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Center for Computational Systems Medicine level2
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Fusion Gene Summary

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Fusion Gene Sample Information

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Fusion ORF Analysis

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Fusion Amino Acid Sequences

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Fusion Protein Functional Features

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Fusion Protein Structure

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pLDDT scores

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Ramachandran Plot of Fusion Protein Structure

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Fusion Protein-Protein Interaction

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Related drugs with this fusion protein

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Related disease with this fusion protein

Fusion Protein:DMBT1-ARMS2

Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: DMBT1-ARMS2
FusionPDB ID: 23206
FusionGDB2.0 ID: 23206
HgeneTgene
Gene symbol

DMBT1

ARMS2

Gene ID

1755

387715

Gene namedeleted in malignant brain tumors 1age-related maculopathy susceptibility 2
SynonymsGP340|SAG|SALSA|muclinARMD8
Cytomap

10q26.13

10q26.13

Type of geneprotein-codingprotein-coding
Descriptiondeleted in malignant brain tumors 1 proteinglycoprotein 340hensinsalivary agglutininsalivary scavenger and agglutininsurfactant pulmonary-associated D-binding proteinvomeroglandinage-related maculopathy susceptibility protein 2
Modification date2020031320200315
UniProtAcc

Q9UGM3

.
Ensembl transtripts involved in fusion geneENST idsENST00000330163, ENST00000338354, 
ENST00000344338, ENST00000368909, 
ENST00000368955, ENST00000368956, 
ENST00000359586, 		ENST00000528446, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score3 X 4 X 2=244 X 2 X 4=32
# samples 46
** MAII scorelog2(4/24*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(6/32*10)=0.906890595608518
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context (manual curation of fusion genes in FusionPDB)

PubMed: DMBT1 [Title/Abstract] AND ARMS2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)DMBT1(124380896)-ARMS2(124216423), # samples:3
Anticipated loss of major functional domain due to fusion event.DMBT1-ARMS2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
DMBT1-ARMS2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
DMBT1-ARMS2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
DMBT1-ARMS2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across DMBT1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ARMS2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


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Fusion Gene Sample Information

check buttonFusion gene information from FusionGDB2.0.
check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4ESCATCGA-Q9-A6FW-01ADMBT1chr10

124380896

-ARMS2chr10

124216423

+
ChimerDB4ESCATCGA-Q9-A6FW-01ADMBT1chr10

124380896

+ARMS2chr10

124216423

+
ChimerDB4ESCATCGA-Q9-A6FWDMBT1chr10

124339417

+ARMS2chr10

124216422

+
ChimerDB4ESCATCGA-Q9-A6FWDMBT1chr10

124380896

+ARMS2chr10

124216422

+
ChimerDB4ESCATCGA-Q9-A6FWDMBT1chr10

124380896

+ARMS2chr10

124216423

+


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Fusion ORF Analysis


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000344338DMBT1chr10124380896+ENST00000528446ARMS2chr10124216423+5743529710653821758
ENST00000368955DMBT1chr10124380896+ENST00000528446ARMS2chr10124216423+5743529710653821758
ENST00000330163DMBT1chr10124380896+ENST00000528446ARMS2chr10124216423+3889344310635281140
ENST00000338354DMBT1chr10124380896+ENST00000528446ARMS2chr10124216423+5773532710654121768
ENST00000368956DMBT1chr10124380896+ENST00000528446ARMS2chr10124216423+3889344310635281140
ENST00000368909DMBT1chr10124380896+ENST00000528446ARMS2chr10124216423+5773532710654121768
ENST00000344338DMBT1chr10124380896+ENST00000528446ARMS2chr10124216422+5743529710653821758
ENST00000368955DMBT1chr10124380896+ENST00000528446ARMS2chr10124216422+5743529710653821758
ENST00000330163DMBT1chr10124380896+ENST00000528446ARMS2chr10124216422+3889344310635281140
ENST00000338354DMBT1chr10124380896+ENST00000528446ARMS2chr10124216422+5773532710654121768
ENST00000368956DMBT1chr10124380896+ENST00000528446ARMS2chr10124216422+3889344310635281140
ENST00000368909DMBT1chr10124380896+ENST00000528446ARMS2chr10124216422+5773532710654121768
ENST00000344338DMBT1chr10124339417+ENST00000528446ARMS2chr10124216422+155511091061194362
ENST00000368955DMBT1chr10124339417+ENST00000528446ARMS2chr10124216422+155511091061194362
ENST00000330163DMBT1chr10124339417+ENST00000528446ARMS2chr10124216422+155511091061194362
ENST00000338354DMBT1chr10124339417+ENST00000528446ARMS2chr10124216422+155511091061194362
ENST00000368956DMBT1chr10124339417+ENST00000528446ARMS2chr10124216422+155511091061194362
ENST00000368909DMBT1chr10124339417+ENST00000528446ARMS2chr10124216422+155511091061194362

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000344338ENST00000528446DMBT1chr10124380896+ARMS2chr10124216423+0.0045931590.99540687
ENST00000368955ENST00000528446DMBT1chr10124380896+ARMS2chr10124216423+0.0045931590.99540687
ENST00000330163ENST00000528446DMBT1chr10124380896+ARMS2chr10124216423+0.0046384020.9953616
ENST00000338354ENST00000528446DMBT1chr10124380896+ARMS2chr10124216423+0.0046648280.99533516
ENST00000368956ENST00000528446DMBT1chr10124380896+ARMS2chr10124216423+0.0046384020.9953616
ENST00000368909ENST00000528446DMBT1chr10124380896+ARMS2chr10124216423+0.0046648280.99533516
ENST00000344338ENST00000528446DMBT1chr10124380896+ARMS2chr10124216422+0.0045931590.99540687
ENST00000368955ENST00000528446DMBT1chr10124380896+ARMS2chr10124216422+0.0045931590.99540687
ENST00000330163ENST00000528446DMBT1chr10124380896+ARMS2chr10124216422+0.0046384020.9953616
ENST00000338354ENST00000528446DMBT1chr10124380896+ARMS2chr10124216422+0.0046648280.99533516
ENST00000368956ENST00000528446DMBT1chr10124380896+ARMS2chr10124216422+0.0046384020.9953616
ENST00000368909ENST00000528446DMBT1chr10124380896+ARMS2chr10124216422+0.0046648280.99533516
ENST00000344338ENST00000528446DMBT1chr10124339417+ARMS2chr10124216422+0.0837552250.9162448
ENST00000368955ENST00000528446DMBT1chr10124339417+ARMS2chr10124216422+0.0837552250.9162448
ENST00000330163ENST00000528446DMBT1chr10124339417+ARMS2chr10124216422+0.0837552250.9162448
ENST00000338354ENST00000528446DMBT1chr10124339417+ARMS2chr10124216422+0.0837552250.9162448
ENST00000368956ENST00000528446DMBT1chr10124339417+ARMS2chr10124216422+0.0837552250.9162448
ENST00000368909ENST00000528446DMBT1chr10124339417+ARMS2chr10124216422+0.0837552250.9162448

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Fusion Amino Acid Sequences


check button For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>23206_23206_1_DMBT1-ARMS2_DMBT1_chr10_124339417_ENST00000330163_ARMS2_chr10_124216422_ENST00000528446_length(amino acids)=362AA_BP=87
MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDPTVAEGSPFPSESTLESTVAEGSPISLESTLESTVAEGSLIPSESTLES
TVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS
CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANV
VCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSVYHPHCSKVILPKHISLKANWSFSSA

--------------------------------------------------------------

>23206_23206_2_DMBT1-ARMS2_DMBT1_chr10_124339417_ENST00000338354_ARMS2_chr10_124216422_ENST00000528446_length(amino acids)=362AA_BP=87
MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDPTVAEGSPFPSESTLESTVAEGSPISLESTLESTVAEGSLIPSESTLES
TVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS
CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANV
VCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSVYHPHCSKVILPKHISLKANWSFSSA

--------------------------------------------------------------

>23206_23206_3_DMBT1-ARMS2_DMBT1_chr10_124339417_ENST00000344338_ARMS2_chr10_124216422_ENST00000528446_length(amino acids)=362AA_BP=87
MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDPTVAEGSPFPSESTLESTVAEGSPISLESTLESTVAEGSLIPSESTLES
TVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS
CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANV
VCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSVYHPHCSKVILPKHISLKANWSFSSA

--------------------------------------------------------------

>23206_23206_4_DMBT1-ARMS2_DMBT1_chr10_124339417_ENST00000368909_ARMS2_chr10_124216422_ENST00000528446_length(amino acids)=362AA_BP=87
MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDPTVAEGSPFPSESTLESTVAEGSPISLESTLESTVAEGSLIPSESTLES
TVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS
CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANV
VCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSVYHPHCSKVILPKHISLKANWSFSSA

--------------------------------------------------------------

>23206_23206_5_DMBT1-ARMS2_DMBT1_chr10_124339417_ENST00000368955_ARMS2_chr10_124216422_ENST00000528446_length(amino acids)=362AA_BP=87
MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDPTVAEGSPFPSESTLESTVAEGSPISLESTLESTVAEGSLIPSESTLES
TVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS
CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANV
VCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSVYHPHCSKVILPKHISLKANWSFSSA

--------------------------------------------------------------

>23206_23206_6_DMBT1-ARMS2_DMBT1_chr10_124339417_ENST00000368956_ARMS2_chr10_124216422_ENST00000528446_length(amino acids)=362AA_BP=87
MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDPTVAEGSPFPSESTLESTVAEGSPISLESTLESTVAEGSLIPSESTLES
TVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS
CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANV
VCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSVYHPHCSKVILPKHISLKANWSFSSA

--------------------------------------------------------------

>23206_23206_7_DMBT1-ARMS2_DMBT1_chr10_124380896_ENST00000330163_ARMS2_chr10_124216422_ENST00000528446_length(amino acids)=1140AA_BP=87
MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDPTVAEGSPFPSESTLESTVAEGSPISLESTLESTVAEGSLIPSESTLES
TVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS
CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANV
VCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESS
LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSH
NCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWA
MSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGD
RCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGV
ICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQG
SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQG
SWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPR
PDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVR

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>23206_23206_8_DMBT1-ARMS2_DMBT1_chr10_124380896_ENST00000330163_ARMS2_chr10_124216423_ENST00000528446_length(amino acids)=1140AA_BP=87
MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDPTVAEGSPFPSESTLESTVAEGSPISLESTLESTVAEGSLIPSESTLES
TVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS
CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANV
VCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESS
LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSH
NCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWA
MSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGD
RCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGV
ICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQG
SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQG
SWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPR
PDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVR

--------------------------------------------------------------

>23206_23206_9_DMBT1-ARMS2_DMBT1_chr10_124380896_ENST00000338354_ARMS2_chr10_124216422_ENST00000528446_length(amino acids)=1768AA_BP=87
MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDPTVAEGSPFPSESTLESTVAEGSPISLESTLESTVAEGSLIPSESTLES
TVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS
CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANV
VCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESS
LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSH
NCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWA
MLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDS
WDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTLSTITL
PPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLW
SCPHNGWLSHNCGHHEDAGVICSVSQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVC
RQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESS
LALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSH
NCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMS
APGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRC
QGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVIC
SASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSG
PIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSW
GTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPD
TWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCS

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>23206_23206_10_DMBT1-ARMS2_DMBT1_chr10_124380896_ENST00000338354_ARMS2_chr10_124216423_ENST00000528446_length(amino acids)=1768AA_BP=87
MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDPTVAEGSPFPSESTLESTVAEGSPISLESTLESTVAEGSLIPSESTLES
TVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS
CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANV
VCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESS
LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSH
NCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWA
MLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDS
WDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTLSTITL
PPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLW
SCPHNGWLSHNCGHHEDAGVICSVSQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVC
RQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESS
LALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSH
NCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMS
APGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRC
QGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVIC
SASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSG
PIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSW
GTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPD
TWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCS

--------------------------------------------------------------

>23206_23206_11_DMBT1-ARMS2_DMBT1_chr10_124380896_ENST00000344338_ARMS2_chr10_124216422_ENST00000528446_length(amino acids)=1758AA_BP=87
MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDPTVAEGSPFPSESTLESTVAEGSPISLESTLESTVAEGSLIPSESTLES
TVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS
CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANV
VCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESS
LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSH
NCQHSEDAGVICSDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFG
QGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVC
RQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTLSTITLPPSTVGSESS
LTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSH
NCGHHEDAGVICSVSQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATS
APGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGD
RCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGV
ICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQG
SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRG
SWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPS
PDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCS
GHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDT
NDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPAL
TVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCP

--------------------------------------------------------------

>23206_23206_12_DMBT1-ARMS2_DMBT1_chr10_124380896_ENST00000344338_ARMS2_chr10_124216423_ENST00000528446_length(amino acids)=1758AA_BP=87
MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDPTVAEGSPFPSESTLESTVAEGSPISLESTLESTVAEGSLIPSESTLES
TVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS
CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANV
VCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESS
LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSH
NCQHSEDAGVICSDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFG
QGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVC
RQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTLSTITLPPSTVGSESS
LTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSH
NCGHHEDAGVICSVSQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATS
APGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGD
RCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGV
ICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQG
SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRG
SWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPS
PDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCS
GHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDT
NDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPAL
TVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCP

--------------------------------------------------------------

>23206_23206_13_DMBT1-ARMS2_DMBT1_chr10_124380896_ENST00000368909_ARMS2_chr10_124216422_ENST00000528446_length(amino acids)=1768AA_BP=87
MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDPTVAEGSPFPSESTLESTVAEGSPISLESTLESTVAEGSLIPSESTLES
TVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS
CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANV
VCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESS
LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSH
NCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWA
MLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDS
WDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTLSTITL
PPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLW
SCPHNGWLSHNCGHHEDAGVICSVSQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVC
RQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESS
LALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSH
NCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMS
APGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRC
QGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVIC
SASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSG
PIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSW
GTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPD
TWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCS

--------------------------------------------------------------

>23206_23206_14_DMBT1-ARMS2_DMBT1_chr10_124380896_ENST00000368909_ARMS2_chr10_124216423_ENST00000528446_length(amino acids)=1768AA_BP=87
MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDPTVAEGSPFPSESTLESTVAEGSPISLESTLESTVAEGSLIPSESTLES
TVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS
CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANV
VCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESS
LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSH
NCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWA
MLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDS
WDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTLSTITL
PPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLW
SCPHNGWLSHNCGHHEDAGVICSVSQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVC
RQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESS
LALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSH
NCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMS
APGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRC
QGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVIC
SASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSG
PIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSW
GTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPD
TWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCS

--------------------------------------------------------------

>23206_23206_15_DMBT1-ARMS2_DMBT1_chr10_124380896_ENST00000368955_ARMS2_chr10_124216422_ENST00000528446_length(amino acids)=1758AA_BP=87
MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDPTVAEGSPFPSESTLESTVAEGSPISLESTLESTVAEGSLIPSESTLES
TVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS
CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANV
VCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESS
LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSH
NCQHSEDAGVICSDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFG
QGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVC
RQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTLSTITLPPSTVGSESS
LTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSH
NCGHHEDAGVICSVSQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATS
APGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGD
RCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGV
ICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQG
SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRG
SWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPS
PDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCS
GHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDT
NDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPAL
TVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCP

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>23206_23206_16_DMBT1-ARMS2_DMBT1_chr10_124380896_ENST00000368955_ARMS2_chr10_124216423_ENST00000528446_length(amino acids)=1758AA_BP=87
MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDPTVAEGSPFPSESTLESTVAEGSPISLESTLESTVAEGSLIPSESTLES
TVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS
CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANV
VCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESS
LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSH
NCQHSEDAGVICSDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFG
QGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVC
RQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTLSTITLPPSTVGSESS
LTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSH
NCGHHEDAGVICSVSQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATS
APGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGD
RCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGV
ICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQG
SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRG
SWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPS
PDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCS
GHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDT
NDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPAL
TVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCP

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>23206_23206_17_DMBT1-ARMS2_DMBT1_chr10_124380896_ENST00000368956_ARMS2_chr10_124216422_ENST00000528446_length(amino acids)=1140AA_BP=87
MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDPTVAEGSPFPSESTLESTVAEGSPISLESTLESTVAEGSLIPSESTLES
TVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS
CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANV
VCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESS
LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSH
NCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWA
MSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGD
RCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGV
ICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQG
SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQG
SWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPR
PDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVR

--------------------------------------------------------------

>23206_23206_18_DMBT1-ARMS2_DMBT1_chr10_124380896_ENST00000368956_ARMS2_chr10_124216423_ENST00000528446_length(amino acids)=1140AA_BP=87
MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDPTVAEGSPFPSESTLESTVAEGSPISLESTLESTVAEGSLIPSESTLES
TVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS
CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANV
VCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESS
LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSH
NCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWA
MSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGD
RCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGV
ICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQG
SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQG
SWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPR
PDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVR

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Fusion Protein Functional Features


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr10:124380896/chr10:124216423)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
DMBT1

Q9UGM3

.
FUNCTION: May be considered as a candidate tumor suppressor gene for brain, lung, esophageal, gastric, and colorectal cancers. May play roles in mucosal defense system, cellular immune defense and epithelial differentiation. May play a role as an opsonin receptor for SFTPD and SPAR in macrophage tissues throughout the body, including epithelial cells lining the gastrointestinal tract. May play a role in liver regeneration. May be an important factor in fate decision and differentiation of transit-amplifying ductular (oval) cells within the hepatic lineage. Required for terminal differentiation of columnar epithelial cells during early embryogenesis. May function as a binding protein in saliva for the regulation of taste sensation. Binds to HIV-1 envelope protein and has been shown to both inhibit and facilitate viral transmission. Displays a broad calcium-dependent binding spectrum against both Gram-positive and Gram-negative bacteria, suggesting a role in defense against bacterial pathogens. Binds to a range of poly-sulfated and poly-phosphorylated ligands which may explain its broad bacterial-binding specificity. Inhibits cytoinvasion of S.enterica. Associates with the actin cytoskeleton and is involved in its remodeling during regulated exocytosis. Interacts with pancreatic zymogens in a pH-dependent manner and may act as a Golgi cargo receptor in the regulated secretory pathway of the pancreatic acinar cell. {ECO:0000269|PubMed:10485905, ECO:0000269|PubMed:11007786, ECO:0000269|PubMed:11751412, ECO:0000269|PubMed:16796526, ECO:0000269|PubMed:17548659, ECO:0000269|PubMed:17709527, ECO:0000269|PubMed:19189310, ECO:0000269|PubMed:9288095}.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

* Minus value of BPloci means that the break pointn is located before the CDS.
- Retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneDMBT1chr10:124339417chr10:124216422ENST00000330163+1040102_202334.33333333333331786.0DomainSRCR 1
HgeneDMBT1chr10:124339417chr10:124216422ENST00000330163+1040234_334334.33333333333331786.0DomainSRCR 2
HgeneDMBT1chr10:124339417chr10:124216422ENST00000338354+1053102_202334.33333333333332414.0DomainSRCR 1
HgeneDMBT1chr10:124339417chr10:124216422ENST00000338354+1053234_334334.33333333333332414.0DomainSRCR 2
HgeneDMBT1chr10:124339417chr10:124216422ENST00000344338+1052102_202334.33333333333332404.0DomainSRCR 1
HgeneDMBT1chr10:124339417chr10:124216422ENST00000344338+1052234_334334.33333333333332404.0DomainSRCR 2
HgeneDMBT1chr10:124339417chr10:124216422ENST00000368909+1053102_202334.33333333333332414.0DomainSRCR 1
HgeneDMBT1chr10:124339417chr10:124216422ENST00000368909+1053234_334334.33333333333332414.0DomainSRCR 2
HgeneDMBT1chr10:124339417chr10:124216422ENST00000368955+1052102_202334.33333333333332404.0DomainSRCR 1
HgeneDMBT1chr10:124339417chr10:124216422ENST00000368955+1052234_334334.33333333333332404.0DomainSRCR 2
HgeneDMBT1chr10:124339417chr10:124216422ENST00000368956+1040102_202334.33333333333331786.0DomainSRCR 1
HgeneDMBT1chr10:124339417chr10:124216422ENST00000368956+1040234_334334.33333333333331786.0DomainSRCR 2
HgeneDMBT1chr10:124380896chr10:124216422ENST00000330163+2840102_2021112.33333333333331786.0DomainSRCR 1
HgeneDMBT1chr10:124380896chr10:124216422ENST00000330163+2840234_3341112.33333333333331786.0DomainSRCR 2
HgeneDMBT1chr10:124380896chr10:124216422ENST00000330163+2840363_4631112.33333333333331786.0DomainSRCR 3
HgeneDMBT1chr10:124380896chr10:124216422ENST00000330163+2840494_5941112.33333333333331786.0DomainSRCR 4
HgeneDMBT1chr10:124380896chr10:124216422ENST00000330163+2840602_7021112.33333333333331786.0DomainSRCR 5
HgeneDMBT1chr10:124380896chr10:124216422ENST00000330163+2840733_8331112.33333333333331786.0DomainSRCR 6
HgeneDMBT1chr10:124380896chr10:124216422ENST00000330163+2840862_9621112.33333333333331786.0DomainSRCR 7
HgeneDMBT1chr10:124380896chr10:124216422ENST00000330163+2840993_10931112.33333333333331786.0DomainSRCR 8
HgeneDMBT1chr10:124380896chr10:124216422ENST00000338354+4153102_2021740.33333333333332414.0DomainSRCR 1
HgeneDMBT1chr10:124380896chr10:124216422ENST00000338354+41531122_12221740.33333333333332414.0DomainSRCR 9
HgeneDMBT1chr10:124380896chr10:124216422ENST00000338354+41531251_13511740.33333333333332414.0DomainSRCR 10
HgeneDMBT1chr10:124380896chr10:124216422ENST00000338354+41531380_14801740.33333333333332414.0DomainSRCR 11
HgeneDMBT1chr10:124380896chr10:124216422ENST00000338354+41531509_16091740.33333333333332414.0DomainSRCR 12
HgeneDMBT1chr10:124380896chr10:124216422ENST00000338354+41531640_17401740.33333333333332414.0DomainSRCR 13
HgeneDMBT1chr10:124380896chr10:124216422ENST00000338354+4153234_3341740.33333333333332414.0DomainSRCR 2
HgeneDMBT1chr10:124380896chr10:124216422ENST00000338354+4153363_4631740.33333333333332414.0DomainSRCR 3
HgeneDMBT1chr10:124380896chr10:124216422ENST00000338354+4153494_5941740.33333333333332414.0DomainSRCR 4
HgeneDMBT1chr10:124380896chr10:124216422ENST00000338354+4153602_7021740.33333333333332414.0DomainSRCR 5
HgeneDMBT1chr10:124380896chr10:124216422ENST00000338354+4153733_8331740.33333333333332414.0DomainSRCR 6
HgeneDMBT1chr10:124380896chr10:124216422ENST00000338354+4153862_9621740.33333333333332414.0DomainSRCR 7
HgeneDMBT1chr10:124380896chr10:124216422ENST00000338354+4153993_10931740.33333333333332414.0DomainSRCR 8
HgeneDMBT1chr10:124380896chr10:124216422ENST00000344338+4052102_2021730.33333333333332404.0DomainSRCR 1
HgeneDMBT1chr10:124380896chr10:124216422ENST00000344338+40521122_12221730.33333333333332404.0DomainSRCR 9
HgeneDMBT1chr10:124380896chr10:124216422ENST00000344338+40521251_13511730.33333333333332404.0DomainSRCR 10
HgeneDMBT1chr10:124380896chr10:124216422ENST00000344338+40521380_14801730.33333333333332404.0DomainSRCR 11
HgeneDMBT1chr10:124380896chr10:124216422ENST00000344338+40521509_16091730.33333333333332404.0DomainSRCR 12
HgeneDMBT1chr10:124380896chr10:124216422ENST00000344338+4052234_3341730.33333333333332404.0DomainSRCR 2
HgeneDMBT1chr10:124380896chr10:124216422ENST00000344338+4052363_4631730.33333333333332404.0DomainSRCR 3
HgeneDMBT1chr10:124380896chr10:124216422ENST00000344338+4052494_5941730.33333333333332404.0DomainSRCR 4
HgeneDMBT1chr10:124380896chr10:124216422ENST00000344338+4052602_7021730.33333333333332404.0DomainSRCR 5
HgeneDMBT1chr10:124380896chr10:124216422ENST00000344338+4052733_8331730.33333333333332404.0DomainSRCR 6
HgeneDMBT1chr10:124380896chr10:124216422ENST00000344338+4052862_9621730.33333333333332404.0DomainSRCR 7
HgeneDMBT1chr10:124380896chr10:124216422ENST00000344338+4052993_10931730.33333333333332404.0DomainSRCR 8
HgeneDMBT1chr10:124380896chr10:124216422ENST00000368909+4153102_2021740.33333333333332414.0DomainSRCR 1
HgeneDMBT1chr10:124380896chr10:124216422ENST00000368909+41531122_12221740.33333333333332414.0DomainSRCR 9
HgeneDMBT1chr10:124380896chr10:124216422ENST00000368909+41531251_13511740.33333333333332414.0DomainSRCR 10
HgeneDMBT1chr10:124380896chr10:124216422ENST00000368909+41531380_14801740.33333333333332414.0DomainSRCR 11
HgeneDMBT1chr10:124380896chr10:124216422ENST00000368909+41531509_16091740.33333333333332414.0DomainSRCR 12
HgeneDMBT1chr10:124380896chr10:124216422ENST00000368909+41531640_17401740.33333333333332414.0DomainSRCR 13
HgeneDMBT1chr10:124380896chr10:124216422ENST00000368909+4153234_3341740.33333333333332414.0DomainSRCR 2
HgeneDMBT1chr10:124380896chr10:124216422ENST00000368909+4153363_4631740.33333333333332414.0DomainSRCR 3
HgeneDMBT1chr10:124380896chr10:124216422ENST00000368909+4153494_5941740.33333333333332414.0DomainSRCR 4
HgeneDMBT1chr10:124380896chr10:124216422ENST00000368909+4153602_7021740.33333333333332414.0DomainSRCR 5
HgeneDMBT1chr10:124380896chr10:124216422ENST00000368909+4153733_8331740.33333333333332414.0DomainSRCR 6
HgeneDMBT1chr10:124380896chr10:124216422ENST00000368909+4153862_9621740.33333333333332414.0DomainSRCR 7
HgeneDMBT1chr10:124380896chr10:124216422ENST00000368909+4153993_10931740.33333333333332414.0DomainSRCR 8
HgeneDMBT1chr10:124380896chr10:124216422ENST00000368955+4052102_2021730.33333333333332404.0DomainSRCR 1
HgeneDMBT1chr10:124380896chr10:124216422ENST00000368955+40521122_12221730.33333333333332404.0DomainSRCR 9
HgeneDMBT1chr10:124380896chr10:124216422ENST00000368955+40521251_13511730.33333333333332404.0DomainSRCR 10
HgeneDMBT1chr10:124380896chr10:124216422ENST00000368955+40521380_14801730.33333333333332404.0DomainSRCR 11
HgeneDMBT1chr10:124380896chr10:124216422ENST00000368955+40521509_16091730.33333333333332404.0DomainSRCR 12
HgeneDMBT1chr10:124380896chr10:124216422ENST00000368955+4052234_3341730.33333333333332404.0DomainSRCR 2
HgeneDMBT1chr10:124380896chr10:124216422ENST00000368955+4052363_4631730.33333333333332404.0DomainSRCR 3
HgeneDMBT1chr10:124380896chr10:124216422ENST00000368955+4052494_5941730.33333333333332404.0DomainSRCR 4
HgeneDMBT1chr10:124380896chr10:124216422ENST00000368955+4052602_7021730.33333333333332404.0DomainSRCR 5
HgeneDMBT1chr10:124380896chr10:124216422ENST00000368955+4052733_8331730.33333333333332404.0DomainSRCR 6
HgeneDMBT1chr10:124380896chr10:124216422ENST00000368955+4052862_9621730.33333333333332404.0DomainSRCR 7
HgeneDMBT1chr10:124380896chr10:124216422ENST00000368955+4052993_10931730.33333333333332404.0DomainSRCR 8
HgeneDMBT1chr10:124380896chr10:124216422ENST00000368956+2840102_2021112.33333333333331786.0DomainSRCR 1
HgeneDMBT1chr10:124380896chr10:124216422ENST00000368956+2840234_3341112.33333333333331786.0DomainSRCR 2
HgeneDMBT1chr10:124380896chr10:124216422ENST00000368956+2840363_4631112.33333333333331786.0DomainSRCR 3
HgeneDMBT1chr10:124380896chr10:124216422ENST00000368956+2840494_5941112.33333333333331786.0DomainSRCR 4
HgeneDMBT1chr10:124380896chr10:124216422ENST00000368956+2840602_7021112.33333333333331786.0DomainSRCR 5
HgeneDMBT1chr10:124380896chr10:124216422ENST00000368956+2840733_8331112.33333333333331786.0DomainSRCR 6
HgeneDMBT1chr10:124380896chr10:124216422ENST00000368956+2840862_9621112.33333333333331786.0DomainSRCR 7
HgeneDMBT1chr10:124380896chr10:124216422ENST00000368956+2840993_10931112.33333333333331786.0DomainSRCR 8
HgeneDMBT1chr10:124380896chr10:124216423ENST00000330163+2840102_2021112.33333333333331786.0DomainSRCR 1
HgeneDMBT1chr10:124380896chr10:124216423ENST00000330163+2840234_3341112.33333333333331786.0DomainSRCR 2
HgeneDMBT1chr10:124380896chr10:124216423ENST00000330163+2840363_4631112.33333333333331786.0DomainSRCR 3
HgeneDMBT1chr10:124380896chr10:124216423ENST00000330163+2840494_5941112.33333333333331786.0DomainSRCR 4
HgeneDMBT1chr10:124380896chr10:124216423ENST00000330163+2840602_7021112.33333333333331786.0DomainSRCR 5
HgeneDMBT1chr10:124380896chr10:124216423ENST00000330163+2840733_8331112.33333333333331786.0DomainSRCR 6
HgeneDMBT1chr10:124380896chr10:124216423ENST00000330163+2840862_9621112.33333333333331786.0DomainSRCR 7
HgeneDMBT1chr10:124380896chr10:124216423ENST00000330163+2840993_10931112.33333333333331786.0DomainSRCR 8
HgeneDMBT1chr10:124380896chr10:124216423ENST00000338354+4153102_2021740.33333333333332414.0DomainSRCR 1
HgeneDMBT1chr10:124380896chr10:124216423ENST00000338354+41531122_12221740.33333333333332414.0DomainSRCR 9
HgeneDMBT1chr10:124380896chr10:124216423ENST00000338354+41531251_13511740.33333333333332414.0DomainSRCR 10
HgeneDMBT1chr10:124380896chr10:124216423ENST00000338354+41531380_14801740.33333333333332414.0DomainSRCR 11
HgeneDMBT1chr10:124380896chr10:124216423ENST00000338354+41531509_16091740.33333333333332414.0DomainSRCR 12
HgeneDMBT1chr10:124380896chr10:124216423ENST00000338354+41531640_17401740.33333333333332414.0DomainSRCR 13
HgeneDMBT1chr10:124380896chr10:124216423ENST00000338354+4153234_3341740.33333333333332414.0DomainSRCR 2
HgeneDMBT1chr10:124380896chr10:124216423ENST00000338354+4153363_4631740.33333333333332414.0DomainSRCR 3
HgeneDMBT1chr10:124380896chr10:124216423ENST00000338354+4153494_5941740.33333333333332414.0DomainSRCR 4
HgeneDMBT1chr10:124380896chr10:124216423ENST00000338354+4153602_7021740.33333333333332414.0DomainSRCR 5
HgeneDMBT1chr10:124380896chr10:124216423ENST00000338354+4153733_8331740.33333333333332414.0DomainSRCR 6
HgeneDMBT1chr10:124380896chr10:124216423ENST00000338354+4153862_9621740.33333333333332414.0DomainSRCR 7
HgeneDMBT1chr10:124380896chr10:124216423ENST00000338354+4153993_10931740.33333333333332414.0DomainSRCR 8
HgeneDMBT1chr10:124380896chr10:124216423ENST00000344338+4052102_2021730.33333333333332404.0DomainSRCR 1
HgeneDMBT1chr10:124380896chr10:124216423ENST00000344338+40521122_12221730.33333333333332404.0DomainSRCR 9
HgeneDMBT1chr10:124380896chr10:124216423ENST00000344338+40521251_13511730.33333333333332404.0DomainSRCR 10
HgeneDMBT1chr10:124380896chr10:124216423ENST00000344338+40521380_14801730.33333333333332404.0DomainSRCR 11
HgeneDMBT1chr10:124380896chr10:124216423ENST00000344338+40521509_16091730.33333333333332404.0DomainSRCR 12
HgeneDMBT1chr10:124380896chr10:124216423ENST00000344338+4052234_3341730.33333333333332404.0DomainSRCR 2
HgeneDMBT1chr10:124380896chr10:124216423ENST00000344338+4052363_4631730.33333333333332404.0DomainSRCR 3
HgeneDMBT1chr10:124380896chr10:124216423ENST00000344338+4052494_5941730.33333333333332404.0DomainSRCR 4
HgeneDMBT1chr10:124380896chr10:124216423ENST00000344338+4052602_7021730.33333333333332404.0DomainSRCR 5
HgeneDMBT1chr10:124380896chr10:124216423ENST00000344338+4052733_8331730.33333333333332404.0DomainSRCR 6
HgeneDMBT1chr10:124380896chr10:124216423ENST00000344338+4052862_9621730.33333333333332404.0DomainSRCR 7
HgeneDMBT1chr10:124380896chr10:124216423ENST00000344338+4052993_10931730.33333333333332404.0DomainSRCR 8
HgeneDMBT1chr10:124380896chr10:124216423ENST00000368909+4153102_2021740.33333333333332414.0DomainSRCR 1
HgeneDMBT1chr10:124380896chr10:124216423ENST00000368909+41531122_12221740.33333333333332414.0DomainSRCR 9
HgeneDMBT1chr10:124380896chr10:124216423ENST00000368909+41531251_13511740.33333333333332414.0DomainSRCR 10
HgeneDMBT1chr10:124380896chr10:124216423ENST00000368909+41531380_14801740.33333333333332414.0DomainSRCR 11
HgeneDMBT1chr10:124380896chr10:124216423ENST00000368909+41531509_16091740.33333333333332414.0DomainSRCR 12
HgeneDMBT1chr10:124380896chr10:124216423ENST00000368909+41531640_17401740.33333333333332414.0DomainSRCR 13
HgeneDMBT1chr10:124380896chr10:124216423ENST00000368909+4153234_3341740.33333333333332414.0DomainSRCR 2
HgeneDMBT1chr10:124380896chr10:124216423ENST00000368909+4153363_4631740.33333333333332414.0DomainSRCR 3
HgeneDMBT1chr10:124380896chr10:124216423ENST00000368909+4153494_5941740.33333333333332414.0DomainSRCR 4
HgeneDMBT1chr10:124380896chr10:124216423ENST00000368909+4153602_7021740.33333333333332414.0DomainSRCR 5
HgeneDMBT1chr10:124380896chr10:124216423ENST00000368909+4153733_8331740.33333333333332414.0DomainSRCR 6
HgeneDMBT1chr10:124380896chr10:124216423ENST00000368909+4153862_9621740.33333333333332414.0DomainSRCR 7
HgeneDMBT1chr10:124380896chr10:124216423ENST00000368909+4153993_10931740.33333333333332414.0DomainSRCR 8
HgeneDMBT1chr10:124380896chr10:124216423ENST00000368955+4052102_2021730.33333333333332404.0DomainSRCR 1
HgeneDMBT1chr10:124380896chr10:124216423ENST00000368955+40521122_12221730.33333333333332404.0DomainSRCR 9
HgeneDMBT1chr10:124380896chr10:124216423ENST00000368955+40521251_13511730.33333333333332404.0DomainSRCR 10
HgeneDMBT1chr10:124380896chr10:124216423ENST00000368955+40521380_14801730.33333333333332404.0DomainSRCR 11
HgeneDMBT1chr10:124380896chr10:124216423ENST00000368955+40521509_16091730.33333333333332404.0DomainSRCR 12
HgeneDMBT1chr10:124380896chr10:124216423ENST00000368955+4052234_3341730.33333333333332404.0DomainSRCR 2
HgeneDMBT1chr10:124380896chr10:124216423ENST00000368955+4052363_4631730.33333333333332404.0DomainSRCR 3
HgeneDMBT1chr10:124380896chr10:124216423ENST00000368955+4052494_5941730.33333333333332404.0DomainSRCR 4
HgeneDMBT1chr10:124380896chr10:124216423ENST00000368955+4052602_7021730.33333333333332404.0DomainSRCR 5
HgeneDMBT1chr10:124380896chr10:124216423ENST00000368955+4052733_8331730.33333333333332404.0DomainSRCR 6
HgeneDMBT1chr10:124380896chr10:124216423ENST00000368955+4052862_9621730.33333333333332404.0DomainSRCR 7
HgeneDMBT1chr10:124380896chr10:124216423ENST00000368955+4052993_10931730.33333333333332404.0DomainSRCR 8
HgeneDMBT1chr10:124380896chr10:124216423ENST00000368956+2840102_2021112.33333333333331786.0DomainSRCR 1
HgeneDMBT1chr10:124380896chr10:124216423ENST00000368956+2840234_3341112.33333333333331786.0DomainSRCR 2
HgeneDMBT1chr10:124380896chr10:124216423ENST00000368956+2840363_4631112.33333333333331786.0DomainSRCR 3
HgeneDMBT1chr10:124380896chr10:124216423ENST00000368956+2840494_5941112.33333333333331786.0DomainSRCR 4
HgeneDMBT1chr10:124380896chr10:124216423ENST00000368956+2840602_7021112.33333333333331786.0DomainSRCR 5
HgeneDMBT1chr10:124380896chr10:124216423ENST00000368956+2840733_8331112.33333333333331786.0DomainSRCR 6
HgeneDMBT1chr10:124380896chr10:124216423ENST00000368956+2840862_9621112.33333333333331786.0DomainSRCR 7
HgeneDMBT1chr10:124380896chr10:124216423ENST00000368956+2840993_10931112.33333333333331786.0DomainSRCR 8

- Not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneDMBT1chr10:124339417chr10:124216422ENST00000330163+10401755_1759334.33333333333331786.0Compositional biasNote=Poly-Thr
HgeneDMBT1chr10:124339417chr10:124216422ENST00000338354+10531755_1759334.33333333333332414.0Compositional biasNote=Poly-Thr
HgeneDMBT1chr10:124339417chr10:124216422ENST00000344338+10521755_1759334.33333333333332404.0Compositional biasNote=Poly-Thr
HgeneDMBT1chr10:124339417chr10:124216422ENST00000368909+10531755_1759334.33333333333332414.0Compositional biasNote=Poly-Thr
HgeneDMBT1chr10:124339417chr10:124216422ENST00000368955+10521755_1759334.33333333333332404.0Compositional biasNote=Poly-Thr
HgeneDMBT1chr10:124339417chr10:124216422ENST00000368956+10401755_1759334.33333333333331786.0Compositional biasNote=Poly-Thr
HgeneDMBT1chr10:124380896chr10:124216422ENST00000330163+28401755_17591112.33333333333331786.0Compositional biasNote=Poly-Thr
HgeneDMBT1chr10:124380896chr10:124216422ENST00000338354+41531755_17591740.33333333333332414.0Compositional biasNote=Poly-Thr
HgeneDMBT1chr10:124380896chr10:124216422ENST00000344338+40521755_17591730.33333333333332404.0Compositional biasNote=Poly-Thr
HgeneDMBT1chr10:124380896chr10:124216422ENST00000368909+41531755_17591740.33333333333332414.0Compositional biasNote=Poly-Thr
HgeneDMBT1chr10:124380896chr10:124216422ENST00000368955+40521755_17591730.33333333333332404.0Compositional biasNote=Poly-Thr
HgeneDMBT1chr10:124380896chr10:124216422ENST00000368956+28401755_17591112.33333333333331786.0Compositional biasNote=Poly-Thr
HgeneDMBT1chr10:124380896chr10:124216423ENST00000330163+28401755_17591112.33333333333331786.0Compositional biasNote=Poly-Thr
HgeneDMBT1chr10:124380896chr10:124216423ENST00000338354+41531755_17591740.33333333333332414.0Compositional biasNote=Poly-Thr
HgeneDMBT1chr10:124380896chr10:124216423ENST00000344338+40521755_17591730.33333333333332404.0Compositional biasNote=Poly-Thr
HgeneDMBT1chr10:124380896chr10:124216423ENST00000368909+41531755_17591740.33333333333332414.0Compositional biasNote=Poly-Thr
HgeneDMBT1chr10:124380896chr10:124216423ENST00000368955+40521755_17591730.33333333333332404.0Compositional biasNote=Poly-Thr
HgeneDMBT1chr10:124380896chr10:124216423ENST00000368956+28401755_17591112.33333333333331786.0Compositional biasNote=Poly-Thr
HgeneDMBT1chr10:124339417chr10:124216422ENST00000330163+10401122_1222334.33333333333331786.0DomainSRCR 9
HgeneDMBT1chr10:124339417chr10:124216422ENST00000330163+10401251_1351334.33333333333331786.0DomainSRCR 10
HgeneDMBT1chr10:124339417chr10:124216422ENST00000330163+10401380_1480334.33333333333331786.0DomainSRCR 11
HgeneDMBT1chr10:124339417chr10:124216422ENST00000330163+10401509_1609334.33333333333331786.0DomainSRCR 12
HgeneDMBT1chr10:124339417chr10:124216422ENST00000330163+10401640_1740334.33333333333331786.0DomainSRCR 13
HgeneDMBT1chr10:124339417chr10:124216422ENST00000330163+10401766_1877334.33333333333331786.0DomainCUB 1
HgeneDMBT1chr10:124339417chr10:124216422ENST00000330163+10401883_1986334.33333333333331786.0DomainSRCR 14
HgeneDMBT1chr10:124339417chr10:124216422ENST00000330163+10402008_2117334.33333333333331786.0DomainCUB 2
HgeneDMBT1chr10:124339417chr10:124216422ENST00000330163+10402126_2381334.33333333333331786.0DomainZP
HgeneDMBT1chr10:124339417chr10:124216422ENST00000330163+1040363_463334.33333333333331786.0DomainSRCR 3
HgeneDMBT1chr10:124339417chr10:124216422ENST00000330163+1040494_594334.33333333333331786.0DomainSRCR 4
HgeneDMBT1chr10:124339417chr10:124216422ENST00000330163+1040602_702334.33333333333331786.0DomainSRCR 5
HgeneDMBT1chr10:124339417chr10:124216422ENST00000330163+1040733_833334.33333333333331786.0DomainSRCR 6
HgeneDMBT1chr10:124339417chr10:124216422ENST00000330163+1040862_962334.33333333333331786.0DomainSRCR 7
HgeneDMBT1chr10:124339417chr10:124216422ENST00000330163+1040993_1093334.33333333333331786.0DomainSRCR 8
HgeneDMBT1chr10:124339417chr10:124216422ENST00000338354+10531122_1222334.33333333333332414.0DomainSRCR 9
HgeneDMBT1chr10:124339417chr10:124216422ENST00000338354+10531251_1351334.33333333333332414.0DomainSRCR 10
HgeneDMBT1chr10:124339417chr10:124216422ENST00000338354+10531380_1480334.33333333333332414.0DomainSRCR 11
HgeneDMBT1chr10:124339417chr10:124216422ENST00000338354+10531509_1609334.33333333333332414.0DomainSRCR 12
HgeneDMBT1chr10:124339417chr10:124216422ENST00000338354+10531640_1740334.33333333333332414.0DomainSRCR 13
HgeneDMBT1chr10:124339417chr10:124216422ENST00000338354+10531766_1877334.33333333333332414.0DomainCUB 1
HgeneDMBT1chr10:124339417chr10:124216422ENST00000338354+10531883_1986334.33333333333332414.0DomainSRCR 14
HgeneDMBT1chr10:124339417chr10:124216422ENST00000338354+10532008_2117334.33333333333332414.0DomainCUB 2
HgeneDMBT1chr10:124339417chr10:124216422ENST00000338354+10532126_2381334.33333333333332414.0DomainZP
HgeneDMBT1chr10:124339417chr10:124216422ENST00000338354+1053363_463334.33333333333332414.0DomainSRCR 3
HgeneDMBT1chr10:124339417chr10:124216422ENST00000338354+1053494_594334.33333333333332414.0DomainSRCR 4
HgeneDMBT1chr10:124339417chr10:124216422ENST00000338354+1053602_702334.33333333333332414.0DomainSRCR 5
HgeneDMBT1chr10:124339417chr10:124216422ENST00000338354+1053733_833334.33333333333332414.0DomainSRCR 6
HgeneDMBT1chr10:124339417chr10:124216422ENST00000338354+1053862_962334.33333333333332414.0DomainSRCR 7
HgeneDMBT1chr10:124339417chr10:124216422ENST00000338354+1053993_1093334.33333333333332414.0DomainSRCR 8
HgeneDMBT1chr10:124339417chr10:124216422ENST00000344338+10521122_1222334.33333333333332404.0DomainSRCR 9
HgeneDMBT1chr10:124339417chr10:124216422ENST00000344338+10521251_1351334.33333333333332404.0DomainSRCR 10
HgeneDMBT1chr10:124339417chr10:124216422ENST00000344338+10521380_1480334.33333333333332404.0DomainSRCR 11
HgeneDMBT1chr10:124339417chr10:124216422ENST00000344338+10521509_1609334.33333333333332404.0DomainSRCR 12
HgeneDMBT1chr10:124339417chr10:124216422ENST00000344338+10521640_1740334.33333333333332404.0DomainSRCR 13
HgeneDMBT1chr10:124339417chr10:124216422ENST00000344338+10521766_1877334.33333333333332404.0DomainCUB 1
HgeneDMBT1chr10:124339417chr10:124216422ENST00000344338+10521883_1986334.33333333333332404.0DomainSRCR 14
HgeneDMBT1chr10:124339417chr10:124216422ENST00000344338+10522008_2117334.33333333333332404.0DomainCUB 2
HgeneDMBT1chr10:124339417chr10:124216422ENST00000344338+10522126_2381334.33333333333332404.0DomainZP
HgeneDMBT1chr10:124339417chr10:124216422ENST00000344338+1052363_463334.33333333333332404.0DomainSRCR 3
HgeneDMBT1chr10:124339417chr10:124216422ENST00000344338+1052494_594334.33333333333332404.0DomainSRCR 4
HgeneDMBT1chr10:124339417chr10:124216422ENST00000344338+1052602_702334.33333333333332404.0DomainSRCR 5
HgeneDMBT1chr10:124339417chr10:124216422ENST00000344338+1052733_833334.33333333333332404.0DomainSRCR 6
HgeneDMBT1chr10:124339417chr10:124216422ENST00000344338+1052862_962334.33333333333332404.0DomainSRCR 7
HgeneDMBT1chr10:124339417chr10:124216422ENST00000344338+1052993_1093334.33333333333332404.0DomainSRCR 8
HgeneDMBT1chr10:124339417chr10:124216422ENST00000368909+10531122_1222334.33333333333332414.0DomainSRCR 9
HgeneDMBT1chr10:124339417chr10:124216422ENST00000368909+10531251_1351334.33333333333332414.0DomainSRCR 10
HgeneDMBT1chr10:124339417chr10:124216422ENST00000368909+10531380_1480334.33333333333332414.0DomainSRCR 11
HgeneDMBT1chr10:124339417chr10:124216422ENST00000368909+10531509_1609334.33333333333332414.0DomainSRCR 12
HgeneDMBT1chr10:124339417chr10:124216422ENST00000368909+10531640_1740334.33333333333332414.0DomainSRCR 13
HgeneDMBT1chr10:124339417chr10:124216422ENST00000368909+10531766_1877334.33333333333332414.0DomainCUB 1
HgeneDMBT1chr10:124339417chr10:124216422ENST00000368909+10531883_1986334.33333333333332414.0DomainSRCR 14
HgeneDMBT1chr10:124339417chr10:124216422ENST00000368909+10532008_2117334.33333333333332414.0DomainCUB 2
HgeneDMBT1chr10:124339417chr10:124216422ENST00000368909+10532126_2381334.33333333333332414.0DomainZP
HgeneDMBT1chr10:124339417chr10:124216422ENST00000368909+1053363_463334.33333333333332414.0DomainSRCR 3
HgeneDMBT1chr10:124339417chr10:124216422ENST00000368909+1053494_594334.33333333333332414.0DomainSRCR 4
HgeneDMBT1chr10:124339417chr10:124216422ENST00000368909+1053602_702334.33333333333332414.0DomainSRCR 5
HgeneDMBT1chr10:124339417chr10:124216422ENST00000368909+1053733_833334.33333333333332414.0DomainSRCR 6
HgeneDMBT1chr10:124339417chr10:124216422ENST00000368909+1053862_962334.33333333333332414.0DomainSRCR 7
HgeneDMBT1chr10:124339417chr10:124216422ENST00000368909+1053993_1093334.33333333333332414.0DomainSRCR 8
HgeneDMBT1chr10:124339417chr10:124216422ENST00000368955+10521122_1222334.33333333333332404.0DomainSRCR 9
HgeneDMBT1chr10:124339417chr10:124216422ENST00000368955+10521251_1351334.33333333333332404.0DomainSRCR 10
HgeneDMBT1chr10:124339417chr10:124216422ENST00000368955+10521380_1480334.33333333333332404.0DomainSRCR 11
HgeneDMBT1chr10:124339417chr10:124216422ENST00000368955+10521509_1609334.33333333333332404.0DomainSRCR 12
HgeneDMBT1chr10:124339417chr10:124216422ENST00000368955+10521640_1740334.33333333333332404.0DomainSRCR 13
HgeneDMBT1chr10:124339417chr10:124216422ENST00000368955+10521766_1877334.33333333333332404.0DomainCUB 1
HgeneDMBT1chr10:124339417chr10:124216422ENST00000368955+10521883_1986334.33333333333332404.0DomainSRCR 14
HgeneDMBT1chr10:124339417chr10:124216422ENST00000368955+10522008_2117334.33333333333332404.0DomainCUB 2
HgeneDMBT1chr10:124339417chr10:124216422ENST00000368955+10522126_2381334.33333333333332404.0DomainZP
HgeneDMBT1chr10:124339417chr10:124216422ENST00000368955+1052363_463334.33333333333332404.0DomainSRCR 3
HgeneDMBT1chr10:124339417chr10:124216422ENST00000368955+1052494_594334.33333333333332404.0DomainSRCR 4
HgeneDMBT1chr10:124339417chr10:124216422ENST00000368955+1052602_702334.33333333333332404.0DomainSRCR 5
HgeneDMBT1chr10:124339417chr10:124216422ENST00000368955+1052733_833334.33333333333332404.0DomainSRCR 6
HgeneDMBT1chr10:124339417chr10:124216422ENST00000368955+1052862_962334.33333333333332404.0DomainSRCR 7
HgeneDMBT1chr10:124339417chr10:124216422ENST00000368955+1052993_1093334.33333333333332404.0DomainSRCR 8
HgeneDMBT1chr10:124339417chr10:124216422ENST00000368956+10401122_1222334.33333333333331786.0DomainSRCR 9
HgeneDMBT1chr10:124339417chr10:124216422ENST00000368956+10401251_1351334.33333333333331786.0DomainSRCR 10
HgeneDMBT1chr10:124339417chr10:124216422ENST00000368956+10401380_1480334.33333333333331786.0DomainSRCR 11
HgeneDMBT1chr10:124339417chr10:124216422ENST00000368956+10401509_1609334.33333333333331786.0DomainSRCR 12
HgeneDMBT1chr10:124339417chr10:124216422ENST00000368956+10401640_1740334.33333333333331786.0DomainSRCR 13
HgeneDMBT1chr10:124339417chr10:124216422ENST00000368956+10401766_1877334.33333333333331786.0DomainCUB 1
HgeneDMBT1chr10:124339417chr10:124216422ENST00000368956+10401883_1986334.33333333333331786.0DomainSRCR 14
HgeneDMBT1chr10:124339417chr10:124216422ENST00000368956+10402008_2117334.33333333333331786.0DomainCUB 2
HgeneDMBT1chr10:124339417chr10:124216422ENST00000368956+10402126_2381334.33333333333331786.0DomainZP
HgeneDMBT1chr10:124339417chr10:124216422ENST00000368956+1040363_463334.33333333333331786.0DomainSRCR 3
HgeneDMBT1chr10:124339417chr10:124216422ENST00000368956+1040494_594334.33333333333331786.0DomainSRCR 4
HgeneDMBT1chr10:124339417chr10:124216422ENST00000368956+1040602_702334.33333333333331786.0DomainSRCR 5
HgeneDMBT1chr10:124339417chr10:124216422ENST00000368956+1040733_833334.33333333333331786.0DomainSRCR 6
HgeneDMBT1chr10:124339417chr10:124216422ENST00000368956+1040862_962334.33333333333331786.0DomainSRCR 7
HgeneDMBT1chr10:124339417chr10:124216422ENST00000368956+1040993_1093334.33333333333331786.0DomainSRCR 8
HgeneDMBT1chr10:124380896chr10:124216422ENST00000330163+28401122_12221112.33333333333331786.0DomainSRCR 9
HgeneDMBT1chr10:124380896chr10:124216422ENST00000330163+28401251_13511112.33333333333331786.0DomainSRCR 10
HgeneDMBT1chr10:124380896chr10:124216422ENST00000330163+28401380_14801112.33333333333331786.0DomainSRCR 11
HgeneDMBT1chr10:124380896chr10:124216422ENST00000330163+28401509_16091112.33333333333331786.0DomainSRCR 12
HgeneDMBT1chr10:124380896chr10:124216422ENST00000330163+28401640_17401112.33333333333331786.0DomainSRCR 13
HgeneDMBT1chr10:124380896chr10:124216422ENST00000330163+28401766_18771112.33333333333331786.0DomainCUB 1
HgeneDMBT1chr10:124380896chr10:124216422ENST00000330163+28401883_19861112.33333333333331786.0DomainSRCR 14
HgeneDMBT1chr10:124380896chr10:124216422ENST00000330163+28402008_21171112.33333333333331786.0DomainCUB 2
HgeneDMBT1chr10:124380896chr10:124216422ENST00000330163+28402126_23811112.33333333333331786.0DomainZP
HgeneDMBT1chr10:124380896chr10:124216422ENST00000338354+41531766_18771740.33333333333332414.0DomainCUB 1
HgeneDMBT1chr10:124380896chr10:124216422ENST00000338354+41531883_19861740.33333333333332414.0DomainSRCR 14
HgeneDMBT1chr10:124380896chr10:124216422ENST00000338354+41532008_21171740.33333333333332414.0DomainCUB 2
HgeneDMBT1chr10:124380896chr10:124216422ENST00000338354+41532126_23811740.33333333333332414.0DomainZP
HgeneDMBT1chr10:124380896chr10:124216422ENST00000344338+40521640_17401730.33333333333332404.0DomainSRCR 13
HgeneDMBT1chr10:124380896chr10:124216422ENST00000344338+40521766_18771730.33333333333332404.0DomainCUB 1
HgeneDMBT1chr10:124380896chr10:124216422ENST00000344338+40521883_19861730.33333333333332404.0DomainSRCR 14
HgeneDMBT1chr10:124380896chr10:124216422ENST00000344338+40522008_21171730.33333333333332404.0DomainCUB 2
HgeneDMBT1chr10:124380896chr10:124216422ENST00000344338+40522126_23811730.33333333333332404.0DomainZP
HgeneDMBT1chr10:124380896chr10:124216422ENST00000368909+41531766_18771740.33333333333332414.0DomainCUB 1
HgeneDMBT1chr10:124380896chr10:124216422ENST00000368909+41531883_19861740.33333333333332414.0DomainSRCR 14
HgeneDMBT1chr10:124380896chr10:124216422ENST00000368909+41532008_21171740.33333333333332414.0DomainCUB 2
HgeneDMBT1chr10:124380896chr10:124216422ENST00000368909+41532126_23811740.33333333333332414.0DomainZP
HgeneDMBT1chr10:124380896chr10:124216422ENST00000368955+40521640_17401730.33333333333332404.0DomainSRCR 13
HgeneDMBT1chr10:124380896chr10:124216422ENST00000368955+40521766_18771730.33333333333332404.0DomainCUB 1
HgeneDMBT1chr10:124380896chr10:124216422ENST00000368955+40521883_19861730.33333333333332404.0DomainSRCR 14
HgeneDMBT1chr10:124380896chr10:124216422ENST00000368955+40522008_21171730.33333333333332404.0DomainCUB 2
HgeneDMBT1chr10:124380896chr10:124216422ENST00000368955+40522126_23811730.33333333333332404.0DomainZP
HgeneDMBT1chr10:124380896chr10:124216422ENST00000368956+28401122_12221112.33333333333331786.0DomainSRCR 9
HgeneDMBT1chr10:124380896chr10:124216422ENST00000368956+28401251_13511112.33333333333331786.0DomainSRCR 10
HgeneDMBT1chr10:124380896chr10:124216422ENST00000368956+28401380_14801112.33333333333331786.0DomainSRCR 11
HgeneDMBT1chr10:124380896chr10:124216422ENST00000368956+28401509_16091112.33333333333331786.0DomainSRCR 12
HgeneDMBT1chr10:124380896chr10:124216422ENST00000368956+28401640_17401112.33333333333331786.0DomainSRCR 13
HgeneDMBT1chr10:124380896chr10:124216422ENST00000368956+28401766_18771112.33333333333331786.0DomainCUB 1
HgeneDMBT1chr10:124380896chr10:124216422ENST00000368956+28401883_19861112.33333333333331786.0DomainSRCR 14
HgeneDMBT1chr10:124380896chr10:124216422ENST00000368956+28402008_21171112.33333333333331786.0DomainCUB 2
HgeneDMBT1chr10:124380896chr10:124216422ENST00000368956+28402126_23811112.33333333333331786.0DomainZP
HgeneDMBT1chr10:124380896chr10:124216423ENST00000330163+28401122_12221112.33333333333331786.0DomainSRCR 9
HgeneDMBT1chr10:124380896chr10:124216423ENST00000330163+28401251_13511112.33333333333331786.0DomainSRCR 10
HgeneDMBT1chr10:124380896chr10:124216423ENST00000330163+28401380_14801112.33333333333331786.0DomainSRCR 11
HgeneDMBT1chr10:124380896chr10:124216423ENST00000330163+28401509_16091112.33333333333331786.0DomainSRCR 12
HgeneDMBT1chr10:124380896chr10:124216423ENST00000330163+28401640_17401112.33333333333331786.0DomainSRCR 13
HgeneDMBT1chr10:124380896chr10:124216423ENST00000330163+28401766_18771112.33333333333331786.0DomainCUB 1
HgeneDMBT1chr10:124380896chr10:124216423ENST00000330163+28401883_19861112.33333333333331786.0DomainSRCR 14
HgeneDMBT1chr10:124380896chr10:124216423ENST00000330163+28402008_21171112.33333333333331786.0DomainCUB 2
HgeneDMBT1chr10:124380896chr10:124216423ENST00000330163+28402126_23811112.33333333333331786.0DomainZP
HgeneDMBT1chr10:124380896chr10:124216423ENST00000338354+41531766_18771740.33333333333332414.0DomainCUB 1
HgeneDMBT1chr10:124380896chr10:124216423ENST00000338354+41531883_19861740.33333333333332414.0DomainSRCR 14
HgeneDMBT1chr10:124380896chr10:124216423ENST00000338354+41532008_21171740.33333333333332414.0DomainCUB 2
HgeneDMBT1chr10:124380896chr10:124216423ENST00000338354+41532126_23811740.33333333333332414.0DomainZP
HgeneDMBT1chr10:124380896chr10:124216423ENST00000344338+40521640_17401730.33333333333332404.0DomainSRCR 13
HgeneDMBT1chr10:124380896chr10:124216423ENST00000344338+40521766_18771730.33333333333332404.0DomainCUB 1
HgeneDMBT1chr10:124380896chr10:124216423ENST00000344338+40521883_19861730.33333333333332404.0DomainSRCR 14
HgeneDMBT1chr10:124380896chr10:124216423ENST00000344338+40522008_21171730.33333333333332404.0DomainCUB 2
HgeneDMBT1chr10:124380896chr10:124216423ENST00000344338+40522126_23811730.33333333333332404.0DomainZP
HgeneDMBT1chr10:124380896chr10:124216423ENST00000368909+41531766_18771740.33333333333332414.0DomainCUB 1
HgeneDMBT1chr10:124380896chr10:124216423ENST00000368909+41531883_19861740.33333333333332414.0DomainSRCR 14
HgeneDMBT1chr10:124380896chr10:124216423ENST00000368909+41532008_21171740.33333333333332414.0DomainCUB 2
HgeneDMBT1chr10:124380896chr10:124216423ENST00000368909+41532126_23811740.33333333333332414.0DomainZP
HgeneDMBT1chr10:124380896chr10:124216423ENST00000368955+40521640_17401730.33333333333332404.0DomainSRCR 13
HgeneDMBT1chr10:124380896chr10:124216423ENST00000368955+40521766_18771730.33333333333332404.0DomainCUB 1
HgeneDMBT1chr10:124380896chr10:124216423ENST00000368955+40521883_19861730.33333333333332404.0DomainSRCR 14
HgeneDMBT1chr10:124380896chr10:124216423ENST00000368955+40522008_21171730.33333333333332404.0DomainCUB 2
HgeneDMBT1chr10:124380896chr10:124216423ENST00000368955+40522126_23811730.33333333333332404.0DomainZP
HgeneDMBT1chr10:124380896chr10:124216423ENST00000368956+28401122_12221112.33333333333331786.0DomainSRCR 9
HgeneDMBT1chr10:124380896chr10:124216423ENST00000368956+28401251_13511112.33333333333331786.0DomainSRCR 10
HgeneDMBT1chr10:124380896chr10:124216423ENST00000368956+28401380_14801112.33333333333331786.0DomainSRCR 11
HgeneDMBT1chr10:124380896chr10:124216423ENST00000368956+28401509_16091112.33333333333331786.0DomainSRCR 12
HgeneDMBT1chr10:124380896chr10:124216423ENST00000368956+28401640_17401112.33333333333331786.0DomainSRCR 13
HgeneDMBT1chr10:124380896chr10:124216423ENST00000368956+28401766_18771112.33333333333331786.0DomainCUB 1
HgeneDMBT1chr10:124380896chr10:124216423ENST00000368956+28401883_19861112.33333333333331786.0DomainSRCR 14
HgeneDMBT1chr10:124380896chr10:124216423ENST00000368956+28402008_21171112.33333333333331786.0DomainCUB 2
HgeneDMBT1chr10:124380896chr10:124216423ENST00000368956+28402126_23811112.33333333333331786.0DomainZP


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Fusion Protein Structures

check button PDB and CIF files of the predicted fusion proteins
* Here we show the 3D structure of the fusion proteins using Mol*. AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Model confidence is shown from the pLDDT values per residue. pLDDT corresponds to the model’s prediction of its score on the local Distance Difference Test. It is a measure of local accuracy (from AlphfaFold website). To color code individual residues, we transformed individual PDB files into CIF format.
Fusion protein PDB link (fusion AA seq ID in FusionPDB)HgeneHchrHbpHstrandTgeneTchrTbpTstrandAA seqLen(AA seq)


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pLDDT score distribution

check button pLDDT score distribution of the predicted wild-type structures of two partner proteins from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.
DMBT1_pLDDT.png
all structure
all structure
ARMS2_pLDDT.png
all structure
all structure

check button pLDDT score distribution of the predicted fusion protein structures from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.


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Ramachandran Plot of Fusion Protein Structure


check button Ramachandran plot of the torsional angles - phi (φ)and psi (ψ) - of the residues (amino acids) contained in this fusion protein peptide.
Fusion AA seq ID in FusionPDB and their Ramachandran plots

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Fusion Protein-Protein Interaction


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)
GenePPI interactors


check button Protein-protein interactors based on sequence similarity (STRING)
GeneSTRING network
DMBT1
ARMS2


check button - Retained interactions in fusion protein (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost interactions due to fusion (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs to DMBT1-ARMS2


check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

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Related Diseases to DMBT1-ARMS2


check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource