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Center for Computational Systems Medicine level2
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Fusion Gene Summary

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Fusion Gene Sample Information

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Fusion ORF Analysis

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Fusion Amino Acid Sequences

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Fusion Protein Functional Features

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Fusion Protein Structure

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pLDDT scores

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Ramachandran Plot of Fusion Protein Structure

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Fusion Protein-Protein Interaction

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Related drugs with this fusion protein

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Related disease with this fusion protein

Fusion Protein:CAMKK2-KDM2B

Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: CAMKK2-KDM2B
FusionPDB ID: 12706
FusionGDB2.0 ID: 12706
HgeneTgene
Gene symbol

CAMKK2

KDM2B

Gene ID

10645

84678

Gene namecalcium/calmodulin dependent protein kinase kinase 2lysine demethylase 2B
SynonymsCAMKK|CAMKKBCXXC2|FBXL10|Fbl10|JHDM1B|PCCX2
Cytomap

12q24.31

12q24.31

Type of geneprotein-codingprotein-coding
Descriptioncalcium/calmodulin-dependent protein kinase kinase 2CAMKK beta proteincaM-KK 2caM-KK betacaM-kinase kinase 2caM-kinase kinase betacalcium/calmodulin-dependent protein kinase betacalcium/calmodulin-dependent protein kinase kinase 2, betalysine-specific demethylase 2BCXXC-type zinc finger protein 2F-box and leucine-rich repeat protein 10F-box protein FBL10F-box/LRR-repeat protein 10JEMMA (Jumonji domain, EMSY-interactor, methyltransferase motif) protein[Histone-H3]-lysine-36 demethy
Modification date2020031320200313
UniProtAcc

Q96RR4

Q8NHM5

Ensembl transtripts involved in fusion geneENST idsENST00000324774, ENST00000337174, 
ENST00000347034, ENST00000392473, 
ENST00000392474, ENST00000402834, 
ENST00000404169, ENST00000412367, 
ENST00000446440, ENST00000538733, 
ENST00000545538, ENST00000535524, 
ENST00000377071, ENST00000536437, 
ENST00000538046, ENST00000542973, 
ENST00000377069, ENST00000543852, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score12 X 17 X 9=18368 X 13 X 8=832
# samples 2218
** MAII scorelog2(22/1836*10)=-3.06099062988915
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(18/832*10)=-2.20858662181142
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)

PubMed: CAMKK2 [Title/Abstract] AND KDM2B [Title/Abstract] AND fusion [Title/Abstract]

Mutational Analysis of Gene Fusions Predicts Novel MHC Class I–Restricted T-Cell Epitopes and Immune Signatures in a Subset of Prostate Cancer (pmid: 28954787)
Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)CAMKK2(121708701)-KDM2B(121891147), # samples:5
Anticipated loss of major functional domain due to fusion event.CAMKK2-KDM2B seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CAMKK2-KDM2B seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CAMKK2-KDM2B seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
CAMKK2-KDM2B seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
CAMKK2-KDM2B seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
CAMKK2-KDM2B seems lost the major protein functional domain in Hgene partner, which is a kinase due to the frame-shifted ORF.
CAMKK2-KDM2B seems lost the major protein functional domain in Tgene partner, which is a epigenetic factor due to the frame-shifted ORF.
CAMKK2-KDM2B seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
CAMKK2-KDM2B seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
CAMKK2-KDM2B seems lost the major protein functional domain in Tgene partner, which is a transcription factor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCAMKK2

GO:0006468

protein phosphorylation

11395482

HgeneCAMKK2

GO:0046777

protein autophosphorylation

11395482

TgeneKDM2B

GO:0035518

histone H2A monoubiquitination

16943429

TgeneKDM2B

GO:0070544

histone H3-K36 demethylation

26237645


check buttonFusion gene breakpoints across CAMKK2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across KDM2B (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


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Fusion Gene Sample Information

check buttonFusion gene information from FusionGDB2.0.
check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4ESCATCGA-LN-A4A2-01ACAMKK2chr12

121706441

-KDM2Bchr12

121891147

-
ChimerDB4LAMLTCGA-AB-2817-03ACAMKK2chr12

121682943

-KDM2Bchr12

121891147

-
ChimerDB4PRADTCGA-EJ-5509-01ACAMKK2chr12

121711859

-KDM2Bchr12

121932468

-
ChimerDB4PRADTCGA-EJ-5509CAMKK2chr12

121708701

-KDM2Bchr12

121891147

-
ChimerDB4PRADTCGA-EJ-5509CAMKK2chr12

121711859

-KDM2Bchr12

121932468

-
ChimerDB4PRADTCGA-EJ-A46B-01ACAMKK2chr12

121707331

-KDM2Bchr12

121932468

-
ChimerDB4PRADTCGA-EJ-A46BCAMKK2chr12

121707331

-KDM2Bchr12

121932468

-
ChimerDB4PRADTCGA-EJ-A65J-01ACAMKK2chr12

121708701

-KDM2Bchr12

121891147

-
ChimerDB4PRADTCGA-EJ-A65JCAMKK2chr12

121708701

-KDM2Bchr12

121891147

-
ChimerDB4PRADTCGA-EJ-A65JCAMKK2chr12

121735341

-KDM2Bchr12

121951205

-
ChimerDB4PRADTCGA-EJ-A65JCAMKK2chr12

121735342

-KDM2Bchr12

121891147

-
ChimerDB4PRADTCGA-EJ-A65JCAMKK2chr12

121735342

-KDM2Bchr12

121951205

-
ChimerDB4PRADTCGA-G9-6333-01ACAMKK2chr12

121675497

-KDM2Bchr12

121954666

-
ChimerDB4PRADTCGA-G9-6333-01ACAMKK2chr12

121708701

-KDM2Bchr12

121891147

-
ChimerDB4UCECTCGA-B5-A3S1-01ACAMKK2chr12

121734441

-KDM2Bchr12

121868272

-


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Fusion ORF Analysis


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000412367CAMKK2chr12121682943-ENST00000377069KDM2Bchr12121891147-4837166116913817708
ENST00000404169CAMKK2chr12121682943-ENST00000377069KDM2Bchr12121891147-4904172817583884708
ENST00000402834CAMKK2chr12121682943-ENST00000377069KDM2Bchr12121891147-4861168517153841708
ENST00000392474CAMKK2chr12121711859-ENST00000377069KDM2Bchr12121932468-373947652719904
ENST00000538733CAMKK2chr12121711859-ENST00000377069KDM2Bchr12121932468-431210493323292986
ENST00000337174CAMKK2chr12121711859-ENST00000377069KDM2Bchr12121932468-431210493323292986
ENST00000347034CAMKK2chr12121711859-ENST00000377069KDM2Bchr12121932468-431210493323292986
ENST00000324774CAMKK2chr12121711859-ENST00000377069KDM2Bchr12121932468-456313005833543986
ENST00000446440CAMKK2chr12121711859-ENST00000377069KDM2Bchr12121932468-431210493323292986
ENST00000392473CAMKK2chr12121711859-ENST00000377069KDM2Bchr12121932468-456313005833543986
ENST00000392474CAMKK2chr12121707331-ENST00000377069KDM2Bchr12121932468-384157852821938
ENST00000538733CAMKK2chr12121707331-ENST00000377069KDM2Bchr12121932468-4414115133233941020
ENST00000337174CAMKK2chr12121707331-ENST00000377069KDM2Bchr12121932468-4414115133233941020
ENST00000347034CAMKK2chr12121707331-ENST00000377069KDM2Bchr12121932468-4414115133233941020
ENST00000324774CAMKK2chr12121707331-ENST00000377069KDM2Bchr12121932468-4665140258336451020
ENST00000446440CAMKK2chr12121707331-ENST00000377069KDM2Bchr12121932468-4414115133233941020
ENST00000392473CAMKK2chr12121707331-ENST00000377069KDM2Bchr12121932468-4665140258336451020
ENST00000392474CAMKK2chr12121708701-ENST00000377069KDM2Bchr12121891147-370052452680891
ENST00000538733CAMKK2chr12121708701-ENST00000377069KDM2Bchr12121891147-427310973323253973
ENST00000337174CAMKK2chr12121708701-ENST00000377069KDM2Bchr12121891147-427310973323253973
ENST00000347034CAMKK2chr12121708701-ENST00000377069KDM2Bchr12121891147-427310973323253973
ENST00000324774CAMKK2chr12121708701-ENST00000377069KDM2Bchr12121891147-452413485833504973
ENST00000446440CAMKK2chr12121708701-ENST00000377069KDM2Bchr12121891147-427310973323253973
ENST00000392473CAMKK2chr12121708701-ENST00000377069KDM2Bchr12121891147-452413485833504973

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000412367ENST00000377069CAMKK2chr12121682943-KDM2Bchr12121891147-0.0316785240.9683215
ENST00000404169ENST00000377069CAMKK2chr12121682943-KDM2Bchr12121891147-0.032758210.9672418
ENST00000402834ENST00000377069CAMKK2chr12121682943-KDM2Bchr12121891147-0.0332602750.96673965
ENST00000392474ENST00000377069CAMKK2chr12121711859-KDM2Bchr12121932468-0.0079121930.9920878
ENST00000538733ENST00000377069CAMKK2chr12121711859-KDM2Bchr12121932468-0.0064153030.9935847
ENST00000337174ENST00000377069CAMKK2chr12121711859-KDM2Bchr12121932468-0.0064153030.9935847
ENST00000347034ENST00000377069CAMKK2chr12121711859-KDM2Bchr12121932468-0.0064153030.9935847
ENST00000324774ENST00000377069CAMKK2chr12121711859-KDM2Bchr12121932468-0.0058061830.99419385
ENST00000446440ENST00000377069CAMKK2chr12121711859-KDM2Bchr12121932468-0.0064153030.9935847
ENST00000392473ENST00000377069CAMKK2chr12121711859-KDM2Bchr12121932468-0.0058061830.99419385
ENST00000392474ENST00000377069CAMKK2chr12121707331-KDM2Bchr12121932468-0.0048818880.99511814
ENST00000538733ENST00000377069CAMKK2chr12121707331-KDM2Bchr12121932468-0.0040613060.99593866
ENST00000337174ENST00000377069CAMKK2chr12121707331-KDM2Bchr12121932468-0.0040613060.99593866
ENST00000347034ENST00000377069CAMKK2chr12121707331-KDM2Bchr12121932468-0.0040613060.99593866
ENST00000324774ENST00000377069CAMKK2chr12121707331-KDM2Bchr12121932468-0.0047859940.995214
ENST00000446440ENST00000377069CAMKK2chr12121707331-KDM2Bchr12121932468-0.0040613060.99593866
ENST00000392473ENST00000377069CAMKK2chr12121707331-KDM2Bchr12121932468-0.0047859940.995214
ENST00000392474ENST00000377069CAMKK2chr12121708701-KDM2Bchr12121891147-0.0086438010.99135613
ENST00000538733ENST00000377069CAMKK2chr12121708701-KDM2Bchr12121891147-0.0070277430.99297225
ENST00000337174ENST00000377069CAMKK2chr12121708701-KDM2Bchr12121891147-0.0070277430.99297225
ENST00000347034ENST00000377069CAMKK2chr12121708701-KDM2Bchr12121891147-0.0070277430.99297225
ENST00000324774ENST00000377069CAMKK2chr12121708701-KDM2Bchr12121891147-0.0063183120.99368167
ENST00000446440ENST00000377069CAMKK2chr12121708701-KDM2Bchr12121891147-0.0070277430.99297225
ENST00000392473ENST00000377069CAMKK2chr12121708701-KDM2Bchr12121891147-0.0063183120.99368167

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Fusion Amino Acid Sequences


check button For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>12706_12706_1_CAMKK2-KDM2B_CAMKK2_chr12_121682943_ENST00000402834_KDM2B_chr12_121891147_ENST00000377069_length(amino acids)=708AA_BP=
MGPASAVKLAANRTTAGARRRRTRCRKCEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQCIAPVLPHTAVCLVCGEAGKEDTVEEEE
GKFNLMLMECSICNEIIHPGCLKIKESEGVVNDELPNCWECPKCNHAGKTGKQKRGPGFKYASNLPGSLLKEQKMNRDNKEGQEPAKRRS
ECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEKPQELSGRKRLKPGKEDKLFRKKRRSWKNAEDRMALANKPLRRFKQEPEDE
LPEAPPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKELSRELSKELNHEIQRTENSLANENQQPIKSEPESEGEEPKR
PPGICERPHRFSKGLNGTPRELRHQLGPSLRSPPRVISRPPPSVSPPKCIQMERHVIRPPPISPPPDSLPLDDGAAHVMHREVWMAVFSY
LSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIRRQPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSA
LCSSSCPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLDITDASLRLIIRHMPLLSKLHLSYCNHVTDQSI

--------------------------------------------------------------

>12706_12706_2_CAMKK2-KDM2B_CAMKK2_chr12_121682943_ENST00000404169_KDM2B_chr12_121891147_ENST00000377069_length(amino acids)=708AA_BP=
MGPASAVKLAANRTTAGARRRRTRCRKCEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQCIAPVLPHTAVCLVCGEAGKEDTVEEEE
GKFNLMLMECSICNEIIHPGCLKIKESEGVVNDELPNCWECPKCNHAGKTGKQKRGPGFKYASNLPGSLLKEQKMNRDNKEGQEPAKRRS
ECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEKPQELSGRKRLKPGKEDKLFRKKRRSWKNAEDRMALANKPLRRFKQEPEDE
LPEAPPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKELSRELSKELNHEIQRTENSLANENQQPIKSEPESEGEEPKR
PPGICERPHRFSKGLNGTPRELRHQLGPSLRSPPRVISRPPPSVSPPKCIQMERHVIRPPPISPPPDSLPLDDGAAHVMHREVWMAVFSY
LSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIRRQPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSA
LCSSSCPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLDITDASLRLIIRHMPLLSKLHLSYCNHVTDQSI

--------------------------------------------------------------

>12706_12706_3_CAMKK2-KDM2B_CAMKK2_chr12_121682943_ENST00000412367_KDM2B_chr12_121891147_ENST00000377069_length(amino acids)=708AA_BP=
MGPASAVKLAANRTTAGARRRRTRCRKCEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQCIAPVLPHTAVCLVCGEAGKEDTVEEEE
GKFNLMLMECSICNEIIHPGCLKIKESEGVVNDELPNCWECPKCNHAGKTGKQKRGPGFKYASNLPGSLLKEQKMNRDNKEGQEPAKRRS
ECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEKPQELSGRKRLKPGKEDKLFRKKRRSWKNAEDRMALANKPLRRFKQEPEDE
LPEAPPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKELSRELSKELNHEIQRTENSLANENQQPIKSEPESEGEEPKR
PPGICERPHRFSKGLNGTPRELRHQLGPSLRSPPRVISRPPPSVSPPKCIQMERHVIRPPPISPPPDSLPLDDGAAHVMHREVWMAVFSY
LSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIRRQPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSA
LCSSSCPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLDITDASLRLIIRHMPLLSKLHLSYCNHVTDQSI

--------------------------------------------------------------

>12706_12706_4_CAMKK2-KDM2B_CAMKK2_chr12_121707331_ENST00000324774_KDM2B_chr12_121932468_ENST00000377069_length(amino acids)=1020AA_BP=273
MEVDSPVNSIPFWLFGRVSETSPGSLDPVGRFREPSRSSFLLFPAQCCYPAGGSNAHLRLQQSGSAAGWECPSVLDEAGACTMSSCVSSQ
PSSNRAAPQDELGGRGSSSSESQKPCEALRGLSSLSIHLGMESFIVVTECEPGCAVDLGLARDRPLEADGQEVPLDTSGSQARPHLSGRK
LSLQERSQGGLAAGGSLDMNGRCICPSLPYSPVSSPQSSPRLPRRPTVESHHVSITGMQDCVQLNQYTLKDEIGKGSYGVVKLAYNENDN
TYYNVLKEHADDDPSLAITGVPVVTWPKKTPKNRAVGRPKGKLGPASAVKLAANRTTAGARRRRTRCRKCEACLRTECGECHFCKDMKKF
GGPGRMKQSCIMRQCIAPVLPHTAVCLVCGEAGKEDTVEEEEGKFNLMLMECSICNEIIHPGCLKIKESEGVVNDELPNCWECPKCNHAG
KTGKQKRGPGFKYASNLPGSLLKEQKMNRDNKEGQEPAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEKPQELSGRK
RLKPGKEDKLFRKKRRSWKNAEDRMALANKPLRRFKQEPEDELPEAPPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNK
ELSRELSKELNHEIQRTENSLANENQQPIKSEPESEGEEPKRPPGICERPHRFSKGLNGTPRELRHQLGPSLRSPPRVISRPPPSVSPPK
CIQMERHVIRPPPISPPPDSLPLDDGAAHVMHREVWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIRR
QPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSSCPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRN
IVELRLAGLDITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDCNKVTDQCLSFFKRCGNICHIDLRYCK

--------------------------------------------------------------

>12706_12706_5_CAMKK2-KDM2B_CAMKK2_chr12_121707331_ENST00000337174_KDM2B_chr12_121932468_ENST00000377069_length(amino acids)=1020AA_BP=273
MEVDSPVNSIPFWLFGRVSETSPGSLDPVGRFREPSRSSFLLFPAQCCYPAGGSNAHLRLQQSGSAAGWECPSVLDEAGACTMSSCVSSQ
PSSNRAAPQDELGGRGSSSSESQKPCEALRGLSSLSIHLGMESFIVVTECEPGCAVDLGLARDRPLEADGQEVPLDTSGSQARPHLSGRK
LSLQERSQGGLAAGGSLDMNGRCICPSLPYSPVSSPQSSPRLPRRPTVESHHVSITGMQDCVQLNQYTLKDEIGKGSYGVVKLAYNENDN
TYYNVLKEHADDDPSLAITGVPVVTWPKKTPKNRAVGRPKGKLGPASAVKLAANRTTAGARRRRTRCRKCEACLRTECGECHFCKDMKKF
GGPGRMKQSCIMRQCIAPVLPHTAVCLVCGEAGKEDTVEEEEGKFNLMLMECSICNEIIHPGCLKIKESEGVVNDELPNCWECPKCNHAG
KTGKQKRGPGFKYASNLPGSLLKEQKMNRDNKEGQEPAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEKPQELSGRK
RLKPGKEDKLFRKKRRSWKNAEDRMALANKPLRRFKQEPEDELPEAPPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNK
ELSRELSKELNHEIQRTENSLANENQQPIKSEPESEGEEPKRPPGICERPHRFSKGLNGTPRELRHQLGPSLRSPPRVISRPPPSVSPPK
CIQMERHVIRPPPISPPPDSLPLDDGAAHVMHREVWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIRR
QPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSSCPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRN
IVELRLAGLDITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDCNKVTDQCLSFFKRCGNICHIDLRYCK

--------------------------------------------------------------

>12706_12706_6_CAMKK2-KDM2B_CAMKK2_chr12_121707331_ENST00000347034_KDM2B_chr12_121932468_ENST00000377069_length(amino acids)=1020AA_BP=273
MEVDSPVNSIPFWLFGRVSETSPGSLDPVGRFREPSRSSFLLFPAQCCYPAGGSNAHLRLQQSGSAAGWECPSVLDEAGACTMSSCVSSQ
PSSNRAAPQDELGGRGSSSSESQKPCEALRGLSSLSIHLGMESFIVVTECEPGCAVDLGLARDRPLEADGQEVPLDTSGSQARPHLSGRK
LSLQERSQGGLAAGGSLDMNGRCICPSLPYSPVSSPQSSPRLPRRPTVESHHVSITGMQDCVQLNQYTLKDEIGKGSYGVVKLAYNENDN
TYYNVLKEHADDDPSLAITGVPVVTWPKKTPKNRAVGRPKGKLGPASAVKLAANRTTAGARRRRTRCRKCEACLRTECGECHFCKDMKKF
GGPGRMKQSCIMRQCIAPVLPHTAVCLVCGEAGKEDTVEEEEGKFNLMLMECSICNEIIHPGCLKIKESEGVVNDELPNCWECPKCNHAG
KTGKQKRGPGFKYASNLPGSLLKEQKMNRDNKEGQEPAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEKPQELSGRK
RLKPGKEDKLFRKKRRSWKNAEDRMALANKPLRRFKQEPEDELPEAPPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNK
ELSRELSKELNHEIQRTENSLANENQQPIKSEPESEGEEPKRPPGICERPHRFSKGLNGTPRELRHQLGPSLRSPPRVISRPPPSVSPPK
CIQMERHVIRPPPISPPPDSLPLDDGAAHVMHREVWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIRR
QPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSSCPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRN
IVELRLAGLDITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDCNKVTDQCLSFFKRCGNICHIDLRYCK

--------------------------------------------------------------

>12706_12706_7_CAMKK2-KDM2B_CAMKK2_chr12_121707331_ENST00000392473_KDM2B_chr12_121932468_ENST00000377069_length(amino acids)=1020AA_BP=273
MEVDSPVNSIPFWLFGRVSETSPGSLDPVGRFREPSRSSFLLFPAQCCYPAGGSNAHLRLQQSGSAAGWECPSVLDEAGACTMSSCVSSQ
PSSNRAAPQDELGGRGSSSSESQKPCEALRGLSSLSIHLGMESFIVVTECEPGCAVDLGLARDRPLEADGQEVPLDTSGSQARPHLSGRK
LSLQERSQGGLAAGGSLDMNGRCICPSLPYSPVSSPQSSPRLPRRPTVESHHVSITGMQDCVQLNQYTLKDEIGKGSYGVVKLAYNENDN
TYYNVLKEHADDDPSLAITGVPVVTWPKKTPKNRAVGRPKGKLGPASAVKLAANRTTAGARRRRTRCRKCEACLRTECGECHFCKDMKKF
GGPGRMKQSCIMRQCIAPVLPHTAVCLVCGEAGKEDTVEEEEGKFNLMLMECSICNEIIHPGCLKIKESEGVVNDELPNCWECPKCNHAG
KTGKQKRGPGFKYASNLPGSLLKEQKMNRDNKEGQEPAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEKPQELSGRK
RLKPGKEDKLFRKKRRSWKNAEDRMALANKPLRRFKQEPEDELPEAPPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNK
ELSRELSKELNHEIQRTENSLANENQQPIKSEPESEGEEPKRPPGICERPHRFSKGLNGTPRELRHQLGPSLRSPPRVISRPPPSVSPPK
CIQMERHVIRPPPISPPPDSLPLDDGAAHVMHREVWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIRR
QPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSSCPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRN
IVELRLAGLDITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDCNKVTDQCLSFFKRCGNICHIDLRYCK

--------------------------------------------------------------

>12706_12706_8_CAMKK2-KDM2B_CAMKK2_chr12_121707331_ENST00000392474_KDM2B_chr12_121932468_ENST00000377069_length(amino acids)=938AA_BP=191
MSSCVSSQPSSNRAAPQDELGGRGSSSSESQKPCEALRGLSSLSIHLGMESFIVVTECEPGCAVDLGLARDRPLEADGQEVPLDTSGSQA
RPHLSGRKLSLQERSQGGLAAGGSLDMNGRCICPSLPYSPVSSPQSSPRLPRRPTVESHHVSITGMQDCVQLNQYTLKDEIGKGSYGVVK
LAYNENDNTYYNVLKEHADDDPSLAITGVPVVTWPKKTPKNRAVGRPKGKLGPASAVKLAANRTTAGARRRRTRCRKCEACLRTECGECH
FCKDMKKFGGPGRMKQSCIMRQCIAPVLPHTAVCLVCGEAGKEDTVEEEEGKFNLMLMECSICNEIIHPGCLKIKESEGVVNDELPNCWE
CPKCNHAGKTGKQKRGPGFKYASNLPGSLLKEQKMNRDNKEGQEPAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEK
PQELSGRKRLKPGKEDKLFRKKRRSWKNAEDRMALANKPLRRFKQEPEDELPEAPPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMR
RKRRLPNKELSRELSKELNHEIQRTENSLANENQQPIKSEPESEGEEPKRPPGICERPHRFSKGLNGTPRELRHQLGPSLRSPPRVISRP
PPSVSPPKCIQMERHVIRPPPISPPPDSLPLDDGAAHVMHREVWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITPL
MLSGIIRRQPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSSCPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQM
DNRSKLRNIVELRLAGLDITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDCNKVTDQCLSFFKRCGNIC

--------------------------------------------------------------

>12706_12706_9_CAMKK2-KDM2B_CAMKK2_chr12_121707331_ENST00000446440_KDM2B_chr12_121932468_ENST00000377069_length(amino acids)=1020AA_BP=273
MEVDSPVNSIPFWLFGRVSETSPGSLDPVGRFREPSRSSFLLFPAQCCYPAGGSNAHLRLQQSGSAAGWECPSVLDEAGACTMSSCVSSQ
PSSNRAAPQDELGGRGSSSSESQKPCEALRGLSSLSIHLGMESFIVVTECEPGCAVDLGLARDRPLEADGQEVPLDTSGSQARPHLSGRK
LSLQERSQGGLAAGGSLDMNGRCICPSLPYSPVSSPQSSPRLPRRPTVESHHVSITGMQDCVQLNQYTLKDEIGKGSYGVVKLAYNENDN
TYYNVLKEHADDDPSLAITGVPVVTWPKKTPKNRAVGRPKGKLGPASAVKLAANRTTAGARRRRTRCRKCEACLRTECGECHFCKDMKKF
GGPGRMKQSCIMRQCIAPVLPHTAVCLVCGEAGKEDTVEEEEGKFNLMLMECSICNEIIHPGCLKIKESEGVVNDELPNCWECPKCNHAG
KTGKQKRGPGFKYASNLPGSLLKEQKMNRDNKEGQEPAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEKPQELSGRK
RLKPGKEDKLFRKKRRSWKNAEDRMALANKPLRRFKQEPEDELPEAPPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNK
ELSRELSKELNHEIQRTENSLANENQQPIKSEPESEGEEPKRPPGICERPHRFSKGLNGTPRELRHQLGPSLRSPPRVISRPPPSVSPPK
CIQMERHVIRPPPISPPPDSLPLDDGAAHVMHREVWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIRR
QPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSSCPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRN
IVELRLAGLDITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDCNKVTDQCLSFFKRCGNICHIDLRYCK

--------------------------------------------------------------

>12706_12706_10_CAMKK2-KDM2B_CAMKK2_chr12_121707331_ENST00000538733_KDM2B_chr12_121932468_ENST00000377069_length(amino acids)=1020AA_BP=273
MEVDSPVNSIPFWLFGRVSETSPGSLDPVGRFREPSRSSFLLFPAQCCYPAGGSNAHLRLQQSGSAAGWECPSVLDEAGACTMSSCVSSQ
PSSNRAAPQDELGGRGSSSSESQKPCEALRGLSSLSIHLGMESFIVVTECEPGCAVDLGLARDRPLEADGQEVPLDTSGSQARPHLSGRK
LSLQERSQGGLAAGGSLDMNGRCICPSLPYSPVSSPQSSPRLPRRPTVESHHVSITGMQDCVQLNQYTLKDEIGKGSYGVVKLAYNENDN
TYYNVLKEHADDDPSLAITGVPVVTWPKKTPKNRAVGRPKGKLGPASAVKLAANRTTAGARRRRTRCRKCEACLRTECGECHFCKDMKKF
GGPGRMKQSCIMRQCIAPVLPHTAVCLVCGEAGKEDTVEEEEGKFNLMLMECSICNEIIHPGCLKIKESEGVVNDELPNCWECPKCNHAG
KTGKQKRGPGFKYASNLPGSLLKEQKMNRDNKEGQEPAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEKPQELSGRK
RLKPGKEDKLFRKKRRSWKNAEDRMALANKPLRRFKQEPEDELPEAPPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNK
ELSRELSKELNHEIQRTENSLANENQQPIKSEPESEGEEPKRPPGICERPHRFSKGLNGTPRELRHQLGPSLRSPPRVISRPPPSVSPPK
CIQMERHVIRPPPISPPPDSLPLDDGAAHVMHREVWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIRR
QPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSSCPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRN
IVELRLAGLDITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDCNKVTDQCLSFFKRCGNICHIDLRYCK

--------------------------------------------------------------

>12706_12706_11_CAMKK2-KDM2B_CAMKK2_chr12_121708701_ENST00000324774_KDM2B_chr12_121891147_ENST00000377069_length(amino acids)=973AA_BP=255
MEVDSPVNSIPFWLFGRVSETSPGSLDPVGRFREPSRSSFLLFPAQCCYPAGGSNAHLRLQQSGSAAGWECPSVLDEAGACTMSSCVSSQ
PSSNRAAPQDELGGRGSSSSESQKPCEALRGLSSLSIHLGMESFIVVTECEPGCAVDLGLARDRPLEADGQEVPLDTSGSQARPHLSGRK
LSLQERSQGGLAAGGSLDMNGRCICPSLPYSPVSSPQSSPRLPRRPTVESHHVSITGMQDCVQLNQYTLKDEIGKNRAVGRPKGKLGPAS
AVKLAANRTTAGARRRRTRCRKCEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQCIAPVLPHTAVCLVCGEAGKEDTVEEEEGKFNL
MLMECSICNEIIHPGCLKIKESEGVVNDELPNCWECPKCNHAGKTGKQKRGPGFKYASNLPGSLLKEQKMNRDNKEGQEPAKRRSECEEA
PRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEKPQELSGRKRLKPGKEDKLFRKKRRSWKNAEDRMALANKPLRRFKQEPEDELPEAP
PKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKELSRELSKELNHEIQRTENSLANENQQPIKSEPESEGEEPKRPPGIC
ERPHRFSKGLNGTPRELRHQLGPSLRSPPRVISRPPPSVSPPKCIQMERHVIRPPPISPPPDSLPLDDGAAHVMHREVWMAVFSYLSHQD
LCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIRRQPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSS
CPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLDITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLTA

--------------------------------------------------------------

>12706_12706_12_CAMKK2-KDM2B_CAMKK2_chr12_121708701_ENST00000337174_KDM2B_chr12_121891147_ENST00000377069_length(amino acids)=973AA_BP=255
MEVDSPVNSIPFWLFGRVSETSPGSLDPVGRFREPSRSSFLLFPAQCCYPAGGSNAHLRLQQSGSAAGWECPSVLDEAGACTMSSCVSSQ
PSSNRAAPQDELGGRGSSSSESQKPCEALRGLSSLSIHLGMESFIVVTECEPGCAVDLGLARDRPLEADGQEVPLDTSGSQARPHLSGRK
LSLQERSQGGLAAGGSLDMNGRCICPSLPYSPVSSPQSSPRLPRRPTVESHHVSITGMQDCVQLNQYTLKDEIGKNRAVGRPKGKLGPAS
AVKLAANRTTAGARRRRTRCRKCEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQCIAPVLPHTAVCLVCGEAGKEDTVEEEEGKFNL
MLMECSICNEIIHPGCLKIKESEGVVNDELPNCWECPKCNHAGKTGKQKRGPGFKYASNLPGSLLKEQKMNRDNKEGQEPAKRRSECEEA
PRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEKPQELSGRKRLKPGKEDKLFRKKRRSWKNAEDRMALANKPLRRFKQEPEDELPEAP
PKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKELSRELSKELNHEIQRTENSLANENQQPIKSEPESEGEEPKRPPGIC
ERPHRFSKGLNGTPRELRHQLGPSLRSPPRVISRPPPSVSPPKCIQMERHVIRPPPISPPPDSLPLDDGAAHVMHREVWMAVFSYLSHQD
LCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIRRQPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSS
CPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLDITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLTA

--------------------------------------------------------------

>12706_12706_13_CAMKK2-KDM2B_CAMKK2_chr12_121708701_ENST00000347034_KDM2B_chr12_121891147_ENST00000377069_length(amino acids)=973AA_BP=255
MEVDSPVNSIPFWLFGRVSETSPGSLDPVGRFREPSRSSFLLFPAQCCYPAGGSNAHLRLQQSGSAAGWECPSVLDEAGACTMSSCVSSQ
PSSNRAAPQDELGGRGSSSSESQKPCEALRGLSSLSIHLGMESFIVVTECEPGCAVDLGLARDRPLEADGQEVPLDTSGSQARPHLSGRK
LSLQERSQGGLAAGGSLDMNGRCICPSLPYSPVSSPQSSPRLPRRPTVESHHVSITGMQDCVQLNQYTLKDEIGKNRAVGRPKGKLGPAS
AVKLAANRTTAGARRRRTRCRKCEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQCIAPVLPHTAVCLVCGEAGKEDTVEEEEGKFNL
MLMECSICNEIIHPGCLKIKESEGVVNDELPNCWECPKCNHAGKTGKQKRGPGFKYASNLPGSLLKEQKMNRDNKEGQEPAKRRSECEEA
PRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEKPQELSGRKRLKPGKEDKLFRKKRRSWKNAEDRMALANKPLRRFKQEPEDELPEAP
PKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKELSRELSKELNHEIQRTENSLANENQQPIKSEPESEGEEPKRPPGIC
ERPHRFSKGLNGTPRELRHQLGPSLRSPPRVISRPPPSVSPPKCIQMERHVIRPPPISPPPDSLPLDDGAAHVMHREVWMAVFSYLSHQD
LCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIRRQPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSS
CPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLDITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLTA

--------------------------------------------------------------

>12706_12706_14_CAMKK2-KDM2B_CAMKK2_chr12_121708701_ENST00000392473_KDM2B_chr12_121891147_ENST00000377069_length(amino acids)=973AA_BP=255
MEVDSPVNSIPFWLFGRVSETSPGSLDPVGRFREPSRSSFLLFPAQCCYPAGGSNAHLRLQQSGSAAGWECPSVLDEAGACTMSSCVSSQ
PSSNRAAPQDELGGRGSSSSESQKPCEALRGLSSLSIHLGMESFIVVTECEPGCAVDLGLARDRPLEADGQEVPLDTSGSQARPHLSGRK
LSLQERSQGGLAAGGSLDMNGRCICPSLPYSPVSSPQSSPRLPRRPTVESHHVSITGMQDCVQLNQYTLKDEIGKNRAVGRPKGKLGPAS
AVKLAANRTTAGARRRRTRCRKCEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQCIAPVLPHTAVCLVCGEAGKEDTVEEEEGKFNL
MLMECSICNEIIHPGCLKIKESEGVVNDELPNCWECPKCNHAGKTGKQKRGPGFKYASNLPGSLLKEQKMNRDNKEGQEPAKRRSECEEA
PRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEKPQELSGRKRLKPGKEDKLFRKKRRSWKNAEDRMALANKPLRRFKQEPEDELPEAP
PKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKELSRELSKELNHEIQRTENSLANENQQPIKSEPESEGEEPKRPPGIC
ERPHRFSKGLNGTPRELRHQLGPSLRSPPRVISRPPPSVSPPKCIQMERHVIRPPPISPPPDSLPLDDGAAHVMHREVWMAVFSYLSHQD
LCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIRRQPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSS
CPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLDITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLTA

--------------------------------------------------------------

>12706_12706_15_CAMKK2-KDM2B_CAMKK2_chr12_121708701_ENST00000392474_KDM2B_chr12_121891147_ENST00000377069_length(amino acids)=891AA_BP=173
MSSCVSSQPSSNRAAPQDELGGRGSSSSESQKPCEALRGLSSLSIHLGMESFIVVTECEPGCAVDLGLARDRPLEADGQEVPLDTSGSQA
RPHLSGRKLSLQERSQGGLAAGGSLDMNGRCICPSLPYSPVSSPQSSPRLPRRPTVESHHVSITGMQDCVQLNQYTLKDEIGKNRAVGRP
KGKLGPASAVKLAANRTTAGARRRRTRCRKCEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQCIAPVLPHTAVCLVCGEAGKEDTVE
EEEGKFNLMLMECSICNEIIHPGCLKIKESEGVVNDELPNCWECPKCNHAGKTGKQKRGPGFKYASNLPGSLLKEQKMNRDNKEGQEPAK
RRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEKPQELSGRKRLKPGKEDKLFRKKRRSWKNAEDRMALANKPLRRFKQEP
EDELPEAPPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKELSRELSKELNHEIQRTENSLANENQQPIKSEPESEGEE
PKRPPGICERPHRFSKGLNGTPRELRHQLGPSLRSPPRVISRPPPSVSPPKCIQMERHVIRPPPISPPPDSLPLDDGAAHVMHREVWMAV
FSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIRRQPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIA
VSALCSSSCPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLDITDASLRLIIRHMPLLSKLHLSYCNHVTD

--------------------------------------------------------------

>12706_12706_16_CAMKK2-KDM2B_CAMKK2_chr12_121708701_ENST00000446440_KDM2B_chr12_121891147_ENST00000377069_length(amino acids)=973AA_BP=255
MEVDSPVNSIPFWLFGRVSETSPGSLDPVGRFREPSRSSFLLFPAQCCYPAGGSNAHLRLQQSGSAAGWECPSVLDEAGACTMSSCVSSQ
PSSNRAAPQDELGGRGSSSSESQKPCEALRGLSSLSIHLGMESFIVVTECEPGCAVDLGLARDRPLEADGQEVPLDTSGSQARPHLSGRK
LSLQERSQGGLAAGGSLDMNGRCICPSLPYSPVSSPQSSPRLPRRPTVESHHVSITGMQDCVQLNQYTLKDEIGKNRAVGRPKGKLGPAS
AVKLAANRTTAGARRRRTRCRKCEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQCIAPVLPHTAVCLVCGEAGKEDTVEEEEGKFNL
MLMECSICNEIIHPGCLKIKESEGVVNDELPNCWECPKCNHAGKTGKQKRGPGFKYASNLPGSLLKEQKMNRDNKEGQEPAKRRSECEEA
PRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEKPQELSGRKRLKPGKEDKLFRKKRRSWKNAEDRMALANKPLRRFKQEPEDELPEAP
PKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKELSRELSKELNHEIQRTENSLANENQQPIKSEPESEGEEPKRPPGIC
ERPHRFSKGLNGTPRELRHQLGPSLRSPPRVISRPPPSVSPPKCIQMERHVIRPPPISPPPDSLPLDDGAAHVMHREVWMAVFSYLSHQD
LCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIRRQPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSS
CPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLDITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLTA

--------------------------------------------------------------

>12706_12706_17_CAMKK2-KDM2B_CAMKK2_chr12_121708701_ENST00000538733_KDM2B_chr12_121891147_ENST00000377069_length(amino acids)=973AA_BP=255
MEVDSPVNSIPFWLFGRVSETSPGSLDPVGRFREPSRSSFLLFPAQCCYPAGGSNAHLRLQQSGSAAGWECPSVLDEAGACTMSSCVSSQ
PSSNRAAPQDELGGRGSSSSESQKPCEALRGLSSLSIHLGMESFIVVTECEPGCAVDLGLARDRPLEADGQEVPLDTSGSQARPHLSGRK
LSLQERSQGGLAAGGSLDMNGRCICPSLPYSPVSSPQSSPRLPRRPTVESHHVSITGMQDCVQLNQYTLKDEIGKNRAVGRPKGKLGPAS
AVKLAANRTTAGARRRRTRCRKCEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQCIAPVLPHTAVCLVCGEAGKEDTVEEEEGKFNL
MLMECSICNEIIHPGCLKIKESEGVVNDELPNCWECPKCNHAGKTGKQKRGPGFKYASNLPGSLLKEQKMNRDNKEGQEPAKRRSECEEA
PRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEKPQELSGRKRLKPGKEDKLFRKKRRSWKNAEDRMALANKPLRRFKQEPEDELPEAP
PKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKELSRELSKELNHEIQRTENSLANENQQPIKSEPESEGEEPKRPPGIC
ERPHRFSKGLNGTPRELRHQLGPSLRSPPRVISRPPPSVSPPKCIQMERHVIRPPPISPPPDSLPLDDGAAHVMHREVWMAVFSYLSHQD
LCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIRRQPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSS
CPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLDITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLTA

--------------------------------------------------------------

>12706_12706_18_CAMKK2-KDM2B_CAMKK2_chr12_121711859_ENST00000324774_KDM2B_chr12_121932468_ENST00000377069_length(amino acids)=986AA_BP=238
MEVDSPVNSIPFWLFGRVSETSPGSLDPVGRFREPSRSSFLLFPAQCCYPAGGSNAHLRLQQSGSAAGWECPSVLDEAGACTMSSCVSSQ
PSSNRAAPQDELGGRGSSSSESQKPCEALRGLSSLSIHLGMESFIVVTECEPGCAVDLGLARDRPLEADGQEVPLDTSGSQARPHLSGRK
LSLQERSQGGLAAGGSLDMNGRCICPSLPYSPVSSPQSSPRLPRRPTVESHHVSITGMQNVLKEHADDDPSLAITGVPVVTWPKKTPKNR
AVGRPKGKLGPASAVKLAANRTTAGARRRRTRCRKCEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQCIAPVLPHTAVCLVCGEAGK
EDTVEEEEGKFNLMLMECSICNEIIHPGCLKIKESEGVVNDELPNCWECPKCNHAGKTGKQKRGPGFKYASNLPGSLLKEQKMNRDNKEG
QEPAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEKPQELSGRKRLKPGKEDKLFRKKRRSWKNAEDRMALANKPLRR
FKQEPEDELPEAPPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKELSRELSKELNHEIQRTENSLANENQQPIKSEPE
SEGEEPKRPPGICERPHRFSKGLNGTPRELRHQLGPSLRSPPRVISRPPPSVSPPKCIQMERHVIRPPPISPPPDSLPLDDGAAHVMHRE
VWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIRRQPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSG
CSWIAVSALCSSSCPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLDITDASLRLIIRHMPLLSKLHLSYC

--------------------------------------------------------------

>12706_12706_19_CAMKK2-KDM2B_CAMKK2_chr12_121711859_ENST00000337174_KDM2B_chr12_121932468_ENST00000377069_length(amino acids)=986AA_BP=238
MEVDSPVNSIPFWLFGRVSETSPGSLDPVGRFREPSRSSFLLFPAQCCYPAGGSNAHLRLQQSGSAAGWECPSVLDEAGACTMSSCVSSQ
PSSNRAAPQDELGGRGSSSSESQKPCEALRGLSSLSIHLGMESFIVVTECEPGCAVDLGLARDRPLEADGQEVPLDTSGSQARPHLSGRK
LSLQERSQGGLAAGGSLDMNGRCICPSLPYSPVSSPQSSPRLPRRPTVESHHVSITGMQNVLKEHADDDPSLAITGVPVVTWPKKTPKNR
AVGRPKGKLGPASAVKLAANRTTAGARRRRTRCRKCEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQCIAPVLPHTAVCLVCGEAGK
EDTVEEEEGKFNLMLMECSICNEIIHPGCLKIKESEGVVNDELPNCWECPKCNHAGKTGKQKRGPGFKYASNLPGSLLKEQKMNRDNKEG
QEPAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEKPQELSGRKRLKPGKEDKLFRKKRRSWKNAEDRMALANKPLRR
FKQEPEDELPEAPPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKELSRELSKELNHEIQRTENSLANENQQPIKSEPE
SEGEEPKRPPGICERPHRFSKGLNGTPRELRHQLGPSLRSPPRVISRPPPSVSPPKCIQMERHVIRPPPISPPPDSLPLDDGAAHVMHRE
VWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIRRQPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSG
CSWIAVSALCSSSCPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLDITDASLRLIIRHMPLLSKLHLSYC

--------------------------------------------------------------

>12706_12706_20_CAMKK2-KDM2B_CAMKK2_chr12_121711859_ENST00000347034_KDM2B_chr12_121932468_ENST00000377069_length(amino acids)=986AA_BP=238
MEVDSPVNSIPFWLFGRVSETSPGSLDPVGRFREPSRSSFLLFPAQCCYPAGGSNAHLRLQQSGSAAGWECPSVLDEAGACTMSSCVSSQ
PSSNRAAPQDELGGRGSSSSESQKPCEALRGLSSLSIHLGMESFIVVTECEPGCAVDLGLARDRPLEADGQEVPLDTSGSQARPHLSGRK
LSLQERSQGGLAAGGSLDMNGRCICPSLPYSPVSSPQSSPRLPRRPTVESHHVSITGMQNVLKEHADDDPSLAITGVPVVTWPKKTPKNR
AVGRPKGKLGPASAVKLAANRTTAGARRRRTRCRKCEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQCIAPVLPHTAVCLVCGEAGK
EDTVEEEEGKFNLMLMECSICNEIIHPGCLKIKESEGVVNDELPNCWECPKCNHAGKTGKQKRGPGFKYASNLPGSLLKEQKMNRDNKEG
QEPAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEKPQELSGRKRLKPGKEDKLFRKKRRSWKNAEDRMALANKPLRR
FKQEPEDELPEAPPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKELSRELSKELNHEIQRTENSLANENQQPIKSEPE
SEGEEPKRPPGICERPHRFSKGLNGTPRELRHQLGPSLRSPPRVISRPPPSVSPPKCIQMERHVIRPPPISPPPDSLPLDDGAAHVMHRE
VWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIRRQPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSG
CSWIAVSALCSSSCPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLDITDASLRLIIRHMPLLSKLHLSYC

--------------------------------------------------------------

>12706_12706_21_CAMKK2-KDM2B_CAMKK2_chr12_121711859_ENST00000392473_KDM2B_chr12_121932468_ENST00000377069_length(amino acids)=986AA_BP=238
MEVDSPVNSIPFWLFGRVSETSPGSLDPVGRFREPSRSSFLLFPAQCCYPAGGSNAHLRLQQSGSAAGWECPSVLDEAGACTMSSCVSSQ
PSSNRAAPQDELGGRGSSSSESQKPCEALRGLSSLSIHLGMESFIVVTECEPGCAVDLGLARDRPLEADGQEVPLDTSGSQARPHLSGRK
LSLQERSQGGLAAGGSLDMNGRCICPSLPYSPVSSPQSSPRLPRRPTVESHHVSITGMQNVLKEHADDDPSLAITGVPVVTWPKKTPKNR
AVGRPKGKLGPASAVKLAANRTTAGARRRRTRCRKCEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQCIAPVLPHTAVCLVCGEAGK
EDTVEEEEGKFNLMLMECSICNEIIHPGCLKIKESEGVVNDELPNCWECPKCNHAGKTGKQKRGPGFKYASNLPGSLLKEQKMNRDNKEG
QEPAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEKPQELSGRKRLKPGKEDKLFRKKRRSWKNAEDRMALANKPLRR
FKQEPEDELPEAPPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKELSRELSKELNHEIQRTENSLANENQQPIKSEPE
SEGEEPKRPPGICERPHRFSKGLNGTPRELRHQLGPSLRSPPRVISRPPPSVSPPKCIQMERHVIRPPPISPPPDSLPLDDGAAHVMHRE
VWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIRRQPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSG
CSWIAVSALCSSSCPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLDITDASLRLIIRHMPLLSKLHLSYC

--------------------------------------------------------------

>12706_12706_22_CAMKK2-KDM2B_CAMKK2_chr12_121711859_ENST00000392474_KDM2B_chr12_121932468_ENST00000377069_length(amino acids)=904AA_BP=156
MSSCVSSQPSSNRAAPQDELGGRGSSSSESQKPCEALRGLSSLSIHLGMESFIVVTECEPGCAVDLGLARDRPLEADGQEVPLDTSGSQA
RPHLSGRKLSLQERSQGGLAAGGSLDMNGRCICPSLPYSPVSSPQSSPRLPRRPTVESHHVSITGMQNVLKEHADDDPSLAITGVPVVTW
PKKTPKNRAVGRPKGKLGPASAVKLAANRTTAGARRRRTRCRKCEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQCIAPVLPHTAVC
LVCGEAGKEDTVEEEEGKFNLMLMECSICNEIIHPGCLKIKESEGVVNDELPNCWECPKCNHAGKTGKQKRGPGFKYASNLPGSLLKEQK
MNRDNKEGQEPAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEKPQELSGRKRLKPGKEDKLFRKKRRSWKNAEDRMA
LANKPLRRFKQEPEDELPEAPPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKELSRELSKELNHEIQRTENSLANENQ
QPIKSEPESEGEEPKRPPGICERPHRFSKGLNGTPRELRHQLGPSLRSPPRVISRPPPSVSPPKCIQMERHVIRPPPISPPPDSLPLDDG
AAHVMHREVWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIRRQPVSLDLSWTNISKKQLSWLINRLPG
LRDLVLSGCSWIAVSALCSSSCPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLDITDASLRLIIRHMPLL
SKLHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDCNKVTDQCLSFFKRCGNICHIDLRYCKQVTKEGCEQFIAEMSSFQGRSCSTTR

--------------------------------------------------------------

>12706_12706_23_CAMKK2-KDM2B_CAMKK2_chr12_121711859_ENST00000446440_KDM2B_chr12_121932468_ENST00000377069_length(amino acids)=986AA_BP=238
MEVDSPVNSIPFWLFGRVSETSPGSLDPVGRFREPSRSSFLLFPAQCCYPAGGSNAHLRLQQSGSAAGWECPSVLDEAGACTMSSCVSSQ
PSSNRAAPQDELGGRGSSSSESQKPCEALRGLSSLSIHLGMESFIVVTECEPGCAVDLGLARDRPLEADGQEVPLDTSGSQARPHLSGRK
LSLQERSQGGLAAGGSLDMNGRCICPSLPYSPVSSPQSSPRLPRRPTVESHHVSITGMQNVLKEHADDDPSLAITGVPVVTWPKKTPKNR
AVGRPKGKLGPASAVKLAANRTTAGARRRRTRCRKCEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQCIAPVLPHTAVCLVCGEAGK
EDTVEEEEGKFNLMLMECSICNEIIHPGCLKIKESEGVVNDELPNCWECPKCNHAGKTGKQKRGPGFKYASNLPGSLLKEQKMNRDNKEG
QEPAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEKPQELSGRKRLKPGKEDKLFRKKRRSWKNAEDRMALANKPLRR
FKQEPEDELPEAPPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKELSRELSKELNHEIQRTENSLANENQQPIKSEPE
SEGEEPKRPPGICERPHRFSKGLNGTPRELRHQLGPSLRSPPRVISRPPPSVSPPKCIQMERHVIRPPPISPPPDSLPLDDGAAHVMHRE
VWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIRRQPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSG
CSWIAVSALCSSSCPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLDITDASLRLIIRHMPLLSKLHLSYC

--------------------------------------------------------------

>12706_12706_24_CAMKK2-KDM2B_CAMKK2_chr12_121711859_ENST00000538733_KDM2B_chr12_121932468_ENST00000377069_length(amino acids)=986AA_BP=238
MEVDSPVNSIPFWLFGRVSETSPGSLDPVGRFREPSRSSFLLFPAQCCYPAGGSNAHLRLQQSGSAAGWECPSVLDEAGACTMSSCVSSQ
PSSNRAAPQDELGGRGSSSSESQKPCEALRGLSSLSIHLGMESFIVVTECEPGCAVDLGLARDRPLEADGQEVPLDTSGSQARPHLSGRK
LSLQERSQGGLAAGGSLDMNGRCICPSLPYSPVSSPQSSPRLPRRPTVESHHVSITGMQNVLKEHADDDPSLAITGVPVVTWPKKTPKNR
AVGRPKGKLGPASAVKLAANRTTAGARRRRTRCRKCEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQCIAPVLPHTAVCLVCGEAGK
EDTVEEEEGKFNLMLMECSICNEIIHPGCLKIKESEGVVNDELPNCWECPKCNHAGKTGKQKRGPGFKYASNLPGSLLKEQKMNRDNKEG
QEPAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEKPQELSGRKRLKPGKEDKLFRKKRRSWKNAEDRMALANKPLRR
FKQEPEDELPEAPPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKELSRELSKELNHEIQRTENSLANENQQPIKSEPE
SEGEEPKRPPGICERPHRFSKGLNGTPRELRHQLGPSLRSPPRVISRPPPSVSPPKCIQMERHVIRPPPISPPPDSLPLDDGAAHVMHRE
VWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIRRQPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSG
CSWIAVSALCSSSCPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLDITDASLRLIIRHMPLLSKLHLSYC

--------------------------------------------------------------

Top

Fusion Protein Functional Features


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:121708701/chr12:121891147)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CAMKK2

Q96RR4

KDM2B

Q8NHM5

FUNCTION: Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Isoform 1, isoform 2 and isoform 3 phosphorylate CAMK1 and CAMK4. Isoform 3 phosphorylates CAMK1D. Isoform 4, isoform 5 and isoform 6 lacking part of the calmodulin-binding domain are inactive. Efficiently phosphorylates 5'-AMP-activated protein kinase (AMPK) trimer, including that consisting of PRKAA1, PRKAB1 and PRKAG1. This phosphorylation is stimulated in response to Ca(2+) signals (By similarity). Seems to be involved in hippocampal activation of CREB1 (By similarity). May play a role in neurite growth. Isoform 3 may promote neurite elongation, while isoform 1 may promoter neurite branching. {ECO:0000250, ECO:0000269|PubMed:11395482, ECO:0000269|PubMed:12935886, ECO:0000269|PubMed:21957496, ECO:0000269|PubMed:9662074}.FUNCTION: Histone demethylase that demethylates 'Lys-4' and 'Lys-36' of histone H3, thereby playing a central role in histone code (PubMed:16362057, PubMed:17994099, PubMed:26237645). Preferentially demethylates trimethylated H3 'Lys-4' and dimethylated H3 'Lys-36' residue while it has weak or no activity for mono- and tri-methylated H3 'Lys-36' (PubMed:16362057, PubMed:17994099, PubMed:26237645). Preferentially binds the transcribed region of ribosomal RNA and represses the transcription of ribosomal RNA genes which inhibits cell growth and proliferation (PubMed:16362057, PubMed:17994099). May also serve as a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex (Probable). {ECO:0000269|PubMed:16362057, ECO:0000269|PubMed:17994099, ECO:0000269|PubMed:26237645, ECO:0000305}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

* Minus value of BPloci means that the break pointn is located before the CDS.
- Retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCAMKK2chr12:121682943chr12:121891147ENST00000324774-1517165_446517.6666666666666589.0DomainProtein kinase
HgeneCAMKK2chr12:121682943chr12:121891147ENST00000337174-1516165_446517.6666666666666542.0DomainProtein kinase
HgeneCAMKK2chr12:121682943chr12:121891147ENST00000347034-1416165_446474.6666666666667546.0DomainProtein kinase
HgeneCAMKK2chr12:121682943chr12:121891147ENST00000392473-1517165_446517.6666666666666534.0DomainProtein kinase
HgeneCAMKK2chr12:121682943chr12:121891147ENST00000392474-1416165_446517.6666666666666557.0DomainProtein kinase
HgeneCAMKK2chr12:121682943chr12:121891147ENST00000402834-1517165_446517.6666666666666589.0DomainProtein kinase
HgeneCAMKK2chr12:121682943chr12:121891147ENST00000404169-1517165_446517.6666666666666589.0DomainProtein kinase
HgeneCAMKK2chr12:121682943chr12:121891147ENST00000412367-1516165_446517.6666666666666542.0DomainProtein kinase
HgeneCAMKK2chr12:121682943chr12:121891147ENST00000446440-1416165_446474.6666666666667491.0DomainProtein kinase
HgeneCAMKK2chr12:121682943chr12:121891147ENST00000538733-1415165_446474.6666666666667499.0DomainProtein kinase
HgeneCAMKK2chr12:121682943chr12:121891147ENST00000324774-1517171_179517.6666666666666589.0Nucleotide bindingATP
HgeneCAMKK2chr12:121682943chr12:121891147ENST00000337174-1516171_179517.6666666666666542.0Nucleotide bindingATP
HgeneCAMKK2chr12:121682943chr12:121891147ENST00000347034-1416171_179474.6666666666667546.0Nucleotide bindingATP
HgeneCAMKK2chr12:121682943chr12:121891147ENST00000392473-1517171_179517.6666666666666534.0Nucleotide bindingATP
HgeneCAMKK2chr12:121682943chr12:121891147ENST00000392474-1416171_179517.6666666666666557.0Nucleotide bindingATP
HgeneCAMKK2chr12:121682943chr12:121891147ENST00000402834-1517171_179517.6666666666666589.0Nucleotide bindingATP
HgeneCAMKK2chr12:121682943chr12:121891147ENST00000404169-1517171_179517.6666666666666589.0Nucleotide bindingATP
HgeneCAMKK2chr12:121682943chr12:121891147ENST00000412367-1516171_179517.6666666666666542.0Nucleotide bindingATP
HgeneCAMKK2chr12:121682943chr12:121891147ENST00000446440-1416171_179474.6666666666667491.0Nucleotide bindingATP
HgeneCAMKK2chr12:121682943chr12:121891147ENST00000538733-1415171_179474.6666666666667499.0Nucleotide bindingATP
HgeneCAMKK2chr12:121707331chr12:121932468ENST00000324774-417171_179191.0589.0Nucleotide bindingATP
HgeneCAMKK2chr12:121707331chr12:121932468ENST00000337174-416171_179191.0542.0Nucleotide bindingATP
HgeneCAMKK2chr12:121707331chr12:121932468ENST00000347034-416171_179191.0546.0Nucleotide bindingATP
HgeneCAMKK2chr12:121707331chr12:121932468ENST00000392473-417171_179191.0534.0Nucleotide bindingATP
HgeneCAMKK2chr12:121707331chr12:121932468ENST00000392474-316171_179191.0557.0Nucleotide bindingATP
HgeneCAMKK2chr12:121707331chr12:121932468ENST00000402834-417171_179191.0589.0Nucleotide bindingATP
HgeneCAMKK2chr12:121707331chr12:121932468ENST00000404169-417171_179191.0589.0Nucleotide bindingATP
HgeneCAMKK2chr12:121707331chr12:121932468ENST00000412367-416171_179191.0542.0Nucleotide bindingATP
HgeneCAMKK2chr12:121707331chr12:121932468ENST00000446440-416171_179191.0491.0Nucleotide bindingATP
HgeneCAMKK2chr12:121707331chr12:121932468ENST00000538733-415171_179191.0499.0Nucleotide bindingATP
HgeneCAMKK2chr12:121682943chr12:121891147ENST00000324774-1517204_226517.6666666666666589.0RegionNote=RP domain
HgeneCAMKK2chr12:121682943chr12:121891147ENST00000324774-1517472_477517.6666666666666589.0RegionAutoinhibitory domain
HgeneCAMKK2chr12:121682943chr12:121891147ENST00000324774-1517475_500517.6666666666666589.0RegionCalmodulin-binding
HgeneCAMKK2chr12:121682943chr12:121891147ENST00000337174-1516204_226517.6666666666666542.0RegionNote=RP domain
HgeneCAMKK2chr12:121682943chr12:121891147ENST00000337174-1516472_477517.6666666666666542.0RegionAutoinhibitory domain
HgeneCAMKK2chr12:121682943chr12:121891147ENST00000337174-1516475_500517.6666666666666542.0RegionCalmodulin-binding
HgeneCAMKK2chr12:121682943chr12:121891147ENST00000347034-1416204_226474.6666666666667546.0RegionNote=RP domain
HgeneCAMKK2chr12:121682943chr12:121891147ENST00000347034-1416472_477474.6666666666667546.0RegionAutoinhibitory domain
HgeneCAMKK2chr12:121682943chr12:121891147ENST00000392473-1517204_226517.6666666666666534.0RegionNote=RP domain
HgeneCAMKK2chr12:121682943chr12:121891147ENST00000392473-1517472_477517.6666666666666534.0RegionAutoinhibitory domain
HgeneCAMKK2chr12:121682943chr12:121891147ENST00000392473-1517475_500517.6666666666666534.0RegionCalmodulin-binding
HgeneCAMKK2chr12:121682943chr12:121891147ENST00000392474-1416204_226517.6666666666666557.0RegionNote=RP domain
HgeneCAMKK2chr12:121682943chr12:121891147ENST00000392474-1416472_477517.6666666666666557.0RegionAutoinhibitory domain
HgeneCAMKK2chr12:121682943chr12:121891147ENST00000392474-1416475_500517.6666666666666557.0RegionCalmodulin-binding
HgeneCAMKK2chr12:121682943chr12:121891147ENST00000402834-1517204_226517.6666666666666589.0RegionNote=RP domain
HgeneCAMKK2chr12:121682943chr12:121891147ENST00000402834-1517472_477517.6666666666666589.0RegionAutoinhibitory domain
HgeneCAMKK2chr12:121682943chr12:121891147ENST00000402834-1517475_500517.6666666666666589.0RegionCalmodulin-binding
HgeneCAMKK2chr12:121682943chr12:121891147ENST00000404169-1517204_226517.6666666666666589.0RegionNote=RP domain
HgeneCAMKK2chr12:121682943chr12:121891147ENST00000404169-1517472_477517.6666666666666589.0RegionAutoinhibitory domain
HgeneCAMKK2chr12:121682943chr12:121891147ENST00000404169-1517475_500517.6666666666666589.0RegionCalmodulin-binding
HgeneCAMKK2chr12:121682943chr12:121891147ENST00000412367-1516204_226517.6666666666666542.0RegionNote=RP domain
HgeneCAMKK2chr12:121682943chr12:121891147ENST00000412367-1516472_477517.6666666666666542.0RegionAutoinhibitory domain
HgeneCAMKK2chr12:121682943chr12:121891147ENST00000412367-1516475_500517.6666666666666542.0RegionCalmodulin-binding
HgeneCAMKK2chr12:121682943chr12:121891147ENST00000446440-1416204_226474.6666666666667491.0RegionNote=RP domain
HgeneCAMKK2chr12:121682943chr12:121891147ENST00000446440-1416472_477474.6666666666667491.0RegionAutoinhibitory domain
HgeneCAMKK2chr12:121682943chr12:121891147ENST00000538733-1415204_226474.6666666666667499.0RegionNote=RP domain
HgeneCAMKK2chr12:121682943chr12:121891147ENST00000538733-1415472_477474.6666666666667499.0RegionAutoinhibitory domain
TgeneKDM2Bchr12:121682943chr12:121891147ENST000003770691123943_971547.01266.0Coiled coilOntology_term=ECO:0000255
TgeneKDM2Bchr12:121682943chr12:121891147ENST000003770711123943_971578.01337.0Coiled coilOntology_term=ECO:0000255
TgeneKDM2Bchr12:121682943chr12:121891147ENST00000542973114943_9710912.0Coiled coilOntology_term=ECO:0000255
TgeneKDM2Bchr12:121707331chr12:121932468ENST000003770691023943_971518.01266.0Coiled coilOntology_term=ECO:0000255
TgeneKDM2Bchr12:121707331chr12:121932468ENST000003770711023943_971549.01337.0Coiled coilOntology_term=ECO:0000255
TgeneKDM2Bchr12:121707331chr12:121932468ENST00000542973014943_9710912.0Coiled coilOntology_term=ECO:0000255
TgeneKDM2Bchr12:121708701chr12:121891147ENST000003770691123943_971547.01266.0Coiled coilOntology_term=ECO:0000255
TgeneKDM2Bchr12:121708701chr12:121891147ENST000003770711123943_971578.01337.0Coiled coilOntology_term=ECO:0000255
TgeneKDM2Bchr12:121708701chr12:121891147ENST00000542973114943_9710912.0Coiled coilOntology_term=ECO:0000255
TgeneKDM2Bchr12:121711859chr12:121932468ENST000003770691023943_971518.01266.0Coiled coilOntology_term=ECO:0000255
TgeneKDM2Bchr12:121711859chr12:121932468ENST000003770711023943_971549.01337.0Coiled coilOntology_term=ECO:0000255
TgeneKDM2Bchr12:121711859chr12:121932468ENST00000542973014943_9710912.0Coiled coilOntology_term=ECO:0000255
TgeneKDM2Bchr12:121682943chr12:121891147ENST0000037706911231014_1056547.01266.0Compositional biasNote=Pro-rich
TgeneKDM2Bchr12:121682943chr12:121891147ENST0000037707111231014_1056578.01337.0Compositional biasNote=Pro-rich
TgeneKDM2Bchr12:121682943chr12:121891147ENST000005429731141014_10560912.0Compositional biasNote=Pro-rich
TgeneKDM2Bchr12:121682943chr12:121891147ENST00000542973114409_4300912.0Compositional biasNote=Glu-rich
TgeneKDM2Bchr12:121707331chr12:121932468ENST0000037706910231014_1056518.01266.0Compositional biasNote=Pro-rich
TgeneKDM2Bchr12:121707331chr12:121932468ENST0000037707110231014_1056549.01337.0Compositional biasNote=Pro-rich
TgeneKDM2Bchr12:121707331chr12:121932468ENST000005429730141014_10560912.0Compositional biasNote=Pro-rich
TgeneKDM2Bchr12:121707331chr12:121932468ENST00000542973014409_4300912.0Compositional biasNote=Glu-rich
TgeneKDM2Bchr12:121708701chr12:121891147ENST0000037706911231014_1056547.01266.0Compositional biasNote=Pro-rich
TgeneKDM2Bchr12:121708701chr12:121891147ENST0000037707111231014_1056578.01337.0Compositional biasNote=Pro-rich
TgeneKDM2Bchr12:121708701chr12:121891147ENST000005429731141014_10560912.0Compositional biasNote=Pro-rich
TgeneKDM2Bchr12:121708701chr12:121891147ENST00000542973114409_4300912.0Compositional biasNote=Glu-rich
TgeneKDM2Bchr12:121711859chr12:121932468ENST0000037706910231014_1056518.01266.0Compositional biasNote=Pro-rich
TgeneKDM2Bchr12:121711859chr12:121932468ENST0000037707110231014_1056549.01337.0Compositional biasNote=Pro-rich
TgeneKDM2Bchr12:121711859chr12:121932468ENST000005429730141014_10560912.0Compositional biasNote=Pro-rich
TgeneKDM2Bchr12:121711859chr12:121932468ENST00000542973014409_4300912.0Compositional biasNote=Glu-rich
TgeneKDM2Bchr12:121682943chr12:121891147ENST0000037706911231059_1105547.01266.0DomainNote=F-box
TgeneKDM2Bchr12:121682943chr12:121891147ENST0000037707111231059_1105578.01337.0DomainNote=F-box
TgeneKDM2Bchr12:121682943chr12:121891147ENST000005429731141059_11050912.0DomainNote=F-box
TgeneKDM2Bchr12:121682943chr12:121891147ENST00000542973114178_3460912.0DomainJmjC
TgeneKDM2Bchr12:121707331chr12:121932468ENST0000037706910231059_1105518.01266.0DomainNote=F-box
TgeneKDM2Bchr12:121707331chr12:121932468ENST0000037707110231059_1105549.01337.0DomainNote=F-box
TgeneKDM2Bchr12:121707331chr12:121932468ENST000005429730141059_11050912.0DomainNote=F-box
TgeneKDM2Bchr12:121707331chr12:121932468ENST00000542973014178_3460912.0DomainJmjC
TgeneKDM2Bchr12:121708701chr12:121891147ENST0000037706911231059_1105547.01266.0DomainNote=F-box
TgeneKDM2Bchr12:121708701chr12:121891147ENST0000037707111231059_1105578.01337.0DomainNote=F-box
TgeneKDM2Bchr12:121708701chr12:121891147ENST000005429731141059_11050912.0DomainNote=F-box
TgeneKDM2Bchr12:121708701chr12:121891147ENST00000542973114178_3460912.0DomainJmjC
TgeneKDM2Bchr12:121711859chr12:121932468ENST0000037706910231059_1105518.01266.0DomainNote=F-box
TgeneKDM2Bchr12:121711859chr12:121932468ENST0000037707110231059_1105549.01337.0DomainNote=F-box
TgeneKDM2Bchr12:121711859chr12:121932468ENST000005429730141059_11050912.0DomainNote=F-box
TgeneKDM2Bchr12:121711859chr12:121932468ENST00000542973014178_3460912.0DomainJmjC
TgeneKDM2Bchr12:121682943chr12:121891147ENST0000037706911231093_1120547.01266.0RepeatNote=LRR 1
TgeneKDM2Bchr12:121682943chr12:121891147ENST0000037706911231133_1154547.01266.0RepeatNote=LRR 2
TgeneKDM2Bchr12:121682943chr12:121891147ENST0000037706911231156_1182547.01266.0RepeatNote=LRR 3
TgeneKDM2Bchr12:121682943chr12:121891147ENST0000037706911231222_1247547.01266.0RepeatNote=LRR 4
TgeneKDM2Bchr12:121682943chr12:121891147ENST0000037706911231248_1277547.01266.0RepeatNote=LRR 5
TgeneKDM2Bchr12:121682943chr12:121891147ENST0000037706911231278_1302547.01266.0RepeatNote=LRR 6
TgeneKDM2Bchr12:121682943chr12:121891147ENST0000037706911231303_1336547.01266.0RepeatNote=LRR 7
TgeneKDM2Bchr12:121682943chr12:121891147ENST0000037707111231093_1120578.01337.0RepeatNote=LRR 1
TgeneKDM2Bchr12:121682943chr12:121891147ENST0000037707111231133_1154578.01337.0RepeatNote=LRR 2
TgeneKDM2Bchr12:121682943chr12:121891147ENST0000037707111231156_1182578.01337.0RepeatNote=LRR 3
TgeneKDM2Bchr12:121682943chr12:121891147ENST0000037707111231222_1247578.01337.0RepeatNote=LRR 4
TgeneKDM2Bchr12:121682943chr12:121891147ENST0000037707111231248_1277578.01337.0RepeatNote=LRR 5
TgeneKDM2Bchr12:121682943chr12:121891147ENST0000037707111231278_1302578.01337.0RepeatNote=LRR 6
TgeneKDM2Bchr12:121682943chr12:121891147ENST0000037707111231303_1336578.01337.0RepeatNote=LRR 7
TgeneKDM2Bchr12:121682943chr12:121891147ENST000005429731141093_11200912.0RepeatNote=LRR 1
TgeneKDM2Bchr12:121682943chr12:121891147ENST000005429731141133_11540912.0RepeatNote=LRR 2
TgeneKDM2Bchr12:121682943chr12:121891147ENST000005429731141156_11820912.0RepeatNote=LRR 3
TgeneKDM2Bchr12:121682943chr12:121891147ENST000005429731141222_12470912.0RepeatNote=LRR 4
TgeneKDM2Bchr12:121682943chr12:121891147ENST000005429731141248_12770912.0RepeatNote=LRR 5
TgeneKDM2Bchr12:121682943chr12:121891147ENST000005429731141278_13020912.0RepeatNote=LRR 6
TgeneKDM2Bchr12:121682943chr12:121891147ENST000005429731141303_13360912.0RepeatNote=LRR 7
TgeneKDM2Bchr12:121707331chr12:121932468ENST0000037706910231093_1120518.01266.0RepeatNote=LRR 1
TgeneKDM2Bchr12:121707331chr12:121932468ENST0000037706910231133_1154518.01266.0RepeatNote=LRR 2
TgeneKDM2Bchr12:121707331chr12:121932468ENST0000037706910231156_1182518.01266.0RepeatNote=LRR 3
TgeneKDM2Bchr12:121707331chr12:121932468ENST0000037706910231222_1247518.01266.0RepeatNote=LRR 4
TgeneKDM2Bchr12:121707331chr12:121932468ENST0000037706910231248_1277518.01266.0RepeatNote=LRR 5
TgeneKDM2Bchr12:121707331chr12:121932468ENST0000037706910231278_1302518.01266.0RepeatNote=LRR 6
TgeneKDM2Bchr12:121707331chr12:121932468ENST0000037706910231303_1336518.01266.0RepeatNote=LRR 7
TgeneKDM2Bchr12:121707331chr12:121932468ENST0000037707110231093_1120549.01337.0RepeatNote=LRR 1
TgeneKDM2Bchr12:121707331chr12:121932468ENST0000037707110231133_1154549.01337.0RepeatNote=LRR 2
TgeneKDM2Bchr12:121707331chr12:121932468ENST0000037707110231156_1182549.01337.0RepeatNote=LRR 3
TgeneKDM2Bchr12:121707331chr12:121932468ENST0000037707110231222_1247549.01337.0RepeatNote=LRR 4
TgeneKDM2Bchr12:121707331chr12:121932468ENST0000037707110231248_1277549.01337.0RepeatNote=LRR 5
TgeneKDM2Bchr12:121707331chr12:121932468ENST0000037707110231278_1302549.01337.0RepeatNote=LRR 6
TgeneKDM2Bchr12:121707331chr12:121932468ENST0000037707110231303_1336549.01337.0RepeatNote=LRR 7
TgeneKDM2Bchr12:121707331chr12:121932468ENST000005429730141093_11200912.0RepeatNote=LRR 1
TgeneKDM2Bchr12:121707331chr12:121932468ENST000005429730141133_11540912.0RepeatNote=LRR 2
TgeneKDM2Bchr12:121707331chr12:121932468ENST000005429730141156_11820912.0RepeatNote=LRR 3
TgeneKDM2Bchr12:121707331chr12:121932468ENST000005429730141222_12470912.0RepeatNote=LRR 4
TgeneKDM2Bchr12:121707331chr12:121932468ENST000005429730141248_12770912.0RepeatNote=LRR 5
TgeneKDM2Bchr12:121707331chr12:121932468ENST000005429730141278_13020912.0RepeatNote=LRR 6
TgeneKDM2Bchr12:121707331chr12:121932468ENST000005429730141303_13360912.0RepeatNote=LRR 7
TgeneKDM2Bchr12:121708701chr12:121891147ENST0000037706911231093_1120547.01266.0RepeatNote=LRR 1
TgeneKDM2Bchr12:121708701chr12:121891147ENST0000037706911231133_1154547.01266.0RepeatNote=LRR 2
TgeneKDM2Bchr12:121708701chr12:121891147ENST0000037706911231156_1182547.01266.0RepeatNote=LRR 3
TgeneKDM2Bchr12:121708701chr12:121891147ENST0000037706911231222_1247547.01266.0RepeatNote=LRR 4
TgeneKDM2Bchr12:121708701chr12:121891147ENST0000037706911231248_1277547.01266.0RepeatNote=LRR 5
TgeneKDM2Bchr12:121708701chr12:121891147ENST0000037706911231278_1302547.01266.0RepeatNote=LRR 6
TgeneKDM2Bchr12:121708701chr12:121891147ENST0000037706911231303_1336547.01266.0RepeatNote=LRR 7
TgeneKDM2Bchr12:121708701chr12:121891147ENST0000037707111231093_1120578.01337.0RepeatNote=LRR 1
TgeneKDM2Bchr12:121708701chr12:121891147ENST0000037707111231133_1154578.01337.0RepeatNote=LRR 2
TgeneKDM2Bchr12:121708701chr12:121891147ENST0000037707111231156_1182578.01337.0RepeatNote=LRR 3
TgeneKDM2Bchr12:121708701chr12:121891147ENST0000037707111231222_1247578.01337.0RepeatNote=LRR 4
TgeneKDM2Bchr12:121708701chr12:121891147ENST0000037707111231248_1277578.01337.0RepeatNote=LRR 5
TgeneKDM2Bchr12:121708701chr12:121891147ENST0000037707111231278_1302578.01337.0RepeatNote=LRR 6
TgeneKDM2Bchr12:121708701chr12:121891147ENST0000037707111231303_1336578.01337.0RepeatNote=LRR 7
TgeneKDM2Bchr12:121708701chr12:121891147ENST000005429731141093_11200912.0RepeatNote=LRR 1
TgeneKDM2Bchr12:121708701chr12:121891147ENST000005429731141133_11540912.0RepeatNote=LRR 2
TgeneKDM2Bchr12:121708701chr12:121891147ENST000005429731141156_11820912.0RepeatNote=LRR 3
TgeneKDM2Bchr12:121708701chr12:121891147ENST000005429731141222_12470912.0RepeatNote=LRR 4
TgeneKDM2Bchr12:121708701chr12:121891147ENST000005429731141248_12770912.0RepeatNote=LRR 5
TgeneKDM2Bchr12:121708701chr12:121891147ENST000005429731141278_13020912.0RepeatNote=LRR 6
TgeneKDM2Bchr12:121708701chr12:121891147ENST000005429731141303_13360912.0RepeatNote=LRR 7
TgeneKDM2Bchr12:121711859chr12:121932468ENST0000037706910231093_1120518.01266.0RepeatNote=LRR 1
TgeneKDM2Bchr12:121711859chr12:121932468ENST0000037706910231133_1154518.01266.0RepeatNote=LRR 2
TgeneKDM2Bchr12:121711859chr12:121932468ENST0000037706910231156_1182518.01266.0RepeatNote=LRR 3
TgeneKDM2Bchr12:121711859chr12:121932468ENST0000037706910231222_1247518.01266.0RepeatNote=LRR 4
TgeneKDM2Bchr12:121711859chr12:121932468ENST0000037706910231248_1277518.01266.0RepeatNote=LRR 5
TgeneKDM2Bchr12:121711859chr12:121932468ENST0000037706910231278_1302518.01266.0RepeatNote=LRR 6
TgeneKDM2Bchr12:121711859chr12:121932468ENST0000037706910231303_1336518.01266.0RepeatNote=LRR 7
TgeneKDM2Bchr12:121711859chr12:121932468ENST0000037707110231093_1120549.01337.0RepeatNote=LRR 1
TgeneKDM2Bchr12:121711859chr12:121932468ENST0000037707110231133_1154549.01337.0RepeatNote=LRR 2
TgeneKDM2Bchr12:121711859chr12:121932468ENST0000037707110231156_1182549.01337.0RepeatNote=LRR 3
TgeneKDM2Bchr12:121711859chr12:121932468ENST0000037707110231222_1247549.01337.0RepeatNote=LRR 4
TgeneKDM2Bchr12:121711859chr12:121932468ENST0000037707110231248_1277549.01337.0RepeatNote=LRR 5
TgeneKDM2Bchr12:121711859chr12:121932468ENST0000037707110231278_1302549.01337.0RepeatNote=LRR 6
TgeneKDM2Bchr12:121711859chr12:121932468ENST0000037707110231303_1336549.01337.0RepeatNote=LRR 7
TgeneKDM2Bchr12:121711859chr12:121932468ENST000005429730141093_11200912.0RepeatNote=LRR 1
TgeneKDM2Bchr12:121711859chr12:121932468ENST000005429730141133_11540912.0RepeatNote=LRR 2
TgeneKDM2Bchr12:121711859chr12:121932468ENST000005429730141156_11820912.0RepeatNote=LRR 3
TgeneKDM2Bchr12:121711859chr12:121932468ENST000005429730141222_12470912.0RepeatNote=LRR 4
TgeneKDM2Bchr12:121711859chr12:121932468ENST000005429730141248_12770912.0RepeatNote=LRR 5
TgeneKDM2Bchr12:121711859chr12:121932468ENST000005429730141278_13020912.0RepeatNote=LRR 6
TgeneKDM2Bchr12:121711859chr12:121932468ENST000005429730141303_13360912.0RepeatNote=LRR 7
TgeneKDM2Bchr12:121682943chr12:121891147ENST000003770691123606_652547.01266.0Zinc fingerCXXC-type
TgeneKDM2Bchr12:121682943chr12:121891147ENST000003770691123659_725547.01266.0Zinc fingerPHD-type
TgeneKDM2Bchr12:121682943chr12:121891147ENST000003770711123606_652578.01337.0Zinc fingerCXXC-type
TgeneKDM2Bchr12:121682943chr12:121891147ENST000003770711123659_725578.01337.0Zinc fingerPHD-type
TgeneKDM2Bchr12:121682943chr12:121891147ENST00000542973114606_6520912.0Zinc fingerCXXC-type
TgeneKDM2Bchr12:121682943chr12:121891147ENST00000542973114659_7250912.0Zinc fingerPHD-type
TgeneKDM2Bchr12:121707331chr12:121932468ENST000003770691023606_652518.01266.0Zinc fingerCXXC-type
TgeneKDM2Bchr12:121707331chr12:121932468ENST000003770691023659_725518.01266.0Zinc fingerPHD-type
TgeneKDM2Bchr12:121707331chr12:121932468ENST000003770711023606_652549.01337.0Zinc fingerCXXC-type
TgeneKDM2Bchr12:121707331chr12:121932468ENST000003770711023659_725549.01337.0Zinc fingerPHD-type
TgeneKDM2Bchr12:121707331chr12:121932468ENST00000542973014606_6520912.0Zinc fingerCXXC-type
TgeneKDM2Bchr12:121707331chr12:121932468ENST00000542973014659_7250912.0Zinc fingerPHD-type
TgeneKDM2Bchr12:121708701chr12:121891147ENST000003770691123606_652547.01266.0Zinc fingerCXXC-type
TgeneKDM2Bchr12:121708701chr12:121891147ENST000003770691123659_725547.01266.0Zinc fingerPHD-type
TgeneKDM2Bchr12:121708701chr12:121891147ENST000003770711123606_652578.01337.0Zinc fingerCXXC-type
TgeneKDM2Bchr12:121708701chr12:121891147ENST000003770711123659_725578.01337.0Zinc fingerPHD-type
TgeneKDM2Bchr12:121708701chr12:121891147ENST00000542973114606_6520912.0Zinc fingerCXXC-type
TgeneKDM2Bchr12:121708701chr12:121891147ENST00000542973114659_7250912.0Zinc fingerPHD-type
TgeneKDM2Bchr12:121711859chr12:121932468ENST000003770691023606_652518.01266.0Zinc fingerCXXC-type
TgeneKDM2Bchr12:121711859chr12:121932468ENST000003770691023659_725518.01266.0Zinc fingerPHD-type
TgeneKDM2Bchr12:121711859chr12:121932468ENST000003770711023606_652549.01337.0Zinc fingerCXXC-type
TgeneKDM2Bchr12:121711859chr12:121932468ENST000003770711023659_725549.01337.0Zinc fingerPHD-type
TgeneKDM2Bchr12:121711859chr12:121932468ENST00000542973014606_6520912.0Zinc fingerCXXC-type
TgeneKDM2Bchr12:121711859chr12:121932468ENST00000542973014659_7250912.0Zinc fingerPHD-type

- Not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCAMKK2chr12:121707331chr12:121932468ENST00000324774-417165_446191.0589.0DomainProtein kinase
HgeneCAMKK2chr12:121707331chr12:121932468ENST00000337174-416165_446191.0542.0DomainProtein kinase
HgeneCAMKK2chr12:121707331chr12:121932468ENST00000347034-416165_446191.0546.0DomainProtein kinase
HgeneCAMKK2chr12:121707331chr12:121932468ENST00000392473-417165_446191.0534.0DomainProtein kinase
HgeneCAMKK2chr12:121707331chr12:121932468ENST00000392474-316165_446191.0557.0DomainProtein kinase
HgeneCAMKK2chr12:121707331chr12:121932468ENST00000402834-417165_446191.0589.0DomainProtein kinase
HgeneCAMKK2chr12:121707331chr12:121932468ENST00000404169-417165_446191.0589.0DomainProtein kinase
HgeneCAMKK2chr12:121707331chr12:121932468ENST00000412367-416165_446191.0542.0DomainProtein kinase
HgeneCAMKK2chr12:121707331chr12:121932468ENST00000446440-416165_446191.0491.0DomainProtein kinase
HgeneCAMKK2chr12:121707331chr12:121932468ENST00000538733-415165_446191.0499.0DomainProtein kinase
HgeneCAMKK2chr12:121708701chr12:121891147ENST00000324774-317165_446173.0589.0DomainProtein kinase
HgeneCAMKK2chr12:121708701chr12:121891147ENST00000337174-316165_446173.0542.0DomainProtein kinase
HgeneCAMKK2chr12:121708701chr12:121891147ENST00000347034-316165_446173.0546.0DomainProtein kinase
HgeneCAMKK2chr12:121708701chr12:121891147ENST00000392473-317165_446173.0534.0DomainProtein kinase
HgeneCAMKK2chr12:121708701chr12:121891147ENST00000392474-216165_446173.0557.0DomainProtein kinase
HgeneCAMKK2chr12:121708701chr12:121891147ENST00000402834-317165_446173.0589.0DomainProtein kinase
HgeneCAMKK2chr12:121708701chr12:121891147ENST00000404169-317165_446173.0589.0DomainProtein kinase
HgeneCAMKK2chr12:121708701chr12:121891147ENST00000412367-316165_446173.0542.0DomainProtein kinase
HgeneCAMKK2chr12:121708701chr12:121891147ENST00000446440-316165_446173.0491.0DomainProtein kinase
HgeneCAMKK2chr12:121708701chr12:121891147ENST00000538733-315165_446173.0499.0DomainProtein kinase
HgeneCAMKK2chr12:121711859chr12:121932468ENST00000324774-217165_446157.0589.0DomainProtein kinase
HgeneCAMKK2chr12:121711859chr12:121932468ENST00000337174-216165_446157.0542.0DomainProtein kinase
HgeneCAMKK2chr12:121711859chr12:121932468ENST00000347034-216165_446157.0546.0DomainProtein kinase
HgeneCAMKK2chr12:121711859chr12:121932468ENST00000392473-217165_446157.0534.0DomainProtein kinase
HgeneCAMKK2chr12:121711859chr12:121932468ENST00000392474-116165_446157.0557.0DomainProtein kinase
HgeneCAMKK2chr12:121711859chr12:121932468ENST00000402834-217165_446157.0589.0DomainProtein kinase
HgeneCAMKK2chr12:121711859chr12:121932468ENST00000404169-217165_446157.0589.0DomainProtein kinase
HgeneCAMKK2chr12:121711859chr12:121932468ENST00000412367-216165_446157.0542.0DomainProtein kinase
HgeneCAMKK2chr12:121711859chr12:121932468ENST00000446440-216165_446157.0491.0DomainProtein kinase
HgeneCAMKK2chr12:121711859chr12:121932468ENST00000538733-215165_446157.0499.0DomainProtein kinase
HgeneCAMKK2chr12:121708701chr12:121891147ENST00000324774-317171_179173.0589.0Nucleotide bindingATP
HgeneCAMKK2chr12:121708701chr12:121891147ENST00000337174-316171_179173.0542.0Nucleotide bindingATP
HgeneCAMKK2chr12:121708701chr12:121891147ENST00000347034-316171_179173.0546.0Nucleotide bindingATP
HgeneCAMKK2chr12:121708701chr12:121891147ENST00000392473-317171_179173.0534.0Nucleotide bindingATP
HgeneCAMKK2chr12:121708701chr12:121891147ENST00000392474-216171_179173.0557.0Nucleotide bindingATP
HgeneCAMKK2chr12:121708701chr12:121891147ENST00000402834-317171_179173.0589.0Nucleotide bindingATP
HgeneCAMKK2chr12:121708701chr12:121891147ENST00000404169-317171_179173.0589.0Nucleotide bindingATP
HgeneCAMKK2chr12:121708701chr12:121891147ENST00000412367-316171_179173.0542.0Nucleotide bindingATP
HgeneCAMKK2chr12:121708701chr12:121891147ENST00000446440-316171_179173.0491.0Nucleotide bindingATP
HgeneCAMKK2chr12:121708701chr12:121891147ENST00000538733-315171_179173.0499.0Nucleotide bindingATP
HgeneCAMKK2chr12:121711859chr12:121932468ENST00000324774-217171_179157.0589.0Nucleotide bindingATP
HgeneCAMKK2chr12:121711859chr12:121932468ENST00000337174-216171_179157.0542.0Nucleotide bindingATP
HgeneCAMKK2chr12:121711859chr12:121932468ENST00000347034-216171_179157.0546.0Nucleotide bindingATP
HgeneCAMKK2chr12:121711859chr12:121932468ENST00000392473-217171_179157.0534.0Nucleotide bindingATP
HgeneCAMKK2chr12:121711859chr12:121932468ENST00000392474-116171_179157.0557.0Nucleotide bindingATP
HgeneCAMKK2chr12:121711859chr12:121932468ENST00000402834-217171_179157.0589.0Nucleotide bindingATP
HgeneCAMKK2chr12:121711859chr12:121932468ENST00000404169-217171_179157.0589.0Nucleotide bindingATP
HgeneCAMKK2chr12:121711859chr12:121932468ENST00000412367-216171_179157.0542.0Nucleotide bindingATP
HgeneCAMKK2chr12:121711859chr12:121932468ENST00000446440-216171_179157.0491.0Nucleotide bindingATP
HgeneCAMKK2chr12:121711859chr12:121932468ENST00000538733-215171_179157.0499.0Nucleotide bindingATP
HgeneCAMKK2chr12:121682943chr12:121891147ENST00000347034-1416475_500474.6666666666667546.0RegionCalmodulin-binding
HgeneCAMKK2chr12:121682943chr12:121891147ENST00000446440-1416475_500474.6666666666667491.0RegionCalmodulin-binding
HgeneCAMKK2chr12:121682943chr12:121891147ENST00000538733-1415475_500474.6666666666667499.0RegionCalmodulin-binding
HgeneCAMKK2chr12:121707331chr12:121932468ENST00000324774-417204_226191.0589.0RegionNote=RP domain
HgeneCAMKK2chr12:121707331chr12:121932468ENST00000324774-417472_477191.0589.0RegionAutoinhibitory domain
HgeneCAMKK2chr12:121707331chr12:121932468ENST00000324774-417475_500191.0589.0RegionCalmodulin-binding
HgeneCAMKK2chr12:121707331chr12:121932468ENST00000337174-416204_226191.0542.0RegionNote=RP domain
HgeneCAMKK2chr12:121707331chr12:121932468ENST00000337174-416472_477191.0542.0RegionAutoinhibitory domain
HgeneCAMKK2chr12:121707331chr12:121932468ENST00000337174-416475_500191.0542.0RegionCalmodulin-binding
HgeneCAMKK2chr12:121707331chr12:121932468ENST00000347034-416204_226191.0546.0RegionNote=RP domain
HgeneCAMKK2chr12:121707331chr12:121932468ENST00000347034-416472_477191.0546.0RegionAutoinhibitory domain
HgeneCAMKK2chr12:121707331chr12:121932468ENST00000347034-416475_500191.0546.0RegionCalmodulin-binding
HgeneCAMKK2chr12:121707331chr12:121932468ENST00000392473-417204_226191.0534.0RegionNote=RP domain
HgeneCAMKK2chr12:121707331chr12:121932468ENST00000392473-417472_477191.0534.0RegionAutoinhibitory domain
HgeneCAMKK2chr12:121707331chr12:121932468ENST00000392473-417475_500191.0534.0RegionCalmodulin-binding
HgeneCAMKK2chr12:121707331chr12:121932468ENST00000392474-316204_226191.0557.0RegionNote=RP domain
HgeneCAMKK2chr12:121707331chr12:121932468ENST00000392474-316472_477191.0557.0RegionAutoinhibitory domain
HgeneCAMKK2chr12:121707331chr12:121932468ENST00000392474-316475_500191.0557.0RegionCalmodulin-binding
HgeneCAMKK2chr12:121707331chr12:121932468ENST00000402834-417204_226191.0589.0RegionNote=RP domain
HgeneCAMKK2chr12:121707331chr12:121932468ENST00000402834-417472_477191.0589.0RegionAutoinhibitory domain
HgeneCAMKK2chr12:121707331chr12:121932468ENST00000402834-417475_500191.0589.0RegionCalmodulin-binding
HgeneCAMKK2chr12:121707331chr12:121932468ENST00000404169-417204_226191.0589.0RegionNote=RP domain
HgeneCAMKK2chr12:121707331chr12:121932468ENST00000404169-417472_477191.0589.0RegionAutoinhibitory domain
HgeneCAMKK2chr12:121707331chr12:121932468ENST00000404169-417475_500191.0589.0RegionCalmodulin-binding
HgeneCAMKK2chr12:121707331chr12:121932468ENST00000412367-416204_226191.0542.0RegionNote=RP domain
HgeneCAMKK2chr12:121707331chr12:121932468ENST00000412367-416472_477191.0542.0RegionAutoinhibitory domain
HgeneCAMKK2chr12:121707331chr12:121932468ENST00000412367-416475_500191.0542.0RegionCalmodulin-binding
HgeneCAMKK2chr12:121707331chr12:121932468ENST00000446440-416204_226191.0491.0RegionNote=RP domain
HgeneCAMKK2chr12:121707331chr12:121932468ENST00000446440-416472_477191.0491.0RegionAutoinhibitory domain
HgeneCAMKK2chr12:121707331chr12:121932468ENST00000446440-416475_500191.0491.0RegionCalmodulin-binding
HgeneCAMKK2chr12:121707331chr12:121932468ENST00000538733-415204_226191.0499.0RegionNote=RP domain
HgeneCAMKK2chr12:121707331chr12:121932468ENST00000538733-415472_477191.0499.0RegionAutoinhibitory domain
HgeneCAMKK2chr12:121707331chr12:121932468ENST00000538733-415475_500191.0499.0RegionCalmodulin-binding
HgeneCAMKK2chr12:121708701chr12:121891147ENST00000324774-317204_226173.0589.0RegionNote=RP domain
HgeneCAMKK2chr12:121708701chr12:121891147ENST00000324774-317472_477173.0589.0RegionAutoinhibitory domain
HgeneCAMKK2chr12:121708701chr12:121891147ENST00000324774-317475_500173.0589.0RegionCalmodulin-binding
HgeneCAMKK2chr12:121708701chr12:121891147ENST00000337174-316204_226173.0542.0RegionNote=RP domain
HgeneCAMKK2chr12:121708701chr12:121891147ENST00000337174-316472_477173.0542.0RegionAutoinhibitory domain
HgeneCAMKK2chr12:121708701chr12:121891147ENST00000337174-316475_500173.0542.0RegionCalmodulin-binding
HgeneCAMKK2chr12:121708701chr12:121891147ENST00000347034-316204_226173.0546.0RegionNote=RP domain
HgeneCAMKK2chr12:121708701chr12:121891147ENST00000347034-316472_477173.0546.0RegionAutoinhibitory domain
HgeneCAMKK2chr12:121708701chr12:121891147ENST00000347034-316475_500173.0546.0RegionCalmodulin-binding
HgeneCAMKK2chr12:121708701chr12:121891147ENST00000392473-317204_226173.0534.0RegionNote=RP domain
HgeneCAMKK2chr12:121708701chr12:121891147ENST00000392473-317472_477173.0534.0RegionAutoinhibitory domain
HgeneCAMKK2chr12:121708701chr12:121891147ENST00000392473-317475_500173.0534.0RegionCalmodulin-binding
HgeneCAMKK2chr12:121708701chr12:121891147ENST00000392474-216204_226173.0557.0RegionNote=RP domain
HgeneCAMKK2chr12:121708701chr12:121891147ENST00000392474-216472_477173.0557.0RegionAutoinhibitory domain
HgeneCAMKK2chr12:121708701chr12:121891147ENST00000392474-216475_500173.0557.0RegionCalmodulin-binding
HgeneCAMKK2chr12:121708701chr12:121891147ENST00000402834-317204_226173.0589.0RegionNote=RP domain
HgeneCAMKK2chr12:121708701chr12:121891147ENST00000402834-317472_477173.0589.0RegionAutoinhibitory domain
HgeneCAMKK2chr12:121708701chr12:121891147ENST00000402834-317475_500173.0589.0RegionCalmodulin-binding
HgeneCAMKK2chr12:121708701chr12:121891147ENST00000404169-317204_226173.0589.0RegionNote=RP domain
HgeneCAMKK2chr12:121708701chr12:121891147ENST00000404169-317472_477173.0589.0RegionAutoinhibitory domain
HgeneCAMKK2chr12:121708701chr12:121891147ENST00000404169-317475_500173.0589.0RegionCalmodulin-binding
HgeneCAMKK2chr12:121708701chr12:121891147ENST00000412367-316204_226173.0542.0RegionNote=RP domain
HgeneCAMKK2chr12:121708701chr12:121891147ENST00000412367-316472_477173.0542.0RegionAutoinhibitory domain
HgeneCAMKK2chr12:121708701chr12:121891147ENST00000412367-316475_500173.0542.0RegionCalmodulin-binding
HgeneCAMKK2chr12:121708701chr12:121891147ENST00000446440-316204_226173.0491.0RegionNote=RP domain
HgeneCAMKK2chr12:121708701chr12:121891147ENST00000446440-316472_477173.0491.0RegionAutoinhibitory domain
HgeneCAMKK2chr12:121708701chr12:121891147ENST00000446440-316475_500173.0491.0RegionCalmodulin-binding
HgeneCAMKK2chr12:121708701chr12:121891147ENST00000538733-315204_226173.0499.0RegionNote=RP domain
HgeneCAMKK2chr12:121708701chr12:121891147ENST00000538733-315472_477173.0499.0RegionAutoinhibitory domain
HgeneCAMKK2chr12:121708701chr12:121891147ENST00000538733-315475_500173.0499.0RegionCalmodulin-binding
HgeneCAMKK2chr12:121711859chr12:121932468ENST00000324774-217204_226157.0589.0RegionNote=RP domain
HgeneCAMKK2chr12:121711859chr12:121932468ENST00000324774-217472_477157.0589.0RegionAutoinhibitory domain
HgeneCAMKK2chr12:121711859chr12:121932468ENST00000324774-217475_500157.0589.0RegionCalmodulin-binding
HgeneCAMKK2chr12:121711859chr12:121932468ENST00000337174-216204_226157.0542.0RegionNote=RP domain
HgeneCAMKK2chr12:121711859chr12:121932468ENST00000337174-216472_477157.0542.0RegionAutoinhibitory domain
HgeneCAMKK2chr12:121711859chr12:121932468ENST00000337174-216475_500157.0542.0RegionCalmodulin-binding
HgeneCAMKK2chr12:121711859chr12:121932468ENST00000347034-216204_226157.0546.0RegionNote=RP domain
HgeneCAMKK2chr12:121711859chr12:121932468ENST00000347034-216472_477157.0546.0RegionAutoinhibitory domain
HgeneCAMKK2chr12:121711859chr12:121932468ENST00000347034-216475_500157.0546.0RegionCalmodulin-binding
HgeneCAMKK2chr12:121711859chr12:121932468ENST00000392473-217204_226157.0534.0RegionNote=RP domain
HgeneCAMKK2chr12:121711859chr12:121932468ENST00000392473-217472_477157.0534.0RegionAutoinhibitory domain
HgeneCAMKK2chr12:121711859chr12:121932468ENST00000392473-217475_500157.0534.0RegionCalmodulin-binding
HgeneCAMKK2chr12:121711859chr12:121932468ENST00000392474-116204_226157.0557.0RegionNote=RP domain
HgeneCAMKK2chr12:121711859chr12:121932468ENST00000392474-116472_477157.0557.0RegionAutoinhibitory domain
HgeneCAMKK2chr12:121711859chr12:121932468ENST00000392474-116475_500157.0557.0RegionCalmodulin-binding
HgeneCAMKK2chr12:121711859chr12:121932468ENST00000402834-217204_226157.0589.0RegionNote=RP domain
HgeneCAMKK2chr12:121711859chr12:121932468ENST00000402834-217472_477157.0589.0RegionAutoinhibitory domain
HgeneCAMKK2chr12:121711859chr12:121932468ENST00000402834-217475_500157.0589.0RegionCalmodulin-binding
HgeneCAMKK2chr12:121711859chr12:121932468ENST00000404169-217204_226157.0589.0RegionNote=RP domain
HgeneCAMKK2chr12:121711859chr12:121932468ENST00000404169-217472_477157.0589.0RegionAutoinhibitory domain
HgeneCAMKK2chr12:121711859chr12:121932468ENST00000404169-217475_500157.0589.0RegionCalmodulin-binding
HgeneCAMKK2chr12:121711859chr12:121932468ENST00000412367-216204_226157.0542.0RegionNote=RP domain
HgeneCAMKK2chr12:121711859chr12:121932468ENST00000412367-216472_477157.0542.0RegionAutoinhibitory domain
HgeneCAMKK2chr12:121711859chr12:121932468ENST00000412367-216475_500157.0542.0RegionCalmodulin-binding
HgeneCAMKK2chr12:121711859chr12:121932468ENST00000446440-216204_226157.0491.0RegionNote=RP domain
HgeneCAMKK2chr12:121711859chr12:121932468ENST00000446440-216472_477157.0491.0RegionAutoinhibitory domain
HgeneCAMKK2chr12:121711859chr12:121932468ENST00000446440-216475_500157.0491.0RegionCalmodulin-binding
HgeneCAMKK2chr12:121711859chr12:121932468ENST00000538733-215204_226157.0499.0RegionNote=RP domain
HgeneCAMKK2chr12:121711859chr12:121932468ENST00000538733-215472_477157.0499.0RegionAutoinhibitory domain
HgeneCAMKK2chr12:121711859chr12:121932468ENST00000538733-215475_500157.0499.0RegionCalmodulin-binding
TgeneKDM2Bchr12:121682943chr12:121891147ENST000003770691123409_430547.01266.0Compositional biasNote=Glu-rich
TgeneKDM2Bchr12:121682943chr12:121891147ENST000003770711123409_430578.01337.0Compositional biasNote=Glu-rich
TgeneKDM2Bchr12:121707331chr12:121932468ENST000003770691023409_430518.01266.0Compositional biasNote=Glu-rich
TgeneKDM2Bchr12:121707331chr12:121932468ENST000003770711023409_430549.01337.0Compositional biasNote=Glu-rich
TgeneKDM2Bchr12:121708701chr12:121891147ENST000003770691123409_430547.01266.0Compositional biasNote=Glu-rich
TgeneKDM2Bchr12:121708701chr12:121891147ENST000003770711123409_430578.01337.0Compositional biasNote=Glu-rich
TgeneKDM2Bchr12:121711859chr12:121932468ENST000003770691023409_430518.01266.0Compositional biasNote=Glu-rich
TgeneKDM2Bchr12:121711859chr12:121932468ENST000003770711023409_430549.01337.0Compositional biasNote=Glu-rich
TgeneKDM2Bchr12:121682943chr12:121891147ENST000003770691123178_346547.01266.0DomainJmjC
TgeneKDM2Bchr12:121682943chr12:121891147ENST000003770711123178_346578.01337.0DomainJmjC
TgeneKDM2Bchr12:121707331chr12:121932468ENST000003770691023178_346518.01266.0DomainJmjC
TgeneKDM2Bchr12:121707331chr12:121932468ENST000003770711023178_346549.01337.0DomainJmjC
TgeneKDM2Bchr12:121708701chr12:121891147ENST000003770691123178_346547.01266.0DomainJmjC
TgeneKDM2Bchr12:121708701chr12:121891147ENST000003770711123178_346578.01337.0DomainJmjC
TgeneKDM2Bchr12:121711859chr12:121932468ENST000003770691023178_346518.01266.0DomainJmjC
TgeneKDM2Bchr12:121711859chr12:121932468ENST000003770711023178_346549.01337.0DomainJmjC


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Fusion Protein Structures

check button PDB and CIF files of the predicted fusion proteins
* Here we show the 3D structure of the fusion proteins using Mol*. AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Model confidence is shown from the pLDDT values per residue. pLDDT corresponds to the model’s prediction of its score on the local Distance Difference Test. It is a measure of local accuracy (from AlphfaFold website). To color code individual residues, we transformed individual PDB files into CIF format.
Fusion protein PDB link (fusion AA seq ID in FusionPDB)HgeneHchrHbpHstrandTgeneTchrTbpTstrandAA seqLen(AA seq)
PDB file >>>1774_CAMKK2_121708701_KDM2B_121891147_ranked_0.pdbCAMKK2121708701121708701ENST00000377069KDM2Bchr12121891147-
MEVDSPVNSIPFWLFGRVSETSPGSLDPVGRFREPSRSSFLLFPAQCCYPAGGSNAHLRLQQSGSAAGWECPSVLDEAGACTMSSCVSSQ
PSSNRAAPQDELGGRGSSSSESQKPCEALRGLSSLSIHLGMESFIVVTECEPGCAVDLGLARDRPLEADGQEVPLDTSGSQARPHLSGRK
LSLQERSQGGLAAGGSLDMNGRCICPSLPYSPVSSPQSSPRLPRRPTVESHHVSITGMQDCVQLNQYTLKDEIGKNRAVGRPKGKLGPAS
AVKLAANRTTAGARRRRTRCRKCEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQCIAPVLPHTAVCLVCGEAGKEDTVEEEEGKFNL
MLMECSICNEIIHPGCLKIKESEGVVNDELPNCWECPKCNHAGKTGKQKRGPGFKYASNLPGSLLKEQKMNRDNKEGQEPAKRRSECEEA
PRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEKPQELSGRKRLKPGKEDKLFRKKRRSWKNAEDRMALANKPLRRFKQEPEDELPEAP
PKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKELSRELSKELNHEIQRTENSLANENQQPIKSEPESEGEEPKRPPGIC
ERPHRFSKGLNGTPRELRHQLGPSLRSPPRVISRPPPSVSPPKCIQMERHVIRPPPISPPPDSLPLDDGAAHVMHREVWMAVFSYLSHQD
LCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIRRQPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSS
CPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLDITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLTA
973


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pLDDT score distribution

check button pLDDT score distribution of the predicted wild-type structures of two partner proteins from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.
CAMKK2_pLDDT.png
all structure
all structure
KDM2B_pLDDT.png
all structure
all structure

check button pLDDT score distribution of the predicted fusion protein structures from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.
all structure


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Ramachandran Plot of Fusion Protein Structure


check button Ramachandran plot of the torsional angles - phi (φ)and psi (ψ) - of the residues (amino acids) contained in this fusion protein peptide.
Fusion AA seq ID in FusionPDB and their Ramachandran plots

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Fusion Protein-Protein Interaction


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)
GenePPI interactors


check button Protein-protein interactors based on sequence similarity (STRING)
GeneSTRING network
CAMKK2
KDM2B


check button - Retained interactions in fusion protein (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost interactions due to fusion (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs to CAMKK2-KDM2B


check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

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Related Diseases to CAMKK2-KDM2B


check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource