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Center for Computational Systems Medicine level2
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Fusion Gene Summary

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Fusion Gene Sample Information

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Fusion ORF Analysis

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Fusion Amino Acid Sequences

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Fusion Protein Functional Features

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Fusion Protein Structure

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pLDDT scores

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Ramachandran Plot of Fusion Protein Structure

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Fusion Protein-Protein Interaction

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Related drugs with this fusion protein

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Related disease with this fusion protein

Fusion Protein:TRAPPC2-ATP2B3

Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: TRAPPC2-ATP2B3
FusionPDB ID: 93796
FusionGDB2.0 ID: 93796
HgeneTgene
Gene symbol

TRAPPC2

ATP2B3

Gene ID

6399

492

Gene nametrafficking protein particle complex 2ATPase plasma membrane Ca2+ transporting 3
SynonymsMIP2A|SEDL|SEDT|TRAPPC2P1|TRS20|ZNF547L|hYP38334CFAP39|CLA2|OPCA|PMCA3|PMCA3a|SCAX1
Cytomap

Xp22.2

Xq28

Type of geneprotein-codingprotein-coding
Descriptiontrafficking protein particle complex subunit 2sedlinplasma membrane calcium-transporting ATPase 3ATPase, Ca++ transporting, plasma membrane 3cilia and flagella associated protein 39plasma membrane calcium ATPaseplasma membrane calcium pump
Modification date2020031320200313
UniProtAcc.

Q16720

Ensembl transtripts involved in fusion geneENST idsENST00000358231, ENST00000359680, 
ENST00000380579, ENST00000453655, 
ENST00000458511, ENST00000519885, 
ENST00000263519, ENST00000359149, 
ENST00000370181, ENST00000393842, 
ENST00000460549, ENST00000370186, 
ENST00000349466, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score3 X 3 X 3=273 X 5 X 3=45
# samples 45
** MAII scorelog2(4/27*10)=0.567040592723894
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(5/45*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context (manual curation of fusion genes in FusionPDB)

PubMed: TRAPPC2 [Title/Abstract] AND ATP2B3 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)TRAPPC2(13737990)-ATP2B3(152845436), # samples:4
Anticipated loss of major functional domain due to fusion event.TRAPPC2-ATP2B3 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
TRAPPC2-ATP2B3 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
TRAPPC2-ATP2B3 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
TRAPPC2-ATP2B3 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
TRAPPC2-ATP2B3 seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF.
TRAPPC2-ATP2B3 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
TRAPPC2-ATP2B3 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneTRAPPC2

GO:0006355

regulation of transcription, DNA-templated

11134351

TgeneATP2B3

GO:0051480

regulation of cytosolic calcium ion concentration

18029012

TgeneATP2B3

GO:1990034

calcium ion export across plasma membrane

18029012


check buttonFusion gene breakpoints across TRAPPC2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ATP2B3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


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Fusion Gene Sample Information

check buttonFusion gene information from FusionGDB2.0.
check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LGGTCGA-TQ-A8XE-01ATRAPPC2chrX

13737990

-ATP2B3chrX

152845436

+
ChimerDB4LGGTCGA-TQ-A8XE-02ATRAPPC2chrX

13737990

-ATP2B3chrX

152845436

+
ChimerDB4LGGTCGA-TQ-A8XETRAPPC2chrX

13737989

-ATP2B3chrX

152845435

+
ChimerDB4LGGTCGA-TQ-A8XETRAPPC2chrX

13737990

-ATP2B3chrX

152845436

+


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Fusion ORF Analysis


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000453655TRAPPC2chrX13737990-ENST00000349466ATP2B3chrX152845436+977365263685140
ENST00000380579TRAPPC2chrX13737990-ENST00000349466ATP2B3chrX152845436+898286184606140
ENST00000358231TRAPPC2chrX13737990-ENST00000349466ATP2B3chrX152845436+79818654506150
ENST00000458511TRAPPC2chrX13737990-ENST00000349466ATP2B3chrX152845436+91129914619201
ENST00000453655TRAPPC2chrX13737989-ENST00000349466ATP2B3chrX152845435+977365263685140
ENST00000380579TRAPPC2chrX13737989-ENST00000349466ATP2B3chrX152845435+898286184606140
ENST00000358231TRAPPC2chrX13737989-ENST00000349466ATP2B3chrX152845435+79818654506150
ENST00000458511TRAPPC2chrX13737989-ENST00000349466ATP2B3chrX152845435+91129914619201

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000453655ENST00000349466TRAPPC2chrX13737990-ATP2B3chrX152845436+0.0053028660.9946971
ENST00000380579ENST00000349466TRAPPC2chrX13737990-ATP2B3chrX152845436+0.0044235980.9955764
ENST00000358231ENST00000349466TRAPPC2chrX13737990-ATP2B3chrX152845436+0.005289760.9947102
ENST00000458511ENST00000349466TRAPPC2chrX13737990-ATP2B3chrX152845436+0.0021911720.9978089
ENST00000453655ENST00000349466TRAPPC2chrX13737989-ATP2B3chrX152845435+0.0053028660.9946971
ENST00000380579ENST00000349466TRAPPC2chrX13737989-ATP2B3chrX152845435+0.0044235980.9955764
ENST00000358231ENST00000349466TRAPPC2chrX13737989-ATP2B3chrX152845435+0.005289760.9947102
ENST00000458511ENST00000349466TRAPPC2chrX13737989-ATP2B3chrX152845435+0.0021911720.9978089

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Fusion Amino Acid Sequences


check button For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>93796_93796_1_TRAPPC2-ATP2B3_TRAPPC2_chrX_13737989_ENST00000358231_ATP2B3_chrX_152845435_ENST00000349466_length(amino acids)=150AA_BP=44
MSASHCRSHILKTMSGSFYFVIVGHHDNPVFEMEFLPAGKAESKIRVVKAFRSSLYEGLEKPESKTSIHNFMATPEFLINDYTHNIPLID

--------------------------------------------------------------

>93796_93796_2_TRAPPC2-ATP2B3_TRAPPC2_chrX_13737989_ENST00000380579_ATP2B3_chrX_152845435_ENST00000349466_length(amino acids)=140AA_BP=34
MKTMSGSFYFVIVGHHDNPVFEMEFLPAGKAESKIRVVKAFRSSLYEGLEKPESKTSIHNFMATPEFLINDYTHNIPLIDDTDVDENEER

--------------------------------------------------------------

>93796_93796_3_TRAPPC2-ATP2B3_TRAPPC2_chrX_13737989_ENST00000453655_ATP2B3_chrX_152845435_ENST00000349466_length(amino acids)=140AA_BP=34
MKTMSGSFYFVIVGHHDNPVFEMEFLPAGKAESKIRVVKAFRSSLYEGLEKPESKTSIHNFMATPEFLINDYTHNIPLIDDTDVDENEER

--------------------------------------------------------------

>93796_93796_4_TRAPPC2-ATP2B3_TRAPPC2_chrX_13737989_ENST00000458511_ATP2B3_chrX_152845435_ENST00000349466_length(amino acids)=201AA_BP=95
MTLRFRCRPPTAVSPSPPSVTTKDVSRYCQMSSWKQDRSGLRSTELNVLEYQPLCAVRSHILKTMSGSFYFVIVGHHDNPVFEMEFLPAG
KAESKIRVVKAFRSSLYEGLEKPESKTSIHNFMATPEFLINDYTHNIPLIDDTDVDENEERLRAPPPPSPNQNNNAIDSGIYLTTHVTKS

--------------------------------------------------------------

>93796_93796_5_TRAPPC2-ATP2B3_TRAPPC2_chrX_13737990_ENST00000358231_ATP2B3_chrX_152845436_ENST00000349466_length(amino acids)=150AA_BP=44
MSASHCRSHILKTMSGSFYFVIVGHHDNPVFEMEFLPAGKAESKIRVVKAFRSSLYEGLEKPESKTSIHNFMATPEFLINDYTHNIPLID

--------------------------------------------------------------

>93796_93796_6_TRAPPC2-ATP2B3_TRAPPC2_chrX_13737990_ENST00000380579_ATP2B3_chrX_152845436_ENST00000349466_length(amino acids)=140AA_BP=34
MKTMSGSFYFVIVGHHDNPVFEMEFLPAGKAESKIRVVKAFRSSLYEGLEKPESKTSIHNFMATPEFLINDYTHNIPLIDDTDVDENEER

--------------------------------------------------------------

>93796_93796_7_TRAPPC2-ATP2B3_TRAPPC2_chrX_13737990_ENST00000453655_ATP2B3_chrX_152845436_ENST00000349466_length(amino acids)=140AA_BP=34
MKTMSGSFYFVIVGHHDNPVFEMEFLPAGKAESKIRVVKAFRSSLYEGLEKPESKTSIHNFMATPEFLINDYTHNIPLIDDTDVDENEER

--------------------------------------------------------------

>93796_93796_8_TRAPPC2-ATP2B3_TRAPPC2_chrX_13737990_ENST00000458511_ATP2B3_chrX_152845436_ENST00000349466_length(amino acids)=201AA_BP=95
MTLRFRCRPPTAVSPSPPSVTTKDVSRYCQMSSWKQDRSGLRSTELNVLEYQPLCAVRSHILKTMSGSFYFVIVGHHDNPVFEMEFLPAG
KAESKIRVVKAFRSSLYEGLEKPESKTSIHNFMATPEFLINDYTHNIPLIDDTDVDENEERLRAPPPPSPNQNNNAIDSGIYLTTHVTKS

--------------------------------------------------------------

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Fusion Protein Functional Features


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chrX:13737990/chrX:152845436)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.ATP2B3

Q16720

FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

* Minus value of BPloci means that the break pointn is located before the CDS.
- Retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneATP2B3chrX:13737989chrX:152845435ENST0000026351918201174_11791114.01221.0Compositional biasNote=Poly-Pro
TgeneATP2B3chrX:13737989chrX:152845435ENST0000034946619211174_11791114.01221.0Compositional biasNote=Poly-Pro
TgeneATP2B3chrX:13737989chrX:152845435ENST0000035914919211174_11791165.33333333333331174.0Compositional biasNote=Poly-Pro
TgeneATP2B3chrX:13737989chrX:152845435ENST0000037018118201174_11791151.33333333333331160.0Compositional biasNote=Poly-Pro
TgeneATP2B3chrX:13737989chrX:152845435ENST0000037018619211174_11791151.33333333333331160.0Compositional biasNote=Poly-Pro
TgeneATP2B3chrX:13737989chrX:152845435ENST000003938420201174_117901155.0Compositional biasNote=Poly-Pro
TgeneATP2B3chrX:13737989chrX:152845435ENST00000393842020297_30001155.0Compositional biasNote=Poly-Glu
TgeneATP2B3chrX:13737990chrX:152845436ENST0000026351918201174_11791114.01221.0Compositional biasNote=Poly-Pro
TgeneATP2B3chrX:13737990chrX:152845436ENST0000034946619211174_11791114.01221.0Compositional biasNote=Poly-Pro
TgeneATP2B3chrX:13737990chrX:152845436ENST0000035914919211174_11791165.33333333333331174.0Compositional biasNote=Poly-Pro
TgeneATP2B3chrX:13737990chrX:152845436ENST0000037018118201174_11791151.33333333333331160.0Compositional biasNote=Poly-Pro
TgeneATP2B3chrX:13737990chrX:152845436ENST0000037018619211174_11791151.33333333333331160.0Compositional biasNote=Poly-Pro
TgeneATP2B3chrX:13737990chrX:152845436ENST000003938420201174_117901155.0Compositional biasNote=Poly-Pro
TgeneATP2B3chrX:13737990chrX:152845436ENST00000393842020297_30001155.0Compositional biasNote=Poly-Glu
TgeneATP2B3chrX:13737989chrX:152845435ENST0000026351918201115_11241114.01221.0RegionCalmodulin-binding subdomain B
TgeneATP2B3chrX:13737989chrX:152845435ENST0000034946619211115_11241114.01221.0RegionCalmodulin-binding subdomain B
TgeneATP2B3chrX:13737989chrX:152845435ENST000003938420201097_111401155.0RegionCalmodulin-binding subdomain A
TgeneATP2B3chrX:13737989chrX:152845435ENST000003938420201115_112401155.0RegionCalmodulin-binding subdomain B
TgeneATP2B3chrX:13737990chrX:152845436ENST0000026351918201115_11241114.01221.0RegionCalmodulin-binding subdomain B
TgeneATP2B3chrX:13737990chrX:152845436ENST0000034946619211115_11241114.01221.0RegionCalmodulin-binding subdomain B
TgeneATP2B3chrX:13737990chrX:152845436ENST000003938420201097_111401155.0RegionCalmodulin-binding subdomain A
TgeneATP2B3chrX:13737990chrX:152845436ENST000003938420201115_112401155.0RegionCalmodulin-binding subdomain B
TgeneATP2B3chrX:13737989chrX:152845435ENST000003938420201025_103401155.0Topological domainExtracellular
TgeneATP2B3chrX:13737989chrX:152845435ENST000003938420201057_122001155.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737989chrX:152845435ENST00000393842020119_15501155.0Topological domainExtracellular
TgeneATP2B3chrX:13737989chrX:152845435ENST00000393842020177_36401155.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737989chrX:152845435ENST000003938420201_9701155.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737989chrX:152845435ENST00000393842020385_41701155.0Topological domainExtracellular
TgeneATP2B3chrX:13737989chrX:152845435ENST00000393842020436_84901155.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737989chrX:152845435ENST00000393842020870_87901155.0Topological domainExtracellular
TgeneATP2B3chrX:13737989chrX:152845435ENST00000393842020901_92001155.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737989chrX:152845435ENST00000393842020944_96101155.0Topological domainExtracellular
TgeneATP2B3chrX:13737989chrX:152845435ENST00000393842020984_100201155.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737990chrX:152845436ENST000003938420201025_103401155.0Topological domainExtracellular
TgeneATP2B3chrX:13737990chrX:152845436ENST000003938420201057_122001155.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737990chrX:152845436ENST00000393842020119_15501155.0Topological domainExtracellular
TgeneATP2B3chrX:13737990chrX:152845436ENST00000393842020177_36401155.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737990chrX:152845436ENST000003938420201_9701155.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737990chrX:152845436ENST00000393842020385_41701155.0Topological domainExtracellular
TgeneATP2B3chrX:13737990chrX:152845436ENST00000393842020436_84901155.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737990chrX:152845436ENST00000393842020870_87901155.0Topological domainExtracellular
TgeneATP2B3chrX:13737990chrX:152845436ENST00000393842020901_92001155.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737990chrX:152845436ENST00000393842020944_96101155.0Topological domainExtracellular
TgeneATP2B3chrX:13737990chrX:152845436ENST00000393842020984_100201155.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737989chrX:152845435ENST000003938420201003_102401155.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST000003938420201035_105601155.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST00000393842020156_17601155.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST00000393842020365_38401155.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST00000393842020418_43501155.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST00000393842020850_86901155.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST00000393842020880_90001155.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST00000393842020921_94301155.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST00000393842020962_98301155.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST0000039384202098_11801155.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST000003938420201003_102401155.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST000003938420201035_105601155.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST00000393842020156_17601155.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST00000393842020365_38401155.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST00000393842020418_43501155.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST00000393842020850_86901155.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST00000393842020880_90001155.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST00000393842020921_94301155.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST00000393842020962_98301155.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST0000039384202098_11801155.0TransmembraneHelical

- Not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneATP2B3chrX:13737989chrX:152845435ENST000002635191820297_3001114.01221.0Compositional biasNote=Poly-Glu
TgeneATP2B3chrX:13737989chrX:152845435ENST000003494661921297_3001114.01221.0Compositional biasNote=Poly-Glu
TgeneATP2B3chrX:13737989chrX:152845435ENST000003591491921297_3001165.33333333333331174.0Compositional biasNote=Poly-Glu
TgeneATP2B3chrX:13737989chrX:152845435ENST000003701811820297_3001151.33333333333331160.0Compositional biasNote=Poly-Glu
TgeneATP2B3chrX:13737989chrX:152845435ENST000003701861921297_3001151.33333333333331160.0Compositional biasNote=Poly-Glu
TgeneATP2B3chrX:13737990chrX:152845436ENST000002635191820297_3001114.01221.0Compositional biasNote=Poly-Glu
TgeneATP2B3chrX:13737990chrX:152845436ENST000003494661921297_3001114.01221.0Compositional biasNote=Poly-Glu
TgeneATP2B3chrX:13737990chrX:152845436ENST000003591491921297_3001165.33333333333331174.0Compositional biasNote=Poly-Glu
TgeneATP2B3chrX:13737990chrX:152845436ENST000003701811820297_3001151.33333333333331160.0Compositional biasNote=Poly-Glu
TgeneATP2B3chrX:13737990chrX:152845436ENST000003701861921297_3001151.33333333333331160.0Compositional biasNote=Poly-Glu
TgeneATP2B3chrX:13737989chrX:152845435ENST0000026351918201097_11141114.01221.0RegionCalmodulin-binding subdomain A
TgeneATP2B3chrX:13737989chrX:152845435ENST0000034946619211097_11141114.01221.0RegionCalmodulin-binding subdomain A
TgeneATP2B3chrX:13737989chrX:152845435ENST0000035914919211097_11141165.33333333333331174.0RegionCalmodulin-binding subdomain A
TgeneATP2B3chrX:13737989chrX:152845435ENST0000035914919211115_11241165.33333333333331174.0RegionCalmodulin-binding subdomain B
TgeneATP2B3chrX:13737989chrX:152845435ENST0000037018118201097_11141151.33333333333331160.0RegionCalmodulin-binding subdomain A
TgeneATP2B3chrX:13737989chrX:152845435ENST0000037018118201115_11241151.33333333333331160.0RegionCalmodulin-binding subdomain B
TgeneATP2B3chrX:13737989chrX:152845435ENST0000037018619211097_11141151.33333333333331160.0RegionCalmodulin-binding subdomain A
TgeneATP2B3chrX:13737989chrX:152845435ENST0000037018619211115_11241151.33333333333331160.0RegionCalmodulin-binding subdomain B
TgeneATP2B3chrX:13737990chrX:152845436ENST0000026351918201097_11141114.01221.0RegionCalmodulin-binding subdomain A
TgeneATP2B3chrX:13737990chrX:152845436ENST0000034946619211097_11141114.01221.0RegionCalmodulin-binding subdomain A
TgeneATP2B3chrX:13737990chrX:152845436ENST0000035914919211097_11141165.33333333333331174.0RegionCalmodulin-binding subdomain A
TgeneATP2B3chrX:13737990chrX:152845436ENST0000035914919211115_11241165.33333333333331174.0RegionCalmodulin-binding subdomain B
TgeneATP2B3chrX:13737990chrX:152845436ENST0000037018118201097_11141151.33333333333331160.0RegionCalmodulin-binding subdomain A
TgeneATP2B3chrX:13737990chrX:152845436ENST0000037018118201115_11241151.33333333333331160.0RegionCalmodulin-binding subdomain B
TgeneATP2B3chrX:13737990chrX:152845436ENST0000037018619211097_11141151.33333333333331160.0RegionCalmodulin-binding subdomain A
TgeneATP2B3chrX:13737990chrX:152845436ENST0000037018619211115_11241151.33333333333331160.0RegionCalmodulin-binding subdomain B
TgeneATP2B3chrX:13737989chrX:152845435ENST0000026351918201025_10341114.01221.0Topological domainExtracellular
TgeneATP2B3chrX:13737989chrX:152845435ENST0000026351918201057_12201114.01221.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737989chrX:152845435ENST000002635191820119_1551114.01221.0Topological domainExtracellular
TgeneATP2B3chrX:13737989chrX:152845435ENST000002635191820177_3641114.01221.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737989chrX:152845435ENST0000026351918201_971114.01221.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737989chrX:152845435ENST000002635191820385_4171114.01221.0Topological domainExtracellular
TgeneATP2B3chrX:13737989chrX:152845435ENST000002635191820436_8491114.01221.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737989chrX:152845435ENST000002635191820870_8791114.01221.0Topological domainExtracellular
TgeneATP2B3chrX:13737989chrX:152845435ENST000002635191820901_9201114.01221.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737989chrX:152845435ENST000002635191820944_9611114.01221.0Topological domainExtracellular
TgeneATP2B3chrX:13737989chrX:152845435ENST000002635191820984_10021114.01221.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737989chrX:152845435ENST0000034946619211025_10341114.01221.0Topological domainExtracellular
TgeneATP2B3chrX:13737989chrX:152845435ENST0000034946619211057_12201114.01221.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737989chrX:152845435ENST000003494661921119_1551114.01221.0Topological domainExtracellular
TgeneATP2B3chrX:13737989chrX:152845435ENST000003494661921177_3641114.01221.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737989chrX:152845435ENST0000034946619211_971114.01221.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737989chrX:152845435ENST000003494661921385_4171114.01221.0Topological domainExtracellular
TgeneATP2B3chrX:13737989chrX:152845435ENST000003494661921436_8491114.01221.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737989chrX:152845435ENST000003494661921870_8791114.01221.0Topological domainExtracellular
TgeneATP2B3chrX:13737989chrX:152845435ENST000003494661921901_9201114.01221.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737989chrX:152845435ENST000003494661921944_9611114.01221.0Topological domainExtracellular
TgeneATP2B3chrX:13737989chrX:152845435ENST000003494661921984_10021114.01221.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737989chrX:152845435ENST0000035914919211025_10341165.33333333333331174.0Topological domainExtracellular
TgeneATP2B3chrX:13737989chrX:152845435ENST0000035914919211057_12201165.33333333333331174.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737989chrX:152845435ENST000003591491921119_1551165.33333333333331174.0Topological domainExtracellular
TgeneATP2B3chrX:13737989chrX:152845435ENST000003591491921177_3641165.33333333333331174.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737989chrX:152845435ENST0000035914919211_971165.33333333333331174.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737989chrX:152845435ENST000003591491921385_4171165.33333333333331174.0Topological domainExtracellular
TgeneATP2B3chrX:13737989chrX:152845435ENST000003591491921436_8491165.33333333333331174.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737989chrX:152845435ENST000003591491921870_8791165.33333333333331174.0Topological domainExtracellular
TgeneATP2B3chrX:13737989chrX:152845435ENST000003591491921901_9201165.33333333333331174.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737989chrX:152845435ENST000003591491921944_9611165.33333333333331174.0Topological domainExtracellular
TgeneATP2B3chrX:13737989chrX:152845435ENST000003591491921984_10021165.33333333333331174.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737989chrX:152845435ENST0000037018118201025_10341151.33333333333331160.0Topological domainExtracellular
TgeneATP2B3chrX:13737989chrX:152845435ENST0000037018118201057_12201151.33333333333331160.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737989chrX:152845435ENST000003701811820119_1551151.33333333333331160.0Topological domainExtracellular
TgeneATP2B3chrX:13737989chrX:152845435ENST000003701811820177_3641151.33333333333331160.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737989chrX:152845435ENST0000037018118201_971151.33333333333331160.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737989chrX:152845435ENST000003701811820385_4171151.33333333333331160.0Topological domainExtracellular
TgeneATP2B3chrX:13737989chrX:152845435ENST000003701811820436_8491151.33333333333331160.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737989chrX:152845435ENST000003701811820870_8791151.33333333333331160.0Topological domainExtracellular
TgeneATP2B3chrX:13737989chrX:152845435ENST000003701811820901_9201151.33333333333331160.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737989chrX:152845435ENST000003701811820944_9611151.33333333333331160.0Topological domainExtracellular
TgeneATP2B3chrX:13737989chrX:152845435ENST000003701811820984_10021151.33333333333331160.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737989chrX:152845435ENST0000037018619211025_10341151.33333333333331160.0Topological domainExtracellular
TgeneATP2B3chrX:13737989chrX:152845435ENST0000037018619211057_12201151.33333333333331160.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737989chrX:152845435ENST000003701861921119_1551151.33333333333331160.0Topological domainExtracellular
TgeneATP2B3chrX:13737989chrX:152845435ENST000003701861921177_3641151.33333333333331160.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737989chrX:152845435ENST0000037018619211_971151.33333333333331160.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737989chrX:152845435ENST000003701861921385_4171151.33333333333331160.0Topological domainExtracellular
TgeneATP2B3chrX:13737989chrX:152845435ENST000003701861921436_8491151.33333333333331160.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737989chrX:152845435ENST000003701861921870_8791151.33333333333331160.0Topological domainExtracellular
TgeneATP2B3chrX:13737989chrX:152845435ENST000003701861921901_9201151.33333333333331160.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737989chrX:152845435ENST000003701861921944_9611151.33333333333331160.0Topological domainExtracellular
TgeneATP2B3chrX:13737989chrX:152845435ENST000003701861921984_10021151.33333333333331160.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737990chrX:152845436ENST0000026351918201025_10341114.01221.0Topological domainExtracellular
TgeneATP2B3chrX:13737990chrX:152845436ENST0000026351918201057_12201114.01221.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737990chrX:152845436ENST000002635191820119_1551114.01221.0Topological domainExtracellular
TgeneATP2B3chrX:13737990chrX:152845436ENST000002635191820177_3641114.01221.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737990chrX:152845436ENST0000026351918201_971114.01221.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737990chrX:152845436ENST000002635191820385_4171114.01221.0Topological domainExtracellular
TgeneATP2B3chrX:13737990chrX:152845436ENST000002635191820436_8491114.01221.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737990chrX:152845436ENST000002635191820870_8791114.01221.0Topological domainExtracellular
TgeneATP2B3chrX:13737990chrX:152845436ENST000002635191820901_9201114.01221.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737990chrX:152845436ENST000002635191820944_9611114.01221.0Topological domainExtracellular
TgeneATP2B3chrX:13737990chrX:152845436ENST000002635191820984_10021114.01221.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737990chrX:152845436ENST0000034946619211025_10341114.01221.0Topological domainExtracellular
TgeneATP2B3chrX:13737990chrX:152845436ENST0000034946619211057_12201114.01221.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737990chrX:152845436ENST000003494661921119_1551114.01221.0Topological domainExtracellular
TgeneATP2B3chrX:13737990chrX:152845436ENST000003494661921177_3641114.01221.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737990chrX:152845436ENST0000034946619211_971114.01221.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737990chrX:152845436ENST000003494661921385_4171114.01221.0Topological domainExtracellular
TgeneATP2B3chrX:13737990chrX:152845436ENST000003494661921436_8491114.01221.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737990chrX:152845436ENST000003494661921870_8791114.01221.0Topological domainExtracellular
TgeneATP2B3chrX:13737990chrX:152845436ENST000003494661921901_9201114.01221.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737990chrX:152845436ENST000003494661921944_9611114.01221.0Topological domainExtracellular
TgeneATP2B3chrX:13737990chrX:152845436ENST000003494661921984_10021114.01221.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737990chrX:152845436ENST0000035914919211025_10341165.33333333333331174.0Topological domainExtracellular
TgeneATP2B3chrX:13737990chrX:152845436ENST0000035914919211057_12201165.33333333333331174.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737990chrX:152845436ENST000003591491921119_1551165.33333333333331174.0Topological domainExtracellular
TgeneATP2B3chrX:13737990chrX:152845436ENST000003591491921177_3641165.33333333333331174.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737990chrX:152845436ENST0000035914919211_971165.33333333333331174.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737990chrX:152845436ENST000003591491921385_4171165.33333333333331174.0Topological domainExtracellular
TgeneATP2B3chrX:13737990chrX:152845436ENST000003591491921436_8491165.33333333333331174.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737990chrX:152845436ENST000003591491921870_8791165.33333333333331174.0Topological domainExtracellular
TgeneATP2B3chrX:13737990chrX:152845436ENST000003591491921901_9201165.33333333333331174.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737990chrX:152845436ENST000003591491921944_9611165.33333333333331174.0Topological domainExtracellular
TgeneATP2B3chrX:13737990chrX:152845436ENST000003591491921984_10021165.33333333333331174.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737990chrX:152845436ENST0000037018118201025_10341151.33333333333331160.0Topological domainExtracellular
TgeneATP2B3chrX:13737990chrX:152845436ENST0000037018118201057_12201151.33333333333331160.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737990chrX:152845436ENST000003701811820119_1551151.33333333333331160.0Topological domainExtracellular
TgeneATP2B3chrX:13737990chrX:152845436ENST000003701811820177_3641151.33333333333331160.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737990chrX:152845436ENST0000037018118201_971151.33333333333331160.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737990chrX:152845436ENST000003701811820385_4171151.33333333333331160.0Topological domainExtracellular
TgeneATP2B3chrX:13737990chrX:152845436ENST000003701811820436_8491151.33333333333331160.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737990chrX:152845436ENST000003701811820870_8791151.33333333333331160.0Topological domainExtracellular
TgeneATP2B3chrX:13737990chrX:152845436ENST000003701811820901_9201151.33333333333331160.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737990chrX:152845436ENST000003701811820944_9611151.33333333333331160.0Topological domainExtracellular
TgeneATP2B3chrX:13737990chrX:152845436ENST000003701811820984_10021151.33333333333331160.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737990chrX:152845436ENST0000037018619211025_10341151.33333333333331160.0Topological domainExtracellular
TgeneATP2B3chrX:13737990chrX:152845436ENST0000037018619211057_12201151.33333333333331160.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737990chrX:152845436ENST000003701861921119_1551151.33333333333331160.0Topological domainExtracellular
TgeneATP2B3chrX:13737990chrX:152845436ENST000003701861921177_3641151.33333333333331160.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737990chrX:152845436ENST0000037018619211_971151.33333333333331160.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737990chrX:152845436ENST000003701861921385_4171151.33333333333331160.0Topological domainExtracellular
TgeneATP2B3chrX:13737990chrX:152845436ENST000003701861921436_8491151.33333333333331160.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737990chrX:152845436ENST000003701861921870_8791151.33333333333331160.0Topological domainExtracellular
TgeneATP2B3chrX:13737990chrX:152845436ENST000003701861921901_9201151.33333333333331160.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737990chrX:152845436ENST000003701861921944_9611151.33333333333331160.0Topological domainExtracellular
TgeneATP2B3chrX:13737990chrX:152845436ENST000003701861921984_10021151.33333333333331160.0Topological domainCytoplasmic
TgeneATP2B3chrX:13737989chrX:152845435ENST0000026351918201003_10241114.01221.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST0000026351918201035_10561114.01221.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST000002635191820156_1761114.01221.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST000002635191820365_3841114.01221.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST000002635191820418_4351114.01221.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST000002635191820850_8691114.01221.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST000002635191820880_9001114.01221.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST000002635191820921_9431114.01221.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST000002635191820962_9831114.01221.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST00000263519182098_1181114.01221.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST0000034946619211003_10241114.01221.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST0000034946619211035_10561114.01221.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST000003494661921156_1761114.01221.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST000003494661921365_3841114.01221.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST000003494661921418_4351114.01221.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST000003494661921850_8691114.01221.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST000003494661921880_9001114.01221.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST000003494661921921_9431114.01221.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST000003494661921962_9831114.01221.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST00000349466192198_1181114.01221.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST0000035914919211003_10241165.33333333333331174.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST0000035914919211035_10561165.33333333333331174.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST000003591491921156_1761165.33333333333331174.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST000003591491921365_3841165.33333333333331174.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST000003591491921418_4351165.33333333333331174.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST000003591491921850_8691165.33333333333331174.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST000003591491921880_9001165.33333333333331174.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST000003591491921921_9431165.33333333333331174.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST000003591491921962_9831165.33333333333331174.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST00000359149192198_1181165.33333333333331174.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST0000037018118201003_10241151.33333333333331160.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST0000037018118201035_10561151.33333333333331160.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST000003701811820156_1761151.33333333333331160.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST000003701811820365_3841151.33333333333331160.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST000003701811820418_4351151.33333333333331160.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST000003701811820850_8691151.33333333333331160.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST000003701811820880_9001151.33333333333331160.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST000003701811820921_9431151.33333333333331160.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST000003701811820962_9831151.33333333333331160.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST00000370181182098_1181151.33333333333331160.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST0000037018619211003_10241151.33333333333331160.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST0000037018619211035_10561151.33333333333331160.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST000003701861921156_1761151.33333333333331160.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST000003701861921365_3841151.33333333333331160.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST000003701861921418_4351151.33333333333331160.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST000003701861921850_8691151.33333333333331160.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST000003701861921880_9001151.33333333333331160.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST000003701861921921_9431151.33333333333331160.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST000003701861921962_9831151.33333333333331160.0TransmembraneHelical
TgeneATP2B3chrX:13737989chrX:152845435ENST00000370186192198_1181151.33333333333331160.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST0000026351918201003_10241114.01221.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST0000026351918201035_10561114.01221.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST000002635191820156_1761114.01221.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST000002635191820365_3841114.01221.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST000002635191820418_4351114.01221.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST000002635191820850_8691114.01221.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST000002635191820880_9001114.01221.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST000002635191820921_9431114.01221.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST000002635191820962_9831114.01221.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST00000263519182098_1181114.01221.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST0000034946619211003_10241114.01221.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST0000034946619211035_10561114.01221.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST000003494661921156_1761114.01221.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST000003494661921365_3841114.01221.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST000003494661921418_4351114.01221.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST000003494661921850_8691114.01221.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST000003494661921880_9001114.01221.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST000003494661921921_9431114.01221.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST000003494661921962_9831114.01221.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST00000349466192198_1181114.01221.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST0000035914919211003_10241165.33333333333331174.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST0000035914919211035_10561165.33333333333331174.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST000003591491921156_1761165.33333333333331174.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST000003591491921365_3841165.33333333333331174.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST000003591491921418_4351165.33333333333331174.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST000003591491921850_8691165.33333333333331174.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST000003591491921880_9001165.33333333333331174.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST000003591491921921_9431165.33333333333331174.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST000003591491921962_9831165.33333333333331174.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST00000359149192198_1181165.33333333333331174.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST0000037018118201003_10241151.33333333333331160.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST0000037018118201035_10561151.33333333333331160.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST000003701811820156_1761151.33333333333331160.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST000003701811820365_3841151.33333333333331160.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST000003701811820418_4351151.33333333333331160.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST000003701811820850_8691151.33333333333331160.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST000003701811820880_9001151.33333333333331160.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST000003701811820921_9431151.33333333333331160.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST000003701811820962_9831151.33333333333331160.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST00000370181182098_1181151.33333333333331160.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST0000037018619211003_10241151.33333333333331160.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST0000037018619211035_10561151.33333333333331160.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST000003701861921156_1761151.33333333333331160.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST000003701861921365_3841151.33333333333331160.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST000003701861921418_4351151.33333333333331160.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST000003701861921850_8691151.33333333333331160.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST000003701861921880_9001151.33333333333331160.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST000003701861921921_9431151.33333333333331160.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST000003701861921962_9831151.33333333333331160.0TransmembraneHelical
TgeneATP2B3chrX:13737990chrX:152845436ENST00000370186192198_1181151.33333333333331160.0TransmembraneHelical


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Fusion Protein Structures

check button PDB and CIF files of the predicted fusion proteins
* Here we show the 3D structure of the fusion proteins using Mol*. AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Model confidence is shown from the pLDDT values per residue. pLDDT corresponds to the model’s prediction of its score on the local Distance Difference Test. It is a measure of local accuracy (from AlphfaFold website). To color code individual residues, we transformed individual PDB files into CIF format.
Fusion protein PDB link (fusion AA seq ID in FusionPDB)HgeneHchrHbpHstrandTgeneTchrTbpTstrandAA seqLen(AA seq)
PDB file >>>271_TRAPPC2_13737990_ATP2B3_152845436_ranked_0.pdbTRAPPC21373798913737990ENST00000349466ATP2B3chrX152845436+
MTLRFRCRPPTAVSPSPPSVTTKDVSRYCQMSSWKQDRSGLRSTELNVLEYQPLCAVRSHILKTMSGSFYFVIVGHHDNPVFEMEFLPAG
KAESKIRVVKAFRSSLYEGLEKPESKTSIHNFMATPEFLINDYTHNIPLIDDTDVDENEERLRAPPPPSPNQNNNAIDSGIYLTTHVTKS
201


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pLDDT score distribution

check button pLDDT score distribution of the predicted wild-type structures of two partner proteins from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.
TRAPPC2_pLDDT.png
all structure
all structure
ATP2B3_pLDDT.png
all structure
all structure

check button pLDDT score distribution of the predicted fusion protein structures from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.
all structure


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Ramachandran Plot of Fusion Protein Structure


check button Ramachandran plot of the torsional angles - phi (φ)and psi (ψ) - of the residues (amino acids) contained in this fusion protein peptide.
Fusion AA seq ID in FusionPDB and their Ramachandran plots

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Fusion Protein-Protein Interaction


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)
GenePPI interactors


check button Protein-protein interactors based on sequence similarity (STRING)
GeneSTRING network
TRAPPC2
ATP2B3


check button - Retained interactions in fusion protein (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost interactions due to fusion (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs to TRAPPC2-ATP2B3


check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

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Related Diseases to TRAPPC2-ATP2B3


check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource