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Center for Computational Systems Medicine
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Fusion Gene and Fusion Protein Summary

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Fusion Amino Acid Sequences (multiple BPs and multiple gene isoforms)

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Fusion Protein Breakpoint Sequences - (for the Screening of the FusionNeoAntigens)

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Potential FusionNeoAntigens in HLA I - (netMHCpan v4.1 + deepHLApan v1.1)

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Potential FusionNeoAntigens in HLA II - (netMHCIIpan v4.1)

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Fusion Breakpoint 14 AA Peptide Structure - (RoseTTAFold)

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Filtering FusionNeoAntigens Through Checking the Interaction with HLAs in 3D - (Glide)

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Vaccine Design for the FusionNeoAntigens (RNA/protein sequences)

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Potential target of CAR-T therapy development

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Information on the samples that have these potential fusion neoantigens

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Fusion Protein Targeting Drugs - (Manual Curation)

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Fusion Protein Related diseases - (Manual Curation)

Fusion Protein:PHKB-VRK2

Fusion Gene and Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: PHKB-VRK2
FusionPDB ID: 64944
FusionGDB2.0 ID: 64944
HgeneTgene
Gene symbol

PHKB

VRK2

Gene ID

5257

7444

Gene namephosphorylase kinase regulatory subunit betaVRK serine/threonine kinase 2
Synonyms--
Cytomap

16q12.1

2p16.1

Type of geneprotein-codingprotein-coding
Descriptionphosphorylase b kinase regulatory subunit betaphosphorylase kinase beta-subunitphosphorylase kinase subunit betaphosphorylase kinase, betaserine/threonine-protein kinase VRK2vaccinia related kinase 2vaccinia virus B1R-related kinase 2
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST idsENST00000567402, ENST00000299167, 
ENST00000323584, ENST00000455779, 
ENST00000566044, 
ENST00000417641, 
ENST00000435505, ENST00000340157, 
ENST00000412104, ENST00000440705, 
ENST00000478687, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score11 X 11 X 8=9684 X 3 X 3=36
# samples 114
** MAII scorelog2(11/968*10)=-3.13750352374993
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(4/36*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Fusion gene context

PubMed: PHKB [Title/Abstract] AND VRK2 [Title/Abstract] AND fusion [Title/Abstract]

Fusion neoantigen context

PubMed: PHKB [Title/Abstract] AND VRK2 [Title/Abstract] AND neoantigen [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)PHKB(47531399)-VRK2(58313473), # samples:1
Anticipated loss of major functional domain due to fusion event.PHKB-VRK2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
PHKB-VRK2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
PHKB-VRK2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
PHKB-VRK2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneVRK2

GO:0046777

protein autophosphorylation

14645249|16704422



check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr16:47531399/chr2:58313473)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonRetention analysis results of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features, are available here.

check buttonFusion gene breakpoints across PHKB (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across VRK2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


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Fusion Amino Acid Sequences


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)
ENST00000566044PHKBchr1647531399+ENST00000435505VRK2chr258313473+17793341891604471
ENST00000566044PHKBchr1647531399+ENST00000417641VRK2chr258313473+18323341891268359
ENST00000455779PHKBchr1647531399+ENST00000435505VRK2chr258313473+17753301851600471
ENST00000455779PHKBchr1647531399+ENST00000417641VRK2chr258313473+18283301851264359
ENST00000299167PHKBchr1647531399+ENST00000435505VRK2chr258313473+1636191251461478
ENST00000299167PHKBchr1647531399+ENST00000417641VRK2chr258313473+1689191251125366
ENST00000323584PHKBchr1647531399+ENST00000435505VRK2chr258313473+1635190241460478
ENST00000323584PHKBchr1647531399+ENST00000417641VRK2chr258313473+1688190241124366

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000566044ENST00000435505PHKBchr1647531399+VRK2chr258313473+0.0002463410.99975365
ENST00000566044ENST00000417641PHKBchr1647531399+VRK2chr258313473+0.0002962110.9997037
ENST00000455779ENST00000435505PHKBchr1647531399+VRK2chr258313473+0.0002463060.99975365
ENST00000455779ENST00000417641PHKBchr1647531399+VRK2chr258313473+0.0002919170.9997081
ENST00000299167ENST00000435505PHKBchr1647531399+VRK2chr258313473+0.0003268470.9996731
ENST00000299167ENST00000417641PHKBchr1647531399+VRK2chr258313473+0.0003632510.99963677
ENST00000323584ENST00000435505PHKBchr1647531399+VRK2chr258313473+0.000325270.9996748
ENST00000323584ENST00000417641PHKBchr1647531399+VRK2chr258313473+0.0003613520.9996387

check button Predicted full-length fusion amino acid sequences. For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among all the predicted ones.

Get the fusion protein sequences from here.

Fusion protein sequence information is available in the fasta format.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

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Fusion Protein Breakpoint Sequences for PHKB-VRK2

check button +/-13 AA sequence from the breakpoints of the fusion protein sequences.
HgeneHchrHbpTgeneTchrTbpLength(fusion protein)BP in fusion proteinPeptide
PHKBchr1647531399VRK2chr25831347319055ETLWDKLDHYYRIVKKWIERKQLDYL
PHKBchr1647531399VRK2chr25831347319155ETLWDKLDHYYRIVKKWIERKQLDYL
PHKBchr1647531399VRK2chr25831347333048ETLWDKLDHYYRIVKKWIERKQLDYL
PHKBchr1647531399VRK2chr25831347333448ETLWDKLDHYYRIVKKWIERKQLDYL

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Potential FusionNeoAntigen Information of PHKB-VRK2 in HLA I

check button Multiple sequence alignments of the potential FusionNeoAntigens per fusion breakpoints. If the MSA is empty, then it means that there were predicted fusion neoantigens in this fusion breakpoint, but those predicted fusion neoantigens were not across the breakpoint, which is not fusion-specific.
PHKB-VRK2_47531399_58313473.msa

check button Potential FusionNeoAntigen Information
* We used NetMHCpan v4.1 (%rank<0.5) and deepHLApan v1.1 (immunogenic score>0.5)
Fusion geneHchrHbpTgeneTchrTbpHLA IFusionNeoAntigen peptideBinding scoreImmunogenic scoreNeoantigen start (at BP 13)Neoantigen end (at BP 13)
PHKB-VRK2chr1647531399chr258313473191HLA-A30:08IVKKWIERK0.98730.59841221
PHKB-VRK2chr1647531399chr258313473191HLA-A02:60KLDHYYRIV0.97260.5631514
PHKB-VRK2chr1647531399chr258313473191HLA-A02:11KLDHYYRIV0.97030.5716514
PHKB-VRK2chr1647531399chr258313473191HLA-A32:13HYYRIVKKW0.96430.6409817
PHKB-VRK2chr1647531399chr258313473191HLA-A02:13KLDHYYRIV0.94640.597514
PHKB-VRK2chr1647531399chr258313473191HLA-A02:35KLDHYYRIV0.86670.5959514
PHKB-VRK2chr1647531399chr258313473191HLA-A02:07KLDHYYRIV0.96970.6111514
PHKB-VRK2chr1647531399chr258313473191HLA-C07:05HYYRIVKKW0.02740.7323817
PHKB-VRK2chr1647531399chr258313473191HLA-C07:10HYYRIVKKW0.00850.7339817
PHKB-VRK2chr1647531399chr258313473191HLA-A30:01IVKKWIERK0.98670.66611221
PHKB-VRK2chr1647531399chr258313473191HLA-A32:01HYYRIVKKW0.94190.6563817

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Potential FusionNeoAntigen Information of PHKB-VRK2 in HLA II

check button Multiple sequence alignments of the potential FusionNeoAntigens per fusion breakpoints. If the MSA is empty, then it means that there were predicted fusion neoantigens in this fusion breakpoint, but those predicted fusion neoantigens were not across the breakpoint, which is not fusion-specific.
PHKB-VRK2_47531399_58313473.msa

check button Potential FusionNeoAntigen Information
* We used NetMHCIIpan v4.1 (%rank<0.5).
Fusion geneHchrHbpTgeneTchrTbpHLA IIFusionNeoAntigen peptideNeoantigen start (at BP 13)Neoantigen end (at BP 13)
PHKB-VRK2chr1647531399chr258313473191DRB1-0801DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-0801LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-0801KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-0801HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-0802DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-0802LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-0802KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-0802HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-0803DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-0803LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-0803KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-0803HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-0803DKLDHYYRIVKKWIE419
PHKB-VRK2chr1647531399chr258313473191DRB1-0805DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-0805LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-0805KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-0805HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-0806DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-0807DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-0807LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-0807KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-0807HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-0808DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-0808LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-0808KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-0808HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-0809DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-0809LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-0809KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-0809HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-0810DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-0811DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-0811LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-0811KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-0811HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-0812DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-0813DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-0813LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-0813KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-0813HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-0814DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-0814LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-0814KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-0814HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-0814DKLDHYYRIVKKWIE419
PHKB-VRK2chr1647531399chr258313473191DRB1-0815DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-0815LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-0815KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-0815HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-0816DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-0816LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-0816KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-0816HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-0818DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-0818LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-0818KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-0818HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-0818DKLDHYYRIVKKWIE419
PHKB-VRK2chr1647531399chr258313473191DRB1-0819DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-0819LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-0819KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-0821DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-0821LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-0821KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-0821HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-0822DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-0823DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-0823LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-0823KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-0823HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-0823DKLDHYYRIVKKWIE419
PHKB-VRK2chr1647531399chr258313473191DRB1-0824DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-0824LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-0824KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-0824HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-0825DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-0825LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-0825KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-0826DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-0826LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-0826KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-0826HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-0827DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-0827LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-0827KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-0827HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-0827DKLDHYYRIVKKWIE419
PHKB-VRK2chr1647531399chr258313473191DRB1-0829DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-0829LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-0829KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-0829HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-0829DKLDHYYRIVKKWIE419
PHKB-VRK2chr1647531399chr258313473191DRB1-0830DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-0830LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-0830KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-0830HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-0832DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-0832LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-0832KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-0832HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-0833DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-0833LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-0833KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-0833HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-0833DKLDHYYRIVKKWIE419
PHKB-VRK2chr1647531399chr258313473191DRB1-0834DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-0834LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-0834KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-0835DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-0835LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-0835KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-0835HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-0835DKLDHYYRIVKKWIE419
PHKB-VRK2chr1647531399chr258313473191DRB1-0836DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-0836LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-0836KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-0836HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-0836DKLDHYYRIVKKWIE419
PHKB-VRK2chr1647531399chr258313473191DRB1-0837DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-0837LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-0837KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-0837HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-0837DKLDHYYRIVKKWIE419
PHKB-VRK2chr1647531399chr258313473191DRB1-0838DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-0838LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-0838KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-0838HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-0838DKLDHYYRIVKKWIE419
PHKB-VRK2chr1647531399chr258313473191DRB1-0839DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-0839LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-0839KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-0839HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-0840DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-0840LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-0840KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-0840HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1101DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1101LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1101HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1101KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1105DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1105LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1105KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1105HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1108DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1108LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1108KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1108HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1109DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1109LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1109HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1109KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1110DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1110LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1110HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1110KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1111DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1111LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1111HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1111KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1112DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1112LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1112HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1112KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1114DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1114LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1115DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1115LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1115HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1115KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1119DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1119LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1119KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1119HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1120DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1120LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1124DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1124LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1124HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1124KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1127DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1127LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1127HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1127KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1128DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1128LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1128HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1128KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1129DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1129LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1129HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1129KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1130DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1130LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1131DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1131LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1131KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1131HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1132DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1132LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1132HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1132KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1133DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1133LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1133HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1133KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1137DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1137LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1137KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1137HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1139DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1139LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1139HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1139KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1145DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1145LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1145KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1145HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1149DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1149LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1149HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1149KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1151DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1151LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1151HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1151KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1153DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1153LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1154DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1154LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1161DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1161LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1161HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1161KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1162DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1162LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1162HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1162KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1164DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1164LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1164KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1164HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1166DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1166LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1166HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1166KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1168DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1168LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1169DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1169LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1169KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1172DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1172LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1172HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1172KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1173DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1173LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1173KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1173HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1174DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1174LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1174HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1174KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1175DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1175LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1175HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1175KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1179DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1179LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1180DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1180LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1180HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1180KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1181DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1181LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1181HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1182DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1182LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1182KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1186DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1186LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1187DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1187LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1187HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1187KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1190DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1190LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1190HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1190KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1191DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1191LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1191HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1193DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1193LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1194DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1194LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1194HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1194KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1195DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1195LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1195HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1195KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1196DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1196LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1196HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1196KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1216DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1216LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1222DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1302DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1302LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1303DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1303LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1303KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1303HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1305DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1305LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1305HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1305KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1307DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1307LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1307KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1307HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-13100DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-13100LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-13100KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-13100HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-13101DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-13101LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-13101KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-13101HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1310DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1310LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1310KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1310HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1312DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1312LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1312KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1312HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1313DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1313LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1313KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1313HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1314DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1314LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1314HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1314KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1316DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1316LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1321DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1321LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1321KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1321HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1323DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1323LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1326DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1326LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1326HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1326KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1329DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1329LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1330DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1330LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1330KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1330HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1330DKLDHYYRIVKKWIE419
PHKB-VRK2chr1647531399chr258313473191DRB1-1331DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1331LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1331KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1333DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1333LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1333KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1333HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1334DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1334LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1336DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1336LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1337DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1337LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1337HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1337KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1338DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1338LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1338KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1338HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1339DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1339LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1341DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1341LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1346DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1346LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1346KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1346HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1347DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1347LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1347KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1347HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1349DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1349LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1349KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1349HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1350DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1350LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1350HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1350KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1355DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1355LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1355KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1355HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1356DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1356LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1356KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1356HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1358DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1360DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1360LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1360KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1360HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1362DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1362LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1362HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1362KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1363DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1363LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1363HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1363KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1365DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1365LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1365KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1365HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1366DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1366LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1366KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1366HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1367DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1367LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1373DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1373LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1374DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1374LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1382DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1382LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1382KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1382HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1385DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1385LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1385KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1385HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1386DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1386LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1386KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1388DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1388LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1388KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1388HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1390DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1390LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1390KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1390HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1395DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1395LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1395KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1395HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1396DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1396LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1397DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1397LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1399DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1399LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1402DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1402LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1403DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1403LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1403HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1403KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1407DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1407LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1407KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1409DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1409LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1413DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1413LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1413KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1413HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1414DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1414LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1414KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1414HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1419DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1422DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1422LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1422KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1422HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1424DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1424LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1425DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1425LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1425KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1425HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1427DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1427LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1427HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1427KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1430DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1430LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1430KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1430HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1436DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1436LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1436KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1436HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1440DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1440LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1440HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1440KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1441DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1441LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1442DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1442LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1442KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1442HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1444DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1444LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1444KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1444HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1446DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1446LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1447DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1449DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1449LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1449KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1451DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1451LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1451KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1451HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1453DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1453LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1453KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1453HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1463DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1463LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1463KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1463HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1463DKLDHYYRIVKKWIE419
PHKB-VRK2chr1647531399chr258313473191DRB1-1467DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1467LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1467HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1467KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1468DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1468LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1468KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1468HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1469DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1469LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1469KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1469HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1473DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1473LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1473KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1477DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1477LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1477HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1477KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1478DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1485DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1485LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1485KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1485HYYRIVKKWIERKQL823
PHKB-VRK2chr1647531399chr258313473191DRB1-1485DKLDHYYRIVKKWIE419
PHKB-VRK2chr1647531399chr258313473191DRB1-1489DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1489LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1493DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1493LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1493KLDHYYRIVKKWIER520
PHKB-VRK2chr1647531399chr258313473191DRB1-1494DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1494LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1498DHYYRIVKKWIERKQ722
PHKB-VRK2chr1647531399chr258313473191DRB1-1498LDHYYRIVKKWIERK621
PHKB-VRK2chr1647531399chr258313473191DRB1-1498HYYRIVKKWIERKQL823

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Fusion breakpoint peptide structures of PHKB-VRK2

check button3D structures of the fusion breakpoint peptide of 14AA sequence that have potential fusion neoantigens
* The minimum length of the amino acid sequence in RoseTTAFold is 14AA. Here, we predicted the 14AA fusion protein breakpoint sequence not the fusion neoantigen peptide, which is shorter than 14 AA.
File nameBPseqHgeneTgeneHchrHbpTchrTbpAAlen
4841LDHYYRIVKKWIERPHKBVRK2chr1647531399chr258313473191

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Filtering FusionNeoAntigens Through Checking the Interaction with HLAs in 3D of PHKB-VRK2

check buttonVirtual screening between 25 HLAs (from PDB) and FusionNeoAntigens
* We used Glide to predict the interaction between HLAs and neoantigens.
HLA allelePDB IDFile nameBPseqDocking scoreGlide score
HLA-B14:023BVN4841LDHYYRIVKKWIER-7.9962-8.1096
HLA-B14:023BVN4841LDHYYRIVKKWIER-5.70842-6.74372
HLA-B52:013W394841LDHYYRIVKKWIER-6.83737-6.95077
HLA-B52:013W394841LDHYYRIVKKWIER-4.4836-5.5189
HLA-A11:014UQ24841LDHYYRIVKKWIER-10.0067-10.1201
HLA-A11:014UQ24841LDHYYRIVKKWIER-9.03915-10.0745
HLA-A24:025HGA4841LDHYYRIVKKWIER-6.56204-6.67544
HLA-A24:025HGA4841LDHYYRIVKKWIER-5.42271-6.45801
HLA-B44:053DX84841LDHYYRIVKKWIER-7.85648-8.89178
HLA-B44:053DX84841LDHYYRIVKKWIER-5.3978-5.5112
HLA-A02:016TDR4841LDHYYRIVKKWIER-3.37154-4.40684

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Vaccine Design for the FusionNeoAntigens of PHKB-VRK2

check button mRNA and peptide sequences of FusionNeoAntigens that have potential interaction with HLA-Is.
Fusion geneHchrHbpTchrTbpStart in +/-13AAEnd in +/-13AAFusionNeoAntigen peptide sequenceFusionNeoAntigen RNA sequence
PHKB-VRK2chr1647531399chr2583134731221IVKKWIERKTTGTCAAAAAGTGGATAGAACGCAAAC
PHKB-VRK2chr1647531399chr258313473514KLDHYYRIVAGTTGGACCATTATTACAGAATTGTCA
PHKB-VRK2chr1647531399chr258313473817HYYRIVKKWATTATTACAGAATTGTCAAAAAGTGGA

check button mRNA and peptide sequences of FusionNeoAntigens that have potential interaction with HLA-IIs.
Fusion geneHchrHbpTchrTbpStart in +/-13AAEnd in +/-13AAFusionNeoAntigen peptideFusionNEoAntigen RNA sequence
PHKB-VRK2chr1647531399chr258313473419DKLDHYYRIVKKWIEATAAGTTGGACCATTATTACAGAATTGTCAAAAAGTGGATAGAAC
PHKB-VRK2chr1647531399chr258313473520KLDHYYRIVKKWIERAGTTGGACCATTATTACAGAATTGTCAAAAAGTGGATAGAACGCA
PHKB-VRK2chr1647531399chr258313473621LDHYYRIVKKWIERKTGGACCATTATTACAGAATTGTCAAAAAGTGGATAGAACGCAAAC
PHKB-VRK2chr1647531399chr258313473722DHYYRIVKKWIERKQACCATTATTACAGAATTGTCAAAAAGTGGATAGAACGCAAACAAC
PHKB-VRK2chr1647531399chr258313473823HYYRIVKKWIERKQLATTATTACAGAATTGTCAAAAAGTGGATAGAACGCAAACAACTTG

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Information of the samples that have these potential fusion neoantigens of PHKB-VRK2

check button These samples were reported as having these fusion breakpoints. For individual breakpoints, we checked the open reading frames considering multiple gene isoforms and chose the in-frame fusion genes only. Then, we made fusion protein sequences and predicted the fusion neoantigens. These fusion-positive samples may have these potential fusion neoantigens.
Cancer typeFusion geneHchrHbpHenstTchrTbpTenstSample
ESCAPHKB-VRK2chr1647531399ENST00000299167chr258313473ENST00000417641TCGA-IG-A51D

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Potential target of CAR-T therapy development for PHKB-VRK2

check button Predicted 3D structure. We used RoseTTAFold.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, to provide the retention of the transmembrane domain, we only show the protein feature retention information of those transmembrane features


* Minus value of BPloci means that the break point is located before the CDS.
- In-frame and retained 'Transmembrane'.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneVRK2chr16:47531399chr2:58313473ENST00000340157313487_5070509.0TransmembraneHelical%3B Anchor for type IV membrane protein
TgeneVRK2chr16:47531399chr2:58313473ENST00000412104314487_5070511.6666666666667TransmembraneHelical%3B Anchor for type IV membrane protein
TgeneVRK2chr16:47531399chr2:58313473ENST00000417641516487_5070508.3333333333333TransmembraneHelical%3B Anchor for type IV membrane protein
TgeneVRK2chr16:47531399chr2:58313473ENST00000435505616487_5070509.0TransmembraneHelical%3B Anchor for type IV membrane protein
TgeneVRK2chr16:47531399chr2:58313473ENST00000440705313487_5070486.0TransmembraneHelical%3B Anchor for type IV membrane protein

check button Subcellular localization prediction of the transmembrane domain retained fusion proteins
* We used DeepLoc 1.0. The order of the X-axis of the barplot is as follows: Entry_ID, Localization, Type, Nucleus, Cytoplasm, Extracellular, Mitochondrion, Cell_membrane, Endoplasmic_reticulum, Plastid, Golgi.apparatus, Lysosome.Vacuole, Peroxisome. Y-axis is the output score of DeepLoc. Clicking the image will open a new tab with a large image.
HgeneHchrHbpHenstTgeneTchrTbpTenstDeepLoc result

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Related Drugs to PHKB-VRK2

check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

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Related Diseases to PHKB-VRK2

check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource