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Center for Computational Systems Medicine
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Kinase Fusion Gene Summary

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Kinase Fusion Gene Sample Information

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Kinase Fusion ORF Analysis

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Kinase Fusion Amino Acid Sequences

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Multiple Sequence Alignment of All Fusion Protein Isoforms

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Kinase Fusion Protein Functional Features

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Kinase Fusion Protein Structures

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Comparison of Fusion Protein Isoforms

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Comparison of Fusion Protein Sequences/Structures with Known Sequences/Structures from PDB

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pLDDT Scores and Difference Analysis of pLDDT Scores Between the Active Sites (Best) and Non-Active Sites.

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Ramachandran Plot of Kinase Fusion Protein Structure

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Potential Active Site Information

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Virtual Screening Results

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Kinase-Substrate Information

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Related Drugs with This Kinase Fusion Protein

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Related Disease with This Kinase Fusion Protein

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Clinical Trials of the Found Drugs/Small Molecules

Kinase Fusion Gene:ZNF587B_SRC

Kinase Fusion Protein Summary

check button Kinase Fusion gene summary
Kinase Fusion partner gene informationKinase Fusion gene name: ZNF587B_SRC
KinaseFusionDB ID: KFG7293
FusionGDB2.0 ID: KFG7293
HgeneTgene
Gene symbol

ZNF587B

SRC

Gene ID

100293516

6714

Gene namezinc finger protein 587BSRC proto-oncogene, non-receptor tyrosine kinase
Synonyms-ASV|SRC1|THC6|c-SRC|p60-Src
Cytomap

19q13.43

20q11.23

Type of geneprotein-codingprotein-coding
Descriptionzinc finger protein 587Bproto-oncogene tyrosine-protein kinase Srcproto-oncogene c-Srcprotooncogene SRC, Rous sarcomatyrosine kinase pp60c-srctyrosine-protein kinase SRC-1v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
Modification date2024041120240411
UniProtAcc

E7ETH6

Q9C0H9

Ensembl transtripts involved in fusion geneENST idsENST00000316462, ENST00000442832, 
ENST00000594901, 		ENST00000477066, 
ENST00000358208, ENST00000360723, 
ENST00000373558, ENST00000373567, 
ENST00000373578, ENST00000445403, 
Context (manual curation of fusion genes in KinaseFusionDB)

PubMed: ZNF587B [Title/Abstract] AND SRC [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)ZNF587B(58331313)-SRC(36028518), # samples:2
check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneSRC

GO:0018108

peptidyl-tyrosine phosphorylation

22732588

TgeneSRC

GO:0018108

peptidyl-tyrosine phosphorylation

12051764

TgeneSRC

GO:0034139

regulation of toll-like receptor 3 signaling pathway

37158982

TgeneSRC

GO:0035306

positive regulation of dephosphorylation

23159740

TgeneSRC

GO:0035556

intracellular signal transduction

11606584|15248232

TgeneSRC

GO:0045747

positive regulation of Notch signaling pathway

25731159

TgeneSRC

GO:0046777

protein autophosphorylation

16441665

TgeneSRC

GO:0060576

intestinal epithelial cell development

25731159

TgeneSRC

GO:0070102

interleukin-6-mediated signaling pathway

25731159

TgeneSRC

GO:0071902

positive regulation of protein serine/threonine kinase activity

19059439

TgeneSRC

GO:1904263

positive regulation of TORC1 signaling

35927303


check buttonKinase Fusion gene breakpoints across ZNF587B (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonKinase Fusion gene breakpoints across SRC (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.


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Kinase Fusion Gene Sample Information

check buttonKinase Fusion gene information.
check button Kinase Fusion gene information from four resources (ChiTars 5.0, ChimerDB 4.0, COSMIC, and CCLE)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceSampleHgeneHchrHbpTgeneTchrTbp
ChimerDB4TCGA-AO-A03V-01AZNF587Bchr19

58331313

SRCchr20

36028518

ChimerDB4TCGA-AO-A03V-01AZNF587Bchr19

58331917

SRCchr20

36028518



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Kinase Fusion ORF Analysis


check buttonKinase Fusion information from ORFfinder translation from full-length transcript sequence from KinaseFusionDB.
HenstTenstHgeneHchrHbpTgeneTchrTbpSeq length
(transcript)		Seq length
(amino acids)

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Kinase Fusion Amino Acid Sequences


check button For individual full-length fusion transcript sequence from KinaseFusionDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>Henst_Tenst_Hgene_Hchr_Hbp_Tgene_Tchr_Tbp_length(fusion AA)_AAseq

Multiple Sequence Alignment of All Fusion Protein Isoforms



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Kinase Fusion Protein Functional Features


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/:58331313/:36028518)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ZNF587B

E7ETH6

SRC

Q9C0H9

FUNCTION: May be involved in transcriptional regulation. {ECO:0000305}.FUNCTION: Acts as a negative regulator of SRC by activating CSK which inhibits SRC activity and downstream signaling, leading to impaired cell spreading and migration. Regulates dendritic spine morphology. Involved in calcium-dependent exocytosis. May play a role in neurotransmitter release or synapse maintenance. {ECO:0000269|PubMed:14657239, ECO:0000269|PubMed:17525734, ECO:0000269|PubMed:19146815}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

* Minus value of BPloci means that the break pointn is located before the CDS.

check button - Retained domain in the 5'-partner of fusion protein (protein functional feature from UniProt).
PartnerHgeneeneHbpTgeneeneTbpENSTBPexonTotalExonProtein feature lociBPlociTotalLenFeatureNote


check button - Retained domain in the 3'-partner of fusion protein (protein functional feature from UniProt).
PartnerHgeneeneHbpTgeneeneTbpENSTBPexonTotalExonProtein feature lociBPlociTotalLenFeatureNote


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Kinase-Substrate Information of ZNF587B_SRC


check button Phosphorylation target of the kinase
(phosphosite, 03-17-2024)
KinaseKinase UniProt AccKinase speciesSubstrateSubstrate UniProt AccSubstrate phosphorylated residuesSubstrate phosphorylated sites (+/-7AA)Domain
SRCP12931humanPTENP60484Y155AQEALDFyGEVRTRD
SRCP12931humanGJA1P17302Y265kDCGsQkyAyFNGCs
SRCP12931humanSPTAN1Q13813Y1073MkQVEELyHsLLELG
SRCP12931humanYAP1P46937Y407sGLsMsSySVPRtPD
SRCP12931humanTIMP2P16035Y90EKDIEFIyTAPSSAVTIMP
SRCP12931humanFLT4P35916Y830PLEEQCEyLSyDASQ
SRCP12931humanTHRAP3Q9Y2W1Y344AAsGGAAytKRyLEETHRAP3_BCLAF1
SRCP12931humanCDCP1Q9H5V8Y734KDNDsHVyAVIEDTM
SRCP12931humanHNF4AP41235Y288IDDNEyAyLKAIIFFHormone_recep
SRCP12931humanEYA3Q99504S138SGLIQTPsPSQHSVL
SRCP12931humanSHC1P29353-3Y194EEPPDHQyyNDFPGK
SRCP12931humanEYA3Q99504Y426YRKVREIyDKHkSNV
SRCP12931humanHDAC3O15379Y331PySEyFEyFAPDFTL
SRCP12931humanKIF11P52732Y211VHNkDEVyQILEkGAKinesin
SRCP12931humanGBF1Q92538Y516VENPKMPyEMKEMALSec7_N
SRCP12931humanATG9AQ7Z3C6Y8MAQFDTEyQRLEAsy
SRCP12931humanGTF2IP78347-2Y248EESEDPDyyQyNIQG
SRCP12931humanTRPV1Q8NER1Y200ASYtDSYyKGQTALHAnk_2
SRCP12931humanBCKDKO14874Y246RRLCEHkyGNAPRVR
SRCP12931humanPLCG2P16885Y753ERDINSLyDVsRMyV
SRCP12931humanCDH2P19022Y884SSGGEQDyDyLNDWGCADH_Y-type_LIR
SRCP12931humanBDKRB2P30411Y347RKKSWEVyQGVCQKG
SRCP12931humanWNK4Q96J92Y1164KKEIEDLySRLGKQP
SRCP12931humanGIT1Q9Y2X7Y284EELAMDVyDEVDRREGIT_SHD
SRCP12931humanGAB1Q13480Y242FFQQQMIyDsPPSRA
SRCP12931humanAKAP8O43823Y53TTGATySyGPASWEA
SRCP12931humanCHN2P52757Y21VSSDAEEyQPPIWKS
SRCP12931humanHNRNPKP61978Y234PNFyDETyDyGGFTM
SRCP12931humanACLYP53396Y682sRtTDGVyEGVAIGGLigase_CoA
SRCP12931humanSFPQP23246Y691GPGtPAGyGrGrEEy
SRCP12931humanDVL2O14641Y18VGEtKVIyHLDEEETDIX
SRCP12931humanGTF2IP78347Y248EESEDPDyyQYNIQA
SRCP12931humanHLA-AP04439Y344sDRkGGsytQAAssDMHC_I_C
SRCP12931humanEPS8Q12929Y485EHssVsEyHPADGyA
SRCP12931humanDAPK1P53355Y490HCAAWHGyySVAKALAnk_2
SRCP12931humanRGS16O15492Y177RFLkSPAyRDLAAQARGS
SRCP12931humanZC3H4Q9UPT8Y247SRGRGRGyRGRGSRG
SRCP12931humanPAG1Q9NWQ8Y317EEEIsAMyssVNKPGPAG
SRCP12931humanDDR2Q16832Y736FGMSRNLysGDyyRIPK_Tyr_Ser-Thr
SRCP12931humanNR1H4Q96RI1Y77QISSSSYySNLGFYP
SRCP12931humanSF3B2Q13435Y379VtEEPEIyEPNFIFF
SRCP12931humanBCLAF1Q9NYF8Y80YRGrGrGyyQGGGGr
SRCP12931humanPDPK1O15530Y376DEDCyGNyDNLLSQF
SRCP12931humanFHOD1Q9Y613Y99REMLEGFyEEISKGRFormin_GBD_N
SRCP12931humanSHC1P29353-3Y272ELFDDPSyVNVQNLD
SRCP12931humanUGT2B7P16662Y438RVINDPSyKENVMKLUDPGT
SRCP12931humanBAIAP2L1Q9UHR4Y156GsRNALkyEHKEIEyIMD
SRCP12931humanEYA3Q99504Y77QMySAKPyAHILSVP
SRCP12931humanGBF1Q92538Y1374PsPLINQysLTVGLD
SRCP12931humanGLRBP48167Y435RDFELSNyDCYGkPINeur_chan_memb
SRCP12931humanGRIK2Q13002Y590RFSPYEWyNPHPCNPLig_chan
SRCP12931humanL1CAMP32004Y1176kDEtFGEyRSLEsDNBravo_FIGEY
SRCP12931humanHRASP01112Y64DTAGQEEySAMRDQYRas
SRCP12931humanNEDD4P46934-4Y332RRGsLQAyTFEEQPT
SRCP12931humanPTPN6P29350Y564sKHkEDVyENLHTkN
SRCP12931humanPARP1P09874Y992LYNEYIVyDIAQVNLPARP
SRCP12931humanPTK2Q05397Y925DRsNDkVyENVtGLVFocal_AT
SRCP12931humanCDC25AP30304Y59LQGLGSDyEQPLEVK
SRCP12931humanANXA2P07355Y24HstPPsAyGsVkAyt
SRCP12931humanUSP2O75604S207ENYGRKGsASQVPSQ
SRCP12931humanCD46P15529-4Y354kADGGAEyAtyQtkS
SRCP12931humanNOS2P35228Y1055LPGKPKVyVQDILRQNAD_binding_1
SRCP12931humanTLR3O15455Y759EQFEYAAyIIHAYKDTIR
SRCP12931humanITGB7P26010Y753YRLSVEIyDRREySRIntegrin_b_cyt
SRCP12931humanBCLAF1Q9NYF8Y408DtEEtEDyRQFRksVTHRAP3_BCLAF1
SRCP12931humanPTENP60484Y174TIPSQRRyVyyysyL
SRCP12931humanMYH9P35579Y158yAITDTAyRsMMQDrMyosin_head
SRCP12931humanEYA3Q99504Y508IFPIENIySATKIGk
SRCP12931humanPRKD2Q9BZL6Y87kFPECGFyGLYDkIL
SRCP12931humanPELP1Q8IZL8Y920EEEDEEEyFEEEEEE
SRCP12931humanSRRTQ9BXP5Y92DEHSSDPyHSGYEMP
SRCP12931humanAGO2Q9UKV8Y529LPGKtPVyAEVkRVGPiwi
SRCP12931humanRMDN3Q96TC7Y176DAESEGGytTANAEs
SRCP12931humanENGP17813Y612LLTAALWyIySHTRS
SRCP12931humanEYA3Q99504Y90VPVSETAyPGQTQyQ
SRCP12931humanCDH1P12830Y754DtRDNVyyyDEEGGG
SRCP12931humanSPTAN1Q13813Y1176AVQQQEVyGMMPRDE
SRCP12931humanSTAP2Q9UGK3Y250PFLLDEDyEKVLGyV
SRCP12931humanFCRL3Q96P31Y722EEDDEENyENVPRVL
SRCP12931humanTNK2Q07912Y860KVsstHyyLLPERPs
SRCP12931humanHNRNPKP61978Y230QPyDPNFyDETyDyG
SRCP12931humanFCRL3Q96P31Y662PGDSNPIySQIWSIQ
SRCP12931humanBAIAP2L1Q9UHR4Y439VVIPPPDyLECLsMG
SRCP12931humanEYA3Q99504Y208TILGQNQyQACYPSS
SRCP12931humanEGFRP00533Y764kEILDEAyVMAsVDNPK_Tyr_Ser-Thr
SRCP12931humanPLSCR1O15162Y69PVPNQPVyNQPVyNQ
SRCP12931humanEYA3Q99504S157GLTTSQPsPAHYSYP
SRCP12931humanHLA-BP01889Y344SGGkGGsySQAACsDMHC_I_C
SRCP12931humanTHOC5Q13769Y225EIEVKKEyLSSLQPRFmiP_Thoc5
SRCP12931humanCDH2P19022Y886GGEQDyDyLNDWGPRCADH_Y-type_LIR
SRCP12931humanANXA1P04083Y21IENEEQEyVQtVkss
SRCP12931humanBCLAF1Q9NYF8Y81RGrGrGyyQGGGGry
SRCP12931humanPPP2CAP67775Y127SRQITQVyGFYDECLMetallophos
SRCP12931humanCASP8Q14790Y380tDsEEQPyLEMDLSsPeptidase_C14
SRCP12931humanKCNJ1P48048Y337SKTKEGKyRVDFHNFIRK_C
SRCP12931humanNRASP01111Y32QNHFVDEyDPTIEDsRas
SRCP12931humanNCKIPSDQ9NZQ3Y227STSLDTLyTSSSPSE
SRCP12931humanSDCBPO00560Y46IPHDGNLyPRLyPEL
SRCP12931humanFBXO5Q9UKT4Y142ALETSRLyEDsGYSs
SRCP12931humanHSP90AB1P08238Y301DDItQEEyGEFyksLHSP90
SRCP12931humanWBP2Q969T9Y231AEAAASAyyNPGNPH
SRCP12931humanUSP2O75604S225SRVPEIIsPTYRPIG
SRCP12931humanBDKRB2P30411Y177GVRWAKLysLVIWGCTM; 7tm_1
SRCP12931humanCTTNQ14247Y470AyATEAVyESAEAPG
SRCP12931humanARAFP10398Y302GyRDsGyyWEVPPSE
SRCP12931humanDAPK1P53355Y491CAAWHGyySVAKALCAnk_2
SRCP12931humanTRIP10Q15642-3Y471ESQDTPIyTEFDEDF
SRCP12931humanEYA3Q99504Y96AyPGQTQyQTLQQTQ
SRCP12931humanGBF1Q92538Y378AsVHDMDyVNPRGVR
SRCP12931humanKIF11P52732Y231AAtLMNAyssRSHSVKinesin
SRCP12931humanBCLAF1Q9NYF8Y150SSRSSsPysksPVsKTHRAP3_BCLAF1
SRCP12931humanARHGDIAP52565Y27EDEHsVNykPPAQKsRho_GDI
SRCP12931humanYAP1P46937-3Y341PFLNSGTyHSRDEST
SRCP12931humanHSP90AA1P07900Y197LkEDQtEyLEErRIkHSP90
SRCP12931humanFHITP49789Y114FHRNDsIyEELQKHD
SRCP12931humanATG9AQ7Z3C6Y15yQRLEAsysDsPPGE
SRCP12931humanSIRT2Q8IXJ6Y104RSPStGLyDNLEKYHSIR2
SRCP12931humanLPIN1Q14693Y795FPNTEPFyAAFGNRPLNS2
SRCP12931humanSLC6A4P31645Y47SGQISNGysAVPSPG5HT_transport_N
SRCP12931humanFCRL3Q96P31Y692HEELTVLySELKKTH
SRCP12931humanFXNQ16595Y118EDLADKPyTFEDYDVFrataxin_Cyay
SRCP12931humanSHC1P29353Y350EPPDHQyyNDFPGKE
SRCP12931humanG6PDP11413Y428DLtyGNRyKNVkLPDG6PD_C
SRCP12931humanPRKCDQ05655Y313ssEPVGIyQGFEKkT
SRCP12931humanPTK2Q05397Y577yMEDstyyKAsKGKLPK_Tyr_Ser-Thr
SRCP12931humanSTAT5AP42229Y694LAkAVDGyVkPQIkQ
SRCP12931humanBCLAF1Q9NYF8Y93GryHrGGyrPVWNRR
SRCP12931humanPFN1P07737Y129GLINkkCyEMAsHLRProfilin
SRCP12931humanSRRTQ9BXP5Y798tPQGLMPyGQPRPPIARS2
SRCP12931humanFERMT2Q96AC1Y193skTMTPtyDAHDGsP
SRCP12931humanPRKCDQ05655Y334MQDNsGtyGkIWEGs
SRCP12931humanTUBB3Q13509Y340IQskNssyFVEWIPNTubulin_C
SRCP12931humanFUBP1Q96AE4Y268FREVRNEyGsRIGGN
SRCP12931humanCASP9P55211Y251LQFPGAVyGTDGCPVPeptidase_C14
SRCP12931humanMPZL1O95297Y263NksEsVVyADIRKN_
SRCP12931humanRBM10P98175-2Y434SEEPPVDySYYQQDE
SRCP12931humanHNRNPKP61978Y236FyDETyDyGGFTMMF
SRCP12931humanTHRAP3Q9Y2W1Y68ErNHPrVyQNrDFrG
SRCP12931humanCD93Q9NPY3Y644sRAMENQySPTPGTD
SRCP12931humanZC3H4Q9UPT8Y1218PTDRYNSyNRPRPKA
SRCP12931humanDOK1Q99704Y362DPKEDPIyDEPEGLA
SRCP12931humanEPS8Q12929Y774CPEGARVysQITVQkSAM_3
SRCP12931humanRPS6KB2Q9UBS0Y45GLEPVGHyEEVELTE
SRCP12931humanPRKAA2P54646Y179tsCGsPNyAAPEVISPkinase
SRCP12931humanRAPGEF1Q13905Y504APIPSVPyAPFAAIL
SRCP12931humanAP2B1P63010Y737THRQGHIyMEMNFTNAlpha_adaptinC2
SRCP12931humanVIL1P09327Y256LKAALKLyHVsDsEG
SRCP12931humanEYA3Q99504S438SNVGGLLsPQRKEAL
SRCP12931humanWBP2Q969T9Y192MMDGAMGyVQPPPPP
SRCP12931humanNEDD4P46934-4Y43ILGASDPyVRVTLYDC2
SRCP12931humanLPIN1Q14693Y413DPEVAALyFPKNGDP
SRCP12931humanPTPRJQ12913Y1320NtTAMtIyENLAPVT
SRCP12931humanTP73O15350Y28SLEPDStyFDLPQSS
SRCP12931humanPTK2Q05397Y1007kMKLAQQyVMTSLQQFocal_AT
SRCP12931humanPTENP60484Y46AERLEGVyRNNIDDV
SRCP12931humanGSK3BP49841Y216RGEPNVsyICsRyyRPkinase
SRCP12931humanLMNAP02545Y45LNDrLAVyIDrVRsLFilament
SRCP12931humanDVL2O14641Y275VTLNMEKyNFLGISIPDZ
SRCP12931humanZAP70P43403Y319tsVyEsPysDPEELk
SRCP12931humanHK2P52789Y686GTGSNACyMEEMRNVHexokinase_2
SRCP12931humanCDH1P12830Y797tLMsVPRyLPRPANP
SRCP12931humanEGFRP00533Y1092tFLPVPEyINQsVPk
SRCP12931humanCACNA1CQ13936Y2217ELQDSRVyVSSL___
SRCP12931humanPTPRJQ12913Y1311DSkVDLIyQNtTAMt
SRCP12931humanETS1P14921Y283sLQRVPsyDsFDsEDEts1_N_flank
SRCP12931humanDGKAP23743Y335ILPPSSIyPSVLASG
SRCP12931humanCTTNQ14247Y334VTQVssAyQktVPVE
SRCP12931humanFLOT1O75955Y56NVkSEkVyTRHGVPIBand_7
SRCP12931humanMDM2Q00987Y281EVyQVtVyQAGEsDt
SRCP12931humanPRKD1Q15139Y502TTANVVYyVGENVVNPH
SRCP12931humanGAB1Q13480Y373AsDtDssyCIPTAGM
SRCP12931humanZC3H4Q9UPT8Y158GHRKyREysPPyAPs
SRCP12931humanFLT4P35916Y1063FGLARDIykDPDyVRPK_Tyr_Ser-Thr
SRCP12931humanSHC3Q92529-2Y218GDGSDHPyyNSIPSK
SRCP12931humanAKAP8O43823Y154RPsySyDyEFDLGSD
SRCP12931humanSF3B2Q13435Y592TIHGDLyyEGKEFETDUF382
SRCP12931humanNEDD4P46934-4Y647RVAGMAVyHGKLLDGHECT
SRCP12931humanSHC1P29353Y349EEPPDHQyyNDFPGK
SRCP12931humanELMO1Q92556Y724PsNyDFVyDCN____
SRCP12931humanEMDP50402Y74tRGDADMyDLPkkED
SRCP12931humanTGFBR2P37173Y284KIFPYEEyASWKTEkPK_Tyr_Ser-Thr
SRCP12931humanCDH2P19022Y852NDPTAPPyDSLLVFDCADH_Y-type_LIR
SRCP12931humanVIL1P09327Y60KTASSLSyDIHyWIGGelsolin
SRCP12931humanGRK2P25098Y86ARPLVEFyEEIKKyERGS
SRCP12931humanNOXA1Q86UR1Y110RGHAAIDyTQLGLRF
SRCP12931humanCDKN1BP46527Y88kGsLPEFyyRPPRPP
SRCP12931humanCTNNB1P35222Y86VADIDGQyAMTRAQR
SRCP12931humanG6PDP11413Y249GTEGRGGyFDEFGIIG6PD_C
SRCP12931humanGRIN2AQ12879Y1267PATGEQVyQQDWAQNNMDAR2_C
SRCP12931humanHIPK2Q9H2X6Y361SkAVCstyLQsRYyRPkinase
SRCP12931humanHDAC3O15379Y325AISEELPySEyFEyF
SRCP12931humanPKP3Q9Y446Y195PGGLDDRysLVsEQL
SRCP12931humanRIPK1Q13546Y384kLQDEANyHLyGsRM
SRCP12931humanAFAP1Q8N556Y93TSSLPEGyyEEAVPL
SRCP12931humanSDHAP31040Y215SLRYDTSyFVEYFALFAD_binding_2
SRCP12931humanTERTO14746Y707QDPPPELyFVKVDVT
SRCP12931humanAKAP8O43823Y539IVkMLEkyLKGEDPFAKAP95
SRCP12931humanSHC3Q92529-2Y256FAGKEQTyyQGRHLG
SRCP12931humanGIT1Q9Y2X7Y321FLPVNPEySATRNQG
SRCP12931humanFLT4P35916Y1333ARGGQVFyNSEyGEL
SRCP12931humanPTENP60484Y240RREDKFMyFEFPQPLPTEN_C2
SRCP12931humanNOS2P35228Y151IEFVNQYyGSFKEAKNO_synthase
SRCP12931humanRPS6KA3P51812Y483IItLkDVyDDGKyVYPkinase
SRCP12931humanMYLKQ15746Y464QEGsIEVyEDAGsHyI-set
SRCP12931humanPPP2CAP67775Y307VTRRtPDyFl_____
SRCP12931humanRAF1P04049Y341GQRDssyyWEIEASE
SRCP12931humanSNCAP37840Y125VDPDNEAyEMPsEEGSynuclein
SRCP12931humanCORO7P57737Y758GDTRVFLyELLPEsP
SRCP12931humanEYA3Q99504Y108QTQPyAVyPQATQTy
SRCP12931humanPTK2Q05397Y898LSsPADSyNEGVKLQ
SRCP12931humanPAK2Q13177S141tVkQKyLsFtPPEkd
SRCP12931humanF11RQ9Y624Y280tSsKkVIysQPsARs
SRCP12931humanFHL1Q13642-1Y149FPkGEDFyCVTCHETLIM
SRCP12931humanLPPQ93052Y301GRyyEGyyAAGPGyG
SRCP12931humanGBF1Q92538Y877QDILEDMyHAIKNEESec7
SRCP12931humanPPP2CAP67775Y284ELDDTLkySFLQFDP
SRCP12931humanTNK2Q07912Y859KKVsstHyyLLPERP
SRCP12931humanGSNP06396Y651ALGGkAAyRTsPRLK
SRCP12931humanGBF1Q92538Y1568VRMQALTyLQRALLV
SRCP12931humanPIP5K1CO60331Y649TDERSWVysPLHYSA
SRCP12931humanGRIN2AQ12879Y1387GRCPSDPyKHSLPSQNMDAR2_C
SRCP12931humanCDKN1BP46527Y74HkPLEGkyEWQEVEkCDI
SRCP12931humanSRRTQ9BXP5Y836YGAGrGNyDAFrGQGARS2
SRCP12931humanSDC2P34741Y179RKkDEGSyDLGErkPSyndecan
SRCP12931humanDUSP12Q9UNI6Y179VDTSSAIyKQYRLQK
SRCP12931humanFLT4P35916Y853HLGRVLGyGAFGKVVPK_Tyr_Ser-Thr
SRCP12931humanCD93Q9NPY3Y628PQNAADsysWVPERA
SRCP12931humanKCNA3P22001Y499EGEEQSQyMHVGsCQ
SRCP12931humanGBF1Q92538Y899TGLVRENyVWNVLLH
SRCP12931humanSH3PXD2BA1X283Y508DMSASAGyEEIsDPD
SRCP12931humanIQGAP1P46940Y1510LVkLQQtyAALNskARasGAP_C
SRCP12931humanWNK4Q96J92Y1113PSPVWMNySySSLCL
SRCP12931humanCHKAP35790Y333LMLIDFEySSYNYRGCholine_kinase
SRCP12931humanGAB1Q13480Y317PPtPGNtyQIPRTFP
SRCP12931humanDAAM1Q9Y4D1Y652LERTFSAyQRQQDFFFH2
SRCP12931humanKLF16Q9BXK1Y10AAVACVDyFAADVLM
SRCP12931humanSTAT3P40763Y705DPGsAAPyLktKFIC
SRCP12931humanCBLP22681Y774sENEDDGyDVPKPPV
SRCP12931humanIKBKBO14920Y188sFVGTLQyLAPELLEPkinase
SRCP12931humanPTK2Q05397Y407IIDEEDtytMPSTRD
SRCP12931humanMDM2Q00987Y302PEISLADyWKCtsCNzf-RanBP
SRCP12931humanLRP1Q07954Y4473VEIGNPTyKMYEGGE
SRCP12931humanOCLNQ16625Y398KRtEQDHyEtDyttG
SRCP12931humanARHGEF2Q92974Y198IDEAEVIySELMSDF
SRCP12931humanEGFRP00533Y1110GsVQNPVyHNQPLNP
SRCP12931humanACLYP53396Y252EAyPEEAyIADLDAkCitrate_bind
SRCP12931humanWWOXQ9NZC7Y33TTkDGWVyYANHTEEWW
SRCP12931humanNPHS1O60500Y1176MAFPGHLyDEVERTY
SRCP12931humanGRIN1Q05586Y837LIFIEIAyKRHKDARCaM_bdg_C0
SRCP12931humanGSNP06396-3Y438GDSYIILyNYRHGGRGelsolin
SRCP12931humanFLT4P35916Y1337QVFyNSEyGELSEPS
SRCP12931humanCNKSR1Q969H4Y665KEQNRELySEGLGAW
SRCP12931humanTNK2Q07912Y827SFASDPkyAtPQVIQInhibitor_Mig-6
SRCP12931humanRACK1P63244Y246LCFSPNryWLCAATGWD40
SRCP12931humanHNF4AP41235Y23SAALDPAyTTLEFEN
SRCP12931humanPEAK1Q9H792Y635IVINPNAyDNLAIyK
SRCP12931humanDVL2O14641Y295ERGDGGIyIGSIMkGPDZ
SRCP12931humanTP53P04637Y220rHsVVVPyEPPEVGSP53
SRCP12931humanCORO7P57737Y288GERQLYCyEVVPQQP
SRCP12931humanVIL1P09327Y64SLSyDIHyWIGQDSSGelsolin
SRCP12931humanRHOUQ7L0Q8Y254SkSWWKKyCCFV___
SRCP12931humanBAIAP2L1Q9UHR4Y163yEHKEIEyVEtVTSRIMD
SRCP12931humanCDK4P11802Y17AEIGVGAyGTVYkARPkinase
SRCP12931humanPROM1O43490Y828RMDsEDVyDDVEtIP
SRCP12931humanCDCP1Q9H5V8Y762LQPEVDTyRPFQGTM
SRCP12931humanACLYP53396Y1006PAtPLLDyALEVEkICitrate_synt
SRCP12931humanKDRP35968Y1175AQQDGKDyIVLPISE
SRCP12931humanEYA3Q99504Y237TTLAATTyQSEKPSV
SRCP12931humanAFAP1Q8N556Y125MSSSYESyDEEEEDG
SRCP12931humanNCKIPSDQ9NZQ3Y161LGADGGLyQIPLPSS
SRCP12931humanABL1P00519-2Y488EGCPEKVyELMRACWPK_Tyr_Ser-Thr
SRCP12931humanATXN2LQ8WWM7Y744VPGQQGKyRGAKGSL
SRCP12931humanRPS6KA3P51812Y707KGAMAAtysALNRNQ
SRCP12931humanAKAP8O43823Y146CLPEHNPyRPsySyD
SRCP12931humanARHGAP5Q13017Y1109kGysDEIyVVPDDsQRhoGAP_pG1_pG2
SRCP12931humanAKAP8O43823Y170NGsFGGQySECRDPA
SRCP12931humanCCDC88AQ3V6T2Y1799QSkDsNPyAtLPRAS
SRCP12931humanSTAP2Q9UGK3Y22GVLPSHYyESFLEKKPH
SRCP12931humanCNKSR1Q969H4Y519PPREEDCySETEAED
SRCP12931humanPDHA1P08559Y289MELQTYRyHGHsMsDE1_dh
SRCP12931humanKRT19P08727Y391LEGQEDHyNNLsAsk
SRCP12931humanOCLNQ16625Y402QDHyEtDyttGGEsC
SRCP12931humanKCNB1Q14721Y128YWGIDEIyLESCCQABTB_2
SRCP12931humanPTK2Q05397Y742HMVQTNHyQVSGYPG
SRCP12931humanSOCS1O15524Y80LLDACGFyWGPLSVHSH2
SRCP12931humanRHOAP61586Y34kDQFPEVyVPTVFENRas
SRCP12931humanYAP1P46937-3Y394QQNRFPDyLEAIPGT
SRCP12931humanCYP19A1P11511Y361KVMENFIyESMRYQPp450
SRCP12931humanPDPK1O15530Y373sEDDEDCyGNyDNLL
SRCP12931humanKCNA3P22001Y187FSEEIRFyQLGEEAMBTB_2
SRCP12931humanSRCP12931Y93VTTFVALyDyEsRTESH3_1
SRCP12931humanPRKD1Q15139Y432KEGWMVHyTSKDTLRPH
SRCP12931humanMAPTP10636-8Y18MEDHAGtyGLGDRKD
SRCP12931humanDLG4P78352Y523REDSVLSyETVTQME
SRCP12931humanAGO2Q9UKV8Y393AsFNtDPyVREFGIMArgoL2
SRCP12931humanGAB1Q13480Y259AsVDssLyNLPRSys
SRCP12931humanEMDP50402Y95kGyNDDyyEEsyFtT
SRCP12931humanGLO1Q04760Y136GIAVPDVysACkRFEGlyoxalase
SRCP12931humanBAIAP2L1Q9UHR4Y37LINLGKNyEkAVNAMIMD
SRCP12931humanDDR2Q16832Y740RNLysGDyyRIQGRAPK_Tyr_Ser-Thr
SRCP12931humanHCRTR1O43613Y358SAANPIIyNFLSGKF7tm_1; TM
SRCP12931humanFCRL3Q96P31Y650PMELEPMySNVNPGD
SRCP12931humanSLC25A4P12235Y195RAAyFGVyDtAkGMLTM; Mito_carr
SRCP12931humanBAIAP2L1Q9UHR4Y274SNVVRKDyDtLskCs
SRCP12931humanCASP8Q14790-4Y397TDSEEQPyLEMDLSSPeptidase_C14
SRCP12931humanPTENP60484Y377sDNEPDHyRYsDttD
SRCP12931humanGAPDHP04406Y42DPFIDLNyMVyMFQyGp_dh_N
SRCP12931humanHRASP01112Y96SFEDIHQyREQIKRVRas
SRCP12931humanGSNP06396Y465VPVDPATyGQFYGGDGelsolin
SRCP12931humanGRK2P25098Y13AVLADVSyLMAMEkS
SRCP12931humanGRIN2AQ12879Y1325RLLEGNFyGSLFSVPNMDAR2_C
SRCP12931humanSTAT3P40763Y68LGEIDQQySRFLQESSTAT_int
SRCP12931humanCDCP1Q9H5V8Y743VIEDTMVyGHLLQDS
SRCP12931humanSLC6A4P31645Y142MELALGQyHRNGCIsSNF
SRCP12931humanEYA3Q99504S225GVTGQTNsDAESTTL
SRCP12931humanHDAC3O15379Y328EELPySEyFEyFAPD
SRCP12931humanCAV1Q03135Y14VDsEGHLytVPIREQ
SRCP12931humanCHKAP35790Y197RSLGPkLyGIFPQGRCholine_kinase
SRCP12931humanMUC1P15941Y1229sstDRsPyEKVsAGN
SRCP12931humanPDCD6IPQ8WUM4Y319KkDNDFIyHDrVPDLBRO1
SRCP12931humanSHC1P29353Y427ELFDDPsyVNVQNLD
SRCP12931humanCCR7P32248Y155LCIsIDRyVAIVQAV7tm_1
SRCP12931humanKHSRPQ92945Y583WAAYYSHyYQQPPGP
SRCP12931humanITGB7P26010Y758EIyDRREySRFEkEQIntegrin_b_cyt
SRCP12931humanHNRNPKP61978Y458LQNsVkQySGkFF__
SRCP12931humanAURKAO14965Y148kGkFGNVyLAREKQSPkinase
SRCP12931humanSTING1Q86WV6Y245RVysNSIyELLENGQTMEM173
SRCP12931humanKNSTRNQ9Y448Y87TSVVKtVySLQPPSA
SRCP12931humanEZRP15311Y478PPPPPPVyEPVsyHV
SRCP12931humanGTF2IP78347Y249ESEDPDyyQYNIQAG
SRCP12931humanPRKD1Q15139Y95KFPECGFyGMYDKIL
SRCP12931humanLPPQ93052Y244APssGQIyGsGPQGy
SRCP12931humanTIMP2P16035Y165RCPMIPCyISSPDECTIMP
SRCP12931humanSH3GLB1Q9Y371Y80ARIEEFVyEkLDRKABAR
SRCP12931humanAFAP1Q8N556Y453PEALHyDyIDVEMSA
SRCP12931humanGRB10Q13322Y67NASLESLySACSMQS
SRCP12931humanTRIP6Q15654Y55PLPsEQCyQAPGGPE
SRCP12931humanEGFRP00533Y1016DVVDADEyLIPQQGF
SRCP12931humanRACK1P63244Y52LtrDEtNyGIPQRAL
SRCP12931humanEPS8Q12929Y525NRHIDRNyEPLKtQP
SRCP12931humanPANX1Q96RD7Y199KYPIVEQyLkTkkNSInnexin
SRCP12931humanFLOT1O75955Y149MGISVVSyTLkDIHDBand_7
SRCP12931humanG6PDP11413Y507GFQyEGtykWVNPHkG6PD_C
SRCP12931humanNFE2L2Q16236Y576RDEDGkPysPSEYSL
SRCP12931humanMAPRE1Q15691Y247QRIVDILyATDEGFVEB1
SRCP12931humanSRCP12931Y530FTstEPQyQPGENL_
SRCP12931humanCDH5P33151Y731PyDTLHIyGyEGSESCADH_Y-type_LIR
SRCP12931humanELMO1Q92556Y720IPKEPsNyDFVyDCN
SRCP12931humanAKAP8O43823Y51SVTTGATySyGPASW
SRCP12931humanPLCG2P16885Y759LyDVsRMyVDPsEIN
SRCP12931humanRPS6KA3P51812Y529TITKTVEyLHAQGVVPkinase
SRCP12931humanKRASP01116Y32QNHFVDEyDPTIEDsRas
SRCP12931humanRACK1P63244Y228LNEGkHLyTLDGGDIWD40
SRCP12931humanSDCBPO00560Y4____MsLyPsLEDLk
SRCP12931humanCBLCQ9ULV8Y341SEEQLQLyWAMDSTF
SRCP12931humanNPHS1O60500Y1193SGAWGPLyDEVQMGP
SRCP12931humanGSNP06396Y409TDGLGLsyLSSHIAN
SRCP12931humanSFPQP23246Y597RRQREESySRMGyMD
SRCP12931humanTFGQ92734Y33IHNEDITyDELVLMMPB1
SRCP12931humanEYA3Q99504Y72NDyTSQMySAKPyAH
SRCP12931humanGJA1P17302Y247VKGksDPyHAtsGAL
SRCP12931humanRPS6KA3P51812Y580GLLMtPCytANFVAPPkinase
SRCP12931humanPROM1O43490Y852GYHkDHVyGIHNPVM
SRCP12931humanGTF2IP78347-2Y611KPELVISyLPPGMAS
SRCP12931humanERBB2P04626Y877LDIDEtEyHADGGkVPK_Tyr_Ser-Thr
SRCP12931humanPTK2Q05397Y397sVsEtDDyAEIIDEE
SRCP12931humanGRIN2AQ12879Y1292RISRQHsyDNIVDKPNMDAR2_C
SRCP12931humanPAK3O75914S154VNNQKYMsFTSGDKS
SRCP12931humanCDH2P19022Y820PIHAEPQyPVRsAAP
SRCP12931humanEGFRP00533Y869LGAEEkEyHAEGGkVPK_Tyr_Ser-Thr
SRCP12931humanHK1P19367Y732YDrLVDEysLNAGkQHexokinase_2
SRCP12931humanEGFRP00533Y727sGAFGtVykGLWIPEPK_Tyr_Ser-Thr
SRCP12931humanHNRNPKP61978Y380yAGGrGsyGDLGGPI
SRCP12931humanCTTNQ14247Y486yPAEDStyDEYENDL
SRCP12931humanG6PDP11413Y322EGEATkGyLDDPTVPG6PD_C
SRCP12931humanAGO2Q9UKV8Y749HPTEFDFyLCsHAGIPiwi
SRCP12931humanGSNP06396Y603LKTPsAAyLWVGTGAGelsolin
SRCP12931humanFHL1Q13642-1Y272VFHQEQVyCPDCAkKLIM
SRCP12931humanAFAP1Q8N556Y94SSLPEGyyEEAVPLs
SRCP12931humanPTK2Q05397Y861PIGNQHIyQPVGKPD
SRCP12931humanCTNNB1P35222Y333NIMRTytyEkLLWTT
SRCP12931humanVIL1P09327Y81EQGAAAIyTTQMDDFGelsolin
SRCP12931humanGIT1Q9Y2X7Y246PDHKNGHyIIPQMAD
SRCP12931humanPRC1O43663Y464QTETEMLyGsAPRtPMAP65_ASE1
SRCP12931humanFOSP01100Y30AGDSLSYyHsPADSF
SRCP12931humanTHRAP3Q9Y2W1Y107NrGGYGNyrSNWQNy
SRCP12931humanHCN4Q9Y3Q4Y531RRQYQEKyKQVEQYM
SRCP12931humanPLD2O14939Y511FFWLGKDySNLITKD
SRCP12931humanRRASP10301Y66DPTIEDSyTKICSVDRas
SRCP12931humanSLC11A1P49279Y15QRLSGSSyGSISSPT
SRCP12931humanSDC4P31431Y180KkKDEGsyDLGKKPISyndecan
SRCP12931humanBAIAP2L1Q9UHR4Y293PAPSGRAytsPLIDM
SRCP12931humanTNS3Q68CZ2Y1206sHsFRGAyGLAMKVASH2
SRCP12931humanYAP1P46937-3Y357SGLSMSSySVPRtPD
SRCP12931humanRPS6KA3P51812Y470EIEILLRyGQHPNIIPkinase
SRCP12931humanNDFIP2Q9NV92Y167TTSDTEVyGEFyPVP
SRCP12931humanSTAP2Q9UGK3Y322GDGPAVDyENQDVAS
SRCP12931humanTFGQ92734Y247EGQMYQQyQQQAGYG
SRCP12931humanAKAP8O43823Y152PyRPsySyDyEFDLG
SRCP12931humanSHC1P29353-3Y195EPPDHQyyNDFPGKE
SRCP12931humanPTK2Q05397Y441GDVHQGIyMsPENPAPK_Tyr_Ser-Thr
SRCP12931humanRBM10P98175-2Y905LGArGSsyGVTSTES
SRCP12931humanCAV2P51636Y19LFMDDDsysHHsGLECaveolin
SRCP12931humanGUCY1B1Q02153Y192ESKEEDFyEDLDRFE
SRCP12931humanSDC4P31431Y197kAPtNEFyA______
SRCP12931humanCDC42P60953-1Y64DTAGQEDyDRLRPLSRas
SRCP12931humanSH3GL1Q99961Y315QPSCKALyDFEPENDSH3_1
SRCP12931humanARHGDIBP52566Y24ELdskLNykPPPQksRho_GDI
SRCP12931humanPANX1Q96RD7Y309KTDVLkVyEILPTFD
SRCP12931humanEYA3Q99504Y325HSLLTGSyAQKYGKD
SRCP12931humanNELFCDQ8IXH7-4Y6__MDEDYyGSAAEWGTH1
SRCP12931humanCNN3Q15417Y10HFNkGPsyGLsAEVK
SRCP12931humanCDH5P33151Y685LDARPsLyAQVQKPP
SRCP12931humanEWSR1Q01844Y278HPSSMGVyGQESGGF
SRCP12931humanAKAP8O43823Y150HNPyRPsySyDyEFD
SRCP12931humanEYA3Q99504Y67IPRSSNDyTSQMySA
SRCP12931humanGRIN2AQ12879Y1184GLsNNDQyKLySKHFNMDAR2_C
SRCP12931humanEPS8Q12929Y602LGRADPPytHtIQKQ
SRCP12931humanGSNP06396Y86VPVPTNLyGDFFTGDGelsolin
SRCP12931humanBCAR1P56945Y128SKAQQGLyQVPGPsP
SRCP12931humanCDKN1BP46527Y89GsLPEFyyRPPRPPK
SRCP12931humanEGFRP00533Y944PICtIDVyMIMVKCWPK_Tyr_Ser-Thr
SRCP12931humanG6PDP11413Y112NsyVAGQyDDAASYQG6PD_N
SRCP12931humanTIMP2P16035Y62VDsGNDIyGNPIkRITIMP
SRCP12931humanGRIN2AQ12879Y1423SRGHNDVyISEHVMPNMDAR2_C
SRCP12931humanEGFRP00533Y1125APsRDPHyQDPHstA
SRCP12931humanPBKQ96KB5Y74NPICNDHyRsVyQkRPkinase
SRCP12931humanARHGDIBP52566Y153yGPRPEEyEFLtPVERho_GDI
SRCP12931humanDVL2O14641Y463SDVVDWLyHHVEGFPDEP
SRCP12931humanDNM2P50570Y597NtEQRNVykDLRQIEPH
SRCP12931humanPTPN6P29350Y536QkGQEsEyGNItyPP
SRCP12931humanITGB3P05106Y773DtANNPLyKEAtstFIntegrin_b_cyt
SRCP12931humanPLEKHG2Q9H7P9Y489sEPVKDPyVMFPQNA
SRCP12931humanDMAP1Q9NPF5Y246EQVAEEEyLLQELRKDMAP1
SRCP12931humanTRIM25Q14258Y278NSkFDtIyQILLkkk
SRCP12931humanSYNJ2O15056Y490LLLVGDVyGEEVADK
SRCP12931humanCEACAM1P13688Y520LTATEIIysEVKKQ_
SRCP12931humanSTAT5BP51692Y699tAkAVDGyVkPQIkQ
SRCP12931humanRBM10P98175-2Y16RGDRTGRyGATDRSQ
SRCP12931humanRAC1P63000Y64DTAGQEDyDRLRPLsRas
SRCP12931humanRGS16O15492Y168TLMEKDSyPRFLkSPRGS
SRCP12931humanGRK2P25098Y92FyEEIKKyEkLETEERGS
SRCP12931humanRAF1P04049Y340RGQRDssyyWEIEAS
SRCP12931humanPTENP60484Y315RADNDKEyLVLtLtKPTEN_C2
SRCP12931humanVAMP7P51809Y45SENNKLTySHGNYLFLongin
SRCP12931humanPTK2Q05397Y194ALEKKSNyEVLEkDVFERM_M
SRCP12931humanMEGF10Q96KG7Y1030LSSSENPyATIKDPP
SRCP12931humanCDH5P33151Y658GEMDTTSyDVSVLNs
SRCP12931humanCTNNB1P35222Y654RNEGVAtyAAAVLFR
SRCP12931humanCCDC88CQ9P219Y2025PQTVWyEyGCV____
SRCP12931humanEYA3Q99504Y105TLQQTQPyAVyPQAT
SRCP12931humanNDUFV2P19404Y193VQINDNYyEDLTAKD2Fe-2S_thioredx
SRCP12931humanARHGDIAP52565Y156YGPRAEEyEFLtPVERho_GDI
SRCP12931humanAKAP8O43823Y80PAMHMASyGPEPCTD
SRCP12931humanCCDC88CQ9P219Y2023GDPQTVWyEyGCV__
SRCP12931humanPLSCR1O15162Y74PVyNQPVyNQPVGAA
SRCP12931humanCDH2P19022Y860DSLLVFDyEGSGSTACADH_Y-type_LIR
SRCP12931humanKHSRPQ92945Y317GFGDrNEyGsRIGGG
SRCP12931humanKRASP01116Y64DTAGQEEySAMRDQYRas
SRCP12931humanCHRNA7P36544Y386ASNGNLLyIGFRGLDNeur_chan_memb
SRCP12931humanESR1P03372Y537CKNVVPLyDLLLEML
SRCP12931humanSDC1P18827Y286KkkDEGsysLEEPkQSyndecan
SRCP12931humanVAV3Q9UKW4Y173EDEGGEVyEDLMKAE
SRCP12931humanRHOAP61586Y66DtAGQEDyDRLRPLSRas
SRCP12931humanRETP07949Y905DVyEEDsyVKRsQGRPK_Tyr_Ser-Thr
SRCP12931humanARHGAP35Q9NRY4Y1087DGFDPsDyAEPMDAVRhoGAP_pG1_pG2
SRCP12931humanTHRAP3Q9Y2W1Y118WQNyrQAysPRRGRS
SRCP12931humanGBF1Q92538Y317EQPGsPGySTATEPG
SRCP12931humanCFL1P23528Y68GQtVDDPyAtFVkMLCofilin_ADF
SRCP12931humanAFAP1Q8N556Y451TDPEALHyDyIDVEM
SRCP12931humanFOSP01100Y10FSGFNADyEASSSRC
SRCP12931humanRPS6KA3P51812Y644KFSLSGGyWNSVSDTPkinase
SRCP12931humanGJA1P17302Y313sEQNWANysAEQNRMConnexin43
SRCP12931humanCHRNA7P36544Y442KILEEVRyIANRFRCNeur_chan_memb
SRCP12931humanATP1A1P05023Y149ITGCFSYyQEAKSSkTM
SRCP12931humanPBKQ96KB5Y272DFDDEAYyAALGTRPPkinase
SRCP12931humanATP1A1P05023Y260tARGIVVytGDrtVME1-E2_ATPase
SRCP12931humanTNS3Q68CZ2Y1173QDTSkFWykADISRESH2
SRCP12931humanFLT4P35916Y833EQCEyLSyDASQWEF
SRCP12931humanHNRNPKP61978Y225IkGRAQPyDPNFyDE
SRCP12931humanENGP17813Y614TAALWyIySHTRSPS
SRCP12931humanLPIN1Q14693Y398HLGADGVyLDDLTDM
SRCP12931humanPTTG1IPP53801Y174LFkEENPyARFENN_
SRCP12931humanCAPN2P17655Y625RSGtMNSyEMRkALE
SRCP12931humanEGFRP00533Y915MTFGSkPyDGIPASEPK_Tyr_Ser-Thr
SRCP12931humanDDR2Q16832Y471EQGsNstyDrIFPLR
SRCP12931humanNEDD4P46934-4Y585DGEKGLDyGGVAREW
SRCP12931humanSPRY2O43597Y55AIRNTNEytEGPTVV
SRCP12931humanARHGEF7Q14155-1Y442PAPLTPAyHTLPHPS
SRCP12931humanMPZL1O95297Y241sHQGPVIyAQLDHsG
SRCP12931humanPTK2BQ14289Y402CsIEsDIyAEIPDEt
SRCP12931humanDVL2O14641Y27LDEEETPyLVkIPVPDIX
SRCP12931humanPTPRAP18433-2Y789yIDAFSDyANFK___
SRCP12931humanARP10275Y535MDSYSGPyGDMRLET
SRCP12931humanAGTR1P30556Y319YFLQLLKyIPPKAKS
SRCP12931humanGAKO14976Y1149CTQPRPNyAsNFsVI
SRCP12931humanERBB2P04626Y1248PtAENPEyLGLDVPV
SRCP12931humanTFRCP02786Y20FGGEPLsytRFsLAR
SRCP12931humanBCLAF1Q9NYF8Y284VGNGssRysPsQNsPTHRAP3_BCLAF1
SRCP12931humanPTENP60484Y68HKNHYkIyNLCAERH
SRCP12931humanWASF1Q92558Y125PIPLQETyDVCEQPP
SRCP12931humanLPPQ93052Y300QGRyyEGyyAAGPGy
SRCP12931humanACLYP53396Y227KVDATADyICkVkWG
SRCP12931humanCDC25AP30304Y486SYCEPPSyRPMHHED
SRCP12931humanGBF1Q92538Y1514HTRAASIySSWAEEQ
SRCP12931humanPTK2Q05397Y576RyMEDstyyKAsKGKPK_Tyr_Ser-Thr
SRCP12931humanMYLKQ15746Y471yEDAGsHyLCLLKARI-set
SRCP12931humanEMDP50402Y59sssAAssysFsDLNs
SRCP12931humanHNF4AP41235Y286LQIDDNEyAyLKAIIHormone_recep
SRCP12931humanCDK1P06493Y15EkIGEGtyGVVykGRPkinase
SRCP12931humanARAFP10398Y301LGyRDsGyyWEVPPS
SRCP12931humanCCDC88AQ3V6T2Y1765PRktEDtyFISSAGk
SRCP12931humanSRCP12931Y338VVSEEPIyIVTEyMSPK_Tyr_Ser-Thr
SRCP12931humanLDHAP00338Y10tLkDQLIyNLLkEEQ
SRCP12931humanTNS3Q68CZ2Y1256kGCsNEPyFGsLtALSH2
SRCP12931humanFUBP1Q96AE4Y625yyRQQAAyyAQtsPQDUF1897
SRCP12931humanCNN2Q99439Y12QFNkGPsyGLsAEVk
SRCP12931humanCBLP22681Y731QQIDSCTyEAMyNIQ
SRCP12931humanCNKSR1Q969H4Y26LDDsLQDyPFEDWQLSAM_1
SRCP12931humanFERP16591Y714RQEDGGVyssSGLkQPK_Tyr_Ser-Thr
SRCP12931humanCLTCQ00610Y1477LFITEEDyQALRtSIClathrin
SRCP12931humanARHGAP35Q9NRY4Y1105RNEEENIysVPHDstRhoGAP_pG1_pG2
SRCP12931humanPAK1Q13153S144sNsQKyMsFtDksAE
SRCP12931humanIKBKBO14920Y199ELLEQQKyTVTVDYWPkinase
SRCP12931humanRPS6KA3P51812Y488DVyDDGKyVYVVTELPkinase
SRCP12931humanFUSP35637Y526QDrrErPy_______
SRCP12931humanTP53P04637Y126AkSVTCTySPALNkMP53
SRCP12931humanCORO7P57737Y712SERQLLLyEAEALAG
SRCP12931humanSRCP12931Y419RLIEDNEytARQGAkPK_Tyr_Ser-Thr
SRCP12931humanTHRBP10828Y406FLLAFEHyINYRKHHHormone_recep
SRCP12931humanWNK4Q96J92Y1115PVWMNySySSLCLSS
SRCP12931humanSTAT3P40763Y45IESQDWAyAASkESHSTAT_int
SRCP12931humanNDFIP2Q9NV92Y171TEVyGEFyPVPPPySDUF2370
SRCP12931humanRHBGQ9H310Y429SPPDSQHyEDQVHWQ
SRCP12931humanLASP1Q14847Y171IPtsAPVyQQPQQQP
SRCP12931humanPRKD1Q15139Y463NDTGsRYyKEIPLSEPH
SRCP12931humanDDR2Q16832Y741NLysGDyyRIQGRAVPK_Tyr_Ser-Thr
SRCP12931humanG3BP1Q13283Y133VHNDIFRyQDEVFGGNTF2
SRCP12931humanSHC3Q92529-2Y301PTGEAPTyVNTQQIP
SRCP12931humanEZRP15311Y146kEVHksGyLSsERLIFERM_M
SRCP12931humanRAB34Q9BZG1Y247NsDDsNLyLTASkKK
SRCP12931humanHRASP01112Y32QNHFVDEyDPtIEDsRas
SRCP12931humanCEACAM1P13688Y493NKMNEVtysTLNFEA
SRCP12931humanHNRNPKP61978Y72IkALRTDyNAsVsVPKH_1
SRCP12931humanFUBP1Q96AE4Y58TsLNsNDyGyGGQkR
SRCP12931humanSHC3Q92529-2Y257AGKEQTyyQGRHLGD
SRCP12931humanBMXP51813Y566RYVLDDQyVsSVGTKPK_Tyr_Ser-Thr
SRCP12931humanJUPP14923Y644RNEGTATyAAAVLFR
SRCP12931humanKHSRPQ92945Y688yYRQQAAyYGQtPGPDUF1897
SRCP12931humanCORO7P57737Y738PSTLLPSyDPDTGLV
SRCP12931humanGBF1Q92538Y1488DEGVPASyHTVSLQV
SRCP12931humanPXNP49023Y88PQsssPVyGsSAKTsPaxillin
SRCP12931humanSHC3Q92529-2Y283RQGSSDIySTPEGKL
SRCP12931humanLRP1Q07954Y4507TNFTNPVyATLyMGG
SRCP12931humanXRCC6P12956Y530DEFkELVyPPDyNPEKu_C
SRCP12931humanSHC3Q92529-2Y219DGSDHPyyNSIPSKM
SRCP12931humanVIL1P09327Y46SFFDGDCyIILAIHKGelsolin
SRCP12931humanFIP1L1Q6UN15Y110IKTGAPQyGsyGTAP
SRCP12931humanITGB3P05106Y785stFTNItyRGT____Integrin_b_cyt
SRCP12931humanNPHP1O15259Y721FDLSEQTyDFLGEMR
SRCP12931humanDAPP1Q9UN19Y139kVEEPsIyEsVRVHT
SRCP12931humanOTUB1Q96FW1Y26EGVNCLAyDEAIMAQ
SRCP12931humanEYA3Q99504Y532RFGKkVTyVVIGDGR
SRCP12931humanGAB1Q13480Y627KGDKQVEyLDLDLDs
SRCP12931humanPKD1P98161Y4237NQATEDVyQLEQQLH
SRCP12931humanPRMT5O14744Y324DNLESQTyEVFEkDPPRMT5
SRCP12931humanGAKO14976Y412kGDLDISyITSRIAV
SRCP12931humanKCND3Q9UK17Y108GKLHYPRyECISAYDBTB_2
SRCP12931humanSTAT1P42224Y701DGPkGtGyIktELIs
SRCP12931humanAKAP8O43823Y311KRkQFQLyEEPDTkL
SRCP12931humanNEDD4P46934-4Y111GQVDVPLyPLPTENPC2
SRCP12931humanKIF11P52732Y125ERsPNEEytWEEDPLKinesin
SRCP12931humanGBF1Q92538Y1245RVSHQVAyGLHELLK
SRCP12931humanARHGEF4Q9NR80-3Y94VGSEEDLyDDLHSSS
SRCP12931humanAKAP8O43823Y436TVEFLQEyIVNRNKKAKAP95
SRCP12931humanMMP14P50281Y573GtPRRLLyCQRsLLDDUF3377
SRCP12931humanSRRTQ9BXP5Y175AVKRyNDyKLDFRRQSERRATE_Ars2_N
SRCP12931humanIKBKGQ9Y6K9Y374PLPPAPAyLssPLAL


check button Biological Network Integration of This Kinase and Substrates
(GeneMANIA website)

check button Enriched GO biological processes of the phosphorylation target genes of the kinase
KinaseGOIDGO termP.adjust
SRCIDDescription0.00e+00
SRCGO:1902903regulation of supramolecular fiber organization2.58e-17
SRCGO:0043254regulation of protein-containing complex assembly2.58e-17
SRCGO:0034329cell junction assembly2.58e-17
SRCGO:0032970regulation of actin filament-based process2.69e-17
SRCGO:0031334positive regulation of protein-containing complex assembly2.98e-16
SRCGO:0051347positive regulation of transferase activity3.83e-16
SRCGO:0001667ameboidal-type cell migration5.54e-16
SRCGO:1901653cellular response to peptide5.54e-16
SRCGO:1902905positive regulation of supramolecular fiber organization9.24e-16
SRCGO:0033674positive regulation of kinase activity1.01e-15
SRCGO:0018105peptidyl-serine phosphorylation1.14e-15
SRCGO:0007015actin filament organization1.37e-15
SRCGO:0051495positive regulation of cytoskeleton organization2.31e-15
SRCGO:0018209peptidyl-serine modification3.22e-15
SRCGO:0071375cellular response to peptide hormone stimulus3.64e-15
SRCGO:0007264small GTPase mediated signal transduction7.14e-15
SRCGO:0032271regulation of protein polymerization2.38e-14
SRCGO:0032956regulation of actin cytoskeleton organization3.51e-14
SRCGO:0007173epidermal growth factor receptor signaling pathway4.18e-14
SRCGO:0007265Ras protein signal transduction4.45e-14
SRCGO:0002764immune response-regulating signaling pathway6.00e-14
SRCGO:0002757immune response-activating signaling pathway6.00e-14
SRCGO:0042060wound healing6.98e-14
SRCGO:0006909phagocytosis7.49e-14
SRCGO:0043434response to peptide hormone1.06e-13
SRCGO:0051258protein polymerization1.23e-13
SRCGO:0007163establishment or maintenance of cell polarity2.34e-13
SRCGO:0110053regulation of actin filament organization2.75e-13
SRCGO:0006898receptor-mediated endocytosis5.26e-13
SRCGO:0038127ERBB signaling pathway5.28e-13
SRCGO:0045860positive regulation of protein kinase activity5.73e-13
SRCGO:0007160cell-matrix adhesion6.22e-13
SRCGO:0007044cell-substrate junction assembly6.26e-13
SRCGO:0048041focal adhesion assembly1.37e-12
SRCGO:0062197cellular response to chemical stress1.38e-12
SRCGO:0043410positive regulation of MAPK cascade1.42e-12
SRCGO:0150115cell-substrate junction organization2.07e-12
SRCGO:0045785positive regulation of cell adhesion2.22e-12
SRCGO:0010634positive regulation of epithelial cell migration3.94e-12
SRCGO:0016049cell growth5.25e-12
SRCGO:0046777protein autophosphorylation5.31e-12
SRCGO:0001952regulation of cell-matrix adhesion5.77e-12
SRCGO:1903829positive regulation of protein localization7.69e-12
SRCGO:0032535regulation of cellular component size9.22e-12
SRCGO:0045766positive regulation of angiogenesis9.48e-12
SRCGO:1904018positive regulation of vasculature development9.48e-12
SRCGO:2001233regulation of apoptotic signaling pathway9.60e-12
SRCGO:0018108peptidyl-tyrosine phosphorylation1.26e-11
SRCGO:0045936negative regulation of phosphate metabolic process1.26e-11

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Related Drugs to ZNF587B_SRC


check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

check button Distribution of the number of studies mentioning ZNF587B-SRC and kinase inhibitors the PubMed Abstract (04-01-2024)

Fusion gene - drug pair 1Fusion gene - drug pair 2PMIDPublication dateDOIStudy title

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Related Diseases to ZNF587B_SRC


check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Related diseases from the literature mentioned this fusion gene and drug.
(PubMed, 04-01-2024)
MeSH IDMeSH term

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource


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Clinical Trials of the Found Drugs/Small Molecules


check button Statistics of the Clinical Trials of the Found Kinase Inibitors from clinicaltrials.gov (06-17-2024)

check button Clinical Trials from clinicaltrials.gov (06-17-2024)

Fusion GeneKinase InhibitorNCT IDStudy StatusPhasesDisease# EnrolmentDate