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Center for Computational Systems Medicine
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Fusion Gene and Fusion Protein Summary

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Fusion Amino Acid Sequences (multiple BPs and multiple gene isoforms)

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Fusion Protein Breakpoint Sequences - (for the Screening of the FusionNeoAntigens)

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Potential FusionNeoAntigens in HLA I - (netMHCpan v4.1 + deepHLApan v1.1)

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Potential FusionNeoAntigens in HLA II - (netMHCIIpan v4.1)

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Fusion Breakpoint 14 AA Peptide Structure - (RoseTTAFold)

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Filtering FusionNeoAntigens Through Checking the Interaction with HLAs in 3D - (Glide)

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Vaccine Design for the FusionNeoAntigens (RNA/protein sequences)

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Potential target of CAR-T therapy development

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Information on the samples that have these potential fusion neoantigens

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Fusion Protein Targeting Drugs - (Manual Curation)

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Fusion Protein Related diseases - (Manual Curation)

Fusion Protein:LDLR-ZGLP1

Fusion Gene and Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: LDLR-ZGLP1
FusionPDB ID: 44420
FusionGDB2.0 ID: 44420
HgeneTgene
Gene symbol

LDLR

ZGLP1

Gene ID

3949

100125288

Gene namelow density lipoprotein receptorzinc finger GATA like protein 1
SynonymsFH|FHC|FHCL1|LDLCQ2GATAD3|GLP-1|GLP1
Cytomap

19p13.2

19p13.2

Type of geneprotein-codingprotein-coding
Descriptionlow-density lipoprotein receptorLDL receptorlow-density lipoprotein receptor class A domain-containing protein 3GATA-type zinc finger protein 1GATA zinc finger domain containing 3GATA-like protein 1
Modification date2020032220200313
UniProtAcc

Q5SW96

Main function of 5'-partner protein: FUNCTION: Adapter protein (clathrin-associated sorting protein (CLASP)) required for efficient endocytosis of the LDL receptor (LDLR) in polarized cells such as hepatocytes and lymphocytes, but not in non-polarized cells (fibroblasts). May be required for LDL binding and internalization but not for receptor clustering in coated pits. May facilitate the endocytocis of LDLR and LDLR-LDL complexes from coated pits by stabilizing the interaction between the receptor and the structural components of the pits. May also be involved in the internalization of other LDLR family members. Binds to phosphoinositides, which regulate clathrin bud assembly at the cell surface. Required for trafficking of LRP2 to the endocytic recycling compartment which is necessary for LRP2 proteolysis, releasing a tail fragment which translocates to the nucleus and mediates transcriptional repression (By similarity). {ECO:0000250|UniProtKB:D3ZAR1, ECO:0000269|PubMed:15728179}.
.
Ensembl transtripts involved in fusion geneENST idsENST00000455727, ENST00000535915, 
ENST00000545707, ENST00000557933, 
ENST00000558013, ENST00000558518, 
ENST00000560628, 
ENST00000403352, 
ENST00000403903, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score23 X 17 X 15=58654 X 9 X 4=144
# samples 335
** MAII scorelog2(33/5865*10)=-4.15159317867005
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(5/144*10)=-1.52606881166759
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Fusion gene context

PubMed: LDLR [Title/Abstract] AND ZGLP1 [Title/Abstract] AND fusion [Title/Abstract]

Fusion neoantigen context

PubMed: LDLR [Title/Abstract] AND ZGLP1 [Title/Abstract] AND neoantigen [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)LDLR(11200291)-ZGLP1(10419067), # samples:2
Anticipated loss of major functional domain due to fusion event.LDLR-ZGLP1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
LDLR-ZGLP1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
LDLR-ZGLP1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
LDLR-ZGLP1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
LDLR-ZGLP1 seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
LDLR-ZGLP1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
LDLR-ZGLP1 seems lost the major protein functional domain in Tgene partner, which is a transcription factor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:11200291/chr19:10419067)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonRetention analysis results of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features, are available here.

check buttonFusion gene breakpoints across LDLR (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ZGLP1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


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Fusion Amino Acid Sequences


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)
ENST00000558518LDLRchr1911224438+ENST00000403352ZGLP1chr1910415884-190717731691890573
ENST00000557933LDLRchr1911224438+ENST00000403352ZGLP1chr1910415884-18071673691790573
ENST00000455727LDLRchr1911224438+ENST00000403352ZGLP1chr1910415884-13021168681285405
ENST00000535915LDLRchr1911224438+ENST00000403352ZGLP1chr1910415884-16831549681666532
ENST00000545707LDLRchr1911224438+ENST00000403352ZGLP1chr1910415884-14251291681408446
ENST00000558013LDLRchr1911224438+ENST00000403352ZGLP1chr1910415884-17911657531774573
ENST00000558518LDLRchr1911224437+ENST00000403352ZGLP1chr1910415883-190717731691890573
ENST00000557933LDLRchr1911224437+ENST00000403352ZGLP1chr1910415883-18071673691790573
ENST00000455727LDLRchr1911224437+ENST00000403352ZGLP1chr1910415883-13021168681285405
ENST00000535915LDLRchr1911224437+ENST00000403352ZGLP1chr1910415883-16831549681666532
ENST00000545707LDLRchr1911224437+ENST00000403352ZGLP1chr1910415883-14251291681408446
ENST00000558013LDLRchr1911224437+ENST00000403352ZGLP1chr1910415883-17911657531774573

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000558518ENST00000403352LDLRchr1911224438+ZGLP1chr1910415884-0.0161031070.98389685
ENST00000557933ENST00000403352LDLRchr1911224438+ZGLP1chr1910415884-0.0164695660.98353046
ENST00000455727ENST00000403352LDLRchr1911224438+ZGLP1chr1910415884-0.0173866750.98261327
ENST00000535915ENST00000403352LDLRchr1911224438+ZGLP1chr1910415884-0.0159405970.98405933
ENST00000545707ENST00000403352LDLRchr1911224438+ZGLP1chr1910415884-0.0206875040.97931254
ENST00000558013ENST00000403352LDLRchr1911224438+ZGLP1chr1910415884-0.0168461690.9831539
ENST00000558518ENST00000403352LDLRchr1911224437+ZGLP1chr1910415883-0.0161031070.98389685
ENST00000557933ENST00000403352LDLRchr1911224437+ZGLP1chr1910415883-0.0164695660.98353046
ENST00000455727ENST00000403352LDLRchr1911224437+ZGLP1chr1910415883-0.0173866750.98261327
ENST00000535915ENST00000403352LDLRchr1911224437+ZGLP1chr1910415883-0.0159405970.98405933
ENST00000545707ENST00000403352LDLRchr1911224437+ZGLP1chr1910415883-0.0206875040.97931254
ENST00000558013ENST00000403352LDLRchr1911224437+ZGLP1chr1910415883-0.0168461690.9831539

check button Predicted full-length fusion amino acid sequences. For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among all the predicted ones.

Get the fusion protein sequences from here.

Fusion protein sequence information is available in the fasta format.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

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Fusion Protein Breakpoint Sequences for LDLR-ZGLP1

check button +/-13 AA sequence from the breakpoints of the fusion protein sequences.
HgeneHchrHbpTgeneTchrTbpLength(fusion protein)BP in fusion proteinPeptide
LDLRchr1911224437ZGLP1chr19104158831168367SKPRAIVVDPVHGYKKYGTRCSSCWL
LDLRchr1911224437ZGLP1chr19104158831291408SKPRAIVVDPVHGYKKYGTRCSSCWL
LDLRchr1911224437ZGLP1chr19104158831549494SKPRAIVVDPVHGYKKYGTRCSSCWL
LDLRchr1911224437ZGLP1chr19104158831657535SKPRAIVVDPVHGYKKYGTRCSSCWL
LDLRchr1911224437ZGLP1chr19104158831673535SKPRAIVVDPVHGYKKYGTRCSSCWL
LDLRchr1911224437ZGLP1chr19104158831773535SKPRAIVVDPVHGYKKYGTRCSSCWL
LDLRchr1911224438ZGLP1chr19104158841168367SKPRAIVVDPVHGYKKYGTRCSSCWL
LDLRchr1911224438ZGLP1chr19104158841291408SKPRAIVVDPVHGYKKYGTRCSSCWL
LDLRchr1911224438ZGLP1chr19104158841549494SKPRAIVVDPVHGYKKYGTRCSSCWL
LDLRchr1911224438ZGLP1chr19104158841657535SKPRAIVVDPVHGYKKYGTRCSSCWL
LDLRchr1911224438ZGLP1chr19104158841673535SKPRAIVVDPVHGYKKYGTRCSSCWL
LDLRchr1911224438ZGLP1chr19104158841773535SKPRAIVVDPVHGYKKYGTRCSSCWL

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Potential FusionNeoAntigen Information of LDLR-ZGLP1 in HLA I

check button Multiple sequence alignments of the potential FusionNeoAntigens per fusion breakpoints. If the MSA is empty, then it means that there were predicted fusion neoantigens in this fusion breakpoint, but those predicted fusion neoantigens were not across the breakpoint, which is not fusion-specific.
LDLR-ZGLP1_11224437_10415883.msa

check button Potential FusionNeoAntigen Information
* We used NetMHCpan v4.1 (%rank<0.5) and deepHLApan v1.1 (immunogenic score>0.5)
Fusion geneHchrHbpTgeneTchrTbpHLA IFusionNeoAntigen peptideBinding scoreImmunogenic scoreNeoantigen start (at BP 13)Neoantigen end (at BP 13)
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:25IVVDPVHGY0.99720.8925514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:01IVVDPVHGY0.99530.8613514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B35:08IVVDPVHGY0.99110.788514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:02IVVDPVHGY0.98890.8956514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:17IVVDPVHGY0.98450.8621514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B35:01IVVDPVHGY0.98430.8379514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B35:01DPVHGYKKY0.94790.7462817
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B35:08DPVHGYKKY0.94340.7118817
LDLR-ZGLP1chr1911224437chr19104158831168HLA-A30:08VVDPVHGYK0.93590.7606615
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:16IVVDPVHGY0.92630.7293514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B35:05IVVDPVHGY0.86540.5287514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-A74:03VVDPVHGYK0.8320.5498615
LDLR-ZGLP1chr1911224437chr19104158831168HLA-A74:11VVDPVHGYK0.8320.5498615
LDLR-ZGLP1chr1911224437chr19104158831168HLA-A74:09VVDPVHGYK0.8320.5498615
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:03IVVDPVHGY0.80530.6946514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-A32:13IVVDPVHGY0.18680.9393514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:01AIVVDPVHGY0.99890.8668414
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:25AIVVDPVHGY0.99070.9377414
LDLR-ZGLP1chr1911224437chr19104158831168HLA-A80:01AIVVDPVHGY0.71080.5302414
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:25RAIVVDPVHGY0.99980.8949314
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:01RAIVVDPVHGY0.99980.7959314
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:17RAIVVDPVHGY0.99860.8909314
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:16RAIVVDPVHGY0.99750.8234314
LDLR-ZGLP1chr1911224437chr19104158831168HLA-A03:12IVVDPVHGYKK0.9970.5904516
LDLR-ZGLP1chr1911224437chr19104158831168HLA-A03:25IVVDPVHGYKK0.99690.5538516
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:05IVVDPVHGY0.99310.8164514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:21IVVDPVHGY0.98770.8382514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:07IVVDPVHGY0.98420.6108514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:31IVVDPVHGY0.98320.8317514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-C12:16IVVDPVHGY0.84220.9464514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:04IVVDPVHGY0.73090.8857514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-C07:19IVVDPVHGY0.68950.6252514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-C15:04IVVDPVHGY0.6880.9087514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-C07:10IVVDPVHGY0.68540.9429514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-C07:27IVVDPVHGY0.58170.9133514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-C07:95IVVDPVHGY0.52710.5173514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-C03:14IVVDPVHGY0.4250.9779514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-C12:12IVVDPVHGY0.36280.8462514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-C06:03IVVDPVHGY0.35860.9879514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-C12:04IVVDPVHGY0.35750.9887514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:07AIVVDPVHGY0.99640.6497414
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:05AIVVDPVHGY0.95570.8504414
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:07RAIVVDPVHGY0.99940.5795314
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:05RAIVVDPVHGY0.99760.77314
LDLR-ZGLP1chr1911224437chr19104158831168HLA-C15:04RAIVVDPVHGY0.99760.9024314
LDLR-ZGLP1chr1911224437chr19104158831168HLA-A03:01IVVDPVHGYKK0.99690.5538516
LDLR-ZGLP1chr1911224437chr19104158831168HLA-C03:14RAIVVDPVHGY0.97350.9656314
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:39IVVDPVHGY0.99660.7635514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:125IVVDPVHGY0.99530.8613514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:33IVVDPVHGY0.99530.8613514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:34IVVDPVHGY0.99530.8613514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:27IVVDPVHGY0.99510.8627514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:20IVVDPVHGY0.99430.8926514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:11IVVDPVHGY0.99330.8157514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:08IVVDPVHGY0.99290.7922514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:135IVVDPVHGY0.99280.8492514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:50IVVDPVHGY0.99080.8836514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B35:28IVVDPVHGY0.98980.8952514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B35:43IVVDPVHGY0.98920.7925514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B35:11IVVDPVHGY0.98740.8177514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:35IVVDPVHGY0.98640.8532514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B35:77IVVDPVHGY0.98430.8379514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B35:23IVVDPVHGY0.98230.831514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B35:20IVVDPVHGY0.97810.9024514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:24IVVDPVHGY0.96780.8614514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B35:24DPVHGYKKY0.96570.7791817
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B35:30IVVDPVHGY0.95530.7088514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B35:17IVVDPVHGY0.95530.7088514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:12IVVDPVHGY0.9520.8319514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-C03:02IVVDPVHGY0.95070.9581514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:13IVVDPVHGY0.94850.5515514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B35:77DPVHGYKKY0.94790.7462817
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:53IVVDPVHGY0.9440.8375514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B35:23DPVHGYKKY0.93920.6965817
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B35:24IVVDPVHGY0.91180.8896514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-A25:01IVVDPVHGY0.88010.8602514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-C07:22IVVDPVHGY0.83510.5935514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B35:17DPVHGYKKY0.83480.5538817
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B35:30DPVHGYKKY0.83480.5538817
LDLR-ZGLP1chr1911224437chr19104158831168HLA-A74:01VVDPVHGYK0.8320.5498615
LDLR-ZGLP1chr1911224437chr19104158831168HLA-C12:02IVVDPVHGY0.79330.9557514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B35:11DPVHGYKKY0.7740.7821817
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:54IVVDPVHGY0.76240.828514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B18:04DPVHGYKKY0.75050.8115817
LDLR-ZGLP1chr1911224437chr19104158831168HLA-C07:17IVVDPVHGY0.69360.9472514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-C15:09IVVDPVHGY0.6880.9087514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-C12:03IVVDPVHGY0.61030.962514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-C16:04IVVDPVHGY0.50720.9603514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B18:04IVVDPVHGY0.47150.8972514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B18:07DPVHGYKKY0.44060.724817
LDLR-ZGLP1chr1911224437chr19104158831168HLA-A32:01IVVDPVHGY0.32940.9114514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-C16:01IVVDPVHGY0.29860.9663514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-C16:02IVVDPVHGY0.2230.9878514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B18:07IVVDPVHGY0.19210.8254514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-C02:02IVVDPVHGY0.07190.9657514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-C02:10IVVDPVHGY0.07190.9657514
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:08DPVHGYKKY0.06240.6613817
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:11DPVHGYKKY0.05620.663817
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B35:43DPVHGYKKY0.03970.6691817
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:33AIVVDPVHGY0.99890.8668414
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:27AIVVDPVHGY0.99890.9021414
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:34AIVVDPVHGY0.99890.8668414
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:125AIVVDPVHGY0.99890.8668414
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:135AIVVDPVHGY0.99850.8672414
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:50AIVVDPVHGY0.99790.9062414
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:35AIVVDPVHGY0.99580.8663414
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:39AIVVDPVHGY0.99050.8405414
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:12AIVVDPVHGY0.9890.8998414
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:20AIVVDPVHGY0.95790.9287414
LDLR-ZGLP1chr1911224437chr19104158831168HLA-A25:01AIVVDPVHGY0.65490.9296414
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:34RAIVVDPVHGY0.99980.7959314
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:27RAIVVDPVHGY0.99980.8601314
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:125RAIVVDPVHGY0.99980.7959314
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:39RAIVVDPVHGY0.99980.7552314
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:135RAIVVDPVHGY0.99980.7994314
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:33RAIVVDPVHGY0.99980.7959314
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:12RAIVVDPVHGY0.99970.7917314
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:50RAIVVDPVHGY0.99970.8686314
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B58:06RAIVVDPVHGY0.99950.6925314
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B57:04RAIVVDPVHGY0.99930.7482314
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:35RAIVVDPVHGY0.99890.7985314
LDLR-ZGLP1chr1911224437chr19104158831168HLA-C02:02RAIVVDPVHGY0.99790.9663314
LDLR-ZGLP1chr1911224437chr19104158831168HLA-C02:10RAIVVDPVHGY0.99790.9663314
LDLR-ZGLP1chr1911224437chr19104158831168HLA-C15:09RAIVVDPVHGY0.99760.9024314
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B15:20RAIVVDPVHGY0.99750.8863314
LDLR-ZGLP1chr1911224437chr19104158831168HLA-B35:28RAIVVDPVHGY0.99640.901314
LDLR-ZGLP1chr1911224437chr19104158831168HLA-C03:02RAIVVDPVHGY0.990.9334314
LDLR-ZGLP1chr1911224437chr19104158831168HLA-C12:02RAIVVDPVHGY0.98570.9511314

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Potential FusionNeoAntigen Information of LDLR-ZGLP1 in HLA II

check button Multiple sequence alignments of the potential FusionNeoAntigens per fusion breakpoints. If the MSA is empty, then it means that there were predicted fusion neoantigens in this fusion breakpoint, but those predicted fusion neoantigens were not across the breakpoint, which is not fusion-specific.
LDLR-ZGLP1_11224437_10415883.msa

check button Potential FusionNeoAntigen Information
* We used NetMHCIIpan v4.1 (%rank<0.5).
Fusion geneHchrHbpTgeneTchrTbpHLA IIFusionNeoAntigen peptideNeoantigen start (at BP 13)Neoantigen end (at BP 13)
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0301KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0301PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0301SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0301RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0301AIVVDPVHGYKKYGT419
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0303PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0303KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0303SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0303RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0303AIVVDPVHGYKKYGT419
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0305PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0305KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0305SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0305RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0307PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0307KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0307SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0307RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0310KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0310PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0310SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0310RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0310AIVVDPVHGYKKYGT419
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0313KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0313PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0313SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0313RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0313AIVVDPVHGYKKYGT419
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0315KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0315PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0315SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0315RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0318KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0318PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0318SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0318RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0318AIVVDPVHGYKKYGT419
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0320PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0320KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0320SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0320RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0320AIVVDPVHGYKKYGT419
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0322KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0322PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0322SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0322RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0322AIVVDPVHGYKKYGT419
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0324KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0324PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0324SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0324RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0326PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0326KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0326SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0326RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0326AIVVDPVHGYKKYGT419
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0328KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0328PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0328SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0328RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0328AIVVDPVHGYKKYGT419
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0330KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0330PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0330SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0330RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0330AIVVDPVHGYKKYGT419
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0332KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0332PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0332SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0332RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0332AIVVDPVHGYKKYGT419
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0334KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0334PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0334SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0334RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0334AIVVDPVHGYKKYGT419
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0336KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0336PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0336SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0336RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0336AIVVDPVHGYKKYGT419
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0338PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0338KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0338SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0338RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0340PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0340KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0340SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0340RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0342PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0342KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0342SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0342RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0342AIVVDPVHGYKKYGT419
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0344KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0344PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0344SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0344RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0344AIVVDPVHGYKKYGT419
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0346KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0346PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0346SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0346RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0346AIVVDPVHGYKKYGT419
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0348KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0348PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0348SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0348RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0348AIVVDPVHGYKKYGT419
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0350KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0350PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0350SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0350RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0350AIVVDPVHGYKKYGT419
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0352KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0352PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0352SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0352RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0352AIVVDPVHGYKKYGT419
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0354KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0354PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0354SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0354RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0354AIVVDPVHGYKKYGT419
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0422PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0422KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0422SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0422RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0434PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0434KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0435PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0435KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0444PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0444KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0466PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0466KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0466SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0466RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0472PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0472KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0812PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0812KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0819PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0819KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0819SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0825PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0825KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0825SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0825RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0834PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0834KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0834SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0840KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-0840PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1107PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1107KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1107SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1107RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1113PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1113KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1114PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1114KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1114SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1120PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1120KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1120SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1121PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1121KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1134PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1134KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1148PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1148KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1157PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1168PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1168KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1173PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1173KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1179PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1179KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1179SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1179RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1182PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1182KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1186PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1186KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1201PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1201KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1203PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1203KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1203SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1204PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1204KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1205PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1205KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1206PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1206KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1207PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1207KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1208PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1208KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1209PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1209KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1210PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1210KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1211PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1211KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1212PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1212KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1212SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1213PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1213KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1214PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1214KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1215PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1215KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1217PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1217KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1218PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1218KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1219PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1219KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1220PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1220KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1220SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1220RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1221PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1221KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1221SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1221RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1222PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1222KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1222SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1222RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1223PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1223KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1302PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1302KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1302SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1304PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1304KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1308PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1308KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1309PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1309KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-13101KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-13101PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1310KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1310PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1316PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1316KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1319PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1323PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1323KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1323SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1327PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1327KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1329PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1329KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1331PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1331KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1331SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1331RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1332PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1332KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1333KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1333PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1333SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1334PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1334KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1334SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1336PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1336KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1336SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1337PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1337KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1338PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1338KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1338SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1339PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1339KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1339SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1341PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1341KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1341SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1341RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1343PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1343KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1344PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1344KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1348PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1348KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1353PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1354PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1354KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1358PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1358KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1361PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1361KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1365PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1365KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1365SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1367PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1367KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1370PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1370KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1371PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1371KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1371SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1372PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1372KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1373PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1373KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1373SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1374PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1374KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1374SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1376PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1376KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1377PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1377KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1377SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1381PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1381KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1381SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1384PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1384KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1385PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1385KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1386PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1386KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1389PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1389KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1393PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1393KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1394PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1394KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1394SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1394RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1396PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1396KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1396SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1396RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1397PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1397KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1397SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1399PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1399KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1399SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1402PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1402KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1402SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1404KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1404PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1406PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1406KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1406SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1406RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1409PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1409KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1409SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1411PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1411KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1413PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1413KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1413SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1416PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1416KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1417PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1417KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1418PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1418KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1419PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1419KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1419SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1419RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1420PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1420KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1420SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1420RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1421PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1421KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1421SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1421RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1424PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1424KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1424SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1424RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1428PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1428KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1429PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1429KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1429RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1429SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1430PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1430KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1431PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1431KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1431SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1432PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1432KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1433PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1433KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1434PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1434KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1437PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1437KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1437SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1437RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1438PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1438KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1438SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1439KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1439PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1441PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1441KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1441SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1443PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1443KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1446PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1446KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1446SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1446RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1447PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1447KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1447SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1447RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1448PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1448KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1448SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1448RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1449PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1449KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1449SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1449RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1450PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1450KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1450SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1450RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1451PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1451KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1452PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1452KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1452RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1452SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1455PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1455KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1457PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1457KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1461KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1461PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1465PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1465KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1468PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1468KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1469PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1469KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1470KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1470PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1471KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1474PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1474KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1476PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1476KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1476SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1476RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1476AIVVDPVHGYKKYGT419
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1479PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1479KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1479SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1479RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1479AIVVDPVHGYKKYGT419
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1480PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1480KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1480SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1480RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1481PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1481KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1482KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1482PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1482SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1483PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1483KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1483SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1483RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1489PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1489KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1493PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1493KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1493SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1494PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1494KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1494SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1495PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1495KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1495SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1498PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1498KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1499PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1499KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1525PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1525KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1525SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB1-1525RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0101KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0101PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0101SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0101RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0104KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0104PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0104SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0104RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0105KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0105PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0105SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0105RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0108KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0108PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0108SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0108RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0109PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0109KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0109SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0109RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0111KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0111PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0111SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0111RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0112KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0112PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0112SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0112RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0113KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0113PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0113SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0113RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0114KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0114PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0114SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0114RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0114AIVVDPVHGYKKYGT419
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0201PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0201KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0201SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0204PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0204KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0204SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0204RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0205PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0205KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0209PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0209KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0213PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0213KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0214PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0214KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0216PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0216KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0219PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0219KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0221PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0221KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0222PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0222KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0224PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0224KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0224SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0301PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0301KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0301SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0303PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0303KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0303SKPRAIVVDPVHGYK015
LDLR-ZGLP1chr1911224437chr19104158831168DRB3-0303RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB4-0104PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB4-0104KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB5-0106PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB5-0106KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB5-0106RAIVVDPVHGYKKYG318
LDLR-ZGLP1chr1911224437chr19104158831168DRB5-0111PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB5-0111KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB5-0205PRAIVVDPVHGYKKY217
LDLR-ZGLP1chr1911224437chr19104158831168DRB5-0205KPRAIVVDPVHGYKK116
LDLR-ZGLP1chr1911224437chr19104158831168DRB5-0205RAIVVDPVHGYKKYG318

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Fusion breakpoint peptide structures of LDLR-ZGLP1

check button3D structures of the fusion breakpoint peptide of 14AA sequence that have potential fusion neoantigens
* The minimum length of the amino acid sequence in RoseTTAFold is 14AA. Here, we predicted the 14AA fusion protein breakpoint sequence not the fusion neoantigen peptide, which is shorter than 14 AA.
File nameBPseqHgeneTgeneHchrHbpTchrTbpAAlen
10342VVDPVHGYKKYGTRLDLRZGLP1chr1911224437chr19104158831168

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Filtering FusionNeoAntigens Through Checking the Interaction with HLAs in 3D of LDLR-ZGLP1

check buttonVirtual screening between 25 HLAs (from PDB) and FusionNeoAntigens
* We used Glide to predict the interaction between HLAs and neoantigens.
HLA allelePDB IDFile nameBPseqDocking scoreGlide score
HLA-B14:023BVN10342VVDPVHGYKKYGTR-7.15543-7.26883
HLA-B14:023BVN10342VVDPVHGYKKYGTR-4.77435-5.80965
HLA-B52:013W3910342VVDPVHGYKKYGTR-6.80875-6.92215
HLA-B52:013W3910342VVDPVHGYKKYGTR-4.20386-5.23916
HLA-A11:014UQ210342VVDPVHGYKKYGTR-7.5194-8.5547
HLA-A11:014UQ210342VVDPVHGYKKYGTR-6.9601-7.0735
HLA-A24:025HGA10342VVDPVHGYKKYGTR-7.52403-7.63743
HLA-A24:025HGA10342VVDPVHGYKKYGTR-5.82433-6.85963
HLA-B27:056PYJ10342VVDPVHGYKKYGTR-3.28285-4.31815
HLA-B44:053DX810342VVDPVHGYKKYGTR-5.91172-6.94702
HLA-B44:053DX810342VVDPVHGYKKYGTR-4.24346-4.35686
HLA-B35:011A1N10342VVDPVHGYKKYGTR-5.9251-6.0385
HLA-B35:011A1N10342VVDPVHGYKKYGTR-4.80237-5.83767

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Vaccine Design for the FusionNeoAntigens of LDLR-ZGLP1

check button mRNA and peptide sequences of FusionNeoAntigens that have potential interaction with HLA-Is.
Fusion geneHchrHbpTchrTbpStart in +/-13AAEnd in +/-13AAFusionNeoAntigen peptide sequenceFusionNeoAntigen RNA sequence
LDLR-ZGLP1chr1911224437chr1910415883314RAIVVDPVHGYAAGGGCCATCGTGGTGGATCCTGTTCATGGGTA
LDLR-ZGLP1chr1911224437chr1910415883414AIVVDPVHGYGGCCATCGTGGTGGATCCTGTTCATGGGTA
LDLR-ZGLP1chr1911224437chr1910415883514IVVDPVHGYCATCGTGGTGGATCCTGTTCATGGGTA
LDLR-ZGLP1chr1911224437chr1910415883516IVVDPVHGYKKCATCGTGGTGGATCCTGTTCATGGGTACAAGAA
LDLR-ZGLP1chr1911224437chr1910415883615VVDPVHGYKCGTGGTGGATCCTGTTCATGGGTACAA
LDLR-ZGLP1chr1911224437chr1910415883817DPVHGYKKYGGATCCTGTTCATGGGTACAAGAAATA

check button mRNA and peptide sequences of FusionNeoAntigens that have potential interaction with HLA-IIs.
Fusion geneHchrHbpTchrTbpStart in +/-13AAEnd in +/-13AAFusionNeoAntigen peptideFusionNEoAntigen RNA sequence
LDLR-ZGLP1chr1911224437chr1910415883015SKPRAIVVDPVHGYKCTCCAAGCCAAGGGCCATCGTGGTGGATCCTGTTCATGGGTACAA
LDLR-ZGLP1chr1911224437chr1910415883116KPRAIVVDPVHGYKKCAAGCCAAGGGCCATCGTGGTGGATCCTGTTCATGGGTACAAGAA
LDLR-ZGLP1chr1911224437chr1910415883217PRAIVVDPVHGYKKYGCCAAGGGCCATCGTGGTGGATCCTGTTCATGGGTACAAGAAATA
LDLR-ZGLP1chr1911224437chr1910415883318RAIVVDPVHGYKKYGAAGGGCCATCGTGGTGGATCCTGTTCATGGGTACAAGAAATACGG
LDLR-ZGLP1chr1911224437chr1910415883419AIVVDPVHGYKKYGTGGCCATCGTGGTGGATCCTGTTCATGGGTACAAGAAATACGGCAC

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Information of the samples that have these potential fusion neoantigens of LDLR-ZGLP1

check button These samples were reported as having these fusion breakpoints. For individual breakpoints, we checked the open reading frames considering multiple gene isoforms and chose the in-frame fusion genes only. Then, we made fusion protein sequences and predicted the fusion neoantigens. These fusion-positive samples may have these potential fusion neoantigens.
Cancer typeFusion geneHchrHbpHenstTchrTbpTenstSample
ACCLDLR-ZGLP1chr1911224437ENST00000455727chr1910415883ENST00000403352TCGA-OR-A5JP-01A

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Potential target of CAR-T therapy development for LDLR-ZGLP1

check button Predicted 3D structure. We used RoseTTAFold.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, to provide the retention of the transmembrane domain, we only show the protein feature retention information of those transmembrane features


* Minus value of BPloci means that the break point is located before the CDS.
- In-frame and retained 'Transmembrane'.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

check button Subcellular localization prediction of the transmembrane domain retained fusion proteins
* We used DeepLoc 1.0. The order of the X-axis of the barplot is as follows: Entry_ID, Localization, Type, Nucleus, Cytoplasm, Extracellular, Mitochondrion, Cell_membrane, Endoplasmic_reticulum, Plastid, Golgi.apparatus, Lysosome.Vacuole, Peroxisome. Y-axis is the output score of DeepLoc. Clicking the image will open a new tab with a large image.
HgeneHchrHbpHenstTgeneTchrTbpTenstDeepLoc result

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Related Drugs to LDLR-ZGLP1

check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

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Related Diseases to LDLR-ZGLP1

check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource