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Center for Computational Systems Medicine level3
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Fusion Gene Summary

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Fusion Gene Sample Information

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Fusion ORF Analysis

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Fusion Amino Acid Sequences

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Fusion Protein Functional Features

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Fusion Protein Structure

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pLDDT scores

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Ramachandran Plot of Fusion Protein Structure

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Potential Active Site Information

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Potentially Interacting Small Molecules through Virtual Screening

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Biochemical Features of Small Molecules with ADME

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Drug Toxicity Information

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Fusion Protein-Protein Interaction

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Related drugs with this fusion protein

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Related disease with this fusion protein

Fusion Protein:SLC34A2-ROS1

Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: SLC34A2-ROS1
FusionPDB ID: 82926
FusionGDB2.0 ID: 82926
HgeneTgene
Gene symbol

SLC34A2

ROS1

Gene ID

10568

6098

Gene namesolute carrier family 34 member 2ROS proto-oncogene 1, receptor tyrosine kinase
SynonymsNAPI-3B|NAPI-IIb|NPTIIb|PULAMMCF3|ROS|c-ros-1
Cytomap

4p15.2

6q22.1

Type of geneprotein-codingprotein-coding
Descriptionsodium-dependent phosphate transport protein 2Bsodium/phosphate cotransporter 2Bsolute carrier family 34 (sodium phosphate), member 2solute carrier family 34 (type II sodium/phosphate cotransporter), member 2type II sodium-dependent phosphate transporproto-oncogene tyrosine-protein kinase ROSROS proto-oncogene 1 , receptor tyrosine kinasec-ros oncogene 1 , receptor tyrosine kinaseproto-oncogene c-Ros-1transmembrane tyrosine-specific protein kinasev-ros avian UR2 sarcoma virus oncogene homolog 1
Modification date2020031320200314
UniProtAcc

O95436

P08922

Ensembl transtripts involved in fusion geneENST idsENST00000382051, ENST00000503434, 
ENST00000504570, ENST00000510033, 
ENST00000368507, ENST00000368508, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score8 X 10 X 6=48018 X 20 X 5=1800
# samples 1520
** MAII scorelog2(15/480*10)=-1.67807190511264
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(20/1800*10)=-3.16992500144231
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)

PubMed: SLC34A2 [Title/Abstract] AND ROS1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)SLC34A2(25665952)-ROS1(117650611), # samples:4
SLC34A2(25665952)-ROS1(117645580), # samples:4
Anticipated loss of major functional domain due to fusion event.SLC34A2-ROS1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
SLC34A2-ROS1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
SLC34A2-ROS1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
SLC34A2-ROS1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
SLC34A2-ROS1 seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
SLC34A2-ROS1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
SLC34A2-ROS1 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
SLC34A2-ROS1 seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF.
SLC34A2-ROS1 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
SLC34A2-ROS1 seems lost the major protein functional domain in Tgene partner, which is a kinase due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneSLC34A2

GO:0006817

phosphate ion transport

10329428|10610722|12488042

HgeneSLC34A2

GO:0030643

cellular phosphate ion homeostasis

10610722

TgeneROS1

GO:0001558

regulation of cell growth

16885344

TgeneROS1

GO:0006468

protein phosphorylation

16885344

TgeneROS1

GO:0032006

regulation of TOR signaling

16885344


check buttonFusion gene breakpoints across SLC34A2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ROS1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


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Fusion Gene Sample Information

check buttonFusion gene information from FusionGDB2.0.
check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUADTCGA-05-4426-01ASLC34A2chr4

25678323

+ROS1chr6

117645577

-
ChimerDB4LUADTCGA-05-4426-01ASLC34A2chr4

25678323

+ROS1chr6

117650608

-
ChimerDB4LUADTCGA-05-4426-01ASLC34A2chr4

25678324

+ROS1chr6

117645578

-
ChimerDB4LUADTCGA-05-4426-01ASLC34A2chr4

25678324

+ROS1chr6

117650609

-
ChimerDB4LUADTCGA-62-A46Y-01ASLC34A2chr4

25678323

+ROS1chr6

117650608

-
ChimerDB4LUADTCGA-62-A46Y-01ASLC34A2chr4

25678324

+ROS1chr6

117650609

-
ChimerDB4non small cell lung cancerEU236946SLC34A2chr4

25665952

ROS1chr6

117609655
ChimerKB3..SLC34A2chr4

25665952

+ROS1chr6

117650609

-
ChimerKB3..SLC34A2chr4

25676251

+ROS1chr6

117645578

-
ChimerKB3..SLC34A2chr4

25678323

+ROS1chr6

117650608

-
ChiTaRS5.0N/AAB795243SLC34A2chr4

25678324

+ROS1chr6

117650610

-
ChiTaRS5.0N/AEU236946SLC34A2chr4

25665952

+ROS1chr6

117650611

-
ChiTaRS5.0N/AEU236947SLC34A2chr4

25665952

+ROS1chr6

117645580

-
ChiTaRS5.0N/AFU269871SLC34A2chr4

25665952

+ROS1chr6

117650611

-
ChiTaRS5.0N/AFU269872SLC34A2chr4

25665952

+ROS1chr6

117645580

-
ChiTaRS5.0N/AHW611946SLC34A2chr4

25665952

+ROS1chr6

117650611

-
ChiTaRS5.0N/AHW611947SLC34A2chr4

25665952

+ROS1chr6

117645580

-
ChiTaRS5.0N/AJB625497SLC34A2chr4

25678324

+ROS1chr6

117650610

-
ChiTaRS5.0N/ALX092649SLC34A2chr4

25665952

+ROS1chr6

117650611

-
ChiTaRS5.0N/ALX092650SLC34A2chr4

25665952

+ROS1chr6

117645580

-


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Fusion ORF Analysis


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000504570SLC34A2chr425665952+ENST00000368508ROS1chr6117650609-2436448272243738
ENST00000504570SLC34A2chr425665952+ENST00000368507ROS1chr6117650609-2436448272243738
ENST00000382051SLC34A2chr425665952+ENST00000368508ROS1chr6117650609-241742952224739
ENST00000382051SLC34A2chr425665952+ENST00000368507ROS1chr6117650609-241742952224739
ENST00000503434SLC34A2chr425665952+ENST00000368508ROS1chr6117650609-2468480562275739
ENST00000503434SLC34A2chr425665952+ENST00000368507ROS1chr6117650609-2468480562275739
ENST00000382051SLC34A2chr425678323+ENST00000368508ROS1chr6117650608-5543355537195350543
ENST00000382051SLC34A2chr425678323+ENST00000368507ROS1chr6117650608-5543355537195350543
ENST00000382051SLC34A2chr425678324+ENST00000368508ROS1chr6117645578-5233355451672555
ENST00000382051SLC34A2chr425678324+ENST00000368507ROS1chr6117645578-5233355451672555
ENST00000382051SLC34A2chr425678324+ENST00000368508ROS1chr6117650609-5542355451672555
ENST00000382051SLC34A2chr425678324+ENST00000368507ROS1chr6117650609-5542355451672555
ENST00000382051SLC34A2chr425678323+ENST00000368508ROS1chr6117650608-5543355537195350543
ENST00000382051SLC34A2chr425678323+ENST00000368507ROS1chr6117650608-5543355537195350543
ENST00000382051SLC34A2chr425678323+ENST00000368508ROS1chr6117645577-5234355551555516
ENST00000382051SLC34A2chr425678323+ENST00000368507ROS1chr6117645577-5234355551555516
ENST00000382051SLC34A2chr425678324+ENST00000368508ROS1chr6117650610-5542355451672555
ENST00000382051SLC34A2chr425678324+ENST00000368507ROS1chr6117650610-5542355451672555
ENST00000504570SLC34A2chr425665952+ENST00000368508ROS1chr6117650611-2436448272243738
ENST00000504570SLC34A2chr425665952+ENST00000368507ROS1chr6117650611-2436448272243738
ENST00000382051SLC34A2chr425665952+ENST00000368508ROS1chr6117650611-241742952224739
ENST00000382051SLC34A2chr425665952+ENST00000368507ROS1chr6117650611-241742952224739
ENST00000503434SLC34A2chr425665952+ENST00000368508ROS1chr6117650611-2468480562275739
ENST00000503434SLC34A2chr425665952+ENST00000368507ROS1chr6117650611-2468480562275739
ENST00000504570SLC34A2chr425665952+ENST00000368508ROS1chr6117645580-2127448271934635
ENST00000504570SLC34A2chr425665952+ENST00000368507ROS1chr6117645580-2127448271934635
ENST00000382051SLC34A2chr425665952+ENST00000368508ROS1chr6117645580-210842951915636
ENST00000382051SLC34A2chr425665952+ENST00000368507ROS1chr6117645580-210842951915636
ENST00000503434SLC34A2chr425665952+ENST00000368508ROS1chr6117645580-2159480561966636
ENST00000503434SLC34A2chr425665952+ENST00000368507ROS1chr6117645580-2159480561966636

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000382051ENST00000368508SLC34A2chr425678324+ROS1chr6117645578-0.0028510920.99714893
ENST00000382051ENST00000368507SLC34A2chr425678324+ROS1chr6117645578-0.0028510920.99714893
ENST00000382051ENST00000368508SLC34A2chr425678324+ROS1chr6117650609-0.0014790080.99852103
ENST00000382051ENST00000368507SLC34A2chr425678324+ROS1chr6117650609-0.0014790080.99852103
ENST00000382051ENST00000368508SLC34A2chr425678323+ROS1chr6117650608-0.0014610320.998539
ENST00000382051ENST00000368507SLC34A2chr425678323+ROS1chr6117650608-0.0014610320.998539
ENST00000382051ENST00000368508SLC34A2chr425678323+ROS1chr6117645577-0.001990120.99800986
ENST00000382051ENST00000368507SLC34A2chr425678323+ROS1chr6117645577-0.001990120.99800986
ENST00000382051ENST00000368508SLC34A2chr425678324+ROS1chr6117650610-0.0014790080.99852103
ENST00000382051ENST00000368507SLC34A2chr425678324+ROS1chr6117650610-0.0014790080.99852103
ENST00000504570ENST00000368508SLC34A2chr425665952+ROS1chr6117650611-0.0007341070.99926585
ENST00000504570ENST00000368507SLC34A2chr425665952+ROS1chr6117650611-0.0007341070.99926585
ENST00000382051ENST00000368508SLC34A2chr425665952+ROS1chr6117650611-0.0008326330.99916744
ENST00000382051ENST00000368507SLC34A2chr425665952+ROS1chr6117650611-0.0008326330.99916744
ENST00000503434ENST00000368508SLC34A2chr425665952+ROS1chr6117650611-0.0006897650.99931026
ENST00000503434ENST00000368507SLC34A2chr425665952+ROS1chr6117650611-0.0006897650.99931026
ENST00000504570ENST00000368508SLC34A2chr425665952+ROS1chr6117645580-0.00080130.99919873
ENST00000504570ENST00000368507SLC34A2chr425665952+ROS1chr6117645580-0.00080130.99919873
ENST00000382051ENST00000368508SLC34A2chr425665952+ROS1chr6117645580-0.0012637780.9987362
ENST00000382051ENST00000368507SLC34A2chr425665952+ROS1chr6117645580-0.0012637780.9987362
ENST00000503434ENST00000368508SLC34A2chr425665952+ROS1chr6117645580-0.0006746010.9993254
ENST00000503434ENST00000368507SLC34A2chr425665952+ROS1chr6117645580-0.0006746010.9993254

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Fusion Amino Acid Sequences


check button For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>82926_82926_1_SLC34A2-ROS1_SLC34A2_chr4_25665952_ENST00000382051_ROS1_chr6_117645580_ENST00000368507_length(amino acids)=636AA_BP=141
MAAASSPAPAEGALTMAPWPELGDAQPNPDKYLEGAAGQQPTAPDKSKETNKTDNTEAPVTKIELLPSYSTATLIDEPTEVDDPWNLPTL
QDSGIKWSERDTKGKILCFFQGIGRLILLLGFLYFFVCSLDILSSAFQLVGDDFWIPETSFILTIIVGIFLVVTIPLTFVWHRRLKNQKS
AKEGVTVLINEDKELAELRGLAAGVGLANACYAIHTLPTQEEIENLPAFPREKLTLRLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKT
LKKGSTDQEKIEFLKEAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYGPLLTLVDLVDLCVDISKGCVYLE
RMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKNDYYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFGILIWEILTLGHQP
YPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQLFRNFFLNSIYKSRDEANNSGVINESFEGEDGDVI
CLNSDDIMPVALMETKNREGLNYMVLATECGQGEEKSEGPLGSQESESCGLRKEEKEPHADKDFCQEKQVAYCPSGKPEGLNYACLTHSG

--------------------------------------------------------------

>82926_82926_2_SLC34A2-ROS1_SLC34A2_chr4_25665952_ENST00000382051_ROS1_chr6_117645580_ENST00000368508_length(amino acids)=636AA_BP=141
MAAASSPAPAEGALTMAPWPELGDAQPNPDKYLEGAAGQQPTAPDKSKETNKTDNTEAPVTKIELLPSYSTATLIDEPTEVDDPWNLPTL
QDSGIKWSERDTKGKILCFFQGIGRLILLLGFLYFFVCSLDILSSAFQLVGDDFWIPETSFILTIIVGIFLVVTIPLTFVWHRRLKNQKS
AKEGVTVLINEDKELAELRGLAAGVGLANACYAIHTLPTQEEIENLPAFPREKLTLRLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKT
LKKGSTDQEKIEFLKEAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYGPLLTLVDLVDLCVDISKGCVYLE
RMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKNDYYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFGILIWEILTLGHQP
YPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQLFRNFFLNSIYKSRDEANNSGVINESFEGEDGDVI
CLNSDDIMPVALMETKNREGLNYMVLATECGQGEEKSEGPLGSQESESCGLRKEEKEPHADKDFCQEKQVAYCPSGKPEGLNYACLTHSG

--------------------------------------------------------------

>82926_82926_3_SLC34A2-ROS1_SLC34A2_chr4_25665952_ENST00000382051_ROS1_chr6_117650609_ENST00000368507_length(amino acids)=739AA_BP=141
MAAASSPAPAEGALTMAPWPELGDAQPNPDKYLEGAAGQQPTAPDKSKETNKTDNTEAPVTKIELLPSYSTATLIDEPTEVDDPWNLPTL
QDSGIKWSERDTKGKILCFFQGIGRLILLLGFLYFFVCSLDILSSAFQLVGAGVPNKPGIPKLLEGSKNSIQWEKAEDNGCRITYYILEI
RKSTSNNLQNQNLRWKMTFNGSCSSVCTWKSKNLKGIFQFRVVAANNLGFGEYSGISENIILVGDDFWIPETSFILTIIVGIFLVVTIPL
TFVWHRRLKNQKSAKEGVTVLINEDKELAELRGLAAGVGLANACYAIHTLPTQEEIENLPAFPREKLTLRLLLGSGAFGEVYEGTAVDIL
GVGSGEIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYGPLLTLVDLVD
LCVDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKNDYYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFG
ILIWEILTLGHQPYPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQLFRNFFLNSIYKSRDEANNSGV
INESFEGEDGDVICLNSDDIMPVALMETKNREGLNYMVLATECGQGEEKSEGPLGSQESESCGLRKEEKEPHADKDFCQEKQVAYCPSGK

--------------------------------------------------------------

>82926_82926_4_SLC34A2-ROS1_SLC34A2_chr4_25665952_ENST00000382051_ROS1_chr6_117650609_ENST00000368508_length(amino acids)=739AA_BP=141
MAAASSPAPAEGALTMAPWPELGDAQPNPDKYLEGAAGQQPTAPDKSKETNKTDNTEAPVTKIELLPSYSTATLIDEPTEVDDPWNLPTL
QDSGIKWSERDTKGKILCFFQGIGRLILLLGFLYFFVCSLDILSSAFQLVGAGVPNKPGIPKLLEGSKNSIQWEKAEDNGCRITYYILEI
RKSTSNNLQNQNLRWKMTFNGSCSSVCTWKSKNLKGIFQFRVVAANNLGFGEYSGISENIILVGDDFWIPETSFILTIIVGIFLVVTIPL
TFVWHRRLKNQKSAKEGVTVLINEDKELAELRGLAAGVGLANACYAIHTLPTQEEIENLPAFPREKLTLRLLLGSGAFGEVYEGTAVDIL
GVGSGEIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYGPLLTLVDLVD
LCVDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKNDYYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFG
ILIWEILTLGHQPYPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQLFRNFFLNSIYKSRDEANNSGV
INESFEGEDGDVICLNSDDIMPVALMETKNREGLNYMVLATECGQGEEKSEGPLGSQESESCGLRKEEKEPHADKDFCQEKQVAYCPSGK

--------------------------------------------------------------

>82926_82926_5_SLC34A2-ROS1_SLC34A2_chr4_25665952_ENST00000382051_ROS1_chr6_117650611_ENST00000368507_length(amino acids)=739AA_BP=141
MAAASSPAPAEGALTMAPWPELGDAQPNPDKYLEGAAGQQPTAPDKSKETNKTDNTEAPVTKIELLPSYSTATLIDEPTEVDDPWNLPTL
QDSGIKWSERDTKGKILCFFQGIGRLILLLGFLYFFVCSLDILSSAFQLVGAGVPNKPGIPKLLEGSKNSIQWEKAEDNGCRITYYILEI
RKSTSNNLQNQNLRWKMTFNGSCSSVCTWKSKNLKGIFQFRVVAANNLGFGEYSGISENIILVGDDFWIPETSFILTIIVGIFLVVTIPL
TFVWHRRLKNQKSAKEGVTVLINEDKELAELRGLAAGVGLANACYAIHTLPTQEEIENLPAFPREKLTLRLLLGSGAFGEVYEGTAVDIL
GVGSGEIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYGPLLTLVDLVD
LCVDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKNDYYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFG
ILIWEILTLGHQPYPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQLFRNFFLNSIYKSRDEANNSGV
INESFEGEDGDVICLNSDDIMPVALMETKNREGLNYMVLATECGQGEEKSEGPLGSQESESCGLRKEEKEPHADKDFCQEKQVAYCPSGK

--------------------------------------------------------------

>82926_82926_6_SLC34A2-ROS1_SLC34A2_chr4_25665952_ENST00000382051_ROS1_chr6_117650611_ENST00000368508_length(amino acids)=739AA_BP=141
MAAASSPAPAEGALTMAPWPELGDAQPNPDKYLEGAAGQQPTAPDKSKETNKTDNTEAPVTKIELLPSYSTATLIDEPTEVDDPWNLPTL
QDSGIKWSERDTKGKILCFFQGIGRLILLLGFLYFFVCSLDILSSAFQLVGAGVPNKPGIPKLLEGSKNSIQWEKAEDNGCRITYYILEI
RKSTSNNLQNQNLRWKMTFNGSCSSVCTWKSKNLKGIFQFRVVAANNLGFGEYSGISENIILVGDDFWIPETSFILTIIVGIFLVVTIPL
TFVWHRRLKNQKSAKEGVTVLINEDKELAELRGLAAGVGLANACYAIHTLPTQEEIENLPAFPREKLTLRLLLGSGAFGEVYEGTAVDIL
GVGSGEIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYGPLLTLVDLVD
LCVDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKNDYYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFG
ILIWEILTLGHQPYPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQLFRNFFLNSIYKSRDEANNSGV
INESFEGEDGDVICLNSDDIMPVALMETKNREGLNYMVLATECGQGEEKSEGPLGSQESESCGLRKEEKEPHADKDFCQEKQVAYCPSGK

--------------------------------------------------------------

>82926_82926_7_SLC34A2-ROS1_SLC34A2_chr4_25665952_ENST00000503434_ROS1_chr6_117645580_ENST00000368507_length(amino acids)=636AA_BP=141
MGSKARNLCFPSHKWTMAPWPELGDAQPNPDKYLEGAAGQQPTAPDKSKETNKNNTEAPVTKIELLPSYSTATLIDEPTEVDDPWNLPTL
QDSGIKWSERDTKGKILCFFQGIGRLILLLGFLYFFVCSLDILSSAFQLVGDDFWIPETSFILTIIVGIFLVVTIPLTFVWHRRLKNQKS
AKEGVTVLINEDKELAELRGLAAGVGLANACYAIHTLPTQEEIENLPAFPREKLTLRLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKT
LKKGSTDQEKIEFLKEAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYGPLLTLVDLVDLCVDISKGCVYLE
RMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKNDYYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFGILIWEILTLGHQP
YPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQLFRNFFLNSIYKSRDEANNSGVINESFEGEDGDVI
CLNSDDIMPVALMETKNREGLNYMVLATECGQGEEKSEGPLGSQESESCGLRKEEKEPHADKDFCQEKQVAYCPSGKPEGLNYACLTHSG

--------------------------------------------------------------

>82926_82926_8_SLC34A2-ROS1_SLC34A2_chr4_25665952_ENST00000503434_ROS1_chr6_117645580_ENST00000368508_length(amino acids)=636AA_BP=141
MGSKARNLCFPSHKWTMAPWPELGDAQPNPDKYLEGAAGQQPTAPDKSKETNKNNTEAPVTKIELLPSYSTATLIDEPTEVDDPWNLPTL
QDSGIKWSERDTKGKILCFFQGIGRLILLLGFLYFFVCSLDILSSAFQLVGDDFWIPETSFILTIIVGIFLVVTIPLTFVWHRRLKNQKS
AKEGVTVLINEDKELAELRGLAAGVGLANACYAIHTLPTQEEIENLPAFPREKLTLRLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKT
LKKGSTDQEKIEFLKEAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYGPLLTLVDLVDLCVDISKGCVYLE
RMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKNDYYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFGILIWEILTLGHQP
YPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQLFRNFFLNSIYKSRDEANNSGVINESFEGEDGDVI
CLNSDDIMPVALMETKNREGLNYMVLATECGQGEEKSEGPLGSQESESCGLRKEEKEPHADKDFCQEKQVAYCPSGKPEGLNYACLTHSG

--------------------------------------------------------------

>82926_82926_9_SLC34A2-ROS1_SLC34A2_chr4_25665952_ENST00000503434_ROS1_chr6_117650609_ENST00000368507_length(amino acids)=739AA_BP=141
MGSKARNLCFPSHKWTMAPWPELGDAQPNPDKYLEGAAGQQPTAPDKSKETNKNNTEAPVTKIELLPSYSTATLIDEPTEVDDPWNLPTL
QDSGIKWSERDTKGKILCFFQGIGRLILLLGFLYFFVCSLDILSSAFQLVGAGVPNKPGIPKLLEGSKNSIQWEKAEDNGCRITYYILEI
RKSTSNNLQNQNLRWKMTFNGSCSSVCTWKSKNLKGIFQFRVVAANNLGFGEYSGISENIILVGDDFWIPETSFILTIIVGIFLVVTIPL
TFVWHRRLKNQKSAKEGVTVLINEDKELAELRGLAAGVGLANACYAIHTLPTQEEIENLPAFPREKLTLRLLLGSGAFGEVYEGTAVDIL
GVGSGEIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYGPLLTLVDLVD
LCVDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKNDYYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFG
ILIWEILTLGHQPYPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQLFRNFFLNSIYKSRDEANNSGV
INESFEGEDGDVICLNSDDIMPVALMETKNREGLNYMVLATECGQGEEKSEGPLGSQESESCGLRKEEKEPHADKDFCQEKQVAYCPSGK

--------------------------------------------------------------

>82926_82926_10_SLC34A2-ROS1_SLC34A2_chr4_25665952_ENST00000503434_ROS1_chr6_117650609_ENST00000368508_length(amino acids)=739AA_BP=141
MGSKARNLCFPSHKWTMAPWPELGDAQPNPDKYLEGAAGQQPTAPDKSKETNKNNTEAPVTKIELLPSYSTATLIDEPTEVDDPWNLPTL
QDSGIKWSERDTKGKILCFFQGIGRLILLLGFLYFFVCSLDILSSAFQLVGAGVPNKPGIPKLLEGSKNSIQWEKAEDNGCRITYYILEI
RKSTSNNLQNQNLRWKMTFNGSCSSVCTWKSKNLKGIFQFRVVAANNLGFGEYSGISENIILVGDDFWIPETSFILTIIVGIFLVVTIPL
TFVWHRRLKNQKSAKEGVTVLINEDKELAELRGLAAGVGLANACYAIHTLPTQEEIENLPAFPREKLTLRLLLGSGAFGEVYEGTAVDIL
GVGSGEIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYGPLLTLVDLVD
LCVDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKNDYYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFG
ILIWEILTLGHQPYPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQLFRNFFLNSIYKSRDEANNSGV
INESFEGEDGDVICLNSDDIMPVALMETKNREGLNYMVLATECGQGEEKSEGPLGSQESESCGLRKEEKEPHADKDFCQEKQVAYCPSGK

--------------------------------------------------------------

>82926_82926_11_SLC34A2-ROS1_SLC34A2_chr4_25665952_ENST00000503434_ROS1_chr6_117650611_ENST00000368507_length(amino acids)=739AA_BP=141
MGSKARNLCFPSHKWTMAPWPELGDAQPNPDKYLEGAAGQQPTAPDKSKETNKNNTEAPVTKIELLPSYSTATLIDEPTEVDDPWNLPTL
QDSGIKWSERDTKGKILCFFQGIGRLILLLGFLYFFVCSLDILSSAFQLVGAGVPNKPGIPKLLEGSKNSIQWEKAEDNGCRITYYILEI
RKSTSNNLQNQNLRWKMTFNGSCSSVCTWKSKNLKGIFQFRVVAANNLGFGEYSGISENIILVGDDFWIPETSFILTIIVGIFLVVTIPL
TFVWHRRLKNQKSAKEGVTVLINEDKELAELRGLAAGVGLANACYAIHTLPTQEEIENLPAFPREKLTLRLLLGSGAFGEVYEGTAVDIL
GVGSGEIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYGPLLTLVDLVD
LCVDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKNDYYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFG
ILIWEILTLGHQPYPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQLFRNFFLNSIYKSRDEANNSGV
INESFEGEDGDVICLNSDDIMPVALMETKNREGLNYMVLATECGQGEEKSEGPLGSQESESCGLRKEEKEPHADKDFCQEKQVAYCPSGK

--------------------------------------------------------------

>82926_82926_12_SLC34A2-ROS1_SLC34A2_chr4_25665952_ENST00000503434_ROS1_chr6_117650611_ENST00000368508_length(amino acids)=739AA_BP=141
MGSKARNLCFPSHKWTMAPWPELGDAQPNPDKYLEGAAGQQPTAPDKSKETNKNNTEAPVTKIELLPSYSTATLIDEPTEVDDPWNLPTL
QDSGIKWSERDTKGKILCFFQGIGRLILLLGFLYFFVCSLDILSSAFQLVGAGVPNKPGIPKLLEGSKNSIQWEKAEDNGCRITYYILEI
RKSTSNNLQNQNLRWKMTFNGSCSSVCTWKSKNLKGIFQFRVVAANNLGFGEYSGISENIILVGDDFWIPETSFILTIIVGIFLVVTIPL
TFVWHRRLKNQKSAKEGVTVLINEDKELAELRGLAAGVGLANACYAIHTLPTQEEIENLPAFPREKLTLRLLLGSGAFGEVYEGTAVDIL
GVGSGEIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYGPLLTLVDLVD
LCVDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKNDYYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFG
ILIWEILTLGHQPYPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQLFRNFFLNSIYKSRDEANNSGV
INESFEGEDGDVICLNSDDIMPVALMETKNREGLNYMVLATECGQGEEKSEGPLGSQESESCGLRKEEKEPHADKDFCQEKQVAYCPSGK

--------------------------------------------------------------

>82926_82926_13_SLC34A2-ROS1_SLC34A2_chr4_25665952_ENST00000504570_ROS1_chr6_117645580_ENST00000368507_length(amino acids)=635AA_BP=140
MAAASSPAPAEGALTMAPWPELGDAQPNPDKYLEGAAGQQPTAPDKSKETNKNNTEAPVTKIELLPSYSTATLIDEPTEVDDPWNLPTLQ
DSGIKWSERDTKGKILCFFQGIGRLILLLGFLYFFVCSLDILSSAFQLVGDDFWIPETSFILTIIVGIFLVVTIPLTFVWHRRLKNQKSA
KEGVTVLINEDKELAELRGLAAGVGLANACYAIHTLPTQEEIENLPAFPREKLTLRLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTL
KKGSTDQEKIEFLKEAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYGPLLTLVDLVDLCVDISKGCVYLER
MHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKNDYYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFGILIWEILTLGHQPY
PAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQLFRNFFLNSIYKSRDEANNSGVINESFEGEDGDVIC
LNSDDIMPVALMETKNREGLNYMVLATECGQGEEKSEGPLGSQESESCGLRKEEKEPHADKDFCQEKQVAYCPSGKPEGLNYACLTHSGY

--------------------------------------------------------------

>82926_82926_14_SLC34A2-ROS1_SLC34A2_chr4_25665952_ENST00000504570_ROS1_chr6_117645580_ENST00000368508_length(amino acids)=635AA_BP=140
MAAASSPAPAEGALTMAPWPELGDAQPNPDKYLEGAAGQQPTAPDKSKETNKNNTEAPVTKIELLPSYSTATLIDEPTEVDDPWNLPTLQ
DSGIKWSERDTKGKILCFFQGIGRLILLLGFLYFFVCSLDILSSAFQLVGDDFWIPETSFILTIIVGIFLVVTIPLTFVWHRRLKNQKSA
KEGVTVLINEDKELAELRGLAAGVGLANACYAIHTLPTQEEIENLPAFPREKLTLRLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTL
KKGSTDQEKIEFLKEAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYGPLLTLVDLVDLCVDISKGCVYLER
MHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKNDYYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFGILIWEILTLGHQPY
PAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQLFRNFFLNSIYKSRDEANNSGVINESFEGEDGDVIC
LNSDDIMPVALMETKNREGLNYMVLATECGQGEEKSEGPLGSQESESCGLRKEEKEPHADKDFCQEKQVAYCPSGKPEGLNYACLTHSGY

--------------------------------------------------------------

>82926_82926_15_SLC34A2-ROS1_SLC34A2_chr4_25665952_ENST00000504570_ROS1_chr6_117650609_ENST00000368507_length(amino acids)=738AA_BP=140
MAAASSPAPAEGALTMAPWPELGDAQPNPDKYLEGAAGQQPTAPDKSKETNKNNTEAPVTKIELLPSYSTATLIDEPTEVDDPWNLPTLQ
DSGIKWSERDTKGKILCFFQGIGRLILLLGFLYFFVCSLDILSSAFQLVGAGVPNKPGIPKLLEGSKNSIQWEKAEDNGCRITYYILEIR
KSTSNNLQNQNLRWKMTFNGSCSSVCTWKSKNLKGIFQFRVVAANNLGFGEYSGISENIILVGDDFWIPETSFILTIIVGIFLVVTIPLT
FVWHRRLKNQKSAKEGVTVLINEDKELAELRGLAAGVGLANACYAIHTLPTQEEIENLPAFPREKLTLRLLLGSGAFGEVYEGTAVDILG
VGSGEIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYGPLLTLVDLVDL
CVDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKNDYYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFGI
LIWEILTLGHQPYPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQLFRNFFLNSIYKSRDEANNSGVI
NESFEGEDGDVICLNSDDIMPVALMETKNREGLNYMVLATECGQGEEKSEGPLGSQESESCGLRKEEKEPHADKDFCQEKQVAYCPSGKP

--------------------------------------------------------------

>82926_82926_16_SLC34A2-ROS1_SLC34A2_chr4_25665952_ENST00000504570_ROS1_chr6_117650609_ENST00000368508_length(amino acids)=738AA_BP=140
MAAASSPAPAEGALTMAPWPELGDAQPNPDKYLEGAAGQQPTAPDKSKETNKNNTEAPVTKIELLPSYSTATLIDEPTEVDDPWNLPTLQ
DSGIKWSERDTKGKILCFFQGIGRLILLLGFLYFFVCSLDILSSAFQLVGAGVPNKPGIPKLLEGSKNSIQWEKAEDNGCRITYYILEIR
KSTSNNLQNQNLRWKMTFNGSCSSVCTWKSKNLKGIFQFRVVAANNLGFGEYSGISENIILVGDDFWIPETSFILTIIVGIFLVVTIPLT
FVWHRRLKNQKSAKEGVTVLINEDKELAELRGLAAGVGLANACYAIHTLPTQEEIENLPAFPREKLTLRLLLGSGAFGEVYEGTAVDILG
VGSGEIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYGPLLTLVDLVDL
CVDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKNDYYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFGI
LIWEILTLGHQPYPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQLFRNFFLNSIYKSRDEANNSGVI
NESFEGEDGDVICLNSDDIMPVALMETKNREGLNYMVLATECGQGEEKSEGPLGSQESESCGLRKEEKEPHADKDFCQEKQVAYCPSGKP

--------------------------------------------------------------

>82926_82926_17_SLC34A2-ROS1_SLC34A2_chr4_25665952_ENST00000504570_ROS1_chr6_117650611_ENST00000368507_length(amino acids)=738AA_BP=140
MAAASSPAPAEGALTMAPWPELGDAQPNPDKYLEGAAGQQPTAPDKSKETNKNNTEAPVTKIELLPSYSTATLIDEPTEVDDPWNLPTLQ
DSGIKWSERDTKGKILCFFQGIGRLILLLGFLYFFVCSLDILSSAFQLVGAGVPNKPGIPKLLEGSKNSIQWEKAEDNGCRITYYILEIR
KSTSNNLQNQNLRWKMTFNGSCSSVCTWKSKNLKGIFQFRVVAANNLGFGEYSGISENIILVGDDFWIPETSFILTIIVGIFLVVTIPLT
FVWHRRLKNQKSAKEGVTVLINEDKELAELRGLAAGVGLANACYAIHTLPTQEEIENLPAFPREKLTLRLLLGSGAFGEVYEGTAVDILG
VGSGEIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYGPLLTLVDLVDL
CVDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKNDYYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFGI
LIWEILTLGHQPYPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQLFRNFFLNSIYKSRDEANNSGVI
NESFEGEDGDVICLNSDDIMPVALMETKNREGLNYMVLATECGQGEEKSEGPLGSQESESCGLRKEEKEPHADKDFCQEKQVAYCPSGKP

--------------------------------------------------------------

>82926_82926_18_SLC34A2-ROS1_SLC34A2_chr4_25665952_ENST00000504570_ROS1_chr6_117650611_ENST00000368508_length(amino acids)=738AA_BP=140
MAAASSPAPAEGALTMAPWPELGDAQPNPDKYLEGAAGQQPTAPDKSKETNKNNTEAPVTKIELLPSYSTATLIDEPTEVDDPWNLPTLQ
DSGIKWSERDTKGKILCFFQGIGRLILLLGFLYFFVCSLDILSSAFQLVGAGVPNKPGIPKLLEGSKNSIQWEKAEDNGCRITYYILEIR
KSTSNNLQNQNLRWKMTFNGSCSSVCTWKSKNLKGIFQFRVVAANNLGFGEYSGISENIILVGDDFWIPETSFILTIIVGIFLVVTIPLT
FVWHRRLKNQKSAKEGVTVLINEDKELAELRGLAAGVGLANACYAIHTLPTQEEIENLPAFPREKLTLRLLLGSGAFGEVYEGTAVDILG
VGSGEIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYGPLLTLVDLVDL
CVDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKNDYYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFGI
LIWEILTLGHQPYPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQLFRNFFLNSIYKSRDEANNSGVI
NESFEGEDGDVICLNSDDIMPVALMETKNREGLNYMVLATECGQGEEKSEGPLGSQESESCGLRKEEKEPHADKDFCQEKQVAYCPSGKP

--------------------------------------------------------------

>82926_82926_19_SLC34A2-ROS1_SLC34A2_chr4_25678323_ENST00000382051_ROS1_chr6_117645577_ENST00000368507_length(amino acids)=516AA_BP=
MAAASSPAPAEGALTMAPWPELGDAQPNPDKYLEGAAGQQPTAPDKSKETNKTDNTEAPVTKIELLPSYSTATLIDEPTEVDDPWNLPTL
QDSGIKWSERDTKGKILCFFQGIGRLILLLGFLYFFVCSLDILSSAFQLVGGKMAGQFFSNSSIMSNPLLGLVIGVLVTVLVQSSSTSTS
IVVSMVSSSLLTVRAAIPIIMGANIGTSITNTIVALMQVGDRSEFRRAFAGATVHDFFNWLSVLVLLPVEVATHYLEIITQLIVESFHFK
NGEDAPDLLKVITKPFTKLIVQLDKKVISQIAMNDEKAKNKSLVKIWCKTFTNKTQINVTVPSTANCTSPSLCWTDGIQNWTMKNVTYKE
NIAKCQHIFVNFHLPDLAVGTILLILSLLVLCGCLIMIVKILGSVLKGQVATVIKKTINTDFPFPFAWLTGYLAILVGAGMTFIVQSSSV

--------------------------------------------------------------

>82926_82926_20_SLC34A2-ROS1_SLC34A2_chr4_25678323_ENST00000382051_ROS1_chr6_117645577_ENST00000368508_length(amino acids)=516AA_BP=
MAAASSPAPAEGALTMAPWPELGDAQPNPDKYLEGAAGQQPTAPDKSKETNKTDNTEAPVTKIELLPSYSTATLIDEPTEVDDPWNLPTL
QDSGIKWSERDTKGKILCFFQGIGRLILLLGFLYFFVCSLDILSSAFQLVGGKMAGQFFSNSSIMSNPLLGLVIGVLVTVLVQSSSTSTS
IVVSMVSSSLLTVRAAIPIIMGANIGTSITNTIVALMQVGDRSEFRRAFAGATVHDFFNWLSVLVLLPVEVATHYLEIITQLIVESFHFK
NGEDAPDLLKVITKPFTKLIVQLDKKVISQIAMNDEKAKNKSLVKIWCKTFTNKTQINVTVPSTANCTSPSLCWTDGIQNWTMKNVTYKE
NIAKCQHIFVNFHLPDLAVGTILLILSLLVLCGCLIMIVKILGSVLKGQVATVIKKTINTDFPFPFAWLTGYLAILVGAGMTFIVQSSSV

--------------------------------------------------------------

>82926_82926_21_SLC34A2-ROS1_SLC34A2_chr4_25678323_ENST00000382051_ROS1_chr6_117650608_ENST00000368507_length(amino acids)=543AA_BP=
MTFNGSCSSVCTWKSKNLKGIFQFRVVAANNLGFGEYSGISENIILVGDDFWIPETSFILTIIVGIFLVVTIPLTFVWHRRLKNQKSAKE
GVTVLINEDKELAELRGLAAGVGLANACYAIHTLPTQEEIENLPAFPREKLTLRLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKK
GSTDQEKIEFLKEAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYGPLLTLVDLVDLCVDISKGCVYLERMH
FIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKNDYYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFGILIWEILTLGHQPYPA
HSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQLFRNFFLNSIYKSRDEANNSGVINESFEGEDGDVICLN
SDDIMPVALMETKNREGLNYMVLATECGQGEEKSEGPLGSQESESCGLRKEEKEPHADKDFCQEKQVAYCPSGKPEGLNYACLTHSGYGD

--------------------------------------------------------------

>82926_82926_22_SLC34A2-ROS1_SLC34A2_chr4_25678323_ENST00000382051_ROS1_chr6_117650608_ENST00000368508_length(amino acids)=543AA_BP=
MTFNGSCSSVCTWKSKNLKGIFQFRVVAANNLGFGEYSGISENIILVGDDFWIPETSFILTIIVGIFLVVTIPLTFVWHRRLKNQKSAKE
GVTVLINEDKELAELRGLAAGVGLANACYAIHTLPTQEEIENLPAFPREKLTLRLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKK
GSTDQEKIEFLKEAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYGPLLTLVDLVDLCVDISKGCVYLERMH
FIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKNDYYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFGILIWEILTLGHQPYPA
HSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQLFRNFFLNSIYKSRDEANNSGVINESFEGEDGDVICLN
SDDIMPVALMETKNREGLNYMVLATECGQGEEKSEGPLGSQESESCGLRKEEKEPHADKDFCQEKQVAYCPSGKPEGLNYACLTHSGYGD

--------------------------------------------------------------

>82926_82926_23_SLC34A2-ROS1_SLC34A2_chr4_25678324_ENST00000382051_ROS1_chr6_117645578_ENST00000368507_length(amino acids)=555AA_BP=
MAAASSPAPAEGALTMAPWPELGDAQPNPDKYLEGAAGQQPTAPDKSKETNKTDNTEAPVTKIELLPSYSTATLIDEPTEVDDPWNLPTL
QDSGIKWSERDTKGKILCFFQGIGRLILLLGFLYFFVCSLDILSSAFQLVGGKMAGQFFSNSSIMSNPLLGLVIGVLVTVLVQSSSTSTS
IVVSMVSSSLLTVRAAIPIIMGANIGTSITNTIVALMQVGDRSEFRRAFAGATVHDFFNWLSVLVLLPVEVATHYLEIITQLIVESFHFK
NGEDAPDLLKVITKPFTKLIVQLDKKVISQIAMNDEKAKNKSLVKIWCKTFTNKTQINVTVPSTANCTSPSLCWTDGIQNWTMKNVTYKE
NIAKCQHIFVNFHLPDLAVGTILLILSLLVLCGCLIMIVKILGSVLKGQVATVIKKTINTDFPFPFAWLTGYLAILVGAGMTFIVQSSSV
FTSALTPLIGIGVITIERAYPLTLGSNIGTTTTAILAALASPGNALRSSLQVRSLPRTQRPNARPCRGRPRLSGMGGWSLSFACSPPSHF

--------------------------------------------------------------

>82926_82926_24_SLC34A2-ROS1_SLC34A2_chr4_25678324_ENST00000382051_ROS1_chr6_117645578_ENST00000368508_length(amino acids)=555AA_BP=
MAAASSPAPAEGALTMAPWPELGDAQPNPDKYLEGAAGQQPTAPDKSKETNKTDNTEAPVTKIELLPSYSTATLIDEPTEVDDPWNLPTL
QDSGIKWSERDTKGKILCFFQGIGRLILLLGFLYFFVCSLDILSSAFQLVGGKMAGQFFSNSSIMSNPLLGLVIGVLVTVLVQSSSTSTS
IVVSMVSSSLLTVRAAIPIIMGANIGTSITNTIVALMQVGDRSEFRRAFAGATVHDFFNWLSVLVLLPVEVATHYLEIITQLIVESFHFK
NGEDAPDLLKVITKPFTKLIVQLDKKVISQIAMNDEKAKNKSLVKIWCKTFTNKTQINVTVPSTANCTSPSLCWTDGIQNWTMKNVTYKE
NIAKCQHIFVNFHLPDLAVGTILLILSLLVLCGCLIMIVKILGSVLKGQVATVIKKTINTDFPFPFAWLTGYLAILVGAGMTFIVQSSSV
FTSALTPLIGIGVITIERAYPLTLGSNIGTTTTAILAALASPGNALRSSLQVRSLPRTQRPNARPCRGRPRLSGMGGWSLSFACSPPSHF

--------------------------------------------------------------

>82926_82926_25_SLC34A2-ROS1_SLC34A2_chr4_25678324_ENST00000382051_ROS1_chr6_117650609_ENST00000368507_length(amino acids)=555AA_BP=
MAAASSPAPAEGALTMAPWPELGDAQPNPDKYLEGAAGQQPTAPDKSKETNKTDNTEAPVTKIELLPSYSTATLIDEPTEVDDPWNLPTL
QDSGIKWSERDTKGKILCFFQGIGRLILLLGFLYFFVCSLDILSSAFQLVGGKMAGQFFSNSSIMSNPLLGLVIGVLVTVLVQSSSTSTS
IVVSMVSSSLLTVRAAIPIIMGANIGTSITNTIVALMQVGDRSEFRRAFAGATVHDFFNWLSVLVLLPVEVATHYLEIITQLIVESFHFK
NGEDAPDLLKVITKPFTKLIVQLDKKVISQIAMNDEKAKNKSLVKIWCKTFTNKTQINVTVPSTANCTSPSLCWTDGIQNWTMKNVTYKE
NIAKCQHIFVNFHLPDLAVGTILLILSLLVLCGCLIMIVKILGSVLKGQVATVIKKTINTDFPFPFAWLTGYLAILVGAGMTFIVQSSSV
FTSALTPLIGIGVITIERAYPLTLGSNIGTTTTAILAALASPGNALRSSLQVRSLPRTQRPNARPCRGRPRLSGMGGWSLSFACSPPSHF

--------------------------------------------------------------

>82926_82926_26_SLC34A2-ROS1_SLC34A2_chr4_25678324_ENST00000382051_ROS1_chr6_117650609_ENST00000368508_length(amino acids)=555AA_BP=
MAAASSPAPAEGALTMAPWPELGDAQPNPDKYLEGAAGQQPTAPDKSKETNKTDNTEAPVTKIELLPSYSTATLIDEPTEVDDPWNLPTL
QDSGIKWSERDTKGKILCFFQGIGRLILLLGFLYFFVCSLDILSSAFQLVGGKMAGQFFSNSSIMSNPLLGLVIGVLVTVLVQSSSTSTS
IVVSMVSSSLLTVRAAIPIIMGANIGTSITNTIVALMQVGDRSEFRRAFAGATVHDFFNWLSVLVLLPVEVATHYLEIITQLIVESFHFK
NGEDAPDLLKVITKPFTKLIVQLDKKVISQIAMNDEKAKNKSLVKIWCKTFTNKTQINVTVPSTANCTSPSLCWTDGIQNWTMKNVTYKE
NIAKCQHIFVNFHLPDLAVGTILLILSLLVLCGCLIMIVKILGSVLKGQVATVIKKTINTDFPFPFAWLTGYLAILVGAGMTFIVQSSSV
FTSALTPLIGIGVITIERAYPLTLGSNIGTTTTAILAALASPGNALRSSLQVRSLPRTQRPNARPCRGRPRLSGMGGWSLSFACSPPSHF

--------------------------------------------------------------

>82926_82926_27_SLC34A2-ROS1_SLC34A2_chr4_25678324_ENST00000382051_ROS1_chr6_117650610_ENST00000368507_length(amino acids)=555AA_BP=
MAAASSPAPAEGALTMAPWPELGDAQPNPDKYLEGAAGQQPTAPDKSKETNKTDNTEAPVTKIELLPSYSTATLIDEPTEVDDPWNLPTL
QDSGIKWSERDTKGKILCFFQGIGRLILLLGFLYFFVCSLDILSSAFQLVGGKMAGQFFSNSSIMSNPLLGLVIGVLVTVLVQSSSTSTS
IVVSMVSSSLLTVRAAIPIIMGANIGTSITNTIVALMQVGDRSEFRRAFAGATVHDFFNWLSVLVLLPVEVATHYLEIITQLIVESFHFK
NGEDAPDLLKVITKPFTKLIVQLDKKVISQIAMNDEKAKNKSLVKIWCKTFTNKTQINVTVPSTANCTSPSLCWTDGIQNWTMKNVTYKE
NIAKCQHIFVNFHLPDLAVGTILLILSLLVLCGCLIMIVKILGSVLKGQVATVIKKTINTDFPFPFAWLTGYLAILVGAGMTFIVQSSSV
FTSALTPLIGIGVITIERAYPLTLGSNIGTTTTAILAALASPGNALRSSLQVRSLPRTQRPNARPCRGRPRLSGMGGWSLSFACSPPSHF

--------------------------------------------------------------

>82926_82926_28_SLC34A2-ROS1_SLC34A2_chr4_25678324_ENST00000382051_ROS1_chr6_117650610_ENST00000368508_length(amino acids)=555AA_BP=
MAAASSPAPAEGALTMAPWPELGDAQPNPDKYLEGAAGQQPTAPDKSKETNKTDNTEAPVTKIELLPSYSTATLIDEPTEVDDPWNLPTL
QDSGIKWSERDTKGKILCFFQGIGRLILLLGFLYFFVCSLDILSSAFQLVGGKMAGQFFSNSSIMSNPLLGLVIGVLVTVLVQSSSTSTS
IVVSMVSSSLLTVRAAIPIIMGANIGTSITNTIVALMQVGDRSEFRRAFAGATVHDFFNWLSVLVLLPVEVATHYLEIITQLIVESFHFK
NGEDAPDLLKVITKPFTKLIVQLDKKVISQIAMNDEKAKNKSLVKIWCKTFTNKTQINVTVPSTANCTSPSLCWTDGIQNWTMKNVTYKE
NIAKCQHIFVNFHLPDLAVGTILLILSLLVLCGCLIMIVKILGSVLKGQVATVIKKTINTDFPFPFAWLTGYLAILVGAGMTFIVQSSSV
FTSALTPLIGIGVITIERAYPLTLGSNIGTTTTAILAALASPGNALRSSLQVRSLPRTQRPNARPCRGRPRLSGMGGWSLSFACSPPSHF

--------------------------------------------------------------

Top

Fusion Protein Functional Features


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr4:25665952/chr6:117650611)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
SLC34A2

O95436

ROS1

P08922

FUNCTION: May be involved in actively transporting phosphate into cells via Na(+) cotransport. It may be the main phosphate transport protein in the intestinal brush border membrane. May have a role in the synthesis of surfactant in lungs' alveoli.FUNCTION: Orphan receptor tyrosine kinase (RTK) that plays a role in epithelial cell differentiation and regionalization of the proximal epididymal epithelium. May activate several downstream signaling pathways related to cell differentiation, proliferation, growth and survival including the PI3 kinase-mTOR signaling pathway. Mediates the phosphorylation of PTPN11, an activator of this pathway. May also phosphorylate and activate the transcription factor STAT3 to control anchorage-independent cell growth. Mediates the phosphorylation and the activation of VAV3, a guanine nucleotide exchange factor regulating cell morphology. May activate other downstream signaling proteins including AKT1, MAPK1, MAPK3, IRS1 and PLCG2. {ECO:0000269|PubMed:11094073, ECO:0000269|PubMed:16885344}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

* Minus value of BPloci means that the break pointn is located before the CDS.
- Retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000382051+4131_100126.33333333333333691.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000503434+4131_100125.33333333333333690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000504570+4131_100125.33333333333333690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000382051+4131_100126.33333333333333691.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000503434+4131_100125.33333333333333690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000504570+4131_100125.33333333333333690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000382051+413101_121126.33333333333333691.0TransmembraneHelical%3B Name%3DM1
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000503434+413101_121125.33333333333333690.0TransmembraneHelical%3B Name%3DM1
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000504570+413101_121125.33333333333333690.0TransmembraneHelical%3B Name%3DM1
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000382051+413101_121126.33333333333333691.0TransmembraneHelical%3B Name%3DM1
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000503434+413101_121125.33333333333333690.0TransmembraneHelical%3B Name%3DM1
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000504570+413101_121125.33333333333333690.0TransmembraneHelical%3B Name%3DM1
TgeneROS1chr4:25665952chr6:117645580ENST0000036850832431945_22221852.33333333333332348.0DomainProtein kinase
TgeneROS1chr4:25665952chr6:117650611ENST0000036850830431752_18541749.33333333333332348.0DomainFibronectin type-III 9
TgeneROS1chr4:25665952chr6:117650611ENST0000036850830431945_22221749.33333333333332348.0DomainProtein kinase
TgeneROS1chr4:25678323chr6:117645577ENST0000036850832431945_22221852.33333333333332348.0DomainProtein kinase
TgeneROS1chr4:25678323chr6:117650608ENST0000036850830431752_18541749.33333333333332348.0DomainFibronectin type-III 9
TgeneROS1chr4:25678323chr6:117650608ENST0000036850830431945_22221749.33333333333332348.0DomainProtein kinase
TgeneROS1chr4:25678324chr6:117645578ENST0000036850832431945_22221852.33333333333332348.0DomainProtein kinase
TgeneROS1chr4:25678324chr6:117650609ENST0000036850830431752_18541749.33333333333332348.0DomainFibronectin type-III 9
TgeneROS1chr4:25678324chr6:117650609ENST0000036850830431945_22221749.33333333333332348.0DomainProtein kinase
TgeneROS1chr4:25678324chr6:117650610ENST0000036850830431752_18541749.33333333333332348.0DomainFibronectin type-III 9
TgeneROS1chr4:25678324chr6:117650610ENST0000036850830431945_22221749.33333333333332348.0DomainProtein kinase
TgeneROS1chr4:25665952chr6:117645580ENST0000036850832431951_19591852.33333333333332348.0Nucleotide bindingATP
TgeneROS1chr4:25665952chr6:117650611ENST0000036850830431951_19591749.33333333333332348.0Nucleotide bindingATP
TgeneROS1chr4:25678323chr6:117645577ENST0000036850832431951_19591852.33333333333332348.0Nucleotide bindingATP
TgeneROS1chr4:25678323chr6:117650608ENST0000036850830431951_19591749.33333333333332348.0Nucleotide bindingATP
TgeneROS1chr4:25678324chr6:117645578ENST0000036850832431951_19591852.33333333333332348.0Nucleotide bindingATP
TgeneROS1chr4:25678324chr6:117650609ENST0000036850830431951_19591749.33333333333332348.0Nucleotide bindingATP
TgeneROS1chr4:25678324chr6:117650610ENST0000036850830431951_19591749.33333333333332348.0Nucleotide bindingATP
TgeneROS1chr4:25665952chr6:117645580ENST0000036850832431883_23471852.33333333333332348.0Topological domainCytoplasmic
TgeneROS1chr4:25665952chr6:117650611ENST0000036850830431883_23471749.33333333333332348.0Topological domainCytoplasmic
TgeneROS1chr4:25678323chr6:117645577ENST0000036850832431883_23471852.33333333333332348.0Topological domainCytoplasmic
TgeneROS1chr4:25678323chr6:117650608ENST0000036850830431883_23471749.33333333333332348.0Topological domainCytoplasmic
TgeneROS1chr4:25678324chr6:117645578ENST0000036850832431883_23471852.33333333333332348.0Topological domainCytoplasmic
TgeneROS1chr4:25678324chr6:117650609ENST0000036850830431883_23471749.33333333333332348.0Topological domainCytoplasmic
TgeneROS1chr4:25678324chr6:117650610ENST0000036850830431883_23471749.33333333333332348.0Topological domainCytoplasmic
TgeneROS1chr4:25665952chr6:117645580ENST0000036850832431860_18821852.33333333333332348.0TransmembraneHelical
TgeneROS1chr4:25665952chr6:117650611ENST0000036850830431860_18821749.33333333333332348.0TransmembraneHelical
TgeneROS1chr4:25678323chr6:117645577ENST0000036850832431860_18821852.33333333333332348.0TransmembraneHelical
TgeneROS1chr4:25678323chr6:117650608ENST0000036850830431860_18821749.33333333333332348.0TransmembraneHelical
TgeneROS1chr4:25678324chr6:117645578ENST0000036850832431860_18821852.33333333333332348.0TransmembraneHelical
TgeneROS1chr4:25678324chr6:117650609ENST0000036850830431860_18821749.33333333333332348.0TransmembraneHelical
TgeneROS1chr4:25678324chr6:117650610ENST0000036850830431860_18821749.33333333333332348.0TransmembraneHelical

- Not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000382051+413464_467126.33333333333333691.0Compositional biasNote=Poly-Thr
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000382051+413612_644126.33333333333333691.0Compositional biasNote=Cys-rich
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000503434+413464_467125.33333333333333690.0Compositional biasNote=Poly-Thr
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000503434+413612_644125.33333333333333690.0Compositional biasNote=Cys-rich
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000504570+413464_467125.33333333333333690.0Compositional biasNote=Poly-Thr
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000504570+413612_644125.33333333333333690.0Compositional biasNote=Cys-rich
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000382051+413464_467126.33333333333333691.0Compositional biasNote=Poly-Thr
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000382051+413612_644126.33333333333333691.0Compositional biasNote=Cys-rich
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000503434+413464_467125.33333333333333690.0Compositional biasNote=Poly-Thr
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000503434+413612_644125.33333333333333690.0Compositional biasNote=Cys-rich
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000504570+413464_467125.33333333333333690.0Compositional biasNote=Poly-Thr
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000504570+413612_644125.33333333333333690.0Compositional biasNote=Cys-rich
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000382051+113464_4670691.0Compositional biasNote=Poly-Thr
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000382051+113612_6440691.0Compositional biasNote=Cys-rich
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000503434+113464_4670690.0Compositional biasNote=Poly-Thr
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000503434+113612_6440690.0Compositional biasNote=Cys-rich
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000504570+113464_4670690.0Compositional biasNote=Poly-Thr
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000504570+113612_6440690.0Compositional biasNote=Cys-rich
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000382051+113464_4670691.0Compositional biasNote=Poly-Thr
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000382051+113612_6440691.0Compositional biasNote=Cys-rich
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000503434+113464_4670690.0Compositional biasNote=Poly-Thr
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000503434+113612_6440690.0Compositional biasNote=Cys-rich
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000504570+113464_4670690.0Compositional biasNote=Poly-Thr
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000504570+113612_6440690.0Compositional biasNote=Cys-rich
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000382051+113464_4670691.0Compositional biasNote=Poly-Thr
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000382051+113612_6440691.0Compositional biasNote=Cys-rich
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000503434+113464_4670690.0Compositional biasNote=Poly-Thr
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000503434+113612_6440690.0Compositional biasNote=Cys-rich
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000504570+113464_4670690.0Compositional biasNote=Poly-Thr
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000504570+113612_6440690.0Compositional biasNote=Cys-rich
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000382051+113464_4670691.0Compositional biasNote=Poly-Thr
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000382051+113612_6440691.0Compositional biasNote=Cys-rich
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000503434+113464_4670690.0Compositional biasNote=Poly-Thr
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000503434+113612_6440690.0Compositional biasNote=Cys-rich
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000504570+113464_4670690.0Compositional biasNote=Poly-Thr
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000504570+113612_6440690.0Compositional biasNote=Cys-rich
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000382051+113464_4670691.0Compositional biasNote=Poly-Thr
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000382051+113612_6440691.0Compositional biasNote=Cys-rich
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000503434+113464_4670690.0Compositional biasNote=Poly-Thr
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000503434+113612_6440690.0Compositional biasNote=Cys-rich
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000504570+113464_4670690.0Compositional biasNote=Poly-Thr
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000504570+113612_6440690.0Compositional biasNote=Cys-rich
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000382051+413122_135126.33333333333333691.0Topological domainExtracellular
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000382051+413157_212126.33333333333333691.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000382051+413234_362126.33333333333333691.0Topological domainExtracellular
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000382051+413384_407126.33333333333333691.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000382051+413429_485126.33333333333333691.0Topological domainExtracellular
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000382051+413507_525126.33333333333333691.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000382051+413547_552126.33333333333333691.0Topological domainExtracellular
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000382051+413574_689126.33333333333333691.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000503434+413122_135125.33333333333333690.0Topological domainExtracellular
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000503434+413157_212125.33333333333333690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000503434+413234_362125.33333333333333690.0Topological domainExtracellular
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000503434+413384_407125.33333333333333690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000503434+413429_485125.33333333333333690.0Topological domainExtracellular
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000503434+413507_525125.33333333333333690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000503434+413547_552125.33333333333333690.0Topological domainExtracellular
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000503434+413574_689125.33333333333333690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000504570+413122_135125.33333333333333690.0Topological domainExtracellular
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000504570+413157_212125.33333333333333690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000504570+413234_362125.33333333333333690.0Topological domainExtracellular
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000504570+413384_407125.33333333333333690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000504570+413429_485125.33333333333333690.0Topological domainExtracellular
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000504570+413507_525125.33333333333333690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000504570+413547_552125.33333333333333690.0Topological domainExtracellular
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000504570+413574_689125.33333333333333690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000382051+413122_135126.33333333333333691.0Topological domainExtracellular
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000382051+413157_212126.33333333333333691.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000382051+413234_362126.33333333333333691.0Topological domainExtracellular
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000382051+413384_407126.33333333333333691.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000382051+413429_485126.33333333333333691.0Topological domainExtracellular
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000382051+413507_525126.33333333333333691.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000382051+413547_552126.33333333333333691.0Topological domainExtracellular
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000382051+413574_689126.33333333333333691.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000503434+413122_135125.33333333333333690.0Topological domainExtracellular
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000503434+413157_212125.33333333333333690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000503434+413234_362125.33333333333333690.0Topological domainExtracellular
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000503434+413384_407125.33333333333333690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000503434+413429_485125.33333333333333690.0Topological domainExtracellular
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000503434+413507_525125.33333333333333690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000503434+413547_552125.33333333333333690.0Topological domainExtracellular
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000503434+413574_689125.33333333333333690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000504570+413122_135125.33333333333333690.0Topological domainExtracellular
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000504570+413157_212125.33333333333333690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000504570+413234_362125.33333333333333690.0Topological domainExtracellular
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000504570+413384_407125.33333333333333690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000504570+413429_485125.33333333333333690.0Topological domainExtracellular
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000504570+413507_525125.33333333333333690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000504570+413547_552125.33333333333333690.0Topological domainExtracellular
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000504570+413574_689125.33333333333333690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000382051+113122_1350691.0Topological domainExtracellular
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000382051+113157_2120691.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000382051+1131_1000691.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000382051+113234_3620691.0Topological domainExtracellular
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000382051+113384_4070691.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000382051+113429_4850691.0Topological domainExtracellular
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000382051+113507_5250691.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000382051+113547_5520691.0Topological domainExtracellular
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000382051+113574_6890691.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000503434+113122_1350690.0Topological domainExtracellular
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000503434+113157_2120690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000503434+1131_1000690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000503434+113234_3620690.0Topological domainExtracellular
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000503434+113384_4070690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000503434+113429_4850690.0Topological domainExtracellular
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000503434+113507_5250690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000503434+113547_5520690.0Topological domainExtracellular
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000503434+113574_6890690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000504570+113122_1350690.0Topological domainExtracellular
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000504570+113157_2120690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000504570+1131_1000690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000504570+113234_3620690.0Topological domainExtracellular
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000504570+113384_4070690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000504570+113429_4850690.0Topological domainExtracellular
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000504570+113507_5250690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000504570+113547_5520690.0Topological domainExtracellular
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000504570+113574_6890690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000382051+113122_1350691.0Topological domainExtracellular
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000382051+113157_2120691.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000382051+1131_1000691.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000382051+113234_3620691.0Topological domainExtracellular
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000382051+113384_4070691.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000382051+113429_4850691.0Topological domainExtracellular
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000382051+113507_5250691.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000382051+113547_5520691.0Topological domainExtracellular
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000382051+113574_6890691.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000503434+113122_1350690.0Topological domainExtracellular
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000503434+113157_2120690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000503434+1131_1000690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000503434+113234_3620690.0Topological domainExtracellular
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000503434+113384_4070690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000503434+113429_4850690.0Topological domainExtracellular
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000503434+113507_5250690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000503434+113547_5520690.0Topological domainExtracellular
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000503434+113574_6890690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000504570+113122_1350690.0Topological domainExtracellular
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000504570+113157_2120690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000504570+1131_1000690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000504570+113234_3620690.0Topological domainExtracellular
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000504570+113384_4070690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000504570+113429_4850690.0Topological domainExtracellular
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000504570+113507_5250690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000504570+113547_5520690.0Topological domainExtracellular
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000504570+113574_6890690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000382051+113122_1350691.0Topological domainExtracellular
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000382051+113157_2120691.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000382051+1131_1000691.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000382051+113234_3620691.0Topological domainExtracellular
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000382051+113384_4070691.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000382051+113429_4850691.0Topological domainExtracellular
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000382051+113507_5250691.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000382051+113547_5520691.0Topological domainExtracellular
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000382051+113574_6890691.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000503434+113122_1350690.0Topological domainExtracellular
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000503434+113157_2120690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000503434+1131_1000690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000503434+113234_3620690.0Topological domainExtracellular
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000503434+113384_4070690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000503434+113429_4850690.0Topological domainExtracellular
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000503434+113507_5250690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000503434+113547_5520690.0Topological domainExtracellular
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000503434+113574_6890690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000504570+113122_1350690.0Topological domainExtracellular
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000504570+113157_2120690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000504570+1131_1000690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000504570+113234_3620690.0Topological domainExtracellular
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000504570+113384_4070690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000504570+113429_4850690.0Topological domainExtracellular
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000504570+113507_5250690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000504570+113547_5520690.0Topological domainExtracellular
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000504570+113574_6890690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000382051+113122_1350691.0Topological domainExtracellular
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000382051+113157_2120691.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000382051+1131_1000691.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000382051+113234_3620691.0Topological domainExtracellular
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000382051+113384_4070691.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000382051+113429_4850691.0Topological domainExtracellular
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000382051+113507_5250691.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000382051+113547_5520691.0Topological domainExtracellular
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000382051+113574_6890691.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000503434+113122_1350690.0Topological domainExtracellular
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000503434+113157_2120690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000503434+1131_1000690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000503434+113234_3620690.0Topological domainExtracellular
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000503434+113384_4070690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000503434+113429_4850690.0Topological domainExtracellular
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000503434+113507_5250690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000503434+113547_5520690.0Topological domainExtracellular
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000503434+113574_6890690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000504570+113122_1350690.0Topological domainExtracellular
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000504570+113157_2120690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000504570+1131_1000690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000504570+113234_3620690.0Topological domainExtracellular
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000504570+113384_4070690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000504570+113429_4850690.0Topological domainExtracellular
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000504570+113507_5250690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000504570+113547_5520690.0Topological domainExtracellular
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000504570+113574_6890690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000382051+113122_1350691.0Topological domainExtracellular
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000382051+113157_2120691.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000382051+1131_1000691.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000382051+113234_3620691.0Topological domainExtracellular
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000382051+113384_4070691.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000382051+113429_4850691.0Topological domainExtracellular
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000382051+113507_5250691.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000382051+113547_5520691.0Topological domainExtracellular
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000382051+113574_6890691.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000503434+113122_1350690.0Topological domainExtracellular
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000503434+113157_2120690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000503434+1131_1000690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000503434+113234_3620690.0Topological domainExtracellular
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000503434+113384_4070690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000503434+113429_4850690.0Topological domainExtracellular
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000503434+113507_5250690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000503434+113547_5520690.0Topological domainExtracellular
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000503434+113574_6890690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000504570+113122_1350690.0Topological domainExtracellular
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000504570+113157_2120690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000504570+1131_1000690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000504570+113234_3620690.0Topological domainExtracellular
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000504570+113384_4070690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000504570+113429_4850690.0Topological domainExtracellular
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000504570+113507_5250690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000504570+113547_5520690.0Topological domainExtracellular
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000504570+113574_6890690.0Topological domainCytoplasmic
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000382051+413136_156126.33333333333333691.0TransmembraneHelical%3B Name%3DM2
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000382051+413213_233126.33333333333333691.0TransmembraneHelical%3B Name%3DM3
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000382051+413363_383126.33333333333333691.0TransmembraneHelical%3B Name%3DM4
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000382051+413408_428126.33333333333333691.0TransmembraneHelical%3B Name%3DM5
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000382051+413486_506126.33333333333333691.0TransmembraneHelical%3B Name%3DM6
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000382051+413526_546126.33333333333333691.0TransmembraneHelical%3B Name%3DM7
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000382051+413553_573126.33333333333333691.0TransmembraneHelical%3B Name%3DM8
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000503434+413136_156125.33333333333333690.0TransmembraneHelical%3B Name%3DM2
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000503434+413213_233125.33333333333333690.0TransmembraneHelical%3B Name%3DM3
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000503434+413363_383125.33333333333333690.0TransmembraneHelical%3B Name%3DM4
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000503434+413408_428125.33333333333333690.0TransmembraneHelical%3B Name%3DM5
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000503434+413486_506125.33333333333333690.0TransmembraneHelical%3B Name%3DM6
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000503434+413526_546125.33333333333333690.0TransmembraneHelical%3B Name%3DM7
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000503434+413553_573125.33333333333333690.0TransmembraneHelical%3B Name%3DM8
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000504570+413136_156125.33333333333333690.0TransmembraneHelical%3B Name%3DM2
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000504570+413213_233125.33333333333333690.0TransmembraneHelical%3B Name%3DM3
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000504570+413363_383125.33333333333333690.0TransmembraneHelical%3B Name%3DM4
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000504570+413408_428125.33333333333333690.0TransmembraneHelical%3B Name%3DM5
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000504570+413486_506125.33333333333333690.0TransmembraneHelical%3B Name%3DM6
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000504570+413526_546125.33333333333333690.0TransmembraneHelical%3B Name%3DM7
HgeneSLC34A2chr4:25665952chr6:117645580ENST00000504570+413553_573125.33333333333333690.0TransmembraneHelical%3B Name%3DM8
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000382051+413136_156126.33333333333333691.0TransmembraneHelical%3B Name%3DM2
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000382051+413213_233126.33333333333333691.0TransmembraneHelical%3B Name%3DM3
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000382051+413363_383126.33333333333333691.0TransmembraneHelical%3B Name%3DM4
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000382051+413408_428126.33333333333333691.0TransmembraneHelical%3B Name%3DM5
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000382051+413486_506126.33333333333333691.0TransmembraneHelical%3B Name%3DM6
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000382051+413526_546126.33333333333333691.0TransmembraneHelical%3B Name%3DM7
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000382051+413553_573126.33333333333333691.0TransmembraneHelical%3B Name%3DM8
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000503434+413136_156125.33333333333333690.0TransmembraneHelical%3B Name%3DM2
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000503434+413213_233125.33333333333333690.0TransmembraneHelical%3B Name%3DM3
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000503434+413363_383125.33333333333333690.0TransmembraneHelical%3B Name%3DM4
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000503434+413408_428125.33333333333333690.0TransmembraneHelical%3B Name%3DM5
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000503434+413486_506125.33333333333333690.0TransmembraneHelical%3B Name%3DM6
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000503434+413526_546125.33333333333333690.0TransmembraneHelical%3B Name%3DM7
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000503434+413553_573125.33333333333333690.0TransmembraneHelical%3B Name%3DM8
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000504570+413136_156125.33333333333333690.0TransmembraneHelical%3B Name%3DM2
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000504570+413213_233125.33333333333333690.0TransmembraneHelical%3B Name%3DM3
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000504570+413363_383125.33333333333333690.0TransmembraneHelical%3B Name%3DM4
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000504570+413408_428125.33333333333333690.0TransmembraneHelical%3B Name%3DM5
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000504570+413486_506125.33333333333333690.0TransmembraneHelical%3B Name%3DM6
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000504570+413526_546125.33333333333333690.0TransmembraneHelical%3B Name%3DM7
HgeneSLC34A2chr4:25665952chr6:117650611ENST00000504570+413553_573125.33333333333333690.0TransmembraneHelical%3B Name%3DM8
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000382051+113101_1210691.0TransmembraneHelical%3B Name%3DM1
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000382051+113136_1560691.0TransmembraneHelical%3B Name%3DM2
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000382051+113213_2330691.0TransmembraneHelical%3B Name%3DM3
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000382051+113363_3830691.0TransmembraneHelical%3B Name%3DM4
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000382051+113408_4280691.0TransmembraneHelical%3B Name%3DM5
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000382051+113486_5060691.0TransmembraneHelical%3B Name%3DM6
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000382051+113526_5460691.0TransmembraneHelical%3B Name%3DM7
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000382051+113553_5730691.0TransmembraneHelical%3B Name%3DM8
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000503434+113101_1210690.0TransmembraneHelical%3B Name%3DM1
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000503434+113136_1560690.0TransmembraneHelical%3B Name%3DM2
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000503434+113213_2330690.0TransmembraneHelical%3B Name%3DM3
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000503434+113363_3830690.0TransmembraneHelical%3B Name%3DM4
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000503434+113408_4280690.0TransmembraneHelical%3B Name%3DM5
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000503434+113486_5060690.0TransmembraneHelical%3B Name%3DM6
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000503434+113526_5460690.0TransmembraneHelical%3B Name%3DM7
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000503434+113553_5730690.0TransmembraneHelical%3B Name%3DM8
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000504570+113101_1210690.0TransmembraneHelical%3B Name%3DM1
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000504570+113136_1560690.0TransmembraneHelical%3B Name%3DM2
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000504570+113213_2330690.0TransmembraneHelical%3B Name%3DM3
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000504570+113363_3830690.0TransmembraneHelical%3B Name%3DM4
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000504570+113408_4280690.0TransmembraneHelical%3B Name%3DM5
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000504570+113486_5060690.0TransmembraneHelical%3B Name%3DM6
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000504570+113526_5460690.0TransmembraneHelical%3B Name%3DM7
HgeneSLC34A2chr4:25678323chr6:117645577ENST00000504570+113553_5730690.0TransmembraneHelical%3B Name%3DM8
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000382051+113101_1210691.0TransmembraneHelical%3B Name%3DM1
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000382051+113136_1560691.0TransmembraneHelical%3B Name%3DM2
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000382051+113213_2330691.0TransmembraneHelical%3B Name%3DM3
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000382051+113363_3830691.0TransmembraneHelical%3B Name%3DM4
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000382051+113408_4280691.0TransmembraneHelical%3B Name%3DM5
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000382051+113486_5060691.0TransmembraneHelical%3B Name%3DM6
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000382051+113526_5460691.0TransmembraneHelical%3B Name%3DM7
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000382051+113553_5730691.0TransmembraneHelical%3B Name%3DM8
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000503434+113101_1210690.0TransmembraneHelical%3B Name%3DM1
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000503434+113136_1560690.0TransmembraneHelical%3B Name%3DM2
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000503434+113213_2330690.0TransmembraneHelical%3B Name%3DM3
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000503434+113363_3830690.0TransmembraneHelical%3B Name%3DM4
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000503434+113408_4280690.0TransmembraneHelical%3B Name%3DM5
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000503434+113486_5060690.0TransmembraneHelical%3B Name%3DM6
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000503434+113526_5460690.0TransmembraneHelical%3B Name%3DM7
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000503434+113553_5730690.0TransmembraneHelical%3B Name%3DM8
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000504570+113101_1210690.0TransmembraneHelical%3B Name%3DM1
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000504570+113136_1560690.0TransmembraneHelical%3B Name%3DM2
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000504570+113213_2330690.0TransmembraneHelical%3B Name%3DM3
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000504570+113363_3830690.0TransmembraneHelical%3B Name%3DM4
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000504570+113408_4280690.0TransmembraneHelical%3B Name%3DM5
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000504570+113486_5060690.0TransmembraneHelical%3B Name%3DM6
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000504570+113526_5460690.0TransmembraneHelical%3B Name%3DM7
HgeneSLC34A2chr4:25678323chr6:117650608ENST00000504570+113553_5730690.0TransmembraneHelical%3B Name%3DM8
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000382051+113101_1210691.0TransmembraneHelical%3B Name%3DM1
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000382051+113136_1560691.0TransmembraneHelical%3B Name%3DM2
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000382051+113213_2330691.0TransmembraneHelical%3B Name%3DM3
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000382051+113363_3830691.0TransmembraneHelical%3B Name%3DM4
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000382051+113408_4280691.0TransmembraneHelical%3B Name%3DM5
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000382051+113486_5060691.0TransmembraneHelical%3B Name%3DM6
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000382051+113526_5460691.0TransmembraneHelical%3B Name%3DM7
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000382051+113553_5730691.0TransmembraneHelical%3B Name%3DM8
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000503434+113101_1210690.0TransmembraneHelical%3B Name%3DM1
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000503434+113136_1560690.0TransmembraneHelical%3B Name%3DM2
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000503434+113213_2330690.0TransmembraneHelical%3B Name%3DM3
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000503434+113363_3830690.0TransmembraneHelical%3B Name%3DM4
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000503434+113408_4280690.0TransmembraneHelical%3B Name%3DM5
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000503434+113486_5060690.0TransmembraneHelical%3B Name%3DM6
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000503434+113526_5460690.0TransmembraneHelical%3B Name%3DM7
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000503434+113553_5730690.0TransmembraneHelical%3B Name%3DM8
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000504570+113101_1210690.0TransmembraneHelical%3B Name%3DM1
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000504570+113136_1560690.0TransmembraneHelical%3B Name%3DM2
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000504570+113213_2330690.0TransmembraneHelical%3B Name%3DM3
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000504570+113363_3830690.0TransmembraneHelical%3B Name%3DM4
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000504570+113408_4280690.0TransmembraneHelical%3B Name%3DM5
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000504570+113486_5060690.0TransmembraneHelical%3B Name%3DM6
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000504570+113526_5460690.0TransmembraneHelical%3B Name%3DM7
HgeneSLC34A2chr4:25678324chr6:117645578ENST00000504570+113553_5730690.0TransmembraneHelical%3B Name%3DM8
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000382051+113101_1210691.0TransmembraneHelical%3B Name%3DM1
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000382051+113136_1560691.0TransmembraneHelical%3B Name%3DM2
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000382051+113213_2330691.0TransmembraneHelical%3B Name%3DM3
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000382051+113363_3830691.0TransmembraneHelical%3B Name%3DM4
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000382051+113408_4280691.0TransmembraneHelical%3B Name%3DM5
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000382051+113486_5060691.0TransmembraneHelical%3B Name%3DM6
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000382051+113526_5460691.0TransmembraneHelical%3B Name%3DM7
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000382051+113553_5730691.0TransmembraneHelical%3B Name%3DM8
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000503434+113101_1210690.0TransmembraneHelical%3B Name%3DM1
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000503434+113136_1560690.0TransmembraneHelical%3B Name%3DM2
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000503434+113213_2330690.0TransmembraneHelical%3B Name%3DM3
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000503434+113363_3830690.0TransmembraneHelical%3B Name%3DM4
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000503434+113408_4280690.0TransmembraneHelical%3B Name%3DM5
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000503434+113486_5060690.0TransmembraneHelical%3B Name%3DM6
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000503434+113526_5460690.0TransmembraneHelical%3B Name%3DM7
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000503434+113553_5730690.0TransmembraneHelical%3B Name%3DM8
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000504570+113101_1210690.0TransmembraneHelical%3B Name%3DM1
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000504570+113136_1560690.0TransmembraneHelical%3B Name%3DM2
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000504570+113213_2330690.0TransmembraneHelical%3B Name%3DM3
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000504570+113363_3830690.0TransmembraneHelical%3B Name%3DM4
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000504570+113408_4280690.0TransmembraneHelical%3B Name%3DM5
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000504570+113486_5060690.0TransmembraneHelical%3B Name%3DM6
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000504570+113526_5460690.0TransmembraneHelical%3B Name%3DM7
HgeneSLC34A2chr4:25678324chr6:117650609ENST00000504570+113553_5730690.0TransmembraneHelical%3B Name%3DM8
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000382051+113101_1210691.0TransmembraneHelical%3B Name%3DM1
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000382051+113136_1560691.0TransmembraneHelical%3B Name%3DM2
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000382051+113213_2330691.0TransmembraneHelical%3B Name%3DM3
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000382051+113363_3830691.0TransmembraneHelical%3B Name%3DM4
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000382051+113408_4280691.0TransmembraneHelical%3B Name%3DM5
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000382051+113486_5060691.0TransmembraneHelical%3B Name%3DM6
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000382051+113526_5460691.0TransmembraneHelical%3B Name%3DM7
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000382051+113553_5730691.0TransmembraneHelical%3B Name%3DM8
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000503434+113101_1210690.0TransmembraneHelical%3B Name%3DM1
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000503434+113136_1560690.0TransmembraneHelical%3B Name%3DM2
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000503434+113213_2330690.0TransmembraneHelical%3B Name%3DM3
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000503434+113363_3830690.0TransmembraneHelical%3B Name%3DM4
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000503434+113408_4280690.0TransmembraneHelical%3B Name%3DM5
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000503434+113486_5060690.0TransmembraneHelical%3B Name%3DM6
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000503434+113526_5460690.0TransmembraneHelical%3B Name%3DM7
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000503434+113553_5730690.0TransmembraneHelical%3B Name%3DM8
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000504570+113101_1210690.0TransmembraneHelical%3B Name%3DM1
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000504570+113136_1560690.0TransmembraneHelical%3B Name%3DM2
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000504570+113213_2330690.0TransmembraneHelical%3B Name%3DM3
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000504570+113363_3830690.0TransmembraneHelical%3B Name%3DM4
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000504570+113408_4280690.0TransmembraneHelical%3B Name%3DM5
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000504570+113486_5060690.0TransmembraneHelical%3B Name%3DM6
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000504570+113526_5460690.0TransmembraneHelical%3B Name%3DM7
HgeneSLC34A2chr4:25678324chr6:117650610ENST00000504570+113553_5730690.0TransmembraneHelical%3B Name%3DM8
TgeneROS1chr4:25665952chr6:117645580ENST000003685083243101_1961852.33333333333332348.0DomainFibronectin type-III 1
TgeneROS1chr4:25665952chr6:117645580ENST0000036850832431043_11501852.33333333333332348.0DomainFibronectin type-III 5
TgeneROS1chr4:25665952chr6:117645580ENST0000036850832431450_15561852.33333333333332348.0DomainFibronectin type-III 6
TgeneROS1chr4:25665952chr6:117645580ENST0000036850832431557_16561852.33333333333332348.0DomainFibronectin type-III 7
TgeneROS1chr4:25665952chr6:117645580ENST0000036850832431658_17511852.33333333333332348.0DomainFibronectin type-III 8
TgeneROS1chr4:25665952chr6:117645580ENST0000036850832431752_18541852.33333333333332348.0DomainFibronectin type-III 9
TgeneROS1chr4:25665952chr6:117645580ENST000003685083243197_2851852.33333333333332348.0DomainFibronectin type-III 2
TgeneROS1chr4:25665952chr6:117645580ENST000003685083243557_6711852.33333333333332348.0DomainFibronectin type-III 3
TgeneROS1chr4:25665952chr6:117645580ENST000003685083243947_10421852.33333333333332348.0DomainFibronectin type-III 4
TgeneROS1chr4:25665952chr6:117650611ENST000003685083043101_1961749.33333333333332348.0DomainFibronectin type-III 1
TgeneROS1chr4:25665952chr6:117650611ENST0000036850830431043_11501749.33333333333332348.0DomainFibronectin type-III 5
TgeneROS1chr4:25665952chr6:117650611ENST0000036850830431450_15561749.33333333333332348.0DomainFibronectin type-III 6
TgeneROS1chr4:25665952chr6:117650611ENST0000036850830431557_16561749.33333333333332348.0DomainFibronectin type-III 7
TgeneROS1chr4:25665952chr6:117650611ENST0000036850830431658_17511749.33333333333332348.0DomainFibronectin type-III 8
TgeneROS1chr4:25665952chr6:117650611ENST000003685083043197_2851749.33333333333332348.0DomainFibronectin type-III 2
TgeneROS1chr4:25665952chr6:117650611ENST000003685083043557_6711749.33333333333332348.0DomainFibronectin type-III 3
TgeneROS1chr4:25665952chr6:117650611ENST000003685083043947_10421749.33333333333332348.0DomainFibronectin type-III 4
TgeneROS1chr4:25678323chr6:117645577ENST000003685083243101_1961852.33333333333332348.0DomainFibronectin type-III 1
TgeneROS1chr4:25678323chr6:117645577ENST0000036850832431043_11501852.33333333333332348.0DomainFibronectin type-III 5
TgeneROS1chr4:25678323chr6:117645577ENST0000036850832431450_15561852.33333333333332348.0DomainFibronectin type-III 6
TgeneROS1chr4:25678323chr6:117645577ENST0000036850832431557_16561852.33333333333332348.0DomainFibronectin type-III 7
TgeneROS1chr4:25678323chr6:117645577ENST0000036850832431658_17511852.33333333333332348.0DomainFibronectin type-III 8
TgeneROS1chr4:25678323chr6:117645577ENST0000036850832431752_18541852.33333333333332348.0DomainFibronectin type-III 9
TgeneROS1chr4:25678323chr6:117645577ENST000003685083243197_2851852.33333333333332348.0DomainFibronectin type-III 2
TgeneROS1chr4:25678323chr6:117645577ENST000003685083243557_6711852.33333333333332348.0DomainFibronectin type-III 3
TgeneROS1chr4:25678323chr6:117645577ENST000003685083243947_10421852.33333333333332348.0DomainFibronectin type-III 4
TgeneROS1chr4:25678323chr6:117650608ENST000003685083043101_1961749.33333333333332348.0DomainFibronectin type-III 1
TgeneROS1chr4:25678323chr6:117650608ENST0000036850830431043_11501749.33333333333332348.0DomainFibronectin type-III 5
TgeneROS1chr4:25678323chr6:117650608ENST0000036850830431450_15561749.33333333333332348.0DomainFibronectin type-III 6
TgeneROS1chr4:25678323chr6:117650608ENST0000036850830431557_16561749.33333333333332348.0DomainFibronectin type-III 7
TgeneROS1chr4:25678323chr6:117650608ENST0000036850830431658_17511749.33333333333332348.0DomainFibronectin type-III 8
TgeneROS1chr4:25678323chr6:117650608ENST000003685083043197_2851749.33333333333332348.0DomainFibronectin type-III 2
TgeneROS1chr4:25678323chr6:117650608ENST000003685083043557_6711749.33333333333332348.0DomainFibronectin type-III 3
TgeneROS1chr4:25678323chr6:117650608ENST000003685083043947_10421749.33333333333332348.0DomainFibronectin type-III 4
TgeneROS1chr4:25678324chr6:117645578ENST000003685083243101_1961852.33333333333332348.0DomainFibronectin type-III 1
TgeneROS1chr4:25678324chr6:117645578ENST0000036850832431043_11501852.33333333333332348.0DomainFibronectin type-III 5
TgeneROS1chr4:25678324chr6:117645578ENST0000036850832431450_15561852.33333333333332348.0DomainFibronectin type-III 6
TgeneROS1chr4:25678324chr6:117645578ENST0000036850832431557_16561852.33333333333332348.0DomainFibronectin type-III 7
TgeneROS1chr4:25678324chr6:117645578ENST0000036850832431658_17511852.33333333333332348.0DomainFibronectin type-III 8
TgeneROS1chr4:25678324chr6:117645578ENST0000036850832431752_18541852.33333333333332348.0DomainFibronectin type-III 9
TgeneROS1chr4:25678324chr6:117645578ENST000003685083243197_2851852.33333333333332348.0DomainFibronectin type-III 2
TgeneROS1chr4:25678324chr6:117645578ENST000003685083243557_6711852.33333333333332348.0DomainFibronectin type-III 3
TgeneROS1chr4:25678324chr6:117645578ENST000003685083243947_10421852.33333333333332348.0DomainFibronectin type-III 4
TgeneROS1chr4:25678324chr6:117650609ENST000003685083043101_1961749.33333333333332348.0DomainFibronectin type-III 1
TgeneROS1chr4:25678324chr6:117650609ENST0000036850830431043_11501749.33333333333332348.0DomainFibronectin type-III 5
TgeneROS1chr4:25678324chr6:117650609ENST0000036850830431450_15561749.33333333333332348.0DomainFibronectin type-III 6
TgeneROS1chr4:25678324chr6:117650609ENST0000036850830431557_16561749.33333333333332348.0DomainFibronectin type-III 7
TgeneROS1chr4:25678324chr6:117650609ENST0000036850830431658_17511749.33333333333332348.0DomainFibronectin type-III 8
TgeneROS1chr4:25678324chr6:117650609ENST000003685083043197_2851749.33333333333332348.0DomainFibronectin type-III 2
TgeneROS1chr4:25678324chr6:117650609ENST000003685083043557_6711749.33333333333332348.0DomainFibronectin type-III 3
TgeneROS1chr4:25678324chr6:117650609ENST000003685083043947_10421749.33333333333332348.0DomainFibronectin type-III 4
TgeneROS1chr4:25678324chr6:117650610ENST000003685083043101_1961749.33333333333332348.0DomainFibronectin type-III 1
TgeneROS1chr4:25678324chr6:117650610ENST0000036850830431043_11501749.33333333333332348.0DomainFibronectin type-III 5
TgeneROS1chr4:25678324chr6:117650610ENST0000036850830431450_15561749.33333333333332348.0DomainFibronectin type-III 6
TgeneROS1chr4:25678324chr6:117650610ENST0000036850830431557_16561749.33333333333332348.0DomainFibronectin type-III 7
TgeneROS1chr4:25678324chr6:117650610ENST0000036850830431658_17511749.33333333333332348.0DomainFibronectin type-III 8
TgeneROS1chr4:25678324chr6:117650610ENST000003685083043197_2851749.33333333333332348.0DomainFibronectin type-III 2
TgeneROS1chr4:25678324chr6:117650610ENST000003685083043557_6711749.33333333333332348.0DomainFibronectin type-III 3
TgeneROS1chr4:25678324chr6:117650610ENST000003685083043947_10421749.33333333333332348.0DomainFibronectin type-III 4
TgeneROS1chr4:25665952chr6:117645580ENST00000368508324328_18591852.33333333333332348.0Topological domainExtracellular
TgeneROS1chr4:25665952chr6:117650611ENST00000368508304328_18591749.33333333333332348.0Topological domainExtracellular
TgeneROS1chr4:25678323chr6:117645577ENST00000368508324328_18591852.33333333333332348.0Topological domainExtracellular
TgeneROS1chr4:25678323chr6:117650608ENST00000368508304328_18591749.33333333333332348.0Topological domainExtracellular
TgeneROS1chr4:25678324chr6:117645578ENST00000368508324328_18591852.33333333333332348.0Topological domainExtracellular
TgeneROS1chr4:25678324chr6:117650609ENST00000368508304328_18591749.33333333333332348.0Topological domainExtracellular
TgeneROS1chr4:25678324chr6:117650610ENST00000368508304328_18591749.33333333333332348.0Topological domainExtracellular


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Fusion Protein Structures

check button PDB and CIF files of the predicted fusion proteins
* Here we show the 3D structure of the fusion proteins using Mol*. AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Model confidence is shown from the pLDDT values per residue. pLDDT corresponds to the model’s prediction of its score on the local Distance Difference Test. It is a measure of local accuracy (from AlphfaFold website). To color code individual residues, we transformed individual PDB files into CIF format.
Fusion protein PDB link (fusion AA seq ID in FusionPDB)HgeneHchrHbpHstrandTgeneTchrTbpTstrandAA seqLen(AA seq)
PDB file (380) >>>380.pdbFusion protein BP residue:
CIF file (380) >>>380.cif		SLC34A2chr425678323+ROS1chr6117650608-
MTFNGSCSSVCTWKSKNLKGIFQFRVVAANNLGFGEYSGISENIILVGDD
FWIPETSFILTIIVGIFLVVTIPLTFVWHRRLKNQKSAKEGVTVLINEDK
ELAELRGLAAGVGLANACYAIHTLPTQEEIENLPAFPREKLTLRLLLGSG
AFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQEKIEFLKEAHLMSKF
NHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYGPLLTLV
DLVDLCVDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFG
LARDIYKNDYYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFGILIWEI
LTLGHQPYPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQ
RPTFHRIQDQLQLFRNFFLNSIYKSRDEANNSGVINESFEGEDGDVICLN
SDDIMPVALMETKNREGLNYMVLATECGQGEEKSEGPLGSQESESCGLRK
543
3D view using mol* of 380 (AA BP:)
PDB file (599) >>>599.pdbFusion protein BP residue: 140
CIF file (599) >>>599.cif		SLC34A2chr425665952+ROS1chr6117650609-
MAAASSPAPAEGALTMAPWPELGDAQPNPDKYLEGAAGQQPTAPDKSKET
NKNNTEAPVTKIELLPSYSTATLIDEPTEVDDPWNLPTLQDSGIKWSERD
TKGKILCFFQGIGRLILLLGFLYFFVCSLDILSSAFQLVGAGVPNKPGIP
KLLEGSKNSIQWEKAEDNGCRITYYILEIRKSTSNNLQNQNLRWKMTFNG
SCSSVCTWKSKNLKGIFQFRVVAANNLGFGEYSGISENIILVGDDFWIPE
TSFILTIIVGIFLVVTIPLTFVWHRRLKNQKSAKEGVTVLINEDKELAEL
RGLAAGVGLANACYAIHTLPTQEEIENLPAFPREKLTLRLLLGSGAFGEV
YEGTAVDILGVGSGEIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFNHPNI
LKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYGPLLTLVDLVDL
CVDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDI
YKNDYYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFGILIWEILTLGH
QPYPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFH
RIQDQLQLFRNFFLNSIYKSRDEANNSGVINESFEGEDGDVICLNSDDIM
PVALMETKNREGLNYMVLATECGQGEEKSEGPLGSQESESCGLRKEEKEP
738
3D view using mol* of 599 (AA BP:140)
PDB file (601) >>>601.pdbFusion protein BP residue: 141
CIF file (601) >>>601.cif		SLC34A2chr425665952+ROS1chr6117650609-
MAAASSPAPAEGALTMAPWPELGDAQPNPDKYLEGAAGQQPTAPDKSKET
NKTDNTEAPVTKIELLPSYSTATLIDEPTEVDDPWNLPTLQDSGIKWSER
DTKGKILCFFQGIGRLILLLGFLYFFVCSLDILSSAFQLVGAGVPNKPGI
PKLLEGSKNSIQWEKAEDNGCRITYYILEIRKSTSNNLQNQNLRWKMTFN
GSCSSVCTWKSKNLKGIFQFRVVAANNLGFGEYSGISENIILVGDDFWIP
ETSFILTIIVGIFLVVTIPLTFVWHRRLKNQKSAKEGVTVLINEDKELAE
LRGLAAGVGLANACYAIHTLPTQEEIENLPAFPREKLTLRLLLGSGAFGE
VYEGTAVDILGVGSGEIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFNHPN
ILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYGPLLTLVDLVD
LCVDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARD
IYKNDYYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFGILIWEILTLG
HQPYPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTF
HRIQDQLQLFRNFFLNSIYKSRDEANNSGVINESFEGEDGDVICLNSDDI
MPVALMETKNREGLNYMVLATECGQGEEKSEGPLGSQESESCGLRKEEKE
739
3D view using mol* of 601 (AA BP:141)
PDB file (602) >>>602.pdbFusion protein BP residue: 141
CIF file (602) >>>602.cif		SLC34A2chr425665952+ROS1chr6117650609-
MGSKARNLCFPSHKWTMAPWPELGDAQPNPDKYLEGAAGQQPTAPDKSKE
TNKNNTEAPVTKIELLPSYSTATLIDEPTEVDDPWNLPTLQDSGIKWSER
DTKGKILCFFQGIGRLILLLGFLYFFVCSLDILSSAFQLVGAGVPNKPGI
PKLLEGSKNSIQWEKAEDNGCRITYYILEIRKSTSNNLQNQNLRWKMTFN
GSCSSVCTWKSKNLKGIFQFRVVAANNLGFGEYSGISENIILVGDDFWIP
ETSFILTIIVGIFLVVTIPLTFVWHRRLKNQKSAKEGVTVLINEDKELAE
LRGLAAGVGLANACYAIHTLPTQEEIENLPAFPREKLTLRLLLGSGAFGE
VYEGTAVDILGVGSGEIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFNHPN
ILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYGPLLTLVDLVD
LCVDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARD
IYKNDYYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFGILIWEILTLG
HQPYPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTF
HRIQDQLQLFRNFFLNSIYKSRDEANNSGVINESFEGEDGDVICLNSDDI
MPVALMETKNREGLNYMVLATECGQGEEKSEGPLGSQESESCGLRKEEKE
739
3D view using mol* of 602 (AA BP:141)


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pLDDT score distribution

check button pLDDT score distribution of the predicted wild-type structures of two partner proteins from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.
SLC34A2_pLDDT.png
all structure
all structure
ROS1_pLDDT.png
all structure
all structure

check button pLDDT score distribution of the predicted fusion protein structures from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.
SLC34A2_ROS1_380_pLDDT.png (AA BP:)
all structure
SLC34A2_ROS1_380_pLDDT_and_active_sites.png (AA BP:)
all structure
SLC34A2_ROS1_380_violinplot.png (AA BP:)
all structure
SLC34A2_ROS1_599_pLDDT.png (AA BP:140)
all structure
SLC34A2_ROS1_599_pLDDT_and_active_sites.png (AA BP:140)
all structure
SLC34A2_ROS1_599_violinplot.png (AA BP:140)
all structure
SLC34A2_ROS1_601_pLDDT.png (AA BP:141)
all structure
SLC34A2_ROS1_601_pLDDT_and_active_sites.png (AA BP:141)
all structure
SLC34A2_ROS1_601_violinplot.png (AA BP:141)
all structure
SLC34A2_ROS1_602_pLDDT.png (AA BP:141)
all structure
SLC34A2_ROS1_602_pLDDT_and_active_sites.png (AA BP:141)
all structure
SLC34A2_ROS1_602_violinplot.png (AA BP:141)
all structure


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Ramachandran Plot of Fusion Protein Structure


check button Ramachandran plot of the torsional angles - phi (φ)and psi (ψ) - of the residues (amino acids) contained in this fusion protein peptide.
Fusion AA seq ID in FusionPDB and their Ramachandran plots
SLC34A2_ROS1_380.png
all structure
SLC34A2_ROS1_599.png
all structure

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Potential Active Site Information


check button The potential binding sites of these fusion proteins were identified using SiteMap, a module of the Schrodinger suite.
Fusion AA seq ID in FusionPDBSite scoreSizeD scoreVolumeExposureEnclosureContactPhobicPhilicBalanceDon/AccResidues
3801.131311.166379.0150.4630.8381.1031.7010.8492.0040.72Chain A: 147,148,155,174,176,193,197,206,222,223,2
24,225,226,227,228,229,236,279,280,282,286,297,298
,299,300,301,302,305,306
5991.1621281.226309.0430.3960.8261.072.2220.6433.4561.841Chain A: 342,343,344,345,350,369,401,417,418,419,4
20,421,422,423,424,427,431,474,475,477,481,492,493
,495,496,497,499,500,501
6011.091321.02253.4770.4240.8331.1350.9681.2890.7510.583Chain A: 343,344,351,353,368,370,402,418,419,420,4
21,422,423,424,425,428,429,432,475,476,478,482,484
,494,497,498,499,502
6021.0931281.042255.1920.4210.8371.121.0541.2270.8590.561Chain A: 343,344,345,346,349,351,353,368,370,402,4
18,419,420,421,422,423,424,425,428,429,432,475,476
,478,482,494,497,498,499,502

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Potentially Interacting Small Molecules through Virtual Screening


check button The FDA-approved small molecule library molecules were subjected to virtual screening using the Glide.
Fusion AA seq ID in FusionPDBZINC IDDrugBank IDDrug nameDocking scoreGlide gscore

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check button Drug information from DrugBank of the top 20 interacting small molecules.
ZINC IDDrugBank IDDrug nameDrug typeSMILESDrug group

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Biochemical Features of Small Molecules


check button ADME (Absorption, Distribution, Metabolism, and Excretion) of drugs using QikProp(v3.9)
ZINC IDmol_MWdipoleSASAFOSAFISAPISAWPSAvolumedonorHBaccptHBIPHuman Oral AbsorptionPercent Human Oral AbsorptionRule Of FiveRule Of Three


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Drug Toxicity Information


check button Toxicity information of individual drugs using eToxPred
ZINC IDSmileSurface AccessibilityToxicity


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Fusion Protein-Protein Interaction


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)
GenePPI interactors
SLC34A2NUDCD1, PCDH10, KRIT1, ENDOD1, ZDHHC18, LMTK2, LINGO2, ATP6V0A1, KIAA1715, ATP11C, ATP6V0A2, SYNGR2, CACNA2D1, SLC30A7, TSPO2, SLC39A7, SLC30A3, TMEM128, C14orf1, AIG1, TEX264, SLC35A1, TMEM42, JAGN1, TUSC5, PNLIPRP1, GUCA2A, LHFPL5, TMEM239, RTP2, PLN, LOC100507537, FXYD6-FXYD2, ZDHHC3, FLOT1, TMEM63B, CMSS1, FLOT2, C12orf43, ATP6V0C, RABL6, QRSL1, ATP6V0D2, MYADM, CD47, CYBRD1, ATP6AP1,


check button Protein-protein interactors based on sequence similarity (STRING)
GeneSTRING network
SLC34A2all structure
ROS1all structure


check button - Retained interactions in fusion protein (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost interactions due to fusion (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs to SLC34A2-ROS1


check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

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Related Diseases to SLC34A2-ROS1


check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID
SLC34A2ROS1Lung AdenocarcinomaMyCancerGenome
SLC34A2ROS1Dedifferentiated LiposarcomaMyCancerGenome
SLC34A2ROS1Breast Invasive Ductal CarcinomaMyCancerGenome
SLC34A2ROS1Anaplastic GangliogliomaMyCancerGenome
SLC34A2ROS1Cancer Of Unknown PrimaryMyCancerGenome

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneSLC34A2C0155912Pulmonary Alveolar Microlithiasis4CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
HgeneSLC34A2C0007131Non-Small Cell Lung Carcinoma2CTD_human
HgeneSLC34A2C0013221Drug toxicity1CTD_human
HgeneSLC34A2C0041755Adverse reaction to drug1CTD_human
TgeneROS1C0007131Non-Small Cell Lung Carcinoma4CTD_human
TgeneROS1C0017638Glioma1CTD_human
TgeneROS1C0025202melanoma1CTD_human
TgeneROS1C0152013Adenocarcinoma of lung (disorder)1CGI;CTD_human
TgeneROS1C0259783mixed gliomas1CTD_human
TgeneROS1C0555198Malignant Glioma1CTD_human