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	Fusion Gene Summary
	Fusion Gene Sample Information
	Fusion ORF Analysis
	Fusion Amino Acid Sequences
	Fusion Protein Functional Features
	Fusion Protein Structure
	pLDDT scores
	Ramachandran Plot of Fusion Protein Structure
	Fusion Protein-Protein Interaction
	Related drugs with this fusion protein
	Related disease with this fusion protein

Fusion Protein:DNM2-PDE4A

Fusion Protein Summary

Fusion gene summary

Fusion partner gene information	Fusion gene name: DNM2-PDE4A
	FusionPDB ID: 23649
	FusionGDB2.0 ID: 23649
		Hgene	Tgene
	Gene symbol	DNM2	PDE4A
	Gene ID	1785	5141
	Gene name	dynamin 2	phosphodiesterase 4A
	Synonyms	CMT2M\|CMTDI1\|CMTDIB\|DI-CMTB\|DYN2\|DYNII\|LCCS5	DPDE2\|PDE4\|PDE46
	Cytomap	19p13.2	19p13.2
	Type of gene	protein-coding	protein-coding
	Description	dynamin-2dynamin II	cAMP-specific 3',5'-cyclic phosphodiesterase 4Aphosphodiesterase 4A, cAMP-specific (duncephosphodiesterase E2 dunce homolog, Drosophilaphosphodiesterase isozyme 4
	Modification date	20200329	20200313
	UniProtAcc	P50570	.
Ensembl transtripts involved in fusion gene	ENST ids	ENST00000314646, ENST00000355667, ENST00000359692, ENST00000389253, ENST00000408974, ENST00000585892, ENST00000591819,	ENST00000592685, ENST00000293683, ENST00000344979, ENST00000352831, ENST00000380702, ENST00000440014,
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)	* DoF score	36 X 17 X 17=10404	9 X 9 X 8=648
	# samples	49	12
	** MAII score	log2(49/10404*10)=-4.40821274494042 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(12/648*10)=-2.43295940727611 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)	PubMed: DNM2 [Title/Abstract] AND PDE4A [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)	DNM2(10829079)-PDE4A(10556894), # samples:5 PDE4A(10559260)-DNM2(10837487), # samples:1
Anticipated loss of major functional domain due to fusion event.	DNM2-PDE4A seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. DNM2-PDE4A seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. DNM2-PDE4A seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. DNM2-PDE4A seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	DNM2	GO:1903526	negative regulation of membrane tubulation	18388313

Fusion gene breakpoints across DNM2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across PDE4A (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

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Fusion Gene Sample Information

Fusion gene information from FusionGDB2.0.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	LGG	TCGA-DB-A4XB-01A	DNM2	chr19	10829079	-	PDE4A	chr19	10556894	+
ChimerDB4	LGG	TCGA-DB-A4XB-01A	DNM2	chr19	10829079	+	PDE4A	chr19	10556894	+
ChimerDB4	LGG	TCGA-DB-A4XB	DNM2	chr19	10829079	+	PDE4A	chr19	10556894	+
ChimerDB4	LIHC	TCGA-BC-A216-01A	DNM2	chr19	10870487	+	PDE4A	chr19	10527560	+
ChimerDB4	OV	TCGA-61-1738-01A	DNM2	chr19	10829079	+	PDE4A	chr19	10556894	+
ChimerDB4	OV	TCGA-61-1738	DNM2	chr19	10829079	+	PDE4A	chr19	10556893	+

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Fusion ORF Analysis

Fusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000585892	DNM2	chr19	10829079	+	ENST00000592685	PDE4A	chr19	10556894	+	2694	325	164	2665	833
ENST00000585892	DNM2	chr19	10829079	+	ENST00000380702	PDE4A	chr19	10556894	+	4674	325	164	2665	833
ENST00000585892	DNM2	chr19	10829079	+	ENST00000352831	PDE4A	chr19	10556894	+	3538	325	164	2665	833
ENST00000585892	DNM2	chr19	10829079	+	ENST00000293683	PDE4A	chr19	10556894	+	2666	325	164	2665	834
ENST00000585892	DNM2	chr19	10829079	+	ENST00000440014	PDE4A	chr19	10556894	+	2666	325	164	2665	834
ENST00000314646	DNM2	chr19	10829079	+	ENST00000592685	PDE4A	chr19	10556894	+	2694	325	164	2665	833
ENST00000314646	DNM2	chr19	10829079	+	ENST00000380702	PDE4A	chr19	10556894	+	4674	325	164	2665	833
ENST00000314646	DNM2	chr19	10829079	+	ENST00000352831	PDE4A	chr19	10556894	+	3538	325	164	2665	833
ENST00000314646	DNM2	chr19	10829079	+	ENST00000293683	PDE4A	chr19	10556894	+	2666	325	164	2665	834
ENST00000314646	DNM2	chr19	10829079	+	ENST00000440014	PDE4A	chr19	10556894	+	2666	325	164	2665	834
ENST00000359692	DNM2	chr19	10829079	+	ENST00000592685	PDE4A	chr19	10556894	+	2680	311	150	2651	833
ENST00000359692	DNM2	chr19	10829079	+	ENST00000380702	PDE4A	chr19	10556894	+	4660	311	150	2651	833
ENST00000359692	DNM2	chr19	10829079	+	ENST00000352831	PDE4A	chr19	10556894	+	3524	311	150	2651	833
ENST00000359692	DNM2	chr19	10829079	+	ENST00000293683	PDE4A	chr19	10556894	+	2652	311	150	2651	833
ENST00000359692	DNM2	chr19	10829079	+	ENST00000440014	PDE4A	chr19	10556894	+	2652	311	150	2651	833
ENST00000389253	DNM2	chr19	10829079	+	ENST00000592685	PDE4A	chr19	10556894	+	2642	273	112	2613	833
ENST00000389253	DNM2	chr19	10829079	+	ENST00000380702	PDE4A	chr19	10556894	+	4622	273	112	2613	833
ENST00000389253	DNM2	chr19	10829079	+	ENST00000352831	PDE4A	chr19	10556894	+	3486	273	112	2613	833
ENST00000389253	DNM2	chr19	10829079	+	ENST00000293683	PDE4A	chr19	10556894	+	2614	273	112	2613	834
ENST00000389253	DNM2	chr19	10829079	+	ENST00000440014	PDE4A	chr19	10556894	+	2614	273	112	2613	834
ENST00000355667	DNM2	chr19	10829079	+	ENST00000592685	PDE4A	chr19	10556894	+	2610	241	80	2581	833
ENST00000355667	DNM2	chr19	10829079	+	ENST00000380702	PDE4A	chr19	10556894	+	4590	241	80	2581	833
ENST00000355667	DNM2	chr19	10829079	+	ENST00000352831	PDE4A	chr19	10556894	+	3454	241	80	2581	833
ENST00000355667	DNM2	chr19	10829079	+	ENST00000293683	PDE4A	chr19	10556894	+	2582	241	80	2581	834
ENST00000355667	DNM2	chr19	10829079	+	ENST00000440014	PDE4A	chr19	10556894	+	2582	241	80	2581	834
ENST00000408974	DNM2	chr19	10829079	+	ENST00000592685	PDE4A	chr19	10556894	+	2565	196	35	2536	833
ENST00000408974	DNM2	chr19	10829079	+	ENST00000380702	PDE4A	chr19	10556894	+	4545	196	35	2536	833
ENST00000408974	DNM2	chr19	10829079	+	ENST00000352831	PDE4A	chr19	10556894	+	3409	196	35	2536	833
ENST00000408974	DNM2	chr19	10829079	+	ENST00000293683	PDE4A	chr19	10556894	+	2537	196	35	2536	834
ENST00000408974	DNM2	chr19	10829079	+	ENST00000440014	PDE4A	chr19	10556894	+	2537	196	35	2536	834
ENST00000585892	DNM2	chr19	10829079	+	ENST00000592685	PDE4A	chr19	10556893	+	2694	325	164	2665	833
ENST00000585892	DNM2	chr19	10829079	+	ENST00000380702	PDE4A	chr19	10556893	+	4674	325	164	2665	833
ENST00000585892	DNM2	chr19	10829079	+	ENST00000352831	PDE4A	chr19	10556893	+	3538	325	164	2665	833
ENST00000585892	DNM2	chr19	10829079	+	ENST00000293683	PDE4A	chr19	10556893	+	2666	325	164	2665	834
ENST00000585892	DNM2	chr19	10829079	+	ENST00000440014	PDE4A	chr19	10556893	+	2666	325	164	2665	834
ENST00000314646	DNM2	chr19	10829079	+	ENST00000592685	PDE4A	chr19	10556893	+	2694	325	164	2665	833
ENST00000314646	DNM2	chr19	10829079	+	ENST00000380702	PDE4A	chr19	10556893	+	4674	325	164	2665	833
ENST00000314646	DNM2	chr19	10829079	+	ENST00000352831	PDE4A	chr19	10556893	+	3538	325	164	2665	833
ENST00000314646	DNM2	chr19	10829079	+	ENST00000293683	PDE4A	chr19	10556893	+	2666	325	164	2665	834
ENST00000314646	DNM2	chr19	10829079	+	ENST00000440014	PDE4A	chr19	10556893	+	2666	325	164	2665	834
ENST00000359692	DNM2	chr19	10829079	+	ENST00000592685	PDE4A	chr19	10556893	+	2680	311	150	2651	833
ENST00000359692	DNM2	chr19	10829079	+	ENST00000380702	PDE4A	chr19	10556893	+	4660	311	150	2651	833
ENST00000359692	DNM2	chr19	10829079	+	ENST00000352831	PDE4A	chr19	10556893	+	3524	311	150	2651	833
ENST00000359692	DNM2	chr19	10829079	+	ENST00000293683	PDE4A	chr19	10556893	+	2652	311	150	2651	833
ENST00000359692	DNM2	chr19	10829079	+	ENST00000440014	PDE4A	chr19	10556893	+	2652	311	150	2651	833
ENST00000389253	DNM2	chr19	10829079	+	ENST00000592685	PDE4A	chr19	10556893	+	2642	273	112	2613	833
ENST00000389253	DNM2	chr19	10829079	+	ENST00000380702	PDE4A	chr19	10556893	+	4622	273	112	2613	833
ENST00000389253	DNM2	chr19	10829079	+	ENST00000352831	PDE4A	chr19	10556893	+	3486	273	112	2613	833
ENST00000389253	DNM2	chr19	10829079	+	ENST00000293683	PDE4A	chr19	10556893	+	2614	273	112	2613	834
ENST00000389253	DNM2	chr19	10829079	+	ENST00000440014	PDE4A	chr19	10556893	+	2614	273	112	2613	834
ENST00000355667	DNM2	chr19	10829079	+	ENST00000592685	PDE4A	chr19	10556893	+	2610	241	80	2581	833
ENST00000355667	DNM2	chr19	10829079	+	ENST00000380702	PDE4A	chr19	10556893	+	4590	241	80	2581	833
ENST00000355667	DNM2	chr19	10829079	+	ENST00000352831	PDE4A	chr19	10556893	+	3454	241	80	2581	833
ENST00000355667	DNM2	chr19	10829079	+	ENST00000293683	PDE4A	chr19	10556893	+	2582	241	80	2581	834
ENST00000355667	DNM2	chr19	10829079	+	ENST00000440014	PDE4A	chr19	10556893	+	2582	241	80	2581	834
ENST00000408974	DNM2	chr19	10829079	+	ENST00000592685	PDE4A	chr19	10556893	+	2565	196	35	2536	833
ENST00000408974	DNM2	chr19	10829079	+	ENST00000380702	PDE4A	chr19	10556893	+	4545	196	35	2536	833
ENST00000408974	DNM2	chr19	10829079	+	ENST00000352831	PDE4A	chr19	10556893	+	3409	196	35	2536	833
ENST00000408974	DNM2	chr19	10829079	+	ENST00000293683	PDE4A	chr19	10556893	+	2537	196	35	2536	834
ENST00000408974	DNM2	chr19	10829079	+	ENST00000440014	PDE4A	chr19	10556893	+	2537	196	35	2536	834

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000585892	ENST00000592685	DNM2	chr19	10829079	+	PDE4A	chr19	10556894	+	0.008234146	0.9917658
ENST00000585892	ENST00000380702	DNM2	chr19	10829079	+	PDE4A	chr19	10556894	+	0.001770907	0.9982291
ENST00000585892	ENST00000352831	DNM2	chr19	10829079	+	PDE4A	chr19	10556894	+	0.003823185	0.99617684
ENST00000585892	ENST00000293683	DNM2	chr19	10829079	+	PDE4A	chr19	10556894	+	0.008749292	0.99125075
ENST00000585892	ENST00000440014	DNM2	chr19	10829079	+	PDE4A	chr19	10556894	+	0.008749292	0.99125075
ENST00000314646	ENST00000592685	DNM2	chr19	10829079	+	PDE4A	chr19	10556894	+	0.008234146	0.9917658
ENST00000314646	ENST00000380702	DNM2	chr19	10829079	+	PDE4A	chr19	10556894	+	0.001770907	0.9982291
ENST00000314646	ENST00000352831	DNM2	chr19	10829079	+	PDE4A	chr19	10556894	+	0.003823185	0.99617684
ENST00000314646	ENST00000293683	DNM2	chr19	10829079	+	PDE4A	chr19	10556894	+	0.008749292	0.99125075
ENST00000314646	ENST00000440014	DNM2	chr19	10829079	+	PDE4A	chr19	10556894	+	0.008749292	0.99125075
ENST00000359692	ENST00000592685	DNM2	chr19	10829079	+	PDE4A	chr19	10556894	+	0.007950486	0.9920495
ENST00000359692	ENST00000380702	DNM2	chr19	10829079	+	PDE4A	chr19	10556894	+	0.00170387	0.9982962
ENST00000359692	ENST00000352831	DNM2	chr19	10829079	+	PDE4A	chr19	10556894	+	0.003650875	0.9963491
ENST00000359692	ENST00000293683	DNM2	chr19	10829079	+	PDE4A	chr19	10556894	+	0.008418126	0.99158186
ENST00000359692	ENST00000440014	DNM2	chr19	10829079	+	PDE4A	chr19	10556894	+	0.008418126	0.99158186
ENST00000389253	ENST00000592685	DNM2	chr19	10829079	+	PDE4A	chr19	10556894	+	0.007763662	0.9922363
ENST00000389253	ENST00000380702	DNM2	chr19	10829079	+	PDE4A	chr19	10556894	+	0.001624271	0.99837565
ENST00000389253	ENST00000352831	DNM2	chr19	10829079	+	PDE4A	chr19	10556894	+	0.003496819	0.99650323
ENST00000389253	ENST00000293683	DNM2	chr19	10829079	+	PDE4A	chr19	10556894	+	0.008199586	0.99180037
ENST00000389253	ENST00000440014	DNM2	chr19	10829079	+	PDE4A	chr19	10556894	+	0.008199586	0.99180037
ENST00000355667	ENST00000592685	DNM2	chr19	10829079	+	PDE4A	chr19	10556894	+	0.007807829	0.9921922
ENST00000355667	ENST00000380702	DNM2	chr19	10829079	+	PDE4A	chr19	10556894	+	0.001600672	0.9983993
ENST00000355667	ENST00000352831	DNM2	chr19	10829079	+	PDE4A	chr19	10556894	+	0.003473822	0.9965262
ENST00000355667	ENST00000293683	DNM2	chr19	10829079	+	PDE4A	chr19	10556894	+	0.008243619	0.99175644
ENST00000355667	ENST00000440014	DNM2	chr19	10829079	+	PDE4A	chr19	10556894	+	0.008243619	0.99175644
ENST00000408974	ENST00000592685	DNM2	chr19	10829079	+	PDE4A	chr19	10556894	+	0.008266824	0.9917332
ENST00000408974	ENST00000380702	DNM2	chr19	10829079	+	PDE4A	chr19	10556894	+	0.001588395	0.99841154
ENST00000408974	ENST00000352831	DNM2	chr19	10829079	+	PDE4A	chr19	10556894	+	0.003500824	0.9964992
ENST00000408974	ENST00000293683	DNM2	chr19	10829079	+	PDE4A	chr19	10556894	+	0.008788185	0.99121183
ENST00000408974	ENST00000440014	DNM2	chr19	10829079	+	PDE4A	chr19	10556894	+	0.008788185	0.99121183
ENST00000585892	ENST00000592685	DNM2	chr19	10829079	+	PDE4A	chr19	10556893	+	0.008234146	0.9917658
ENST00000585892	ENST00000380702	DNM2	chr19	10829079	+	PDE4A	chr19	10556893	+	0.001770907	0.9982291
ENST00000585892	ENST00000352831	DNM2	chr19	10829079	+	PDE4A	chr19	10556893	+	0.003823185	0.99617684
ENST00000585892	ENST00000293683	DNM2	chr19	10829079	+	PDE4A	chr19	10556893	+	0.008749292	0.99125075
ENST00000585892	ENST00000440014	DNM2	chr19	10829079	+	PDE4A	chr19	10556893	+	0.008749292	0.99125075
ENST00000314646	ENST00000592685	DNM2	chr19	10829079	+	PDE4A	chr19	10556893	+	0.008234146	0.9917658
ENST00000314646	ENST00000380702	DNM2	chr19	10829079	+	PDE4A	chr19	10556893	+	0.001770907	0.9982291
ENST00000314646	ENST00000352831	DNM2	chr19	10829079	+	PDE4A	chr19	10556893	+	0.003823185	0.99617684
ENST00000314646	ENST00000293683	DNM2	chr19	10829079	+	PDE4A	chr19	10556893	+	0.008749292	0.99125075
ENST00000314646	ENST00000440014	DNM2	chr19	10829079	+	PDE4A	chr19	10556893	+	0.008749292	0.99125075
ENST00000359692	ENST00000592685	DNM2	chr19	10829079	+	PDE4A	chr19	10556893	+	0.007950486	0.9920495
ENST00000359692	ENST00000380702	DNM2	chr19	10829079	+	PDE4A	chr19	10556893	+	0.00170387	0.9982962
ENST00000359692	ENST00000352831	DNM2	chr19	10829079	+	PDE4A	chr19	10556893	+	0.003650875	0.9963491
ENST00000359692	ENST00000293683	DNM2	chr19	10829079	+	PDE4A	chr19	10556893	+	0.008418126	0.99158186
ENST00000359692	ENST00000440014	DNM2	chr19	10829079	+	PDE4A	chr19	10556893	+	0.008418126	0.99158186
ENST00000389253	ENST00000592685	DNM2	chr19	10829079	+	PDE4A	chr19	10556893	+	0.007763662	0.9922363
ENST00000389253	ENST00000380702	DNM2	chr19	10829079	+	PDE4A	chr19	10556893	+	0.001624271	0.99837565
ENST00000389253	ENST00000352831	DNM2	chr19	10829079	+	PDE4A	chr19	10556893	+	0.003496819	0.99650323
ENST00000389253	ENST00000293683	DNM2	chr19	10829079	+	PDE4A	chr19	10556893	+	0.008199586	0.99180037
ENST00000389253	ENST00000440014	DNM2	chr19	10829079	+	PDE4A	chr19	10556893	+	0.008199586	0.99180037
ENST00000355667	ENST00000592685	DNM2	chr19	10829079	+	PDE4A	chr19	10556893	+	0.007807829	0.9921922
ENST00000355667	ENST00000380702	DNM2	chr19	10829079	+	PDE4A	chr19	10556893	+	0.001600672	0.9983993
ENST00000355667	ENST00000352831	DNM2	chr19	10829079	+	PDE4A	chr19	10556893	+	0.003473822	0.9965262
ENST00000355667	ENST00000293683	DNM2	chr19	10829079	+	PDE4A	chr19	10556893	+	0.008243619	0.99175644
ENST00000355667	ENST00000440014	DNM2	chr19	10829079	+	PDE4A	chr19	10556893	+	0.008243619	0.99175644
ENST00000408974	ENST00000592685	DNM2	chr19	10829079	+	PDE4A	chr19	10556893	+	0.008266824	0.9917332
ENST00000408974	ENST00000380702	DNM2	chr19	10829079	+	PDE4A	chr19	10556893	+	0.001588395	0.99841154
ENST00000408974	ENST00000352831	DNM2	chr19	10829079	+	PDE4A	chr19	10556893	+	0.003500824	0.9964992
ENST00000408974	ENST00000293683	DNM2	chr19	10829079	+	PDE4A	chr19	10556893	+	0.008788185	0.99121183
ENST00000408974	ENST00000440014	DNM2	chr19	10829079	+	PDE4A	chr19	10556893	+	0.008788185	0.99121183

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Fusion Amino Acid Sequences

For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>23649_23649_1_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000314646_PDE4A_chr19_10556893_ENST00000293683_length(amino acids)=834AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_2_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000314646_PDE4A_chr19_10556893_ENST00000352831_length(amino acids)=833AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_3_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000314646_PDE4A_chr19_10556893_ENST00000380702_length(amino acids)=833AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_4_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000314646_PDE4A_chr19_10556893_ENST00000440014_length(amino acids)=834AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_5_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000314646_PDE4A_chr19_10556893_ENST00000592685_length(amino acids)=833AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_6_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000314646_PDE4A_chr19_10556894_ENST00000293683_length(amino acids)=834AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_7_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000314646_PDE4A_chr19_10556894_ENST00000352831_length(amino acids)=833AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_8_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000314646_PDE4A_chr19_10556894_ENST00000380702_length(amino acids)=833AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_9_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000314646_PDE4A_chr19_10556894_ENST00000440014_length(amino acids)=834AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_10_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000314646_PDE4A_chr19_10556894_ENST00000592685_length(amino acids)=833AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_11_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000355667_PDE4A_chr19_10556893_ENST00000293683_length(amino acids)=834AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_12_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000355667_PDE4A_chr19_10556893_ENST00000352831_length(amino acids)=833AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_13_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000355667_PDE4A_chr19_10556893_ENST00000380702_length(amino acids)=833AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_14_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000355667_PDE4A_chr19_10556893_ENST00000440014_length(amino acids)=834AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_15_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000355667_PDE4A_chr19_10556893_ENST00000592685_length(amino acids)=833AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_16_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000355667_PDE4A_chr19_10556894_ENST00000293683_length(amino acids)=834AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_17_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000355667_PDE4A_chr19_10556894_ENST00000352831_length(amino acids)=833AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_18_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000355667_PDE4A_chr19_10556894_ENST00000380702_length(amino acids)=833AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_19_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000355667_PDE4A_chr19_10556894_ENST00000440014_length(amino acids)=834AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_20_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000355667_PDE4A_chr19_10556894_ENST00000592685_length(amino acids)=833AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_21_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000359692_PDE4A_chr19_10556893_ENST00000293683_length(amino acids)=833AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_22_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000359692_PDE4A_chr19_10556893_ENST00000352831_length(amino acids)=833AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_23_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000359692_PDE4A_chr19_10556893_ENST00000380702_length(amino acids)=833AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_24_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000359692_PDE4A_chr19_10556893_ENST00000440014_length(amino acids)=833AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_25_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000359692_PDE4A_chr19_10556893_ENST00000592685_length(amino acids)=833AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_26_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000359692_PDE4A_chr19_10556894_ENST00000293683_length(amino acids)=833AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_27_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000359692_PDE4A_chr19_10556894_ENST00000352831_length(amino acids)=833AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_28_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000359692_PDE4A_chr19_10556894_ENST00000380702_length(amino acids)=833AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_29_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000359692_PDE4A_chr19_10556894_ENST00000440014_length(amino acids)=833AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_30_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000359692_PDE4A_chr19_10556894_ENST00000592685_length(amino acids)=833AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_31_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000389253_PDE4A_chr19_10556893_ENST00000293683_length(amino acids)=834AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_32_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000389253_PDE4A_chr19_10556893_ENST00000352831_length(amino acids)=833AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_33_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000389253_PDE4A_chr19_10556893_ENST00000380702_length(amino acids)=833AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_34_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000389253_PDE4A_chr19_10556893_ENST00000440014_length(amino acids)=834AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_35_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000389253_PDE4A_chr19_10556893_ENST00000592685_length(amino acids)=833AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_36_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000389253_PDE4A_chr19_10556894_ENST00000293683_length(amino acids)=834AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_37_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000389253_PDE4A_chr19_10556894_ENST00000352831_length(amino acids)=833AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_38_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000389253_PDE4A_chr19_10556894_ENST00000380702_length(amino acids)=833AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_39_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000389253_PDE4A_chr19_10556894_ENST00000440014_length(amino acids)=834AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_40_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000389253_PDE4A_chr19_10556894_ENST00000592685_length(amino acids)=833AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_41_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000408974_PDE4A_chr19_10556893_ENST00000293683_length(amino acids)=834AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_42_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000408974_PDE4A_chr19_10556893_ENST00000352831_length(amino acids)=833AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_43_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000408974_PDE4A_chr19_10556893_ENST00000380702_length(amino acids)=833AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_44_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000408974_PDE4A_chr19_10556893_ENST00000440014_length(amino acids)=834AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_45_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000408974_PDE4A_chr19_10556893_ENST00000592685_length(amino acids)=833AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_46_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000408974_PDE4A_chr19_10556894_ENST00000293683_length(amino acids)=834AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_47_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000408974_PDE4A_chr19_10556894_ENST00000352831_length(amino acids)=833AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_48_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000408974_PDE4A_chr19_10556894_ENST00000380702_length(amino acids)=833AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_49_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000408974_PDE4A_chr19_10556894_ENST00000440014_length(amino acids)=834AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_50_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000408974_PDE4A_chr19_10556894_ENST00000592685_length(amino acids)=833AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_51_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000585892_PDE4A_chr19_10556893_ENST00000293683_length(amino acids)=834AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_52_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000585892_PDE4A_chr19_10556893_ENST00000352831_length(amino acids)=833AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_53_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000585892_PDE4A_chr19_10556893_ENST00000380702_length(amino acids)=833AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_54_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000585892_PDE4A_chr19_10556893_ENST00000440014_length(amino acids)=834AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_55_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000585892_PDE4A_chr19_10556893_ENST00000592685_length(amino acids)=833AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_56_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000585892_PDE4A_chr19_10556894_ENST00000293683_length(amino acids)=834AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_57_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000585892_PDE4A_chr19_10556894_ENST00000352831_length(amino acids)=833AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_58_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000585892_PDE4A_chr19_10556894_ENST00000380702_length(amino acids)=833AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_59_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000585892_PDE4A_chr19_10556894_ENST00000440014_length(amino acids)=834AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

--------------------------------------------------------------

>23649_23649_60_DNM2-PDE4A_DNM2_chr19_10829079_ENST00000585892_PDE4A_chr19_10556894_ENST00000592685_length(amino acids)=833AA_BP=54
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRR
ESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARE
TLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPP
PPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVD
TMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLS
NPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI
RQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAE
LEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA

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Top

Fusion Protein Functional Features

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:10829079/chr19:10556894)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
DNM2 P50570	.
FUNCTION: Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones (By similarity). Plays an important role in vesicular trafficking processes, in particular endocytosis. Involved in cytokinesis (PubMed:12498685). Regulates maturation of apoptotic cell corpse-containing phagosomes by recruiting PIK3C3 to the phagosome membrane (By similarity). {ECO:0000250\|UniProtKB:P39052, ECO:0000250\|UniProtKB:P39054, ECO:0000269\|PubMed:12498685}.	FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page
* Minus value of BPloci means that the break pointn is located before the CDS.

- Retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000355667

38_46

53.666666666666664

871.0

Nucleotide binding

GTP

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000359692

38_46

53.666666666666664

867.0

Nucleotide binding

GTP

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000389253

38_46

53.666666666666664

871.0

Nucleotide binding

GTP

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000408974

38_46

53.666666666666664

867.0

Nucleotide binding

GTP

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000585892

38_46

53.666666666666664

870.0

Nucleotide binding

GTP

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000355667

38_46

53.666666666666664

871.0

Nucleotide binding

GTP

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000359692

38_46

53.666666666666664

867.0

Nucleotide binding

GTP

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000389253

38_46

53.666666666666664

871.0

Nucleotide binding

GTP

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000408974

38_46

53.666666666666664

867.0

Nucleotide binding

GTP

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000585892

38_46

53.666666666666664

870.0

Nucleotide binding

GTP

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000355667

38_45

53.666666666666664

871.0

Region

G1 motif

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000359692

38_45

53.666666666666664

867.0

Region

G1 motif

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000389253

38_45

53.666666666666664

871.0

Region

G1 motif

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000408974

38_45

53.666666666666664

867.0

Region

G1 motif

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000585892

38_45

53.666666666666664

870.0

Region

G1 motif

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000355667

38_45

53.666666666666664

871.0

Region

G1 motif

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000359692

38_45

53.666666666666664

867.0

Region

G1 motif

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000389253

38_45

53.666666666666664

871.0

Region

G1 motif

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000408974

38_45

53.666666666666664

867.0

Region

G1 motif

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000585892

38_45

53.666666666666664

870.0

Region

G1 motif

Tgene

PDE4A

chr19:10829079

chr19:10556893

ENST00000293683

357_686

80.66666666666667

861.0

Domain

PDEase

Tgene

PDE4A

chr19:10829079

chr19:10556893

ENST00000344979

357_686

648.0

Domain

PDEase

Tgene

PDE4A

chr19:10829079

chr19:10556893

ENST00000352831

357_686

106.66666666666667

887.0

Domain

PDEase

Tgene

PDE4A

chr19:10829079

chr19:10556893

ENST00000380702

357_686

84.66666666666667

865.0

Domain

PDEase

Tgene

PDE4A

chr19:10829079

chr19:10556893

ENST00000440014

357_686

45.666666666666664

826.0

Domain

PDEase

Tgene

PDE4A

chr19:10829079

chr19:10556893

ENST00000592685

357_686

84.66666666666667

865.0

Domain

PDEase

Tgene

PDE4A

chr19:10829079

chr19:10556894

ENST00000293683

357_686

80.66666666666667

861.0

Domain

PDEase

Tgene

PDE4A

chr19:10829079

chr19:10556894

ENST00000344979

357_686

648.0

Domain

PDEase

Tgene

PDE4A

chr19:10829079

chr19:10556894

ENST00000352831

357_686

106.66666666666667

887.0

Domain

PDEase

Tgene

PDE4A

chr19:10829079

chr19:10556894

ENST00000380702

357_686

84.66666666666667

865.0

Domain

PDEase

Tgene

PDE4A

chr19:10829079

chr19:10556894

ENST00000440014

357_686

45.666666666666664

826.0

Domain

PDEase

Tgene

PDE4A

chr19:10829079

chr19:10556894

ENST00000592685

357_686

84.66666666666667

865.0

Domain

PDEase

Tgene

PDE4A

chr19:10829079

chr19:10556893

ENST00000293683

433_437

80.66666666666667

861.0

Nucleotide binding

cAMP

Tgene

PDE4A

chr19:10829079

chr19:10556893

ENST00000344979

433_437

648.0

Nucleotide binding

cAMP

Tgene

PDE4A

chr19:10829079

chr19:10556893

ENST00000352831

433_437

106.66666666666667

887.0

Nucleotide binding

cAMP

Tgene

PDE4A

chr19:10829079

chr19:10556893

ENST00000380702

433_437

84.66666666666667

865.0

Nucleotide binding

cAMP

Tgene

PDE4A

chr19:10829079

chr19:10556893

ENST00000440014

433_437

45.666666666666664

826.0

Nucleotide binding

cAMP

Tgene

PDE4A

chr19:10829079

chr19:10556893

ENST00000592685

433_437

84.66666666666667

865.0

Nucleotide binding

cAMP

Tgene

PDE4A

chr19:10829079

chr19:10556894

ENST00000293683

433_437

80.66666666666667

861.0

Nucleotide binding

cAMP

Tgene

PDE4A

chr19:10829079

chr19:10556894

ENST00000344979

433_437

648.0

Nucleotide binding

cAMP

Tgene

PDE4A

chr19:10829079

chr19:10556894

ENST00000352831

433_437

106.66666666666667

887.0

Nucleotide binding

cAMP

Tgene

PDE4A

chr19:10829079

chr19:10556894

ENST00000380702

433_437

84.66666666666667

865.0

Nucleotide binding

cAMP

Tgene

PDE4A

chr19:10829079

chr19:10556894

ENST00000440014

433_437

45.666666666666664

826.0

Nucleotide binding

cAMP

Tgene

PDE4A

chr19:10829079

chr19:10556894

ENST00000592685

433_437

84.66666666666667

865.0

Nucleotide binding

cAMP

- Not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000355667

747_866

53.666666666666664

871.0

Compositional bias

Note=Pro-rich

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000359692

747_866

53.666666666666664

867.0

Compositional bias

Note=Pro-rich

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000389253

747_866

53.666666666666664

871.0

Compositional bias

Note=Pro-rich

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000408974

747_866

53.666666666666664

867.0

Compositional bias

Note=Pro-rich

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000585892

747_866

53.666666666666664

870.0

Compositional bias

Note=Pro-rich

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000355667

747_866

53.666666666666664

871.0

Compositional bias

Note=Pro-rich

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000359692

747_866

53.666666666666664

867.0

Compositional bias

Note=Pro-rich

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000389253

747_866

53.666666666666664

871.0

Compositional bias

Note=Pro-rich

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000408974

747_866

53.666666666666664

867.0

Compositional bias

Note=Pro-rich

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000585892

747_866

53.666666666666664

870.0

Compositional bias

Note=Pro-rich

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000355667

28_294

53.666666666666664

871.0

Domain

Dynamin-type G

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000355667

519_625

53.666666666666664

871.0

Domain

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000355667

653_744

53.666666666666664

871.0

Domain

GED

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000359692

28_294

53.666666666666664

867.0

Domain

Dynamin-type G

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000359692

519_625

53.666666666666664

867.0

Domain

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000359692

653_744

53.666666666666664

867.0

Domain

GED

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000389253

28_294

53.666666666666664

871.0

Domain

Dynamin-type G

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000389253

519_625

53.666666666666664

871.0

Domain

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000389253

653_744

53.666666666666664

871.0

Domain

GED

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000408974

28_294

53.666666666666664

867.0

Domain

Dynamin-type G

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000408974

519_625

53.666666666666664

867.0

Domain

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000408974

653_744

53.666666666666664

867.0

Domain

GED

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000585892

28_294

53.666666666666664

870.0

Domain

Dynamin-type G

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000585892

519_625

53.666666666666664

870.0

Domain

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000585892

653_744

53.666666666666664

870.0

Domain

GED

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000355667

28_294

53.666666666666664

871.0

Domain

Dynamin-type G

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000355667

519_625

53.666666666666664

871.0

Domain

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000355667

653_744

53.666666666666664

871.0

Domain

GED

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000359692

28_294

53.666666666666664

867.0

Domain

Dynamin-type G

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000359692

519_625

53.666666666666664

867.0

Domain

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000359692

653_744

53.666666666666664

867.0

Domain

GED

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000389253

28_294

53.666666666666664

871.0

Domain

Dynamin-type G

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000389253

519_625

53.666666666666664

871.0

Domain

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000389253

653_744

53.666666666666664

871.0

Domain

GED

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000408974

28_294

53.666666666666664

867.0

Domain

Dynamin-type G

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000408974

519_625

53.666666666666664

867.0

Domain

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000408974

653_744

53.666666666666664

867.0

Domain

GED

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000585892

28_294

53.666666666666664

870.0

Domain

Dynamin-type G

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000585892

519_625

53.666666666666664

870.0

Domain

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000585892

653_744

53.666666666666664

870.0

Domain

GED

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000355667

205_211

53.666666666666664

871.0

Nucleotide binding

GTP

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000355667

236_239

53.666666666666664

871.0

Nucleotide binding

GTP

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000359692

205_211

53.666666666666664

867.0

Nucleotide binding

GTP

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000359692

236_239

53.666666666666664

867.0

Nucleotide binding

GTP

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000389253

205_211

53.666666666666664

871.0

Nucleotide binding

GTP

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000389253

236_239

53.666666666666664

871.0

Nucleotide binding

GTP

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000408974

205_211

53.666666666666664

867.0

Nucleotide binding

GTP

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000408974

236_239

53.666666666666664

867.0

Nucleotide binding

GTP

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000585892

205_211

53.666666666666664

870.0

Nucleotide binding

GTP

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000585892

236_239

53.666666666666664

870.0

Nucleotide binding

GTP

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000355667

205_211

53.666666666666664

871.0

Nucleotide binding

GTP

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000355667

236_239

53.666666666666664

871.0

Nucleotide binding

GTP

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000359692

205_211

53.666666666666664

867.0

Nucleotide binding

GTP

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000359692

236_239

53.666666666666664

867.0

Nucleotide binding

GTP

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000389253

205_211

53.666666666666664

871.0

Nucleotide binding

GTP

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000389253

236_239

53.666666666666664

871.0

Nucleotide binding

GTP

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000408974

205_211

53.666666666666664

867.0

Nucleotide binding

GTP

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000408974

236_239

53.666666666666664

867.0

Nucleotide binding

GTP

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000585892

205_211

53.666666666666664

870.0

Nucleotide binding

GTP

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000585892

236_239

53.666666666666664

870.0

Nucleotide binding

GTP

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000355667

136_139

53.666666666666664

871.0

Region

G3 motif

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000355667

205_208

53.666666666666664

871.0

Region

G4 motif

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000355667

235_238

53.666666666666664

871.0

Region

G5 motif

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000355667

64_66

53.666666666666664

871.0

Region

G2 motif

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000359692

136_139

53.666666666666664

867.0

Region

G3 motif

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000359692

205_208

53.666666666666664

867.0

Region

G4 motif

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000359692

235_238

53.666666666666664

867.0

Region

G5 motif

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000359692

64_66

53.666666666666664

867.0

Region

G2 motif

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000389253

136_139

53.666666666666664

871.0

Region

G3 motif

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000389253

205_208

53.666666666666664

871.0

Region

G4 motif

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000389253

235_238

53.666666666666664

871.0

Region

G5 motif

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000389253

64_66

53.666666666666664

871.0

Region

G2 motif

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000408974

136_139

53.666666666666664

867.0

Region

G3 motif

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000408974

205_208

53.666666666666664

867.0

Region

G4 motif

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000408974

235_238

53.666666666666664

867.0

Region

G5 motif

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000408974

64_66

53.666666666666664

867.0

Region

G2 motif

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000585892

136_139

53.666666666666664

870.0

Region

G3 motif

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000585892

205_208

53.666666666666664

870.0

Region

G4 motif

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000585892

235_238

53.666666666666664

870.0

Region

G5 motif

Hgene

DNM2

chr19:10829079

chr19:10556893

ENST00000585892

64_66

53.666666666666664

870.0

Region

G2 motif

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000355667

136_139

53.666666666666664

871.0

Region

G3 motif

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000355667

205_208

53.666666666666664

871.0

Region

G4 motif

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000355667

235_238

53.666666666666664

871.0

Region

G5 motif

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000355667

64_66

53.666666666666664

871.0

Region

G2 motif

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000359692

136_139

53.666666666666664

867.0

Region

G3 motif

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000359692

205_208

53.666666666666664

867.0

Region

G4 motif

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000359692

235_238

53.666666666666664

867.0

Region

G5 motif

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000359692

64_66

53.666666666666664

867.0

Region

G2 motif

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000389253

136_139

53.666666666666664

871.0

Region

G3 motif

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000389253

205_208

53.666666666666664

871.0

Region

G4 motif

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000389253

235_238

53.666666666666664

871.0

Region

G5 motif

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000389253

64_66

53.666666666666664

871.0

Region

G2 motif

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000408974

136_139

53.666666666666664

867.0

Region

G3 motif

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000408974

205_208

53.666666666666664

867.0

Region

G4 motif

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000408974

235_238

53.666666666666664

867.0

Region

G5 motif

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000408974

64_66

53.666666666666664

867.0

Region

G2 motif

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000585892

136_139

53.666666666666664

870.0

Region

G3 motif

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000585892

205_208

53.666666666666664

870.0

Region

G4 motif

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000585892

235_238

53.666666666666664

870.0

Region

G5 motif

Hgene

DNM2

chr19:10829079

chr19:10556894

ENST00000585892

64_66

53.666666666666664

870.0

Region

G2 motif

Top

Fusion Protein Structures

PDB and CIF files of the predicted fusion proteins
* Here we show the 3D structure of the fusion proteins using Mol*. AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Model confidence is shown from the pLDDT values per residue. pLDDT corresponds to the model’s prediction of its score on the local Distance Difference Test. It is a measure of local accuracy (from AlphfaFold website). To color code individual residues, we transformed individual PDB files into CIF format.

Fusion protein PDB link (fusion AA seq ID in FusionPDB)

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

AA seq

Len(AA seq)

Top

pLDDT score distribution

pLDDT score distribution of the predicted wild-type structures of two partner proteins from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.

DNM2_pLDDT.png

PDE4A_pLDDT.png

pLDDT score distribution of the predicted fusion protein structures from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.

Top

Ramachandran Plot of Fusion Protein Structure

Ramachandran plot of the torsional angles - phi (φ)and psi (ψ) - of the residues (amino acids) contained in this fusion protein peptide.

Fusion AA seq ID in FusionPDB and their Ramachandran plots

Top

Fusion Protein-Protein Interaction

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)

Gene

PPI interactors

Protein-protein interactors based on sequence similarity (STRING)

Gene	STRING network
DNM2
PDE4A

- Retained interactions in fusion protein (protein functional feature from UniProt).

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost interactions due to fusion (protein functional feature from UniProt).

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs to DNM2-PDE4A

Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene

Tgene

Drug

Source

PMID

Top

Related Diseases to DNM2-PDE4A

Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene

Tgene

Disease

Source

PMID

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source