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Fusion Protein:LTK-ITGB4 |
Fusion Gene and Fusion Protein Summary |
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Fusion partner gene information | Fusion gene name: LTK-ITGB4 | FusionPDB ID: 50316 | FusionGDB2.0 ID: 50316 | Hgene | Tgene | Gene symbol | LTK | ITGB4 | Gene ID | 4058 | 3691 |
Gene name | leukocyte receptor tyrosine kinase | integrin subunit beta 4 | |
Synonyms | TYK1 | CD104|GP150 | |
Cytomap | 15q15.1 | 17q25.1 | |
Type of gene | protein-coding | protein-coding | |
Description | leukocyte tyrosine kinase receptorprotein tyrosine kinase 1 | integrin beta-4CD104 antigen | |
Modification date | 20200320 | 20200329 | |
UniProtAcc | P29376 Main function of 5'-partner protein: FUNCTION: Receptor with a tyrosine-protein kinase activity. The exact function of this protein is not known. Studies with chimeric proteins (replacing its extracellular region with that of several known growth factor receptors, such as EGFR and CSFIR) demonstrate its ability to promote growth and specifically neurite outgrowth, and cell survival. Signaling appears to involve the PI3 kinase pathway. Involved in regulation of the secretory pathway involving endoplasmic reticulum (ER) export sites (ERESs) and ER to Golgi transport. {ECO:0000269|PubMed:20548102}. | P16144 Main function of 5'-partner protein: FUNCTION: Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed:20682778). ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed:22351760). ITGA6:ITGB4 binds to IGF2 and this binding is essential for IGF2 signaling (PubMed:28873464). {ECO:0000269|PubMed:12482924, ECO:0000269|PubMed:19403692, ECO:0000269|PubMed:20682778, ECO:0000269|PubMed:22351760, ECO:0000269|PubMed:28873464}. | |
Ensembl transtripts involved in fusion gene | ENST ids | ENST00000263800, ENST00000355166, ENST00000453182, ENST00000561619, | ENST00000584558, ENST00000200181, ENST00000339591, ENST00000449880, ENST00000450894, ENST00000579662, |
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0) | * DoF score | 1 X 1 X 1=1 | 8 X 8 X 7=448 |
# samples | 1 | 9 | |
** MAII score | log2(1/1*10)=3.32192809488736 | log2(9/448*10)=-2.31550182572793 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
Fusion gene context | PubMed: LTK [Title/Abstract] AND ITGB4 [Title/Abstract] AND fusion [Title/Abstract] | ||
Fusion neoantigen context | PubMed: LTK [Title/Abstract] AND ITGB4 [Title/Abstract] AND neoantigen [Title/Abstract] | ||
Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0) | LTK(41799292)-ITGB4(73746760), # samples:1 | ||
Anticipated loss of major functional domain due to fusion event. | LTK-ITGB4 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. LTK-ITGB4 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. LTK-ITGB4 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. LTK-ITGB4 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. LTK-ITGB4 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF. LTK-ITGB4 seems lost the major protein functional domain in Hgene partner, which is a kinase due to the frame-shifted ORF. LTK-ITGB4 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF. LTK-ITGB4 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF. |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
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Partner | Gene | GO ID | GO term | PubMed ID |
Hgene | LTK | GO:0006468 | protein phosphorylation | 9223670 |
Hgene | LTK | GO:0008283 | cell proliferation | 10445845 |
Hgene | LTK | GO:0010666 | positive regulation of cardiac muscle cell apoptotic process | 10445845 |
Tgene | ITGB4 | GO:0009611 | response to wounding | 19403692 |
Tgene | ITGB4 | GO:0031581 | hemidesmosome assembly | 12482924 |
![]() Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr15:41799292/chr17:73746760) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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![]() * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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![]() * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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Fusion Amino Acid Sequences |
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Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
ENST00000453182 | LTK | chr15 | 41799292 | - | ENST00000579662 | ITGB4 | chr17 | 73746760 | + | 3254 | 1420 | 178 | 3204 | 1008 |
ENST00000453182 | LTK | chr15 | 41799292 | - | ENST00000339591 | ITGB4 | chr17 | 73746760 | + | 3626 | 1420 | 178 | 3363 | 1061 |
ENST00000453182 | LTK | chr15 | 41799292 | - | ENST00000200181 | ITGB4 | chr17 | 73746760 | + | 3678 | 1420 | 178 | 3414 | 1078 |
ENST00000453182 | LTK | chr15 | 41799292 | - | ENST00000450894 | ITGB4 | chr17 | 73746760 | + | 3465 | 1420 | 178 | 3204 | 1008 |
ENST00000453182 | LTK | chr15 | 41799292 | - | ENST00000449880 | ITGB4 | chr17 | 73746760 | + | 3627 | 1420 | 178 | 3363 | 1061 |
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Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
ENST00000453182 | ENST00000579662 | LTK | chr15 | 41799292 | - | ITGB4 | chr17 | 73746760 | + | 0.004724446 | 0.9952755 |
ENST00000453182 | ENST00000339591 | LTK | chr15 | 41799292 | - | ITGB4 | chr17 | 73746760 | + | 0.007585716 | 0.9924143 |
ENST00000453182 | ENST00000200181 | LTK | chr15 | 41799292 | - | ITGB4 | chr17 | 73746760 | + | 0.004920512 | 0.9950795 |
ENST00000453182 | ENST00000450894 | LTK | chr15 | 41799292 | - | ITGB4 | chr17 | 73746760 | + | 0.004421385 | 0.9955786 |
ENST00000453182 | ENST00000449880 | LTK | chr15 | 41799292 | - | ITGB4 | chr17 | 73746760 | + | 0.007598937 | 0.992401 |
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Get the fusion protein sequences from here. |
Fusion protein sequence information is available in the fasta format. >FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP |
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Fusion Protein Breakpoint Sequences for LTK-ITGB4 |
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Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | Length(fusion protein) | BP in fusion protein | Peptide |
LTK | chr15 | 41799292 | ITGB4 | chr17 | 73746760 | 1420 | 414 | CHRGFPSQCYSAQVKYWIQGDSESEA |
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Potential FusionNeoAntigen Information of LTK-ITGB4 in HLA I |
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LTK-ITGB4_41799292_73746760.msa |
![]() * We used NetMHCpan v4.1 (%rank<0.5) and deepHLApan v1.1 (immunogenic score>0.5) |
Fusion gene | Hchr | Hbp | Tgene | Tchr | Tbp | HLA I | FusionNeoAntigen peptide | Binding score | Immunogenic score | Neoantigen start (at BP 13) | Neoantigen end (at BP 13) |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 1420 | HLA-B57:01 | YSAQVKYW | 0.9999 | 0.85 | 9 | 17 |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 1420 | HLA-B58:02 | YSAQVKYW | 0.9994 | 0.7116 | 9 | 17 |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 1420 | HLA-B58:01 | YSAQVKYW | 0.9993 | 0.7079 | 9 | 17 |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 1420 | HLA-B57:03 | YSAQVKYW | 0.9989 | 0.8764 | 9 | 17 |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 1420 | HLA-B15:25 | QCYSAQVKY | 0.9435 | 0.6189 | 7 | 16 |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 1420 | HLA-B15:02 | QCYSAQVKY | 0.9222 | 0.6434 | 7 | 16 |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 1420 | HLA-B57:01 | QCYSAQVKYW | 0.9998 | 0.8471 | 7 | 17 |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 1420 | HLA-B58:02 | QCYSAQVKYW | 0.9991 | 0.741 | 7 | 17 |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 1420 | HLA-B58:01 | QCYSAQVKYW | 0.9973 | 0.7728 | 7 | 17 |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 1420 | HLA-B57:03 | QCYSAQVKYW | 0.9902 | 0.856 | 7 | 17 |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 1420 | HLA-B15:02 | SQCYSAQVKY | 0.9466 | 0.5229 | 6 | 16 |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 1420 | HLA-B15:21 | QCYSAQVKY | 0.9303 | 0.6279 | 7 | 16 |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 1420 | HLA-B15:05 | QCYSAQVKY | 0.8483 | 0.6037 | 7 | 16 |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 1420 | HLA-B15:31 | QCYSAQVKY | 0.785 | 0.6154 | 7 | 16 |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 1420 | HLA-C15:04 | QCYSAQVKY | 0.4481 | 0.7123 | 7 | 16 |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 1420 | HLA-B54:01 | FPSQCYSAQV | 0.9963 | 0.5564 | 4 | 14 |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 1420 | HLA-B15:04 | SQCYSAQVKY | 0.9558 | 0.5276 | 6 | 16 |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 1420 | HLA-B57:10 | YSAQVKYW | 0.9999 | 0.85 | 9 | 17 |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 1420 | HLA-B57:04 | YSAQVKYW | 0.9997 | 0.5946 | 9 | 17 |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 1420 | HLA-B58:06 | YSAQVKYW | 0.9991 | 0.6235 | 9 | 17 |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 1420 | HLA-B57:02 | YSAQVKYW | 0.9987 | 0.7104 | 9 | 17 |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 1420 | HLA-B35:11 | QCYSAQVKY | 0.9214 | 0.6298 | 7 | 16 |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 1420 | HLA-B15:20 | QCYSAQVKY | 0.8579 | 0.6923 | 7 | 16 |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 1420 | HLA-B35:28 | QCYSAQVKY | 0.8264 | 0.703 | 7 | 16 |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 1420 | HLA-B35:23 | QCYSAQVKY | 0.8042 | 0.6808 | 7 | 16 |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 1420 | HLA-B35:20 | QCYSAQVKY | 0.7943 | 0.7293 | 7 | 16 |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 1420 | HLA-C15:09 | QCYSAQVKY | 0.4481 | 0.7123 | 7 | 16 |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 1420 | HLA-B18:04 | QCYSAQVKY | 0.2197 | 0.7467 | 7 | 16 |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 1420 | HLA-B57:10 | QCYSAQVKYW | 0.9998 | 0.8471 | 7 | 17 |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 1420 | HLA-B15:135 | SQCYSAQVKY | 0.9996 | 0.5654 | 6 | 16 |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 1420 | HLA-B15:50 | SQCYSAQVKY | 0.9995 | 0.5094 | 6 | 16 |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 1420 | HLA-B15:24 | SQCYSAQVKY | 0.999 | 0.5047 | 6 | 16 |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 1420 | HLA-B57:04 | QCYSAQVKYW | 0.9984 | 0.6181 | 7 | 17 |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 1420 | HLA-B15:20 | SQCYSAQVKY | 0.9245 | 0.54 | 6 | 16 |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 1420 | HLA-B35:28 | SQCYSAQVKY | 0.8958 | 0.5613 | 6 | 16 |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 1420 | HLA-B35:20 | SQCYSAQVKY | 0.7969 | 0.5775 | 6 | 16 |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 1420 | HLA-B48:02 | SQCYSAQVKY | 0.6969 | 0.5316 | 6 | 16 |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 1420 | HLA-B18:04 | SQCYSAQVKY | 0.4668 | 0.5738 | 6 | 16 |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 1420 | HLA-B15:24 | SQCYSAQVKYW | 0.9989 | 0.7646 | 6 | 17 |
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Potential FusionNeoAntigen Information of LTK-ITGB4 in HLA II |
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LTK-ITGB4_41799292_73746760.msa |
![]() * We used NetMHCIIpan v4.1 (%rank<0.5). |
Fusion gene | Hchr | Hbp | Tgene | Tchr | Tbp | HLA II | FusionNeoAntigen peptide | Neoantigen start (at BP 13) | Neoantigen end (at BP 13) |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 1420 | DRB1-0401 | AQVKYWIQGDSESEA | 11 | 26 |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 1420 | DRB1-0419 | AQVKYWIQGDSESEA | 11 | 26 |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 1420 | DRB1-0433 | AQVKYWIQGDSESEA | 11 | 26 |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 1420 | DRB1-0435 | AQVKYWIQGDSESEA | 11 | 26 |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 1420 | DRB1-0438 | AQVKYWIQGDSESEA | 11 | 26 |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 1420 | DRB1-0461 | AQVKYWIQGDSESEA | 11 | 26 |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 1420 | DRB1-0463 | AQVKYWIQGDSESEA | 11 | 26 |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 1420 | DRB1-0464 | AQVKYWIQGDSESEA | 11 | 26 |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 1420 | DRB1-0472 | AQVKYWIQGDSESEA | 11 | 26 |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 1420 | DRB1-0475 | AQVKYWIQGDSESEA | 11 | 26 |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 1420 | DRB1-0476 | AQVKYWIQGDSESEA | 11 | 26 |
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Fusion breakpoint peptide structures of LTK-ITGB4 |
![]() * The minimum length of the amino acid sequence in RoseTTAFold is 14AA. Here, we predicted the 14AA fusion protein breakpoint sequence not the fusion neoantigen peptide, which is shorter than 14 AA. |
File name | BPseq | Hgene | Tgene | Hchr | Hbp | Tchr | Tbp | AAlen |
8912 | SQCYSAQVKYWIQG | LTK | ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 1420 |
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Filtering FusionNeoAntigens Through Checking the Interaction with HLAs in 3D of LTK-ITGB4 |
![]() * We used Glide to predict the interaction between HLAs and neoantigens. |
HLA allele | PDB ID | File name | BPseq | Docking score | Glide score |
HLA-B14:02 | 3BVN | 8912 | SQCYSAQVKYWIQG | -7.9962 | -8.1096 |
HLA-B14:02 | 3BVN | 8912 | SQCYSAQVKYWIQG | -5.70842 | -6.74372 |
HLA-B52:01 | 3W39 | 8912 | SQCYSAQVKYWIQG | -6.83737 | -6.95077 |
HLA-B52:01 | 3W39 | 8912 | SQCYSAQVKYWIQG | -4.4836 | -5.5189 |
HLA-A11:01 | 4UQ2 | 8912 | SQCYSAQVKYWIQG | -10.0067 | -10.1201 |
HLA-A11:01 | 4UQ2 | 8912 | SQCYSAQVKYWIQG | -9.03915 | -10.0745 |
HLA-A24:02 | 5HGA | 8912 | SQCYSAQVKYWIQG | -6.56204 | -6.67544 |
HLA-A24:02 | 5HGA | 8912 | SQCYSAQVKYWIQG | -5.42271 | -6.45801 |
HLA-B44:05 | 3DX8 | 8912 | SQCYSAQVKYWIQG | -7.85648 | -8.89178 |
HLA-B44:05 | 3DX8 | 8912 | SQCYSAQVKYWIQG | -5.3978 | -5.5112 |
HLA-A02:01 | 6TDR | 8912 | SQCYSAQVKYWIQG | -3.37154 | -4.40684 |
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Vaccine Design for the FusionNeoAntigens of LTK-ITGB4 |
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Fusion gene | Hchr | Hbp | Tchr | Tbp | Start in +/-13AA | End in +/-13AA | FusionNeoAntigen peptide sequence | FusionNeoAntigen RNA sequence |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 4 | 14 | FPSQCYSAQV | TTCCCCAGCCAATGTTACTCTGCTCAGGTA |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 6 | 16 | SQCYSAQVKY | AGCCAATGTTACTCTGCTCAGGTAAAGTAC |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 6 | 17 | SQCYSAQVKYW | AGCCAATGTTACTCTGCTCAGGTAAAGTACTGG |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 7 | 16 | QCYSAQVKY | CAATGTTACTCTGCTCAGGTAAAGTAC |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 7 | 17 | QCYSAQVKYW | CAATGTTACTCTGCTCAGGTAAAGTACTGG |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 9 | 17 | YSAQVKYW | TACTCTGCTCAGGTAAAGTACTGG |
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Fusion gene | Hchr | Hbp | Tchr | Tbp | Start in +/-13AA | End in +/-13AA | FusionNeoAntigen peptide | FusionNEoAntigen RNA sequence |
LTK-ITGB4 | chr15 | 41799292 | chr17 | 73746760 | 11 | 26 | AQVKYWIQGDSESEA | GCTCAGGTAAAGTACTGGATTCAGGGTGACTCCGAATCCGAAGCC |
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Information of the samples that have these potential fusion neoantigens of LTK-ITGB4 |
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Cancer type | Fusion gene | Hchr | Hbp | Henst | Tchr | Tbp | Tenst | Sample |
Non-Cancer | LTK-ITGB4 | chr15 | 41799292 | ENST00000453182 | chr17 | 73746760 | ENST00000200181 | 161N |
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Potential target of CAR-T therapy development for LTK-ITGB4 |
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![]() * Minus value of BPloci means that the break point is located before the CDS. |
- In-frame and retained 'Transmembrane'. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
Hgene | LTK | chr15:41799292 | chr17:73746760 | ENST00000263800 | - | 11 | 20 | 425_449 | 513 | 865.0 | Transmembrane | Helical |
Hgene | LTK | chr15:41799292 | chr17:73746760 | ENST00000355166 | - | 10 | 19 | 425_449 | 452 | 804.0 | Transmembrane | Helical |
![]() * We used DeepLoc 1.0. The order of the X-axis of the barplot is as follows: Entry_ID, Localization, Type, Nucleus, Cytoplasm, Extracellular, Mitochondrion, Cell_membrane, Endoplasmic_reticulum, Plastid, Golgi.apparatus, Lysosome.Vacuole, Peroxisome. Y-axis is the output score of DeepLoc. Clicking the image will open a new tab with a large image. |
Hgene | Hchr | Hbp | Henst | Tgene | Tchr | Tbp | Tenst | DeepLoc result |
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Related Drugs to LTK-ITGB4 |
![]() (Manual curation of PubMed, 04-30-2022 + MyCancerGenome) |
Hgene | Tgene | Drug | Source | PMID |
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Related Diseases to LTK-ITGB4 |
![]() (Manual curation of PubMed, 04-30-2022 + MyCancerGenome) |
Hgene | Tgene | Disease | Source | PMID |
![]() (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |