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Fusion Protein:CBR1-ANKRD17 |
Fusion Protein Summary |
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Fusion partner gene information | Fusion gene name: CBR1-ANKRD17 | FusionPDB ID: 13410 | FusionGDB2.0 ID: 13410 | Hgene | Tgene | Gene symbol | CBR1 | ANKRD17 | Gene ID | 873 | 26057 |
Gene name | carbonyl reductase 1 | ankyrin repeat domain 17 | |
Synonyms | CBR|SDR21C1|hCBR1 | GTAR|MASK2|NY-BR-16 | |
Cytomap | 21q22.12 | 4q13.3 | |
Type of gene | protein-coding | protein-coding | |
Description | carbonyl reductase [NADPH] 115-hydroxyprostaglandin dehydrogenaseNADPH-dependent carbonyl reductase 1carbonyl reductase (NADPH) 1epididymis secretory sperm binding proteinprostaglandin 9-ketoreductaseprostaglandin-E(2) 9-reductaseshort chain dehydr | ankyrin repeat domain-containing protein 17gene trap ankyrin repeat proteinserologically defined breast cancer antigen NY-BR-16 | |
Modification date | 20200313 | 20200313 | |
UniProtAcc | P16152 | O75179 | |
Ensembl transtripts involved in fusion gene | ENST ids | ENST00000466328, ENST00000290349, ENST00000399191, ENST00000439427, ENST00000530908, | ENST00000330838, ENST00000358602, ENST00000509867, ENST00000514252, |
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0) | * DoF score | 3 X 2 X 1=6 | 12 X 18 X 5=1080 |
# samples | 3 | 21 | |
** MAII score | log2(3/6*10)=2.32192809488736 | log2(21/1080*10)=-2.36257007938471 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
Context (manual curation of fusion genes in FusionPDB) | PubMed: CBR1 [Title/Abstract] AND ANKRD17 [Title/Abstract] AND fusion [Title/Abstract] | ||
Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0) | CBR1(37443269)-ANKRD17(73956613), # samples:1 | ||
Anticipated loss of major functional domain due to fusion event. | CBR1-ANKRD17 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. CBR1-ANKRD17 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. CBR1-ANKRD17 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. CBR1-ANKRD17 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. CBR1-ANKRD17 seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF. CBR1-ANKRD17 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF. CBR1-ANKRD17 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF. |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
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Partner | Gene | GO ID | GO term | PubMed ID |
Hgene | CBR1 | GO:0017144 | drug metabolic process | 18449627 |
Hgene | CBR1 | GO:0042373 | vitamin K metabolic process | 18449627 |
Hgene | CBR1 | GO:0055114 | oxidation-reduction process | 19442656 |
Tgene | ANKRD17 | GO:0042742 | defense response to bacterium | 23711367 |
Tgene | ANKRD17 | GO:0043123 | positive regulation of I-kappaB kinase/NF-kappaB signaling | 22328336 |
Tgene | ANKRD17 | GO:0045087 | innate immune response | 23711367 |
Tgene | ANKRD17 | GO:1900245 | positive regulation of MDA-5 signaling pathway | 22328336 |
Tgene | ANKRD17 | GO:1900246 | positive regulation of RIG-I signaling pathway | 22328336 |
![]() * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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![]() * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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Fusion Gene Sample Information |
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![]() * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
ChiTaRS5.0 | N/A | DB034419 | CBR1 | chr21 | 37443269 | + | ANKRD17 | chr4 | 73956613 | - |
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Fusion ORF Analysis |
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Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
ENST00000439427 | CBR1 | chr21 | 37443269 | + | ENST00000358602 | ANKRD17 | chr4 | 73956613 | - | 4938 | 1002 | 625 | 95 | 176 |
ENST00000439427 | CBR1 | chr21 | 37443269 | + | ENST00000509867 | ANKRD17 | chr4 | 73956613 | - | 2628 | 1002 | 625 | 95 | 176 |
ENST00000439427 | CBR1 | chr21 | 37443269 | + | ENST00000330838 | ANKRD17 | chr4 | 73956613 | - | 2628 | 1002 | 625 | 95 | 176 |
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Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
ENST00000439427 | ENST00000358602 | CBR1 | chr21 | 37443269 | + | ANKRD17 | chr4 | 73956613 | - | 0.50837797 | 0.49162203 |
ENST00000439427 | ENST00000509867 | CBR1 | chr21 | 37443269 | + | ANKRD17 | chr4 | 73956613 | - | 0.22774474 | 0.77225524 |
ENST00000439427 | ENST00000330838 | CBR1 | chr21 | 37443269 | + | ANKRD17 | chr4 | 73956613 | - | 0.22774474 | 0.77225524 |
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Fusion Amino Acid Sequences |
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>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP >13410_13410_1_CBR1-ANKRD17_CBR1_chr21_37443269_ENST00000439427_ANKRD17_chr4_73956613_ENST00000330838_length(amino acids)=176AA_BP= MAHISWQEKKHRGQCTCSMERKQEPAGEIPGKQGPNQAPKRRCAVSHQTHLGVLLEGVILCTHLGYQRNLFSSSLQLEYLEGDARVVDQH -------------------------------------------------------------- >13410_13410_2_CBR1-ANKRD17_CBR1_chr21_37443269_ENST00000439427_ANKRD17_chr4_73956613_ENST00000358602_length(amino acids)=176AA_BP= MAHISWQEKKHRGQCTCSMERKQEPAGEIPGKQGPNQAPKRRCAVSHQTHLGVLLEGVILCTHLGYQRNLFSSSLQLEYLEGDARVVDQH -------------------------------------------------------------- >13410_13410_3_CBR1-ANKRD17_CBR1_chr21_37443269_ENST00000439427_ANKRD17_chr4_73956613_ENST00000509867_length(amino acids)=176AA_BP= MAHISWQEKKHRGQCTCSMERKQEPAGEIPGKQGPNQAPKRRCAVSHQTHLGVLLEGVILCTHLGYQRNLFSSSLQLEYLEGDARVVDQH -------------------------------------------------------------- |
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Fusion Protein Functional Features |
![]() Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr21:37443269/chr4:73956613) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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Hgene | Tgene |
CBR1 | ANKRD17 |
FUNCTION: NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol (PubMed:18449627, PubMed:15799708, PubMed:17912391, PubMed:7005231). Can convert prostaglandin E to prostaglandin F2-alpha (By similarity). Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S-nitrosoglutathione (PubMed:18826943, PubMed:17344335). {ECO:0000250|UniProtKB:Q28960, ECO:0000269|PubMed:15799708, ECO:0000269|PubMed:17344335, ECO:0000269|PubMed:17912391, ECO:0000269|PubMed:18449627, ECO:0000269|PubMed:18826943, ECO:0000269|PubMed:7005231}. | FUNCTION: Could play pivotal roles in cell cycle and DNA regulation (PubMed:19150984). Involved in innate immune defense against viruse by positively regulating the viral dsRNA receptors DDX58 and IFIH1 signaling pathways (PubMed:22328336). Involves in NOD2- and NOD1-mediated responses to bacteria suggesting a role in innate antibacterial immune pathways too (PubMed:23711367). Target of enterovirus 71 which is the major etiological agent of HFMD (hand, foot and mouth disease) (PubMed:17276651). Could play a central role for the formation and/or maintenance of the blood vessels of the circulation system (By similarity). {ECO:0000250|UniProtKB:Q99NH0, ECO:0000269|PubMed:17276651, ECO:0000269|PubMed:19150984, ECO:0000269|PubMed:22328336, ECO:0000269|PubMed:23711367}. |
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- Retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000330838 | 0 | 33 | 1442_1526 | 0 | 2353.0 | Coiled coil | Ontology_term=ECO:0000255 | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000358602 | 0 | 34 | 1442_1526 | 0 | 2604.0 | Coiled coil | Ontology_term=ECO:0000255 | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000330838 | 0 | 33 | 1603_1700 | 0 | 2353.0 | Compositional bias | Note=Ser-rich | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000330838 | 0 | 33 | 1950_2106 | 0 | 2353.0 | Compositional bias | Note=Ser-rich | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000330838 | 0 | 33 | 1966_2033 | 0 | 2353.0 | Compositional bias | Note=Thr-rich | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000330838 | 0 | 33 | 858_1008 | 0 | 2353.0 | Compositional bias | Note=Gln-rich | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000330838 | 0 | 33 | 96_110 | 0 | 2353.0 | Compositional bias | Note=Gly-rich | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000358602 | 0 | 34 | 1603_1700 | 0 | 2604.0 | Compositional bias | Note=Ser-rich | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000358602 | 0 | 34 | 1950_2106 | 0 | 2604.0 | Compositional bias | Note=Ser-rich | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000358602 | 0 | 34 | 1966_2033 | 0 | 2604.0 | Compositional bias | Note=Thr-rich | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000358602 | 0 | 34 | 858_1008 | 0 | 2604.0 | Compositional bias | Note=Gln-rich | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000358602 | 0 | 34 | 96_110 | 0 | 2604.0 | Compositional bias | Note=Gly-rich | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000330838 | 0 | 33 | 1725_1789 | 0 | 2353.0 | Domain | KH | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000358602 | 0 | 34 | 1725_1789 | 0 | 2604.0 | Domain | KH | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000330838 | 0 | 33 | 1082_1111 | 0 | 2353.0 | Repeat | Note=ANK 16 | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000330838 | 0 | 33 | 1115_1144 | 0 | 2353.0 | Repeat | Note=ANK 17 | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000330838 | 0 | 33 | 1149_1178 | 0 | 2353.0 | Repeat | Note=ANK 18 | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000330838 | 0 | 33 | 1182_1211 | 0 | 2353.0 | Repeat | Note=ANK 19 | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000330838 | 0 | 33 | 1217_1246 | 0 | 2353.0 | Repeat | Note=ANK 20 | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000330838 | 0 | 33 | 1251_1280 | 0 | 2353.0 | Repeat | Note=ANK 21 | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000330838 | 0 | 33 | 1284_1313 | 0 | 2353.0 | Repeat | Note=ANK 22 | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000330838 | 0 | 33 | 1319_1348 | 0 | 2353.0 | Repeat | Note=ANK 23 | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000330838 | 0 | 33 | 1352_1381 | 0 | 2353.0 | Repeat | Note=ANK 24 | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000330838 | 0 | 33 | 1385_1414 | 0 | 2353.0 | Repeat | Note=ANK 25 | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000330838 | 0 | 33 | 233_262 | 0 | 2353.0 | Repeat | Note=ANK 1 | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000330838 | 0 | 33 | 266_295 | 0 | 2353.0 | Repeat | Note=ANK 2 | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000330838 | 0 | 33 | 300_329 | 0 | 2353.0 | Repeat | Note=ANK 3 | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000330838 | 0 | 33 | 333_362 | 0 | 2353.0 | Repeat | Note=ANK 4 | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000330838 | 0 | 33 | 366_395 | 0 | 2353.0 | Repeat | Note=ANK 5 | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000330838 | 0 | 33 | 400_429 | 0 | 2353.0 | Repeat | Note=ANK 6 | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000330838 | 0 | 33 | 433_462 | 0 | 2353.0 | Repeat | Note=ANK 7 | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000330838 | 0 | 33 | 466_495 | 0 | 2353.0 | Repeat | Note=ANK 8 | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000330838 | 0 | 33 | 499_528 | 0 | 2353.0 | Repeat | Note=ANK 9 | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000330838 | 0 | 33 | 533_562 | 0 | 2353.0 | Repeat | Note=ANK 10 | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000330838 | 0 | 33 | 563_592 | 0 | 2353.0 | Repeat | Note=ANK 11 | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000330838 | 0 | 33 | 596_625 | 0 | 2353.0 | Repeat | Note=ANK 12 | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000330838 | 0 | 33 | 629_658 | 0 | 2353.0 | Repeat | Note=ANK 13 | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000330838 | 0 | 33 | 663_692 | 0 | 2353.0 | Repeat | Note=ANK 14 | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000330838 | 0 | 33 | 696_725 | 0 | 2353.0 | Repeat | Note=ANK 15 | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000358602 | 0 | 34 | 1082_1111 | 0 | 2604.0 | Repeat | Note=ANK 16 | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000358602 | 0 | 34 | 1115_1144 | 0 | 2604.0 | Repeat | Note=ANK 17 | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000358602 | 0 | 34 | 1149_1178 | 0 | 2604.0 | Repeat | Note=ANK 18 | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000358602 | 0 | 34 | 1182_1211 | 0 | 2604.0 | Repeat | Note=ANK 19 | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000358602 | 0 | 34 | 1217_1246 | 0 | 2604.0 | Repeat | Note=ANK 20 | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000358602 | 0 | 34 | 1251_1280 | 0 | 2604.0 | Repeat | Note=ANK 21 | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000358602 | 0 | 34 | 1284_1313 | 0 | 2604.0 | Repeat | Note=ANK 22 | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000358602 | 0 | 34 | 1319_1348 | 0 | 2604.0 | Repeat | Note=ANK 23 | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000358602 | 0 | 34 | 1352_1381 | 0 | 2604.0 | Repeat | Note=ANK 24 | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000358602 | 0 | 34 | 1385_1414 | 0 | 2604.0 | Repeat | Note=ANK 25 | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000358602 | 0 | 34 | 233_262 | 0 | 2604.0 | Repeat | Note=ANK 1 | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000358602 | 0 | 34 | 266_295 | 0 | 2604.0 | Repeat | Note=ANK 2 | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000358602 | 0 | 34 | 300_329 | 0 | 2604.0 | Repeat | Note=ANK 3 | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000358602 | 0 | 34 | 333_362 | 0 | 2604.0 | Repeat | Note=ANK 4 | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000358602 | 0 | 34 | 366_395 | 0 | 2604.0 | Repeat | Note=ANK 5 | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000358602 | 0 | 34 | 400_429 | 0 | 2604.0 | Repeat | Note=ANK 6 | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000358602 | 0 | 34 | 433_462 | 0 | 2604.0 | Repeat | Note=ANK 7 | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000358602 | 0 | 34 | 466_495 | 0 | 2604.0 | Repeat | Note=ANK 8 | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000358602 | 0 | 34 | 499_528 | 0 | 2604.0 | Repeat | Note=ANK 9 | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000358602 | 0 | 34 | 533_562 | 0 | 2604.0 | Repeat | Note=ANK 10 | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000358602 | 0 | 34 | 563_592 | 0 | 2604.0 | Repeat | Note=ANK 11 | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000358602 | 0 | 34 | 596_625 | 0 | 2604.0 | Repeat | Note=ANK 12 | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000358602 | 0 | 34 | 629_658 | 0 | 2604.0 | Repeat | Note=ANK 13 | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000358602 | 0 | 34 | 663_692 | 0 | 2604.0 | Repeat | Note=ANK 14 | |
Tgene | ANKRD17 | chr21:37443269 | chr4:73956613 | ENST00000358602 | 0 | 34 | 696_725 | 0 | 2604.0 | Repeat | Note=ANK 15 |
- Not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
Hgene | CBR1 | chr21:37443269 | chr4:73956613 | ENST00000290349 | + | 1 | 3 | 10_34 | 0 | 278.0 | Nucleotide binding | NADP |
Hgene | CBR1 | chr21:37443269 | chr4:73956613 | ENST00000290349 | + | 1 | 3 | 194_198 | 0 | 278.0 | Nucleotide binding | NADP |
Hgene | CBR1 | chr21:37443269 | chr4:73956613 | ENST00000290349 | + | 1 | 3 | 231_233 | 0 | 278.0 | Nucleotide binding | NADP |
Hgene | CBR1 | chr21:37443269 | chr4:73956613 | ENST00000290349 | + | 1 | 3 | 63_64 | 0 | 278.0 | Nucleotide binding | NADP |
Hgene | CBR1 | chr21:37443269 | chr4:73956613 | ENST00000290349 | + | 1 | 3 | 193_194 | 0 | 278.0 | Region | Note=Glutathione binding |
Hgene | CBR1 | chr21:37443269 | chr4:73956613 | ENST00000290349 | + | 1 | 3 | 95_97 | 0 | 278.0 | Region | Note=Glutathione binding |
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Fusion Protein-Protein Interaction |
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Gene | PPI interactors |
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Gene | STRING network |
CBR1 | |
ANKRD17 |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs to CBR1-ANKRD17 |
![]() (Manual curation of PubMed, 04-30-2022 + MyCancerGenome) |
Hgene | Tgene | Drug | Source | PMID |
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Related Diseases to CBR1-ANKRD17 |
![]() (Manual curation of PubMed, 04-30-2022 + MyCancerGenome) |
Hgene | Tgene | Disease | Source | PMID |
![]() (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |