTCATAAGAGGATCATGCTGTTC
ACCAATGAAGACAACCCCCATGGCAATGACAGTGCCAAAGCCAGCCGGGCCAGGACCAAAGCCGGTGATCTCCGAGATACAGGCATCTTC
CTTGACTTGATGCACCTGAAGAAACCTGGGGGCTTTGACATATCCTTGTTCTACAGAGATATCATCAGCATAGCAGAGGATGAGGACCTC
AGGGTTCACTTTGAGGAATCCAGCAAGCTAGAAGACCTGTTGCGGAAGGTTCGCGCCAAGGAGACCAGGAAGCGAGCACTCAGCAGGTTA
AAGCTGAAGCTCAACAAAGATATAGTGATCTCTGTGGGCATTTATAATCTGGTCCAGAAGGCTCTCAAGCCTCCTCCAATAAAGCTCTAT
CGGGAAACAAATGAACCAGTGAAAACCAAGACCCGGACCTTTAATACAAGTACAGGCGGTTTGCTTCTGCCTAGCGATACCAAGAGGTCT
CAGATCTATGGGAGTCGTCAGATTATACTGGAGAAAGAGGAAACAGAAGAGCTAAAACGGTTTGATGATCCAGGTTTGATGCTCATGGGT
TTCAAGCCGTTGGTACTGCTGAAGAAACACCATTACCTGAGGCCCTCCCTGTTCGTGTACCCAGAGGAGTCGCTGGTGATTGGGAGCTCA
ACCCTGTTCAGTGCTCTGCTCATCAAGTGTCTGGAGAAGGAGGTTGCAGCATTGTGCAGATACACACCCCGCAGGAACATCCCTCCTTAT
TTTGTGGCTTTGGTGCCACAGGAAGAAGAGTTGGATGACCAGAAAATTCAGGTGACTCCTCCAGGCTTCCAGCTGGTCTTTTTACCCTTT
GCTGATGATAAAAGGAAGATGCCCTTTACTGAAAAAATCATGGCAACTCCAGAGCAGGTGGGCAAGATGAAGGCTATCGTTGAGAAGCTT
CGCTTCACATACAGAAGTGACAGCTTTGAGAACCCCGTGCTGCAGCAGCACTTCAGGAACCTGGAGGCCTTGGCCTTGGATTTGATGGAG
CCGGAACAAGCAGTGGACCTGACATGTTATGAGGCACAGACTTTCAACTGGGAGAACTACTTGGAGAAGACCAAGTCGAAAGCCGCTCCA
TCGAGACTCTTTAACATGGATTGCCCAAACCATGGCTTCAAGGTGGGCATGAAGCTGGAGGCCGTGGACCTGATGGAGCCCCGGCTCATC
TGTGTGGCCACGGTGAAACGAGTGGTGCATCGGCTCCTCAGCATCCACTTTGACGGCTGGGACAGCGAGTACGACCAGTGGGTGGACTGC
GAGTCCCCAGACATCTACCCCGTCGGCTGGTGTGAGCTCACCGGCTACCAGCTCCAGCCTCCTGTGGCCGCAGAACCGGCCACACCGCTG
AAGGCCAAAGAGGCCACAAAGAAGAAAAAGAAACAGTTTGGGAAGAAAAGGAAAAGAATCCCGCCCACTAAGACGCGACCCCTCAGACAG
GGGTCCAAGAAGCCCCTGCTGGAGGACGACCCTCAGGGTGCCAGGAAGATCTCGTCGGAGCCTGTTCCTGGCGAGATCATTGCTGTGCGT
GTGAAGGAAGAGCATCTAGACGTGGCCTCGCCCGACAAGGCTTCAAGTCCAGAGCTGCCTGTCTCCGTCGAGAACATCAAGCAGGAAACA
GACGACTGAGCCTTCCTGCCTCCAGCCTGGCTTCTAGCTGGAAGCCAGCCCAGCGTTTCTCTACCACCACCACCATGCCTCCACCTGACT
TTGGCTTGGAGACTGATCCTCTCTGTGTAAATTCTGCCCGGTGCTGTGAAGGCTGGACGGTGGAGGACCTGCTGGGGTCTCCTGGGACCC
GCCTGTTGCTTCTGCCCTCCCCTGTGGAAAGGTCTATATGACGGGCCGCCTGAGGCCCCAGAACTCGTCTGTGAACCACCTTTTCCAGCC
AGAGTTCCCAAAGCTGGAACGCTAGCTGCCTGCTCTTCCTTAAGATGGCCTCCCCCCGACCCGCCACGGCCCTCAGTTGCCAGGGATGGG
GCCACCACTGTCACACTGTGGAATACAAGACAGTGAACTCTGTCTGCCTGAACGAGCCATGTAAATTAAGTTCTAGAGCAGCTCTCTGAG
CAGGATAAGGTCCCCTGACAGTGAGTTGTGTGGTGGGGGCAGCCTCTGCCTCAAAAATTCACCAAGCAGAATGCCTCTCAGCCTCATGTG
TTGGTCCTCTGCTCCTCCTAGCTCCCCAGGGATGTTGGGGACCCAGCTTGTCTCGGCAGCTAAGAAGCAGTGACCAGGATGTGGATTTTG
GCGACCTGTGTGGTGGCCTTGAGCTGCTTTCTGTGTTTGTGAGGACTGACTCCCATTTCCTAAAGGAAATGCCCCCGGGGAGGACATTGG
GAGGAAGATGGCCTGAGTGTGCACTTTGGCTCTGCTACCTGCTCCTGAAGCCCCGCTAAAAATAATTCATCCAAGATTCCTTTGTAGTTA
AAGGGTCCAGTTCTGACTGGAGCCTCTAGAGAGCTGGGCTTGTATGTTCTTTTGGCCTTTTGTTCCTACCTAAATGAAGAAACCATGCCT
GGAGGGGCCGTGAACACAGAACCCTCAAGACAAGGATGACAGAGCTGGAGGACACATCTAGCTGCCATTGCAACCTCACTGGGCTCCCCA

>99781_99781_3_XRCC6-L3MBTL2_XRCC6_chr22_42054356_ENST00000402580_L3MBTL2_chr22_41622666_ENST00000216237_length(amino acids)=670AA_BP=467
MSGWESYYKTEGDEEAEEEQEENLEASGDYKYSGRDSLIFLVDASKAMFESQSEDELTPFDMSIQELDNPGAKRILELDQFKGQQGQKRF
QDMMGHGSDYSLSEVLWVCANLFSDVQFKMSHKRIMLFTNEDNPHGNDSAKASRARTKAGDLRDTGIFLDLMHLKKPGGFDISLFYRDII
SIAEDEDLRVHFEESSKLEDLLRKVRAKETRKRALSRLKLKLNKDIVISVGIYNLVQKALKPPPIKLYRETNEPVKTKTRTFNTSTGGLL
LPSDTKRSQIYGSRQIILEKEETEELKRFDDPGLMLMGFKPLVLLKKHHYLRPSLFVYPEESLVIGSSTLFSALLIKCLEKEVAALCRYT
PRRNIPPYFVALVPQEEELDDQKIQVTPPGFQLVFLPFADDKRKMPFTEKIMATPEQVGKMKAIVEKLRFTYRSDSFENPVLQQHFRNLE
ALALDLMEPEQAVDLTCYEAQTFNWENYLEKTKSKAAPSRLFNMDCPNHGFKVGMKLEAVDLMEPRLICVATVKRVVHRLLSIHFDGWDS
EYDQWVDCESPDIYPVGWCELTGYQLQPPVAAEPATPLKAKEATKKKKKQFGKKRKRIPPTKTRPLRQGSKKPLLEDDPQGARKISSEPV

--------------------------------------------------------------
>99781_99781_4_XRCC6-L3MBTL2_XRCC6_chr22_42054356_ENST00000405506_L3MBTL2_chr22_41622666_ENST00000216237_length(transcript)=3065nt_BP=1431nt
CGCCTAGTGAGCAGTAGCCAACATGTCAGGGTGGGAGTCATATTACAAAACCGAGGGCGATGAAGAAGCAGAGGAAGAACAAGAAGAGAA
CCTTGAAGCAAGTGTGTATCCAAAGTGTGTACATCAGTAAGATCATAAGCAGTGATCGAGATCTCTTGGCTGTGGTGTTCTATGGTACCG
AGAAAGACAAAAATTCAGTGAATTTTAAAAATATTTACGTCTTACAGGAGCTGGATAATCCAGGTGCAAAACGAATTCTAGAGCTTGACC
AGTTTAAGGGGCAGCAGGGACAAAAACGTTTCCAAGACATGATGGGCCACGGATCTGACTACTCACTCAGTGAAGTGCTGTGGGTCTGTG
CCAACCTCTTTAGTGATGTCCAATTCAAGATGAGTCATAAGAGGATCATGCTGTTCACCAATGAAGACAACCCCCATGGCAATGACAGTG
CCAAAGCCAGCCGGGCCAGGACCAAAGCCGGTGATCTCCGAGATACAGGCATCTTCCTTGACTTGATGCACCTGAAGAAACCTGGGGGCT
TTGACATATCCTTGTTCTACAGAGATATCATCAGCATAGCAGAGGATGAGGACCTCAGGGTTCACTTTGAGGAATCCAGCAAGCTAGAAG
ACCTGTTGCGGAAGGTTCGCGCCAAGGAGACCAGGAAGCGAGCACTCAGCAGGTTAAAGCTGAAGCTCAACAAAGATATAGTGATCTCTG
TGGGCATTTATAATCTGGTCCAGAAGGCTCTCAAGCCTCCTCCAATAAAGCTCTATCGGGAAACAAATGAACCAGTGAAAACCAAGACCC
GGACCTTTAATACAAGTACAGGCGGTTTGCTTCTGCCTAGCGATACCAAGAGGTCTCAGATCTATGGGAGTCGTCAGATTATACTGGAGA
AAGAGGAAACAGAAGAGCTAAAACGGTTTGATGATCCAGGTTTGATGCTCATGGGTTTCAAGCCGTTGGTACTGCTGAAGAAACACCATT
ACCTGAGGCCCTCCCTGTTCGTGTACCCAGAGGAGTCGCTGGTGATTGGGAGCTCAACCCTGTTCAGTGCTCTGCTCATCAAGTGTCTGG
AGAAGGAGGTTGCAGCATTGTGCAGATACACACCCCGCAGGAACATCCCTCCTTATTTTGTGGCTTTGGTGCCACAGGAAGAAGAGTTGG
ATGACCAGAAAATTCAGGTGACTCCTCCAGGCTTCCAGCTGGTCTTTTTACCCTTTGCTGATGATAAAAGGAAGATGCCCTTTACTGAAA
AAATCATGGCAACTCCAGAGCAGGTGGGCAAGATGAAGGCTATCGTTGAGAAGCTTCGCTTCACATACAGAAGTGACAGCTTTGAGAACC
CCGTGCTGCAGCAGCACTTCAGGAACCTGGAGGCCTTGGCCTTGGATTTGATGGAGCCGGAACAAGCAGTGGACCTGACATGTTATGAGG
CACAGACTTTCAACTGGGAGAACTACTTGGAGAAGACCAAGTCGAAAGCCGCTCCATCGAGACTCTTTAACATGGATTGCCCAAACCATG
GCTTCAAGGTGGGCATGAAGCTGGAGGCCGTGGACCTGATGGAGCCCCGGCTCATCTGTGTGGCCACGGTGAAACGAGTGGTGCATCGGC
TCCTCAGCATCCACTTTGACGGCTGGGACAGCGAGTACGACCAGTGGGTGGACTGCGAGTCCCCAGACATCTACCCCGTCGGCTGGTGTG
AGCTCACCGGCTACCAGCTCCAGCCTCCTGTGGCCGCAGAACCGGCCACACCGCTGAAGGCCAAAGAGGCCACAAAGAAGAAAAAGAAAC
AGTTTGGGAAGAAAAGGAAAAGAATCCCGCCCACTAAGACGCGACCCCTCAGACAGGGGTCCAAGAAGCCCCTGCTGGAGGACGACCCTC
AGGGTGCCAGGAAGATCTCGTCGGAGCCTGTTCCTGGCGAGATCATTGCTGTGCGTGTGAAGGAAGAGCATCTAGACGTGGCCTCGCCCG
ACAAGGCTTCAAGTCCAGAGCTGCCTGTCTCCGTCGAGAACATCAAGCAGGAAACAGACGACTGAGCCTTCCTGCCTCCAGCCTGGCTTC
TAGCTGGAAGCCAGCCCAGCGTTTCTCTACCACCACCACCATGCCTCCACCTGACTTTGGCTTGGAGACTGATCCTCTCTGTGTAAATTC
TGCCCGGTGCTGTGAAGGCTGGACGGTGGAGGACCTGCTGGGGTCTCCTGGGACCCGCCTGTTGCTTCTGCCCTCCCCTGTGGAAAGGTC
TATATGACGGGCCGCCTGAGGCCCCAGAACTCGTCTGTGAACCACCTTTTCCAGCCAGAGTTCCCAAAGCTGGAACGCTAGCTGCCTGCT
CTTCCTTAAGATGGCCTCCCCCCGACCCGCCACGGCCCTCAGTTGCCAGGGATGGGGCCACCACTGTCACACTGTGGAATACAAGACAGT
GAACTCTGTCTGCCTGAACGAGCCATGTAAATTAAGTTCTAGAGCAGCTCTCTGAGCAGGATAAGGTCCCCTGACAGTGAGTTGTGTGGT
GGGGGCAGCCTCTGCCTCAAAAATTCACCAAGCAGAATGCCTCTCAGCCTCATGTGTTGGTCCTCTGCTCCTCCTAGCTCCCCAGGGATG
TTGGGGACCCAGCTTGTCTCGGCAGCTAAGAAGCAGTGACCAGGATGTGGATTTTGGCGACCTGTGTGGTGGCCTTGAGCTGCTTTCTGT
GTTTGTGAGGACTGACTCCCATTTCCTAAAGGAAATGCCCCCGGGGAGGACATTGGGAGGAAGATGGCCTGAGTGTGCACTTTGGCTCTG
CTACCTGCTCCTGAAGCCCCGCTAAAAATAATTCATCCAAGATTCCTTTGTAGTTAAAGGGTCCAGTTCTGACTGGAGCCTCTAGAGAGC
TGGGCTTGTATGTTCTTTTGGCCTTTTGTTCCTACCTAAATGAAGAAACCATGCCTGGAGGGGCCGTGAACACAGAACCCTCAAGACAAG
GATGACAGAGCTGGAGGACACATCTAGCTGCCATTGCAACCTCACTGGGCTCCCCAGACTCTGTGTGTGAGAAATTAAACCCCCTGCTTG

>99781_99781_4_XRCC6-L3MBTL2_XRCC6_chr22_42054356_ENST00000405506_L3MBTL2_chr22_41622666_ENST00000216237_length(amino acids)=661AA_BP=458
MKKQRKNKKRTLKQVCIQSVYISKIISSDRDLLAVVFYGTEKDKNSVNFKNIYVLQELDNPGAKRILELDQFKGQQGQKRFQDMMGHGSD
YSLSEVLWVCANLFSDVQFKMSHKRIMLFTNEDNPHGNDSAKASRARTKAGDLRDTGIFLDLMHLKKPGGFDISLFYRDIISIAEDEDLR
VHFEESSKLEDLLRKVRAKETRKRALSRLKLKLNKDIVISVGIYNLVQKALKPPPIKLYRETNEPVKTKTRTFNTSTGGLLLPSDTKRSQ
IYGSRQIILEKEETEELKRFDDPGLMLMGFKPLVLLKKHHYLRPSLFVYPEESLVIGSSTLFSALLIKCLEKEVAALCRYTPRRNIPPYF
VALVPQEEELDDQKIQVTPPGFQLVFLPFADDKRKMPFTEKIMATPEQVGKMKAIVEKLRFTYRSDSFENPVLQQHFRNLEALALDLMEP
EQAVDLTCYEAQTFNWENYLEKTKSKAAPSRLFNMDCPNHGFKVGMKLEAVDLMEPRLICVATVKRVVHRLLSIHFDGWDSEYDQWVDCE
SPDIYPVGWCELTGYQLQPPVAAEPATPLKAKEATKKKKKQFGKKRKRIPPTKTRPLRQGSKKPLLEDDPQGARKISSEPVPGEIIAVRV

--------------------------------------------------------------
>99781_99781_5_XRCC6-L3MBTL2_XRCC6_chr22_42054356_ENST00000405878_L3MBTL2_chr22_41622666_ENST00000216237_length(transcript)=3302nt_BP=1668nt
AAGTGTGCGAATCCGAGGAGCAGCGACAGACTCGAGACCACGCTCCTTCCTCGGGAAGGAGGCGGCACCTCGCGTTTGAGGCCCGCCTGC
GTTTGAGGCCCGCCTGCGCTTGCGGCCCGCCTGCGCTTGAGTGAGCAGTAGCCAACATGTCAGGGTGGGAGTCATATTACAAAACCGAGG
GCGATGAAGAAGCAGAGGAAGAACAAGAAGAGAACCTTGAAGCAAGTGGAGACTATAAATATTCAGGAAGAGATAGTTTGATTTTTTTGG
TTGATGCCTCCAAGGCTATGTTTGAATCTCAGAGTGAAGATGAGTTGACACCTTTTGACATGAGCATCCAGTGTATCCAAAGTGTGTACA
TCAGTAAGATCATAAGCAGTGATCGAGATCTCTTGGCTGTGGTGTTCTATGGTACCGAGAAAGACAAAAATTCAGTGAATTTTAAAAATA
TTTACGTCTTACAGGAGCTGGATAATCCAGGTGCAAAACGAATTCTAGAGCTTGACCAGTTTAAGGGGCAGCAGGGACAAAAACGTTTCC
AAGACATGATGGGCCACGGATCTGACTACTCACTCAGTGAAGTGCTGTGGGTCTGTGCCAACCTCTTTAGTGATGTCCAATTCAAGATGA
GTCATAAGAGGATCATGCTGTTCACCAATGAAGACAACCCCCATGGCAATGACAGTGCCAAAGCCAGCCGGGCCAGGACCAAAGCCGGTG
ATCTCCGAGATACAGGCATCTTCCTTGACTTGATGCACCTGAAGAAACCTGGGGGCTTTGACATATCCTTGTTCTACAGAGATATCATCA
GCATAGCAGAGGATGAGGACCTCAGGGTTCACTTTGAGGAATCCAGCAAGCTAGAAGACCTGTTGCGGAAGGTTCGCGCCAAGGAGACCA
GGAAGCGAGCACTCAGCAGGTTAAAGCTGAAGCTCAACAAAGATATAGTGATCTCTGTGGGCATTTATAATCTGGTCCAGAAGGCTCTCA
AGCCTCCTCCAATAAAGCTCTATCGGGAAACAAATGAACCAGTGAAAACCAAGACCCGGACCTTTAATACAAGTACAGGCGGTTTGCTTC
TGCCTAGCGATACCAAGAGGTCTCAGATCTATGGGAGTCGTCAGATTATACTGGAGAAAGAGGAAACAGAAGAGCTAAAACGGTTTGATG
ATCCAGGTTTGATGCTCATGGGTTTCAAGCCGTTGGTACTGCTGAAGAAACACCATTACCTGAGGCCCTCCCTGTTCGTGTACCCAGAGG
AGTCGCTGGTGATTGGGAGCTCAACCCTGTTCAGTGCTCTGCTCATCAAGTGTCTGGAGAAGGAGGTTGCAGCATTGTGCAGATACACAC
CCCGCAGGAACATCCCTCCTTATTTTGTGGCTTTGGTGCCACAGGAAGAAGAGTTGGATGACCAGAAAATTCAGGTGACTCCTCCAGGCT
TCCAGCTGGTCTTTTTACCCTTTGCTGATGATAAAAGGAAGATGCCCTTTACTGAAAAAATCATGGCAACTCCAGAGCAGGTGGGCAAGA
TGAAGGCTATCGTTGAGAAGCTTCGCTTCACATACAGAAGTGACAGCTTTGAGAACCCCGTGCTGCAGCAGCACTTCAGGAACCTGGAGG
CCTTGGCCTTGGATTTGATGGAGCCGGAACAAGCAGTGGACCTGACATGTTATGAGGCACAGACTTTCAACTGGGAGAACTACTTGGAGA
AGACCAAGTCGAAAGCCGCTCCATCGAGACTCTTTAACATGGATTGCCCAAACCATGGCTTCAAGGTGGGCATGAAGCTGGAGGCCGTGG
ACCTGATGGAGCCCCGGCTCATCTGTGTGGCCACGGTGAAACGAGTGGTGCATCGGCTCCTCAGCATCCACTTTGACGGCTGGGACAGCG
AGTACGACCAGTGGGTGGACTGCGAGTCCCCAGACATCTACCCCGTCGGCTGGTGTGAGCTCACCGGCTACCAGCTCCAGCCTCCTGTGG
CCGCAGAACCGGCCACACCGCTGAAGGCCAAAGAGGCCACAAAGAAGAAAAAGAAACAGTTTGGGAAGAAAAGGAAAAGAATCCCGCCCA
CTAAGACGCGACCCCTCAGACAGGGGTCCAAGAAGCCCCTGCTGGAGGACGACCCTCAGGGTGCCAGGAAGATCTCGTCGGAGCCTGTTC
CTGGCGAGATCATTGCTGTGCGTGTGAAGGAAGAGCATCTAGACGTGGCCTCGCCCGACAAGGCTTCAAGTCCAGAGCTGCCTGTCTCCG
TCGAGAACATCAAGCAGGAAACAGACGACTGAGCCTTCCTGCCTCCAGCCTGGCTTCTAGCTGGAAGCCAGCCCAGCGTTTCTCTACCAC
CACCACCATGCCTCCACCTGACTTTGGCTTGGAGACTGATCCTCTCTGTGTAAATTCTGCCCGGTGCTGTGAAGGCTGGACGGTGGAGGA
CCTGCTGGGGTCTCCTGGGACCCGCCTGTTGCTTCTGCCCTCCCCTGTGGAAAGGTCTATATGACGGGCCGCCTGAGGCCCCAGAACTCG
TCTGTGAACCACCTTTTCCAGCCAGAGTTCCCAAAGCTGGAACGCTAGCTGCCTGCTCTTCCTTAAGATGGCCTCCCCCCGACCCGCCAC
GGCCCTCAGTTGCCAGGGATGGGGCCACCACTGTCACACTGTGGAATACAAGACAGTGAACTCTGTCTGCCTGAACGAGCCATGTAAATT
AAGTTCTAGAGCAGCTCTCTGAGCAGGATAAGGTCCCCTGACAGTGAGTTGTGTGGTGGGGGCAGCCTCTGCCTCAAAAATTCACCAAGC
AGAATGCCTCTCAGCCTCATGTGTTGGTCCTCTGCTCCTCCTAGCTCCCCAGGGATGTTGGGGACCCAGCTTGTCTCGGCAGCTAAGAAG
CAGTGACCAGGATGTGGATTTTGGCGACCTGTGTGGTGGCCTTGAGCTGCTTTCTGTGTTTGTGAGGACTGACTCCCATTTCCTAAAGGA
AATGCCCCCGGGGAGGACATTGGGAGGAAGATGGCCTGAGTGTGCACTTTGGCTCTGCTACCTGCTCCTGAAGCCCCGCTAAAAATAATT
CATCCAAGATTCCTTTGTAGTTAAAGGGTCCAGTTCTGACTGGAGCCTCTAGAGAGCTGGGCTTGTATGTTCTTTTGGCCTTTTGTTCCT
ACCTAAATGAAGAAACCATGCCTGGAGGGGCCGTGAACACAGAACCCTCAAGACAAGGATGACAGAGCTGGAGGACACATCTAGCTGCCA

>99781_99781_5_XRCC6-L3MBTL2_XRCC6_chr22_42054356_ENST00000405878_L3MBTL2_chr22_41622666_ENST00000216237_length(amino acids)=711AA_BP=508
MSGWESYYKTEGDEEAEEEQEENLEASGDYKYSGRDSLIFLVDASKAMFESQSEDELTPFDMSIQCIQSVYISKIISSDRDLLAVVFYGT
EKDKNSVNFKNIYVLQELDNPGAKRILELDQFKGQQGQKRFQDMMGHGSDYSLSEVLWVCANLFSDVQFKMSHKRIMLFTNEDNPHGNDS
AKASRARTKAGDLRDTGIFLDLMHLKKPGGFDISLFYRDIISIAEDEDLRVHFEESSKLEDLLRKVRAKETRKRALSRLKLKLNKDIVIS
VGIYNLVQKALKPPPIKLYRETNEPVKTKTRTFNTSTGGLLLPSDTKRSQIYGSRQIILEKEETEELKRFDDPGLMLMGFKPLVLLKKHH
YLRPSLFVYPEESLVIGSSTLFSALLIKCLEKEVAALCRYTPRRNIPPYFVALVPQEEELDDQKIQVTPPGFQLVFLPFADDKRKMPFTE
KIMATPEQVGKMKAIVEKLRFTYRSDSFENPVLQQHFRNLEALALDLMEPEQAVDLTCYEAQTFNWENYLEKTKSKAAPSRLFNMDCPNH
GFKVGMKLEAVDLMEPRLICVATVKRVVHRLLSIHFDGWDSEYDQWVDCESPDIYPVGWCELTGYQLQPPVAAEPATPLKAKEATKKKKK

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>99781_99781_6_XRCC6-L3MBTL2_XRCC6_chr22_42054356_ENST00000428575_L3MBTL2_chr22_41622666_ENST00000216237_length(transcript)=3098nt_BP=1464nt
GTCGTCTTCTGTCCAAGTTGGTCGCTTCCCTGCGCCAAAGTGAGCAGTAGCCAACATGTCAGGGTGGGAGTCATATTACAAAACCGAGGG
CGATGAAGAAGCAGAGGAAGAACAAGAAGAGAACCTTGAAGCAAGTGTGTATCCAAAGTGTGTACATCAGTAAGATCATAAGCAGTGATC
GAGATCTCTTGGCTGTGGTGTTCTATGGTACCGAGAAAGACAAAAATTCAGTGAATTTTAAAAATATTTACGTCTTACAGGAGCTGGATA
ATCCAGGTGCAAAACGAATTCTAGAGCTTGACCAGTTTAAGGGGCAGCAGGGACAAAAACGTTTCCAAGACATGATGGGCCACGGATCTG
ACTACTCACTCAGTGAAGTGCTGTGGGTCTGTGCCAACCTCTTTAGTGATGTCCAATTCAAGATGAGTCATAAGAGGATCATGCTGTTCA
CCAATGAAGACAACCCCCATGGCAATGACAGTGCCAAAGCCAGCCGGGCCAGGACCAAAGCCGGTGATCTCCGAGATACAGGCATCTTCC
TTGACTTGATGCACCTGAAGAAACCTGGGGGCTTTGACATATCCTTGTTCTACAGAGATATCATCAGCATAGCAGAGGATGAGGACCTCA
GGGTTCACTTTGAGGAATCCAGCAAGCTAGAAGACCTGTTGCGGAAGGTTCGCGCCAAGGAGACCAGGAAGCGAGCACTCAGCAGGTTAA
AGCTGAAGCTCAACAAAGATATAGTGATCTCTGTGGGCATTTATAATCTGGTCCAGAAGGCTCTCAAGCCTCCTCCAATAAAGCTCTATC
GGGAAACAAATGAACCAGTGAAAACCAAGACCCGGACCTTTAATACAAGTACAGGCGGTTTGCTTCTGCCTAGCGATACCAAGAGGTCTC
AGATCTATGGGAGTCGTCAGATTATACTGGAGAAAGAGGAAACAGAAGAGCTAAAACGGTTTGATGATCCAGGTTTGATGCTCATGGGTT
TCAAGCCGTTGGTACTGCTGAAGAAACACCATTACCTGAGGCCCTCCCTGTTCGTGTACCCAGAGGAGTCGCTGGTGATTGGGAGCTCAA
CCCTGTTCAGTGCTCTGCTCATCAAGTGTCTGGAGAAGGAGGTTGCAGCATTGTGCAGATACACACCCCGCAGGAACATCCCTCCTTATT
TTGTGGCTTTGGTGCCACAGGAAGAAGAGTTGGATGACCAGAAAATTCAGGTGACTCCTCCAGGCTTCCAGCTGGTCTTTTTACCCTTTG
CTGATGATAAAAGGAAGATGCCCTTTACTGAAAAAATCATGGCAACTCCAGAGCAGGTGGGCAAGATGAAGGCTATCGTTGAGAAGCTTC
GCTTCACATACAGAAGTGACAGCTTTGAGAACCCCGTGCTGCAGCAGCACTTCAGGAACCTGGAGGCCTTGGCCTTGGATTTGATGGAGC
CGGAACAAGCAGTGGACCTGACATGTTATGAGGCACAGACTTTCAACTGGGAGAACTACTTGGAGAAGACCAAGTCGAAAGCCGCTCCAT
CGAGACTCTTTAACATGGATTGCCCAAACCATGGCTTCAAGGTGGGCATGAAGCTGGAGGCCGTGGACCTGATGGAGCCCCGGCTCATCT
GTGTGGCCACGGTGAAACGAGTGGTGCATCGGCTCCTCAGCATCCACTTTGACGGCTGGGACAGCGAGTACGACCAGTGGGTGGACTGCG
AGTCCCCAGACATCTACCCCGTCGGCTGGTGTGAGCTCACCGGCTACCAGCTCCAGCCTCCTGTGGCCGCAGAACCGGCCACACCGCTGA
AGGCCAAAGAGGCCACAAAGAAGAAAAAGAAACAGTTTGGGAAGAAAAGGAAAAGAATCCCGCCCACTAAGACGCGACCCCTCAGACAGG
GGTCCAAGAAGCCCCTGCTGGAGGACGACCCTCAGGGTGCCAGGAAGATCTCGTCGGAGCCTGTTCCTGGCGAGATCATTGCTGTGCGTG
TGAAGGAAGAGCATCTAGACGTGGCCTCGCCCGACAAGGCTTCAAGTCCAGAGCTGCCTGTCTCCGTCGAGAACATCAAGCAGGAAACAG
ACGACTGAGCCTTCCTGCCTCCAGCCTGGCTTCTAGCTGGAAGCCAGCCCAGCGTTTCTCTACCACCACCACCATGCCTCCACCTGACTT
TGGCTTGGAGACTGATCCTCTCTGTGTAAATTCTGCCCGGTGCTGTGAAGGCTGGACGGTGGAGGACCTGCTGGGGTCTCCTGGGACCCG
CCTGTTGCTTCTGCCCTCCCCTGTGGAAAGGTCTATATGACGGGCCGCCTGAGGCCCCAGAACTCGTCTGTGAACCACCTTTTCCAGCCA
GAGTTCCCAAAGCTGGAACGCTAGCTGCCTGCTCTTCCTTAAGATGGCCTCCCCCCGACCCGCCACGGCCCTCAGTTGCCAGGGATGGGG
CCACCACTGTCACACTGTGGAATACAAGACAGTGAACTCTGTCTGCCTGAACGAGCCATGTAAATTAAGTTCTAGAGCAGCTCTCTGAGC
AGGATAAGGTCCCCTGACAGTGAGTTGTGTGGTGGGGGCAGCCTCTGCCTCAAAAATTCACCAAGCAGAATGCCTCTCAGCCTCATGTGT
TGGTCCTCTGCTCCTCCTAGCTCCCCAGGGATGTTGGGGACCCAGCTTGTCTCGGCAGCTAAGAAGCAGTGACCAGGATGTGGATTTTGG
CGACCTGTGTGGTGGCCTTGAGCTGCTTTCTGTGTTTGTGAGGACTGACTCCCATTTCCTAAAGGAAATGCCCCCGGGGAGGACATTGGG
AGGAAGATGGCCTGAGTGTGCACTTTGGCTCTGCTACCTGCTCCTGAAGCCCCGCTAAAAATAATTCATCCAAGATTCCTTTGTAGTTAA
AGGGTCCAGTTCTGACTGGAGCCTCTAGAGAGCTGGGCTTGTATGTTCTTTTGGCCTTTTGTTCCTACCTAAATGAAGAAACCATGCCTG
GAGGGGCCGTGAACACAGAACCCTCAAGACAAGGATGACAGAGCTGGAGGACACATCTAGCTGCCATTGCAACCTCACTGGGCTCCCCAG

>99781_99781_6_XRCC6-L3MBTL2_XRCC6_chr22_42054356_ENST00000428575_L3MBTL2_chr22_41622666_ENST00000216237_length(amino acids)=661AA_BP=458
MKKQRKNKKRTLKQVCIQSVYISKIISSDRDLLAVVFYGTEKDKNSVNFKNIYVLQELDNPGAKRILELDQFKGQQGQKRFQDMMGHGSD
YSLSEVLWVCANLFSDVQFKMSHKRIMLFTNEDNPHGNDSAKASRARTKAGDLRDTGIFLDLMHLKKPGGFDISLFYRDIISIAEDEDLR
VHFEESSKLEDLLRKVRAKETRKRALSRLKLKLNKDIVISVGIYNLVQKALKPPPIKLYRETNEPVKTKTRTFNTSTGGLLLPSDTKRSQ
IYGSRQIILEKEETEELKRFDDPGLMLMGFKPLVLLKKHHYLRPSLFVYPEESLVIGSSTLFSALLIKCLEKEVAALCRYTPRRNIPPYF
VALVPQEEELDDQKIQVTPPGFQLVFLPFADDKRKMPFTEKIMATPEQVGKMKAIVEKLRFTYRSDSFENPVLQQHFRNLEALALDLMEP
EQAVDLTCYEAQTFNWENYLEKTKSKAAPSRLFNMDCPNHGFKVGMKLEAVDLMEPRLICVATVKRVVHRLLSIHFDGWDSEYDQWVDCE
SPDIYPVGWCELTGYQLQPPVAAEPATPLKAKEATKKKKKQFGKKRKRIPPTKTRPLRQGSKKPLLEDDPQGARKISSEPVPGEIIAVRV

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Fusion Gene PPI Analysis for XRCC6-L3MBTL2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneXRCC6chr22:42054356chr22:41622666ENST00000359308+1012550_609507.3333333333333610.0DEAF1
HgeneXRCC6chr22:42054356chr22:41622666ENST00000360079+1113550_609507.3333333333333610.0DEAF1
HgeneXRCC6chr22:42054356chr22:41622666ENST00000405878+1113550_609507.3333333333333610.0DEAF1


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for XRCC6-L3MBTL2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for XRCC6-L3MBTL2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource