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Kinase Fusion Gene:ZNF219_CSNK1D |
Kinase Fusion Protein Summary |
Kinase Fusion gene summary |
Kinase Fusion partner gene information | Kinase Fusion gene name: ZNF219_CSNK1D | KinaseFusionDB ID: KFG7268 | FusionGDB2.0 ID: KFG7268 | Hgene | Tgene | Gene symbol | ZNF219 | CSNK1D | Gene ID | 51222 | 1453 | |
Gene name | zinc finger protein 219 | casein kinase 1 delta | ||||||||||
Synonyms | ZFP219 | ASPS|CKI-delta|CKId|CKIdelta|FASPS2|HCKID | ||||||||||
Cytomap | 14q11.2 | 17q25.3 | ||||||||||
Type of gene | protein-coding | protein-coding | ||||||||||
Description | zinc finger protein 219 | casein kinase I isoform deltacasein kinase Itau-protein kinase CSNK1D | ||||||||||
Modification date | 20240305 | 20240407 | ||||||||||
UniProtAcc | Q9P2Y4 | P48730 | ||||||||||
Ensembl transtripts involved in fusion gene | ENST ids | ENST00000360947, ENST00000451119, ENST00000421093, ENST00000556101, | ENST00000398519, ENST00000314028, ENST00000392334, ENST00000578904, | |||||||||
Context (manual curation of fusion genes in KinaseFusionDB) | PubMed: ZNF219 [Title/Abstract] AND CSNK1D [Title/Abstract] AND fusion [Title/Abstract] | |||||||||||
Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0) |
Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
Partner | Gene | GO ID | GO term | PubMed ID |
Hgene | ZNF219 | GO:0000122 | negative regulation of transcription by RNA polymerase II | 14621294 |
Hgene | ZNF219 | GO:0045892 | negative regulation of DNA-templated transcription | 14621294 |
Tgene | CSNK1D | GO:0006468 | protein phosphorylation | 16618118 |
Tgene | CSNK1D | GO:0051225 | spindle assembly | 10826492 |
Kinase Fusion gene breakpoints across ZNF219 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
Kinase Fusion gene breakpoints across CSNK1D (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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Kinase Fusion Gene Sample Information |
Kinase Fusion gene information. |
Kinase Fusion gene information from four resources (ChiTars 5.0, ChimerDB 4.0, COSMIC, and CCLE) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Source | Sample | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp |
CCLE | ETCC-016 | ZNF219 | chr14 | 21571262 | CSNK1D | chr17 | 80223672 |
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Kinase Fusion ORF Analysis |
Kinase Fusion information from ORFfinder translation from full-length transcript sequence from KinaseFusionDB. |
Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | Seq length (transcript) | Seq length (amino acids) |
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Kinase Fusion Amino Acid Sequences |
For individual full-length fusion transcript sequence from KinaseFusionDB, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
>Henst_Tenst_Hgene_Hchr_Hbp_Tgene_Tchr_Tbp_length(fusion AA)_AAseq |
Multiple Sequence Alignment of All Fusion Protein Isoforms |
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Kinase Fusion Protein Functional Features |
Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/:/:) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
Main function of each fusion partner protein. (from UniProt) |
Hgene | Tgene |
ZNF219 | CSNK1D |
FUNCTION: Transcriptional regulator (PubMed:14621294, PubMed:19549071). Recognizes and binds 2 copies of the core DNA sequence motif 5'-GGGGG-3' (PubMed:14621294). Binds to the HMGN1 promoter and may repress HMGN1 expression (PubMed:14621294). Regulates SNCA expression in primary cortical neurons (PubMed:19549071). Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with SOX9 (By similarity). Plays a role in chondrocyte differentiation (By similarity). {ECO:0000250|UniProtKB:Q6IQX8, ECO:0000269|PubMed:14621294, ECO:0000269|PubMed:19549071}. | FUNCTION: Essential serine/threonine-protein kinase that regulates diverse cellular growth and survival processes including Wnt signaling, DNA repair and circadian rhythms. It can phosphorylate a large number of proteins. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Phosphorylates connexin-43/GJA1, MAP1A, SNAPIN, MAPT/TAU, TOP2A, DCK, HIF1A, EIF6, p53/TP53, DVL2, DVL3, ESR1, AIB1/NCOA3, DNMT1, PKD2, YAP1, PER1 and PER2. Central component of the circadian clock. In balance with PP1, determines the circadian period length through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. Controls PER1 and PER2 nuclear transport and degradation. YAP1 phosphorylation promotes its SCF(beta-TRCP) E3 ubiquitin ligase-mediated ubiquitination and subsequent degradation. DNMT1 phosphorylation reduces its DNA-binding activity. Phosphorylation of ESR1 and AIB1/NCOA3 stimulates their activity and coactivation. Phosphorylation of DVL2 and DVL3 regulates WNT3A signaling pathway that controls neurite outgrowth. Phosphorylates NEDD9/HEF1 (By similarity). EIF6 phosphorylation promotes its nuclear export. Triggers down-regulation of dopamine receptors in the forebrain. Activates DCK in vitro by phosphorylation. TOP2A phosphorylation favors DNA cleavable complex formation. May regulate the formation of the mitotic spindle apparatus in extravillous trophoblast. Modulates connexin-43/GJA1 gap junction assembly by phosphorylation. Probably involved in lymphocyte physiology. Regulates fast synaptic transmission mediated by glutamate. {ECO:0000250|UniProtKB:Q9DC28, ECO:0000269|PubMed:10606744, ECO:0000269|PubMed:12270943, ECO:0000269|PubMed:14761950, ECO:0000269|PubMed:16027726, ECO:0000269|PubMed:17562708, ECO:0000269|PubMed:17962809, ECO:0000269|PubMed:19043076, ECO:0000269|PubMed:20041275, ECO:0000269|PubMed:20048001, ECO:0000269|PubMed:20407760, ECO:0000269|PubMed:20637175, ECO:0000269|PubMed:20696890, ECO:0000269|PubMed:20699359, ECO:0000269|PubMed:21084295, ECO:0000269|PubMed:21422228, ECO:0000269|PubMed:23636092}. |
Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
- Retained domain in the 5'-partner of fusion protein (protein functional feature from UniProt). |
Partner | Hgeneene | Hbp | Tgeneene | Tbp | ENST | BPexon | TotalExon | Protein feature loci | BPloci | TotalLen | Feature | Note |
- Retained domain in the 3'-partner of fusion protein (protein functional feature from UniProt). |
Partner | Hgeneene | Hbp | Tgeneene | Tbp | ENST | BPexon | TotalExon | Protein feature loci | BPloci | TotalLen | Feature | Note |
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Kinase-Substrate Information of ZNF219_CSNK1D |
Phosphorylation target of the kinase (phosphosite, 03-17-2024) |
Kinase | Kinase UniProt Acc | Kinase species | Substrate | Substrate UniProt Acc | Substrate phosphorylated residues | Substrate phosphorylated sites (+/-7AA) | Domain |
CSNK1D | P48730 | human | EPAS1 | Q99814 | T528 | FNELDLEtLAPYIPM | HIF-1 |
CSNK1D | P48730 | human | TARDBP | Q13148 | S393 | GsAsNAGsGsGFNGG | |
CSNK1D | P48730 | human | LZTS2 | Q9BRK4 | S224 | LSDsGRNsLSSLPTY | |
CSNK1D | P48730 | human | FUS | P35637 | S163 | GQQNQYNssSGGGGG | |
CSNK1D | P48730 | human | SNCA | P37840 | T64 | EktkEQVtNVGGAVV | Synuclein |
CSNK1D | P48730 | human | YAP1 | P46937 | S400 | SRDEstDsGLsMsSy | |
CSNK1D | P48730 | human | MDM2 | Q00987 | T351 | kAkLENstQAEEGFD | |
CSNK1D | P48730 | human | MDM2 | Q00987 | S386 | DDKITQAsQsQESED | |
CSNK1D | P48730 | human | BACE1 | P56817 | S498 | DDFADDIsLLk____ | |
CSNK1D | P48730 | human | SMARCA4 | P51532 | S35 | LGPsPGPsPGSAHSM | |
CSNK1D | P48730 | human | APC | P25054 | S1507 | FsCsssLsALsLDEP | APC_r |
CSNK1D | P48730 | human | MDM2 | Q00987 | S260 | sLDsEDYsLsEEGQE | |
CSNK1D | P48730 | human | MDM2 | Q00987 | S350 | EkAkLENstQAEEGF | |
CSNK1D | P48730 | human | TP53 | P04637 | S9 | EEPQsDPsVEPPLsQ | P53_TAD |
CSNK1D | P48730 | human | LZTS2 | Q9BRK4 | S273 | TGPsHsDsGRsssSK | |
CSNK1D | P48730 | human | TP53 | P04637 | T18 | EPPLsQEtFsDLWkL | P53_TAD |
CSNK1D | P48730 | human | MAPT | P10636-8 | S396 | GAEIVyKsPVVsGDt | |
CSNK1D | P48730 | human | MAPT | P10636-8 | S404 | PVVsGDtsPRHLsNV | |
CSNK1D | P48730 | human | FUS | P35637 | S183 | NYGQDQssMSSGGGS | |
CSNK1D | P48730 | human | EPAS1 | Q99814 | S383 | SSGKGAVsEkSNFLF | |
CSNK1D | P48730 | human | CTNNB1 | P35222 | S45 | GATtTAPsLsGkGNP | |
CSNK1D | P48730 | human | MDM2 | Q00987 | S172 | IsEtEENsDELsGER | |
CSNK1D | P48730 | human | LRP6 | O75581 | S1490 | AILNPPPsPAtERsH | |
CSNK1D | P48730 | human | DCK | P27707 | S11 | PPKRsCPsFsAssEG | |
CSNK1D | P48730 | human | TARDBP | Q13148 | S317 | GMNFGAFsINPAMMA | |
CSNK1D | P48730 | human | TARDBP | Q13148 | S409 | GssMDskssGWGM__ | |
CSNK1D | P48730 | human | FUS | P35637 | S182 | GNYGQDQssMSSGGG | |
CSNK1D | P48730 | human | UHRF1 | Q96T88 | S95 | sELsDtDsGCCLGQS | |
CSNK1D | P48730 | human | SMARCA4 | P51532 | S31 | PGAMLGPsPGPsPGS | |
CSNK1D | P48730 | human | LZTS2 | Q9BRK4 | S220 | PSGTLSDsGRNsLSS | |
CSNK1D | P48730 | human | FUS | P35637 | S221 | GGrGrGGsGGGGGGG | |
CSNK1D | P48730 | human | MDM2 | Q00987 | T365 | DVPDCkktIVNDSRE | |
CSNK1D | P48730 | human | YAP1 | P46937 | S403 | EstDsGLsMsSySVP | |
CSNK1D | P48730 | human | NEDD9 | Q14511 | T804 | AALHYPStTALQEMV | CAS_C |
CSNK1D | P48730 | human | APC | P25054 | S1510 | sssLsALsLDEPFIQ | |
CSNK1D | P48730 | human | PRKD2 | Q9BZL6 | S244 | sssSssAssyTGRPI | |
CSNK1D | P48730 | human | MDM2 | Q00987 | S176 | EENsDELsGERQRkR | |
CSNK1D | P48730 | human | NCOA3 | Q9Y6Q9 | S601 | SDKESKEsSVEGAEN | |
CSNK1D | P48730 | human | MDM2 | Q00987 | S229 | PDLDAGVsEHSGDWL | |
CSNK1D | P48730 | human | APC | P25054 | S1504 | PDGFsCsssLsALsL | APC_r |
CSNK1D | P48730 | human | MDM2 | Q00987 | S269 | sEEGQELsDEDDEVy | |
CSNK1D | P48730 | human | TOP2B | Q02880-2 | S1130 | HDDSSSDsGTPsGPD | DNA_topoisoIV |
CSNK1D | P48730 | human | TARDBP | Q13148 | S305 | GLGNNQGsNMGGGMN | |
CSNK1D | P48730 | human | WEE1 | P30291 | S212 | SVkLRGssLFMDtEK | |
CSNK1D | P48730 | human | FUS | P35637 | S273 | GGPrDQGsRHDsEQD | |
CSNK1D | P48730 | human | HIF1A | Q16665 | S247 | KTFLSRHsLDMkFSY | |
CSNK1D | P48730 | human | ZNF322 | Q6U7Q0 | S396 | ELsPPHAsEAsQMS_ | |
CSNK1D | P48730 | human | PER2 | O15055 | S662 | ALPGKAEsVAsLTsQ | |
CSNK1D | P48730 | human | DCK | P27707 | T72 | QDEFEELtMsQkNGG | dNK |
CSNK1D | P48730 | human | MAPT | P10636-8 | S202 | sGyssPGsPGtPGsR | |
CSNK1D | P48730 | human | FUS | P35637 | S346 | VsFDDPPsAkAAIDW | RRM_1 |
CSNK1D | P48730 | human | DVL2 | O14641 | S143 | FHPNVSssHENLEPE | Dishevelled |
CSNK1D | P48730 | human | TARDBP | Q13148 | S410 | ssMDskssGWGM___ | |
CSNK1D | P48730 | human | PPP5C | P53041 | T362 | LFSEDGVtLDDIRKI | Metallophos |
CSNK1D | P48730 | human | MDM2 | Q00987 | S220 | SESTGtPsNPDLDAG | |
CSNK1D | P48730 | human | MDM2 | Q00987 | S262 | DsEDYsLsEEGQELs | |
CSNK1D | P48730 | human | CDH1 | P12830 | S844 | GsGsEAAsLSsLNsS | CADH_Y-type_LIR |
CSNK1D | P48730 | human | DCK | P27707 | S15 | sCPsFsAssEGtRIK | |
CSNK1D | P48730 | human | TARDBP | Q13148 | S333 | AQAALQSsWGMMGML | |
CSNK1D | P48730 | human | TARDBP | Q13148 | S395 | AsNAGsGsGFNGGFG | |
CSNK1D | P48730 | human | MDM2 | Q00987 | S342 | GkDkGEIsEkAkLEN | |
CSNK1D | P48730 | human | FUS | P35637 | S462 | PGGGPGGsHMGGNyG | |
CSNK1D | P48730 | human | MDM2 | Q00987 | S166 | SsRRRAIsEtEENsD | |
CSNK1D | P48730 | human | DVL2 | O14641 | T224 | MSRFssStEQSsASR | Dishevelled |
CSNK1D | P48730 | human | TARDBP | Q13148 | S403 | GFNGGFGssMDskss | |
CSNK1D | P48730 | human | FUS | P35637 | S277 | DQGsRHDsEQDNSDN | |
CSNK1D | P48730 | human | MDM2 | Q00987 | T419 | KEFEREEtQDKEEsV | |
CSNK1D | P48730 | human | PER2 | O15055 | S668 | EsVAsLTsQCsYSST | |
CSNK1D | P48730 | human | DCK | P27707 | S74 | EFEELtMsQkNGGNV | dNK |
CSNK1D | P48730 | human | TARDBP | Q13148 | S404 | FNGGFGssMDskssG | |
CSNK1D | P48730 | human | FUS | P35637 | T338 | GkLkGEAtVsFDDPP | |
CSNK1D | P48730 | human | PSEN2 | P49810 | S330 | MEEDsYDsFGEPsYP | Presenilin; Presenilin |
CSNK1D | P48730 | human | TP53 | P04637 | S20 | PLsQEtFsDLWkLLP | P53_TAD |
CSNK1D | P48730 | human | MDM2 | Q00987 | S373 | IVNDSREsCVEENDD | |
CSNK1D | P48730 | human | TARDBP | Q13148 | S389 | AIGWGsAsNAGsGsG | |
CSNK1D | P48730 | human | NEDD9 | Q14511 | S780 | RNkVMNSsNQLCEQL | CAS_C |
CSNK1D | P48730 | human | MDM2 | Q00987 | S290 | AGEsDtDsFEEDPEI | |
CSNK1D | P48730 | human | YAP1 | P46937-2 | S384 | SRDEsTDsGLsMSSY | |
CSNK1D | P48730 | human | MDM2 | Q00987 | S118 | NQQESSDsGTsVSEN | |
CSNK1D | P48730 | human | TARDBP | Q13148 | S292 | NQGGFGNsrGGGAGL | |
CSNK1D | P48730 | human | PER2 | O15055 | S665 | GKAEsVAsLTsQCsY | |
CSNK1D | P48730 | human | LZTS2 | Q9BRK4 | S277 | HsDsGRsssSKsTGS | |
CSNK1D | P48730 | human | TARDBP | Q13148 | S92 | MDEtDAssAVkVKRA | |
CSNK1D | P48730 | human | APC | P25054 | S1505 | DGFsCsssLsALsLD | APC_r |
CSNK1D | P48730 | human | MTSS1 | O43312 | S322 | SSVsSHDsGFISQDA | |
CSNK1D | P48730 | human | MDM2 | Q00987 | S253 | sVEFEVEsLDsEDYs | |
CSNK1D | P48730 | human | KIR3DL1 | P43629 | S388 | RTANsEDsDEQDPEE | |
CSNK1D | P48730 | human | PSEN2 | P49810 | S327 | DPEMEEDsYDsFGEP | Presenilin; Presenilin |
CSNK1D | P48730 | human | FUS | P35637 | S164 | QQNQYNssSGGGGGG | |
CSNK1D | P48730 | human | MDM2 | Q00987 | S121 | ESSDsGTsVSENRCH | |
CSNK1D | P48730 | human | MAPT | P10636-8 | T205 | ssPGsPGtPGsRsRt | |
CSNK1D | P48730 | human | KIR3DL1 | P43629 | S385 | AGNRTANsEDsDEQD | |
CSNK1D | P48730 | human | MDM2 | Q00987 | S240 | GDWLDQDsVsDQFsV | |
CSNK1D | P48730 | human | MDM2 | Q00987 | T279 | DDEVyQVtVyQAGEs |
Biological Network Integration of This Kinase and Substrates (GeneMANIA website) |
Enriched GO biological processes of the phosphorylation target genes of the kinase |
Kinase | GOID | GO term | P.adjust |
CSNK1D | ID | Description | 0.00e+00 |
CSNK1D | GO:1990000 | amyloid fibril formation | 9.50e-08 |
CSNK1D | GO:1903829 | positive regulation of protein localization | 3.40e-05 |
CSNK1D | GO:0034599 | cellular response to oxidative stress | 7.44e-05 |
CSNK1D | GO:0003007 | heart morphogenesis | 7.44e-05 |
CSNK1D | GO:0062197 | cellular response to chemical stress | 2.05e-04 |
CSNK1D | GO:0060562 | epithelial tube morphogenesis | 2.43e-04 |
CSNK1D | GO:1902459 | positive regulation of stem cell population maintenance | 2.88e-04 |
CSNK1D | GO:0010038 | response to metal ion | 2.88e-04 |
CSNK1D | GO:0072160 | nephron tubule epithelial cell differentiation | 2.88e-04 |
CSNK1D | GO:0050767 | regulation of neurogenesis | 4.10e-04 |
CSNK1D | GO:0006979 | response to oxidative stress | 4.40e-04 |
CSNK1D | GO:0006089 | lactate metabolic process | 4.82e-04 |
CSNK1D | GO:0031400 | negative regulation of protein modification process | 6.68e-04 |
CSNK1D | GO:0010288 | response to lead ion | 6.71e-04 |
CSNK1D | GO:2000036 | regulation of stem cell population maintenance | 7.26e-04 |
CSNK1D | GO:0016055 | Wnt signaling pathway | 7.26e-04 |
CSNK1D | GO:0198738 | cell-cell signaling by wnt | 7.26e-04 |
CSNK1D | GO:0051960 | regulation of nervous system development | 7.35e-04 |
CSNK1D | GO:0006302 | double-strand break repair | 7.41e-04 |
CSNK1D | GO:0034504 | protein localization to nucleus | 7.41e-04 |
CSNK1D | GO:0060070 | canonical Wnt signaling pathway | 7.41e-04 |
CSNK1D | GO:0019827 | stem cell population maintenance | 7.41e-04 |
CSNK1D | GO:2000045 | regulation of G1/S transition of mitotic cell cycle | 7.41e-04 |
CSNK1D | GO:0035050 | embryonic heart tube development | 7.41e-04 |
CSNK1D | GO:0048771 | tissue remodeling | 7.41e-04 |
CSNK1D | GO:2000134 | negative regulation of G1/S transition of mitotic cell cycle | 7.41e-04 |
CSNK1D | GO:0071480 | cellular response to gamma radiation | 7.41e-04 |
CSNK1D | GO:0098727 | maintenance of cell number | 7.41e-04 |
CSNK1D | GO:0060485 | mesenchyme development | 7.41e-04 |
CSNK1D | GO:0010039 | response to iron ion | 9.47e-04 |
CSNK1D | GO:1902807 | negative regulation of cell cycle G1/S phase transition | 9.58e-04 |
CSNK1D | GO:1902806 | regulation of cell cycle G1/S phase transition | 1.09e-03 |
CSNK1D | GO:0072080 | nephron tubule development | 1.09e-03 |
CSNK1D | GO:0120162 | positive regulation of cold-induced thermogenesis | 1.09e-03 |
CSNK1D | GO:0043618 | regulation of transcription from RNA polymerase II promoter in response to stress | 1.09e-03 |
CSNK1D | GO:0097306 | cellular response to alcohol | 1.14e-03 |
CSNK1D | GO:0061326 | renal tubule development | 1.15e-03 |
CSNK1D | GO:0045936 | negative regulation of phosphate metabolic process | 1.23e-03 |
CSNK1D | GO:0010563 | negative regulation of phosphorus metabolic process | 1.23e-03 |
CSNK1D | GO:0051348 | negative regulation of transferase activity | 1.28e-03 |
CSNK1D | GO:0043523 | regulation of neuron apoptotic process | 1.45e-03 |
CSNK1D | GO:0043620 | regulation of DNA-templated transcription in response to stress | 1.51e-03 |
CSNK1D | GO:0070232 | regulation of T cell apoptotic process | 1.59e-03 |
CSNK1D | GO:0050678 | regulation of epithelial cell proliferation | 1.61e-03 |
CSNK1D | GO:0072009 | nephron epithelium development | 1.61e-03 |
CSNK1D | GO:0051091 | positive regulation of DNA-binding transcription factor activity | 1.61e-03 |
CSNK1D | GO:0060560 | developmental growth involved in morphogenesis | 1.61e-03 |
CSNK1D | GO:0048863 | stem cell differentiation | 1.62e-03 |
CSNK1D | GO:0071542 | dopaminergic neuron differentiation | 1.62e-03 |
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Related Drugs to ZNF219_CSNK1D |
Drugs used for this fusion-positive patient. (Manual curation of PubMed, 04-30-2022 + MyCancerGenome) |
Hgene | Tgene | Drug | Source | PMID |
Distribution of the number of studies mentioning ZNF219-CSNK1D and kinase inhibitors the PubMed Abstract (04-01-2024) |
Fusion gene - drug pair 1 | Fusion gene - drug pair 2 | PMID | Publication date | DOI | Study title |
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Related Diseases to ZNF219_CSNK1D |
Diseases that have this fusion gene. (Manual curation of PubMed, 04-30-2022 + MyCancerGenome) |
Hgene | Tgene | Disease | Source | PMID |
Related diseases from the literature mentioned this fusion gene and drug. (PubMed, 04-01-2024) |
MeSH ID | MeSH term |
Diseases associated with fusion partners. (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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Clinical Trials of the Found Drugs/Small Molecules |
Statistics of the Clinical Trials of the Found Kinase Inibitors from clinicaltrials.gov (06-17-2024) |
Clinical Trials from clinicaltrials.gov (06-17-2024) |
Fusion Gene | Kinase Inhibitor | NCT ID | Study Status | Phases | Disease | # Enrolment | Date |