UTHEALTH HOME    ABOUT SBMI    A-Z    WEBMAIL    INSIDE THE UNIVERSITY
FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact

Terms of Use
Center for Computational Systems Medicine
leaf

Kinase Fusion Gene Summary

leaf

Kinase Fusion Gene Sample Information

leaf

Kinase Fusion ORF Analysis

leaf

Kinase Fusion Amino Acid Sequences

leaf

Multiple Sequence Alignment of All Fusion Protein Isoforms

leaf

Kinase Fusion Protein Functional Features

leaf

Kinase Fusion Protein Structures

leaf

Comparison of Fusion Protein Isoforms

leaf

Comparison of Fusion Protein Sequences/Structures with Known Sequences/Structures from PDB

leaf

pLDDT Scores and Difference Analysis of pLDDT Scores Between the Active Sites (Best) and Non-Active Sites.

leaf

Ramachandran Plot of Kinase Fusion Protein Structure

leaf

Potential Active Site Information

leaf

Virtual Screening Results

leaf

Kinase-Substrate Information

leaf

Related Drugs with This Kinase Fusion Protein

leaf

Related Disease with This Kinase Fusion Protein

leaf

Clinical Trials of the Found Drugs/Small Molecules

Kinase Fusion Gene:CDK1_ASS1

Kinase Fusion Protein Summary

check button Kinase Fusion gene summary
Kinase Fusion partner gene informationKinase Fusion gene name: CDK1_ASS1
KinaseFusionDB ID: KFG1147
FusionGDB2.0 ID: KFG1147
HgeneTgene
Gene symbol

CDK1

ASS1

Gene ID

983

445

Gene namecyclin dependent kinase 1argininosuccinate synthase 1
SynonymsCDC2|CDC28A|P34CDC2ASS|CTLN1
Cytomap

10q21.2

9q34.11

Type of geneprotein-codingprotein-coding
Descriptioncyclin-dependent kinase 1cell cycle controller CDC2cell division control protein 2 homologcell division cycle 2, G1 to S and G2 to Mcell division protein kinase 1p34 protein kinaseargininosuccinate synthaseargininosuccinate synthetase 1citrulline-aspartate ligaseepididymis secretory sperm binding protein
Modification date2024041320240407
UniProtAcc

Q9BWU1

P00966

Ensembl transtripts involved in fusion geneENST idsENST00000519760, ENST00000316629, 
ENST00000395284, ENST00000373809, 
ENST00000448257, 		ENST00000352480, 
ENST00000372393, ENST00000372394, 
ENST00000493984, 
Context (manual curation of fusion genes in KinaseFusionDB)

PubMed: CDK1 [Title/Abstract] AND ASS1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)CDK1(62538236)-ASS1(133366542), # samples:2
check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCDK1

GO:0000086

G2/M transition of mitotic cell cycle

2188730|2344612|30139873

HgeneCDK1

GO:0006468

protein phosphorylation

23509069|23574715|30723163

HgeneCDK1

GO:0007077

mitotic nuclear membrane disassembly

2188730

HgeneCDK1

GO:0018105

peptidyl-serine phosphorylation

11298763

HgeneCDK1

GO:0018107

peptidyl-threonine phosphorylation

11298763

HgeneCDK1

GO:0034501

protein localization to kinetochore

18195732

HgeneCDK1

GO:0043066

negative regulation of apoptotic process

11069302

HgeneCDK1

GO:0062033

positive regulation of mitotic sister chromatid segregation

26829474

HgeneCDK1

GO:1902850

microtubule cytoskeleton organization involved in mitosis

10791892

TgeneASS1

GO:0007623

circadian rhythm

28985504


check buttonKinase Fusion gene breakpoints across CDK1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonKinase Fusion gene breakpoints across ASS1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.


Top

Kinase Fusion Gene Sample Information

check buttonKinase Fusion gene information.
check button Kinase Fusion gene information from four resources (ChiTars 5.0, ChimerDB 4.0, COSMIC, and CCLE)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceSampleHgeneHchrHbpTgeneTchrTbp
ChiTaRS5.0AX184499CDK1chr10

62538236

ASS1chr9

133366542



Top

Kinase Fusion ORF Analysis


check buttonKinase Fusion information from ORFfinder translation from full-length transcript sequence from KinaseFusionDB.
HenstTenstHgeneHchrHbpTgeneTchrTbpSeq length
(transcript)		Seq length
(amino acids)

Top

Kinase Fusion Amino Acid Sequences


check button For individual full-length fusion transcript sequence from KinaseFusionDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>Henst_Tenst_Hgene_Hchr_Hbp_Tgene_Tchr_Tbp_length(fusion AA)_AAseq

Multiple Sequence Alignment of All Fusion Protein Isoforms



Top

Kinase Fusion Protein Functional Features


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/:62538236/:133366542)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CDK1

Q9BWU1

ASS1

P00966

FUNCTION: One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues. {ECO:0000305|PubMed:18473344, ECO:0000305|PubMed:27287393, ECO:0000305|PubMed:8792870}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

* Minus value of BPloci means that the break pointn is located before the CDS.

check button - Retained domain in the 5'-partner of fusion protein (protein functional feature from UniProt).
PartnerHgeneeneHbpTgeneeneTbpENSTBPexonTotalExonProtein feature lociBPlociTotalLenFeatureNote


check button - Retained domain in the 3'-partner of fusion protein (protein functional feature from UniProt).
PartnerHgeneeneHbpTgeneeneTbpENSTBPexonTotalExonProtein feature lociBPlociTotalLenFeatureNote


Top

Kinase-Substrate Information of CDK1_ASS1


check button Phosphorylation target of the kinase
(phosphosite, 03-17-2024)
KinaseKinase UniProt AccKinase speciesSubstrateSubstrate UniProt AccSubstrate phosphorylated residuesSubstrate phosphorylated sites (+/-7AA)Domain
CDK1P06493humanTRIM32Q13049S335sPEEVVAsPRAsPAk
CDK1P06493humanMDM4O15151S96SFSVkDPsPLyDMLR
CDK1P06493humanKPNA2P52292S62sFPDDAtsPLQENRNIBB
CDK1P06493humanNUMA1Q14980T2055MAFsILNtPkkLGNs
CDK1P06493humanMAPTP10636-8T231KKVAVVRtPPKsPss
CDK1P06493humanNDE1Q9NXR1-1S282RNLVyDQsPNRtGGPNUDE_C
CDK1P06493humanNCLP19338T121PGkALVAtPGkkGAA
CDK1P06493humanSASS6Q6UVJ0T495DVLGPSTtPPAHsSS
CDK1P06493humanSIRT3Q9NTG7S159SGIPDFRsPGSGLYSSIR2
CDK1P06493humanNDUFB6O95139S29WLkDQELsPREPVLPNDUF_B6
CDK1P06493humanARHGAP19Q14CB8T404NkQSLTQtPGREPST
CDK1P06493humanCHEK1O14757S286tsGGVsEsPsGFskH
CDK1P06493humanCLASP2O75122S507QGCsREAsPsRLsVA
CDK1P06493humanNOLC1Q14978T607AkKIkLQtPNtFPKR
CDK1P06493humanATG13O75143T342DRTHCAAtPSSSEDT
CDK1P06493humanEPB41P11171-2T60LKASNGDtPTHEDLT
CDK1P06493humanITPR1Q14643T800RDPQEQVtPVKYARL
CDK1P06493humanARHGEF2Q92974S960sRLsPPHsPRDFTRM
CDK1P06493humanRANGAP1P46060T409GQGEkSAtPSRkILDRanGAP1_C
CDK1P06493humanVGLL4Q14135-4T159AGLsPTLtPGERQQNVGLL4
CDK1P06493humanSRRM2Q9UQ35T1413VLDAVPRtPsRERss
CDK1P06493humanCDC27P30260T209LtEtPQDtIELNRLN
CDK1P06493humanNDUFB6O95139T5___MtGYtPDEkLRLNDUF_B6
CDK1P06493humanGJA1P17302S255HAtsGALsPAkDCGs
CDK1P06493humanYAP1P46937S367GtQNPVssPGMsQEL
CDK1P06493humanAMPHP49418S285NHTLAPAsPAPARPR
CDK1P06493humanRPS6KB1P23443S447GsPRtPVsPVkFsPG
CDK1P06493humanKMT2EQ8IZD2T912PMDPSFAtPPRIKSD
CDK1P06493humanRGPD4Q7Z3J3S1276HAsPLAssPVRKNLF
CDK1P06493humanHMGA1P17096T78ktrkttttPGrkPrG
CDK1P06493humanMAPK6Q16659S688QFHsPVGsPLkSIQA
CDK1P06493humanTCOF1Q13428T983AQAQAAstPRKARAS
CDK1P06493humanHMGCS1Q01581S495IATEHIPsPAkkVPR
CDK1P06493humanMASTLQ96GX5S875tAQHLtVsGFsL___
CDK1P06493humanSLBPQ14493T62RRPEsFttPEGPkPR
CDK1P06493humanDNM2P50570S764LQsAssHsPtPQRRP
CDK1P06493humanMORC2Q9Y6X9T717PsPkVIKtPVVKKtE
CDK1P06493humanVGLL4Q14135-4S280SRRGQPAsPSAHMVS
CDK1P06493humanPPP1R13LQ8WUF5S113LHPysPLsPKGrPss
CDK1P06493humanYAP1P46937S217MNVTAPTsPPVQQNM
CDK1P06493humanFOXO1Q12778S249EGGkSGksPrRrAAs
CDK1P06493humanZC3HC1Q86WB0S395PGLEVPssPLRKAKR
CDK1P06493humanSP1P08047T737AGsEGSGtAtPSALI
CDK1P06493humanPPP1CAP62136T320NPGGRPItPPRNsAK
CDK1P06493humanKIF20AO95235S867CQsstDCsPyARILR
CDK1P06493humanNUMA1Q14980T2106tAAAIGAtPRAKGKA
CDK1P06493humanCDC25AP30304S283PErsQEEsPPGSTKrM-inducer_phosp
CDK1P06493humanMAPK6Q16659S684IGIPQFHsPVGsPLk
CDK1P06493humanCENPAP49450S68LIRKLPFsRLAREICHistone
CDK1P06493humanDLGAP5Q15398S839GGNLItFsPLQPGEF
CDK1P06493humanPHLPP1O60346S411LPLPQtAssPQPQQK
CDK1P06493humanTP53BP1Q12888S1678ItsEEERsPAKRGRK
CDK1P06493humanNIFKQ9BYG3T238QGPtPVCtPtFLERRhNIFK_binding
CDK1P06493humanTP73O15350T86AASASPYtPEHAASV
CDK1P06493humanUBE2IP63279S71FkDDYPssPPkCKFEUQ_con
CDK1P06493humanAJUBAQ96IF1S175GyDQRHGsPLPAGPC
CDK1P06493humanCASP9P55211T125PEVLRPEtPRPVDIG
CDK1P06493humanCDCA5Q96FF9S126NPEAEsssKEGELDASororin
CDK1P06493humanNCKAP5LQ9HCH0S440KLQIGPPsPGEAQGP
CDK1P06493humanCDC16Q13042S112EkYLkDEsGFkDPSS
CDK1P06493humanUSP1O94782S313AtsDtLEsPPKIIPKUCH
CDK1P06493humanTCOF1Q13428S583LQAkPtssPAKGPPQTreacle
CDK1P06493humanTK1P04183S13LPtVLPGsPskTRGQ
CDK1P06493humanMARK2Q7KZI7S569PQRVPVAsPsAHNIs
CDK1P06493humanTSC1Q92574T1047SSSSELstPEKPPHQ
CDK1P06493humanCTDSPL2Q05D32T86DNNLITstPRAGEKP
CDK1P06493humanCDCA5Q96FF9T111ktHsVPAtPtStPVPSororin
CDK1P06493humanRAP1GAPP47736S484SLIVPGKsPtRKKsG
CDK1P06493humanKIF2CQ99661T537LGQNkAHtPFRESkLKinesin
CDK1P06493humanCC2D1AQ6P1N0S208PAstPtysPAPtQPA
CDK1P06493humanKAT5Q92993S86TKNGLPGsRPGsPER
CDK1P06493humanFOXK2Q01167S373sSRsAPAsPNHAGVL
CDK1P06493humanGMPSP49915T318PIsDEDRtPRKRISkNAD_synthase
CDK1P06493humanDUTP33316-2S11sEEtPAIsPskRARP
CDK1P06493humanDAB2IPQ5VWQ8-2T546GTNDLAStPGSGSSSDUF3498
CDK1P06493humanUGDHO60701T461TIGFQIEtIGKKVSS
CDK1P06493humanEIF2AK2P19525S83NkEKkAVsPLLLttt
CDK1P06493humanRUNX1Q01196-8S276DTRQIQPsPPWSYDQ
CDK1P06493humanEIF4G1Q04637S1231EAALPPVsPLkAALs
CDK1P06493humanIREB2P48200S157LQkAGkLsPLkVQPK
CDK1P06493humanWWTR1Q9GZV5T285AVNPPTMtPDMRsIT
CDK1P06493humanTASORQ9UK61T819HEyELNStPDKKDyE
CDK1P06493humanNCOA1Q15788T1426KPTSGPQtPQAQQKS
CDK1P06493humanRUNX1Q01196-8S48TPPSTALsPGKMSEA
CDK1P06493humanCHMP7Q8WUX9S441GLVPSsKsPKRQLEPSnf7
CDK1P06493humanDENRO43583S73AKLtVENsPKQEAGI
CDK1P06493humanNDUFA12Q9UI09T120HKFNVTGtPEQYVPYNDUFA12
CDK1P06493humanFOXM1Q08050T611ETLPISstPSkSVLP
CDK1P06493humanLMNB1P20700S393ErLkLsPsPssRVtV
CDK1P06493humanRCC1P18754T274SNYHQLGtPGTESCFRCC1
CDK1P06493humanKIF22Q14807S427AsAsQkLsPLQkLSs
CDK1P06493humanLMNAP02545T19sGAQAsstPLsPtRI
CDK1P06493humanCDC14AQ9UNH5S453KtSKMALsPSATAKR
CDK1P06493humanRPA2P15927S29QsPGGFGsPAPsQAE
CDK1P06493humanCDKN2DP55273S76VQDTSGTsPVHDAARAnk_2
CDK1P06493humanFLNAP21333S1630GGDEIPFsPyRVRAVFilamin
CDK1P06493humanTOP2AP11388S1247kNENtEGsPQEDGVE
CDK1P06493humanCDC14AQ9UNH5S411SQRQPRTsPSCAFRS
CDK1P06493humanANAPC1Q9H1A4T537tPLDGVstPkPLsKL
CDK1P06493humanBLMP54132S714PGVTVVIsPLRSLIVDEAD
CDK1P06493humanTERF1P54274T371VSKsQPVtPEKHRAR
CDK1P06493humanCDC25BP30305S321KCQRLFRsPsMPCsVM-inducer_phosp
CDK1P06493humanLIMD1Q9UGP4S277RVsPGLPsPNLENGA
CDK1P06493humanARP10275S310TEDTAEysPFKGGYTAndrogen_recep
CDK1P06493humanLIMD1Q9UGP4S272TASsQRVsPGLPsPN
CDK1P06493humanCDC16Q13042S560kTLkNIIsPPWDFRE
CDK1P06493humanANAPC1Q9H1A4S377NIssHNQsPkRHSIS
CDK1P06493humanKIF20AO95235S878RILRsRRsPLLKsGP
CDK1P06493humanCREMQ03060S277AsPGsLHsPQQLAEE
CDK1P06493humanMAP4P27816S696PNKELPPsPEKKTkP
CDK1P06493humanKIF20AO95235S532KEHsLQVsPSLEkGA
CDK1P06493humanSKA3Q8IX90T358SYENLLRtPtPPEVT
CDK1P06493humanDIAPH1O60610T768PVLPFGLtPKkLykP
CDK1P06493humanDLG1Q12959S443FLGQtPAsPARysPVPDZ_assoc
CDK1P06493humanCENPCQ03188T734kLVLPsNtPNVRRTK
CDK1P06493humanATG13O75143S44ICTRSSSsPTGSDWF
CDK1P06493humanCDC25CP30307S122DQHLMKCsPAQLLCS
CDK1P06493humanCSNK2A1P68400T344SSMPGGStPVSSANM
CDK1P06493humanMTHFRP42898T34KDSSRCStPGLDPER
CDK1P06493humanMCL1Q07820S64IGGSAGAsPPStLtP
CDK1P06493humanKIF22Q14807T463QGAPLLstPkRERMV
CDK1P06493humanCDC25CP30307S168SEMKyLGsPIttVPK
CDK1P06493humanAKT1P31749S473RPHFPQFsysAsGtAPkinase_C
CDK1P06493humanUSP24Q9UPU5S2604HLQQGsEsPMMIGEL
CDK1P06493humanRUNX1Q01196-8T300sPSVHPAtPIsPGRA
CDK1P06493humanRPTORQ8N122S696EKNyALPsPAttEGG
CDK1P06493humanCDC27P30260T289FGILPLEtPsPGDGs
CDK1P06493humanUIMC1Q96RL1S677TRRDLNEsPVksFVS
CDK1P06493humanPHLPP1O60346S321RRAsPAPsDssPGEP
CDK1P06493humanCDK7P50613T170GsPNRAytHQVVtRWPkinase
CDK1P06493humanCDCA5Q96FF9S21RsGPRAPsPtKPLRR
CDK1P06493humanNINLQ9Y2I6S589NRHsPSWsPDGRRRQ
CDK1P06493humanMAPTP10636-8S404PVVsGDtsPRHLsNV
CDK1P06493humanWWTR1Q9GZV5T346TGENAGQtPMNINPQ
CDK1P06493humanDLGAP5Q15398S618AGFFRVEsPVKLFsG
CDK1P06493humanAJUBAQ96IF1S119EPTAPALsPRSsFAs
CDK1P06493humanMKI67P46013T761GIAEMFktPVkEQPQ
CDK1P06493humanODF2Q5BJF6-3S796YSTFLTSsPIRSRSP
CDK1P06493humanIL16Q14005T757TQGHPDGtPPKLDTA
CDK1P06493humanSCML2Q9UQR0T305SssVkNItPRKKGPNRBR
CDK1P06493humanNEDD1Q8NHV4S411ssLGDMFsPIRDDAV
CDK1P06493humanUSP9XQ93008S2547yEGsEEVsPPQtKDQ
CDK1P06493humanCDT1Q9H211T402PrPALPAtPPAtPPA
CDK1P06493humanPHLPP1O60346S335PFVGGPVssPRAPRP
CDK1P06493humanKIF20AO95235S7_MsQGILsPPAGLLs
CDK1P06493humanRBBP8Q99708S327ELPtRVssPVFGATS
CDK1P06493humanPKN2Q16513S535VNHsGtFsPQAPVPT
CDK1P06493humanCDC25AP30304S18RRLLFACsPPPASQP
CDK1P06493humanCARHSP1Q9Y2V2T23AsVGLLDtPRsRERs
CDK1P06493humanCDC25BP30305-2S146PVRLLGHsPVLRNITM-inducer_phosp
CDK1P06493humanAMPHP49418S272EEPsPLPsPTAsPNH
CDK1P06493humanATG13O75143T332QERLATCtPsDRTHC
CDK1P06493humanVIMP08670S55tsrsLyAssPGGVyAFilament_head
CDK1P06493humanFERMT1Q9BQL6S179TAsGsSVsPGLYSKT
CDK1P06493humanCCNB1P14635S126PILVDTAsPsPMETs
CDK1P06493humanBCL9O00512T172EPtPAQKtPAKVVYV
CDK1P06493humanNDEL1Q9GZM8S242IPNGFGtsPLtPSARNUDE_C
CDK1P06493humanDSN1Q9H410S331SMQQLDPsPARKLLkMIS13
CDK1P06493humanEEF1DP29692S133APQtQHVsPMRQVEP
CDK1P06493humanCDC25CP30307T67LsILsGGtPkRCLDL
CDK1P06493humanPHLPP1O60346S345RAPRPVVsDTESFSL
CDK1P06493humanBADQ92934S91EGMGEEPsPFrGrsRBcl-2_BAD
CDK1P06493humanMAP2K1Q02750T292EtPPRPRtPGRPLssPkinase
CDK1P06493humanARHGAP19Q14CB8T476GsPAVtMtPtRLKWS
CDK1P06493humanCSNK2A1P68400S362ISSVPtPsPLGPLAG
CDK1P06493humanRRM2P31350T33sLVdkENtPPALsGt
CDK1P06493humanSTMN1P16949S25QAFELILsPrskEsVStathmin
CDK1P06493humanSP1P08047S720GGPGVALsVGtLPLD
CDK1P06493humanNDUFS2O75306S364kVDDAKVsPPKRAEMComplex1_49kDa
CDK1P06493humanTCOF1Q13428S156ANLLsGksPRKsAEP
CDK1P06493humanCDC25AP30304S116PQkLLGCsPALkRSHM-inducer_phosp
CDK1P06493humanNDEL1Q9GZM8T219AsLsLPAtPVGKGTENUDE_C
CDK1P06493humanDDX3XO00571T323GCHLLVAtPGRLVDMDEAD
CDK1P06493humanRAD9AQ99638T355EPstVPGtPPPKKFR
CDK1P06493humanCTDSPL2Q05D32S134EDNPsSGsPPRTTLL
CDK1P06493humanTSC1Q92574S584ETsIFTPsPCKIPPPHamartin
CDK1P06493humanISL1P61371S269GTPMVAAsPERHDGG
CDK1P06493humanRUNX1Q01196-8S424SMVGGERsPPRILPPRunxI
CDK1P06493humanPOLR2AP24928S1920sPtysPtsPKysPtsRNA_pol_Rpb1_R; RNA_pol_Rpb1_R
CDK1P06493humanSCML2Q9UQR0S511VPyVVPLsPKLPKTk
CDK1P06493humanCDCA2Q69YH5T412DEsLPANtPLRKGGTPP1_bind
CDK1P06493humanORC6Q9Y5N6T195REPGDVAtPPRKRKk
CDK1P06493humanFERMT1Q9BQL6S176ssPTAsGsSVsPGLY
CDK1P06493humanCLASP2O75122S1012LHSMPtHssPRsRDy
CDK1P06493humanCTDSPL2Q05D32S104ISRVRRKsQVNGEAG
CDK1P06493humanCTTNQ14247S405KtQtPPVsPAPQPtE
CDK1P06493humanDDHD1Q8NEL9S8MNYPGrGsPRsPEHN
CDK1P06493humanHJURPQ8NCD3S473MYRGGPAsPGGLQGL
CDK1P06493humanNCAPD3P42695T1415VTkRAIstPEKsISD
CDK1P06493humanEIF4A3P38919T163GQHVVAGtPGRVFDMDEAD
CDK1P06493humanVCPIP1Q96JH7T761GPssAPAtPtkAPys
CDK1P06493humanRGPD6Q99666S1275HAsPLAssPVRKNLF
CDK1P06493humanMARK2Q7KZI7S456sTAKVPAsPLPGLER
CDK1P06493humanNPM1P06748T234sFkkQEKtPKtPkGP
CDK1P06493humanNCKAP5LQ9HCH0S477sPGGPQLsPQLPRNS
CDK1P06493humanCDCA5Q96FF9S181AEDLsGVsPVVCsKLSororin
CDK1P06493humanPHLPP1O60346T409QPLPLPQtAssPQPQ
CDK1P06493humanCLASP2O75122S1029yNysDsIsPFNKsAL
CDK1P06493humanPKN1Q16512S537GTFsPGAsPGsEART
CDK1P06493humanCUEDC2Q9H467S110VQGQVPIsPEPLQRP
CDK1P06493humanLIMD1Q9UGP4S421LGSVLLDsPssPRVr
CDK1P06493humanKHDRBS1Q07666T317rGALVrGtPVrGAIT
CDK1P06493humanEEF2P13639S595NVLCLsksPNkHNRL
CDK1P06493humanKHDRBS1Q07666T33AHPsVRQtPsrQPPL
CDK1P06493humanCDC25CP30307T130PAQLLCStPNGLDRG
CDK1P06493humanCDC23Q9UJX2T562QLRNQGEtPttEVPA
CDK1P06493humanUBXN2BQ14CS0S56PkATVFksPRtPPQR
CDK1P06493humanLATS1O95835T490ATTVTAItPAPIQQP
CDK1P06493humanNDC80O14777T31VNkQGLytPQTKEkP
CDK1P06493humanAAK1Q2M2I8T389LPIQPALtPrKRATV
CDK1P06493humanMCTS1Q9ULC4S118IMCPGLTsPGAKLyPPUA
CDK1P06493humanLIG3P49916T191LSSKAAGtPKKKAVV
CDK1P06493humanCDK7P50613S164GLAksFGsPNRAytHPkinase
CDK1P06493humanRGPD8O14715S1275HAsPLAssPVRKNLF
CDK1P06493humanCREMQ03060S271QGVVMAAsPGsLHsP
CDK1P06493humanKMT5AQ9NQR1S100SKIySyMsPNKCSGM
CDK1P06493humanMAPTP10636-8T153DGKtKIAtPRGAAPP
CDK1P06493humanRANBP2P49792S2280sALsPsKsPAkLNQs
CDK1P06493humanPHLPP1O60346S412PLPQtAssPQPQQKA
CDK1P06493humanCDC27P30260T430INDsLEItkLDssII
CDK1P06493humanSREBF1P36956S439AGsPFQSsPLSLGSR
CDK1P06493humanAPPP05067T743VEVDAAVtPEERHLSAPP_amyloid
CDK1P06493humanYAP1P46937T119AGtAGALtPQHVRAH
CDK1P06493humanPDCD1Q15116S261PSGMGTSsPARRGSA
CDK1P06493humanNUSAP1Q9BXS6T338GNsAAVItPFKLttENUSAP
CDK1P06493humanSRRM2Q9UQ35T866QANEQsVtPQRRsCF
CDK1P06493humanRB1P06400T252PINGsPRtPRRGQNR
CDK1P06493humanTEX14Q8IWB6T727SNLNNMSttEEYLIS
CDK1P06493humanBUB1BO60566S670TLsIkkLsPIIEDsR
CDK1P06493humanSTMN1P16949S38sVPEFPLsPPkKkDLStathmin
CDK1P06493humanNAGKQ9UJ70S76RsLGLsLsGGDQEDABcrAD_BadFG
CDK1P06493humanNCAPGQ9BPX3T308LNALFSItPLSELVG
CDK1P06493humanNUP50Q9UKX7S221kVAAEtQsPsLFGst
CDK1P06493humanMAP4P27816T917SAkPssTtPRLSRLA
CDK1P06493humanAKAP12Q02952T618AsFkkMVtPKKRVRRWSK
CDK1P06493humanRANBP2P49792S2246ssssVHAsPLAssPV
CDK1P06493humanNDE1Q9NXR1-1T215ATGsVPstPIAHRGPNUDE_C
CDK1P06493humanCDC23Q9UJX2T565NQGEtPttEVPAPFF
CDK1P06493humanKIFC1Q9BW19S31APsQLPLsGsRLKRR
CDK1P06493humanPIP5K1CO60331S650DERSWVysPLHYSAQ
CDK1P06493humanEFHD2Q96C19S74QGIGEPQsPsRRVFN
CDK1P06493humanNUP98P52948-2S606RDSENLAsPSEYPEN
CDK1P06493humanBORAQ6PGQ7S252SSGQFSSsPIQASAK
CDK1P06493humanSKA3Q8IX90S283sDAEytNsPLVPTFC
CDK1P06493humanCDT1Q9H211S411PAtPPAAsPsALkGV
CDK1P06493humanSQSTM1Q13501T269GGkRsRLtPVsPEss
CDK1P06493humanNUP98P52948-2T536tPTHYKLtPRPATRV
CDK1P06493humanSP1P08047T739sEGSGtAtPSALITT
CDK1P06493humanING1Q9UK53-2S126LGDTAGNsGKAGADR
CDK1P06493humanTTKP33981S281VPVNLLNsPDCDVkt
CDK1P06493humanADD1P35611S12SRAAVVtsPPPtTAP
CDK1P06493humanTRIM32Q13049S328TFREMDMsPEEVVAs
CDK1P06493humanVCPIP1Q96JH7S768tPtkAPysPttskEK
CDK1P06493humanPDPK1O15530T354WENLHQQtPPKLTAY
CDK1P06493humanEIF4EBP1Q13541S83PtIPGVtsPssDEPPeIF_4EBP
CDK1P06493humanLIG3P49916S913EkLAtKssPVKVGEK
CDK1P06493humanRSF1Q96T23S1375LPstNGQsPGkAIEN
CDK1P06493humanBARD1Q99728S148NSIkMWFsPRSkKVR
CDK1P06493humanBCL2L11O43521-2S44QTEPQDRsPAPMSCD
CDK1P06493humanLMNAP02545S390EEErLRLsPsPtsQR
CDK1P06493humanAMPHP49418S276PLPsPTAsPNHTLAP
CDK1P06493humanPPP2CAP67775T304EPHVTRRtPDyFl__
CDK1P06493humanMORC2Q9Y6X9T733PIKLsPAtPsRKRsV
CDK1P06493humanPYCR2Q96C36S304VSTLTPssPGkLLtR
CDK1P06493humanCSNK2A1P68400T360SGISSVPtPsPLGPL
CDK1P06493humanPRC1O43663T481RrGLAPNtPGkARkL
CDK1P06493humanBCL2L1Q07817S62PSWHLADsPAVNGAT
CDK1P06493humanNUMA1Q14980S2087tRSGtRRsPRIATTT
CDK1P06493humanPAICSP22234S27EVyELLDsPGkVLLQSAICAR_synt
CDK1P06493humanNUMA1Q14980T2015SCFPRPMtPRDRHEG
CDK1P06493humanYAP1P46937S128QHVRAHssPAsLQLG
CDK1P06493humanRFC1P35251T506KESKLERtPQkNVQG
CDK1P06493humanOSBP2Q969R2S762ECSKVMHssPssPsSOxysterol_BP
CDK1P06493humanBAG3O95817S284EGsPARsstPLHsPs
CDK1P06493humanERCC6LQ2NKX8T1063VKQFDAstPkNDIsP
CDK1P06493humanBRCA2P51587S3291sPICTFVsPAAQKAF
CDK1P06493humanNDUFV1P49821T383HESCGQCtPCREGVDNADH_4Fe-4S
CDK1P06493humanMPLKIPQ8TAP9T120QGsPrTstPFGsGrVMPLKIP
CDK1P06493humanNDE1Q9NXR1-1T228GPsssLNtPGsFRRGNUDE_C
CDK1P06493humanTEX14Q8IWB6T728NLNNMSttEEYLISK
CDK1P06493humanBIRC5O15392T34FLEGCACtPERMAEABIR
CDK1P06493humanUNGP13051S64EPGtPPssPLsAEQL
CDK1P06493humanSKA3Q8IX90T291PLVPTFCtPGLkIPS
CDK1P06493humanUSP16Q9Y5T5S552DLEVLtssPtRNLNGUCH
CDK1P06493humanBUB1O43683S593CNktLAPsPksPGDF
CDK1P06493humanLIG1P18858S76EEEDEALsPAkGQKP
CDK1P06493humanDNMT1P26358S154AkPEPsPsPRITRkS
CDK1P06493humanMAP3K11Q16584S548GQAWGRQsPRRLEDs
CDK1P06493humanBRCA1P38398S114FAkKENNsPEHLkDE
CDK1P06493humanDCTN6O00399T186KTMKGSStPVKN___
CDK1P06493humanRB1P06400S249AVIPINGsPRtPRRG
CDK1P06493humanIRS2Q9Y4H2S391sVAGsPLsPGPVRAP
CDK1P06493humanHASPINQ8TF76T128RPPQKCStPCGPLRL
CDK1P06493humanFOXK2Q01167S428FAQsAPGsPLssQPV
CDK1P06493humanCDC27P30260T343sGNsREVtPILAQTQ
CDK1P06493humanCHEK1O14757S301IQsNLDFsPVNsAss
CDK1P06493humanPALLDQ8WX93S766SsLPsPMsPTPrQFG
CDK1P06493humanCDC25BP30305-2S307KCQRLFRsPsMPCSVM-inducer_phosp
CDK1P06493humanNCKAP5LQ9HCH0S571RStFRGPsPEPPPsP
CDK1P06493humanPITPNM1O00562S382DFIDAFAsPVEAEGt
CDK1P06493humanMPLKIPQ8TAP9S93YPGSYsrsPAGsQQQ
CDK1P06493humanNUAK1O60285S445TGVLLPssPEAEVPG
CDK1P06493humanHMGA1P17096S36PRkQPPVsPGtALVG
CDK1P06493humanNDE1Q9NXR1-1T246stGGtPLtPAARISANUDE_C
CDK1P06493humanCDC27P30260S312PPVIDVPstGAPSKk
CDK1P06493humanRRM2P31350S20DPQQLQLsPLkGLsL
CDK1P06493humanNCLP19338T641EIDGNkVtLDWAkPKRRM_1
CDK1P06493humanOSBP2Q969R2S766VMHssPssPsSDGKQOxysterol_BP
CDK1P06493humanECT2Q9H8V3T444TKSSKSStPVPskQS
CDK1P06493humanNPM1P06748T199VkKsIrDtPAkNAQK
CDK1P06493humanLIG3P49916S210TttGQVtsPVkGAsF
CDK1P06493humanBRCA1P38398S1497EPGVERssPsKCPsL
CDK1P06493humanRAB5BP61020S123kELQRQAsPsIVIALRas
CDK1P06493humanLDHAP00338T248VIkLkGYtsWAIGLSLdh_1_C
CDK1P06493humanNUCKS1Q9H1E3S181LkAtVtPsPVkGkGk
CDK1P06493humanBRCA1P38398S1189QKGELsRsPsPFtHT
CDK1P06493humanTPX2Q9ULW0S738QPLtVPVsPkFsTRF
CDK1P06493humanRAB4AP20338S204AALRQLRsPRRAQAP
CDK1P06493humanNCKAP5LQ9HCH0S767RVDLEPVsPRSCLTk
CDK1P06493humanPHLPP1O60346S450VAPGGLQstPGRSGV
CDK1P06493humanCDCA5Q96FF9S139DARDLEMsKKVRRsySororin
CDK1P06493humanREPS2Q8NFH8S463RPRsRsyssTsIEEA
CDK1P06493humanRIT1Q92963S209SVWKRLKsPFRKkKD
CDK1P06493humanRPS3P23396T221kDEILPttPIsEQkG
CDK1P06493humanPHLPP1O60346S324sPAPsDssPGEPFVG
CDK1P06493humanSPAG5Q96R06S249PSSVLWLsPSTALAA
CDK1P06493humanCDC27P30260S435EItkLDssIIsEGkI
CDK1P06493humanACSL4O60488S447LSGGAPLsPQTHRFMAMP-binding
CDK1P06493humanFERMT2Q96AC1S181GsGsIyssPGLyskT
CDK1P06493humanMASTLQ96GX5T194NMMDILTtPSMAkPRPkinase
CDK1P06493humanPDIA3P30101S456GFPtIyFsPANkKLNThioredoxin
CDK1P06493humanPIK3C3Q8NEB9T159DGSEPTktPGRtssTPI3K_C2
CDK1P06493humanLMNAP02545S22QAsstPLsPtRItRL
CDK1P06493humanFLNAP21333S1084LQGGsAGsPArFtIDFilamin
CDK1P06493humanRUNX1Q01196-8S303VHPAtPIsPGRASGM
CDK1P06493humanKIF20BQ96Q89T1644VKHPGCttPVtVKIP
CDK1P06493humanKDM5BQ9UGL1S1456FkLERERsYELVRSA
CDK1P06493humanRUNX2Q13950S465MVPGGDRsPSRMLPPRunxI
CDK1P06493humanBCL2P10415S87AAAGPALsPVPPVVH
CDK1P06493humanCDKN1BP46527T187NAGsVEQtPKKPGLR
CDK1P06493humanWWTR1Q9GZV5S105tGAGAAGsPAQQHAH
CDK1P06493humanTOP2AP11388S1361sPPKTKtsPKLsNkE
CDK1P06493humanRAD9AQ99638S328VLPsIsLsPGPQPPK
CDK1P06493humanRANBP2P49792T2153LLDIPLQtPHkLVDt
CDK1P06493humanFERMT2Q96AC1S186yssPGLyskTMTPty
CDK1P06493humanWEE1P30291S123EEGFGsSsPVKsPAA
CDK1P06493humanMCL1Q07820T92EVPDVTAtPARLLFF
CDK1P06493humanCDCA5Q96FF9S33LRRsQRKsGsELPsI
CDK1P06493humanBARD1Q99728S251sQPSVISsPQINGEI
CDK1P06493humanFLNAP21333S1533GDEEVPRsPFKVkVLFilamin
CDK1P06493humanSP1P08047T723GVALsVGtLPLDsGA
CDK1P06493humanVGLL4Q14135-4S58RTGPPPIsPSKRKFSVGLL4
CDK1P06493humanPHLPP1O60346S336FVGGPVssPRAPRPV
CDK1P06493humanPRDX1Q06830T90CHLAWVNtPkkQGGLAhpC-TSA
CDK1P06493humanRAD9AQ99638S277SHsQDLGsPERHQPV
CDK1P06493humanNCKAP5LQ9HCH0S451AQGPLLPsPARGLKF
CDK1P06493humanPTPN1P18031S386LrGAQAAsPAKGEPs
CDK1P06493humanSPAG5Q96R06S135KTIVLVPsPLGQQQD
CDK1P06493humanPDS5BQ9NTI5T1370AIEstQstPQKGRGR
CDK1P06493humanMAPTP10636-8S202sGyssPGsPGtPGsR
CDK1P06493humanECT2Q9H8V3T373VsMLsLNtPNsNRKR
CDK1P06493humanKPNA2P52292T9stNENANtPAARLHR
CDK1P06493humanSTIM1Q13586S668IGEEtDssPGRKKFP
CDK1P06493humanPKMP14618S37MCRLDIDsPPItARN
CDK1P06493humanUHRF1Q96T88S639QQEGGFAsPRTGkGk
CDK1P06493humanATG13O75143S224DRPYPSSsPMHPCNY
CDK1P06493humanEPN1Q9Y6I3S382FSDPWGGsPAKPSTN
CDK1P06493humanDENRO43583T69PNEFAKLtVENsPKQ
CDK1P06493humanZMYM3Q14202T826PPPPPPAtPRKNKAA
CDK1P06493humanFERMT2Q96AC1S175GPLItPGsGsIyssP
CDK1P06493humanCDKN1AP38936S130sGEQAEGsPGGPGDs
CDK1P06493humanEML3Q32P44T881GAGPAPAtPsRtPsL
CDK1P06493humanANAPC1Q9H1A4S373VQRFNIssHNQsPkR
CDK1P06493humanTPRP12270S2073QAPRAPQsPRRPPHP
CDK1P06493humanTOP2BQ02880S1424DKDEytFsPGKsKAt
CDK1P06493humanNDEL1Q9GZM8T245GFGtsPLtPSARISANUDE_C
CDK1P06493humanOGFRQ9NZT2S378EDRPEPLsPKEsKKR
CDK1P06493humanRECQL4O94761S251EVSIRVGsPQPSSSG
CDK1P06493humanRGPD3A6NKT7S1276HAsPLAssPVRKNLF
CDK1P06493humanRAD9AQ99638S336PGPQPPKsPGPHsEE
CDK1P06493humanPHF8Q9UPP1S120GKPVkTGsPtFVREL
CDK1P06493humanANAPC1Q9H1A4S547PLsKLLGsLDEVVLL
CDK1P06493humanANAPC1Q9H1A4S688FDFEGsLsPVIAPkkApc1_MidN
CDK1P06493humanECT2Q9H8V3T846RAFsFsktPKRALRR
CDK1P06493humanDDHD1Q8NEL9S11PGrGsPRsPEHNGRG
CDK1P06493humanEZH2Q15910T487APAEDVDtPPRKKKR
CDK1P06493humanSIRT3Q9NTG7T150MVGAGIStPSGIPDFSIR2
CDK1P06493humanLRRK1Q38SD2T1427GALGVEGtPGyQAPEPkinase
CDK1P06493humanRNMTO43148T77SSSCGKDtPsKKRKL
CDK1P06493humanNUP98P52948-2T529AAQKALttPTHYKLt
CDK1P06493humanRPS6KB1P23443S394TRQtPVDsPDDStLSPkinase_C
CDK1P06493humanNOLC1Q14978T610IkLQtPNtFPKRKKG
CDK1P06493humanAHNAKQ09666S5763EAEAEAssPkGKFsL
CDK1P06493humanPSMA5P28066S16DrGVNtFsPEGrLFQProteasome_A_N
CDK1P06493humanCDC27P30260T205PEtVLtEtPQDtIEL
CDK1P06493humanPOLR1GO15446S285PLEDtVLsPtKKRKR
CDK1P06493humanNDE1Q9NXR1-1T243LDDstGGtPLtPAARNUDE_C
CDK1P06493humanNDUFV3P56181S105QPssGREsPRH____
CDK1P06493humanSGO1Q5FBB7T346LEEGVHLtPFRQKVS
CDK1P06493humanPHF8Q9UPP1S69CQDWFHGsCVGVEEEPHD
CDK1P06493humanDTLQ9NZJ0T464DLPLPsNtPTFSIKt
CDK1P06493humanCDC25CP30307S214sRsGLyRsPsMPENLM-inducer_phosp
CDK1P06493humanEEF2KO00418S359GtEEKCGsPQVRtLs
CDK1P06493humanNUSAP1Q9BXS6T300HKRsLtKtPARksAHNUSAP
CDK1P06493humanDEPDC1Q5TB30S110LFRFPAtsPLkTLPR
CDK1P06493humanSKA3Q8IX90T203sLVkVLKtPKCALkM
CDK1P06493humanPIK3C2AO00443S259kVSNLQVsPkSEDIS
CDK1P06493humanKIFC1Q9BW19S26RPLIkAPsQLPLsGs
CDK1P06493humanSSR1P43307S268LNQINkAsPRRLPRKTRAP_alpha
CDK1P06493humanHIF1AQ16665S668DTQSRTAsPNRAGkG
CDK1P06493humanLMNB1P20700S23GGPttPLsPtRLsRL
CDK1P06493humanE2F1Q01094S332TDSATIVsPPPSsPP
CDK1P06493humanTEX14Q8IWB6T618EEASSPStGQPSLCS
CDK1P06493humanXIAPP98170S40FANFPSGsPVSAstLBIR
CDK1P06493humanVGLL4Q14135-4S155ASRPAGLsPTLtPGEVGLL4
CDK1P06493humanBUB1BO60566S1043WkVGkLtsPGALLFQ
CDK1P06493humanBARD1Q99728T299KSRNEVVtPEKVCkN
CDK1P06493humanDDHD1Q8NEL9S727TIPsPVtsPVLSRRHDDHD
CDK1P06493humanCDCA5Q96FF9S209DMtLPGIsPPPEKQKSororin
CDK1P06493humanSLX4Q8IY92T1544QKPEGLEtPKGANRK
CDK1P06493humanMAPK6Q16659T698kSIQATLtPSAMkss
CDK1P06493humanUBE2AP49459S120LDEPNPNsPANSQAAUQ_con
CDK1P06493humanRECQL5O94762S727sAHYGGPsPEKKAKSRecQ5
CDK1P06493humanFERMT1Q9BQL6S174LEssPTAsGsSVsPG
CDK1P06493humanFOXM1Q08050-2T596ETLPISStPSKSVLP
CDK1P06493humanWWTR1Q9GZV5T326GCySVPTtPEDFLSN
CDK1P06493humanCDC25CP30307T48VCPDVPRtPVGkFLG
CDK1P06493humanNCOA3Q9Y6Q9S867sPVsVGssPPVKNIS
CDK1P06493humanCSNK2BP67870S209QAAsNFksPVktIR_
CDK1P06493humanWEE1P30291S139yFLGSsFsPVRCGGP
CDK1P06493humanTFPTP0C1Z6S180PAPPEPGsPAPGEGP
CDK1P06493humanBUB1O43683T609sAAQLAstPFHkLPV
CDK1P06493humanESPL1Q14674S1126IAPStNSsPVLKTKP
CDK1P06493humanTSC1Q92574T417SLPQATVtPPRKEERHamartin
CDK1P06493humanFEN1P39748S187MDCLTFGsPVLMrHLXPG_I
CDK1P06493humanKIF20AO95235T198LQGQLHPtPDLKPLLKinesin
CDK1P06493humanBAG3O95817T285GsPARsstPLHsPsP
CDK1P06493humanATAD5Q96QE3S653TVPFDsEsPIRMKFt
CDK1P06493humanCSNK2A1P68400S370PLGPLAGsPVIAAAN
CDK1P06493humanSLX4Q8IY92T1571PQYSIMEtPVLkKEL
CDK1P06493humanPKN1Q16512S562LGtDsDssPQkSSRD
CDK1P06493humanDDX3XO00571T204LTRyTRPtPVQkHAIDEAD
CDK1P06493humanERCC6Q03468T1031GTGSDVQtPKCHLKR
CDK1P06493humanU2AF2P26368S79EHGGLIRsPRHEKKK
CDK1P06493humanUBXN2BQ14CS0T59TVFksPRtPPQRFys
CDK1P06493humanPHLPP1O60346S317GGWsRRAsPAPsDss
CDK1P06493humanNCAPGQ9BPX3T931KNKEVyMtPLrGVkA
CDK1P06493humanLBRQ14739S71KGGsTsSsPSRRRGS
CDK1P06493humanCDC27P30260S222LNLEssNsKYSLNTD
CDK1P06493humanEIF4EBP1Q13541T70rNsPVtktPPRDLPteIF_4EBP
CDK1P06493humanEPB41P11171-2S679DKRLSTHsPFRTLNISAB
CDK1P06493humanDISC1Q9NRI5S713QLQEARGsLSVEDER
CDK1P06493humanNSFL1CQ9UNZ2S140AVERVTksPGETSkP
CDK1P06493humanMAP2K1Q02750T286VEGdAAEtPPRPRtPPkinase
CDK1P06493humanNDE1Q9NXR1-1T191QKQEKPRtPMPSSVENUDE_C
CDK1P06493humanFANCGO15287S387PRFsPPPsPPGPCMP
CDK1P06493humanDAB2IPQ5VWQ8-2T531DVHTALStPGSGQLPDUF3498
CDK1P06493humanDLG1Q12959S158FVsHsHIsPIKPTEAMAGUK_N_PEST
CDK1P06493humanNCKAP5LQ9HCH0S577PsPEPPPsPLQVPTY
CDK1P06493humanKIF20AO95235T857LRNLLPRtPtCQsst
CDK1P06493humanSKA3Q8IX90T217MDDFECVtPKLEHFG
CDK1P06493humanPOLR2AP24928S1934sPtysPtsPKGSTYs
CDK1P06493humanRPA2P15927S33GFGsPAPsQAEkkSR
CDK1P06493humanPKN1Q16512S916TGEAPtLsPPRDARPPkinase_C
CDK1P06493humanSETQ01105S7_MAPKRQsPLPPQKK
CDK1P06493humanANAPC4Q9UJX5S779kEEVLsEsEAENQQA
CDK1P06493humanCEP55Q53EZ4S425NREKVAAsPksPtAA
CDK1P06493humanTERF1P54274T344KKERRVGtPQsTKKK
CDK1P06493humanPRPS1P60891S103RQDKKDKsRAPISAKPribosyltran_N
CDK1P06493humanBLMP54132T766IIKLLYVtPEkICAsDEAD
CDK1P06493humanGAPVD1Q14C86S950APHsssssPsKDssR
CDK1P06493humanNPM1P06748S70EAMNyEGsPIkVtLANucleoplasmin
CDK1P06493humanNEDD1Q8NHV4S460STSVLHSsPLNVFMG
CDK1P06493humanGJA1P17302S262sPAkDCGsQkyAyFN
CDK1P06493humanNME2P22392T94GrVMLGEtNPADskPNDK
CDK1P06493humanWACQ9BTA9T482ssQPKVStPVVkQGP
CDK1P06493humanUBAP2LQ14157S454AAPPPPssPLPsKst
CDK1P06493humanRAB11FIP3O75154S102GPRGQLAsPDAPGPG
CDK1P06493humanHJURPQ8NCD3S448LHREyCLsPRNQPRRHJURP_C
CDK1P06493humanCDCA5Q96FF9T48LPEIWPKtPsAAAVR
CDK1P06493humanNME1P15531T94GrVMLGEtNPADskPNDK
CDK1P06493humanANAPC1Q9H1A4T291kFsEQGGtPQNVATS
CDK1P06493humanCASP8Q14790S387yLEMDLSsPQTRYIPPeptidase_C14
CDK1P06493humanSUN1O94901-9S333HTAAHSQsPRLPGRAMRP
CDK1P06493humanTFCP2L1Q9NZI6T177HCISTEFtPRKHGGECP2
CDK1P06493humanFERMT2Q96AC1S177LItPGsGsIyssPGL
CDK1P06493humanDUTP33316S99GPEtPAIsPSKRARP
CDK1P06493humanEGFRP00533S1026PQQGFFssPSTsRtP
CDK1P06493humanMARK2Q7KZI7S619PyGVtPAsPsGHsQG
CDK1P06493humanPHLPP1O60346S425KAPRAIDsPGGAVRE
CDK1P06493humanRPA2P15927S23GAGGYtQsPGGFGsP
CDK1P06493humanID2Q02363S5___MKAFsPVRSVRk
CDK1P06493humanPITPNM1O00562T287SAASNTGtPDGPEAP
CDK1P06493humanPEX14O75381S232NRRQFPPsPsAPKIP
CDK1P06493humanNCOA3Q9Y6Q9S728VVkQEQLsPKKKENNDUF4927
CDK1P06493humanNCKAP5LQ9HCH0S470PTSEKsPsPGGPQLs
CDK1P06493humanDNM1LO00429S616PIPIMPAsPQKGHAV
CDK1P06493humanRCC1P18754S11KRIAKRRsPPADAIP
CDK1P06493humanWWTR1Q9GZV5S90QHVRsHssPAsLQLG
CDK1P06493humanRECQL4O94761S89LNRAATKsPQStPGRDrc1-Sld2
CDK1P06493humanEIF2AK2P19525S456KGtLRyMsPEQISSQPkinase
CDK1P06493humanNINLQ9Y2I6S185WDSEDFGsPQKSCsP
CDK1P06493humanHMGA1P17096T53kEPsEVPtPkRPrGr
CDK1P06493humanBAG3O95817S289RsstPLHsPsPIRVH
CDK1P06493humanCDC7O00311T376QVAPRAGtPGFRAPEPkinase
CDK1P06493humanCDCA5Q96FF9S83PRRsPRIsFFLEKEN
CDK1P06493humanTPP1O14773T201VGLHLGVtPSVIRKR
CDK1P06493humanELAVL1Q15717S202LLsQLyHsPArrFGG
CDK1P06493humanKDM5BQ9UGL1S1328NRTSYLHsPFSTGRS
CDK1P06493humanSASS6Q6UVJ0S510NTIRsGIsPNLNVVD
CDK1P06493humanBAG3O95817S291stPLHsPsPIRVHTV
CDK1P06493humanCDC27P30260T329ARIGQTGtkSVFsQs
CDK1P06493humanBCL2P10415T69SRDPVARtsPLQtPA
CDK1P06493humanABI1Q8IZP0S216VPNDyMtsPARLGsQ
CDK1P06493humanINCENPQ9NQS7T59EPELMPKtPSQKNRR
CDK1P06493humanRANBP2P49792S2276FsFksALsPsKsPAk
CDK1P06493humanOSBP2Q969R2S768HssPssPsSDGKQKTOxysterol_BP
CDK1P06493humanTOP1P11387S394SKDAkVPsPPPGHkWTopoisom_I_N
CDK1P06493humanEIF4G2P78344T508AQPPrtQtPPLGQtP
CDK1P06493humanTOP2AP11388S1354DFVPsDAsPPKTKts
CDK1P06493humanRB1P06400T373VNVIPPHtPVRTVMNRB_A
CDK1P06493humanSEPTIN9Q9UHD8-2T24EVETPNStPPRRVQT
CDK1P06493humanCKAP2Q8WWK9T623FkELkFLtPVRRsRRCKAP2_C
CDK1P06493humanRPS6KB1P23443S434sFEPKIRsPRRFIGs
CDK1P06493humanCEP55Q53EZ4S428KVAAsPksPtAALNE
CDK1P06493humanANAPC1Q9H1A4S355AALsrAHsPALGVHs
CDK1P06493humanITPR1Q14643S421VMLKIGtsPVkEDkEMIR
CDK1P06493humanBUB1BO60566S543LsEkKNksPPADPPR
CDK1P06493humanSOD2P04179S106SIFWTNLsPNGGGEPSod_Fe_N
CDK1P06493humanCDCA5Q96FF9T159LGsAStstPGRRsCFSororin
CDK1P06493humanWACQ9BTA9T471PIkPLIstPPVssQP
CDK1P06493humanKAT5Q92993S90LPGsRPGsPEREVPA
CDK1P06493humanKAT7O95251T85tRsQQQPtPVtPkKY
CDK1P06493humanRCC1P18754S387GQDEDAWsPVEMMGKRCC1
CDK1P06493humanCHMP7Q8WUX9S3_____MWsPEREAEA
CDK1P06493humanTERTO14746T249AAPEPERtPVGQGSW
CDK1P06493humanMPLKIPQ8TAP9S104sQQQFGYsPGQQQtHMPLKIP
CDK1P06493humanANAPC1Q9H1A4S555LDEVVLLsPVPELRD
CDK1P06493humanCDC16Q13042T581TAEETGLtPLETsRK
CDK1P06493humanBARD1Q99728S288PLAEQIEsPDTKSRN
CDK1P06493humanHMGN5P82970T31sAMLVPVtPEVkPKRHMG14_17
CDK1P06493humanKIFC1Q9BW19S6__MDPQRsPLLEVKG
CDK1P06493humanRPTORQ8N122T706ttEGGsLtPVRDsPC
CDK1P06493humanDLGAP5Q15398T639GPsQRLGtPKsVNkA
CDK1P06493humanPI4KBQ9UBF8S266PAPDtGLsPsKRTHQ
CDK1P06493humanTRIM32Q13049S339VVAsPRAsPAkQRGP
CDK1P06493humanRGCCQ9H4X1T111ALLsAtVtPQKAKLGRGCC
CDK1P06493humanCDC27P30260S434LEItkLDssIIsEGk
CDK1P06493humanCLASP2O75122S1013HSMPtHssPRsRDyN
CDK1P06493humanBORAQ6PGQ7S41LHEQtLAsPSVFkSTBORA_N
CDK1P06493humanMAPTP10636-8T212tPGsRsRtPsLPtPP
CDK1P06493humanSIRT1Q96EB6T530YLSELPPtPLHVsED
CDK1P06493humanYAP1P46937T143AVsPGtLtPtGVVsG
CDK1P06493humanSUN1O94901-9S48KLDPVFDsPRMSRRS
CDK1P06493humanCDC25BP30305S50PVRAAASsPVttLtQ
CDK1P06493humanARP10275S83QQQQQETsPRQQQQQAndrogen_recep
CDK1P06493humanDLGAP5Q15398T329TYQVtPMtPRsANAFGKAP
CDK1P06493humanATRQ13535S428SSNSDGIsPKRRRLs
CDK1P06493humanTPX2Q9ULW0T72NLQQAIVtPLkPVDN
CDK1P06493humanBRCA1P38398S1191GELsRsPsPFtHTHL
CDK1P06493humanCCNB1P14635S128LVDTAsPsPMETsGC
CDK1P06493humanPMLP29590S518PsTSkAVsPPHLDGPDUF3583
CDK1P06493humanFMNL2Q96PY5S1016MEQQDPKsPsHKSKR
CDK1P06493humanVHLP40337S80QVIFCNrsPRVVLPVVHL
CDK1P06493humanMKI67P46013T1943GskRRPQtPKEKAkAKI67R
CDK1P06493humanDCTN1Q14203S212GAVPPLPsPsKEEEG
CDK1P06493humanKAT7O95251T88QQQPtPVtPkKYPLR
CDK1P06493humanFOXM1Q08050T600EVGGPFKtPIkETLP
CDK1P06493humanOSBP2Q969R2S763CSKVMHssPssPsSDOxysterol_BP
CDK1P06493humanRFC1P35251S518VQGkRKIsPSKKESE
CDK1P06493humanCDCA5Q96FF9T151RsysRLEtLGsAStsSororin
CDK1P06493humanKIF4AO95239T1161FFNPVCAtPNsKILK
CDK1P06493humanPTPN2P17706-2S304LSPAFDHsPNKIMTE
CDK1P06493humanCDCA5Q96FF9S164tstPGRRsCFGFEGLSororin
CDK1P06493humanTOB2Q14106S254PAPQSQLsPNAKEFVPAM2
CDK1P06493humanTIAM1Q13009S1466SDAVsASsPEKESQQ
CDK1P06493humanSAMHD1Q9Y3Z3T592DVIAPLItPQkkEWN
CDK1P06493humanSUPT5HO00267S666VGGFAPMsPrISsPM
CDK1P06493humanCREB1P16220S257PGVVMAssPALPTQP
CDK1P06493humanYAP1P46937S289PPPLAPQsPQGGVMG
CDK1P06493humanMAPK6Q16659S705tPSAMkssPQIPHQT
CDK1P06493humanPBKQ96KB5T9EGIsNFktPskLsEk
CDK1P06493humanE2F1Q01094S337IVsPPPSsPPSSLTT
CDK1P06493humanCGASQ8N884S305MKRkRGGsPAVTLLIMab-21
CDK1P06493humanRAD9AQ99638T292PQLQAHStPHPDDFA
CDK1P06493humanBCL2P10415T56FSSQPGHtPHPAASR
CDK1P06493humanNHERF1O14745S302EELNsQDsPPKQDSTEBP50_C
CDK1P06493humanCANXP27824S583EDEILNRsPRNRKPR
CDK1P06493humanNEDD1Q8NHV4T550PPINGsstPNPKIAs
CDK1P06493humanPKN1Q16512S533AtGtGTFsPGAsPGs
CDK1P06493humanUSP14P54578T235sssAsAAtPskkKSLUCH
CDK1P06493humanGATA2P23769T176HLFGFPPtPPKEVsP
CDK1P06493humanXPO1O14980S391sPFsTsAsPLLsGsQ
CDK1P06493humanTMPOP42166S424FQETEFLsPPRkVPR
CDK1P06493humanLIMD1Q9UGP4S424VLLDsPssPRVrLPC
CDK1P06493humanNME1P15531S120GRNIIhGsDsVEsAENDK
CDK1P06493humanSCML2Q9UQR0S267AsQHsMQsPQKTTLI
CDK1P06493humanWWC1Q8IX03S542sPRSsLSsPSPPCsP
CDK1P06493humanNDUFA12Q9UI09T142QEWIPPStPYK____
CDK1P06493humanDNM2P50570T766sAssHsPtPQRRPVS
CDK1P06493humanMAP7Q14244S209ssAtLLNsPDRARRL
CDK1P06493humanRANBP2P49792S2251HAsPLAssPVRkNLF
CDK1P06493humanNPM1P06748T219kDskPsstPRskGQE
CDK1P06493humanSKA3Q8IX90T360ENLLRtPtPPEVTkI
CDK1P06493humanCDCA5Q96FF9T115VPAtPtStPVPNPEASororin
CDK1P06493humanPTTG2Q9NZH5S165LFQLGPPsPVKMPSPSecurin
CDK1P06493humanCDCA5Q96FF9S75VEVPAVQsPRRsPRI
CDK1P06493humanNUP98P52948-2T653IAKPIPQtPESAGNK
CDK1P06493humanRB1P06400S807PGGNIyIsPLksPykRb_C
CDK1P06493humanSCML2Q9UQR0S590sPLVGDIsPKssPHE
CDK1P06493humanUSP24Q9UPU5S2047QRVSDQNsPVLPKKS
CDK1P06493humanWACQ9BTA9T457YVsPRIstPQtNTVP
CDK1P06493humanCCNE1P24864S399GLLtPPQsGKKQSSG
CDK1P06493humanNUP98P52948-2S595LNNsNLFsPVNRDSE
CDK1P06493humanSTK3Q13188S385tMKRNAtsPQVQRPs
CDK1P06493humanUSP24Q9UPU5S1616NsHsPAGsAAIsQQD
CDK1P06493humanMEF2CQ06413S396NIkSEPVsPPRDRTT
CDK1P06493humanCDC14AQ9UNH5S549SNGGNLNsPPGPHSA
CDK1P06493humanNCLP19338T707HKPQGKKtKFE____
CDK1P06493humanMCM7P33993S121RDPGMVRsPQNQYPAMCM_N
CDK1P06493humanCREB1P16220S256APGVVMAssPALPTQ
CDK1P06493humanPPP6R2O75170S771ESGPRCSsPVDTECS
CDK1P06493humanGIGYF2Q6Y7W6S30sItsPPLsPALPkYk
CDK1P06493humanCDC27P30260T446EGkIStItPQIQAFN
CDK1P06493humanTOP1P11387S112EKENGFssPPQIkDE
CDK1P06493humanFLNAP21333S1459kCsGPGLsPGMVRANFilamin
CDK1P06493humanFERMT2Q96AC1S180PGsGsIyssPGLysk
CDK1P06493humanFOXM1Q08050T620SkSVLPRtPEsWRLt
CDK1P06493humanRUNX1Q01196-8S293QYLGSIAsPSVHPAt
CDK1P06493humanPHLPP1O60346S323AsPAPsDssPGEPFV
CDK1P06493humanMAPTP10636-8T205ssPGsPGtPGsRsRt
CDK1P06493humanCDCA8Q53HL2S219YNIsGNGsPLADskEBorealin
CDK1P06493humanMAPK3P27361-3S343PTDEVGQsPAAVGLG
CDK1P06493humanMAP4P27816T901MPsRPsttPFIDKKP
CDK1P06493humanTOP2AP11388S1393GsVPLsssPPAtHFP
CDK1P06493humanNPM1P06748T237kQEKtPKtPkGPssV
CDK1P06493humanANAPC1Q9H1A4T701kkARPsEtGsDDDWEApc1_MidN
CDK1P06493humanSQSTM1Q13501S272RsRLtPVsPEssstE
CDK1P06493humanPHLPP1O60346T451APGGLQstPGRSGVT
CDK1P06493humanWWC1Q8IX03S931IIRsKtFsPGPQSQy
CDK1P06493humanANAPC1Q9H1A4T530NtMPRPstPLDGVst
CDK1P06493humanHMGA1P17096-2T42kEPsEVPtPkrPrGr
CDK1P06493humanBORAQ6PGQ7S112TkDVIVPsPWTDHEGBORA_N
CDK1P06493humanKIF11P52732T926LDIPtGttPQRksyLMicrotub_bind
CDK1P06493humanLMNAP02545S392ErLRLsPsPtsQRsR
CDK1P06493humanHJURPQ8NCD3S412RTLkWLIsPVkIVSRHJURP_C
CDK1P06493humanTP53BP1Q12888T1609LGPyEAVtPLtkAAD
CDK1P06493humanCDT1Q9H211T406LPAtPPAtPPAAsPs
CDK1P06493humanPPP1R13LQ8WUF5S84EPFGsrGsPRkAAtD
CDK1P06493humanRB1P06400S811IyIsPLksPykIsEGRb_C
CDK1P06493humanEZH2Q15910T345LtAERIKtPPkRPGG
CDK1P06493humanNCAPGQ9BPX3T332LIPVETLtPEIALYW
CDK1P06493humanEP300Q09472S2039GLGQVGIsPLKPGTVCreb_binding
CDK1P06493humanHNRNPKP61978S216ILDLIsEsPIkGRAQ
CDK1P06493humanLATS1O95835S613EKKQITtsPItVRKN
CDK1P06493humanMAPTP10636-8S235VVRtPPKsPssAKsR
CDK1P06493humanKRT8P05787S432sAyGGLtsPGLsysL
CDK1P06493humanADD1P35611S355kYKAKsRsPGsPVGE
CDK1P06493humanZC3H11AO75152T321PETNIDKtPKKAQVs
CDK1P06493humanKIF20AO95235S21sDDDVVVsPMFESTA
CDK1P06493humanNDUFB6O95139S55NkFLENksPWRKMVHNDUF_B6
CDK1P06493humanEP300Q09472S1038STSATQssPAPGQsk
CDK1P06493humanTOP2AP11388S1213QMAEVLPsPRGQRVI
CDK1P06493humanCLASP2O75122S541REssRDTsPVRSFQP
CDK1P06493humanYAP1P46937S138sLQLGAVsPGtLtPt
CDK1P06493humanSIRT1Q96EB6S540HVsEDsssPERtsPP
CDK1P06493humanSIRT2Q8IXJ6S368PNPsTsAsPKKsPPP
CDK1P06493humanNANOGQ9H9S0S71DsPDsStsPKGKQPt
CDK1P06493humanSLX4Q8IY92T1561LPPKVPItPMPQYSI
CDK1P06493humanNHERF1O14745S280LAEAALEsPRPALVREBP50_C
CDK1P06493humanEEF1DP29692-2S499APQTQHVsPMRQVEP
CDK1P06493humanBORAQ6PGQ7S137CTNINsDsPVGKkLTBORA_N
CDK1P06493humanCDCA5Q96FF9S79AVQsPRRsPRIsFFL
CDK1P06493humanTP53P04637S315LPNNtsssPQPkkkP
CDK1P06493humanMAP4P27816T892VPSRVKAtPMPsRPs
CDK1P06493humanCDC27P30260S426TQPNINDsLEItkLD
CDK1P06493humanWACQ9BTA9T244AETHSSStPVQHPIK
CDK1P06493humanNEK9Q8TD19T210SEYsMAEtLVGtPYYPkinase
CDK1P06493humanMAP4P27816S787KAPEkRAsPsKPAsA
CDK1P06493humanAPLP2Q06481T736VEVDPMLtPEERHLNAPP_amyloid
CDK1P06493humanPALLDQ8WX93S641PtPAVLLsPTKEPPP
CDK1P06493humanH1-4P10412T18APAPAEktPVkKKAR
CDK1P06493humanMAN1A1P33908S12GLLPLFSsPAGGVLG
CDK1P06493humanVIMP08670S56srsLyAssPGGVyAtFilament_head
CDK1P06493humanARP10275S516VSRVPYPsPTCVkSE
CDK1P06493humanAKT1P31749T308kDGAtMKtFCGtPEyPkinase
CDK1P06493humanNANOGQ9H9S0S65MDLLIQDsPDsStsP
CDK1P06493humanFLNAP21333S1436GGHQVPGsPFKVPVHFilamin
CDK1P06493humanAKAP12Q02952T767EsFkRLVtPRKksKSWSK


check button Biological Network Integration of This Kinase and Substrates
(GeneMANIA website)

check button Enriched GO biological processes of the phosphorylation target genes of the kinase
KinaseGOIDGO termP.adjust
CDK1IDDescription0.00e+00
CDK1GO:0044772mitotic cell cycle phase transition1.74e-43
CDK1GO:0007059chromosome segregation2.49e-39
CDK1GO:0048285organelle fission1.43e-38
CDK1GO:0000280nuclear division1.67e-38
CDK1GO:0140014mitotic nuclear division8.47e-38
CDK1GO:1901987regulation of cell cycle phase transition1.09e-36
CDK1GO:1901990regulation of mitotic cell cycle phase transition5.29e-36
CDK1GO:0098813nuclear chromosome segregation1.94e-30
CDK1GO:0045787positive regulation of cell cycle4.75e-30
CDK1GO:0000819sister chromatid segregation1.69e-29
CDK1GO:0090068positive regulation of cell cycle process8.67e-29
CDK1GO:0000070mitotic sister chromatid segregation3.20e-26
CDK1GO:0050000chromosome localization1.65e-23
CDK1GO:1902850microtubule cytoskeleton organization involved in mitosis1.66e-23
CDK1GO:0010948negative regulation of cell cycle process4.91e-22
CDK1GO:0051303establishment of chromosome localization1.12e-20
CDK1GO:1901988negative regulation of cell cycle phase transition1.22e-20
CDK1GO:0045786negative regulation of cell cycle1.49e-20
CDK1GO:0051656establishment of organelle localization1.62e-20
CDK1GO:0000082G1/S transition of mitotic cell cycle3.20e-20
CDK1GO:0044843cell cycle G1/S phase transition1.22e-19
CDK1GO:0051983regulation of chromosome segregation1.30e-19
CDK1GO:0000075cell cycle checkpoint signaling4.32e-19
CDK1GO:0045931positive regulation of mitotic cell cycle9.55e-19
CDK1GO:1901989positive regulation of cell cycle phase transition1.92e-18
CDK1GO:0006260DNA replication7.03e-18
CDK1GO:1901991negative regulation of mitotic cell cycle phase transition7.83e-18
CDK1GO:0033044regulation of chromosome organization1.05e-17
CDK1GO:0007088regulation of mitotic nuclear division2.07e-17
CDK1GO:0051310metaphase chromosome alignment3.01e-17
CDK1GO:1901992positive regulation of mitotic cell cycle phase transition4.82e-17
CDK1GO:0045930negative regulation of mitotic cell cycle9.54e-17
CDK1GO:0008630intrinsic apoptotic signaling pathway in response to DNA damage1.20e-16
CDK1GO:0007093mitotic cell cycle checkpoint signaling1.58e-16
CDK1GO:0051304chromosome separation1.65e-16
CDK1GO:0007052mitotic spindle organization2.01e-16
CDK1GO:0051783regulation of nuclear division2.99e-16
CDK1GO:1905818regulation of chromosome separation4.11e-16
CDK1GO:0034504protein localization to nucleus1.34e-15
CDK1GO:0007051spindle organization1.34e-15
CDK1GO:0042770signal transduction in response to DNA damage2.07e-15
CDK1GO:0009314response to radiation4.41e-15
CDK1GO:2000045regulation of G1/S transition of mitotic cell cycle8.34e-15
CDK1GO:2001233regulation of apoptotic signaling pathway1.30e-14
CDK1GO:0044839cell cycle G2/M phase transition1.30e-14
CDK1GO:0008608attachment of spindle microtubules to kinetochore2.75e-14
CDK1GO:0033045regulation of sister chromatid segregation3.11e-14
CDK1GO:0006913nucleocytoplasmic transport5.29e-14
CDK1GO:0051169nuclear transport5.29e-14

Top

Related Drugs to CDK1_ASS1


check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

check button Distribution of the number of studies mentioning CDK1-ASS1 and kinase inhibitors the PubMed Abstract (04-01-2024)

Fusion gene - drug pair 1Fusion gene - drug pair 2PMIDPublication dateDOIStudy title

Top

Related Diseases to CDK1_ASS1


check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Related diseases from the literature mentioned this fusion gene and drug.
(PubMed, 04-01-2024)
MeSH IDMeSH term

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource


Top

Clinical Trials of the Found Drugs/Small Molecules


check button Statistics of the Clinical Trials of the Found Kinase Inibitors from clinicaltrials.gov (06-17-2024)

check button Clinical Trials from clinicaltrials.gov (06-17-2024)

Fusion GeneKinase InhibitorNCT IDStudy StatusPhasesDisease# EnrolmentDate