FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:XXYLT1-TPRG1 (FusionGDB2 ID:99842)

Fusion Gene Summary for XXYLT1-TPRG1

check button Fusion gene summary
Fusion gene informationFusion gene name: XXYLT1-TPRG1
Fusion gene ID: 99842
HgeneTgene
Gene symbol

XXYLT1

TPRG1

Gene ID

152002

285386

Gene namexyloside xylosyltransferase 1tumor protein p63 regulated 1
SynonymsC3orf21FAM79B
Cytomap

3q29

3q28

Type of geneprotein-codingprotein-coding
Descriptionxyloside xylosyltransferase 1UDP-xylose:alpha-xyloside alpha-1,3-xylosyltransferasetumor protein p63-regulated gene 1 proteinfamily with sequence similarity 79, member B
Modification date2020031320200313
UniProtAcc

Q8NBI6

.
Ensembl transtripts involved in fusion geneENST00000310380, ENST00000355729, 
ENST00000429994, ENST00000437101, 
ENST00000356740, ENST00000460582, 
ENST00000488841, ENST00000345063, 
ENST00000433971, 
Fusion gene scores* DoF score10 X 6 X 7=42012 X 7 X 6=504
# samples 1116
** MAII scorelog2(11/420*10)=-1.93288580414146
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(16/504*10)=-1.65535182861255
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: XXYLT1 [Title/Abstract] AND TPRG1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointXXYLT1(194877178)-TPRG1(189028175), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneXXYLT1

GO:0016266

O-glycan processing

8982869|22117070


check buttonFusion gene breakpoints across XXYLT1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across TPRG1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUSCTCGA-22-4591-01AXXYLT1chr3

194877178

-TPRG1chr3

189028175

+


Top

Fusion Gene ORF analysis for XXYLT1-TPRG1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000310380ENST00000488841XXYLT1chr3

194877178

-TPRG1chr3

189028175

+
5CDS-intronENST00000355729ENST00000488841XXYLT1chr3

194877178

-TPRG1chr3

189028175

+
5CDS-intronENST00000429994ENST00000488841XXYLT1chr3

194877178

-TPRG1chr3

189028175

+
5CDS-intronENST00000437101ENST00000488841XXYLT1chr3

194877178

-TPRG1chr3

189028175

+
Frame-shiftENST00000437101ENST00000345063XXYLT1chr3

194877178

-TPRG1chr3

189028175

+
Frame-shiftENST00000437101ENST00000433971XXYLT1chr3

194877178

-TPRG1chr3

189028175

+
In-frameENST00000310380ENST00000345063XXYLT1chr3

194877178

-TPRG1chr3

189028175

+
In-frameENST00000310380ENST00000433971XXYLT1chr3

194877178

-TPRG1chr3

189028175

+
In-frameENST00000355729ENST00000345063XXYLT1chr3

194877178

-TPRG1chr3

189028175

+
In-frameENST00000355729ENST00000433971XXYLT1chr3

194877178

-TPRG1chr3

189028175

+
In-frameENST00000429994ENST00000345063XXYLT1chr3

194877178

-TPRG1chr3

189028175

+
In-frameENST00000429994ENST00000433971XXYLT1chr3

194877178

-TPRG1chr3

189028175

+
intron-3CDSENST00000356740ENST00000345063XXYLT1chr3

194877178

-TPRG1chr3

189028175

+
intron-3CDSENST00000356740ENST00000433971XXYLT1chr3

194877178

-TPRG1chr3

189028175

+
intron-3CDSENST00000460582ENST00000345063XXYLT1chr3

194877178

-TPRG1chr3

189028175

+
intron-3CDSENST00000460582ENST00000433971XXYLT1chr3

194877178

-TPRG1chr3

189028175

+
intron-intronENST00000356740ENST00000488841XXYLT1chr3

194877178

-TPRG1chr3

189028175

+
intron-intronENST00000460582ENST00000488841XXYLT1chr3

194877178

-TPRG1chr3

189028175

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000310380XXYLT1chr3194877178-ENST00000433971TPRG1chr3189028175+14848941091242377
ENST00000310380XXYLT1chr3194877178-ENST00000345063TPRG1chr3189028175+57278941091242377
ENST00000429994XXYLT1chr3194877178-ENST00000433971TPRG1chr3189028175+102043068778236
ENST00000429994XXYLT1chr3194877178-ENST00000345063TPRG1chr3189028175+526343068778236
ENST00000355729XXYLT1chr3194877178-ENST00000433971TPRG1chr3189028175+7661760524174
ENST00000355729XXYLT1chr3194877178-ENST00000345063TPRG1chr3189028175+50091760524174

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000310380ENST00000433971XXYLT1chr3194877178-TPRG1chr3189028175+0.0047830540.99521697
ENST00000310380ENST00000345063XXYLT1chr3194877178-TPRG1chr3189028175+0.0005630950.9994369
ENST00000429994ENST00000433971XXYLT1chr3194877178-TPRG1chr3189028175+0.0022017160.9977983
ENST00000429994ENST00000345063XXYLT1chr3194877178-TPRG1chr3189028175+0.0013130440.99868697
ENST00000355729ENST00000433971XXYLT1chr3194877178-TPRG1chr3189028175+0.0123179760.98768204
ENST00000355729ENST00000345063XXYLT1chr3194877178-TPRG1chr3189028175+0.0108275920.98917234

Top

Fusion Genomic Features for XXYLT1-TPRG1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
XXYLT1chr3194877177-TPRG1chr3189028174+2.77E-050.99997234
XXYLT1chr3194877177-TPRG1chr3189028174+2.77E-050.99997234

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for XXYLT1-TPRG1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr3:194877178/chr3:189028175)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
XXYLT1

Q8NBI6

.
FUNCTION: Alpha-1,3-xylosyltransferase, which elongates the O-linked xylose-glucose disaccharide attached to EGF-like repeats in the extracellular domain of target proteins by catalyzing the addition of the second xylose (PubMed:22117070, PubMed:8982869). Known targets include Notch proteins and coagulation factors, such as F9 (PubMed:22117070, PubMed:8982869). {ECO:0000269|PubMed:22117070, ECO:0000269|PubMed:8982869}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneXXYLT1chr3:194877178chr3:189028175ENST00000310380-34104_106261394.0RegionUDP-alpha-D-xylose binding
HgeneXXYLT1chr3:194877178chr3:189028175ENST00000310380-341_23261394.0Topological domainCytoplasmic
HgeneXXYLT1chr3:194877178chr3:189028175ENST00000355729-231_2358191.0Topological domainCytoplasmic
HgeneXXYLT1chr3:194877178chr3:189028175ENST00000437101-451_2358191.0Topological domainCytoplasmic
HgeneXXYLT1chr3:194877178chr3:189028175ENST00000310380-3424_44261394.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
HgeneXXYLT1chr3:194877178chr3:189028175ENST00000355729-2324_4458191.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
HgeneXXYLT1chr3:194877178chr3:189028175ENST00000437101-4524_4458191.0TransmembraneHelical%3B Signal-anchor for type II membrane protein

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneXXYLT1chr3:194877178chr3:189028175ENST00000355729-23104_10658191.0RegionUDP-alpha-D-xylose binding
HgeneXXYLT1chr3:194877178chr3:189028175ENST00000356740-12104_1060188.0RegionUDP-alpha-D-xylose binding
HgeneXXYLT1chr3:194877178chr3:189028175ENST00000437101-45104_10658191.0RegionUDP-alpha-D-xylose binding
HgeneXXYLT1chr3:194877178chr3:189028175ENST00000310380-3445_393261394.0Topological domainLumenal
HgeneXXYLT1chr3:194877178chr3:189028175ENST00000355729-2345_39358191.0Topological domainLumenal
HgeneXXYLT1chr3:194877178chr3:189028175ENST00000356740-121_230188.0Topological domainCytoplasmic
HgeneXXYLT1chr3:194877178chr3:189028175ENST00000356740-1245_3930188.0Topological domainLumenal
HgeneXXYLT1chr3:194877178chr3:189028175ENST00000437101-4545_39358191.0Topological domainLumenal
HgeneXXYLT1chr3:194877178chr3:189028175ENST00000356740-1224_440188.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneTPRG1chr3:194877178chr3:189028175ENST000003450633668_240159276.0DomainhSac2
TgeneTPRG1chr3:194877178chr3:189028175ENST0000043397181168_240159276.0DomainhSac2


Top

Fusion Gene Sequence for XXYLT1-TPRG1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>99842_99842_1_XXYLT1-TPRG1_XXYLT1_chr3_194877178_ENST00000310380_TPRG1_chr3_189028175_ENST00000345063_length(transcript)=5727nt_BP=894nt
CCCCTTTCATGGCCGCCGCCTGGCGCCGGGGCTAAGTGGCCGCCGGCGTCCGGGTACCCGAGGGCTCTCCCGCGTTGCTGGCACCGCTGG
CGCCGCGGTCTCGTAGCGCATGGGCCTCCTCCGAGGCGGGCTCCCATGCGCTCGGGCCATGGCGCGCCTGGGCGCTGTGCGCTCCCACTA
CTGCGCCCTGCTGCTGGCCGCGGCGCTGGCCGTCTGCGCCTTCTACTACCTCGGCTCAGGCCGGGAGACCTTCTCCAGCGCCACCAAGAG
GCTGAAGGAGGCCCGCGCCGGGGCTCCCGCCGCGCCCTCGCCGCCCGCGCTGGAGCTAGCGCGGGGCTCCGTGGCGCCAGCCCCCGGCGC
GAAGGCCAAGAGCTTGGAGGGCGGCGGTGCCGGGCCGGTGGACTACCACCTGCTGATGATGTTCACCAAGGCGGAGCACAATGCCGCGCT
GCAGGCCAAGGCCCGCGTCGCGCTGCGCTCACTGCTGCGCCTCGCCAAGTTCGAGGCGCACGAGGTGCTTAACCTTCACTTCGTGAGCGA
GGAGGCCAGCCGCGAGGTGGCCAAGGGCCTGCTGCGGGAGCTCCTGCCGCCCGCCGCTGGCTTCAAGTGCAAGGTCATCTTCCACGATGT
TGCTGTGCTGACGGATAAGCTCTTCCCCATCGTGGAGGCCATGCAGAAGCACTTCAGTGCTGGCTTGGGAACCTACTACAGTGACTCCAT
CTTCTTCCTCTCGGTCGCCATGCATCAGATCATGCCCAAAGAGATCCTGCAGATCATTCAGCTGGACCTAGACCTGAAGTTTAAGACCAA
CATCCGGGAGTTGTTTGAGGAATTTGACAGTTTCCTGCCAGGCGCCATCATCGGCATAGCCCGGGAGATGCAGCCAGTTTACAGGAGACA
AGGAGAAGGCCTTAGGATCTACTGGGGGAGTCCGGAGGAGCAGTCTCTTCTGTCCCGCTGGAACCCATGGTCCACTGAAGTTCCTTATGC
TACTTTCACTGAGCATCCTATGAAATACACCAGTGAGAAATTCCTTGAAATTTGCAAGTTGTCTGGGTTCATGTCTAAGCTTGTTCCAGC
TATCCAGAATGCCCACAAGAATTCAACTGGATCTGGAAGAGGAAAGAAACTGATGGTGTTAACTGAACCCATTTTGATTGAGACCTACAC
AGGGCTGATGTCATTCATTGGAAACCGCAACAAACTTGGCTATTCCCTTGCCCGTGGGAGTATTGGTTTTTGAGAGTCTTTTTGGTACCA
TAAGCATATCATCCACAGATATGTCACTTTGAAAATTCCAGTTTGACCCACGCTATTTTTGGACTGAAACAATTAATTATTTTTAAATGA
CGCTTTATGATTTAGAAATTTAGTATTTCCGAAAATTTAAAAGCTTGATTGGACTGATAGATACACACTTTAGACCTCATACAAGAATAA
TCAAATTTTCTTAAAACTAGAAAATAAATGCTGCTGAGCCTATCAAATACTGTTATCAAATGAGTGCCTGATCATCAACTCAGGAAAGAA
GACTCTAAGTCCTGTTGCTTCAGCTCTCTAAATGTAGGCTTTTTTTTTTTTTTTTTTTTAGGTCTTGGTCTTCAGCCCTCTTATCCTGAT
TTATTCTCTCATTGGGGTCTCACTGTCTCTAGTATTTTAGCTACCACTTGATAAGGATGACTTCCAAATTTATATTCCCATTCCCAATAT
TTATTCCAAGACTCAGTTTTGCATTTCTGACTGCTAATCATCTATATATCAGTGTCCCAGTGGCCTCTTAATTGAGCATTATCAAAATCC
TGTGGTATTTATATGGTCCCAGTTATCCATCCCTGAAGTCTGTCAATTTTGATTTCTCTAAATTCCTTGCCATGACATCCTATATATGAT
CACATCTCTATACGGCTTAGCATTGTATTCCGATGCCCAGATGTCAAACTTGAAGCTCATTCTCTTATCAAAATTGTTCATGTATTCCTC
CTTTCCATTCTTATAGCTGTATTATTAGATCAGGTTTTTAATTCTGCTCAACCAATTATTACCACAGCCTGTTAAATGGAATCCCTACTC
CAAGGCTGACTGTTTCAATCTATCCTACACTTGGTTTCTAGCTCATTTACTTATACCATCTTTTGTTCAAATATATATTTTTTAATAACA
GACCTTTTTCTTCTAAAGAAATCTTTTGTAGAAGCAGCATATACGAAGCAGATAAAAGTAGGTTCAATGCGGTTGGAGTGAAGATGAGAA
TGCCACAGGCATCTTTCTTTCTAGGCCTCAGAGGTGCTGCATATGGAATGTCCATGGATCGCAGAGGGTTTTGAAGACCATGTTTTCAAA
AACACTGTCTTAACACTCTATTGTCATTGCTCTTTTCCCTCTTATTTCCTCTTTGTCTCTTCCCGACTTAGATCTAATTTTCAACAACCC
AGGAAATTATCTCATATGTTTGCATCTCTCAAGTTTCTTTTCTTTTTTCTTTCAGAGTCTTATTTTATCTAAATTTATGTAGAAAAAAAA
GCTTTGAATGTTGACTACATAGACATTACTACAATAAGCTTTTTGCCTTTCCCAAGACTCAAAATTGACACATCTTTGTTGATGTTTAAG
TTGAAATTCCAGCCAACTTTTTTTTGACTTTTATGTGAAGTTTAAAGTCTTTTCTTTGAAAAGCTTGCTTCCTCAATTTCAAAGATTTGT
CCTCTGATATATTTATAAACATCAATTTAATGCAGACATTCAAACCCTAAACCTTGAATAACTCTTATTTTATTTTGTCTTTGTTTACTT
CCATTAATTTTTTTTTCTTTCCCTCTCTTCCGCCTTTACAGCACCCACTTTTTCTTCCCCCCATGATGGCAAATATTGTTATAGTCCCCA
AGGCAGGGAACTTCTATTCAGACTGTAAAAGGAAATGTTGAAATCCATAGCTGTCCTGTCAACAGTAGTGGAATGAAAAGTCGTTGGATT
GTTTTGGCACTGGTTCTGAAGCAGGCATAATTGGCAAATTATTATAATACTGCTGCCCGAAAATCCCCATTTGCCTCAAGATAGTGGCAT
TTATTGGCAGAAGCCTCTGAAATGTCCAGCACATTCTTTTGAGTTACCATTTAAGGATCAGCCTGACAATCGACTTCTCTCTGCACATTT
GCCCCCTTTGTAACCTAAGCCAGACTGTTCCCAAATGACCTTCTAAAGGACACAGTGCACCATCATCAATGGAAACAGTTCAGAAAGGAT
GACAGGAGGGAGATGTTTCTTAGTTCTGAGAGCCAGTCTGTAACAATGGGATAAGCATTTAATGGAATCAAAGCTGTTTTGCATAAAGAG
TGAACTCAGAGACGACAAGAGGGTCTTTATGAATTCCCTTCACATTTTGTAAAAACTGTCATATATAGGCTATCCCCTTAATTGATAAAT
GGGATCTAGAAAGCGGTATTATGACCAGAGGGTGAGAAGATTTAGGAATTTGGATAGCAGTTCAAGATAAGAAAGAACTTCTTATAGTTA
TAAATTTTCAATGATGGAATGGGTTGCTTCTTTAAACAGTGAGCCCACCATCACTTGGTATGTTCAAGGAAAGACTAGATAAAGTCGATA
TTGTGAGAGGAATTGCTGTATGATACCGTTTGGAGAAATGATTGACATAATCTTTTAAGGCCGGTGACCCTATCATTTTCCAAATAATTG
TTGCTAGTACTTAGTTAATTAGACCCATTTTTTTCTTAGGAAAGAGTTGGATCAATCATGGGAGACCCTGAAAAATTTCCTTACCTTTCC
TAAGGTTTAATTTCCTCTTCTGCGAAATGGAGACAATTATATTACTTTTGCTTATTTCATAAAGATCTTGTGAGGATTCAATGAAATGAG
GTTAAATTCTTTTATTAAACAGAAAGTTTTGAGTATTTGCCTAGAGAGTGATGTGACTTTTGCAGCAGAAGGTGGGAAAACATCCAAGGG
AACTACATTTCCTCCAGAAATTGTTTCTTCATTACCATCGACCTACTGATTATGGTTTTCTCATTTTACACTTGGTGTTCTTACTTGGGA
TCTTTGTCCTTAAGCTCAACAGGGAGCCACAACCCAGGGGACCTATGTGTACACTTGGAGTTTTTATCAGACTATCATTTGAACTTACCA
CTACAGTTTAGCAAATGGCATGATGAGTTTGATTGATAATAGGAGTAGACGCAAGATACATTAAGTAGAGTACAAAGCATTTCATAACCA
AAATGTCATGGTTGGAGGTCTTCATTATTCGGTCTTTATCTCATTCAGGAATTTCCACTTGAAAAATCTCTGATAAGCTTTATTTCAGAA
ACTGCTTGAACAGCTCCACTGACAAATGCCTCACTATCTTCTGATACATCGTAGGCAGTTCTGAGGGTGAGAAAGTTCAAAGCAGATAGA
TGTTTTAACACAACAGGAGGACTTTTAAACAATCACCAGGACTCACTCCTCGGTGGTCAATTGGGCCTGTTTGGAGGCCTGACCTTTGGT
CATCTTAAGGTCATCTAAGGCAGAAAAGAGAAGCTCACTTATAAGTTGGCACTTCTGAATCATTTGCCTTGAGGTCCATTTTTTATTCAG
CCTTTGTTTAAACCTTCTTAGGAAGCCAGTTTGTAGAGTTCTGGGGATAAGAAGGCAGAAAAACCATGTCAATTCAGTGCTTTTATTTCA
CAGAAAATGAAGCAAAGGCCTAGAAACTAGAAAGACATTTCTCAAAAAGAAGATGGTGAACTTTTGGAAATACTGAGATTAGACTACATT
TTCCAATTTCTATCCCTAGCCCACTGCTCTTTCCAATATAATATCTGTATTCCATGGGAAAGACATGCCATCTGAATTGATGTATCGTAG
TTGTTGAGATAATTTTGAAATGAGAAAACAATAGGGCACAGTCGTTTGGGAAGAATTTCCAGAAATTGCCATCATTTTCTTAAAGGCTAA
GGACACTTATAGAGCTCTCCGATTTCCTATCTGATAAAAAAAGCCCAAACAAAGCTGCGGAAGCTGGCAGAGCCAGCAGATATTTTGTAA
GGCAGCTTCACCTCTGCTGGCATTTTGTGGGGCAGGAGAGGGGGAGGGCAAAGGTATTAAATTTAGGCTTAAAAGCTCCTCAGAAATTCT
TTACACACAAGAGACCAAGTTGGAGAAAAGAAGATGACTTGTGCCAAGGGGAAGAAAGAGAGAGACTAATGCCTGTGGTTTTCAAAGGTT
AACAACAACATAAAAAAGCCAAGGTATTTGCACAGGGATGAATGCTCATTGGCTCTTGGCCAACAATTATACAAGGGCTTGTGCCCACAT
CCTGTAGCTGTGGTTTAGGGACGCTGCTCATGAGTGACTTCTTATGCTTAGTGGCAGGAAACTTTAGTCACTGATGTGTAAACTCACCTT
TGGTCTGCACCTCCCACAACGTGCTCCGAAAGCAGTTAGGGGACTAGGCCTCTTGATTTCCTTGTAGATACCAGTTCCCCAGAAGCTAAG
GAAAAACTCTGAGGCCTTGGAGTTACTGAGAGTGGACCAATACTTGTCTTATTCTACCTGATTTTGGCAACTGCTTAGGGTTCTTCTGTA
TCCACAAAAAGGAATTATGATATCCTCTGCTAAACCCTCTCTTTAGCCTCAAAGCCCAAGACCAAAAAAAATGAGCCATATTTCATTGCA

>99842_99842_1_XXYLT1-TPRG1_XXYLT1_chr3_194877178_ENST00000310380_TPRG1_chr3_189028175_ENST00000345063_length(amino acids)=377AA_BP=261
MGLLRGGLPCARAMARLGAVRSHYCALLLAAALAVCAFYYLGSGRETFSSATKRLKEARAGAPAAPSPPALELARGSVAPAPGAKAKSLE
GGGAGPVDYHLLMMFTKAEHNAALQAKARVALRSLLRLAKFEAHEVLNLHFVSEEASREVAKGLLRELLPPAAGFKCKVIFHDVAVLTDK
LFPIVEAMQKHFSAGLGTYYSDSIFFLSVAMHQIMPKEILQIIQLDLDLKFKTNIRELFEEFDSFLPGAIIGIAREMQPVYRRQGEGLRI
YWGSPEEQSLLSRWNPWSTEVPYATFTEHPMKYTSEKFLEICKLSGFMSKLVPAIQNAHKNSTGSGRGKKLMVLTEPILIETYTGLMSFI

--------------------------------------------------------------
>99842_99842_2_XXYLT1-TPRG1_XXYLT1_chr3_194877178_ENST00000310380_TPRG1_chr3_189028175_ENST00000433971_length(transcript)=1484nt_BP=894nt
CCCCTTTCATGGCCGCCGCCTGGCGCCGGGGCTAAGTGGCCGCCGGCGTCCGGGTACCCGAGGGCTCTCCCGCGTTGCTGGCACCGCTGG
CGCCGCGGTCTCGTAGCGCATGGGCCTCCTCCGAGGCGGGCTCCCATGCGCTCGGGCCATGGCGCGCCTGGGCGCTGTGCGCTCCCACTA
CTGCGCCCTGCTGCTGGCCGCGGCGCTGGCCGTCTGCGCCTTCTACTACCTCGGCTCAGGCCGGGAGACCTTCTCCAGCGCCACCAAGAG
GCTGAAGGAGGCCCGCGCCGGGGCTCCCGCCGCGCCCTCGCCGCCCGCGCTGGAGCTAGCGCGGGGCTCCGTGGCGCCAGCCCCCGGCGC
GAAGGCCAAGAGCTTGGAGGGCGGCGGTGCCGGGCCGGTGGACTACCACCTGCTGATGATGTTCACCAAGGCGGAGCACAATGCCGCGCT
GCAGGCCAAGGCCCGCGTCGCGCTGCGCTCACTGCTGCGCCTCGCCAAGTTCGAGGCGCACGAGGTGCTTAACCTTCACTTCGTGAGCGA
GGAGGCCAGCCGCGAGGTGGCCAAGGGCCTGCTGCGGGAGCTCCTGCCGCCCGCCGCTGGCTTCAAGTGCAAGGTCATCTTCCACGATGT
TGCTGTGCTGACGGATAAGCTCTTCCCCATCGTGGAGGCCATGCAGAAGCACTTCAGTGCTGGCTTGGGAACCTACTACAGTGACTCCAT
CTTCTTCCTCTCGGTCGCCATGCATCAGATCATGCCCAAAGAGATCCTGCAGATCATTCAGCTGGACCTAGACCTGAAGTTTAAGACCAA
CATCCGGGAGTTGTTTGAGGAATTTGACAGTTTCCTGCCAGGCGCCATCATCGGCATAGCCCGGGAGATGCAGCCAGTTTACAGGAGACA
AGGAGAAGGCCTTAGGATCTACTGGGGGAGTCCGGAGGAGCAGTCTCTTCTGTCCCGCTGGAACCCATGGTCCACTGAAGTTCCTTATGC
TACTTTCACTGAGCATCCTATGAAATACACCAGTGAGAAATTCCTTGAAATTTGCAAGTTGTCTGGGTTCATGTCTAAGCTTGTTCCAGC
TATCCAGAATGCCCACAAGAATTCAACTGGATCTGGAAGAGGAAAGAAACTGATGGTGTTAACTGAACCCATTTTGATTGAGACCTACAC
AGGGCTGATGTCATTCATTGGAAACCGCAACAAACTTGGCTATTCCCTTGCCCGTGGGAGTATTGGTTTTTGAGAGTCTTTTTGGTACCA
TAAGCATATCATCCACAGATATGTCACTTTGAAAATTCCAGTTTGACCCACGCTATTTTTGGACTGAAACAATTAATTATTTTTAAATGA
CGCTTTATGATTTAGAAATTTAGTATTTCCGAAAATTTAAAAGCTTGATTGGACTGATAGATACACACTTTAGACCTCATACAAGAATAA

>99842_99842_2_XXYLT1-TPRG1_XXYLT1_chr3_194877178_ENST00000310380_TPRG1_chr3_189028175_ENST00000433971_length(amino acids)=377AA_BP=261
MGLLRGGLPCARAMARLGAVRSHYCALLLAAALAVCAFYYLGSGRETFSSATKRLKEARAGAPAAPSPPALELARGSVAPAPGAKAKSLE
GGGAGPVDYHLLMMFTKAEHNAALQAKARVALRSLLRLAKFEAHEVLNLHFVSEEASREVAKGLLRELLPPAAGFKCKVIFHDVAVLTDK
LFPIVEAMQKHFSAGLGTYYSDSIFFLSVAMHQIMPKEILQIIQLDLDLKFKTNIRELFEEFDSFLPGAIIGIAREMQPVYRRQGEGLRI
YWGSPEEQSLLSRWNPWSTEVPYATFTEHPMKYTSEKFLEICKLSGFMSKLVPAIQNAHKNSTGSGRGKKLMVLTEPILIETYTGLMSFI

--------------------------------------------------------------
>99842_99842_3_XXYLT1-TPRG1_XXYLT1_chr3_194877178_ENST00000355729_TPRG1_chr3_189028175_ENST00000345063_length(transcript)=5009nt_BP=176nt
ATGTGGCCACCTCGCTGCAAGGATCCAGGAAGGCAGAGTGCGGAGATCCTGCAGATCATTCAGCTGGACCTAGACCTGAAGTTTAAGACC
AACATCCGGGAGTTGTTTGAGGAATTTGACAGTTTCCTGCCAGGCGCCATCATCGGCATAGCCCGGGAGATGCAGCCAGTTTACAGGAGA
CAAGGAGAAGGCCTTAGGATCTACTGGGGGAGTCCGGAGGAGCAGTCTCTTCTGTCCCGCTGGAACCCATGGTCCACTGAAGTTCCTTAT
GCTACTTTCACTGAGCATCCTATGAAATACACCAGTGAGAAATTCCTTGAAATTTGCAAGTTGTCTGGGTTCATGTCTAAGCTTGTTCCA
GCTATCCAGAATGCCCACAAGAATTCAACTGGATCTGGAAGAGGAAAGAAACTGATGGTGTTAACTGAACCCATTTTGATTGAGACCTAC
ACAGGGCTGATGTCATTCATTGGAAACCGCAACAAACTTGGCTATTCCCTTGCCCGTGGGAGTATTGGTTTTTGAGAGTCTTTTTGGTAC
CATAAGCATATCATCCACAGATATGTCACTTTGAAAATTCCAGTTTGACCCACGCTATTTTTGGACTGAAACAATTAATTATTTTTAAAT
GACGCTTTATGATTTAGAAATTTAGTATTTCCGAAAATTTAAAAGCTTGATTGGACTGATAGATACACACTTTAGACCTCATACAAGAAT
AATCAAATTTTCTTAAAACTAGAAAATAAATGCTGCTGAGCCTATCAAATACTGTTATCAAATGAGTGCCTGATCATCAACTCAGGAAAG
AAGACTCTAAGTCCTGTTGCTTCAGCTCTCTAAATGTAGGCTTTTTTTTTTTTTTTTTTTTAGGTCTTGGTCTTCAGCCCTCTTATCCTG
ATTTATTCTCTCATTGGGGTCTCACTGTCTCTAGTATTTTAGCTACCACTTGATAAGGATGACTTCCAAATTTATATTCCCATTCCCAAT
ATTTATTCCAAGACTCAGTTTTGCATTTCTGACTGCTAATCATCTATATATCAGTGTCCCAGTGGCCTCTTAATTGAGCATTATCAAAAT
CCTGTGGTATTTATATGGTCCCAGTTATCCATCCCTGAAGTCTGTCAATTTTGATTTCTCTAAATTCCTTGCCATGACATCCTATATATG
ATCACATCTCTATACGGCTTAGCATTGTATTCCGATGCCCAGATGTCAAACTTGAAGCTCATTCTCTTATCAAAATTGTTCATGTATTCC
TCCTTTCCATTCTTATAGCTGTATTATTAGATCAGGTTTTTAATTCTGCTCAACCAATTATTACCACAGCCTGTTAAATGGAATCCCTAC
TCCAAGGCTGACTGTTTCAATCTATCCTACACTTGGTTTCTAGCTCATTTACTTATACCATCTTTTGTTCAAATATATATTTTTTAATAA
CAGACCTTTTTCTTCTAAAGAAATCTTTTGTAGAAGCAGCATATACGAAGCAGATAAAAGTAGGTTCAATGCGGTTGGAGTGAAGATGAG
AATGCCACAGGCATCTTTCTTTCTAGGCCTCAGAGGTGCTGCATATGGAATGTCCATGGATCGCAGAGGGTTTTGAAGACCATGTTTTCA
AAAACACTGTCTTAACACTCTATTGTCATTGCTCTTTTCCCTCTTATTTCCTCTTTGTCTCTTCCCGACTTAGATCTAATTTTCAACAAC
CCAGGAAATTATCTCATATGTTTGCATCTCTCAAGTTTCTTTTCTTTTTTCTTTCAGAGTCTTATTTTATCTAAATTTATGTAGAAAAAA
AAGCTTTGAATGTTGACTACATAGACATTACTACAATAAGCTTTTTGCCTTTCCCAAGACTCAAAATTGACACATCTTTGTTGATGTTTA
AGTTGAAATTCCAGCCAACTTTTTTTTGACTTTTATGTGAAGTTTAAAGTCTTTTCTTTGAAAAGCTTGCTTCCTCAATTTCAAAGATTT
GTCCTCTGATATATTTATAAACATCAATTTAATGCAGACATTCAAACCCTAAACCTTGAATAACTCTTATTTTATTTTGTCTTTGTTTAC
TTCCATTAATTTTTTTTTCTTTCCCTCTCTTCCGCCTTTACAGCACCCACTTTTTCTTCCCCCCATGATGGCAAATATTGTTATAGTCCC
CAAGGCAGGGAACTTCTATTCAGACTGTAAAAGGAAATGTTGAAATCCATAGCTGTCCTGTCAACAGTAGTGGAATGAAAAGTCGTTGGA
TTGTTTTGGCACTGGTTCTGAAGCAGGCATAATTGGCAAATTATTATAATACTGCTGCCCGAAAATCCCCATTTGCCTCAAGATAGTGGC
ATTTATTGGCAGAAGCCTCTGAAATGTCCAGCACATTCTTTTGAGTTACCATTTAAGGATCAGCCTGACAATCGACTTCTCTCTGCACAT
TTGCCCCCTTTGTAACCTAAGCCAGACTGTTCCCAAATGACCTTCTAAAGGACACAGTGCACCATCATCAATGGAAACAGTTCAGAAAGG
ATGACAGGAGGGAGATGTTTCTTAGTTCTGAGAGCCAGTCTGTAACAATGGGATAAGCATTTAATGGAATCAAAGCTGTTTTGCATAAAG
AGTGAACTCAGAGACGACAAGAGGGTCTTTATGAATTCCCTTCACATTTTGTAAAAACTGTCATATATAGGCTATCCCCTTAATTGATAA
ATGGGATCTAGAAAGCGGTATTATGACCAGAGGGTGAGAAGATTTAGGAATTTGGATAGCAGTTCAAGATAAGAAAGAACTTCTTATAGT
TATAAATTTTCAATGATGGAATGGGTTGCTTCTTTAAACAGTGAGCCCACCATCACTTGGTATGTTCAAGGAAAGACTAGATAAAGTCGA
TATTGTGAGAGGAATTGCTGTATGATACCGTTTGGAGAAATGATTGACATAATCTTTTAAGGCCGGTGACCCTATCATTTTCCAAATAAT
TGTTGCTAGTACTTAGTTAATTAGACCCATTTTTTTCTTAGGAAAGAGTTGGATCAATCATGGGAGACCCTGAAAAATTTCCTTACCTTT
CCTAAGGTTTAATTTCCTCTTCTGCGAAATGGAGACAATTATATTACTTTTGCTTATTTCATAAAGATCTTGTGAGGATTCAATGAAATG
AGGTTAAATTCTTTTATTAAACAGAAAGTTTTGAGTATTTGCCTAGAGAGTGATGTGACTTTTGCAGCAGAAGGTGGGAAAACATCCAAG
GGAACTACATTTCCTCCAGAAATTGTTTCTTCATTACCATCGACCTACTGATTATGGTTTTCTCATTTTACACTTGGTGTTCTTACTTGG
GATCTTTGTCCTTAAGCTCAACAGGGAGCCACAACCCAGGGGACCTATGTGTACACTTGGAGTTTTTATCAGACTATCATTTGAACTTAC
CACTACAGTTTAGCAAATGGCATGATGAGTTTGATTGATAATAGGAGTAGACGCAAGATACATTAAGTAGAGTACAAAGCATTTCATAAC
CAAAATGTCATGGTTGGAGGTCTTCATTATTCGGTCTTTATCTCATTCAGGAATTTCCACTTGAAAAATCTCTGATAAGCTTTATTTCAG
AAACTGCTTGAACAGCTCCACTGACAAATGCCTCACTATCTTCTGATACATCGTAGGCAGTTCTGAGGGTGAGAAAGTTCAAAGCAGATA
GATGTTTTAACACAACAGGAGGACTTTTAAACAATCACCAGGACTCACTCCTCGGTGGTCAATTGGGCCTGTTTGGAGGCCTGACCTTTG
GTCATCTTAAGGTCATCTAAGGCAGAAAAGAGAAGCTCACTTATAAGTTGGCACTTCTGAATCATTTGCCTTGAGGTCCATTTTTTATTC
AGCCTTTGTTTAAACCTTCTTAGGAAGCCAGTTTGTAGAGTTCTGGGGATAAGAAGGCAGAAAAACCATGTCAATTCAGTGCTTTTATTT
CACAGAAAATGAAGCAAAGGCCTAGAAACTAGAAAGACATTTCTCAAAAAGAAGATGGTGAACTTTTGGAAATACTGAGATTAGACTACA
TTTTCCAATTTCTATCCCTAGCCCACTGCTCTTTCCAATATAATATCTGTATTCCATGGGAAAGACATGCCATCTGAATTGATGTATCGT
AGTTGTTGAGATAATTTTGAAATGAGAAAACAATAGGGCACAGTCGTTTGGGAAGAATTTCCAGAAATTGCCATCATTTTCTTAAAGGCT
AAGGACACTTATAGAGCTCTCCGATTTCCTATCTGATAAAAAAAGCCCAAACAAAGCTGCGGAAGCTGGCAGAGCCAGCAGATATTTTGT
AAGGCAGCTTCACCTCTGCTGGCATTTTGTGGGGCAGGAGAGGGGGAGGGCAAAGGTATTAAATTTAGGCTTAAAAGCTCCTCAGAAATT
CTTTACACACAAGAGACCAAGTTGGAGAAAAGAAGATGACTTGTGCCAAGGGGAAGAAAGAGAGAGACTAATGCCTGTGGTTTTCAAAGG
TTAACAACAACATAAAAAAGCCAAGGTATTTGCACAGGGATGAATGCTCATTGGCTCTTGGCCAACAATTATACAAGGGCTTGTGCCCAC
ATCCTGTAGCTGTGGTTTAGGGACGCTGCTCATGAGTGACTTCTTATGCTTAGTGGCAGGAAACTTTAGTCACTGATGTGTAAACTCACC
TTTGGTCTGCACCTCCCACAACGTGCTCCGAAAGCAGTTAGGGGACTAGGCCTCTTGATTTCCTTGTAGATACCAGTTCCCCAGAAGCTA
AGGAAAAACTCTGAGGCCTTGGAGTTACTGAGAGTGGACCAATACTTGTCTTATTCTACCTGATTTTGGCAACTGCTTAGGGTTCTTCTG
TATCCACAAAAAGGAATTATGATATCCTCTGCTAAACCCTCTCTTTAGCCTCAAAGCCCAAGACCAAAAAAAATGAGCCATATTTCATTG

>99842_99842_3_XXYLT1-TPRG1_XXYLT1_chr3_194877178_ENST00000355729_TPRG1_chr3_189028175_ENST00000345063_length(amino acids)=174AA_BP=58
MWPPRCKDPGRQSAEILQIIQLDLDLKFKTNIRELFEEFDSFLPGAIIGIAREMQPVYRRQGEGLRIYWGSPEEQSLLSRWNPWSTEVPY

--------------------------------------------------------------
>99842_99842_4_XXYLT1-TPRG1_XXYLT1_chr3_194877178_ENST00000355729_TPRG1_chr3_189028175_ENST00000433971_length(transcript)=766nt_BP=176nt
ATGTGGCCACCTCGCTGCAAGGATCCAGGAAGGCAGAGTGCGGAGATCCTGCAGATCATTCAGCTGGACCTAGACCTGAAGTTTAAGACC
AACATCCGGGAGTTGTTTGAGGAATTTGACAGTTTCCTGCCAGGCGCCATCATCGGCATAGCCCGGGAGATGCAGCCAGTTTACAGGAGA
CAAGGAGAAGGCCTTAGGATCTACTGGGGGAGTCCGGAGGAGCAGTCTCTTCTGTCCCGCTGGAACCCATGGTCCACTGAAGTTCCTTAT
GCTACTTTCACTGAGCATCCTATGAAATACACCAGTGAGAAATTCCTTGAAATTTGCAAGTTGTCTGGGTTCATGTCTAAGCTTGTTCCA
GCTATCCAGAATGCCCACAAGAATTCAACTGGATCTGGAAGAGGAAAGAAACTGATGGTGTTAACTGAACCCATTTTGATTGAGACCTAC
ACAGGGCTGATGTCATTCATTGGAAACCGCAACAAACTTGGCTATTCCCTTGCCCGTGGGAGTATTGGTTTTTGAGAGTCTTTTTGGTAC
CATAAGCATATCATCCACAGATATGTCACTTTGAAAATTCCAGTTTGACCCACGCTATTTTTGGACTGAAACAATTAATTATTTTTAAAT
GACGCTTTATGATTTAGAAATTTAGTATTTCCGAAAATTTAAAAGCTTGATTGGACTGATAGATACACACTTTAGACCTCATACAAGAAT

>99842_99842_4_XXYLT1-TPRG1_XXYLT1_chr3_194877178_ENST00000355729_TPRG1_chr3_189028175_ENST00000433971_length(amino acids)=174AA_BP=58
MWPPRCKDPGRQSAEILQIIQLDLDLKFKTNIRELFEEFDSFLPGAIIGIAREMQPVYRRQGEGLRIYWGSPEEQSLLSRWNPWSTEVPY

--------------------------------------------------------------
>99842_99842_5_XXYLT1-TPRG1_XXYLT1_chr3_194877178_ENST00000429994_TPRG1_chr3_189028175_ENST00000345063_length(transcript)=5263nt_BP=430nt
GTGAGAGTCAGTGAGCTCTCAGGAGATCTGCTGTTTGAAAGTGTGTAGCGCTTCCCCCTTCTCTCTCTCTGTCCTGCTGCACTATGGTGA
GATGTGTCCCTTCCGCCGTGATTGTGTGTTTCCTGAGGCCTCCCCAGCCAGGCAGAACTGTCATCTTCCACGATGTTGCTGTGCTGACGG
ATAAGCTCTTCCCCATCGTGGAGGCCATGCAGAAGCACTTCAGTGCTGGCTTGGGAACCTACTACAGTGACTCCATCTTCTTCCTCTCGG
TCGCCATGCATCAGATCATGCCCAAAGAGATCCTGCAGATCATTCAGCTGGACCTAGACCTGAAGTTTAAGACCAACATCCGGGAGTTGT
TTGAGGAATTTGACAGTTTCCTGCCAGGCGCCATCATCGGCATAGCCCGGGAGATGCAGCCAGTTTACAGGAGACAAGGAGAAGGCCTTA
GGATCTACTGGGGGAGTCCGGAGGAGCAGTCTCTTCTGTCCCGCTGGAACCCATGGTCCACTGAAGTTCCTTATGCTACTTTCACTGAGC
ATCCTATGAAATACACCAGTGAGAAATTCCTTGAAATTTGCAAGTTGTCTGGGTTCATGTCTAAGCTTGTTCCAGCTATCCAGAATGCCC
ACAAGAATTCAACTGGATCTGGAAGAGGAAAGAAACTGATGGTGTTAACTGAACCCATTTTGATTGAGACCTACACAGGGCTGATGTCAT
TCATTGGAAACCGCAACAAACTTGGCTATTCCCTTGCCCGTGGGAGTATTGGTTTTTGAGAGTCTTTTTGGTACCATAAGCATATCATCC
ACAGATATGTCACTTTGAAAATTCCAGTTTGACCCACGCTATTTTTGGACTGAAACAATTAATTATTTTTAAATGACGCTTTATGATTTA
GAAATTTAGTATTTCCGAAAATTTAAAAGCTTGATTGGACTGATAGATACACACTTTAGACCTCATACAAGAATAATCAAATTTTCTTAA
AACTAGAAAATAAATGCTGCTGAGCCTATCAAATACTGTTATCAAATGAGTGCCTGATCATCAACTCAGGAAAGAAGACTCTAAGTCCTG
TTGCTTCAGCTCTCTAAATGTAGGCTTTTTTTTTTTTTTTTTTTTAGGTCTTGGTCTTCAGCCCTCTTATCCTGATTTATTCTCTCATTG
GGGTCTCACTGTCTCTAGTATTTTAGCTACCACTTGATAAGGATGACTTCCAAATTTATATTCCCATTCCCAATATTTATTCCAAGACTC
AGTTTTGCATTTCTGACTGCTAATCATCTATATATCAGTGTCCCAGTGGCCTCTTAATTGAGCATTATCAAAATCCTGTGGTATTTATAT
GGTCCCAGTTATCCATCCCTGAAGTCTGTCAATTTTGATTTCTCTAAATTCCTTGCCATGACATCCTATATATGATCACATCTCTATACG
GCTTAGCATTGTATTCCGATGCCCAGATGTCAAACTTGAAGCTCATTCTCTTATCAAAATTGTTCATGTATTCCTCCTTTCCATTCTTAT
AGCTGTATTATTAGATCAGGTTTTTAATTCTGCTCAACCAATTATTACCACAGCCTGTTAAATGGAATCCCTACTCCAAGGCTGACTGTT
TCAATCTATCCTACACTTGGTTTCTAGCTCATTTACTTATACCATCTTTTGTTCAAATATATATTTTTTAATAACAGACCTTTTTCTTCT
AAAGAAATCTTTTGTAGAAGCAGCATATACGAAGCAGATAAAAGTAGGTTCAATGCGGTTGGAGTGAAGATGAGAATGCCACAGGCATCT
TTCTTTCTAGGCCTCAGAGGTGCTGCATATGGAATGTCCATGGATCGCAGAGGGTTTTGAAGACCATGTTTTCAAAAACACTGTCTTAAC
ACTCTATTGTCATTGCTCTTTTCCCTCTTATTTCCTCTTTGTCTCTTCCCGACTTAGATCTAATTTTCAACAACCCAGGAAATTATCTCA
TATGTTTGCATCTCTCAAGTTTCTTTTCTTTTTTCTTTCAGAGTCTTATTTTATCTAAATTTATGTAGAAAAAAAAGCTTTGAATGTTGA
CTACATAGACATTACTACAATAAGCTTTTTGCCTTTCCCAAGACTCAAAATTGACACATCTTTGTTGATGTTTAAGTTGAAATTCCAGCC
AACTTTTTTTTGACTTTTATGTGAAGTTTAAAGTCTTTTCTTTGAAAAGCTTGCTTCCTCAATTTCAAAGATTTGTCCTCTGATATATTT
ATAAACATCAATTTAATGCAGACATTCAAACCCTAAACCTTGAATAACTCTTATTTTATTTTGTCTTTGTTTACTTCCATTAATTTTTTT
TTCTTTCCCTCTCTTCCGCCTTTACAGCACCCACTTTTTCTTCCCCCCATGATGGCAAATATTGTTATAGTCCCCAAGGCAGGGAACTTC
TATTCAGACTGTAAAAGGAAATGTTGAAATCCATAGCTGTCCTGTCAACAGTAGTGGAATGAAAAGTCGTTGGATTGTTTTGGCACTGGT
TCTGAAGCAGGCATAATTGGCAAATTATTATAATACTGCTGCCCGAAAATCCCCATTTGCCTCAAGATAGTGGCATTTATTGGCAGAAGC
CTCTGAAATGTCCAGCACATTCTTTTGAGTTACCATTTAAGGATCAGCCTGACAATCGACTTCTCTCTGCACATTTGCCCCCTTTGTAAC
CTAAGCCAGACTGTTCCCAAATGACCTTCTAAAGGACACAGTGCACCATCATCAATGGAAACAGTTCAGAAAGGATGACAGGAGGGAGAT
GTTTCTTAGTTCTGAGAGCCAGTCTGTAACAATGGGATAAGCATTTAATGGAATCAAAGCTGTTTTGCATAAAGAGTGAACTCAGAGACG
ACAAGAGGGTCTTTATGAATTCCCTTCACATTTTGTAAAAACTGTCATATATAGGCTATCCCCTTAATTGATAAATGGGATCTAGAAAGC
GGTATTATGACCAGAGGGTGAGAAGATTTAGGAATTTGGATAGCAGTTCAAGATAAGAAAGAACTTCTTATAGTTATAAATTTTCAATGA
TGGAATGGGTTGCTTCTTTAAACAGTGAGCCCACCATCACTTGGTATGTTCAAGGAAAGACTAGATAAAGTCGATATTGTGAGAGGAATT
GCTGTATGATACCGTTTGGAGAAATGATTGACATAATCTTTTAAGGCCGGTGACCCTATCATTTTCCAAATAATTGTTGCTAGTACTTAG
TTAATTAGACCCATTTTTTTCTTAGGAAAGAGTTGGATCAATCATGGGAGACCCTGAAAAATTTCCTTACCTTTCCTAAGGTTTAATTTC
CTCTTCTGCGAAATGGAGACAATTATATTACTTTTGCTTATTTCATAAAGATCTTGTGAGGATTCAATGAAATGAGGTTAAATTCTTTTA
TTAAACAGAAAGTTTTGAGTATTTGCCTAGAGAGTGATGTGACTTTTGCAGCAGAAGGTGGGAAAACATCCAAGGGAACTACATTTCCTC
CAGAAATTGTTTCTTCATTACCATCGACCTACTGATTATGGTTTTCTCATTTTACACTTGGTGTTCTTACTTGGGATCTTTGTCCTTAAG
CTCAACAGGGAGCCACAACCCAGGGGACCTATGTGTACACTTGGAGTTTTTATCAGACTATCATTTGAACTTACCACTACAGTTTAGCAA
ATGGCATGATGAGTTTGATTGATAATAGGAGTAGACGCAAGATACATTAAGTAGAGTACAAAGCATTTCATAACCAAAATGTCATGGTTG
GAGGTCTTCATTATTCGGTCTTTATCTCATTCAGGAATTTCCACTTGAAAAATCTCTGATAAGCTTTATTTCAGAAACTGCTTGAACAGC
TCCACTGACAAATGCCTCACTATCTTCTGATACATCGTAGGCAGTTCTGAGGGTGAGAAAGTTCAAAGCAGATAGATGTTTTAACACAAC
AGGAGGACTTTTAAACAATCACCAGGACTCACTCCTCGGTGGTCAATTGGGCCTGTTTGGAGGCCTGACCTTTGGTCATCTTAAGGTCAT
CTAAGGCAGAAAAGAGAAGCTCACTTATAAGTTGGCACTTCTGAATCATTTGCCTTGAGGTCCATTTTTTATTCAGCCTTTGTTTAAACC
TTCTTAGGAAGCCAGTTTGTAGAGTTCTGGGGATAAGAAGGCAGAAAAACCATGTCAATTCAGTGCTTTTATTTCACAGAAAATGAAGCA
AAGGCCTAGAAACTAGAAAGACATTTCTCAAAAAGAAGATGGTGAACTTTTGGAAATACTGAGATTAGACTACATTTTCCAATTTCTATC
CCTAGCCCACTGCTCTTTCCAATATAATATCTGTATTCCATGGGAAAGACATGCCATCTGAATTGATGTATCGTAGTTGTTGAGATAATT
TTGAAATGAGAAAACAATAGGGCACAGTCGTTTGGGAAGAATTTCCAGAAATTGCCATCATTTTCTTAAAGGCTAAGGACACTTATAGAG
CTCTCCGATTTCCTATCTGATAAAAAAAGCCCAAACAAAGCTGCGGAAGCTGGCAGAGCCAGCAGATATTTTGTAAGGCAGCTTCACCTC
TGCTGGCATTTTGTGGGGCAGGAGAGGGGGAGGGCAAAGGTATTAAATTTAGGCTTAAAAGCTCCTCAGAAATTCTTTACACACAAGAGA
CCAAGTTGGAGAAAAGAAGATGACTTGTGCCAAGGGGAAGAAAGAGAGAGACTAATGCCTGTGGTTTTCAAAGGTTAACAACAACATAAA
AAAGCCAAGGTATTTGCACAGGGATGAATGCTCATTGGCTCTTGGCCAACAATTATACAAGGGCTTGTGCCCACATCCTGTAGCTGTGGT
TTAGGGACGCTGCTCATGAGTGACTTCTTATGCTTAGTGGCAGGAAACTTTAGTCACTGATGTGTAAACTCACCTTTGGTCTGCACCTCC
CACAACGTGCTCCGAAAGCAGTTAGGGGACTAGGCCTCTTGATTTCCTTGTAGATACCAGTTCCCCAGAAGCTAAGGAAAAACTCTGAGG
CCTTGGAGTTACTGAGAGTGGACCAATACTTGTCTTATTCTACCTGATTTTGGCAACTGCTTAGGGTTCTTCTGTATCCACAAAAAGGAA
TTATGATATCCTCTGCTAAACCCTCTCTTTAGCCTCAAAGCCCAAGACCAAAAAAAATGAGCCATATTTCATTGCAGGCCTGCTGCCAAT

>99842_99842_5_XXYLT1-TPRG1_XXYLT1_chr3_194877178_ENST00000429994_TPRG1_chr3_189028175_ENST00000345063_length(amino acids)=236AA_BP=10
MSCCTMVRCVPSAVIVCFLRPPQPGRTVIFHDVAVLTDKLFPIVEAMQKHFSAGLGTYYSDSIFFLSVAMHQIMPKEILQIIQLDLDLKF
KTNIRELFEEFDSFLPGAIIGIAREMQPVYRRQGEGLRIYWGSPEEQSLLSRWNPWSTEVPYATFTEHPMKYTSEKFLEICKLSGFMSKL

--------------------------------------------------------------
>99842_99842_6_XXYLT1-TPRG1_XXYLT1_chr3_194877178_ENST00000429994_TPRG1_chr3_189028175_ENST00000433971_length(transcript)=1020nt_BP=430nt
GTGAGAGTCAGTGAGCTCTCAGGAGATCTGCTGTTTGAAAGTGTGTAGCGCTTCCCCCTTCTCTCTCTCTGTCCTGCTGCACTATGGTGA
GATGTGTCCCTTCCGCCGTGATTGTGTGTTTCCTGAGGCCTCCCCAGCCAGGCAGAACTGTCATCTTCCACGATGTTGCTGTGCTGACGG
ATAAGCTCTTCCCCATCGTGGAGGCCATGCAGAAGCACTTCAGTGCTGGCTTGGGAACCTACTACAGTGACTCCATCTTCTTCCTCTCGG
TCGCCATGCATCAGATCATGCCCAAAGAGATCCTGCAGATCATTCAGCTGGACCTAGACCTGAAGTTTAAGACCAACATCCGGGAGTTGT
TTGAGGAATTTGACAGTTTCCTGCCAGGCGCCATCATCGGCATAGCCCGGGAGATGCAGCCAGTTTACAGGAGACAAGGAGAAGGCCTTA
GGATCTACTGGGGGAGTCCGGAGGAGCAGTCTCTTCTGTCCCGCTGGAACCCATGGTCCACTGAAGTTCCTTATGCTACTTTCACTGAGC
ATCCTATGAAATACACCAGTGAGAAATTCCTTGAAATTTGCAAGTTGTCTGGGTTCATGTCTAAGCTTGTTCCAGCTATCCAGAATGCCC
ACAAGAATTCAACTGGATCTGGAAGAGGAAAGAAACTGATGGTGTTAACTGAACCCATTTTGATTGAGACCTACACAGGGCTGATGTCAT
TCATTGGAAACCGCAACAAACTTGGCTATTCCCTTGCCCGTGGGAGTATTGGTTTTTGAGAGTCTTTTTGGTACCATAAGCATATCATCC
ACAGATATGTCACTTTGAAAATTCCAGTTTGACCCACGCTATTTTTGGACTGAAACAATTAATTATTTTTAAATGACGCTTTATGATTTA
GAAATTTAGTATTTCCGAAAATTTAAAAGCTTGATTGGACTGATAGATACACACTTTAGACCTCATACAAGAATAATCAAATTTTCTTAA

>99842_99842_6_XXYLT1-TPRG1_XXYLT1_chr3_194877178_ENST00000429994_TPRG1_chr3_189028175_ENST00000433971_length(amino acids)=236AA_BP=10
MSCCTMVRCVPSAVIVCFLRPPQPGRTVIFHDVAVLTDKLFPIVEAMQKHFSAGLGTYYSDSIFFLSVAMHQIMPKEILQIIQLDLDLKF
KTNIRELFEEFDSFLPGAIIGIAREMQPVYRRQGEGLRIYWGSPEEQSLLSRWNPWSTEVPYATFTEHPMKYTSEKFLEICKLSGFMSKL

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for XXYLT1-TPRG1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneXXYLT1chr3:194877178chr3:189028175ENST00000310380-34263_266261.6666666666667394.0target proteins
HgeneXXYLT1chr3:194877178chr3:189028175ENST00000355729-23263_26658.666666666666664191.0target proteins
HgeneXXYLT1chr3:194877178chr3:189028175ENST00000356740-12263_2660.0188.0target proteins
HgeneXXYLT1chr3:194877178chr3:189028175ENST00000437101-45263_26658.666666666666664191.0target proteins


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for XXYLT1-TPRG1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for XXYLT1-TPRG1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource