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Fusion Protein:TLK2-SLC38A10

Fusion Gene and Fusion Protein Summary

Fusion gene summary

Fusion partner gene information	Fusion gene name: TLK2-SLC38A10
	FusionPDB ID: 91167
	FusionGDB2.0 ID: 91167
		Hgene	Tgene
	Gene symbol	TLK2	SLC38A10
	Gene ID	11011	124565
	Gene name	tousled like kinase 2	solute carrier family 38 member 10
	Synonyms	HsHPK\|MRD57\|PKU-ALPHA	PP1744
	Cytomap	17q23.2	17q25.3
	Type of gene	protein-coding	protein-coding
	Description	serine/threonine-protein kinase tousled-like 2	putative sodium-coupled neutral amino acid transporter 10
	Modification date	20200313	20200313
	UniProtAcc	.	.
Ensembl transtripts involved in fusion gene	ENST ids	ENST00000326270, ENST00000343388, ENST00000346027, ENST00000542523, ENST00000582809, ENST00000577616,	ENST00000546352, ENST00000288439, ENST00000374759,
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)	* DoF score	18 X 11 X 9=1782	7 X 5 X 6=210
	# samples	24	8
	** MAII score	log2(24/1782*10)=-2.8923910259134 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(8/210*10)=-1.39231742277876 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Fusion gene context	PubMed: TLK2 [Title/Abstract] AND SLC38A10 [Title/Abstract] AND fusion [Title/Abstract]
Fusion neoantigen context	PubMed: TLK2 [Title/Abstract] AND SLC38A10 [Title/Abstract] AND neoantigen [Title/Abstract]
Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)	TLK2(60629758)-SLC38A10(79256132), # samples:1
Anticipated loss of major functional domain due to fusion event.	TLK2-SLC38A10 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. TLK2-SLC38A10 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	TLK2	GO:0001672	regulation of chromatin assembly or disassembly	12660173
Hgene	TLK2	GO:0006468	protein phosphorylation	12660173
Hgene	TLK2	GO:0006974	cellular response to DNA damage stimulus	12660173
Hgene	TLK2	GO:0018105	peptidyl-serine phosphorylation	20016786
Hgene	TLK2	GO:0035556	intracellular signal transduction	12660173
Hgene	TLK2	GO:0071480	cellular response to gamma radiation	12660173

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:60629758/chr17:79256132)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Retention analysis results of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features, are available here.

Fusion gene breakpoints across TLK2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across SLC38A10 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

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Fusion Amino Acid Sequences

Fusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000582809	TLK2	chr17	60629758	+	ENST00000374759	SLC38A10	chr17	79256132	-	4442	883	370	3885	1171
ENST00000582809	TLK2	chr17	60629758	+	ENST00000288439	SLC38A10	chr17	79256132	-	2888	883	370	2868	832
ENST00000326270	TLK2	chr17	60629758	+	ENST00000374759	SLC38A10	chr17	79256132	-	4454	895	121	3897	1258
ENST00000326270	TLK2	chr17	60629758	+	ENST00000288439	SLC38A10	chr17	79256132	-	2900	895	121	2880	919
ENST00000346027	TLK2	chr17	60629758	+	ENST00000374759	SLC38A10	chr17	79256132	-	4457	898	121	3900	1259
ENST00000346027	TLK2	chr17	60629758	+	ENST00000288439	SLC38A10	chr17	79256132	-	2903	898	121	2883	920
ENST00000343388	TLK2	chr17	60629758	+	ENST00000374759	SLC38A10	chr17	79256132	-	4236	677	50	3679	1209
ENST00000343388	TLK2	chr17	60629758	+	ENST00000288439	SLC38A10	chr17	79256132	-	2682	677	50	2662	870
ENST00000542523	TLK2	chr17	60629758	+	ENST00000374759	SLC38A10	chr17	79256132	-	4115	556	25	3558	1177
ENST00000542523	TLK2	chr17	60629758	+	ENST00000288439	SLC38A10	chr17	79256132	-	2561	556	25	2541	838

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000582809	ENST00000374759	TLK2	chr17	60629758	+	SLC38A10	chr17	79256132	-	0.010669944	0.9893301
ENST00000582809	ENST00000288439	TLK2	chr17	60629758	+	SLC38A10	chr17	79256132	-	0.01924864	0.9807514
ENST00000326270	ENST00000374759	TLK2	chr17	60629758	+	SLC38A10	chr17	79256132	-	0.0073654	0.9926346
ENST00000326270	ENST00000288439	TLK2	chr17	60629758	+	SLC38A10	chr17	79256132	-	0.003010577	0.9969894
ENST00000346027	ENST00000374759	TLK2	chr17	60629758	+	SLC38A10	chr17	79256132	-	0.007570317	0.9924297
ENST00000346027	ENST00000288439	TLK2	chr17	60629758	+	SLC38A10	chr17	79256132	-	0.003158055	0.9968419
ENST00000343388	ENST00000374759	TLK2	chr17	60629758	+	SLC38A10	chr17	79256132	-	0.006910962	0.993089
ENST00000343388	ENST00000288439	TLK2	chr17	60629758	+	SLC38A10	chr17	79256132	-	0.005031834	0.9949681
ENST00000542523	ENST00000374759	TLK2	chr17	60629758	+	SLC38A10	chr17	79256132	-	0.006417395	0.99358255
ENST00000542523	ENST00000288439	TLK2	chr17	60629758	+	SLC38A10	chr17	79256132	-	0.004998276	0.99500173

Predicted full-length fusion amino acid sequences. For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among all the predicted ones.

Get the fusion protein sequences from here.

Fusion protein sequence information is available in the fasta format.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

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Fusion Protein Breakpoint Sequences for TLK2-SLC38A10

+/-13 AA sequence from the breakpoints of the fusion protein sequences.

Hgene	Hchr	Hbp	Tgene	Tchr	Tbp	Length(fusion protein)	BP in fusion protein	Peptide
TLK2	chr17	60629758	SLC38A10	chr17	79256132	556	176	SSQKQISIQHRQTQVGGTFRMFLLFA
TLK2	chr17	60629758	SLC38A10	chr17	79256132	677	208	SSQKQISIQHRQTQVGGTFRMFLLFA
TLK2	chr17	60629758	SLC38A10	chr17	79256132	883	170	SSQKQISIQHRQTQVGGTFRMFLLFA
TLK2	chr17	60629758	SLC38A10	chr17	79256132	895	257	SSQKQISIQHRQTQVGGTFRMFLLFA
TLK2	chr17	60629758	SLC38A10	chr17	79256132	898	258	SSQKQISIQHRQTQVGGTFRMFLLFA

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Potential FusionNeoAntigen Information of TLK2-SLC38A10 in HLA I

Multiple sequence alignments of the potential FusionNeoAntigens per fusion breakpoints. If the MSA is empty, then it means that there were predicted fusion neoantigens in this fusion breakpoint, but those predicted fusion neoantigens were not across the breakpoint, which is not fusion-specific.

TLK2-SLC38A10_60629758_79256132.msa

Potential FusionNeoAntigen Information
* We used NetMHCpan v4.1 (%rank<0.5) and deepHLApan v1.1 (immunogenic score>0.5)

Fusion gene	Hchr	Hbp	Tgene	Tchr	Tbp	HLA I	FusionNeoAntigen peptide	Binding score	Immunogenic score	Neoantigen start (at BP 13)	Neoantigen end (at BP 13)
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B52:01	IQHRQTQV	0.8239	0.9384	7	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:01	RQTQVGGTF	0.9969	0.905	10	19
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B48:01	TQVGGTFRM	0.9766	0.623	12	21
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-A02:38	SIQHRQTQV	0.8938	0.5266	6	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B13:02	TQVGGTFRM	0.8807	0.73	12	21
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B13:01	TQVGGTFRM	0.8494	0.9819	12	21
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:03	TQVGGTFRM	0.8469	0.8494	12	21
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B39:01	TQVGGTFRM	0.8468	0.8328	12	21
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:18	TQVGGTFRM	0.8242	0.7946	12	21
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B48:01	RQTQVGGTF	0.7948	0.56	10	19
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B39:13	TQVGGTFRM	0.7557	0.8829	12	21
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B38:02	TQVGGTFRM	0.7521	0.9247	12	21
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:25	RQTQVGGTF	0.7263	0.941	10	19
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:10	TQVGGTFRM	0.6451	0.5637	12	21
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:03	RQTQVGGTF	0.6264	0.8385	10	19
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:37	TQVGGTFRM	0.4615	0.6231	12	21
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:18	RQTQVGGTF	0.4181	0.7624	10	19
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B13:01	RQTQVGGTF	0.3589	0.9687	10	19
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B39:13	RQTQVGGTF	0.2032	0.9199	10	19
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:01	TQVGGTFRMF	0.9999	0.8661	12	22
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B27:04	HRQTQVGGTF	0.9993	0.6143	9	19
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:03	TQVGGTFRMF	0.9831	0.822	12	22
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:18	HRQTQVGGTF	0.9489	0.6393	9	19
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B13:01	TQVGGTFRMF	0.9336	0.9797	12	22
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:01	HRQTQVGGTF	0.8433	0.8521	9	19
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:18	QHRQTQVGGTF	0.99	0.7066	8	19
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B38:01	QHRQTQVGGTF	0.9793	0.9545	8	19
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B38:02	QHRQTQVGGTF	0.9728	0.9486	8	19
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:04	TQVGGTFRM	0.9407	0.9408	12	21
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:07	RQTQVGGTF	0.925	0.6113	10	19
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:21	TQVGGTFRM	0.9171	0.9218	12	21
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:04	RQTQVGGTF	0.9037	0.9201	10	19
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B39:09	TQVGGTFRM	0.8531	0.6478	12	21
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B48:03	TQVGGTFRM	0.7935	0.5274	12	21
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:05	TQVGGTFRM	0.7521	0.8794	12	21
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B39:05	TQVGGTFRM	0.7327	0.8206	12	21
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:05	RQTQVGGTF	0.2716	0.9159	10	19
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B39:08	RQTQVGGTF	0.2436	0.8896	10	19
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:05	TQVGGTFRMF	0.9288	0.8813	12	22
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:135	RQTQVGGTF	0.9969	0.9278	10	19
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:33	RQTQVGGTF	0.9969	0.905	10	19
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:34	RQTQVGGTF	0.9969	0.905	10	19
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:125	RQTQVGGTF	0.9969	0.905	10	19
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:27	RQTQVGGTF	0.9968	0.9155	10	19
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:24	RQTQVGGTF	0.9935	0.9223	10	19
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:50	RQTQVGGTF	0.9925	0.8936	10	19
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:50	TQVGGTFRM	0.9872	0.8879	12	21
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:53	TQVGGTFRM	0.9789	0.8843	12	21
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:12	RQTQVGGTF	0.9486	0.8529	10	19
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:73	TQVGGTFRM	0.9394	0.8824	12	21
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:12	TQVGGTFRM	0.8966	0.8019	12	21
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:35	RQTQVGGTF	0.8941	0.8119	10	19
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:54	TQVGGTFRM	0.8795	0.8649	12	21
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B39:02	TQVGGTFRM	0.879	0.887	12	21
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:53	RQTQVGGTF	0.8629	0.8826	10	19
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B39:31	TQVGGTFRM	0.8607	0.8352	12	21
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:68	TQVGGTFRM	0.8576	0.6088	12	21
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:30	TQVGGTFRM	0.8362	0.8977	12	21
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B40:49	TQVGGTFRM	0.8239	0.5017	12	21
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B40:21	TQVGGTFRM	0.821	0.6046	12	21
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:54	RQTQVGGTF	0.8167	0.8595	10	19
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B40:12	TQVGGTFRM	0.7935	0.5274	12	21
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:39	RQTQVGGTF	0.7622	0.8795	10	19
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:68	RQTQVGGTF	0.7532	0.544	10	19
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B48:02	TQVGGTFRM	0.7463	0.9208	12	21
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:20	TQVGGTFRM	0.7432	0.9291	12	21
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B35:28	TQVGGTFRM	0.7406	0.937	12	21
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:73	RQTQVGGTF	0.7309	0.8818	10	19
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-A32:01	RQTQVGGTF	0.7172	0.9168	10	19
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B35:20	TQVGGTFRM	0.7165	0.9414	12	21
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:30	RQTQVGGTF	0.6009	0.8789	10	19
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:09	TQVGGTFRM	0.4	0.8585	12	21
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B40:21	RQTQVGGTF	0.3685	0.5334	10	19
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:20	RQTQVGGTF	0.2672	0.9518	10	19
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B39:02	RQTQVGGTF	0.2672	0.9153	10	19
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B35:28	RQTQVGGTF	0.2374	0.9571	10	19
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B48:02	RQTQVGGTF	0.2364	0.9453	10	19
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:135	TQVGGTFRMF	0.9999	0.864	12	22
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:33	TQVGGTFRMF	0.9999	0.8661	12	22
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:27	TQVGGTFRMF	0.9999	0.9118	12	22
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:125	TQVGGTFRMF	0.9999	0.8661	12	22
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:34	TQVGGTFRMF	0.9999	0.8661	12	22
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:24	TQVGGTFRMF	0.9998	0.9371	12	22
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:50	TQVGGTFRMF	0.9998	0.8982	12	22
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:53	TQVGGTFRMF	0.9998	0.862	12	22
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:68	TQVGGTFRMF	0.9987	0.5613	12	22
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:54	TQVGGTFRMF	0.9985	0.832	12	22
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B27:06	HRQTQVGGTF	0.9984	0.5301	9	19
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:12	TQVGGTFRMF	0.991	0.766	12	22
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B48:02	TQVGGTFRMF	0.9763	0.9202	12	22
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:54	HRQTQVGGTF	0.9609	0.7764	9	19
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:20	TQVGGTFRMF	0.9301	0.9339	12	22
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B35:28	TQVGGTFRMF	0.9121	0.9394	12	22
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:53	HRQTQVGGTF	0.8568	0.8014	9	19
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:27	HRQTQVGGTF	0.8477	0.8686	9	19
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:34	HRQTQVGGTF	0.8433	0.8521	9	19
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:125	HRQTQVGGTF	0.8433	0.8521	9	19
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:33	HRQTQVGGTF	0.8433	0.8521	9	19
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:24	HRQTQVGGTF	0.8173	0.9044	9	19
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B15:12	HRQTQVGGTF	0.7372	0.7819	9	19
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	HLA-B38:05	QHRQTQVGGTF	0.9793	0.9545	8	19

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Potential FusionNeoAntigen Information of TLK2-SLC38A10 in HLA II

TLK2-SLC38A10_60629758_79256132.msa

Potential FusionNeoAntigen Information
* We used NetMHCIIpan v4.1 (%rank<0.5).

Fusion gene	Hchr	Hbp	Tgene	Tchr	Tbp	HLA II	FusionNeoAntigen peptide	Neoantigen start (at BP 13)	Neoantigen end (at BP 13)
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-0437	QISIQHRQTQVGGTF	4	19
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-0437	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-0804	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-0804	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-0804	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-0806	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-0810	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-0820	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-0820	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-0820	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-0828	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-0828	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-0828	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-0831	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-0831	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-0831	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1101	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1102	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1102	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1102	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1102	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1103	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1103	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1103	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1103	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1104	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1104	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1104	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1104	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1106	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1106	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1106	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1106	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1108	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1108	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1109	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1110	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1111	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1111	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1112	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1113	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1113	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1113	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1113	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1114	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1114	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1115	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1116	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1116	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1116	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1116	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1117	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1118	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1118	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1118	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1118	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1119	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1119	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1120	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1120	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1121	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1121	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1121	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1121	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1124	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1125	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1125	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1125	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1125	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1127	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1128	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1129	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1131	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1131	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1132	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1133	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1134	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1134	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1134	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1134	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1135	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1135	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1135	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1135	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1136	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1136	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1136	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1136	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1137	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1138	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1138	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1138	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1138	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1139	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1141	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1141	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1141	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1141	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1142	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1142	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1142	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1142	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1143	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1143	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1143	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1143	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1144	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1144	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1144	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1144	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1145	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1146	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1146	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1146	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1146	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1147	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1147	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1147	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1147	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1148	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1148	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1148	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1148	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1149	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1150	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1150	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1150	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1150	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1151	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1152	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1154	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1154	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1155	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1155	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1155	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1155	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1156	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1156	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1156	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1156	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1157	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1157	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1157	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1157	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1158	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1158	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1158	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1158	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1159	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1159	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1159	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1159	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1160	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1160	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1160	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1160	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1161	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1162	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1163	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1163	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1163	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1163	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1164	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1165	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1165	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1165	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1165	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1166	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1167	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1167	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1167	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1168	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1168	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1169	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1169	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1170	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1170	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1170	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1170	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1172	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1172	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1173	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1173	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1174	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1175	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1176	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1176	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1176	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1176	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1177	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1177	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1177	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1177	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1178	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1178	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1178	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1178	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1179	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1179	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1180	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1180	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1181	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1182	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1182	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1183	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1183	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1183	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1183	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1184	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1184	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1184	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1184	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1185	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1185	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1185	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1185	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1186	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1186	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1187	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1187	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1188	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1188	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1188	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1188	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1189	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1189	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1190	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1191	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1192	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1192	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1192	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1192	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1193	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1193	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1194	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1195	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1196	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1204	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1209	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1301	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1301	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1301	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1301	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1302	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1302	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1304	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1304	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1304	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1304	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1305	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1306	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1306	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1306	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1306	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1307	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1308	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1308	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1308	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1308	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1309	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1309	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1309	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1309	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1311	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1311	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1311	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1311	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1314	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1315	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1315	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1315	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1315	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1316	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1316	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1317	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1317	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1317	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1317	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1318	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1318	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1318	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1318	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1319	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1319	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1319	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1319	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1320	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1320	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1320	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1320	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1322	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1322	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1322	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1322	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1323	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1323	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1324	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1324	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1324	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1324	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1326	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1327	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1327	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1327	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1327	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1329	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1329	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1332	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1332	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1332	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1332	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1334	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1334	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1335	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1335	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1335	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1335	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1336	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1336	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1337	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1337	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1338	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1339	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1339	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1341	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1341	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1342	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1342	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1342	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1342	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1343	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1343	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1343	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1343	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1344	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1344	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1344	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1344	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1348	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1348	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1348	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1348	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1350	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1351	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1351	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1351	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1351	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1352	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1352	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1352	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1352	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1353	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1353	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1353	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1353	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1354	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1354	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1356	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1356	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1357	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1357	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1357	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1357	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1358	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1359	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1359	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1359	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1359	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1360	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1361	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1361	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1361	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1361	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1362	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1363	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1363	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1364	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1364	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1364	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1364	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1365	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1368	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1368	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1368	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1368	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1369	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1369	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1369	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1369	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1370	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1370	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1370	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1370	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1371	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1371	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1371	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1371	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1372	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1372	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1372	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1372	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1373	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1373	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1374	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1374	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1375	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1375	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1375	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1375	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1376	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1376	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1376	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1376	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1377	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1378	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1378	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1378	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1378	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1379	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1379	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1379	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1379	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1380	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1380	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1380	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1380	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1381	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1381	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1382	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1382	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1383	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1383	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1383	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1383	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1384	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1384	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1384	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1384	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1385	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1385	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1386	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1386	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1387	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1387	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1387	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1387	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1389	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1389	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1391	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1391	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1391	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1391	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1392	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1392	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1392	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1392	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1393	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1393	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1393	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1393	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1394	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1394	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1394	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1396	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1397	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1397	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1398	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1398	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1398	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1398	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1399	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1399	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1402	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1403	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1405	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1406	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1406	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1406	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1406	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1408	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1409	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1409	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1411	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1412	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1412	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1412	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1412	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1415	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1415	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1415	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1416	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1416	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1416	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1417	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1417	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1417	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1417	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1418	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1418	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1419	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1420	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1420	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1420	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1420	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1421	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1421	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1421	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1421	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1423	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1424	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1424	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1429	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1429	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1429	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1429	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1430	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1430	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1432	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1433	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1433	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1433	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1434	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1434	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1434	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1437	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1437	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1437	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1437	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1440	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1441	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1443	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1445	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1452	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1452	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1456	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1459	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1464	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1464	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1465	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1465	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1465	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1472	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1472	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1474	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1474	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1477	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1478	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1478	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1480	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1480	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1480	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1480	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1481	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1481	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1481	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1481	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1483	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1483	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1483	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1483	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1484	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1484	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1484	KQISIQHRQTQVGGT	3	18
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1484	SSQKQISIQHRQTQV	0	15
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1491	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1494	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1495	QKQISIQHRQTQVGG	2	17
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1495	SQKQISIQHRQTQVG	1	16
TLK2-SLC38A10	chr17	60629758	chr17	79256132	895	DRB1-1496	QKQISIQHRQTQVGG	2	17

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Fusion breakpoint peptide structures of TLK2-SLC38A10

3D structures of the fusion breakpoint peptide of 14AA sequence that have potential fusion neoantigens
* The minimum length of the amino acid sequence in RoseTTAFold is 14AA. Here, we predicted the 14AA fusion protein breakpoint sequence not the fusion neoantigen peptide, which is shorter than 14 AA.

File name	BPseq	Hgene	Tgene	Hchr	Hbp	Tchr	Tbp	AAlen
8668	SIQHRQTQVGGTFR	TLK2	SLC38A10	chr17	60629758	chr17	79256132	895

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Filtering FusionNeoAntigens Through Checking the Interaction with HLAs in 3D of TLK2-SLC38A10

Virtual screening between 25 HLAs (from PDB) and FusionNeoAntigens
* We used Glide to predict the interaction between HLAs and neoantigens.

HLA allele	PDB ID	File name	BPseq	Docking score	Glide score
HLA-B52:01	3W39	8668	SIQHRQTQVGGTFR	-6.6926	-6.6926
HLA-B44:05	3DX8	8668	SIQHRQTQVGGTFR	-5.33473	-5.33473

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Vaccine Design for the FusionNeoAntigens of TLK2-SLC38A10

mRNA and peptide sequences of FusionNeoAntigens that have potential interaction with HLA-Is.

Fusion gene	Hchr	Hbp	Tchr	Tbp	Start in +/-13AA	End in +/-13AA	FusionNeoAntigen peptide sequence	FusionNeoAntigen RNA sequence
TLK2-SLC38A10	chr17	60629758	chr17	79256132	10	19	RQTQVGGTF	CAGACCCAGGTGGGCGGCACCTTCCGC
TLK2-SLC38A10	chr17	60629758	chr17	79256132	12	21	TQVGGTFRM	CAGGTGGGCGGCACCTTCCGCATGTTC
TLK2-SLC38A10	chr17	60629758	chr17	79256132	12	22	TQVGGTFRMF	CAGGTGGGCGGCACCTTCCGCATGTTCCTG
TLK2-SLC38A10	chr17	60629758	chr17	79256132	6	15	SIQHRQTQV	ATCCAGCACAGACAGACCCAGGTGGGC
TLK2-SLC38A10	chr17	60629758	chr17	79256132	7	15	IQHRQTQV	CAGCACAGACAGACCCAGGTGGGC
TLK2-SLC38A10	chr17	60629758	chr17	79256132	8	19	QHRQTQVGGTF	CACAGACAGACCCAGGTGGGCGGCACCTTCCGC
TLK2-SLC38A10	chr17	60629758	chr17	79256132	9	19	HRQTQVGGTF	AGACAGACCCAGGTGGGCGGCACCTTCCGC

mRNA and peptide sequences of FusionNeoAntigens that have potential interaction with HLA-IIs.

Fusion gene	Hchr	Hbp	Tchr	Tbp	Start in +/-13AA	End in +/-13AA	FusionNeoAntigen peptide	FusionNEoAntigen RNA sequence
TLK2-SLC38A10	chr17	60629758	chr17	79256132	0	15	SSQKQISIQHRQTQV	TCCCAAAAACAGATCTCCATCCAGCACAGACAGACCCAGGTGGGC
TLK2-SLC38A10	chr17	60629758	chr17	79256132	1	16	SQKQISIQHRQTQVG	CAAAAACAGATCTCCATCCAGCACAGACAGACCCAGGTGGGCGGC
TLK2-SLC38A10	chr17	60629758	chr17	79256132	2	17	QKQISIQHRQTQVGG	AAACAGATCTCCATCCAGCACAGACAGACCCAGGTGGGCGGCACC
TLK2-SLC38A10	chr17	60629758	chr17	79256132	3	18	KQISIQHRQTQVGGT	CAGATCTCCATCCAGCACAGACAGACCCAGGTGGGCGGCACCTTC
TLK2-SLC38A10	chr17	60629758	chr17	79256132	4	19	QISIQHRQTQVGGTF	ATCTCCATCCAGCACAGACAGACCCAGGTGGGCGGCACCTTCCGC

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Information of the samples that have these potential fusion neoantigens of TLK2-SLC38A10

These samples were reported as having these fusion breakpoints. For individual breakpoints, we checked the open reading frames considering multiple gene isoforms and chose the in-frame fusion genes only. Then, we made fusion protein sequences and predicted the fusion neoantigens. These fusion-positive samples may have these potential fusion neoantigens.

Cancer type	Fusion gene	Hchr	Hbp	Henst	Tchr	Tbp	Tenst	Sample
ESCA	TLK2-SLC38A10	chr17	60629758	ENST00000326270	chr17	79256132	ENST00000288439	TCGA-2H-A9GK

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Potential target of CAR-T therapy development for TLK2-SLC38A10

Predicted 3D structure. We used RoseTTAFold.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, to provide the retention of the transmembrane domain, we only show the protein feature retention information of those transmembrane features

* Minus value of BPloci means that the break point is located before the CDS.

- In-frame and retained 'Transmembrane'.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

SLC38A10

chr17:60629758

chr17:79256132

ENST00000288439

120_140

781.0

Transmembrane

Helical

Tgene

SLC38A10

chr17:60629758

chr17:79256132

ENST00000288439

153_173

781.0

Transmembrane

Helical

Tgene

SLC38A10

chr17:60629758

chr17:79256132

ENST00000288439

229_249

781.0

Transmembrane

Helical

Tgene

SLC38A10

chr17:60629758

chr17:79256132

ENST00000288439

272_292

781.0

Transmembrane

Helical

Tgene

SLC38A10

chr17:60629758

chr17:79256132

ENST00000288439

323_343

781.0

Transmembrane

Helical

Tgene

SLC38A10

chr17:60629758

chr17:79256132

ENST00000288439

345_365

781.0

Transmembrane

Helical

Tgene

SLC38A10

chr17:60629758

chr17:79256132

ENST00000288439

378_398

781.0

Transmembrane

Helical

Tgene

SLC38A10

chr17:60629758

chr17:79256132

ENST00000374759

120_140

1120.0

Transmembrane

Helical

Tgene

SLC38A10

chr17:60629758

chr17:79256132

ENST00000374759

153_173

1120.0

Transmembrane

Helical

Tgene

SLC38A10

chr17:60629758

chr17:79256132

ENST00000374759

229_249

1120.0

Transmembrane

Helical

Tgene

SLC38A10

chr17:60629758

chr17:79256132

ENST00000374759

272_292

1120.0

Transmembrane

Helical

Tgene

SLC38A10

chr17:60629758

chr17:79256132

ENST00000374759

323_343

1120.0

Transmembrane

Helical

Tgene

SLC38A10

chr17:60629758

chr17:79256132

ENST00000374759

345_365

1120.0

Transmembrane

Helical

Tgene

SLC38A10

chr17:60629758

chr17:79256132

ENST00000374759

378_398

1120.0

Transmembrane

Helical

Subcellular localization prediction of the transmembrane domain retained fusion proteins
* We used DeepLoc 1.0. The order of the X-axis of the barplot is as follows: Entry_ID, Localization, Type, Nucleus, Cytoplasm, Extracellular, Mitochondrion, Cell_membrane, Endoplasmic_reticulum, Plastid, Golgi.apparatus, Lysosome.Vacuole, Peroxisome. Y-axis is the output score of DeepLoc. Clicking the image will open a new tab with a large image.

Hgene

Hchr

Hbp

Henst

Tgene

Tchr

Tbp

Tenst

DeepLoc result

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Related Drugs to TLK2-SLC38A10

Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene

Tgene

Drug

Source

PMID

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Related Diseases to TLK2-SLC38A10

Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene

Tgene

Disease

Source

PMID

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source

	Fusion Gene and Fusion Protein Summary
	Fusion Amino Acid Sequences (multiple BPs and multiple gene isoforms)
	Fusion Protein Breakpoint Sequences - (for the Screening of the FusionNeoAntigens)
	Potential FusionNeoAntigens in HLA I - (netMHCpan v4.1 + deepHLApan v1.1)
	Potential FusionNeoAntigens in HLA II - (netMHCIIpan v4.1)
	Fusion Breakpoint 14 AA Peptide Structure - (RoseTTAFold)
	Filtering FusionNeoAntigens Through Checking the Interaction with HLAs in 3D - (Glide)
	Vaccine Design for the FusionNeoAntigens (RNA/protein sequences)
	Potential target of CAR-T therapy development
	Information on the samples that have these potential fusion neoantigens
	Fusion Protein Targeting Drugs - (Manual Curation)
	Fusion Protein Related diseases - (Manual Curation)