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Center for Computational Systems Medicine level2
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Fusion Gene Summary

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Fusion Gene Sample Information

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Fusion ORF Analysis

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Fusion Amino Acid Sequences

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Fusion Protein Functional Features

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Fusion Protein Structure

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pLDDT scores

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Ramachandran Plot of Fusion Protein Structure

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Fusion Protein-Protein Interaction

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Related drugs with this fusion protein

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Related disease with this fusion protein

Fusion Protein:CHST11-TXNRD1

Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: CHST11-TXNRD1
FusionPDB ID: 16692
FusionGDB2.0 ID: 16692
HgeneTgene
Gene symbol

CHST11

TXNRD1

Gene ID

50515

7296

Gene namecarbohydrate sulfotransferase 11thioredoxin reductase 1
SynonymsC4ST|C4ST-1|C4ST1|HSA269537|OCBMDGRIM-12|TR|TR1|TRXR1|TXNR
Cytomap

12q23.3

12q23.3

Type of geneprotein-codingprotein-coding
Descriptioncarbohydrate sulfotransferase 11C4S-1IgH/CHST11 fusioncarbohydrate (chondroitin 4) sulfotransferase 11chondroitin 4-O-sulfotransferase 1thioredoxin reductase 1, cytoplasmicKM-102-derived reductase-like factorgene associated with retinoic and IFN-induced mortality 12 proteingene associated with retinoic and interferon-induced mortality 12 proteinoxidoreductasetestis tissue sperm-bindi
Modification date2020031320200313
UniProtAcc

Q9NPF2

.
Ensembl transtripts involved in fusion geneENST idsENST00000303694, ENST00000546689, 
ENST00000547956, ENST00000549260, 
ENST00000550711, 		ENST00000378070, 
ENST00000397736, ENST00000427956, 
ENST00000526950, ENST00000526006, 
ENST00000354940, ENST00000388854, 
ENST00000429002, ENST00000503506, 
ENST00000524698, ENST00000525566, 
ENST00000526390, ENST00000526691, 
ENST00000529546, ENST00000542918, 
ENST00000540716, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score13 X 8 X 6=62411 X 11 X 4=484
# samples 1512
** MAII scorelog2(15/624*10)=-2.05658352836637
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(12/484*10)=-2.01197264166608
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)

PubMed: CHST11 [Title/Abstract] AND TXNRD1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)CHST11(104995769)-TXNRD1(104732917), # samples:2
TXNRD1(104682818)-CHST11(104995683), # samples:1
TXNRD1(104733051)-CHST11(104995683), # samples:1
TXNRD1(104733050)-CHST11(104858480), # samples:1
Anticipated loss of major functional domain due to fusion event.TXNRD1-CHST11 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
TXNRD1-CHST11 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
CHST11-TXNRD1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CHST11-TXNRD1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
CHST11-TXNRD1 seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
CHST11-TXNRD1 seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
CHST11-TXNRD1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
CHST11-TXNRD1 seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
TXNRD1-CHST11 seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
TXNRD1-CHST11 seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
TXNRD1-CHST11 seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF.
TXNRD1-CHST11 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCHST11

GO:0030206

chondroitin sulfate biosynthetic process

11056388


check buttonFusion gene breakpoints across CHST11 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across TXNRD1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


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Fusion Gene Sample Information

check buttonFusion gene information from FusionGDB2.0.
check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4HNSCTCGA-P3-A6T4-01ACHST11chr12

104995769

-TXNRD1chr12

104732917

+
ChimerDB4HNSCTCGA-P3-A6T4CHST11chr12

104995769

+TXNRD1chr12

104732917

+
ChimerDB4HNSCTCGA-P3-A6T4CHST11chr12

104995769

+TXNRD1chr12

104742130

+
ChimerDB4HNSCTCGA-P3-A6T4CHST11chr12

104995769

+TXNRD1chr12

104742131

+


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Fusion ORF Analysis


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000547956CHST11chr12104995769+ENST00000540716TXNRD1chr12104742130+136685015608197
ENST00000549260CHST11chr12104995769+ENST00000540716TXNRD1chr12104742130+11466307310244
ENST00000303694CHST11chr12104995769+ENST00000540716TXNRD1chr12104742130+11596437441248
ENST00000546689CHST11chr12104995769+ENST00000540716TXNRD1chr12104742130+11866705390180
ENST00000547956CHST11chr12104995769+ENST00000525566TXNRD1chr12104732917+291685015608197
ENST00000547956CHST11chr12104995769+ENST00000429002TXNRD1chr12104732917+291085015608197
ENST00000547956CHST11chr12104995769+ENST00000503506TXNRD1chr12104732917+291085015608197
ENST00000547956CHST11chr12104995769+ENST00000526691TXNRD1chr12104732917+291685015608197
ENST00000547956CHST11chr12104995769+ENST00000388854TXNRD1chr12104732917+291085015608197
ENST00000547956CHST11chr12104995769+ENST00000354940TXNRD1chr12104732917+291085015608197
ENST00000547956CHST11chr12104995769+ENST00000526390TXNRD1chr12104732917+290785015608197
ENST00000547956CHST11chr12104995769+ENST00000529546TXNRD1chr12104732917+146185015608197
ENST00000547956CHST11chr12104995769+ENST00000540716TXNRD1chr12104732917+150185015608197
ENST00000547956CHST11chr12104995769+ENST00000524698TXNRD1chr12104732917+127785015608197
ENST00000547956CHST11chr12104995769+ENST00000542918TXNRD1chr12104732917+127785015608197
ENST00000547956CHST11chr12104995769+ENST00000378070TXNRD1chr12104732917+305385015608197
ENST00000547956CHST11chr12104995769+ENST00000397736TXNRD1chr12104732917+291085015608197
ENST00000547956CHST11chr12104995769+ENST00000427956TXNRD1chr12104732917+291085015608197
ENST00000547956CHST11chr12104995769+ENST00000526950TXNRD1chr12104732917+111685015608197
ENST00000549260CHST11chr12104995769+ENST00000525566TXNRD1chr12104732917+269663012827271
ENST00000549260CHST11chr12104995769+ENST00000429002TXNRD1chr12104732917+269063012827271
ENST00000549260CHST11chr12104995769+ENST00000503506TXNRD1chr12104732917+269063012827271
ENST00000549260CHST11chr12104995769+ENST00000526691TXNRD1chr12104732917+269663012827271
ENST00000549260CHST11chr12104995769+ENST00000388854TXNRD1chr12104732917+269063012827271
ENST00000549260CHST11chr12104995769+ENST00000354940TXNRD1chr12104732917+269063012827271
ENST00000549260CHST11chr12104995769+ENST00000526390TXNRD1chr12104732917+268763012827271
ENST00000549260CHST11chr12104995769+ENST00000529546TXNRD1chr12104732917+124163012827271
ENST00000549260CHST11chr12104995769+ENST00000540716TXNRD1chr12104732917+12816308660289
ENST00000549260CHST11chr12104995769+ENST00000524698TXNRD1chr12104732917+10576308660289
ENST00000549260CHST11chr12104995769+ENST00000542918TXNRD1chr12104732917+10576308660289
ENST00000549260CHST11chr12104995769+ENST00000378070TXNRD1chr12104732917+283363012782256
ENST00000549260CHST11chr12104995769+ENST00000397736TXNRD1chr12104732917+269063012827271
ENST00000549260CHST11chr12104995769+ENST00000427956TXNRD1chr12104732917+269063012827271
ENST00000549260CHST11chr12104995769+ENST00000526950TXNRD1chr12104732917+89663012827271
ENST00000303694CHST11chr12104995769+ENST00000525566TXNRD1chr12104732917+270964310840276
ENST00000303694CHST11chr12104995769+ENST00000429002TXNRD1chr12104732917+270364310840276
ENST00000303694CHST11chr12104995769+ENST00000503506TXNRD1chr12104732917+270364310840276
ENST00000303694CHST11chr12104995769+ENST00000526691TXNRD1chr12104732917+270964310840276
ENST00000303694CHST11chr12104995769+ENST00000388854TXNRD1chr12104732917+270364310840276
ENST00000303694CHST11chr12104995769+ENST00000354940TXNRD1chr12104732917+270364310840276
ENST00000303694CHST11chr12104995769+ENST00000526390TXNRD1chr12104732917+270064310840276
ENST00000303694CHST11chr12104995769+ENST00000529546TXNRD1chr12104732917+125464310840276
ENST00000303694CHST11chr12104995769+ENST00000540716TXNRD1chr12104732917+12946438791293
ENST00000303694CHST11chr12104995769+ENST00000524698TXNRD1chr12104732917+10706438791293
ENST00000303694CHST11chr12104995769+ENST00000542918TXNRD1chr12104732917+10706438791293
ENST00000303694CHST11chr12104995769+ENST00000378070TXNRD1chr12104732917+284664310795261
ENST00000303694CHST11chr12104995769+ENST00000397736TXNRD1chr12104732917+270364310840276
ENST00000303694CHST11chr12104995769+ENST00000427956TXNRD1chr12104732917+270364310840276
ENST00000303694CHST11chr12104995769+ENST00000526950TXNRD1chr12104732917+90964310840276
ENST00000546689CHST11chr12104995769+ENST00000525566TXNRD1chr12104732917+27366705390180
ENST00000546689CHST11chr12104995769+ENST00000429002TXNRD1chr12104732917+27306705390180
ENST00000546689CHST11chr12104995769+ENST00000503506TXNRD1chr12104732917+27306705390180
ENST00000546689CHST11chr12104995769+ENST00000526691TXNRD1chr12104732917+27366705390180
ENST00000546689CHST11chr12104995769+ENST00000388854TXNRD1chr12104732917+27306705390180
ENST00000546689CHST11chr12104995769+ENST00000354940TXNRD1chr12104732917+27306705390180
ENST00000546689CHST11chr12104995769+ENST00000526390TXNRD1chr12104732917+27276705390180
ENST00000546689CHST11chr12104995769+ENST00000529546TXNRD1chr12104732917+12816705390180
ENST00000546689CHST11chr12104995769+ENST00000540716TXNRD1chr12104732917+13216705390180
ENST00000546689CHST11chr12104995769+ENST00000524698TXNRD1chr12104732917+10976705851037150
ENST00000546689CHST11chr12104995769+ENST00000542918TXNRD1chr12104732917+10976705851037150
ENST00000546689CHST11chr12104995769+ENST00000378070TXNRD1chr12104732917+28736701043687118
ENST00000546689CHST11chr12104995769+ENST00000397736TXNRD1chr12104732917+27306705390180
ENST00000546689CHST11chr12104995769+ENST00000427956TXNRD1chr12104732917+27306705390180
ENST00000546689CHST11chr12104995769+ENST00000526950TXNRD1chr12104732917+9366705390180
ENST00000547956CHST11chr12104995769+ENST00000540716TXNRD1chr12104742131+136685015608197
ENST00000549260CHST11chr12104995769+ENST00000540716TXNRD1chr12104742131+11466307310244
ENST00000303694CHST11chr12104995769+ENST00000540716TXNRD1chr12104742131+11596437441248
ENST00000546689CHST11chr12104995769+ENST00000540716TXNRD1chr12104742131+11866705390180

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000547956ENST00000540716CHST11chr12104995769+TXNRD1chr12104742130+0.218229860.78177017
ENST00000549260ENST00000540716CHST11chr12104995769+TXNRD1chr12104742130+0.0478707250.95212924
ENST00000303694ENST00000540716CHST11chr12104995769+TXNRD1chr12104742130+0.0666546750.9333453
ENST00000546689ENST00000540716CHST11chr12104995769+TXNRD1chr12104742130+0.37142530.62857467
ENST00000547956ENST00000525566CHST11chr12104995769+TXNRD1chr12104732917+0.252510250.74748975
ENST00000547956ENST00000429002CHST11chr12104995769+TXNRD1chr12104732917+0.240463110.7595369
ENST00000547956ENST00000503506CHST11chr12104995769+TXNRD1chr12104732917+0.240463110.7595369
ENST00000547956ENST00000526691CHST11chr12104995769+TXNRD1chr12104732917+0.252510250.74748975
ENST00000547956ENST00000388854CHST11chr12104995769+TXNRD1chr12104732917+0.240463110.7595369
ENST00000547956ENST00000354940CHST11chr12104995769+TXNRD1chr12104732917+0.240463110.7595369
ENST00000547956ENST00000526390CHST11chr12104995769+TXNRD1chr12104732917+0.241175830.7588241
ENST00000547956ENST00000529546CHST11chr12104995769+TXNRD1chr12104732917+0.262625550.7373745
ENST00000547956ENST00000540716CHST11chr12104995769+TXNRD1chr12104732917+0.263839360.73616064
ENST00000547956ENST00000524698CHST11chr12104995769+TXNRD1chr12104732917+0.27704840.7229516
ENST00000547956ENST00000542918CHST11chr12104995769+TXNRD1chr12104732917+0.27704840.7229516
ENST00000547956ENST00000378070CHST11chr12104995769+TXNRD1chr12104732917+0.21504970.78495026
ENST00000547956ENST00000397736CHST11chr12104995769+TXNRD1chr12104732917+0.240463110.7595369
ENST00000547956ENST00000427956CHST11chr12104995769+TXNRD1chr12104732917+0.240463110.7595369
ENST00000547956ENST00000526950CHST11chr12104995769+TXNRD1chr12104732917+0.36547520.63452476
ENST00000549260ENST00000525566CHST11chr12104995769+TXNRD1chr12104732917+0.0257522240.9742477
ENST00000549260ENST00000429002CHST11chr12104995769+TXNRD1chr12104732917+0.0254929030.97450715
ENST00000549260ENST00000503506CHST11chr12104995769+TXNRD1chr12104732917+0.0254929030.97450715
ENST00000549260ENST00000526691CHST11chr12104995769+TXNRD1chr12104732917+0.0257522240.9742477
ENST00000549260ENST00000388854CHST11chr12104995769+TXNRD1chr12104732917+0.0254929030.97450715
ENST00000549260ENST00000354940CHST11chr12104995769+TXNRD1chr12104732917+0.0254929030.97450715
ENST00000549260ENST00000526390CHST11chr12104995769+TXNRD1chr12104732917+0.0250754470.97492456
ENST00000549260ENST00000529546CHST11chr12104995769+TXNRD1chr12104732917+0.0144527420.9855473
ENST00000549260ENST00000540716CHST11chr12104995769+TXNRD1chr12104732917+0.0163978770.98360205
ENST00000549260ENST00000524698CHST11chr12104995769+TXNRD1chr12104732917+0.0232965670.97670346
ENST00000549260ENST00000542918CHST11chr12104995769+TXNRD1chr12104732917+0.0232965670.97670346
ENST00000549260ENST00000378070CHST11chr12104995769+TXNRD1chr12104732917+0.0284464750.97155356
ENST00000549260ENST00000397736CHST11chr12104995769+TXNRD1chr12104732917+0.0254929030.97450715
ENST00000549260ENST00000427956CHST11chr12104995769+TXNRD1chr12104732917+0.0254929030.97450715
ENST00000549260ENST00000526950CHST11chr12104995769+TXNRD1chr12104732917+0.0183578620.9816421
ENST00000303694ENST00000525566CHST11chr12104995769+TXNRD1chr12104732917+0.0383884050.96161157
ENST00000303694ENST00000429002CHST11chr12104995769+TXNRD1chr12104732917+0.036758680.96324134
ENST00000303694ENST00000503506CHST11chr12104995769+TXNRD1chr12104732917+0.036758680.96324134
ENST00000303694ENST00000526691CHST11chr12104995769+TXNRD1chr12104732917+0.0383884050.96161157
ENST00000303694ENST00000388854CHST11chr12104995769+TXNRD1chr12104732917+0.036758680.96324134
ENST00000303694ENST00000354940CHST11chr12104995769+TXNRD1chr12104732917+0.036758680.96324134
ENST00000303694ENST00000526390CHST11chr12104995769+TXNRD1chr12104732917+0.0372732430.9627268
ENST00000303694ENST00000529546CHST11chr12104995769+TXNRD1chr12104732917+0.0191621330.9808379
ENST00000303694ENST00000540716CHST11chr12104995769+TXNRD1chr12104732917+0.0220583860.9779416
ENST00000303694ENST00000524698CHST11chr12104995769+TXNRD1chr12104732917+0.0302843660.9697157
ENST00000303694ENST00000542918CHST11chr12104995769+TXNRD1chr12104732917+0.0302843660.9697157
ENST00000303694ENST00000378070CHST11chr12104995769+TXNRD1chr12104732917+0.04812120.9518788
ENST00000303694ENST00000397736CHST11chr12104995769+TXNRD1chr12104732917+0.036758680.96324134
ENST00000303694ENST00000427956CHST11chr12104995769+TXNRD1chr12104732917+0.036758680.96324134
ENST00000303694ENST00000526950CHST11chr12104995769+TXNRD1chr12104732917+0.0218727250.97812724
ENST00000546689ENST00000525566CHST11chr12104995769+TXNRD1chr12104732917+0.375941630.62405837
ENST00000546689ENST00000429002CHST11chr12104995769+TXNRD1chr12104732917+0.352944580.64705545
ENST00000546689ENST00000503506CHST11chr12104995769+TXNRD1chr12104732917+0.352944580.64705545
ENST00000546689ENST00000526691CHST11chr12104995769+TXNRD1chr12104732917+0.375941630.62405837
ENST00000546689ENST00000388854CHST11chr12104995769+TXNRD1chr12104732917+0.352944580.64705545
ENST00000546689ENST00000354940CHST11chr12104995769+TXNRD1chr12104732917+0.352944580.64705545
ENST00000546689ENST00000526390CHST11chr12104995769+TXNRD1chr12104732917+0.361415450.63858455
ENST00000546689ENST00000529546CHST11chr12104995769+TXNRD1chr12104732917+0.317539750.6824603
ENST00000546689ENST00000540716CHST11chr12104995769+TXNRD1chr12104732917+0.29838920.70161086
ENST00000546689ENST00000524698CHST11chr12104995769+TXNRD1chr12104732917+0.426629360.5733706
ENST00000546689ENST00000542918CHST11chr12104995769+TXNRD1chr12104732917+0.426629360.5733706
ENST00000546689ENST00000378070CHST11chr12104995769+TXNRD1chr12104732917+0.68257090.3174291
ENST00000546689ENST00000397736CHST11chr12104995769+TXNRD1chr12104732917+0.352944580.64705545
ENST00000546689ENST00000427956CHST11chr12104995769+TXNRD1chr12104732917+0.352944580.64705545
ENST00000546689ENST00000526950CHST11chr12104995769+TXNRD1chr12104732917+0.62798270.37201735
ENST00000547956ENST00000540716CHST11chr12104995769+TXNRD1chr12104742131+0.218229860.78177017
ENST00000549260ENST00000540716CHST11chr12104995769+TXNRD1chr12104742131+0.0478707250.95212924
ENST00000303694ENST00000540716CHST11chr12104995769+TXNRD1chr12104742131+0.0666546750.9333453
ENST00000546689ENST00000540716CHST11chr12104995769+TXNRD1chr12104742131+0.37142530.62857467

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Fusion Amino Acid Sequences


check button For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>16692_16692_1_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000303694_TXNRD1_chr12_104732917_ENST00000354940_length(amino acids)=276AA_BP=211
MERNEVAFGEKGEGPSDSHSGQRSGSGGGTTITARTPAARPATRQRRPPAGSEEAAERRGGGAGARSQRVHASQHFQTNSGTFHTPARAG
GSESGREATPILPLSLAQLCPAPPGLRSARRGPCSCAPGALPGHPGPRSQDKAMKPALLEVMRMNRICRMVLATCLGSFILVIFYFQSML
HPVMRRNPFGVDICCRKGSRSPLQELYNPIQERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGAS

--------------------------------------------------------------

>16692_16692_2_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000303694_TXNRD1_chr12_104732917_ENST00000378070_length(amino acids)=261AA_BP=211
MERNEVAFGEKGEGPSDSHSGQRSGSGGGTTITARTPAARPATRQRRPPAGSEEAAERRGGGAGARSQRVHASQHFQTNSGTFHTPARAG
GSESGREATPILPLSLAQLCPAPPGLRSARRGPCSCAPGALPGHPGPRSQDKAMKPALLEVMRMNRICRMVLATCLGSFILVIFYFQSML

--------------------------------------------------------------

>16692_16692_3_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000303694_TXNRD1_chr12_104732917_ENST00000388854_length(amino acids)=276AA_BP=211
MERNEVAFGEKGEGPSDSHSGQRSGSGGGTTITARTPAARPATRQRRPPAGSEEAAERRGGGAGARSQRVHASQHFQTNSGTFHTPARAG
GSESGREATPILPLSLAQLCPAPPGLRSARRGPCSCAPGALPGHPGPRSQDKAMKPALLEVMRMNRICRMVLATCLGSFILVIFYFQSML
HPVMRRNPFGVDICCRKGSRSPLQELYNPIQERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGAS

--------------------------------------------------------------

>16692_16692_4_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000303694_TXNRD1_chr12_104732917_ENST00000397736_length(amino acids)=276AA_BP=211
MERNEVAFGEKGEGPSDSHSGQRSGSGGGTTITARTPAARPATRQRRPPAGSEEAAERRGGGAGARSQRVHASQHFQTNSGTFHTPARAG
GSESGREATPILPLSLAQLCPAPPGLRSARRGPCSCAPGALPGHPGPRSQDKAMKPALLEVMRMNRICRMVLATCLGSFILVIFYFQSML
HPVMRRNPFGVDICCRKGSRSPLQELYNPIQERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGAS

--------------------------------------------------------------

>16692_16692_5_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000303694_TXNRD1_chr12_104732917_ENST00000427956_length(amino acids)=276AA_BP=211
MERNEVAFGEKGEGPSDSHSGQRSGSGGGTTITARTPAARPATRQRRPPAGSEEAAERRGGGAGARSQRVHASQHFQTNSGTFHTPARAG
GSESGREATPILPLSLAQLCPAPPGLRSARRGPCSCAPGALPGHPGPRSQDKAMKPALLEVMRMNRICRMVLATCLGSFILVIFYFQSML
HPVMRRNPFGVDICCRKGSRSPLQELYNPIQERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGAS

--------------------------------------------------------------

>16692_16692_6_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000303694_TXNRD1_chr12_104732917_ENST00000429002_length(amino acids)=276AA_BP=211
MERNEVAFGEKGEGPSDSHSGQRSGSGGGTTITARTPAARPATRQRRPPAGSEEAAERRGGGAGARSQRVHASQHFQTNSGTFHTPARAG
GSESGREATPILPLSLAQLCPAPPGLRSARRGPCSCAPGALPGHPGPRSQDKAMKPALLEVMRMNRICRMVLATCLGSFILVIFYFQSML
HPVMRRNPFGVDICCRKGSRSPLQELYNPIQERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGAS

--------------------------------------------------------------

>16692_16692_7_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000303694_TXNRD1_chr12_104732917_ENST00000503506_length(amino acids)=276AA_BP=211
MERNEVAFGEKGEGPSDSHSGQRSGSGGGTTITARTPAARPATRQRRPPAGSEEAAERRGGGAGARSQRVHASQHFQTNSGTFHTPARAG
GSESGREATPILPLSLAQLCPAPPGLRSARRGPCSCAPGALPGHPGPRSQDKAMKPALLEVMRMNRICRMVLATCLGSFILVIFYFQSML
HPVMRRNPFGVDICCRKGSRSPLQELYNPIQERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGAS

--------------------------------------------------------------

>16692_16692_8_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000303694_TXNRD1_chr12_104732917_ENST00000524698_length(amino acids)=293AA_BP=1
MQSWQQHPHWGLTSAASLEDACPRALGHRQCCEYLCTDRVDSNCAVQLLFGQSTFERSCKALCNFSSIWTQYVKAHNTFLDWVVEFLQGA
SGPLPAADVHTKGIPPHDWVQHTLEIEDDQDKGSQASGQHHPADSVHPHHFQQRWLHGFVLAAGTGVSGKRARGAGAGTPPRGPEPGRRG
AELSKAQREDRSRFAAALGAPSPGRGVEGAGVGLEVLRCVDPLAARSCSSSSPLRRLLRSRRRPPLPGRGPGGWGASGDGGAAAAAAALA

--------------------------------------------------------------

>16692_16692_9_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000303694_TXNRD1_chr12_104732917_ENST00000525566_length(amino acids)=276AA_BP=211
MERNEVAFGEKGEGPSDSHSGQRSGSGGGTTITARTPAARPATRQRRPPAGSEEAAERRGGGAGARSQRVHASQHFQTNSGTFHTPARAG
GSESGREATPILPLSLAQLCPAPPGLRSARRGPCSCAPGALPGHPGPRSQDKAMKPALLEVMRMNRICRMVLATCLGSFILVIFYFQSML
HPVMRRNPFGVDICCRKGSRSPLQELYNPIQERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGAS

--------------------------------------------------------------

>16692_16692_10_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000303694_TXNRD1_chr12_104732917_ENST00000526390_length(amino acids)=276AA_BP=211
MERNEVAFGEKGEGPSDSHSGQRSGSGGGTTITARTPAARPATRQRRPPAGSEEAAERRGGGAGARSQRVHASQHFQTNSGTFHTPARAG
GSESGREATPILPLSLAQLCPAPPGLRSARRGPCSCAPGALPGHPGPRSQDKAMKPALLEVMRMNRICRMVLATCLGSFILVIFYFQSML
HPVMRRNPFGVDICCRKGSRSPLQELYNPIQERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGAS

--------------------------------------------------------------

>16692_16692_11_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000303694_TXNRD1_chr12_104732917_ENST00000526691_length(amino acids)=276AA_BP=211
MERNEVAFGEKGEGPSDSHSGQRSGSGGGTTITARTPAARPATRQRRPPAGSEEAAERRGGGAGARSQRVHASQHFQTNSGTFHTPARAG
GSESGREATPILPLSLAQLCPAPPGLRSARRGPCSCAPGALPGHPGPRSQDKAMKPALLEVMRMNRICRMVLATCLGSFILVIFYFQSML
HPVMRRNPFGVDICCRKGSRSPLQELYNPIQERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGAS

--------------------------------------------------------------

>16692_16692_12_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000303694_TXNRD1_chr12_104732917_ENST00000526950_length(amino acids)=276AA_BP=211
MERNEVAFGEKGEGPSDSHSGQRSGSGGGTTITARTPAARPATRQRRPPAGSEEAAERRGGGAGARSQRVHASQHFQTNSGTFHTPARAG
GSESGREATPILPLSLAQLCPAPPGLRSARRGPCSCAPGALPGHPGPRSQDKAMKPALLEVMRMNRICRMVLATCLGSFILVIFYFQSML
HPVMRRNPFGVDICCRKGSRSPLQELYNPIQERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGAS

--------------------------------------------------------------

>16692_16692_13_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000303694_TXNRD1_chr12_104732917_ENST00000529546_length(amino acids)=276AA_BP=211
MERNEVAFGEKGEGPSDSHSGQRSGSGGGTTITARTPAARPATRQRRPPAGSEEAAERRGGGAGARSQRVHASQHFQTNSGTFHTPARAG
GSESGREATPILPLSLAQLCPAPPGLRSARRGPCSCAPGALPGHPGPRSQDKAMKPALLEVMRMNRICRMVLATCLGSFILVIFYFQSML
HPVMRRNPFGVDICCRKGSRSPLQELYNPIQERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGAS

--------------------------------------------------------------

>16692_16692_14_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000303694_TXNRD1_chr12_104732917_ENST00000540716_length(amino acids)=293AA_BP=1
MQSWQQHPHWGLTSAASLEDACPRALGHRQCCEYLCTDRVDSNCAVQLLFGQSTFERSCKALCNFSSIWTQYVKAHNTFLDWVVEFLQGA
SGPLPAADVHTKGIPPHDWVQHTLEIEDDQDKGSQASGQHHPADSVHPHHFQQRWLHGFVLAAGTGVSGKRARGAGAGTPPRGPEPGRRG
AELSKAQREDRSRFAAALGAPSPGRGVEGAGVGLEVLRCVDPLAARSCSSSSPLRRLLRSRRRPPLPGRGPGGWGASGDGGAAAAAAALA

--------------------------------------------------------------

>16692_16692_15_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000303694_TXNRD1_chr12_104732917_ENST00000542918_length(amino acids)=293AA_BP=1
MQSWQQHPHWGLTSAASLEDACPRALGHRQCCEYLCTDRVDSNCAVQLLFGQSTFERSCKALCNFSSIWTQYVKAHNTFLDWVVEFLQGA
SGPLPAADVHTKGIPPHDWVQHTLEIEDDQDKGSQASGQHHPADSVHPHHFQQRWLHGFVLAAGTGVSGKRARGAGAGTPPRGPEPGRRG
AELSKAQREDRSRFAAALGAPSPGRGVEGAGVGLEVLRCVDPLAARSCSSSSPLRRLLRSRRRPPLPGRGPGGWGASGDGGAAAAAAALA

--------------------------------------------------------------

>16692_16692_16_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000303694_TXNRD1_chr12_104742130_ENST00000540716_length(amino acids)=248AA_BP=1
MQSWQQHPHWGLTSAASLEDACPRALGHRQCCEYLDWVVEFLQGASGPLPAADVHTKGIPPHDWVQHTLEIEDDQDKGSQASGQHHPADS
VHPHHFQQRWLHGFVLAAGTGVSGKRARGAGAGTPPRGPEPGRRGAELSKAQREDRSRFAAALGAPSPGRGVEGAGVGLEVLRCVDPLAA

--------------------------------------------------------------

>16692_16692_17_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000303694_TXNRD1_chr12_104742131_ENST00000540716_length(amino acids)=248AA_BP=1
MQSWQQHPHWGLTSAASLEDACPRALGHRQCCEYLDWVVEFLQGASGPLPAADVHTKGIPPHDWVQHTLEIEDDQDKGSQASGQHHPADS
VHPHHFQQRWLHGFVLAAGTGVSGKRARGAGAGTPPRGPEPGRRGAELSKAQREDRSRFAAALGAPSPGRGVEGAGVGLEVLRCVDPLAA

--------------------------------------------------------------

>16692_16692_18_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000546689_TXNRD1_chr12_104732917_ENST00000354940_length(amino acids)=180AA_BP=
MLTECLKLTLEIEDDQDKGSQASGQHHPADSVHPHHFQQRWLHGFVLAAGTGVSGKRARGAGAGTPPRGPEPGRRGAELSKAQREDRSRF
AAALGAPSPGRGVEGAGVGLEVLRCVDPLAARSCSSSSPLRRLLRSRRRPPLPGRGPGGWGASGDGGAAAAAAALAAVAVRRALSLLSKG

--------------------------------------------------------------

>16692_16692_19_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000546689_TXNRD1_chr12_104732917_ENST00000378070_length(amino acids)=118AA_BP=
MQSWQQHPHWGLTSAASLEDACPRALGHRQCCEYLWSQLLRRLRQEHRLSLKGQGCSELRSHHCTPAWVTGTLSQINEKNSAQTGWIPIV

--------------------------------------------------------------

>16692_16692_20_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000546689_TXNRD1_chr12_104732917_ENST00000388854_length(amino acids)=180AA_BP=
MLTECLKLTLEIEDDQDKGSQASGQHHPADSVHPHHFQQRWLHGFVLAAGTGVSGKRARGAGAGTPPRGPEPGRRGAELSKAQREDRSRF
AAALGAPSPGRGVEGAGVGLEVLRCVDPLAARSCSSSSPLRRLLRSRRRPPLPGRGPGGWGASGDGGAAAAAAALAAVAVRRALSLLSKG

--------------------------------------------------------------

>16692_16692_21_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000546689_TXNRD1_chr12_104732917_ENST00000397736_length(amino acids)=180AA_BP=
MLTECLKLTLEIEDDQDKGSQASGQHHPADSVHPHHFQQRWLHGFVLAAGTGVSGKRARGAGAGTPPRGPEPGRRGAELSKAQREDRSRF
AAALGAPSPGRGVEGAGVGLEVLRCVDPLAARSCSSSSPLRRLLRSRRRPPLPGRGPGGWGASGDGGAAAAAAALAAVAVRRALSLLSKG

--------------------------------------------------------------

>16692_16692_22_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000546689_TXNRD1_chr12_104732917_ENST00000427956_length(amino acids)=180AA_BP=
MLTECLKLTLEIEDDQDKGSQASGQHHPADSVHPHHFQQRWLHGFVLAAGTGVSGKRARGAGAGTPPRGPEPGRRGAELSKAQREDRSRF
AAALGAPSPGRGVEGAGVGLEVLRCVDPLAARSCSSSSPLRRLLRSRRRPPLPGRGPGGWGASGDGGAAAAAAALAAVAVRRALSLLSKG

--------------------------------------------------------------

>16692_16692_23_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000546689_TXNRD1_chr12_104732917_ENST00000429002_length(amino acids)=180AA_BP=
MLTECLKLTLEIEDDQDKGSQASGQHHPADSVHPHHFQQRWLHGFVLAAGTGVSGKRARGAGAGTPPRGPEPGRRGAELSKAQREDRSRF
AAALGAPSPGRGVEGAGVGLEVLRCVDPLAARSCSSSSPLRRLLRSRRRPPLPGRGPGGWGASGDGGAAAAAAALAAVAVRRALSLLSKG

--------------------------------------------------------------

>16692_16692_24_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000546689_TXNRD1_chr12_104732917_ENST00000503506_length(amino acids)=180AA_BP=
MLTECLKLTLEIEDDQDKGSQASGQHHPADSVHPHHFQQRWLHGFVLAAGTGVSGKRARGAGAGTPPRGPEPGRRGAELSKAQREDRSRF
AAALGAPSPGRGVEGAGVGLEVLRCVDPLAARSCSSSSPLRRLLRSRRRPPLPGRGPGGWGASGDGGAAAAAAALAAVAVRRALSLLSKG

--------------------------------------------------------------

>16692_16692_25_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000546689_TXNRD1_chr12_104732917_ENST00000524698_length(amino acids)=150AA_BP=29
MWSLGDLKLPFTAWHFTFSGCFLRHPFSRTCCGLSRTGSKCWRSYTRLCSCAQMWTDQKAAGQHNWNPPCLCRGIHNIVCDQALWGKHPP

--------------------------------------------------------------

>16692_16692_26_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000546689_TXNRD1_chr12_104732917_ENST00000525566_length(amino acids)=180AA_BP=
MLTECLKLTLEIEDDQDKGSQASGQHHPADSVHPHHFQQRWLHGFVLAAGTGVSGKRARGAGAGTPPRGPEPGRRGAELSKAQREDRSRF
AAALGAPSPGRGVEGAGVGLEVLRCVDPLAARSCSSSSPLRRLLRSRRRPPLPGRGPGGWGASGDGGAAAAAAALAAVAVRRALSLLSKG

--------------------------------------------------------------

>16692_16692_27_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000546689_TXNRD1_chr12_104732917_ENST00000526390_length(amino acids)=180AA_BP=
MLTECLKLTLEIEDDQDKGSQASGQHHPADSVHPHHFQQRWLHGFVLAAGTGVSGKRARGAGAGTPPRGPEPGRRGAELSKAQREDRSRF
AAALGAPSPGRGVEGAGVGLEVLRCVDPLAARSCSSSSPLRRLLRSRRRPPLPGRGPGGWGASGDGGAAAAAAALAAVAVRRALSLLSKG

--------------------------------------------------------------

>16692_16692_28_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000546689_TXNRD1_chr12_104732917_ENST00000526691_length(amino acids)=180AA_BP=
MLTECLKLTLEIEDDQDKGSQASGQHHPADSVHPHHFQQRWLHGFVLAAGTGVSGKRARGAGAGTPPRGPEPGRRGAELSKAQREDRSRF
AAALGAPSPGRGVEGAGVGLEVLRCVDPLAARSCSSSSPLRRLLRSRRRPPLPGRGPGGWGASGDGGAAAAAAALAAVAVRRALSLLSKG

--------------------------------------------------------------

>16692_16692_29_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000546689_TXNRD1_chr12_104732917_ENST00000526950_length(amino acids)=180AA_BP=
MLTECLKLTLEIEDDQDKGSQASGQHHPADSVHPHHFQQRWLHGFVLAAGTGVSGKRARGAGAGTPPRGPEPGRRGAELSKAQREDRSRF
AAALGAPSPGRGVEGAGVGLEVLRCVDPLAARSCSSSSPLRRLLRSRRRPPLPGRGPGGWGASGDGGAAAAAAALAAVAVRRALSLLSKG

--------------------------------------------------------------

>16692_16692_30_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000546689_TXNRD1_chr12_104732917_ENST00000529546_length(amino acids)=180AA_BP=
MLTECLKLTLEIEDDQDKGSQASGQHHPADSVHPHHFQQRWLHGFVLAAGTGVSGKRARGAGAGTPPRGPEPGRRGAELSKAQREDRSRF
AAALGAPSPGRGVEGAGVGLEVLRCVDPLAARSCSSSSPLRRLLRSRRRPPLPGRGPGGWGASGDGGAAAAAAALAAVAVRRALSLLSKG

--------------------------------------------------------------

>16692_16692_31_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000546689_TXNRD1_chr12_104732917_ENST00000540716_length(amino acids)=180AA_BP=
MLTECLKLTLEIEDDQDKGSQASGQHHPADSVHPHHFQQRWLHGFVLAAGTGVSGKRARGAGAGTPPRGPEPGRRGAELSKAQREDRSRF
AAALGAPSPGRGVEGAGVGLEVLRCVDPLAARSCSSSSPLRRLLRSRRRPPLPGRGPGGWGASGDGGAAAAAAALAAVAVRRALSLLSKG

--------------------------------------------------------------

>16692_16692_32_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000546689_TXNRD1_chr12_104732917_ENST00000542918_length(amino acids)=150AA_BP=29
MWSLGDLKLPFTAWHFTFSGCFLRHPFSRTCCGLSRTGSKCWRSYTRLCSCAQMWTDQKAAGQHNWNPPCLCRGIHNIVCDQALWGKHPP

--------------------------------------------------------------

>16692_16692_33_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000546689_TXNRD1_chr12_104742130_ENST00000540716_length(amino acids)=180AA_BP=
MLTECLKLTLEIEDDQDKGSQASGQHHPADSVHPHHFQQRWLHGFVLAAGTGVSGKRARGAGAGTPPRGPEPGRRGAELSKAQREDRSRF
AAALGAPSPGRGVEGAGVGLEVLRCVDPLAARSCSSSSPLRRLLRSRRRPPLPGRGPGGWGASGDGGAAAAAAALAAVAVRRALSLLSKG

--------------------------------------------------------------

>16692_16692_34_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000546689_TXNRD1_chr12_104742131_ENST00000540716_length(amino acids)=180AA_BP=
MLTECLKLTLEIEDDQDKGSQASGQHHPADSVHPHHFQQRWLHGFVLAAGTGVSGKRARGAGAGTPPRGPEPGRRGAELSKAQREDRSRF
AAALGAPSPGRGVEGAGVGLEVLRCVDPLAARSCSSSSPLRRLLRSRRRPPLPGRGPGGWGASGDGGAAAAAAALAAVAVRRALSLLSKG

--------------------------------------------------------------

>16692_16692_35_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000547956_TXNRD1_chr12_104732917_ENST00000354940_length(amino acids)=197AA_BP=
MERNEVAFGEKGEGPSDSHSGQRSGSGGGTTITARTPAARPATRQRRPPAGSEEAAERRGGGAGARSQRVHASQHFQTNSGTFHTPARAG
GSESGREATPILPLSLAQLCPAPPGLRSARRGPCSCAPGALPGHPGPRSQDKAMKPALLEVMRMNRICRMVLATCLGSFILVIFYFQSML

--------------------------------------------------------------

>16692_16692_36_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000547956_TXNRD1_chr12_104732917_ENST00000378070_length(amino acids)=197AA_BP=
MERNEVAFGEKGEGPSDSHSGQRSGSGGGTTITARTPAARPATRQRRPPAGSEEAAERRGGGAGARSQRVHASQHFQTNSGTFHTPARAG
GSESGREATPILPLSLAQLCPAPPGLRSARRGPCSCAPGALPGHPGPRSQDKAMKPALLEVMRMNRICRMVLATCLGSFILVIFYFQSML

--------------------------------------------------------------

>16692_16692_37_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000547956_TXNRD1_chr12_104732917_ENST00000388854_length(amino acids)=197AA_BP=
MERNEVAFGEKGEGPSDSHSGQRSGSGGGTTITARTPAARPATRQRRPPAGSEEAAERRGGGAGARSQRVHASQHFQTNSGTFHTPARAG
GSESGREATPILPLSLAQLCPAPPGLRSARRGPCSCAPGALPGHPGPRSQDKAMKPALLEVMRMNRICRMVLATCLGSFILVIFYFQSML

--------------------------------------------------------------

>16692_16692_38_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000547956_TXNRD1_chr12_104732917_ENST00000397736_length(amino acids)=197AA_BP=
MERNEVAFGEKGEGPSDSHSGQRSGSGGGTTITARTPAARPATRQRRPPAGSEEAAERRGGGAGARSQRVHASQHFQTNSGTFHTPARAG
GSESGREATPILPLSLAQLCPAPPGLRSARRGPCSCAPGALPGHPGPRSQDKAMKPALLEVMRMNRICRMVLATCLGSFILVIFYFQSML

--------------------------------------------------------------

>16692_16692_39_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000547956_TXNRD1_chr12_104732917_ENST00000427956_length(amino acids)=197AA_BP=
MERNEVAFGEKGEGPSDSHSGQRSGSGGGTTITARTPAARPATRQRRPPAGSEEAAERRGGGAGARSQRVHASQHFQTNSGTFHTPARAG
GSESGREATPILPLSLAQLCPAPPGLRSARRGPCSCAPGALPGHPGPRSQDKAMKPALLEVMRMNRICRMVLATCLGSFILVIFYFQSML

--------------------------------------------------------------

>16692_16692_40_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000547956_TXNRD1_chr12_104732917_ENST00000429002_length(amino acids)=197AA_BP=
MERNEVAFGEKGEGPSDSHSGQRSGSGGGTTITARTPAARPATRQRRPPAGSEEAAERRGGGAGARSQRVHASQHFQTNSGTFHTPARAG
GSESGREATPILPLSLAQLCPAPPGLRSARRGPCSCAPGALPGHPGPRSQDKAMKPALLEVMRMNRICRMVLATCLGSFILVIFYFQSML

--------------------------------------------------------------

>16692_16692_41_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000547956_TXNRD1_chr12_104732917_ENST00000503506_length(amino acids)=197AA_BP=
MERNEVAFGEKGEGPSDSHSGQRSGSGGGTTITARTPAARPATRQRRPPAGSEEAAERRGGGAGARSQRVHASQHFQTNSGTFHTPARAG
GSESGREATPILPLSLAQLCPAPPGLRSARRGPCSCAPGALPGHPGPRSQDKAMKPALLEVMRMNRICRMVLATCLGSFILVIFYFQSML

--------------------------------------------------------------

>16692_16692_42_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000547956_TXNRD1_chr12_104732917_ENST00000524698_length(amino acids)=197AA_BP=
MERNEVAFGEKGEGPSDSHSGQRSGSGGGTTITARTPAARPATRQRRPPAGSEEAAERRGGGAGARSQRVHASQHFQTNSGTFHTPARAG
GSESGREATPILPLSLAQLCPAPPGLRSARRGPCSCAPGALPGHPGPRSQDKAMKPALLEVMRMNRICRMVLATCLGSFILVIFYFQSML

--------------------------------------------------------------

>16692_16692_43_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000547956_TXNRD1_chr12_104732917_ENST00000525566_length(amino acids)=197AA_BP=
MERNEVAFGEKGEGPSDSHSGQRSGSGGGTTITARTPAARPATRQRRPPAGSEEAAERRGGGAGARSQRVHASQHFQTNSGTFHTPARAG
GSESGREATPILPLSLAQLCPAPPGLRSARRGPCSCAPGALPGHPGPRSQDKAMKPALLEVMRMNRICRMVLATCLGSFILVIFYFQSML

--------------------------------------------------------------

>16692_16692_44_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000547956_TXNRD1_chr12_104732917_ENST00000526390_length(amino acids)=197AA_BP=
MERNEVAFGEKGEGPSDSHSGQRSGSGGGTTITARTPAARPATRQRRPPAGSEEAAERRGGGAGARSQRVHASQHFQTNSGTFHTPARAG
GSESGREATPILPLSLAQLCPAPPGLRSARRGPCSCAPGALPGHPGPRSQDKAMKPALLEVMRMNRICRMVLATCLGSFILVIFYFQSML

--------------------------------------------------------------

>16692_16692_45_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000547956_TXNRD1_chr12_104732917_ENST00000526691_length(amino acids)=197AA_BP=
MERNEVAFGEKGEGPSDSHSGQRSGSGGGTTITARTPAARPATRQRRPPAGSEEAAERRGGGAGARSQRVHASQHFQTNSGTFHTPARAG
GSESGREATPILPLSLAQLCPAPPGLRSARRGPCSCAPGALPGHPGPRSQDKAMKPALLEVMRMNRICRMVLATCLGSFILVIFYFQSML

--------------------------------------------------------------

>16692_16692_46_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000547956_TXNRD1_chr12_104732917_ENST00000526950_length(amino acids)=197AA_BP=
MERNEVAFGEKGEGPSDSHSGQRSGSGGGTTITARTPAARPATRQRRPPAGSEEAAERRGGGAGARSQRVHASQHFQTNSGTFHTPARAG
GSESGREATPILPLSLAQLCPAPPGLRSARRGPCSCAPGALPGHPGPRSQDKAMKPALLEVMRMNRICRMVLATCLGSFILVIFYFQSML

--------------------------------------------------------------

>16692_16692_47_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000547956_TXNRD1_chr12_104732917_ENST00000529546_length(amino acids)=197AA_BP=
MERNEVAFGEKGEGPSDSHSGQRSGSGGGTTITARTPAARPATRQRRPPAGSEEAAERRGGGAGARSQRVHASQHFQTNSGTFHTPARAG
GSESGREATPILPLSLAQLCPAPPGLRSARRGPCSCAPGALPGHPGPRSQDKAMKPALLEVMRMNRICRMVLATCLGSFILVIFYFQSML

--------------------------------------------------------------

>16692_16692_48_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000547956_TXNRD1_chr12_104732917_ENST00000540716_length(amino acids)=197AA_BP=
MERNEVAFGEKGEGPSDSHSGQRSGSGGGTTITARTPAARPATRQRRPPAGSEEAAERRGGGAGARSQRVHASQHFQTNSGTFHTPARAG
GSESGREATPILPLSLAQLCPAPPGLRSARRGPCSCAPGALPGHPGPRSQDKAMKPALLEVMRMNRICRMVLATCLGSFILVIFYFQSML

--------------------------------------------------------------

>16692_16692_49_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000547956_TXNRD1_chr12_104732917_ENST00000542918_length(amino acids)=197AA_BP=
MERNEVAFGEKGEGPSDSHSGQRSGSGGGTTITARTPAARPATRQRRPPAGSEEAAERRGGGAGARSQRVHASQHFQTNSGTFHTPARAG
GSESGREATPILPLSLAQLCPAPPGLRSARRGPCSCAPGALPGHPGPRSQDKAMKPALLEVMRMNRICRMVLATCLGSFILVIFYFQSML

--------------------------------------------------------------

>16692_16692_50_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000547956_TXNRD1_chr12_104742130_ENST00000540716_length(amino acids)=197AA_BP=
MERNEVAFGEKGEGPSDSHSGQRSGSGGGTTITARTPAARPATRQRRPPAGSEEAAERRGGGAGARSQRVHASQHFQTNSGTFHTPARAG
GSESGREATPILPLSLAQLCPAPPGLRSARRGPCSCAPGALPGHPGPRSQDKAMKPALLEVMRMNRICRMVLATCLGSFILVIFYFQSML

--------------------------------------------------------------

>16692_16692_51_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000547956_TXNRD1_chr12_104742131_ENST00000540716_length(amino acids)=197AA_BP=
MERNEVAFGEKGEGPSDSHSGQRSGSGGGTTITARTPAARPATRQRRPPAGSEEAAERRGGGAGARSQRVHASQHFQTNSGTFHTPARAG
GSESGREATPILPLSLAQLCPAPPGLRSARRGPCSCAPGALPGHPGPRSQDKAMKPALLEVMRMNRICRMVLATCLGSFILVIFYFQSML

--------------------------------------------------------------

>16692_16692_52_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000549260_TXNRD1_chr12_104732917_ENST00000354940_length(amino acids)=271AA_BP=206
MERNEVAFGEKGEGPSDSHSGQRSGSGGGTTITARTPAARPATRQRRPPAGSEEAAERRGGGAGARSQRVHASQHFQTNSGTFHTPARAG
GSESGREATPILPLSLAQLCPAPPGLRSARRGPCSCAPGALPGHPGPRSQDKAMKPALLEVMRMNRICRMVLATCLGSFILVIFYFQIMR
RNPFGVDICCRKGSRSPLQELYNPIQERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGASILQAG

--------------------------------------------------------------

>16692_16692_53_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000549260_TXNRD1_chr12_104732917_ENST00000378070_length(amino acids)=256AA_BP=206
MERNEVAFGEKGEGPSDSHSGQRSGSGGGTTITARTPAARPATRQRRPPAGSEEAAERRGGGAGARSQRVHASQHFQTNSGTFHTPARAG
GSESGREATPILPLSLAQLCPAPPGLRSARRGPCSCAPGALPGHPGPRSQDKAMKPALLEVMRMNRICRMVLATCLGSFILVIFYFQIMR

--------------------------------------------------------------

>16692_16692_54_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000549260_TXNRD1_chr12_104732917_ENST00000388854_length(amino acids)=271AA_BP=206
MERNEVAFGEKGEGPSDSHSGQRSGSGGGTTITARTPAARPATRQRRPPAGSEEAAERRGGGAGARSQRVHASQHFQTNSGTFHTPARAG
GSESGREATPILPLSLAQLCPAPPGLRSARRGPCSCAPGALPGHPGPRSQDKAMKPALLEVMRMNRICRMVLATCLGSFILVIFYFQIMR
RNPFGVDICCRKGSRSPLQELYNPIQERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGASILQAG

--------------------------------------------------------------

>16692_16692_55_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000549260_TXNRD1_chr12_104732917_ENST00000397736_length(amino acids)=271AA_BP=206
MERNEVAFGEKGEGPSDSHSGQRSGSGGGTTITARTPAARPATRQRRPPAGSEEAAERRGGGAGARSQRVHASQHFQTNSGTFHTPARAG
GSESGREATPILPLSLAQLCPAPPGLRSARRGPCSCAPGALPGHPGPRSQDKAMKPALLEVMRMNRICRMVLATCLGSFILVIFYFQIMR
RNPFGVDICCRKGSRSPLQELYNPIQERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGASILQAG

--------------------------------------------------------------

>16692_16692_56_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000549260_TXNRD1_chr12_104732917_ENST00000427956_length(amino acids)=271AA_BP=206
MERNEVAFGEKGEGPSDSHSGQRSGSGGGTTITARTPAARPATRQRRPPAGSEEAAERRGGGAGARSQRVHASQHFQTNSGTFHTPARAG
GSESGREATPILPLSLAQLCPAPPGLRSARRGPCSCAPGALPGHPGPRSQDKAMKPALLEVMRMNRICRMVLATCLGSFILVIFYFQIMR
RNPFGVDICCRKGSRSPLQELYNPIQERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGASILQAG

--------------------------------------------------------------

>16692_16692_57_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000549260_TXNRD1_chr12_104732917_ENST00000429002_length(amino acids)=271AA_BP=206
MERNEVAFGEKGEGPSDSHSGQRSGSGGGTTITARTPAARPATRQRRPPAGSEEAAERRGGGAGARSQRVHASQHFQTNSGTFHTPARAG
GSESGREATPILPLSLAQLCPAPPGLRSARRGPCSCAPGALPGHPGPRSQDKAMKPALLEVMRMNRICRMVLATCLGSFILVIFYFQIMR
RNPFGVDICCRKGSRSPLQELYNPIQERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGASILQAG

--------------------------------------------------------------

>16692_16692_58_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000549260_TXNRD1_chr12_104732917_ENST00000503506_length(amino acids)=271AA_BP=206
MERNEVAFGEKGEGPSDSHSGQRSGSGGGTTITARTPAARPATRQRRPPAGSEEAAERRGGGAGARSQRVHASQHFQTNSGTFHTPARAG
GSESGREATPILPLSLAQLCPAPPGLRSARRGPCSCAPGALPGHPGPRSQDKAMKPALLEVMRMNRICRMVLATCLGSFILVIFYFQIMR
RNPFGVDICCRKGSRSPLQELYNPIQERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGASILQAG

--------------------------------------------------------------

>16692_16692_59_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000549260_TXNRD1_chr12_104732917_ENST00000524698_length(amino acids)=289AA_BP=1
MQSWQQHPHWGLTSAASLEDACPRALGHRQCCEYLCTDRVDSNCAVQLLFGQSTFERSCKALCNFSSIWTQYVKAHNTFLDWVVEFLQGA
SGPLPAADVHTKGIPPHDLEIEDDQDKGSQASGQHHPADSVHPHHFQQRWLHGFVLAAGTGVSGKRARGAGAGTPPRGPEPGRRGAELSK
AQREDRSRFAAALGAPSPGRGVEGAGVGLEVLRCVDPLAARSCSSSSPLRRLLRSRRRPPLPGRGPGGWGASGDGGAAAAAAALAAVAVR

--------------------------------------------------------------

>16692_16692_60_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000549260_TXNRD1_chr12_104732917_ENST00000525566_length(amino acids)=271AA_BP=206
MERNEVAFGEKGEGPSDSHSGQRSGSGGGTTITARTPAARPATRQRRPPAGSEEAAERRGGGAGARSQRVHASQHFQTNSGTFHTPARAG
GSESGREATPILPLSLAQLCPAPPGLRSARRGPCSCAPGALPGHPGPRSQDKAMKPALLEVMRMNRICRMVLATCLGSFILVIFYFQIMR
RNPFGVDICCRKGSRSPLQELYNPIQERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGASILQAG

--------------------------------------------------------------

>16692_16692_61_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000549260_TXNRD1_chr12_104732917_ENST00000526390_length(amino acids)=271AA_BP=206
MERNEVAFGEKGEGPSDSHSGQRSGSGGGTTITARTPAARPATRQRRPPAGSEEAAERRGGGAGARSQRVHASQHFQTNSGTFHTPARAG
GSESGREATPILPLSLAQLCPAPPGLRSARRGPCSCAPGALPGHPGPRSQDKAMKPALLEVMRMNRICRMVLATCLGSFILVIFYFQIMR
RNPFGVDICCRKGSRSPLQELYNPIQERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGASILQAG

--------------------------------------------------------------

>16692_16692_62_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000549260_TXNRD1_chr12_104732917_ENST00000526691_length(amino acids)=271AA_BP=206
MERNEVAFGEKGEGPSDSHSGQRSGSGGGTTITARTPAARPATRQRRPPAGSEEAAERRGGGAGARSQRVHASQHFQTNSGTFHTPARAG
GSESGREATPILPLSLAQLCPAPPGLRSARRGPCSCAPGALPGHPGPRSQDKAMKPALLEVMRMNRICRMVLATCLGSFILVIFYFQIMR
RNPFGVDICCRKGSRSPLQELYNPIQERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGASILQAG

--------------------------------------------------------------

>16692_16692_63_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000549260_TXNRD1_chr12_104732917_ENST00000526950_length(amino acids)=271AA_BP=206
MERNEVAFGEKGEGPSDSHSGQRSGSGGGTTITARTPAARPATRQRRPPAGSEEAAERRGGGAGARSQRVHASQHFQTNSGTFHTPARAG
GSESGREATPILPLSLAQLCPAPPGLRSARRGPCSCAPGALPGHPGPRSQDKAMKPALLEVMRMNRICRMVLATCLGSFILVIFYFQIMR
RNPFGVDICCRKGSRSPLQELYNPIQERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGASILQAG

--------------------------------------------------------------

>16692_16692_64_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000549260_TXNRD1_chr12_104732917_ENST00000529546_length(amino acids)=271AA_BP=206
MERNEVAFGEKGEGPSDSHSGQRSGSGGGTTITARTPAARPATRQRRPPAGSEEAAERRGGGAGARSQRVHASQHFQTNSGTFHTPARAG
GSESGREATPILPLSLAQLCPAPPGLRSARRGPCSCAPGALPGHPGPRSQDKAMKPALLEVMRMNRICRMVLATCLGSFILVIFYFQIMR
RNPFGVDICCRKGSRSPLQELYNPIQERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGASILQAG

--------------------------------------------------------------

>16692_16692_65_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000549260_TXNRD1_chr12_104732917_ENST00000540716_length(amino acids)=289AA_BP=1
MQSWQQHPHWGLTSAASLEDACPRALGHRQCCEYLCTDRVDSNCAVQLLFGQSTFERSCKALCNFSSIWTQYVKAHNTFLDWVVEFLQGA
SGPLPAADVHTKGIPPHDLEIEDDQDKGSQASGQHHPADSVHPHHFQQRWLHGFVLAAGTGVSGKRARGAGAGTPPRGPEPGRRGAELSK
AQREDRSRFAAALGAPSPGRGVEGAGVGLEVLRCVDPLAARSCSSSSPLRRLLRSRRRPPLPGRGPGGWGASGDGGAAAAAAALAAVAVR

--------------------------------------------------------------

>16692_16692_66_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000549260_TXNRD1_chr12_104732917_ENST00000542918_length(amino acids)=289AA_BP=1
MQSWQQHPHWGLTSAASLEDACPRALGHRQCCEYLCTDRVDSNCAVQLLFGQSTFERSCKALCNFSSIWTQYVKAHNTFLDWVVEFLQGA
SGPLPAADVHTKGIPPHDLEIEDDQDKGSQASGQHHPADSVHPHHFQQRWLHGFVLAAGTGVSGKRARGAGAGTPPRGPEPGRRGAELSK
AQREDRSRFAAALGAPSPGRGVEGAGVGLEVLRCVDPLAARSCSSSSPLRRLLRSRRRPPLPGRGPGGWGASGDGGAAAAAAALAAVAVR

--------------------------------------------------------------

>16692_16692_67_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000549260_TXNRD1_chr12_104742130_ENST00000540716_length(amino acids)=244AA_BP=1
MQSWQQHPHWGLTSAASLEDACPRALGHRQCCEYLDWVVEFLQGASGPLPAADVHTKGIPPHDLEIEDDQDKGSQASGQHHPADSVHPHH
FQQRWLHGFVLAAGTGVSGKRARGAGAGTPPRGPEPGRRGAELSKAQREDRSRFAAALGAPSPGRGVEGAGVGLEVLRCVDPLAARSCSS

--------------------------------------------------------------

>16692_16692_68_CHST11-TXNRD1_CHST11_chr12_104995769_ENST00000549260_TXNRD1_chr12_104742131_ENST00000540716_length(amino acids)=244AA_BP=1
MQSWQQHPHWGLTSAASLEDACPRALGHRQCCEYLDWVVEFLQGASGPLPAADVHTKGIPPHDLEIEDDQDKGSQASGQHHPADSVHPHH
FQQRWLHGFVLAAGTGVSGKRARGAGAGTPPRGPEPGRRGAELSKAQREDRSRFAAALGAPSPGRGVEGAGVGLEVLRCVDPLAARSCSS

--------------------------------------------------------------

Top

Fusion Protein Functional Features


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:104995769/chr12:104732917)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CHST11

Q9NPF2

.
FUNCTION: Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Can also sulfate Gal residues in desulfated dermatan sulfate. Preferentially sulfates in GlcA->GalNAc unit than in IdoA->GalNAc unit. Does not form 4, 6-di-O-sulfated GalNAc when chondroitin sulfate C is used as an acceptor.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

* Minus value of BPloci means that the break pointn is located before the CDS.
- Retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCHST11chr12:104995769chr12:104732917ENST00000303694+231_1668.0353.0Topological domainCytoplasmic
HgeneCHST11chr12:104995769chr12:104732917ENST00000549260+231_1663.0348.0Topological domainCytoplasmic
HgeneCHST11chr12:104995769chr12:104742130ENST00000303694+231_1668.0353.0Topological domainCytoplasmic
HgeneCHST11chr12:104995769chr12:104742130ENST00000549260+231_1663.0348.0Topological domainCytoplasmic
HgeneCHST11chr12:104995769chr12:104742131ENST00000303694+231_1668.0353.0Topological domainCytoplasmic
HgeneCHST11chr12:104995769chr12:104742131ENST00000549260+231_1663.0348.0Topological domainCytoplasmic
HgeneCHST11chr12:104995769chr12:104732917ENST00000303694+2317_3768.0353.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
HgeneCHST11chr12:104995769chr12:104732917ENST00000549260+2317_3763.0348.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
HgeneCHST11chr12:104995769chr12:104742130ENST00000303694+2317_3768.0353.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
HgeneCHST11chr12:104995769chr12:104742130ENST00000549260+2317_3763.0348.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
HgeneCHST11chr12:104995769chr12:104742131ENST00000303694+2317_3768.0353.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
HgeneCHST11chr12:104995769chr12:104742131ENST00000549260+2317_3763.0348.0TransmembraneHelical%3B Signal-anchor for type II membrane protein

- Not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCHST11chr12:104995769chr12:104732917ENST00000303694+23124_13068.0353.0Nucleotide bindingPAPS
HgeneCHST11chr12:104995769chr12:104732917ENST00000303694+23186_19468.0353.0Nucleotide bindingPAPS
HgeneCHST11chr12:104995769chr12:104732917ENST00000549260+23124_13063.0348.0Nucleotide bindingPAPS
HgeneCHST11chr12:104995769chr12:104732917ENST00000549260+23186_19463.0348.0Nucleotide bindingPAPS
HgeneCHST11chr12:104995769chr12:104742130ENST00000303694+23124_13068.0353.0Nucleotide bindingPAPS
HgeneCHST11chr12:104995769chr12:104742130ENST00000303694+23186_19468.0353.0Nucleotide bindingPAPS
HgeneCHST11chr12:104995769chr12:104742130ENST00000549260+23124_13063.0348.0Nucleotide bindingPAPS
HgeneCHST11chr12:104995769chr12:104742130ENST00000549260+23186_19463.0348.0Nucleotide bindingPAPS
HgeneCHST11chr12:104995769chr12:104742131ENST00000303694+23124_13068.0353.0Nucleotide bindingPAPS
HgeneCHST11chr12:104995769chr12:104742131ENST00000303694+23186_19468.0353.0Nucleotide bindingPAPS
HgeneCHST11chr12:104995769chr12:104742131ENST00000549260+23124_13063.0348.0Nucleotide bindingPAPS
HgeneCHST11chr12:104995769chr12:104742131ENST00000549260+23186_19463.0348.0Nucleotide bindingPAPS
HgeneCHST11chr12:104995769chr12:104732917ENST00000303694+2338_35268.0353.0Topological domainLumenal
HgeneCHST11chr12:104995769chr12:104732917ENST00000549260+2338_35263.0348.0Topological domainLumenal
HgeneCHST11chr12:104995769chr12:104742130ENST00000303694+2338_35268.0353.0Topological domainLumenal
HgeneCHST11chr12:104995769chr12:104742130ENST00000549260+2338_35263.0348.0Topological domainLumenal
HgeneCHST11chr12:104995769chr12:104742131ENST00000303694+2338_35268.0353.0Topological domainLumenal
HgeneCHST11chr12:104995769chr12:104742131ENST00000549260+2338_35263.0348.0Topological domainLumenal
TgeneTXNRD1chr12:104995769chr12:104732917ENST00000388854121556_156484.0550.0DomainGlutaredoxin
TgeneTXNRD1chr12:104995769chr12:104732917ENST00000503506121556_156432.0500.0DomainGlutaredoxin
TgeneTXNRD1chr12:104995769chr12:104732917ENST00000524698121556_156432.0500.0DomainGlutaredoxin
TgeneTXNRD1chr12:104995769chr12:104732917ENST00000525566141756_156582.0650.0DomainGlutaredoxin
TgeneTXNRD1chr12:104995769chr12:104732917ENST00000526390141756_156476.0544.0DomainGlutaredoxin
TgeneTXNRD1chr12:104995769chr12:104732917ENST00000526691121556_156484.0552.0DomainGlutaredoxin
TgeneTXNRD1chr12:104995769chr12:104742130ENST00000388854131556_156529.0550.0DomainGlutaredoxin
TgeneTXNRD1chr12:104995769chr12:104742130ENST00000503506131556_156477.0500.0DomainGlutaredoxin
TgeneTXNRD1chr12:104995769chr12:104742130ENST00000524698131556_156477.0500.0DomainGlutaredoxin
TgeneTXNRD1chr12:104995769chr12:104742130ENST00000525566151756_156627.0650.0DomainGlutaredoxin
TgeneTXNRD1chr12:104995769chr12:104742130ENST00000526390151756_156521.0544.0DomainGlutaredoxin
TgeneTXNRD1chr12:104995769chr12:104742130ENST00000526691131556_156529.0552.0DomainGlutaredoxin
TgeneTXNRD1chr12:104995769chr12:104742131ENST00000388854131556_156529.0550.0DomainGlutaredoxin
TgeneTXNRD1chr12:104995769chr12:104742131ENST00000503506131556_156477.0500.0DomainGlutaredoxin
TgeneTXNRD1chr12:104995769chr12:104742131ENST00000524698131556_156477.0500.0DomainGlutaredoxin
TgeneTXNRD1chr12:104995769chr12:104742131ENST00000525566151756_156627.0650.0DomainGlutaredoxin
TgeneTXNRD1chr12:104995769chr12:104742131ENST00000526390151756_156521.0544.0DomainGlutaredoxin
TgeneTXNRD1chr12:104995769chr12:104742131ENST00000526691131556_156529.0552.0DomainGlutaredoxin
TgeneTXNRD1chr12:104995769chr12:104732917ENST000003888541215192_209484.0550.0Nucleotide bindingFAD
TgeneTXNRD1chr12:104995769chr12:104732917ENST000005035061215192_209432.0500.0Nucleotide bindingFAD
TgeneTXNRD1chr12:104995769chr12:104732917ENST000005246981215192_209432.0500.0Nucleotide bindingFAD
TgeneTXNRD1chr12:104995769chr12:104732917ENST000005255661417192_209582.0650.0Nucleotide bindingFAD
TgeneTXNRD1chr12:104995769chr12:104732917ENST000005263901417192_209476.0544.0Nucleotide bindingFAD
TgeneTXNRD1chr12:104995769chr12:104732917ENST000005266911215192_209484.0552.0Nucleotide bindingFAD
TgeneTXNRD1chr12:104995769chr12:104742130ENST000003888541315192_209529.0550.0Nucleotide bindingFAD
TgeneTXNRD1chr12:104995769chr12:104742130ENST000005035061315192_209477.0500.0Nucleotide bindingFAD
TgeneTXNRD1chr12:104995769chr12:104742130ENST000005246981315192_209477.0500.0Nucleotide bindingFAD
TgeneTXNRD1chr12:104995769chr12:104742130ENST000005255661517192_209627.0650.0Nucleotide bindingFAD
TgeneTXNRD1chr12:104995769chr12:104742130ENST000005263901517192_209521.0544.0Nucleotide bindingFAD
TgeneTXNRD1chr12:104995769chr12:104742130ENST000005266911315192_209529.0552.0Nucleotide bindingFAD
TgeneTXNRD1chr12:104995769chr12:104742131ENST000003888541315192_209529.0550.0Nucleotide bindingFAD
TgeneTXNRD1chr12:104995769chr12:104742131ENST000005035061315192_209477.0500.0Nucleotide bindingFAD
TgeneTXNRD1chr12:104995769chr12:104742131ENST000005246981315192_209477.0500.0Nucleotide bindingFAD
TgeneTXNRD1chr12:104995769chr12:104742131ENST000005255661517192_209627.0650.0Nucleotide bindingFAD
TgeneTXNRD1chr12:104995769chr12:104742131ENST000005263901517192_209521.0544.0Nucleotide bindingFAD
TgeneTXNRD1chr12:104995769chr12:104742131ENST000005266911315192_209529.0552.0Nucleotide bindingFAD


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Fusion Protein Structures

check button PDB and CIF files of the predicted fusion proteins
* Here we show the 3D structure of the fusion proteins using Mol*. AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Model confidence is shown from the pLDDT values per residue. pLDDT corresponds to the model’s prediction of its score on the local Distance Difference Test. It is a measure of local accuracy (from AlphfaFold website). To color code individual residues, we transformed individual PDB files into CIF format.
Fusion protein PDB link (fusion AA seq ID in FusionPDB)HgeneHchrHbpHstrandTgeneTchrTbpTstrandAA seqLen(AA seq)
PDB file >>>520_CHST11_104995769_TXNRD1_104732917_ranked_0.pdbCHST11104995769104995769ENST00000540716TXNRD1chr12104732917+
MQSWQQHPHWGLTSAASLEDACPRALGHRQCCEYLCTDRVDSNCAVQLLFGQSTFERSCKALCNFSSIWTQYVKAHNTFLDWVVEFLQGA
SGPLPAADVHTKGIPPHDWVQHTLEIEDDQDKGSQASGQHHPADSVHPHHFQQRWLHGFVLAAGTGVSGKRARGAGAGTPPRGPEPGRRG
AELSKAQREDRSRFAAALGAPSPGRGVEGAGVGLEVLRCVDPLAARSCSSSSPLRRLLRSRRRPPLPGRGPGGWGASGDGGAAAAAAALA
293


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pLDDT score distribution

check button pLDDT score distribution of the predicted wild-type structures of two partner proteins from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.
CHST11_pLDDT.png
all structure
all structure

all structure

check button pLDDT score distribution of the predicted fusion protein structures from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.
all structure


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Ramachandran Plot of Fusion Protein Structure


check button Ramachandran plot of the torsional angles - phi (φ)and psi (ψ) - of the residues (amino acids) contained in this fusion protein peptide.
Fusion AA seq ID in FusionPDB and their Ramachandran plots

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Fusion Protein-Protein Interaction


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)
GenePPI interactors


check button Protein-protein interactors based on sequence similarity (STRING)
GeneSTRING network
CHST11
TXNRD1


check button - Retained interactions in fusion protein (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost interactions due to fusion (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs to CHST11-TXNRD1


check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

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Related Diseases to CHST11-TXNRD1


check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource