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Kinase Fusion Gene:ITCH_SRC |
Kinase Fusion Protein Summary |
Kinase Fusion gene summary |
Kinase Fusion partner gene information | Kinase Fusion gene name: ITCH_SRC | KinaseFusionDB ID: KFG2914 | FusionGDB2.0 ID: KFG2914 | Hgene | Tgene | Gene symbol | ITCH | SRC | Gene ID | 83737 | 6714 | |
Gene name | itchy E3 ubiquitin protein ligase | SRC proto-oncogene, non-receptor tyrosine kinase | ||||||||||
Synonyms | ADMFD|AIF4|AIP4|NAPP1 | ASV|SRC1|THC6|c-SRC|p60-Src | ||||||||||
Cytomap | 20q11.22 | 20q11.23 | ||||||||||
Type of gene | protein-coding | protein-coding | ||||||||||
Description | E3 ubiquitin-protein ligase Itchy homologHECT-type E3 ubiquitin transferase Itchy homologNFE2-associated polypeptide 1atrophin-1 interacting protein 4itchy E3 ubiquitin protein ligase homolog | proto-oncogene tyrosine-protein kinase Srcproto-oncogene c-Srcprotooncogene SRC, Rous sarcomatyrosine kinase pp60c-srctyrosine-protein kinase SRC-1v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog | ||||||||||
Modification date | 20240403 | 20240411 | ||||||||||
UniProtAcc | Q96J02 | Q9C0H9 | ||||||||||
Ensembl transtripts involved in fusion gene | ENST ids | ENST00000262650, ENST00000374864, ENST00000535650, ENST00000483727, | ENST00000373578, ENST00000358208, ENST00000360723, ENST00000373558, ENST00000373567, ENST00000445403, ENST00000477066, | |||||||||
Context (manual curation of fusion genes in KinaseFusionDB) | PubMed: ITCH [Title/Abstract] AND SRC [Title/Abstract] AND fusion [Title/Abstract] | |||||||||||
Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0) | ITCH(32957276)-SRC(35993607), # samples:2 |
Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
Partner | Gene | GO ID | GO term | PubMed ID |
Hgene | ITCH | GO:0006511 | ubiquitin-dependent protein catabolic process | 15678106 |
Hgene | ITCH | GO:0006513 | protein monoubiquitination | 34927784 |
Hgene | ITCH | GO:0016567 | protein ubiquitination | 17592138|25631046 |
Hgene | ITCH | GO:0035519 | protein K29-linked ubiquitination | 17028573|18628966 |
Hgene | ITCH | GO:0039532 | negative regulation of cytoplasmic pattern recognition receptor signaling pathway | 27736772 |
Hgene | ITCH | GO:0070534 | protein K63-linked ubiquitination | 18718448|19592251 |
Hgene | ITCH | GO:0070936 | protein K48-linked ubiquitination | 19881509|27736772|30328013 |
Tgene | SRC | GO:0018108 | peptidyl-tyrosine phosphorylation | 22732588 |
Tgene | SRC | GO:0018108 | peptidyl-tyrosine phosphorylation | 12051764 |
Tgene | SRC | GO:0034139 | regulation of toll-like receptor 3 signaling pathway | 37158982 |
Tgene | SRC | GO:0035306 | positive regulation of dephosphorylation | 23159740 |
Tgene | SRC | GO:0035556 | intracellular signal transduction | 11606584|15248232 |
Tgene | SRC | GO:0045747 | positive regulation of Notch signaling pathway | 25731159 |
Tgene | SRC | GO:0046777 | protein autophosphorylation | 16441665 |
Tgene | SRC | GO:0060576 | intestinal epithelial cell development | 25731159 |
Tgene | SRC | GO:0070102 | interleukin-6-mediated signaling pathway | 25731159 |
Tgene | SRC | GO:0071902 | positive regulation of protein serine/threonine kinase activity | 19059439 |
Tgene | SRC | GO:1904263 | positive regulation of TORC1 signaling | 35927303 |
Kinase Fusion gene breakpoints across ITCH (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
Kinase Fusion gene breakpoints across SRC (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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Kinase Fusion Gene Sample Information |
Kinase Fusion gene information. |
Kinase Fusion gene information from four resources (ChiTars 5.0, ChimerDB 4.0, COSMIC, and CCLE) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Source | Sample | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp |
ChimerDB4 | TCGA-NH-A50V-01A | ITCH | chr20 | 32957276 | SRC | chr20 | 35993607 |
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Kinase Fusion ORF Analysis |
Kinase Fusion information from ORFfinder translation from full-length transcript sequence from KinaseFusionDB. |
Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | Seq length (transcript) | Seq length (amino acids) |
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Kinase Fusion Amino Acid Sequences |
For individual full-length fusion transcript sequence from KinaseFusionDB, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
>Henst_Tenst_Hgene_Hchr_Hbp_Tgene_Tchr_Tbp_length(fusion AA)_AAseq |
Multiple Sequence Alignment of All Fusion Protein Isoforms |
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Kinase Fusion Protein Functional Features |
Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/:32957276/:35993607) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
Main function of each fusion partner protein. (from UniProt) |
Hgene | Tgene |
ITCH | SRC |
FUNCTION: Acts as an E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates (PubMed:14602072, PubMed:17028573, PubMed:16387660, PubMed:18718448, PubMed:18718449, PubMed:11046148, PubMed:19592251, PubMed:19116316, PubMed:19881509, PubMed:20491914, PubMed:20392206, PubMed:20068034, PubMed:23146885, PubMed:24790097, PubMed:25631046, PubMed:15051726). Catalyzes 'Lys-29'-, 'Lys-48'- and 'Lys-63'-linked ubiquitin conjugation (PubMed:17028573, PubMed:18718448, PubMed:19131965, PubMed:19881509). Involved in the control of inflammatory signaling pathways (PubMed:19131965). Essential component of a ubiquitin-editing protein complex, comprising also TNFAIP3, TAX1BP1 and RNF11, that ensures the transient nature of inflammatory signaling pathways (PubMed:19131965). Promotes the association of the complex after TNF stimulation (PubMed:19131965). Once the complex is formed, TNFAIP3 deubiquitinates 'Lys-63' polyubiquitin chains on RIPK1 and catalyzes the formation of 'Lys-48'-polyubiquitin chains (PubMed:19131965). This leads to RIPK1 proteasomal degradation and consequently termination of the TNF- or LPS-mediated activation of NFKB1 (PubMed:19131965). Ubiquitinates RIPK2 by 'Lys-63'-linked conjugation and influences NOD2-dependent signal transduction pathways (PubMed:19592251). Regulates the transcriptional activity of several transcription factors, and probably plays an important role in the regulation of immune response (PubMed:18718448, PubMed:20491914). Ubiquitinates NFE2 by 'Lys-63' linkages and is implicated in the control of the development of hematopoietic lineages (PubMed:18718448). Mediates JUN ubiquitination and degradation (By similarity). Mediates JUNB ubiquitination and degradation (PubMed:16387660). Critical regulator of type 2 helper T (Th2) cell cytokine production by inducing JUNB ubiquitination and degradation (By similarity). Involved in the negative regulation of MAVS-dependent cellular antiviral responses (PubMed:19881509). Ubiquitinates MAVS through 'Lys-48'-linked conjugation resulting in MAVS proteasomal degradation (PubMed:19881509). Following ligand stimulation, regulates sorting of Wnt receptor FZD4 to the degradative endocytic pathway probably by modulating PI42KA activity (PubMed:23146885). Ubiquitinates PI4K2A and negatively regulates its catalytic activity (PubMed:23146885). Ubiquitinates chemokine receptor CXCR4 and regulates sorting of CXCR4 to the degradative endocytic pathway following ligand stimulation by ubiquitinating endosomal sorting complex required for transport ESCRT-0 components HGS and STAM (PubMed:14602072, PubMed:23146885, PubMed:34927784). Targets DTX1 for lysosomal degradation and controls NOTCH1 degradation, in the absence of ligand, through 'Lys-29'-linked polyubiquitination (PubMed:17028573, PubMed:18628966, PubMed:23886940). Ubiquitinates SNX9 (PubMed:20491914). Ubiquitinates MAP3K7 through 'Lys-48'-linked conjugation (By similarity). Involved in the regulation of apoptosis and reactive oxygen species levels through the ubiquitination and proteasomal degradation of TXNIP (PubMed:20068034). Mediates the antiapoptotic activity of epidermal growth factor through the ubiquitination and proteasomal degradation of p15 BID (PubMed:20392206). Ubiquitinates BRAT1 and this ubiquitination is enhanced in the presence of NDFIP1 (PubMed:25631046). Inhibits the replication of influenza A virus (IAV) via ubiquitination of IAV matrix protein 1 (M1) through 'Lys-48'-linked conjugation resulting in M1 proteasomal degradation (PubMed:30328013). Ubiquitinates NEDD9/HEF1, resulting in proteasomal degradation of NEDD9/HEF1 (PubMed:15051726). {ECO:0000250|UniProtKB:Q8C863, ECO:0000269|PubMed:14602072, ECO:0000269|PubMed:15051726, ECO:0000269|PubMed:16387660, ECO:0000269|PubMed:17028573, ECO:0000269|PubMed:18628966, ECO:0000269|PubMed:18718448, ECO:0000269|PubMed:18718449, ECO:0000269|PubMed:19116316, ECO:0000269|PubMed:19131965, ECO:0000269|PubMed:19592251, ECO:0000269|PubMed:19881509, ECO:0000269|PubMed:20068034, ECO:0000269|PubMed:20392206, ECO:0000269|PubMed:20491914, ECO:0000269|PubMed:23146885, ECO:0000269|PubMed:23886940, ECO:0000269|PubMed:24790097, ECO:0000269|PubMed:25631046, ECO:0000269|PubMed:30328013}. | FUNCTION: Acts as a negative regulator of SRC by activating CSK which inhibits SRC activity and downstream signaling, leading to impaired cell spreading and migration. Regulates dendritic spine morphology. Involved in calcium-dependent exocytosis. May play a role in neurotransmitter release or synapse maintenance. {ECO:0000269|PubMed:14657239, ECO:0000269|PubMed:17525734, ECO:0000269|PubMed:19146815}. |
Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
- Retained domain in the 5'-partner of fusion protein (protein functional feature from UniProt). |
Partner | Hgeneene | Hbp | Tgeneene | Tbp | ENST | BPexon | TotalExon | Protein feature loci | BPloci | TotalLen | Feature | Note |
- Retained domain in the 3'-partner of fusion protein (protein functional feature from UniProt). |
Partner | Hgeneene | Hbp | Tgeneene | Tbp | ENST | BPexon | TotalExon | Protein feature loci | BPloci | TotalLen | Feature | Note |
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Kinase-Substrate Information of ITCH_SRC |
Phosphorylation target of the kinase (phosphosite, 03-17-2024) |
Kinase | Kinase UniProt Acc | Kinase species | Substrate | Substrate UniProt Acc | Substrate phosphorylated residues | Substrate phosphorylated sites (+/-7AA) | Domain |
SRC | P12931 | human | PTEN | P60484 | Y155 | AQEALDFyGEVRTRD | |
SRC | P12931 | human | GJA1 | P17302 | Y265 | kDCGsQkyAyFNGCs | |
SRC | P12931 | human | SPTAN1 | Q13813 | Y1073 | MkQVEELyHsLLELG | |
SRC | P12931 | human | YAP1 | P46937 | Y407 | sGLsMsSySVPRtPD | |
SRC | P12931 | human | TIMP2 | P16035 | Y90 | EKDIEFIyTAPSSAV | TIMP |
SRC | P12931 | human | FLT4 | P35916 | Y830 | PLEEQCEyLSyDASQ | |
SRC | P12931 | human | THRAP3 | Q9Y2W1 | Y344 | AAsGGAAytKRyLEE | THRAP3_BCLAF1 |
SRC | P12931 | human | CDCP1 | Q9H5V8 | Y734 | KDNDsHVyAVIEDTM | |
SRC | P12931 | human | HNF4A | P41235 | Y288 | IDDNEyAyLKAIIFF | Hormone_recep |
SRC | P12931 | human | EYA3 | Q99504 | S138 | SGLIQTPsPSQHSVL | |
SRC | P12931 | human | SHC1 | P29353-3 | Y194 | EEPPDHQyyNDFPGK | |
SRC | P12931 | human | EYA3 | Q99504 | Y426 | YRKVREIyDKHkSNV | |
SRC | P12931 | human | HDAC3 | O15379 | Y331 | PySEyFEyFAPDFTL | |
SRC | P12931 | human | KIF11 | P52732 | Y211 | VHNkDEVyQILEkGA | Kinesin |
SRC | P12931 | human | GBF1 | Q92538 | Y516 | VENPKMPyEMKEMAL | Sec7_N |
SRC | P12931 | human | ATG9A | Q7Z3C6 | Y8 | MAQFDTEyQRLEAsy | |
SRC | P12931 | human | GTF2I | P78347-2 | Y248 | EESEDPDyyQyNIQG | |
SRC | P12931 | human | TRPV1 | Q8NER1 | Y200 | ASYtDSYyKGQTALH | Ank_2 |
SRC | P12931 | human | BCKDK | O14874 | Y246 | RRLCEHkyGNAPRVR | |
SRC | P12931 | human | PLCG2 | P16885 | Y753 | ERDINSLyDVsRMyV | |
SRC | P12931 | human | CDH2 | P19022 | Y884 | SSGGEQDyDyLNDWG | CADH_Y-type_LIR |
SRC | P12931 | human | BDKRB2 | P30411 | Y347 | RKKSWEVyQGVCQKG | |
SRC | P12931 | human | WNK4 | Q96J92 | Y1164 | KKEIEDLySRLGKQP | |
SRC | P12931 | human | GIT1 | Q9Y2X7 | Y284 | EELAMDVyDEVDRRE | GIT_SHD |
SRC | P12931 | human | GAB1 | Q13480 | Y242 | FFQQQMIyDsPPSRA | |
SRC | P12931 | human | AKAP8 | O43823 | Y53 | TTGATySyGPASWEA | |
SRC | P12931 | human | CHN2 | P52757 | Y21 | VSSDAEEyQPPIWKS | |
SRC | P12931 | human | HNRNPK | P61978 | Y234 | PNFyDETyDyGGFTM | |
SRC | P12931 | human | ACLY | P53396 | Y682 | sRtTDGVyEGVAIGG | Ligase_CoA |
SRC | P12931 | human | SFPQ | P23246 | Y691 | GPGtPAGyGrGrEEy | |
SRC | P12931 | human | DVL2 | O14641 | Y18 | VGEtKVIyHLDEEET | DIX |
SRC | P12931 | human | GTF2I | P78347 | Y248 | EESEDPDyyQYNIQA | |
SRC | P12931 | human | HLA-A | P04439 | Y344 | sDRkGGsytQAAssD | MHC_I_C |
SRC | P12931 | human | EPS8 | Q12929 | Y485 | EHssVsEyHPADGyA | |
SRC | P12931 | human | DAPK1 | P53355 | Y490 | HCAAWHGyySVAKAL | Ank_2 |
SRC | P12931 | human | RGS16 | O15492 | Y177 | RFLkSPAyRDLAAQA | RGS |
SRC | P12931 | human | ZC3H4 | Q9UPT8 | Y247 | SRGRGRGyRGRGSRG | |
SRC | P12931 | human | PAG1 | Q9NWQ8 | Y317 | EEEIsAMyssVNKPG | PAG |
SRC | P12931 | human | DDR2 | Q16832 | Y736 | FGMSRNLysGDyyRI | PK_Tyr_Ser-Thr |
SRC | P12931 | human | NR1H4 | Q96RI1 | Y77 | QISSSSYySNLGFYP | |
SRC | P12931 | human | SF3B2 | Q13435 | Y379 | VtEEPEIyEPNFIFF | |
SRC | P12931 | human | BCLAF1 | Q9NYF8 | Y80 | YRGrGrGyyQGGGGr | |
SRC | P12931 | human | PDPK1 | O15530 | Y376 | DEDCyGNyDNLLSQF | |
SRC | P12931 | human | FHOD1 | Q9Y613 | Y99 | REMLEGFyEEISKGR | Formin_GBD_N |
SRC | P12931 | human | SHC1 | P29353-3 | Y272 | ELFDDPSyVNVQNLD | |
SRC | P12931 | human | UGT2B7 | P16662 | Y438 | RVINDPSyKENVMKL | UDPGT |
SRC | P12931 | human | BAIAP2L1 | Q9UHR4 | Y156 | GsRNALkyEHKEIEy | IMD |
SRC | P12931 | human | EYA3 | Q99504 | Y77 | QMySAKPyAHILSVP | |
SRC | P12931 | human | GBF1 | Q92538 | Y1374 | PsPLINQysLTVGLD | |
SRC | P12931 | human | GLRB | P48167 | Y435 | RDFELSNyDCYGkPI | Neur_chan_memb |
SRC | P12931 | human | GRIK2 | Q13002 | Y590 | RFSPYEWyNPHPCNP | Lig_chan |
SRC | P12931 | human | L1CAM | P32004 | Y1176 | kDEtFGEyRSLEsDN | Bravo_FIGEY |
SRC | P12931 | human | HRAS | P01112 | Y64 | DTAGQEEySAMRDQY | Ras |
SRC | P12931 | human | NEDD4 | P46934-4 | Y332 | RRGsLQAyTFEEQPT | |
SRC | P12931 | human | PTPN6 | P29350 | Y564 | sKHkEDVyENLHTkN | |
SRC | P12931 | human | PARP1 | P09874 | Y992 | LYNEYIVyDIAQVNL | PARP |
SRC | P12931 | human | PTK2 | Q05397 | Y925 | DRsNDkVyENVtGLV | Focal_AT |
SRC | P12931 | human | CDC25A | P30304 | Y59 | LQGLGSDyEQPLEVK | |
SRC | P12931 | human | ANXA2 | P07355 | Y24 | HstPPsAyGsVkAyt | |
SRC | P12931 | human | USP2 | O75604 | S207 | ENYGRKGsASQVPSQ | |
SRC | P12931 | human | CD46 | P15529-4 | Y354 | kADGGAEyAtyQtkS | |
SRC | P12931 | human | NOS2 | P35228 | Y1055 | LPGKPKVyVQDILRQ | NAD_binding_1 |
SRC | P12931 | human | TLR3 | O15455 | Y759 | EQFEYAAyIIHAYKD | TIR |
SRC | P12931 | human | ITGB7 | P26010 | Y753 | YRLSVEIyDRREySR | Integrin_b_cyt |
SRC | P12931 | human | BCLAF1 | Q9NYF8 | Y408 | DtEEtEDyRQFRksV | THRAP3_BCLAF1 |
SRC | P12931 | human | PTEN | P60484 | Y174 | TIPSQRRyVyyysyL | |
SRC | P12931 | human | MYH9 | P35579 | Y158 | yAITDTAyRsMMQDr | Myosin_head |
SRC | P12931 | human | EYA3 | Q99504 | Y508 | IFPIENIySATKIGk | |
SRC | P12931 | human | PRKD2 | Q9BZL6 | Y87 | kFPECGFyGLYDkIL | |
SRC | P12931 | human | PELP1 | Q8IZL8 | Y920 | EEEDEEEyFEEEEEE | |
SRC | P12931 | human | SRRT | Q9BXP5 | Y92 | DEHSSDPyHSGYEMP | |
SRC | P12931 | human | AGO2 | Q9UKV8 | Y529 | LPGKtPVyAEVkRVG | Piwi |
SRC | P12931 | human | RMDN3 | Q96TC7 | Y176 | DAESEGGytTANAEs | |
SRC | P12931 | human | ENG | P17813 | Y612 | LLTAALWyIySHTRS | |
SRC | P12931 | human | EYA3 | Q99504 | Y90 | VPVSETAyPGQTQyQ | |
SRC | P12931 | human | CDH1 | P12830 | Y754 | DtRDNVyyyDEEGGG | |
SRC | P12931 | human | SPTAN1 | Q13813 | Y1176 | AVQQQEVyGMMPRDE | |
SRC | P12931 | human | STAP2 | Q9UGK3 | Y250 | PFLLDEDyEKVLGyV | |
SRC | P12931 | human | FCRL3 | Q96P31 | Y722 | EEDDEENyENVPRVL | |
SRC | P12931 | human | TNK2 | Q07912 | Y860 | KVsstHyyLLPERPs | |
SRC | P12931 | human | HNRNPK | P61978 | Y230 | QPyDPNFyDETyDyG | |
SRC | P12931 | human | FCRL3 | Q96P31 | Y662 | PGDSNPIySQIWSIQ | |
SRC | P12931 | human | BAIAP2L1 | Q9UHR4 | Y439 | VVIPPPDyLECLsMG | |
SRC | P12931 | human | EYA3 | Q99504 | Y208 | TILGQNQyQACYPSS | |
SRC | P12931 | human | EGFR | P00533 | Y764 | kEILDEAyVMAsVDN | PK_Tyr_Ser-Thr |
SRC | P12931 | human | PLSCR1 | O15162 | Y69 | PVPNQPVyNQPVyNQ | |
SRC | P12931 | human | EYA3 | Q99504 | S157 | GLTTSQPsPAHYSYP | |
SRC | P12931 | human | HLA-B | P01889 | Y344 | SGGkGGsySQAACsD | MHC_I_C |
SRC | P12931 | human | THOC5 | Q13769 | Y225 | EIEVKKEyLSSLQPR | FmiP_Thoc5 |
SRC | P12931 | human | CDH2 | P19022 | Y886 | GGEQDyDyLNDWGPR | CADH_Y-type_LIR |
SRC | P12931 | human | ANXA1 | P04083 | Y21 | IENEEQEyVQtVkss | |
SRC | P12931 | human | BCLAF1 | Q9NYF8 | Y81 | RGrGrGyyQGGGGry | |
SRC | P12931 | human | PPP2CA | P67775 | Y127 | SRQITQVyGFYDECL | Metallophos |
SRC | P12931 | human | CASP8 | Q14790 | Y380 | tDsEEQPyLEMDLSs | Peptidase_C14 |
SRC | P12931 | human | KCNJ1 | P48048 | Y337 | SKTKEGKyRVDFHNF | IRK_C |
SRC | P12931 | human | NRAS | P01111 | Y32 | QNHFVDEyDPTIEDs | Ras |
SRC | P12931 | human | NCKIPSD | Q9NZQ3 | Y227 | STSLDTLyTSSSPSE | |
SRC | P12931 | human | SDCBP | O00560 | Y46 | IPHDGNLyPRLyPEL | |
SRC | P12931 | human | FBXO5 | Q9UKT4 | Y142 | ALETSRLyEDsGYSs | |
SRC | P12931 | human | HSP90AB1 | P08238 | Y301 | DDItQEEyGEFyksL | HSP90 |
SRC | P12931 | human | WBP2 | Q969T9 | Y231 | AEAAASAyyNPGNPH | |
SRC | P12931 | human | USP2 | O75604 | S225 | SRVPEIIsPTYRPIG | |
SRC | P12931 | human | BDKRB2 | P30411 | Y177 | GVRWAKLysLVIWGC | TM; 7tm_1 |
SRC | P12931 | human | CTTN | Q14247 | Y470 | AyATEAVyESAEAPG | |
SRC | P12931 | human | ARAF | P10398 | Y302 | GyRDsGyyWEVPPSE | |
SRC | P12931 | human | DAPK1 | P53355 | Y491 | CAAWHGyySVAKALC | Ank_2 |
SRC | P12931 | human | TRIP10 | Q15642-3 | Y471 | ESQDTPIyTEFDEDF | |
SRC | P12931 | human | EYA3 | Q99504 | Y96 | AyPGQTQyQTLQQTQ | |
SRC | P12931 | human | GBF1 | Q92538 | Y378 | AsVHDMDyVNPRGVR | |
SRC | P12931 | human | KIF11 | P52732 | Y231 | AAtLMNAyssRSHSV | Kinesin |
SRC | P12931 | human | BCLAF1 | Q9NYF8 | Y150 | SSRSSsPysksPVsK | THRAP3_BCLAF1 |
SRC | P12931 | human | ARHGDIA | P52565 | Y27 | EDEHsVNykPPAQKs | Rho_GDI |
SRC | P12931 | human | YAP1 | P46937-3 | Y341 | PFLNSGTyHSRDEST | |
SRC | P12931 | human | HSP90AA1 | P07900 | Y197 | LkEDQtEyLEErRIk | HSP90 |
SRC | P12931 | human | FHIT | P49789 | Y114 | FHRNDsIyEELQKHD | |
SRC | P12931 | human | ATG9A | Q7Z3C6 | Y15 | yQRLEAsysDsPPGE | |
SRC | P12931 | human | SIRT2 | Q8IXJ6 | Y104 | RSPStGLyDNLEKYH | SIR2 |
SRC | P12931 | human | LPIN1 | Q14693 | Y795 | FPNTEPFyAAFGNRP | LNS2 |
SRC | P12931 | human | SLC6A4 | P31645 | Y47 | SGQISNGysAVPSPG | 5HT_transport_N |
SRC | P12931 | human | FCRL3 | Q96P31 | Y692 | HEELTVLySELKKTH | |
SRC | P12931 | human | FXN | Q16595 | Y118 | EDLADKPyTFEDYDV | Frataxin_Cyay |
SRC | P12931 | human | SHC1 | P29353 | Y350 | EPPDHQyyNDFPGKE | |
SRC | P12931 | human | G6PD | P11413 | Y428 | DLtyGNRyKNVkLPD | G6PD_C |
SRC | P12931 | human | PRKCD | Q05655 | Y313 | ssEPVGIyQGFEKkT | |
SRC | P12931 | human | PTK2 | Q05397 | Y577 | yMEDstyyKAsKGKL | PK_Tyr_Ser-Thr |
SRC | P12931 | human | STAT5A | P42229 | Y694 | LAkAVDGyVkPQIkQ | |
SRC | P12931 | human | BCLAF1 | Q9NYF8 | Y93 | GryHrGGyrPVWNRR | |
SRC | P12931 | human | PFN1 | P07737 | Y129 | GLINkkCyEMAsHLR | Profilin |
SRC | P12931 | human | SRRT | Q9BXP5 | Y798 | tPQGLMPyGQPRPPI | ARS2 |
SRC | P12931 | human | FERMT2 | Q96AC1 | Y193 | skTMTPtyDAHDGsP | |
SRC | P12931 | human | PRKCD | Q05655 | Y334 | MQDNsGtyGkIWEGs | |
SRC | P12931 | human | TUBB3 | Q13509 | Y340 | IQskNssyFVEWIPN | Tubulin_C |
SRC | P12931 | human | FUBP1 | Q96AE4 | Y268 | FREVRNEyGsRIGGN | |
SRC | P12931 | human | CASP9 | P55211 | Y251 | LQFPGAVyGTDGCPV | Peptidase_C14 |
SRC | P12931 | human | MPZL1 | O95297 | Y263 | NksEsVVyADIRKN_ | |
SRC | P12931 | human | RBM10 | P98175-2 | Y434 | SEEPPVDySYYQQDE | |
SRC | P12931 | human | HNRNPK | P61978 | Y236 | FyDETyDyGGFTMMF | |
SRC | P12931 | human | THRAP3 | Q9Y2W1 | Y68 | ErNHPrVyQNrDFrG | |
SRC | P12931 | human | CD93 | Q9NPY3 | Y644 | sRAMENQySPTPGTD | |
SRC | P12931 | human | ZC3H4 | Q9UPT8 | Y1218 | PTDRYNSyNRPRPKA | |
SRC | P12931 | human | DOK1 | Q99704 | Y362 | DPKEDPIyDEPEGLA | |
SRC | P12931 | human | EPS8 | Q12929 | Y774 | CPEGARVysQITVQk | SAM_3 |
SRC | P12931 | human | RPS6KB2 | Q9UBS0 | Y45 | GLEPVGHyEEVELTE | |
SRC | P12931 | human | PRKAA2 | P54646 | Y179 | tsCGsPNyAAPEVIS | Pkinase |
SRC | P12931 | human | RAPGEF1 | Q13905 | Y504 | APIPSVPyAPFAAIL | |
SRC | P12931 | human | AP2B1 | P63010 | Y737 | THRQGHIyMEMNFTN | Alpha_adaptinC2 |
SRC | P12931 | human | VIL1 | P09327 | Y256 | LKAALKLyHVsDsEG | |
SRC | P12931 | human | EYA3 | Q99504 | S438 | SNVGGLLsPQRKEAL | |
SRC | P12931 | human | WBP2 | Q969T9 | Y192 | MMDGAMGyVQPPPPP | |
SRC | P12931 | human | NEDD4 | P46934-4 | Y43 | ILGASDPyVRVTLYD | C2 |
SRC | P12931 | human | LPIN1 | Q14693 | Y413 | DPEVAALyFPKNGDP | |
SRC | P12931 | human | PTPRJ | Q12913 | Y1320 | NtTAMtIyENLAPVT | |
SRC | P12931 | human | TP73 | O15350 | Y28 | SLEPDStyFDLPQSS | |
SRC | P12931 | human | PTK2 | Q05397 | Y1007 | kMKLAQQyVMTSLQQ | Focal_AT |
SRC | P12931 | human | PTEN | P60484 | Y46 | AERLEGVyRNNIDDV | |
SRC | P12931 | human | GSK3B | P49841 | Y216 | RGEPNVsyICsRyyR | Pkinase |
SRC | P12931 | human | LMNA | P02545 | Y45 | LNDrLAVyIDrVRsL | Filament |
SRC | P12931 | human | DVL2 | O14641 | Y275 | VTLNMEKyNFLGISI | PDZ |
SRC | P12931 | human | ZAP70 | P43403 | Y319 | tsVyEsPysDPEELk | |
SRC | P12931 | human | HK2 | P52789 | Y686 | GTGSNACyMEEMRNV | Hexokinase_2 |
SRC | P12931 | human | CDH1 | P12830 | Y797 | tLMsVPRyLPRPANP | |
SRC | P12931 | human | EGFR | P00533 | Y1092 | tFLPVPEyINQsVPk | |
SRC | P12931 | human | CACNA1C | Q13936 | Y2217 | ELQDSRVyVSSL___ | |
SRC | P12931 | human | PTPRJ | Q12913 | Y1311 | DSkVDLIyQNtTAMt | |
SRC | P12931 | human | ETS1 | P14921 | Y283 | sLQRVPsyDsFDsED | Ets1_N_flank |
SRC | P12931 | human | DGKA | P23743 | Y335 | ILPPSSIyPSVLASG | |
SRC | P12931 | human | CTTN | Q14247 | Y334 | VTQVssAyQktVPVE | |
SRC | P12931 | human | FLOT1 | O75955 | Y56 | NVkSEkVyTRHGVPI | Band_7 |
SRC | P12931 | human | MDM2 | Q00987 | Y281 | EVyQVtVyQAGEsDt | |
SRC | P12931 | human | PRKD1 | Q15139 | Y502 | TTANVVYyVGENVVN | PH |
SRC | P12931 | human | GAB1 | Q13480 | Y373 | AsDtDssyCIPTAGM | |
SRC | P12931 | human | ZC3H4 | Q9UPT8 | Y158 | GHRKyREysPPyAPs | |
SRC | P12931 | human | FLT4 | P35916 | Y1063 | FGLARDIykDPDyVR | PK_Tyr_Ser-Thr |
SRC | P12931 | human | SHC3 | Q92529-2 | Y218 | GDGSDHPyyNSIPSK | |
SRC | P12931 | human | AKAP8 | O43823 | Y154 | RPsySyDyEFDLGSD | |
SRC | P12931 | human | SF3B2 | Q13435 | Y592 | TIHGDLyyEGKEFET | DUF382 |
SRC | P12931 | human | NEDD4 | P46934-4 | Y647 | RVAGMAVyHGKLLDG | HECT |
SRC | P12931 | human | SHC1 | P29353 | Y349 | EEPPDHQyyNDFPGK | |
SRC | P12931 | human | ELMO1 | Q92556 | Y724 | PsNyDFVyDCN____ | |
SRC | P12931 | human | EMD | P50402 | Y74 | tRGDADMyDLPkkED | |
SRC | P12931 | human | TGFBR2 | P37173 | Y284 | KIFPYEEyASWKTEk | PK_Tyr_Ser-Thr |
SRC | P12931 | human | CDH2 | P19022 | Y852 | NDPTAPPyDSLLVFD | CADH_Y-type_LIR |
SRC | P12931 | human | VIL1 | P09327 | Y60 | KTASSLSyDIHyWIG | Gelsolin |
SRC | P12931 | human | GRK2 | P25098 | Y86 | ARPLVEFyEEIKKyE | RGS |
SRC | P12931 | human | NOXA1 | Q86UR1 | Y110 | RGHAAIDyTQLGLRF | |
SRC | P12931 | human | CDKN1B | P46527 | Y88 | kGsLPEFyyRPPRPP | |
SRC | P12931 | human | CTNNB1 | P35222 | Y86 | VADIDGQyAMTRAQR | |
SRC | P12931 | human | G6PD | P11413 | Y249 | GTEGRGGyFDEFGII | G6PD_C |
SRC | P12931 | human | GRIN2A | Q12879 | Y1267 | PATGEQVyQQDWAQN | NMDAR2_C |
SRC | P12931 | human | HIPK2 | Q9H2X6 | Y361 | SkAVCstyLQsRYyR | Pkinase |
SRC | P12931 | human | HDAC3 | O15379 | Y325 | AISEELPySEyFEyF | |
SRC | P12931 | human | PKP3 | Q9Y446 | Y195 | PGGLDDRysLVsEQL | |
SRC | P12931 | human | RIPK1 | Q13546 | Y384 | kLQDEANyHLyGsRM | |
SRC | P12931 | human | AFAP1 | Q8N556 | Y93 | TSSLPEGyyEEAVPL | |
SRC | P12931 | human | SDHA | P31040 | Y215 | SLRYDTSyFVEYFAL | FAD_binding_2 |
SRC | P12931 | human | TERT | O14746 | Y707 | QDPPPELyFVKVDVT | |
SRC | P12931 | human | AKAP8 | O43823 | Y539 | IVkMLEkyLKGEDPF | AKAP95 |
SRC | P12931 | human | SHC3 | Q92529-2 | Y256 | FAGKEQTyyQGRHLG | |
SRC | P12931 | human | GIT1 | Q9Y2X7 | Y321 | FLPVNPEySATRNQG | |
SRC | P12931 | human | FLT4 | P35916 | Y1333 | ARGGQVFyNSEyGEL | |
SRC | P12931 | human | PTEN | P60484 | Y240 | RREDKFMyFEFPQPL | PTEN_C2 |
SRC | P12931 | human | NOS2 | P35228 | Y151 | IEFVNQYyGSFKEAK | NO_synthase |
SRC | P12931 | human | RPS6KA3 | P51812 | Y483 | IItLkDVyDDGKyVY | Pkinase |
SRC | P12931 | human | MYLK | Q15746 | Y464 | QEGsIEVyEDAGsHy | I-set |
SRC | P12931 | human | PPP2CA | P67775 | Y307 | VTRRtPDyFl_____ | |
SRC | P12931 | human | RAF1 | P04049 | Y341 | GQRDssyyWEIEASE | |
SRC | P12931 | human | SNCA | P37840 | Y125 | VDPDNEAyEMPsEEG | Synuclein |
SRC | P12931 | human | CORO7 | P57737 | Y758 | GDTRVFLyELLPEsP | |
SRC | P12931 | human | EYA3 | Q99504 | Y108 | QTQPyAVyPQATQTy | |
SRC | P12931 | human | PTK2 | Q05397 | Y898 | LSsPADSyNEGVKLQ | |
SRC | P12931 | human | PAK2 | Q13177 | S141 | tVkQKyLsFtPPEkd | |
SRC | P12931 | human | F11R | Q9Y624 | Y280 | tSsKkVIysQPsARs | |
SRC | P12931 | human | FHL1 | Q13642-1 | Y149 | FPkGEDFyCVTCHET | LIM |
SRC | P12931 | human | LPP | Q93052 | Y301 | GRyyEGyyAAGPGyG | |
SRC | P12931 | human | GBF1 | Q92538 | Y877 | QDILEDMyHAIKNEE | Sec7 |
SRC | P12931 | human | PPP2CA | P67775 | Y284 | ELDDTLkySFLQFDP | |
SRC | P12931 | human | TNK2 | Q07912 | Y859 | KKVsstHyyLLPERP | |
SRC | P12931 | human | GSN | P06396 | Y651 | ALGGkAAyRTsPRLK | |
SRC | P12931 | human | GBF1 | Q92538 | Y1568 | VRMQALTyLQRALLV | |
SRC | P12931 | human | PIP5K1C | O60331 | Y649 | TDERSWVysPLHYSA | |
SRC | P12931 | human | GRIN2A | Q12879 | Y1387 | GRCPSDPyKHSLPSQ | NMDAR2_C |
SRC | P12931 | human | CDKN1B | P46527 | Y74 | HkPLEGkyEWQEVEk | CDI |
SRC | P12931 | human | SRRT | Q9BXP5 | Y836 | YGAGrGNyDAFrGQG | ARS2 |
SRC | P12931 | human | SDC2 | P34741 | Y179 | RKkDEGSyDLGErkP | Syndecan |
SRC | P12931 | human | DUSP12 | Q9UNI6 | Y179 | VDTSSAIyKQYRLQK | |
SRC | P12931 | human | FLT4 | P35916 | Y853 | HLGRVLGyGAFGKVV | PK_Tyr_Ser-Thr |
SRC | P12931 | human | CD93 | Q9NPY3 | Y628 | PQNAADsysWVPERA | |
SRC | P12931 | human | KCNA3 | P22001 | Y499 | EGEEQSQyMHVGsCQ | |
SRC | P12931 | human | GBF1 | Q92538 | Y899 | TGLVRENyVWNVLLH | |
SRC | P12931 | human | SH3PXD2B | A1X283 | Y508 | DMSASAGyEEIsDPD | |
SRC | P12931 | human | IQGAP1 | P46940 | Y1510 | LVkLQQtyAALNskA | RasGAP_C |
SRC | P12931 | human | WNK4 | Q96J92 | Y1113 | PSPVWMNySySSLCL | |
SRC | P12931 | human | CHKA | P35790 | Y333 | LMLIDFEySSYNYRG | Choline_kinase |
SRC | P12931 | human | GAB1 | Q13480 | Y317 | PPtPGNtyQIPRTFP | |
SRC | P12931 | human | DAAM1 | Q9Y4D1 | Y652 | LERTFSAyQRQQDFF | FH2 |
SRC | P12931 | human | KLF16 | Q9BXK1 | Y10 | AAVACVDyFAADVLM | |
SRC | P12931 | human | STAT3 | P40763 | Y705 | DPGsAAPyLktKFIC | |
SRC | P12931 | human | CBL | P22681 | Y774 | sENEDDGyDVPKPPV | |
SRC | P12931 | human | IKBKB | O14920 | Y188 | sFVGTLQyLAPELLE | Pkinase |
SRC | P12931 | human | PTK2 | Q05397 | Y407 | IIDEEDtytMPSTRD | |
SRC | P12931 | human | MDM2 | Q00987 | Y302 | PEISLADyWKCtsCN | zf-RanBP |
SRC | P12931 | human | LRP1 | Q07954 | Y4473 | VEIGNPTyKMYEGGE | |
SRC | P12931 | human | OCLN | Q16625 | Y398 | KRtEQDHyEtDyttG | |
SRC | P12931 | human | ARHGEF2 | Q92974 | Y198 | IDEAEVIySELMSDF | |
SRC | P12931 | human | EGFR | P00533 | Y1110 | GsVQNPVyHNQPLNP | |
SRC | P12931 | human | ACLY | P53396 | Y252 | EAyPEEAyIADLDAk | Citrate_bind |
SRC | P12931 | human | WWOX | Q9NZC7 | Y33 | TTkDGWVyYANHTEE | WW |
SRC | P12931 | human | NPHS1 | O60500 | Y1176 | MAFPGHLyDEVERTY | |
SRC | P12931 | human | GRIN1 | Q05586 | Y837 | LIFIEIAyKRHKDAR | CaM_bdg_C0 |
SRC | P12931 | human | GSN | P06396-3 | Y438 | GDSYIILyNYRHGGR | Gelsolin |
SRC | P12931 | human | FLT4 | P35916 | Y1337 | QVFyNSEyGELSEPS | |
SRC | P12931 | human | CNKSR1 | Q969H4 | Y665 | KEQNRELySEGLGAW | |
SRC | P12931 | human | TNK2 | Q07912 | Y827 | SFASDPkyAtPQVIQ | Inhibitor_Mig-6 |
SRC | P12931 | human | RACK1 | P63244 | Y246 | LCFSPNryWLCAATG | WD40 |
SRC | P12931 | human | HNF4A | P41235 | Y23 | SAALDPAyTTLEFEN | |
SRC | P12931 | human | PEAK1 | Q9H792 | Y635 | IVINPNAyDNLAIyK | |
SRC | P12931 | human | DVL2 | O14641 | Y295 | ERGDGGIyIGSIMkG | PDZ |
SRC | P12931 | human | TP53 | P04637 | Y220 | rHsVVVPyEPPEVGS | P53 |
SRC | P12931 | human | CORO7 | P57737 | Y288 | GERQLYCyEVVPQQP | |
SRC | P12931 | human | VIL1 | P09327 | Y64 | SLSyDIHyWIGQDSS | Gelsolin |
SRC | P12931 | human | RHOU | Q7L0Q8 | Y254 | SkSWWKKyCCFV___ | |
SRC | P12931 | human | BAIAP2L1 | Q9UHR4 | Y163 | yEHKEIEyVEtVTSR | IMD |
SRC | P12931 | human | CDK4 | P11802 | Y17 | AEIGVGAyGTVYkAR | Pkinase |
SRC | P12931 | human | PROM1 | O43490 | Y828 | RMDsEDVyDDVEtIP | |
SRC | P12931 | human | CDCP1 | Q9H5V8 | Y762 | LQPEVDTyRPFQGTM | |
SRC | P12931 | human | ACLY | P53396 | Y1006 | PAtPLLDyALEVEkI | Citrate_synt |
SRC | P12931 | human | KDR | P35968 | Y1175 | AQQDGKDyIVLPISE | |
SRC | P12931 | human | EYA3 | Q99504 | Y237 | TTLAATTyQSEKPSV | |
SRC | P12931 | human | AFAP1 | Q8N556 | Y125 | MSSSYESyDEEEEDG | |
SRC | P12931 | human | NCKIPSD | Q9NZQ3 | Y161 | LGADGGLyQIPLPSS | |
SRC | P12931 | human | ABL1 | P00519-2 | Y488 | EGCPEKVyELMRACW | PK_Tyr_Ser-Thr |
SRC | P12931 | human | ATXN2L | Q8WWM7 | Y744 | VPGQQGKyRGAKGSL | |
SRC | P12931 | human | RPS6KA3 | P51812 | Y707 | KGAMAAtysALNRNQ | |
SRC | P12931 | human | AKAP8 | O43823 | Y146 | CLPEHNPyRPsySyD | |
SRC | P12931 | human | ARHGAP5 | Q13017 | Y1109 | kGysDEIyVVPDDsQ | RhoGAP_pG1_pG2 |
SRC | P12931 | human | AKAP8 | O43823 | Y170 | NGsFGGQySECRDPA | |
SRC | P12931 | human | CCDC88A | Q3V6T2 | Y1799 | QSkDsNPyAtLPRAS | |
SRC | P12931 | human | STAP2 | Q9UGK3 | Y22 | GVLPSHYyESFLEKK | PH |
SRC | P12931 | human | CNKSR1 | Q969H4 | Y519 | PPREEDCySETEAED | |
SRC | P12931 | human | PDHA1 | P08559 | Y289 | MELQTYRyHGHsMsD | E1_dh |
SRC | P12931 | human | KRT19 | P08727 | Y391 | LEGQEDHyNNLsAsk | |
SRC | P12931 | human | OCLN | Q16625 | Y402 | QDHyEtDyttGGEsC | |
SRC | P12931 | human | KCNB1 | Q14721 | Y128 | YWGIDEIyLESCCQA | BTB_2 |
SRC | P12931 | human | PTK2 | Q05397 | Y742 | HMVQTNHyQVSGYPG | |
SRC | P12931 | human | SOCS1 | O15524 | Y80 | LLDACGFyWGPLSVH | SH2 |
SRC | P12931 | human | RHOA | P61586 | Y34 | kDQFPEVyVPTVFEN | Ras |
SRC | P12931 | human | YAP1 | P46937-3 | Y394 | QQNRFPDyLEAIPGT | |
SRC | P12931 | human | CYP19A1 | P11511 | Y361 | KVMENFIyESMRYQP | p450 |
SRC | P12931 | human | PDPK1 | O15530 | Y373 | sEDDEDCyGNyDNLL | |
SRC | P12931 | human | KCNA3 | P22001 | Y187 | FSEEIRFyQLGEEAM | BTB_2 |
SRC | P12931 | human | SRC | P12931 | Y93 | VTTFVALyDyEsRTE | SH3_1 |
SRC | P12931 | human | PRKD1 | Q15139 | Y432 | KEGWMVHyTSKDTLR | PH |
SRC | P12931 | human | MAPT | P10636-8 | Y18 | MEDHAGtyGLGDRKD | |
SRC | P12931 | human | DLG4 | P78352 | Y523 | REDSVLSyETVTQME | |
SRC | P12931 | human | AGO2 | Q9UKV8 | Y393 | AsFNtDPyVREFGIM | ArgoL2 |
SRC | P12931 | human | GAB1 | Q13480 | Y259 | AsVDssLyNLPRSys | |
SRC | P12931 | human | EMD | P50402 | Y95 | kGyNDDyyEEsyFtT | |
SRC | P12931 | human | GLO1 | Q04760 | Y136 | GIAVPDVysACkRFE | Glyoxalase |
SRC | P12931 | human | BAIAP2L1 | Q9UHR4 | Y37 | LINLGKNyEkAVNAM | IMD |
SRC | P12931 | human | DDR2 | Q16832 | Y740 | RNLysGDyyRIQGRA | PK_Tyr_Ser-Thr |
SRC | P12931 | human | HCRTR1 | O43613 | Y358 | SAANPIIyNFLSGKF | 7tm_1; TM |
SRC | P12931 | human | FCRL3 | Q96P31 | Y650 | PMELEPMySNVNPGD | |
SRC | P12931 | human | SLC25A4 | P12235 | Y195 | RAAyFGVyDtAkGML | TM; Mito_carr |
SRC | P12931 | human | BAIAP2L1 | Q9UHR4 | Y274 | SNVVRKDyDtLskCs | |
SRC | P12931 | human | CASP8 | Q14790-4 | Y397 | TDSEEQPyLEMDLSS | Peptidase_C14 |
SRC | P12931 | human | PTEN | P60484 | Y377 | sDNEPDHyRYsDttD | |
SRC | P12931 | human | GAPDH | P04406 | Y42 | DPFIDLNyMVyMFQy | Gp_dh_N |
SRC | P12931 | human | HRAS | P01112 | Y96 | SFEDIHQyREQIKRV | Ras |
SRC | P12931 | human | GSN | P06396 | Y465 | VPVDPATyGQFYGGD | Gelsolin |
SRC | P12931 | human | GRK2 | P25098 | Y13 | AVLADVSyLMAMEkS | |
SRC | P12931 | human | GRIN2A | Q12879 | Y1325 | RLLEGNFyGSLFSVP | NMDAR2_C |
SRC | P12931 | human | STAT3 | P40763 | Y68 | LGEIDQQySRFLQES | STAT_int |
SRC | P12931 | human | CDCP1 | Q9H5V8 | Y743 | VIEDTMVyGHLLQDS | |
SRC | P12931 | human | SLC6A4 | P31645 | Y142 | MELALGQyHRNGCIs | SNF |
SRC | P12931 | human | EYA3 | Q99504 | S225 | GVTGQTNsDAESTTL | |
SRC | P12931 | human | HDAC3 | O15379 | Y328 | EELPySEyFEyFAPD | |
SRC | P12931 | human | CAV1 | Q03135 | Y14 | VDsEGHLytVPIREQ | |
SRC | P12931 | human | CHKA | P35790 | Y197 | RSLGPkLyGIFPQGR | Choline_kinase |
SRC | P12931 | human | MUC1 | P15941 | Y1229 | sstDRsPyEKVsAGN | |
SRC | P12931 | human | PDCD6IP | Q8WUM4 | Y319 | KkDNDFIyHDrVPDL | BRO1 |
SRC | P12931 | human | SHC1 | P29353 | Y427 | ELFDDPsyVNVQNLD | |
SRC | P12931 | human | CCR7 | P32248 | Y155 | LCIsIDRyVAIVQAV | 7tm_1 |
SRC | P12931 | human | KHSRP | Q92945 | Y583 | WAAYYSHyYQQPPGP | |
SRC | P12931 | human | ITGB7 | P26010 | Y758 | EIyDRREySRFEkEQ | Integrin_b_cyt |
SRC | P12931 | human | HNRNPK | P61978 | Y458 | LQNsVkQySGkFF__ | |
SRC | P12931 | human | AURKA | O14965 | Y148 | kGkFGNVyLAREKQS | Pkinase |
SRC | P12931 | human | STING1 | Q86WV6 | Y245 | RVysNSIyELLENGQ | TMEM173 |
SRC | P12931 | human | KNSTRN | Q9Y448 | Y87 | TSVVKtVySLQPPSA | |
SRC | P12931 | human | EZR | P15311 | Y478 | PPPPPPVyEPVsyHV | |
SRC | P12931 | human | GTF2I | P78347 | Y249 | ESEDPDyyQYNIQAG | |
SRC | P12931 | human | PRKD1 | Q15139 | Y95 | KFPECGFyGMYDKIL | |
SRC | P12931 | human | LPP | Q93052 | Y244 | APssGQIyGsGPQGy | |
SRC | P12931 | human | TIMP2 | P16035 | Y165 | RCPMIPCyISSPDEC | TIMP |
SRC | P12931 | human | SH3GLB1 | Q9Y371 | Y80 | ARIEEFVyEkLDRKA | BAR |
SRC | P12931 | human | AFAP1 | Q8N556 | Y453 | PEALHyDyIDVEMSA | |
SRC | P12931 | human | GRB10 | Q13322 | Y67 | NASLESLySACSMQS | |
SRC | P12931 | human | TRIP6 | Q15654 | Y55 | PLPsEQCyQAPGGPE | |
SRC | P12931 | human | EGFR | P00533 | Y1016 | DVVDADEyLIPQQGF | |
SRC | P12931 | human | RACK1 | P63244 | Y52 | LtrDEtNyGIPQRAL | |
SRC | P12931 | human | EPS8 | Q12929 | Y525 | NRHIDRNyEPLKtQP | |
SRC | P12931 | human | PANX1 | Q96RD7 | Y199 | KYPIVEQyLkTkkNS | Innexin |
SRC | P12931 | human | FLOT1 | O75955 | Y149 | MGISVVSyTLkDIHD | Band_7 |
SRC | P12931 | human | G6PD | P11413 | Y507 | GFQyEGtykWVNPHk | G6PD_C |
SRC | P12931 | human | NFE2L2 | Q16236 | Y576 | RDEDGkPysPSEYSL | |
SRC | P12931 | human | MAPRE1 | Q15691 | Y247 | QRIVDILyATDEGFV | EB1 |
SRC | P12931 | human | SRC | P12931 | Y530 | FTstEPQyQPGENL_ | |
SRC | P12931 | human | CDH5 | P33151 | Y731 | PyDTLHIyGyEGSES | CADH_Y-type_LIR |
SRC | P12931 | human | ELMO1 | Q92556 | Y720 | IPKEPsNyDFVyDCN | |
SRC | P12931 | human | AKAP8 | O43823 | Y51 | SVTTGATySyGPASW | |
SRC | P12931 | human | PLCG2 | P16885 | Y759 | LyDVsRMyVDPsEIN | |
SRC | P12931 | human | RPS6KA3 | P51812 | Y529 | TITKTVEyLHAQGVV | Pkinase |
SRC | P12931 | human | KRAS | P01116 | Y32 | QNHFVDEyDPTIEDs | Ras |
SRC | P12931 | human | RACK1 | P63244 | Y228 | LNEGkHLyTLDGGDI | WD40 |
SRC | P12931 | human | SDCBP | O00560 | Y4 | ____MsLyPsLEDLk | |
SRC | P12931 | human | CBLC | Q9ULV8 | Y341 | SEEQLQLyWAMDSTF | |
SRC | P12931 | human | NPHS1 | O60500 | Y1193 | SGAWGPLyDEVQMGP | |
SRC | P12931 | human | GSN | P06396 | Y409 | TDGLGLsyLSSHIAN | |
SRC | P12931 | human | SFPQ | P23246 | Y597 | RRQREESySRMGyMD | |
SRC | P12931 | human | TFG | Q92734 | Y33 | IHNEDITyDELVLMM | PB1 |
SRC | P12931 | human | EYA3 | Q99504 | Y72 | NDyTSQMySAKPyAH | |
SRC | P12931 | human | GJA1 | P17302 | Y247 | VKGksDPyHAtsGAL | |
SRC | P12931 | human | RPS6KA3 | P51812 | Y580 | GLLMtPCytANFVAP | Pkinase |
SRC | P12931 | human | PROM1 | O43490 | Y852 | GYHkDHVyGIHNPVM | |
SRC | P12931 | human | GTF2I | P78347-2 | Y611 | KPELVISyLPPGMAS | |
SRC | P12931 | human | ERBB2 | P04626 | Y877 | LDIDEtEyHADGGkV | PK_Tyr_Ser-Thr |
SRC | P12931 | human | PTK2 | Q05397 | Y397 | sVsEtDDyAEIIDEE | |
SRC | P12931 | human | GRIN2A | Q12879 | Y1292 | RISRQHsyDNIVDKP | NMDAR2_C |
SRC | P12931 | human | PAK3 | O75914 | S154 | VNNQKYMsFTSGDKS | |
SRC | P12931 | human | CDH2 | P19022 | Y820 | PIHAEPQyPVRsAAP | |
SRC | P12931 | human | EGFR | P00533 | Y869 | LGAEEkEyHAEGGkV | PK_Tyr_Ser-Thr |
SRC | P12931 | human | HK1 | P19367 | Y732 | YDrLVDEysLNAGkQ | Hexokinase_2 |
SRC | P12931 | human | EGFR | P00533 | Y727 | sGAFGtVykGLWIPE | PK_Tyr_Ser-Thr |
SRC | P12931 | human | HNRNPK | P61978 | Y380 | yAGGrGsyGDLGGPI | |
SRC | P12931 | human | CTTN | Q14247 | Y486 | yPAEDStyDEYENDL | |
SRC | P12931 | human | G6PD | P11413 | Y322 | EGEATkGyLDDPTVP | G6PD_C |
SRC | P12931 | human | AGO2 | Q9UKV8 | Y749 | HPTEFDFyLCsHAGI | Piwi |
SRC | P12931 | human | GSN | P06396 | Y603 | LKTPsAAyLWVGTGA | Gelsolin |
SRC | P12931 | human | FHL1 | Q13642-1 | Y272 | VFHQEQVyCPDCAkK | LIM |
SRC | P12931 | human | AFAP1 | Q8N556 | Y94 | SSLPEGyyEEAVPLs | |
SRC | P12931 | human | PTK2 | Q05397 | Y861 | PIGNQHIyQPVGKPD | |
SRC | P12931 | human | CTNNB1 | P35222 | Y333 | NIMRTytyEkLLWTT | |
SRC | P12931 | human | VIL1 | P09327 | Y81 | EQGAAAIyTTQMDDF | Gelsolin |
SRC | P12931 | human | GIT1 | Q9Y2X7 | Y246 | PDHKNGHyIIPQMAD | |
SRC | P12931 | human | PRC1 | O43663 | Y464 | QTETEMLyGsAPRtP | MAP65_ASE1 |
SRC | P12931 | human | FOS | P01100 | Y30 | AGDSLSYyHsPADSF | |
SRC | P12931 | human | THRAP3 | Q9Y2W1 | Y107 | NrGGYGNyrSNWQNy | |
SRC | P12931 | human | HCN4 | Q9Y3Q4 | Y531 | RRQYQEKyKQVEQYM | |
SRC | P12931 | human | PLD2 | O14939 | Y511 | FFWLGKDySNLITKD | |
SRC | P12931 | human | RRAS | P10301 | Y66 | DPTIEDSyTKICSVD | Ras |
SRC | P12931 | human | SLC11A1 | P49279 | Y15 | QRLSGSSyGSISSPT | |
SRC | P12931 | human | SDC4 | P31431 | Y180 | KkKDEGsyDLGKKPI | Syndecan |
SRC | P12931 | human | BAIAP2L1 | Q9UHR4 | Y293 | PAPSGRAytsPLIDM | |
SRC | P12931 | human | TNS3 | Q68CZ2 | Y1206 | sHsFRGAyGLAMKVA | SH2 |
SRC | P12931 | human | YAP1 | P46937-3 | Y357 | SGLSMSSySVPRtPD | |
SRC | P12931 | human | RPS6KA3 | P51812 | Y470 | EIEILLRyGQHPNII | Pkinase |
SRC | P12931 | human | NDFIP2 | Q9NV92 | Y167 | TTSDTEVyGEFyPVP | |
SRC | P12931 | human | STAP2 | Q9UGK3 | Y322 | GDGPAVDyENQDVAS | |
SRC | P12931 | human | TFG | Q92734 | Y247 | EGQMYQQyQQQAGYG | |
SRC | P12931 | human | AKAP8 | O43823 | Y152 | PyRPsySyDyEFDLG | |
SRC | P12931 | human | SHC1 | P29353-3 | Y195 | EPPDHQyyNDFPGKE | |
SRC | P12931 | human | PTK2 | Q05397 | Y441 | GDVHQGIyMsPENPA | PK_Tyr_Ser-Thr |
SRC | P12931 | human | RBM10 | P98175-2 | Y905 | LGArGSsyGVTSTES | |
SRC | P12931 | human | CAV2 | P51636 | Y19 | LFMDDDsysHHsGLE | Caveolin |
SRC | P12931 | human | GUCY1B1 | Q02153 | Y192 | ESKEEDFyEDLDRFE | |
SRC | P12931 | human | SDC4 | P31431 | Y197 | kAPtNEFyA______ | |
SRC | P12931 | human | CDC42 | P60953-1 | Y64 | DTAGQEDyDRLRPLS | Ras |
SRC | P12931 | human | SH3GL1 | Q99961 | Y315 | QPSCKALyDFEPEND | SH3_1 |
SRC | P12931 | human | ARHGDIB | P52566 | Y24 | ELdskLNykPPPQks | Rho_GDI |
SRC | P12931 | human | PANX1 | Q96RD7 | Y309 | KTDVLkVyEILPTFD | |
SRC | P12931 | human | EYA3 | Q99504 | Y325 | HSLLTGSyAQKYGKD | |
SRC | P12931 | human | NELFCD | Q8IXH7-4 | Y6 | __MDEDYyGSAAEWG | TH1 |
SRC | P12931 | human | CNN3 | Q15417 | Y10 | HFNkGPsyGLsAEVK | |
SRC | P12931 | human | CDH5 | P33151 | Y685 | LDARPsLyAQVQKPP | |
SRC | P12931 | human | EWSR1 | Q01844 | Y278 | HPSSMGVyGQESGGF | |
SRC | P12931 | human | AKAP8 | O43823 | Y150 | HNPyRPsySyDyEFD | |
SRC | P12931 | human | EYA3 | Q99504 | Y67 | IPRSSNDyTSQMySA | |
SRC | P12931 | human | GRIN2A | Q12879 | Y1184 | GLsNNDQyKLySKHF | NMDAR2_C |
SRC | P12931 | human | EPS8 | Q12929 | Y602 | LGRADPPytHtIQKQ | |
SRC | P12931 | human | GSN | P06396 | Y86 | VPVPTNLyGDFFTGD | Gelsolin |
SRC | P12931 | human | BCAR1 | P56945 | Y128 | SKAQQGLyQVPGPsP | |
SRC | P12931 | human | CDKN1B | P46527 | Y89 | GsLPEFyyRPPRPPK | |
SRC | P12931 | human | EGFR | P00533 | Y944 | PICtIDVyMIMVKCW | PK_Tyr_Ser-Thr |
SRC | P12931 | human | G6PD | P11413 | Y112 | NsyVAGQyDDAASYQ | G6PD_N |
SRC | P12931 | human | TIMP2 | P16035 | Y62 | VDsGNDIyGNPIkRI | TIMP |
SRC | P12931 | human | GRIN2A | Q12879 | Y1423 | SRGHNDVyISEHVMP | NMDAR2_C |
SRC | P12931 | human | EGFR | P00533 | Y1125 | APsRDPHyQDPHstA | |
SRC | P12931 | human | PBK | Q96KB5 | Y74 | NPICNDHyRsVyQkR | Pkinase |
SRC | P12931 | human | ARHGDIB | P52566 | Y153 | yGPRPEEyEFLtPVE | Rho_GDI |
SRC | P12931 | human | DVL2 | O14641 | Y463 | SDVVDWLyHHVEGFP | DEP |
SRC | P12931 | human | DNM2 | P50570 | Y597 | NtEQRNVykDLRQIE | PH |
SRC | P12931 | human | PTPN6 | P29350 | Y536 | QkGQEsEyGNItyPP | |
SRC | P12931 | human | ITGB3 | P05106 | Y773 | DtANNPLyKEAtstF | Integrin_b_cyt |
SRC | P12931 | human | PLEKHG2 | Q9H7P9 | Y489 | sEPVKDPyVMFPQNA | |
SRC | P12931 | human | DMAP1 | Q9NPF5 | Y246 | EQVAEEEyLLQELRK | DMAP1 |
SRC | P12931 | human | TRIM25 | Q14258 | Y278 | NSkFDtIyQILLkkk | |
SRC | P12931 | human | SYNJ2 | O15056 | Y490 | LLLVGDVyGEEVADK | |
SRC | P12931 | human | CEACAM1 | P13688 | Y520 | LTATEIIysEVKKQ_ | |
SRC | P12931 | human | STAT5B | P51692 | Y699 | tAkAVDGyVkPQIkQ | |
SRC | P12931 | human | RBM10 | P98175-2 | Y16 | RGDRTGRyGATDRSQ | |
SRC | P12931 | human | RAC1 | P63000 | Y64 | DTAGQEDyDRLRPLs | Ras |
SRC | P12931 | human | RGS16 | O15492 | Y168 | TLMEKDSyPRFLkSP | RGS |
SRC | P12931 | human | GRK2 | P25098 | Y92 | FyEEIKKyEkLETEE | RGS |
SRC | P12931 | human | RAF1 | P04049 | Y340 | RGQRDssyyWEIEAS | |
SRC | P12931 | human | PTEN | P60484 | Y315 | RADNDKEyLVLtLtK | PTEN_C2 |
SRC | P12931 | human | VAMP7 | P51809 | Y45 | SENNKLTySHGNYLF | Longin |
SRC | P12931 | human | PTK2 | Q05397 | Y194 | ALEKKSNyEVLEkDV | FERM_M |
SRC | P12931 | human | MEGF10 | Q96KG7 | Y1030 | LSSSENPyATIKDPP | |
SRC | P12931 | human | CDH5 | P33151 | Y658 | GEMDTTSyDVSVLNs | |
SRC | P12931 | human | CTNNB1 | P35222 | Y654 | RNEGVAtyAAAVLFR | |
SRC | P12931 | human | CCDC88C | Q9P219 | Y2025 | PQTVWyEyGCV____ | |
SRC | P12931 | human | EYA3 | Q99504 | Y105 | TLQQTQPyAVyPQAT | |
SRC | P12931 | human | NDUFV2 | P19404 | Y193 | VQINDNYyEDLTAKD | 2Fe-2S_thioredx |
SRC | P12931 | human | ARHGDIA | P52565 | Y156 | YGPRAEEyEFLtPVE | Rho_GDI |
SRC | P12931 | human | AKAP8 | O43823 | Y80 | PAMHMASyGPEPCTD | |
SRC | P12931 | human | CCDC88C | Q9P219 | Y2023 | GDPQTVWyEyGCV__ | |
SRC | P12931 | human | PLSCR1 | O15162 | Y74 | PVyNQPVyNQPVGAA | |
SRC | P12931 | human | CDH2 | P19022 | Y860 | DSLLVFDyEGSGSTA | CADH_Y-type_LIR |
SRC | P12931 | human | KHSRP | Q92945 | Y317 | GFGDrNEyGsRIGGG | |
SRC | P12931 | human | KRAS | P01116 | Y64 | DTAGQEEySAMRDQY | Ras |
SRC | P12931 | human | CHRNA7 | P36544 | Y386 | ASNGNLLyIGFRGLD | Neur_chan_memb |
SRC | P12931 | human | ESR1 | P03372 | Y537 | CKNVVPLyDLLLEML | |
SRC | P12931 | human | SDC1 | P18827 | Y286 | KkkDEGsysLEEPkQ | Syndecan |
SRC | P12931 | human | VAV3 | Q9UKW4 | Y173 | EDEGGEVyEDLMKAE | |
SRC | P12931 | human | RHOA | P61586 | Y66 | DtAGQEDyDRLRPLS | Ras |
SRC | P12931 | human | RET | P07949 | Y905 | DVyEEDsyVKRsQGR | PK_Tyr_Ser-Thr |
SRC | P12931 | human | ARHGAP35 | Q9NRY4 | Y1087 | DGFDPsDyAEPMDAV | RhoGAP_pG1_pG2 |
SRC | P12931 | human | THRAP3 | Q9Y2W1 | Y118 | WQNyrQAysPRRGRS | |
SRC | P12931 | human | GBF1 | Q92538 | Y317 | EQPGsPGySTATEPG | |
SRC | P12931 | human | CFL1 | P23528 | Y68 | GQtVDDPyAtFVkML | Cofilin_ADF |
SRC | P12931 | human | AFAP1 | Q8N556 | Y451 | TDPEALHyDyIDVEM | |
SRC | P12931 | human | FOS | P01100 | Y10 | FSGFNADyEASSSRC | |
SRC | P12931 | human | RPS6KA3 | P51812 | Y644 | KFSLSGGyWNSVSDT | Pkinase |
SRC | P12931 | human | GJA1 | P17302 | Y313 | sEQNWANysAEQNRM | Connexin43 |
SRC | P12931 | human | CHRNA7 | P36544 | Y442 | KILEEVRyIANRFRC | Neur_chan_memb |
SRC | P12931 | human | ATP1A1 | P05023 | Y149 | ITGCFSYyQEAKSSk | TM |
SRC | P12931 | human | PBK | Q96KB5 | Y272 | DFDDEAYyAALGTRP | Pkinase |
SRC | P12931 | human | ATP1A1 | P05023 | Y260 | tARGIVVytGDrtVM | E1-E2_ATPase |
SRC | P12931 | human | TNS3 | Q68CZ2 | Y1173 | QDTSkFWykADISRE | SH2 |
SRC | P12931 | human | FLT4 | P35916 | Y833 | EQCEyLSyDASQWEF | |
SRC | P12931 | human | HNRNPK | P61978 | Y225 | IkGRAQPyDPNFyDE | |
SRC | P12931 | human | ENG | P17813 | Y614 | TAALWyIySHTRSPS | |
SRC | P12931 | human | LPIN1 | Q14693 | Y398 | HLGADGVyLDDLTDM | |
SRC | P12931 | human | PTTG1IP | P53801 | Y174 | LFkEENPyARFENN_ | |
SRC | P12931 | human | CAPN2 | P17655 | Y625 | RSGtMNSyEMRkALE | |
SRC | P12931 | human | EGFR | P00533 | Y915 | MTFGSkPyDGIPASE | PK_Tyr_Ser-Thr |
SRC | P12931 | human | DDR2 | Q16832 | Y471 | EQGsNstyDrIFPLR | |
SRC | P12931 | human | NEDD4 | P46934-4 | Y585 | DGEKGLDyGGVAREW | |
SRC | P12931 | human | SPRY2 | O43597 | Y55 | AIRNTNEytEGPTVV | |
SRC | P12931 | human | ARHGEF7 | Q14155-1 | Y442 | PAPLTPAyHTLPHPS | |
SRC | P12931 | human | MPZL1 | O95297 | Y241 | sHQGPVIyAQLDHsG | |
SRC | P12931 | human | PTK2B | Q14289 | Y402 | CsIEsDIyAEIPDEt | |
SRC | P12931 | human | DVL2 | O14641 | Y27 | LDEEETPyLVkIPVP | DIX |
SRC | P12931 | human | PTPRA | P18433-2 | Y789 | yIDAFSDyANFK___ | |
SRC | P12931 | human | AR | P10275 | Y535 | MDSYSGPyGDMRLET | |
SRC | P12931 | human | AGTR1 | P30556 | Y319 | YFLQLLKyIPPKAKS | |
SRC | P12931 | human | GAK | O14976 | Y1149 | CTQPRPNyAsNFsVI | |
SRC | P12931 | human | ERBB2 | P04626 | Y1248 | PtAENPEyLGLDVPV | |
SRC | P12931 | human | TFRC | P02786 | Y20 | FGGEPLsytRFsLAR | |
SRC | P12931 | human | BCLAF1 | Q9NYF8 | Y284 | VGNGssRysPsQNsP | THRAP3_BCLAF1 |
SRC | P12931 | human | PTEN | P60484 | Y68 | HKNHYkIyNLCAERH | |
SRC | P12931 | human | WASF1 | Q92558 | Y125 | PIPLQETyDVCEQPP | |
SRC | P12931 | human | LPP | Q93052 | Y300 | QGRyyEGyyAAGPGy | |
SRC | P12931 | human | ACLY | P53396 | Y227 | KVDATADyICkVkWG | |
SRC | P12931 | human | CDC25A | P30304 | Y486 | SYCEPPSyRPMHHED | |
SRC | P12931 | human | GBF1 | Q92538 | Y1514 | HTRAASIySSWAEEQ | |
SRC | P12931 | human | PTK2 | Q05397 | Y576 | RyMEDstyyKAsKGK | PK_Tyr_Ser-Thr |
SRC | P12931 | human | MYLK | Q15746 | Y471 | yEDAGsHyLCLLKAR | I-set |
SRC | P12931 | human | EMD | P50402 | Y59 | sssAAssysFsDLNs | |
SRC | P12931 | human | HNF4A | P41235 | Y286 | LQIDDNEyAyLKAII | Hormone_recep |
SRC | P12931 | human | CDK1 | P06493 | Y15 | EkIGEGtyGVVykGR | Pkinase |
SRC | P12931 | human | ARAF | P10398 | Y301 | LGyRDsGyyWEVPPS | |
SRC | P12931 | human | CCDC88A | Q3V6T2 | Y1765 | PRktEDtyFISSAGk | |
SRC | P12931 | human | SRC | P12931 | Y338 | VVSEEPIyIVTEyMS | PK_Tyr_Ser-Thr |
SRC | P12931 | human | LDHA | P00338 | Y10 | tLkDQLIyNLLkEEQ | |
SRC | P12931 | human | TNS3 | Q68CZ2 | Y1256 | kGCsNEPyFGsLtAL | SH2 |
SRC | P12931 | human | FUBP1 | Q96AE4 | Y625 | yyRQQAAyyAQtsPQ | DUF1897 |
SRC | P12931 | human | CNN2 | Q99439 | Y12 | QFNkGPsyGLsAEVk | |
SRC | P12931 | human | CBL | P22681 | Y731 | QQIDSCTyEAMyNIQ | |
SRC | P12931 | human | CNKSR1 | Q969H4 | Y26 | LDDsLQDyPFEDWQL | SAM_1 |
SRC | P12931 | human | FER | P16591 | Y714 | RQEDGGVyssSGLkQ | PK_Tyr_Ser-Thr |
SRC | P12931 | human | CLTC | Q00610 | Y1477 | LFITEEDyQALRtSI | Clathrin |
SRC | P12931 | human | ARHGAP35 | Q9NRY4 | Y1105 | RNEEENIysVPHDst | RhoGAP_pG1_pG2 |
SRC | P12931 | human | PAK1 | Q13153 | S144 | sNsQKyMsFtDksAE | |
SRC | P12931 | human | IKBKB | O14920 | Y199 | ELLEQQKyTVTVDYW | Pkinase |
SRC | P12931 | human | RPS6KA3 | P51812 | Y488 | DVyDDGKyVYVVTEL | Pkinase |
SRC | P12931 | human | FUS | P35637 | Y526 | QDrrErPy_______ | |
SRC | P12931 | human | TP53 | P04637 | Y126 | AkSVTCTySPALNkM | P53 |
SRC | P12931 | human | CORO7 | P57737 | Y712 | SERQLLLyEAEALAG | |
SRC | P12931 | human | SRC | P12931 | Y419 | RLIEDNEytARQGAk | PK_Tyr_Ser-Thr |
SRC | P12931 | human | THRB | P10828 | Y406 | FLLAFEHyINYRKHH | Hormone_recep |
SRC | P12931 | human | WNK4 | Q96J92 | Y1115 | PVWMNySySSLCLSS | |
SRC | P12931 | human | STAT3 | P40763 | Y45 | IESQDWAyAASkESH | STAT_int |
SRC | P12931 | human | NDFIP2 | Q9NV92 | Y171 | TEVyGEFyPVPPPyS | DUF2370 |
SRC | P12931 | human | RHBG | Q9H310 | Y429 | SPPDSQHyEDQVHWQ | |
SRC | P12931 | human | LASP1 | Q14847 | Y171 | IPtsAPVyQQPQQQP | |
SRC | P12931 | human | PRKD1 | Q15139 | Y463 | NDTGsRYyKEIPLSE | PH |
SRC | P12931 | human | DDR2 | Q16832 | Y741 | NLysGDyyRIQGRAV | PK_Tyr_Ser-Thr |
SRC | P12931 | human | G3BP1 | Q13283 | Y133 | VHNDIFRyQDEVFGG | NTF2 |
SRC | P12931 | human | SHC3 | Q92529-2 | Y301 | PTGEAPTyVNTQQIP | |
SRC | P12931 | human | EZR | P15311 | Y146 | kEVHksGyLSsERLI | FERM_M |
SRC | P12931 | human | RAB34 | Q9BZG1 | Y247 | NsDDsNLyLTASkKK | |
SRC | P12931 | human | HRAS | P01112 | Y32 | QNHFVDEyDPtIEDs | Ras |
SRC | P12931 | human | CEACAM1 | P13688 | Y493 | NKMNEVtysTLNFEA | |
SRC | P12931 | human | HNRNPK | P61978 | Y72 | IkALRTDyNAsVsVP | KH_1 |
SRC | P12931 | human | FUBP1 | Q96AE4 | Y58 | TsLNsNDyGyGGQkR | |
SRC | P12931 | human | SHC3 | Q92529-2 | Y257 | AGKEQTyyQGRHLGD | |
SRC | P12931 | human | BMX | P51813 | Y566 | RYVLDDQyVsSVGTK | PK_Tyr_Ser-Thr |
SRC | P12931 | human | JUP | P14923 | Y644 | RNEGTATyAAAVLFR | |
SRC | P12931 | human | KHSRP | Q92945 | Y688 | yYRQQAAyYGQtPGP | DUF1897 |
SRC | P12931 | human | CORO7 | P57737 | Y738 | PSTLLPSyDPDTGLV | |
SRC | P12931 | human | GBF1 | Q92538 | Y1488 | DEGVPASyHTVSLQV | |
SRC | P12931 | human | PXN | P49023 | Y88 | PQsssPVyGsSAKTs | Paxillin |
SRC | P12931 | human | SHC3 | Q92529-2 | Y283 | RQGSSDIySTPEGKL | |
SRC | P12931 | human | LRP1 | Q07954 | Y4507 | TNFTNPVyATLyMGG | |
SRC | P12931 | human | XRCC6 | P12956 | Y530 | DEFkELVyPPDyNPE | Ku_C |
SRC | P12931 | human | SHC3 | Q92529-2 | Y219 | DGSDHPyyNSIPSKM | |
SRC | P12931 | human | VIL1 | P09327 | Y46 | SFFDGDCyIILAIHK | Gelsolin |
SRC | P12931 | human | FIP1L1 | Q6UN15 | Y110 | IKTGAPQyGsyGTAP | |
SRC | P12931 | human | ITGB3 | P05106 | Y785 | stFTNItyRGT____ | Integrin_b_cyt |
SRC | P12931 | human | NPHP1 | O15259 | Y721 | FDLSEQTyDFLGEMR | |
SRC | P12931 | human | DAPP1 | Q9UN19 | Y139 | kVEEPsIyEsVRVHT | |
SRC | P12931 | human | OTUB1 | Q96FW1 | Y26 | EGVNCLAyDEAIMAQ | |
SRC | P12931 | human | EYA3 | Q99504 | Y532 | RFGKkVTyVVIGDGR | |
SRC | P12931 | human | GAB1 | Q13480 | Y627 | KGDKQVEyLDLDLDs | |
SRC | P12931 | human | PKD1 | P98161 | Y4237 | NQATEDVyQLEQQLH | |
SRC | P12931 | human | PRMT5 | O14744 | Y324 | DNLESQTyEVFEkDP | PRMT5 |
SRC | P12931 | human | GAK | O14976 | Y412 | kGDLDISyITSRIAV | |
SRC | P12931 | human | KCND3 | Q9UK17 | Y108 | GKLHYPRyECISAYD | BTB_2 |
SRC | P12931 | human | STAT1 | P42224 | Y701 | DGPkGtGyIktELIs | |
SRC | P12931 | human | AKAP8 | O43823 | Y311 | KRkQFQLyEEPDTkL | |
SRC | P12931 | human | NEDD4 | P46934-4 | Y111 | GQVDVPLyPLPTENP | C2 |
SRC | P12931 | human | KIF11 | P52732 | Y125 | ERsPNEEytWEEDPL | Kinesin |
SRC | P12931 | human | GBF1 | Q92538 | Y1245 | RVSHQVAyGLHELLK | |
SRC | P12931 | human | ARHGEF4 | Q9NR80-3 | Y94 | VGSEEDLyDDLHSSS | |
SRC | P12931 | human | AKAP8 | O43823 | Y436 | TVEFLQEyIVNRNKK | AKAP95 |
SRC | P12931 | human | MMP14 | P50281 | Y573 | GtPRRLLyCQRsLLD | DUF3377 |
SRC | P12931 | human | SRRT | Q9BXP5 | Y175 | AVKRyNDyKLDFRRQ | SERRATE_Ars2_N |
SRC | P12931 | human | IKBKG | Q9Y6K9 | Y374 | PLPPAPAyLssPLAL |
Biological Network Integration of This Kinase and Substrates (GeneMANIA website) |
Enriched GO biological processes of the phosphorylation target genes of the kinase |
Kinase | GOID | GO term | P.adjust |
SRC | ID | Description | 0.00e+00 |
SRC | GO:1902903 | regulation of supramolecular fiber organization | 2.58e-17 |
SRC | GO:0043254 | regulation of protein-containing complex assembly | 2.58e-17 |
SRC | GO:0034329 | cell junction assembly | 2.58e-17 |
SRC | GO:0032970 | regulation of actin filament-based process | 2.69e-17 |
SRC | GO:0031334 | positive regulation of protein-containing complex assembly | 2.98e-16 |
SRC | GO:0051347 | positive regulation of transferase activity | 3.83e-16 |
SRC | GO:0001667 | ameboidal-type cell migration | 5.54e-16 |
SRC | GO:1901653 | cellular response to peptide | 5.54e-16 |
SRC | GO:1902905 | positive regulation of supramolecular fiber organization | 9.24e-16 |
SRC | GO:0033674 | positive regulation of kinase activity | 1.01e-15 |
SRC | GO:0018105 | peptidyl-serine phosphorylation | 1.14e-15 |
SRC | GO:0007015 | actin filament organization | 1.37e-15 |
SRC | GO:0051495 | positive regulation of cytoskeleton organization | 2.31e-15 |
SRC | GO:0018209 | peptidyl-serine modification | 3.22e-15 |
SRC | GO:0071375 | cellular response to peptide hormone stimulus | 3.64e-15 |
SRC | GO:0007264 | small GTPase mediated signal transduction | 7.14e-15 |
SRC | GO:0032271 | regulation of protein polymerization | 2.38e-14 |
SRC | GO:0032956 | regulation of actin cytoskeleton organization | 3.51e-14 |
SRC | GO:0007173 | epidermal growth factor receptor signaling pathway | 4.18e-14 |
SRC | GO:0007265 | Ras protein signal transduction | 4.45e-14 |
SRC | GO:0002764 | immune response-regulating signaling pathway | 6.00e-14 |
SRC | GO:0002757 | immune response-activating signaling pathway | 6.00e-14 |
SRC | GO:0042060 | wound healing | 6.98e-14 |
SRC | GO:0006909 | phagocytosis | 7.49e-14 |
SRC | GO:0043434 | response to peptide hormone | 1.06e-13 |
SRC | GO:0051258 | protein polymerization | 1.23e-13 |
SRC | GO:0007163 | establishment or maintenance of cell polarity | 2.34e-13 |
SRC | GO:0110053 | regulation of actin filament organization | 2.75e-13 |
SRC | GO:0006898 | receptor-mediated endocytosis | 5.26e-13 |
SRC | GO:0038127 | ERBB signaling pathway | 5.28e-13 |
SRC | GO:0045860 | positive regulation of protein kinase activity | 5.73e-13 |
SRC | GO:0007160 | cell-matrix adhesion | 6.22e-13 |
SRC | GO:0007044 | cell-substrate junction assembly | 6.26e-13 |
SRC | GO:0048041 | focal adhesion assembly | 1.37e-12 |
SRC | GO:0062197 | cellular response to chemical stress | 1.38e-12 |
SRC | GO:0043410 | positive regulation of MAPK cascade | 1.42e-12 |
SRC | GO:0150115 | cell-substrate junction organization | 2.07e-12 |
SRC | GO:0045785 | positive regulation of cell adhesion | 2.22e-12 |
SRC | GO:0010634 | positive regulation of epithelial cell migration | 3.94e-12 |
SRC | GO:0016049 | cell growth | 5.25e-12 |
SRC | GO:0046777 | protein autophosphorylation | 5.31e-12 |
SRC | GO:0001952 | regulation of cell-matrix adhesion | 5.77e-12 |
SRC | GO:1903829 | positive regulation of protein localization | 7.69e-12 |
SRC | GO:0032535 | regulation of cellular component size | 9.22e-12 |
SRC | GO:0045766 | positive regulation of angiogenesis | 9.48e-12 |
SRC | GO:1904018 | positive regulation of vasculature development | 9.48e-12 |
SRC | GO:2001233 | regulation of apoptotic signaling pathway | 9.60e-12 |
SRC | GO:0018108 | peptidyl-tyrosine phosphorylation | 1.26e-11 |
SRC | GO:0045936 | negative regulation of phosphate metabolic process | 1.26e-11 |
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Related Drugs to ITCH_SRC |
Drugs used for this fusion-positive patient. (Manual curation of PubMed, 04-30-2022 + MyCancerGenome) |
Hgene | Tgene | Drug | Source | PMID |
Distribution of the number of studies mentioning ITCH-SRC and kinase inhibitors the PubMed Abstract (04-01-2024) |
Fusion gene - drug pair 1 | Fusion gene - drug pair 2 | PMID | Publication date | DOI | Study title |
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Related Diseases to ITCH_SRC |
Diseases that have this fusion gene. (Manual curation of PubMed, 04-30-2022 + MyCancerGenome) |
Hgene | Tgene | Disease | Source | PMID |
Related diseases from the literature mentioned this fusion gene and drug. (PubMed, 04-01-2024) |
MeSH ID | MeSH term |
Diseases associated with fusion partners. (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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Clinical Trials of the Found Drugs/Small Molecules |
Statistics of the Clinical Trials of the Found Kinase Inibitors from clinicaltrials.gov (06-17-2024) |
Clinical Trials from clinicaltrials.gov (06-17-2024) |
Fusion Gene | Kinase Inhibitor | NCT ID | Study Status | Phases | Disease | # Enrolment | Date |