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Fusion Protein:KDM4B-CHAF1A |
Fusion Gene and Fusion Protein Summary |
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Fusion partner gene information | Fusion gene name: KDM4B-CHAF1A | FusionPDB ID: 41799 | FusionGDB2.0 ID: 41799 | Hgene | Tgene | Gene symbol | KDM4B | CHAF1A | Gene ID | 23030 | 10036 |
Gene name | lysine demethylase 4B | chromatin assembly factor 1 subunit A | |
Synonyms | JMJD2B|TDRD14B | CAF-1|CAF1|CAF1B|CAF1P150|P150 | |
Cytomap | 19p13.3 | 19p13.3 | |
Type of gene | protein-coding | protein-coding | |
Description | lysine-specific demethylase 4BjmjC domain-containing histone demethylation protein 3Bjumonji domain containing 2Bjumonji domain-containing protein 2Blysine (K)-specific demethylase 4Btudor domain containing 14B | chromatin assembly factor 1 subunit ACAF-1 subunit ACAF-I 150 kDa subunitCAF-I p150CTB-50L17.7chromatin assembly factor I (150 kDa)chromatin assembly factor I p150 subunithp150 | |
Modification date | 20200313 | 20200313 | |
UniProtAcc | O94953 Main function of 5'-partner protein: FUNCTION: Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate. {ECO:0000269|PubMed:16603238, ECO:0000269|PubMed:28262558}. | Q13111 Main function of 5'-partner protein: FUNCTION: Core component of the CAF-1 complex, a complex that is thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. It may play a role in heterochromatin maintenance in proliferating cells by bringing newly synthesized cbx proteins to heterochromatic DNA replication foci. {ECO:0000250|UniProtKB:Q5R1T0}. | |
Ensembl transtripts involved in fusion gene | ENST ids | ENST00000159111, ENST00000381759, ENST00000536461, ENST00000592175, | ENST00000587368, ENST00000301280, |
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0) | * DoF score | 30 X 16 X 14=6720 | 5 X 6 X 6=180 |
# samples | 38 | 7 | |
** MAII score | log2(38/6720*10)=-4.14438990933518 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(7/180*10)=-1.36257007938471 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
Fusion gene context | PubMed: KDM4B [Title/Abstract] AND CHAF1A [Title/Abstract] AND fusion [Title/Abstract] | ||
Fusion neoantigen context | PubMed: KDM4B [Title/Abstract] AND CHAF1A [Title/Abstract] AND neoantigen [Title/Abstract] | ||
Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0) | KDM4B(5082515)-CHAF1A(4418017), # samples:2 | ||
Anticipated loss of major functional domain due to fusion event. | KDM4B-CHAF1A seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. KDM4B-CHAF1A seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. KDM4B-CHAF1A seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. KDM4B-CHAF1A seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
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Partner | Gene | GO ID | GO term | PubMed ID |
Hgene | KDM4B | GO:0033169 | histone H3-K9 demethylation | 21914792 |
Hgene | KDM4B | GO:0070544 | histone H3-K36 demethylation | 21914792 |
Tgene | CHAF1A | GO:0006335 | DNA replication-dependent nucleosome assembly | 14718166 |
Tgene | CHAF1A | GO:0031497 | chromatin assembly | 8858152 |
![]() Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:5082515/chr19:4418017) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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![]() * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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![]() * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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Fusion Amino Acid Sequences |
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Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
ENST00000159111 | KDM4B | chr19 | 5082515 | + | ENST00000301280 | CHAF1A | chr19 | 4418017 | + | 3414 | 1136 | 218 | 3046 | 942 |
ENST00000381759 | KDM4B | chr19 | 5082515 | + | ENST00000301280 | CHAF1A | chr19 | 4418017 | + | 3403 | 1125 | 207 | 3035 | 942 |
ENST00000536461 | KDM4B | chr19 | 5082515 | + | ENST00000301280 | CHAF1A | chr19 | 4418017 | + | 3236 | 958 | 40 | 2868 | 942 |
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Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
ENST00000159111 | ENST00000301280 | KDM4B | chr19 | 5082515 | + | CHAF1A | chr19 | 4418017 | + | 0.001380299 | 0.9986197 |
ENST00000381759 | ENST00000301280 | KDM4B | chr19 | 5082515 | + | CHAF1A | chr19 | 4418017 | + | 0.001337451 | 0.9986626 |
ENST00000536461 | ENST00000301280 | KDM4B | chr19 | 5082515 | + | CHAF1A | chr19 | 4418017 | + | 0.00129263 | 0.9987074 |
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Get the fusion protein sequences from here. |
Fusion protein sequence information is available in the fasta format. >FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP |
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Fusion Protein Breakpoint Sequences for KDM4B-CHAF1A |
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Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | Length(fusion protein) | BP in fusion protein | Peptide |
KDM4B | chr19 | 5082515 | CHAF1A | chr19 | 4418017 | 1125 | 305 | ATLRWIDYGKVATQITKKFVKGSTEK |
KDM4B | chr19 | 5082515 | CHAF1A | chr19 | 4418017 | 1136 | 305 | ATLRWIDYGKVATQITKKFVKGSTEK |
KDM4B | chr19 | 5082515 | CHAF1A | chr19 | 4418017 | 958 | 305 | ATLRWIDYGKVATQITKKFVKGSTEK |
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Potential FusionNeoAntigen Information of KDM4B-CHAF1A in HLA I |
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KDM4B-CHAF1A_5082515_4418017.msa |
![]() * We used NetMHCpan v4.1 (%rank<0.5) and deepHLApan v1.1 (immunogenic score>0.5) |
Fusion gene | Hchr | Hbp | Tgene | Tchr | Tbp | HLA I | FusionNeoAntigen peptide | Binding score | Immunogenic score | Neoantigen start (at BP 13) | Neoantigen end (at BP 13) |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-A30:08 | KVATQITKK | 0.9977 | 0.5571 | 9 | 18 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-B57:01 | VATQITKKF | 0.9972 | 0.9211 | 10 | 19 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-A24:25 | DYGKVATQI | 0.9951 | 0.5026 | 6 | 15 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-A24:20 | DYGKVATQI | 0.9947 | 0.5014 | 6 | 15 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-B58:02 | VATQITKKF | 0.9935 | 0.8795 | 10 | 19 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-B15:17 | VATQITKKF | 0.9927 | 0.8136 | 10 | 19 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-B15:16 | VATQITKKF | 0.9885 | 0.7254 | 10 | 19 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-B57:03 | VATQITKKF | 0.9874 | 0.9254 | 10 | 19 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-B58:01 | VATQITKKF | 0.982 | 0.8328 | 10 | 19 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-B57:01 | KVATQITKKF | 0.9995 | 0.9268 | 9 | 19 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-B57:03 | KVATQITKKF | 0.9928 | 0.9477 | 9 | 19 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-A32:13 | KVATQITKKF | 0.9746 | 0.9229 | 9 | 19 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-A24:02 | DYGKVATQI | 0.9947 | 0.5014 | 6 | 15 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-C03:08 | VATQITKKF | 0.9945 | 0.8349 | 10 | 19 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-C03:19 | VATQITKKF | 0.9933 | 0.9722 | 10 | 19 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-C15:04 | VATQITKKF | 0.9787 | 0.8543 | 10 | 19 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-C03:07 | VATQITKKF | 0.9718 | 0.9685 | 10 | 19 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-C15:06 | VATQITKKF | 0.9101 | 0.8878 | 10 | 19 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-C07:95 | VATQITKKF | 0.7694 | 0.5697 | 10 | 19 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-C03:14 | VATQITKKF | 0.6853 | 0.9507 | 10 | 19 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-C12:12 | VATQITKKF | 0.6147 | 0.9217 | 10 | 19 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-C12:04 | VATQITKKF | 0.5076 | 0.9862 | 10 | 19 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-C06:03 | VATQITKKF | 0.5066 | 0.9883 | 10 | 19 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-C02:06 | VATQITKKF | 0.2708 | 0.951 | 10 | 19 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-C03:02 | VATQITKKF | 0.9981 | 0.9513 | 10 | 19 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-A30:01 | KVATQITKK | 0.9976 | 0.7097 | 9 | 18 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-B57:10 | VATQITKKF | 0.9972 | 0.9211 | 10 | 19 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-C03:03 | VATQITKKF | 0.9967 | 0.9736 | 10 | 19 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-C03:04 | VATQITKKF | 0.9967 | 0.9736 | 10 | 19 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-C03:67 | VATQITKKF | 0.9955 | 0.9631 | 10 | 19 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-B58:06 | VATQITKKF | 0.9949 | 0.8267 | 10 | 19 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-B57:04 | VATQITKKF | 0.9911 | 0.6159 | 10 | 19 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-A30:01 | TQITKKFVK | 0.9845 | 0.6246 | 12 | 21 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-C03:17 | VATQITKKF | 0.9804 | 0.9564 | 10 | 19 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-C15:09 | VATQITKKF | 0.9787 | 0.8543 | 10 | 19 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-B15:13 | VATQITKKF | 0.9735 | 0.6433 | 10 | 19 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-C03:05 | VATQITKKF | 0.9715 | 0.8547 | 10 | 19 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-B57:02 | VATQITKKF | 0.9675 | 0.8899 | 10 | 19 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-B15:24 | VATQITKKF | 0.835 | 0.7757 | 10 | 19 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-B35:43 | VATQITKKF | 0.8319 | 0.7733 | 10 | 19 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-C16:04 | VATQITKKF | 0.8271 | 0.9655 | 10 | 19 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-C12:02 | VATQITKKF | 0.8209 | 0.9484 | 10 | 19 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-C12:03 | VATQITKKF | 0.6735 | 0.9689 | 10 | 19 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-C16:01 | VATQITKKF | 0.6254 | 0.967 | 10 | 19 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-C16:02 | VATQITKKF | 0.5814 | 0.9842 | 10 | 19 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-C06:02 | VATQITKKF | 0.5566 | 0.9859 | 10 | 19 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-C06:17 | VATQITKKF | 0.5566 | 0.9859 | 10 | 19 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-C06:08 | VATQITKKF | 0.3884 | 0.99 | 10 | 19 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-C02:10 | VATQITKKF | 0.3878 | 0.9731 | 10 | 19 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-C02:02 | VATQITKKF | 0.3878 | 0.9731 | 10 | 19 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-B57:10 | KVATQITKKF | 0.9995 | 0.9268 | 9 | 19 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-B58:06 | KVATQITKKF | 0.9987 | 0.7053 | 9 | 19 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-B15:24 | KVATQITKKF | 0.9981 | 0.7526 | 9 | 19 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-A32:01 | KVATQITKKF | 0.9959 | 0.8612 | 9 | 19 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | HLA-A30:01 | ATQITKKFVK | 0.9883 | 0.6872 | 11 | 21 |
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Potential FusionNeoAntigen Information of KDM4B-CHAF1A in HLA II |
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KDM4B-CHAF1A_5082515_4418017.msa |
![]() * We used NetMHCIIpan v4.1 (%rank<0.5). |
Fusion gene | Hchr | Hbp | Tgene | Tchr | Tbp | HLA II | FusionNeoAntigen peptide | Neoantigen start (at BP 13) | Neoantigen end (at BP 13) |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | DRB1-1220 | YGKVATQITKKFVKG | 7 | 22 |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 | DRB1-1221 | YGKVATQITKKFVKG | 7 | 22 |
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Fusion breakpoint peptide structures of KDM4B-CHAF1A |
![]() * The minimum length of the amino acid sequence in RoseTTAFold is 14AA. Here, we predicted the 14AA fusion protein breakpoint sequence not the fusion neoantigen peptide, which is shorter than 14 AA. |
File name | BPseq | Hgene | Tgene | Hchr | Hbp | Tchr | Tbp | AAlen |
1491 | DYGKVATQITKKFV | KDM4B | CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 1136 |
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Filtering FusionNeoAntigens Through Checking the Interaction with HLAs in 3D of KDM4B-CHAF1A |
![]() * We used Glide to predict the interaction between HLAs and neoantigens. |
HLA allele | PDB ID | File name | BPseq | Docking score | Glide score |
HLA-B14:02 | 3BVN | 1491 | DYGKVATQITKKFV | -7.15543 | -7.26883 |
HLA-B14:02 | 3BVN | 1491 | DYGKVATQITKKFV | -4.77435 | -5.80965 |
HLA-B52:01 | 3W39 | 1491 | DYGKVATQITKKFV | -6.80875 | -6.92215 |
HLA-B52:01 | 3W39 | 1491 | DYGKVATQITKKFV | -4.20386 | -5.23916 |
HLA-A11:01 | 4UQ2 | 1491 | DYGKVATQITKKFV | -7.5194 | -8.5547 |
HLA-A11:01 | 4UQ2 | 1491 | DYGKVATQITKKFV | -6.9601 | -7.0735 |
HLA-A24:02 | 5HGA | 1491 | DYGKVATQITKKFV | -7.52403 | -7.63743 |
HLA-A24:02 | 5HGA | 1491 | DYGKVATQITKKFV | -5.82433 | -6.85963 |
HLA-B27:05 | 6PYJ | 1491 | DYGKVATQITKKFV | -3.28285 | -4.31815 |
HLA-B44:05 | 3DX8 | 1491 | DYGKVATQITKKFV | -5.91172 | -6.94702 |
HLA-B44:05 | 3DX8 | 1491 | DYGKVATQITKKFV | -4.24346 | -4.35686 |
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Vaccine Design for the FusionNeoAntigens of KDM4B-CHAF1A |
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Fusion gene | Hchr | Hbp | Tchr | Tbp | Start in +/-13AA | End in +/-13AA | FusionNeoAntigen peptide sequence | FusionNeoAntigen RNA sequence |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 10 | 19 | VATQITKKF | GCCACTCAGATAACTAAGAAATTCGTC |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 11 | 21 | ATQITKKFVK | ACTCAGATAACTAAGAAATTCGTCAAAGGC |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 12 | 21 | TQITKKFVK | CAGATAACTAAGAAATTCGTCAAAGGC |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 6 | 15 | DYGKVATQI | TACGGCAAAGTGGCCACTCAGATAACT |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 9 | 18 | KVATQITKK | GTGGCCACTCAGATAACTAAGAAATTC |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 9 | 19 | KVATQITKKF | GTGGCCACTCAGATAACTAAGAAATTCGTC |
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Fusion gene | Hchr | Hbp | Tchr | Tbp | Start in +/-13AA | End in +/-13AA | FusionNeoAntigen peptide | FusionNEoAntigen RNA sequence |
KDM4B-CHAF1A | chr19 | 5082515 | chr19 | 4418017 | 7 | 22 | YGKVATQITKKFVKG | GGCAAAGTGGCCACTCAGATAACTAAGAAATTCGTCAAAGGCTCT |
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Information of the samples that have these potential fusion neoantigens of KDM4B-CHAF1A |
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Cancer type | Fusion gene | Hchr | Hbp | Henst | Tchr | Tbp | Tenst | Sample |
LGG | KDM4B-CHAF1A | chr19 | 5082515 | ENST00000159111 | chr19 | 4418017 | ENST00000301280 | TCGA-DU-8163-01A |
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Potential target of CAR-T therapy development for KDM4B-CHAF1A |
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![]() * Minus value of BPloci means that the break point is located before the CDS. |
- In-frame and retained 'Transmembrane'. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
![]() * We used DeepLoc 1.0. The order of the X-axis of the barplot is as follows: Entry_ID, Localization, Type, Nucleus, Cytoplasm, Extracellular, Mitochondrion, Cell_membrane, Endoplasmic_reticulum, Plastid, Golgi.apparatus, Lysosome.Vacuole, Peroxisome. Y-axis is the output score of DeepLoc. Clicking the image will open a new tab with a large image. |
Hgene | Hchr | Hbp | Henst | Tgene | Tchr | Tbp | Tenst | DeepLoc result |
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Related Drugs to KDM4B-CHAF1A |
![]() (Manual curation of PubMed, 04-30-2022 + MyCancerGenome) |
Hgene | Tgene | Drug | Source | PMID |
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Related Diseases to KDM4B-CHAF1A |
![]() (Manual curation of PubMed, 04-30-2022 + MyCancerGenome) |
Hgene | Tgene | Disease | Source | PMID |
![]() (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |