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Center for Computational Systems Medicine
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Fusion Gene and Fusion Protein Summary

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Fusion Amino Acid Sequences (multiple BPs and multiple gene isoforms)

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Fusion Protein Breakpoint Sequences - (for the Screening of the FusionNeoAntigens)

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Potential FusionNeoAntigens in HLA I - (netMHCpan v4.1 + deepHLApan v1.1)

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Potential FusionNeoAntigens in HLA II - (netMHCIIpan v4.1)

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Fusion Breakpoint 14 AA Peptide Structure - (RoseTTAFold)

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Filtering FusionNeoAntigens Through Checking the Interaction with HLAs in 3D - (Glide)

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Vaccine Design for the FusionNeoAntigens (RNA/protein sequences)

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Potential target of CAR-T therapy development

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Information on the samples that have these potential fusion neoantigens

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Fusion Protein Targeting Drugs - (Manual Curation)

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Fusion Protein Related diseases - (Manual Curation)

Fusion Protein:KANSL1-AARS

Fusion Gene and Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: KANSL1-AARS
FusionPDB ID: 41114
FusionGDB2.0 ID: 42298
HgeneTgene
Gene symbol

KANSL1

AARS

Gene ID

284058

16

Gene nameKAT8 regulatory NSL complex subunit 1alanyl-tRNA synthetase 1
SynonymsCENP-36|KDVS|KIAA1267|MSL1v1|NSL1|hMSL1v1AARS|CMT2N|EIEE29
Cytomap

17q21.31

16q22.1

Type of geneprotein-codingprotein-coding
DescriptionKAT8 regulatory NSL complex subunit 1MLL1/MLL complex subunit KANSL1MSL1 homolog 1NSL complex protein NSL1centromere protein 36male-specific lethal 1 homolognon-specific lethal 1 homologalanine--tRNA ligase, cytoplasmicalaRSalanine tRNA ligase 1, cytoplasmicalanyl-tRNA synthetase, cytoplasmicrenal carcinoma antigen NY-REN-42
Modification date2020032720200328
UniProtAcc

A0AUZ9

Main function of 5'-partner protein:

Q9BTE6

Main function of 5'-partner protein: FUNCTION: Functions in trans to edit the amino acid moiety from incorrectly charged tRNA(Ala). {ECO:0000250}.
Ensembl transtripts involved in fusion geneENST idsENST00000262419, ENST00000432791, 
ENST00000572904, ENST00000574590, 
ENST00000575318, ENST00000393476, 
ENST00000576248, 
ENST00000564359, 
ENST00000261772, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score34 X 33 X 14=1570812 X 12 X 5=720
# samples 4715
** MAII scorelog2(47/15708*10)=-5.0626949361014
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(15/720*10)=-2.26303440583379
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Fusion gene context

PubMed: KANSL1 [Title/Abstract] AND AARS [Title/Abstract] AND fusion [Title/Abstract]

Fusion neoantigen context

PubMed: KANSL1 [Title/Abstract] AND AARS [Title/Abstract] AND neoantigen [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)KANSL1(44143903)-AARS(70295060), # samples:2
Anticipated loss of major functional domain due to fusion event.KANSL1-AARS seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
KANSL1-AARS seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
KANSL1-AARS seems lost the major protein functional domain in Hgene partner, which is a epigenetic factor due to the frame-shifted ORF.
KANSL1-AARS seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
KANSL1-AARS seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneKANSL1

GO:0043981

histone H4-K5 acetylation

20018852

HgeneKANSL1

GO:0043982

histone H4-K8 acetylation

20018852

HgeneKANSL1

GO:0043984

histone H4-K16 acetylation

20018852

TgeneAARS

GO:0006419

alanyl-tRNA aminoacylation

27622773|28493438



check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:44143903/chr16:70295060)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonRetention analysis results of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features, are available here.

check buttonFusion gene breakpoints across KANSL1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across AARS (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


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Fusion Amino Acid Sequences


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)
ENST00000574590KANSL1chr1744143903-ENST00000261772AARSchr1670295060-3737207522733101027
ENST00000575318KANSL1chr1744143903-ENST00000261772AARSchr1670295060-354418823431171027
ENST00000432791KANSL1chr1744143903-ENST00000261772AARSchr1670295060-359519338531681027

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000574590ENST00000261772KANSL1chr1744143903-AARSchr1670295060-0.0027333650.99726665
ENST00000575318ENST00000261772KANSL1chr1744143903-AARSchr1670295060-0.0026733980.9973266
ENST00000432791ENST00000261772KANSL1chr1744143903-AARSchr1670295060-0.0028407590.99715924

check button Predicted full-length fusion amino acid sequences. For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among all the predicted ones.

Get the fusion protein sequences from here.

Fusion protein sequence information is available in the fasta format.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

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Fusion Protein Breakpoint Sequences for KANSL1-AARS

check button +/-13 AA sequence from the breakpoints of the fusion protein sequences.
HgeneHchrHbpTgeneTchrTbpLength(fusion protein)BP in fusion proteinPeptide
KANSL1chr1744143903AARSchr16702950601882616LVRPNSIVPLSKKKTEFTVKNAQVRG
KANSL1chr1744143903AARSchr16702950601933616LVRPNSIVPLSKKKTEFTVKNAQVRG
KANSL1chr1744143903AARSchr16702950602075616LVRPNSIVPLSKKKTEFTVKNAQVRG

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Potential FusionNeoAntigen Information of KANSL1-AARS in HLA I

check button Multiple sequence alignments of the potential FusionNeoAntigens per fusion breakpoints. If the MSA is empty, then it means that there were predicted fusion neoantigens in this fusion breakpoint, but those predicted fusion neoantigens were not across the breakpoint, which is not fusion-specific.
KANSL1-AARS_44143903_70295060.msa

check button Potential FusionNeoAntigen Information
* We used NetMHCpan v4.1 (%rank<0.5) and deepHLApan v1.1 (immunogenic score>0.5)
Fusion geneHchrHbpTgeneTchrTbpHLA IFusionNeoAntigen peptideBinding scoreImmunogenic scoreNeoantigen start (at BP 13)Neoantigen end (at BP 13)
KANSL1-AARSchr1744143903chr16702950601933HLA-A30:08SIVPLSKKK0.88830.5949514
KANSL1-AARSchr1744143903chr16702950601933HLA-B08:01VPLSKKKTEF0.97770.6638717
KANSL1-AARSchr1744143903chr16702950601933HLA-B42:02VPLSKKKTEF0.97780.6843717
KANSL1-AARSchr1744143903chr16702950601933HLA-B42:01VPLSKKKTEF0.97520.6754717
KANSL1-AARSchr1744143903chr16702950601933HLA-C16:01LSKKKTEF0.92520.9901917
KANSL1-AARSchr1744143903chr16702950601933HLA-A30:01SIVPLSKKK0.87550.7188514
KANSL1-AARSchr1744143903chr16702950601933HLA-B08:18VPLSKKKTEF0.97770.6638717
KANSL1-AARSchr1744143903chr16702950601933HLA-B08:12VPLSKKKTEF0.80860.8363717

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Potential FusionNeoAntigen Information of KANSL1-AARS in HLA II

check button Multiple sequence alignments of the potential FusionNeoAntigens per fusion breakpoints. If the MSA is empty, then it means that there were predicted fusion neoantigens in this fusion breakpoint, but those predicted fusion neoantigens were not across the breakpoint, which is not fusion-specific.
KANSL1-AARS_44143903_70295060.msa

check button Potential FusionNeoAntigen Information
* We used NetMHCIIpan v4.1 (%rank<0.5).
Fusion geneHchrHbpTgeneTchrTbpHLA IIFusionNeoAntigen peptideNeoantigen start (at BP 13)Neoantigen end (at BP 13)
KANSL1-AARSchr1744143903chr16702950601933DRB1-0802PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-0802RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-0804PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-0804RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-0804VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-0806PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-0806RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-0806VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-0809PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-0809RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-0813KKKTEFTVKNAQVRG1126
KANSL1-AARSchr1744143903chr16702950601933DRB1-0813PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-0815KKKTEFTVKNAQVRG1126
KANSL1-AARSchr1744143903chr16702950601933DRB1-0820PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-0820RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-0820VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-0820NSIVPLSKKKTEFTV419
KANSL1-AARSchr1744143903chr16702950601933DRB1-0821PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-0821RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-0822PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-0822RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-0822VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-0824PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-0824RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-0828PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-0828RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-0828VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-0828NSIVPLSKKKTEFTV419
KANSL1-AARSchr1744143903chr16702950601933DRB1-0830KKKTEFTVKNAQVRG1126
KANSL1-AARSchr1744143903chr16702950601933DRB1-0831PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-0831RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-0831VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-0831NSIVPLSKKKTEFTV419
KANSL1-AARSchr1744143903chr16702950601933DRB1-1101PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1101RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1101VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1102PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1102RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1102VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1103PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1103RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1103VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1103NSIVPLSKKKTEFTV419
KANSL1-AARSchr1744143903chr16702950601933DRB1-1104PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1104RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1104VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1104NSIVPLSKKKTEFTV419
KANSL1-AARSchr1744143903chr16702950601933DRB1-1105PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1105RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1105VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1106PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1106RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1106VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1106NSIVPLSKKKTEFTV419
KANSL1-AARSchr1744143903chr16702950601933DRB1-1108PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1108RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1109PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1109RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1109VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1110PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1110RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1110VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1111PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1111RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1111VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1112PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1112RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1112VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1113PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1113RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1113VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1114KKKTEFTVKNAQVRG1126
KANSL1-AARSchr1744143903chr16702950601933DRB1-1114PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1114RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1115PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1115RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1115VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1116PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1116RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1116VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1118PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1118RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1118VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1118NSIVPLSKKKTEFTV419
KANSL1-AARSchr1744143903chr16702950601933DRB1-1119PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1119RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1120KKKTEFTVKNAQVRG1126
KANSL1-AARSchr1744143903chr16702950601933DRB1-1120PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1120RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1121PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1121RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1121VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1124PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1124RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1124VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1125PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1125RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1125VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1125NSIVPLSKKKTEFTV419
KANSL1-AARSchr1744143903chr16702950601933DRB1-1127PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1127RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1127VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1128PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1128RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1128VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1129PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1129RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1129VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1131PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1131RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1132PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1132RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1132VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1133PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1133RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1133VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1134PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1134RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1134VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1135PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1135RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1135VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1135NSIVPLSKKKTEFTV419
KANSL1-AARSchr1744143903chr16702950601933DRB1-1136PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1136RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1136VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1137PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1137RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1138PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1138RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1138VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1138NSIVPLSKKKTEFTV419
KANSL1-AARSchr1744143903chr16702950601933DRB1-1139PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1139RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1139VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1141PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1141RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1141VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1141NSIVPLSKKKTEFTV419
KANSL1-AARSchr1744143903chr16702950601933DRB1-1142PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1142RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1142VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1142NSIVPLSKKKTEFTV419
KANSL1-AARSchr1744143903chr16702950601933DRB1-1143PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1143RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1143VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1143NSIVPLSKKKTEFTV419
KANSL1-AARSchr1744143903chr16702950601933DRB1-1144PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1144RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1144VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1144NSIVPLSKKKTEFTV419
KANSL1-AARSchr1744143903chr16702950601933DRB1-1145PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1145KKKTEFTVKNAQVRG1126
KANSL1-AARSchr1744143903chr16702950601933DRB1-1145RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1146PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1146RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1146VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1146NSIVPLSKKKTEFTV419
KANSL1-AARSchr1744143903chr16702950601933DRB1-1147PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1147RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1147VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1147NSIVPLSKKKTEFTV419
KANSL1-AARSchr1744143903chr16702950601933DRB1-1148PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1148RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1148VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1149PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1149RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1149VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1150PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1150RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1150VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1151PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1151RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1151VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1154PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1154RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1154VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1155PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1155RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1155VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1155NSIVPLSKKKTEFTV419
KANSL1-AARSchr1744143903chr16702950601933DRB1-1156PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1156RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1156VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1157PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1157RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1157VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1157NSIVPLSKKKTEFTV419
KANSL1-AARSchr1744143903chr16702950601933DRB1-1158PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1158RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1158VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1158NSIVPLSKKKTEFTV419
KANSL1-AARSchr1744143903chr16702950601933DRB1-1159PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1159RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1159VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1159NSIVPLSKKKTEFTV419
KANSL1-AARSchr1744143903chr16702950601933DRB1-1160PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1160RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1160VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1160NSIVPLSKKKTEFTV419
KANSL1-AARSchr1744143903chr16702950601933DRB1-1161PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1161RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1161VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1162PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1162RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1162VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1163PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1163RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1163VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1163NSIVPLSKKKTEFTV419
KANSL1-AARSchr1744143903chr16702950601933DRB1-1164PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1164RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1164KKKTEFTVKNAQVRG1126
KANSL1-AARSchr1744143903chr16702950601933DRB1-1165PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1165RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1165VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1166PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1166RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1166VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1167PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1167RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1167VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1167NSIVPLSKKKTEFTV419
KANSL1-AARSchr1744143903chr16702950601933DRB1-1168KKKTEFTVKNAQVRG1126
KANSL1-AARSchr1744143903chr16702950601933DRB1-1168PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1168RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1169PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1169RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1169VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1170PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1170RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1170VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1172PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1172RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1172VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1172NSIVPLSKKKTEFTV419
KANSL1-AARSchr1744143903chr16702950601933DRB1-1174PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1174RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1174VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1175PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1175RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1175VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1176PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1176RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1176VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1176NSIVPLSKKKTEFTV419
KANSL1-AARSchr1744143903chr16702950601933DRB1-1177PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1177RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1177VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1177NSIVPLSKKKTEFTV419
KANSL1-AARSchr1744143903chr16702950601933DRB1-1178PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1178RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1178VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1178NSIVPLSKKKTEFTV419
KANSL1-AARSchr1744143903chr16702950601933DRB1-1180PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1180RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1180VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1181PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1181RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1181VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1183PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1183RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1183VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1184PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1184RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1184VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1184NSIVPLSKKKTEFTV419
KANSL1-AARSchr1744143903chr16702950601933DRB1-1185PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1185RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1185VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1185NSIVPLSKKKTEFTV419
KANSL1-AARSchr1744143903chr16702950601933DRB1-1186KKKTEFTVKNAQVRG1126
KANSL1-AARSchr1744143903chr16702950601933DRB1-1187PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1187RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1187VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1188PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1188RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1188VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1189PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1189RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1189VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1190PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1190RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1190VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1191PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1191RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1191VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1192PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1192RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1192VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1192NSIVPLSKKKTEFTV419
KANSL1-AARSchr1744143903chr16702950601933DRB1-1192LVRPNSIVPLSKKKT015
KANSL1-AARSchr1744143903chr16702950601933DRB1-1193PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1193RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1193VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1194PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1194RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1194VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1195PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1195RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1195VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1196PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1196RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1196VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1204PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1204RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1204VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1204NSIVPLSKKKTEFTV419
KANSL1-AARSchr1744143903chr16702950601933DRB1-1209PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1209RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1209VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1209NSIVPLSKKKTEFTV419
KANSL1-AARSchr1744143903chr16702950601933DRB1-1220PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1220RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1220VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1301PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1301RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1301VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1302KKKTEFTVKNAQVRG1126
KANSL1-AARSchr1744143903chr16702950601933DRB1-1302PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1302RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1304PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1304RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1304VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1305PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1305RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1305VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1306PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1306RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1306VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1306NSIVPLSKKKTEFTV419
KANSL1-AARSchr1744143903chr16702950601933DRB1-1307PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1307RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1308PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1308RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1308VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1309PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1309RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1309VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-13100PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-13100RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-13100VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1311PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1311RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1311VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1311NSIVPLSKKKTEFTV419
KANSL1-AARSchr1744143903chr16702950601933DRB1-1314PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1314RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1314VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1315PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1315RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1315VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1316KKKTEFTVKNAQVRG1126
KANSL1-AARSchr1744143903chr16702950601933DRB1-1317PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1317RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1317VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1318PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1318RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1318VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1318NSIVPLSKKKTEFTV419
KANSL1-AARSchr1744143903chr16702950601933DRB1-1319PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1319RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1319VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1320PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1320RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1320VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1322PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1322RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1322VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1323KKKTEFTVKNAQVRG1126
KANSL1-AARSchr1744143903chr16702950601933DRB1-1323PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1323RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1324PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1324RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1324VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1324NSIVPLSKKKTEFTV419
KANSL1-AARSchr1744143903chr16702950601933DRB1-1326PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1326RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1326VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1327PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1327RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1329KKKTEFTVKNAQVRG1126
KANSL1-AARSchr1744143903chr16702950601933DRB1-1329PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1329RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1332PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1332RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1332VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1334KKKTEFTVKNAQVRG1126
KANSL1-AARSchr1744143903chr16702950601933DRB1-1334PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1334RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1335PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1335RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1335VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1336KKKTEFTVKNAQVRG1126
KANSL1-AARSchr1744143903chr16702950601933DRB1-1336PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1336RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1339KKKTEFTVKNAQVRG1126
KANSL1-AARSchr1744143903chr16702950601933DRB1-1339PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1339RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1341KKKTEFTVKNAQVRG1126
KANSL1-AARSchr1744143903chr16702950601933DRB1-1342PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1342RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1342VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1342NSIVPLSKKKTEFTV419
KANSL1-AARSchr1744143903chr16702950601933DRB1-1343PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1343RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1343VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1344PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1344RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1344VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1346PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1346RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1346VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1347PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1347RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1347VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1348PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1348RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1348VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1350PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1350RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1350VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1351PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1351RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1351VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1352PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1352RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1352VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1353PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1353RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1353VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1354PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1354RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1354VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1354NSIVPLSKKKTEFTV419
KANSL1-AARSchr1744143903chr16702950601933DRB1-1356PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1356RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1357PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1357RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1357VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1358PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1358RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1359PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1359RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1359VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1360PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1360RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1361PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1361RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1362PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1362RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1362VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1363PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1363RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1363VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1364PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1364RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1364VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1367KKKTEFTVKNAQVRG1126
KANSL1-AARSchr1744143903chr16702950601933DRB1-1368PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1368RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1368VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1369PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1369RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1369VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1370PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1370RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1370VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1371PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1371RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1371VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1372PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1372RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1372VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1373KKKTEFTVKNAQVRG1126
KANSL1-AARSchr1744143903chr16702950601933DRB1-1373PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1373RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1374KKKTEFTVKNAQVRG1126
KANSL1-AARSchr1744143903chr16702950601933DRB1-1374PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1374RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1375PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1375RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1375VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1376PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1376RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1377PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1377RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1377VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1378PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1378RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1378VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1379PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1379RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1379VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1380PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1380RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1380VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1382PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1382RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1383PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1383RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1383VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1384PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1384RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1384VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1386PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1386RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1387PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1387RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1387VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1391PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1391RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1391VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1392PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1392RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1392VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1393PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1393RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1393VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1396KKKTEFTVKNAQVRG1126
KANSL1-AARSchr1744143903chr16702950601933DRB1-1397KKKTEFTVKNAQVRG1126
KANSL1-AARSchr1744143903chr16702950601933DRB1-1397PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1397RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1398PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1398RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1398VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1399KKKTEFTVKNAQVRG1126
KANSL1-AARSchr1744143903chr16702950601933DRB1-1399PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1399RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1403KKKTEFTVKNAQVRG1126
KANSL1-AARSchr1744143903chr16702950601933DRB1-1403PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1403RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1406PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1406RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1406VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1411PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1411RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1412PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1412RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1412VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1412NSIVPLSKKKTEFTV419
KANSL1-AARSchr1744143903chr16702950601933DRB1-1415PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1415RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1415VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1416PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1416RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1416VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1417PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1417RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1417VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1418PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1418RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1420PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1420RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1420VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1421PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1421RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1422PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1422RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1424KKKTEFTVKNAQVRG1126
KANSL1-AARSchr1744143903chr16702950601933DRB1-1425PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1425RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1427PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1427RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1427VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1429PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1429RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1429VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1431PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1431RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1432PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1432RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1433PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1434PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1434RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1434VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1437PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1437RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1437VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1440KKKTEFTVKNAQVRG1126
KANSL1-AARSchr1744143903chr16702950601933DRB1-1440PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1440RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1447KKKTEFTVKNAQVRG1126
KANSL1-AARSchr1744143903chr16702950601933DRB1-1452PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1452RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1452VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1453PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1453RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1453VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1455PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1464PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1465PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1465RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1467KKKTEFTVKNAQVRG1126
KANSL1-AARSchr1744143903chr16702950601933DRB1-1467PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1467RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1472PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1473PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1473RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1473VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1474PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1474RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1474VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1477KKKTEFTVKNAQVRG1126
KANSL1-AARSchr1744143903chr16702950601933DRB1-1477PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1477RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1478PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1478RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1478VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1480PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1480RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1480VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1481PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1481RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1481VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1483PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1483RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1483VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1484PNSIVPLSKKKTEFT318
KANSL1-AARSchr1744143903chr16702950601933DRB1-1484RPNSIVPLSKKKTEF217
KANSL1-AARSchr1744143903chr16702950601933DRB1-1484VRPNSIVPLSKKKTE116
KANSL1-AARSchr1744143903chr16702950601933DRB1-1489KKKTEFTVKNAQVRG1126
KANSL1-AARSchr1744143903chr16702950601933DRB1-1498KKKTEFTVKNAQVRG1126
KANSL1-AARSchr1744143903chr16702950601933DRB5-0101KKKTEFTVKNAQVRG1126
KANSL1-AARSchr1744143903chr16702950601933DRB5-0102KKKTEFTVKNAQVRG1126
KANSL1-AARSchr1744143903chr16702950601933DRB5-0103KKKTEFTVKNAQVRG1126
KANSL1-AARSchr1744143903chr16702950601933DRB5-0104KKKTEFTVKNAQVRG1126
KANSL1-AARSchr1744143903chr16702950601933DRB5-0105KKKTEFTVKNAQVRG1126
KANSL1-AARSchr1744143903chr16702950601933DRB5-0108NKKKTEFTVKNAQVRG1126
KANSL1-AARSchr1744143903chr16702950601933DRB5-0111KKKTEFTVKNAQVRG1126
KANSL1-AARSchr1744143903chr16702950601933DRB5-0113KKKTEFTVKNAQVRG1126
KANSL1-AARSchr1744143903chr16702950601933DRB5-0114KKKTEFTVKNAQVRG1126
KANSL1-AARSchr1744143903chr16702950601933DRB5-0203KKKTEFTVKNAQVRG1126

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Fusion breakpoint peptide structures of KANSL1-AARS

check button3D structures of the fusion breakpoint peptide of 14AA sequence that have potential fusion neoantigens
* The minimum length of the amino acid sequence in RoseTTAFold is 14AA. Here, we predicted the 14AA fusion protein breakpoint sequence not the fusion neoantigen peptide, which is shorter than 14 AA.
File nameBPseqHgeneTgeneHchrHbpTchrTbpAAlen
4057IVPLSKKKTEFTVKKANSL1AARSchr1744143903chr16702950601933

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Filtering FusionNeoAntigens Through Checking the Interaction with HLAs in 3D of KANSL1-AARS

check buttonVirtual screening between 25 HLAs (from PDB) and FusionNeoAntigens
* We used Glide to predict the interaction between HLAs and neoantigens.
HLA allelePDB IDFile nameBPseqDocking scoreGlide score
HLA-B14:023BVN4057IVPLSKKKTEFTVK-7.9962-8.1096
HLA-B14:023BVN4057IVPLSKKKTEFTVK-5.70842-6.74372
HLA-B52:013W394057IVPLSKKKTEFTVK-6.83737-6.95077
HLA-B52:013W394057IVPLSKKKTEFTVK-4.4836-5.5189
HLA-A11:014UQ24057IVPLSKKKTEFTVK-10.0067-10.1201
HLA-A11:014UQ24057IVPLSKKKTEFTVK-9.03915-10.0745
HLA-A24:025HGA4057IVPLSKKKTEFTVK-6.56204-6.67544
HLA-A24:025HGA4057IVPLSKKKTEFTVK-5.42271-6.45801
HLA-B44:053DX84057IVPLSKKKTEFTVK-7.85648-8.89178
HLA-B44:053DX84057IVPLSKKKTEFTVK-5.3978-5.5112
HLA-A02:016TDR4057IVPLSKKKTEFTVK-3.37154-4.40684

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Vaccine Design for the FusionNeoAntigens of KANSL1-AARS

check button mRNA and peptide sequences of FusionNeoAntigens that have potential interaction with HLA-Is.
Fusion geneHchrHbpTchrTbpStart in +/-13AAEnd in +/-13AAFusionNeoAntigen peptide sequenceFusionNeoAntigen RNA sequence
KANSL1-AARSchr1744143903chr1670295060514SIVPLSKKKAGCATCGTTCCTCTTTCCAAGAAGAAA
KANSL1-AARSchr1744143903chr1670295060717VPLSKKKTEFGTTCCTCTTTCCAAGAAGAAAACAGAGTTT
KANSL1-AARSchr1744143903chr1670295060917LSKKKTEFCTTTCCAAGAAGAAAACAGAGTTT

check button mRNA and peptide sequences of FusionNeoAntigens that have potential interaction with HLA-IIs.
Fusion geneHchrHbpTchrTbpStart in +/-13AAEnd in +/-13AAFusionNeoAntigen peptideFusionNEoAntigen RNA sequence
KANSL1-AARSchr1744143903chr1670295060015LVRPNSIVPLSKKKTCTTGTTCGACCCAACAGCATCGTTCCTCTTTCCAAGAAGAAAACA
KANSL1-AARSchr1744143903chr1670295060116VRPNSIVPLSKKKTEGTTCGACCCAACAGCATCGTTCCTCTTTCCAAGAAGAAAACAGAG
KANSL1-AARSchr1744143903chr16702950601126KKKTEFTVKNAQVRGAAGAAGAAAACAGAGTTTACAGTGAAGAATGCTCAGGTCCGAGGA
KANSL1-AARSchr1744143903chr1670295060217RPNSIVPLSKKKTEFCGACCCAACAGCATCGTTCCTCTTTCCAAGAAGAAAACAGAGTTT
KANSL1-AARSchr1744143903chr1670295060318PNSIVPLSKKKTEFTCCCAACAGCATCGTTCCTCTTTCCAAGAAGAAAACAGAGTTTACA
KANSL1-AARSchr1744143903chr1670295060419NSIVPLSKKKTEFTVAACAGCATCGTTCCTCTTTCCAAGAAGAAAACAGAGTTTACAGTG

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Information of the samples that have these potential fusion neoantigens of KANSL1-AARS

check button These samples were reported as having these fusion breakpoints. For individual breakpoints, we checked the open reading frames considering multiple gene isoforms and chose the in-frame fusion genes only. Then, we made fusion protein sequences and predicted the fusion neoantigens. These fusion-positive samples may have these potential fusion neoantigens.
Cancer typeFusion geneHchrHbpHenstTchrTbpTenstSample
SKCMKANSL1-AARSchr1744143903ENST00000432791chr1670295060ENST00000261772TCGA-FR-A8YC-06A

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Potential target of CAR-T therapy development for KANSL1-AARS

check button Predicted 3D structure. We used RoseTTAFold.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, to provide the retention of the transmembrane domain, we only show the protein feature retention information of those transmembrane features


* Minus value of BPloci means that the break point is located before the CDS.
- In-frame and retained 'Transmembrane'.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

check button Subcellular localization prediction of the transmembrane domain retained fusion proteins
* We used DeepLoc 1.0. The order of the X-axis of the barplot is as follows: Entry_ID, Localization, Type, Nucleus, Cytoplasm, Extracellular, Mitochondrion, Cell_membrane, Endoplasmic_reticulum, Plastid, Golgi.apparatus, Lysosome.Vacuole, Peroxisome. Y-axis is the output score of DeepLoc. Clicking the image will open a new tab with a large image.
HgeneHchrHbpHenstTgeneTchrTbpTenstDeepLoc result

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Related Drugs to KANSL1-AARS

check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

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Related Diseases to KANSL1-AARS

check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource