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	Fusion Gene Summary
	Fusion Gene Sample Information
	Fusion ORF Analysis
	Fusion Amino Acid Sequences
	Fusion Protein Functional Features
	Fusion Protein-Protein Interaction
	Related drugs with this fusion protein
	Related disease with this fusion protein

Fusion Protein:ACSL5-VTI1A

Fusion Protein Summary

Fusion gene summary

Fusion partner gene information	Fusion gene name: ACSL5-VTI1A
	FusionPDB ID: 1518
	FusionGDB2.0 ID: 1518
		Hgene	Tgene
	Gene symbol	ACSL5	VTI1A
	Gene ID	51703	143187
	Gene name	acyl-CoA synthetase long chain family member 5	vesicle transport through interaction with t-SNAREs 1A
	Synonyms	ACS2\|ACS5\|FACL5	MMDS3\|MVti1\|VTI1RP2\|Vti1-rp2
	Cytomap	10q25.2	10q25.2
	Type of gene	protein-coding	protein-coding
	Description	long-chain-fatty-acid--CoA ligase 5FACL5 for fatty acid coenzyme A ligase 5LACS 5arachidonate--CoA ligasefatty acid coenzyme A ligase 5fatty-acid-Coenzyme A ligase, long-chain 5long-chain acyl-CoA synthetase 5long-chain fatty acid coenzyme A ligase	vesicle transport through interaction with t-SNAREs homolog 1ASNARE Vti1a-beta proteinvesicle transport v-SNARE protein Vti1-like 2
	Modification date	20200313	20200313
	UniProtAcc	Q9ULC5	Q96AJ9
Ensembl transtripts involved in fusion gene	ENST ids	ENST00000479936, ENST00000354273, ENST00000354655, ENST00000356116, ENST00000393081, ENST00000433418, ENST00000369410,	ENST00000393077, ENST00000432306, ENST00000483122,
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)	* DoF score	6 X 6 X 5=180	17 X 15 X 10=2550
	# samples	6	24
	** MAII score	log2(6/180*10)=-1.58496250072116 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(24/2550*10)=-3.4093909361377 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)	PubMed: ACSL5 [Title/Abstract] AND VTI1A [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)	VTI1A(114224416)-ACSL5(114154676), # samples:2 ACSL5(114164564)-VTI1A(114286845), # samples:1
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	ACSL5	GO:0001676	long-chain fatty acid metabolic process	24269233
Tgene	VTI1A	GO:0042147	retrograde transport, endosome to Golgi	15215310\|18195106

Fusion gene breakpoints across ACSL5 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across VTI1A (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

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Fusion Gene Sample Information

Fusion gene information from FusionGDB2.0.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	STAD	TCGA-HU-A4GP	ACSL5	chr10	114164564	+	VTI1A	chr10	114286845	+

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Fusion ORF Analysis

Fusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000354655	ACSL5	chr10	114164564	+	ENST00000432306	VTI1A	chr10	114286845	+	2071	713	254	1060	268
ENST00000354655	ACSL5	chr10	114164564	+	ENST00000393077	VTI1A	chr10	114286845	+	4464	713	254	1102	282
ENST00000393081	ACSL5	chr10	114164564	+	ENST00000432306	VTI1A	chr10	114286845	+	2097	739	280	1086	268
ENST00000393081	ACSL5	chr10	114164564	+	ENST00000393077	VTI1A	chr10	114286845	+	4490	739	280	1128	282
ENST00000433418	ACSL5	chr10	114164564	+	ENST00000432306	VTI1A	chr10	114286845	+	2070	712	49	1059	336
ENST00000433418	ACSL5	chr10	114164564	+	ENST00000393077	VTI1A	chr10	114286845	+	4463	712	49	1101	350
ENST00000356116	ACSL5	chr10	114164564	+	ENST00000432306	VTI1A	chr10	114286845	+	2070	712	49	1059	336
ENST00000356116	ACSL5	chr10	114164564	+	ENST00000393077	VTI1A	chr10	114286845	+	4463	712	49	1101	350
ENST00000354273	ACSL5	chr10	114164564	+	ENST00000432306	VTI1A	chr10	114286845	+	2069	711	48	1058	336
ENST00000354273	ACSL5	chr10	114164564	+	ENST00000393077	VTI1A	chr10	114286845	+	4462	711	48	1100	350

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000354655	ENST00000432306	ACSL5	chr10	114164564	+	VTI1A	chr10	114286845	+	0.000553391	0.9994466
ENST00000354655	ENST00000393077	ACSL5	chr10	114164564	+	VTI1A	chr10	114286845	+	0.00033705	0.999663
ENST00000393081	ENST00000432306	ACSL5	chr10	114164564	+	VTI1A	chr10	114286845	+	0.000723291	0.9992767
ENST00000393081	ENST00000393077	ACSL5	chr10	114164564	+	VTI1A	chr10	114286845	+	0.000469505	0.99953055
ENST00000433418	ENST00000432306	ACSL5	chr10	114164564	+	VTI1A	chr10	114286845	+	0.001736645	0.9982634
ENST00000433418	ENST00000393077	ACSL5	chr10	114164564	+	VTI1A	chr10	114286845	+	0.001029704	0.99897027
ENST00000356116	ENST00000432306	ACSL5	chr10	114164564	+	VTI1A	chr10	114286845	+	0.001736645	0.9982634
ENST00000356116	ENST00000393077	ACSL5	chr10	114164564	+	VTI1A	chr10	114286845	+	0.001029704	0.99897027
ENST00000354273	ENST00000432306	ACSL5	chr10	114164564	+	VTI1A	chr10	114286845	+	0.001749182	0.9982508
ENST00000354273	ENST00000393077	ACSL5	chr10	114164564	+	VTI1A	chr10	114286845	+	0.001035217	0.9989648

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Fusion Amino Acid Sequences

For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>1518_1518_1_ACSL5-VTI1A_ACSL5_chr10_114164564_ENST00000354273_VTI1A_chr10_114286845_ENST00000393077_length(amino acids)=350AA_BP=1
MTRDSSEQGRTGDTLGRPSACMDALKPPCLWRNHERGKKDRDSCGRKNSEPGSPHSLEALRDAAPSQGLNFLLLFTKMLFIFNFLFSPLP
TPALICILTFGAAIFLWLITRPQPVLPLLDLNNQSVGIEGGARKGVSQKNNDLTSCCFSDAKTMYEVFQRGLAVSDNGPCLGYRKPNQPY
RWLSYKQVSDRAEYLGSCLLHKGYKSSPDQFVGIFAQNRPEKRSRIAYSDEVRNELLGDDGNSSENQRAHLLDNTERLERSSRRLEAGYQ

--------------------------------------------------------------

>1518_1518_2_ACSL5-VTI1A_ACSL5_chr10_114164564_ENST00000354273_VTI1A_chr10_114286845_ENST00000432306_length(amino acids)=336AA_BP=1
MTRDSSEQGRTGDTLGRPSACMDALKPPCLWRNHERGKKDRDSCGRKNSEPGSPHSLEALRDAAPSQGLNFLLLFTKMLFIFNFLFSPLP
TPALICILTFGAAIFLWLITRPQPVLPLLDLNNQSVGIEGGARKGVSQKNNDLTSCCFSDAKTMYEVFQRGLAVSDNGPCLGYRKPNQPY
RWLSYKQVSDRAEYLGSCLLHKGYKSSPDQFVGIFAQNRPEKRSRIAYSDEVRNELLGDDGNSSENQRAHLLDNTERLERSSRRLEAGYQ

--------------------------------------------------------------

>1518_1518_3_ACSL5-VTI1A_ACSL5_chr10_114164564_ENST00000354655_VTI1A_chr10_114286845_ENST00000393077_length(amino acids)=282AA_BP=1
MNFLLLFTKMLFIFNFLFSPLPTPALICILTFGAAIFLWLITRPQPVLPLLDLNNQSVGIEGGARKGVSQKNNDLTSCCFSDAKTMYEVF
QRGLAVSDNGPCLGYRKPNQPYRWLSYKQVSDRAEYLGSCLLHKGYKSSPDQFVGIFAQNRPEKRSRIAYSDEVRNELLGDDGNSSENQR
AHLLDNTERLERSSRRLEAGYQIAVETEQIGQEMLENLSHDREKIQRARERLRETDANLGKSSRILTGMLRRIIQNRILLVILGIIVVIT

--------------------------------------------------------------

>1518_1518_4_ACSL5-VTI1A_ACSL5_chr10_114164564_ENST00000354655_VTI1A_chr10_114286845_ENST00000432306_length(amino acids)=268AA_BP=1
MNFLLLFTKMLFIFNFLFSPLPTPALICILTFGAAIFLWLITRPQPVLPLLDLNNQSVGIEGGARKGVSQKNNDLTSCCFSDAKTMYEVF
QRGLAVSDNGPCLGYRKPNQPYRWLSYKQVSDRAEYLGSCLLHKGYKSSPDQFVGIFAQNRPEKRSRIAYSDEVRNELLGDDGNSSENQR

--------------------------------------------------------------

>1518_1518_5_ACSL5-VTI1A_ACSL5_chr10_114164564_ENST00000356116_VTI1A_chr10_114286845_ENST00000393077_length(amino acids)=350AA_BP=1
MTRDSSEQGRTGDTLGRPSACMDALKPPCLWRNHERGKKDRDSCGRKNSEPGSPHSLEALRDAAPSQGLNFLLLFTKMLFIFNFLFSPLP
TPALICILTFGAAIFLWLITRPQPVLPLLDLNNQSVGIEGGARKGVSQKNNDLTSCCFSDAKTMYEVFQRGLAVSDNGPCLGYRKPNQPY
RWLSYKQVSDRAEYLGSCLLHKGYKSSPDQFVGIFAQNRPEKRSRIAYSDEVRNELLGDDGNSSENQRAHLLDNTERLERSSRRLEAGYQ

--------------------------------------------------------------

>1518_1518_6_ACSL5-VTI1A_ACSL5_chr10_114164564_ENST00000356116_VTI1A_chr10_114286845_ENST00000432306_length(amino acids)=336AA_BP=1
MTRDSSEQGRTGDTLGRPSACMDALKPPCLWRNHERGKKDRDSCGRKNSEPGSPHSLEALRDAAPSQGLNFLLLFTKMLFIFNFLFSPLP
TPALICILTFGAAIFLWLITRPQPVLPLLDLNNQSVGIEGGARKGVSQKNNDLTSCCFSDAKTMYEVFQRGLAVSDNGPCLGYRKPNQPY
RWLSYKQVSDRAEYLGSCLLHKGYKSSPDQFVGIFAQNRPEKRSRIAYSDEVRNELLGDDGNSSENQRAHLLDNTERLERSSRRLEAGYQ

--------------------------------------------------------------

>1518_1518_7_ACSL5-VTI1A_ACSL5_chr10_114164564_ENST00000393081_VTI1A_chr10_114286845_ENST00000393077_length(amino acids)=282AA_BP=1
MNFLLLFTKMLFIFNFLFSPLPTPALICILTFGAAIFLWLITRPQPVLPLLDLNNQSVGIEGGARKGVSQKNNDLTSCCFSDAKTMYEVF
QRGLAVSDNGPCLGYRKPNQPYRWLSYKQVSDRAEYLGSCLLHKGYKSSPDQFVGIFAQNRPEKRSRIAYSDEVRNELLGDDGNSSENQR
AHLLDNTERLERSSRRLEAGYQIAVETEQIGQEMLENLSHDREKIQRARERLRETDANLGKSSRILTGMLRRIIQNRILLVILGIIVVIT

--------------------------------------------------------------

>1518_1518_8_ACSL5-VTI1A_ACSL5_chr10_114164564_ENST00000393081_VTI1A_chr10_114286845_ENST00000432306_length(amino acids)=268AA_BP=1
MNFLLLFTKMLFIFNFLFSPLPTPALICILTFGAAIFLWLITRPQPVLPLLDLNNQSVGIEGGARKGVSQKNNDLTSCCFSDAKTMYEVF
QRGLAVSDNGPCLGYRKPNQPYRWLSYKQVSDRAEYLGSCLLHKGYKSSPDQFVGIFAQNRPEKRSRIAYSDEVRNELLGDDGNSSENQR

--------------------------------------------------------------

>1518_1518_9_ACSL5-VTI1A_ACSL5_chr10_114164564_ENST00000433418_VTI1A_chr10_114286845_ENST00000393077_length(amino acids)=350AA_BP=1
MTRDSSEQGRTGDTLGRPSACMDALKPPCLWRNHERGKKDRDSCGRKNSEPGSPHSLEALRDAAPSQGLNFLLLFTKMLFIFNFLFSPLP
TPALICILTFGAAIFLWLITRPQPVLPLLDLNNQSVGIEGGARKGVSQKNNDLTSCCFSDAKTMYEVFQRGLAVSDNGPCLGYRKPNQPY
RWLSYKQVSDRAEYLGSCLLHKGYKSSPDQFVGIFAQNRPEKRSRIAYSDEVRNELLGDDGNSSENQRAHLLDNTERLERSSRRLEAGYQ

--------------------------------------------------------------

>1518_1518_10_ACSL5-VTI1A_ACSL5_chr10_114164564_ENST00000433418_VTI1A_chr10_114286845_ENST00000432306_length(amino acids)=336AA_BP=1
MTRDSSEQGRTGDTLGRPSACMDALKPPCLWRNHERGKKDRDSCGRKNSEPGSPHSLEALRDAAPSQGLNFLLLFTKMLFIFNFLFSPLP
TPALICILTFGAAIFLWLITRPQPVLPLLDLNNQSVGIEGGARKGVSQKNNDLTSCCFSDAKTMYEVFQRGLAVSDNGPCLGYRKPNQPY
RWLSYKQVSDRAEYLGSCLLHKGYKSSPDQFVGIFAQNRPEKRSRIAYSDEVRNELLGDDGNSSENQRAHLLDNTERLERSSRRLEAGYQ

--------------------------------------------------------------

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Fusion Protein Functional Features

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr10:114224416/chr10:114154676)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
ACSL5 Q9ULC5	VTI1A Q96AJ9
FUNCTION: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation (PubMed:17681178, PubMed:24269233, PubMed:22633490). ACSL5 may activate fatty acids from exogenous sources for the synthesis of triacylglycerol destined for intracellular storage (By similarity). Utilizes a wide range of saturated fatty acids with a preference for C16-C18 unsaturated fatty acids (By similarity). It was suggested that it may also stimulate fatty acid oxidation (By similarity). At the villus tip of the crypt-villus axis of the small intestine may sensitize epithelial cells to apoptosis specifically triggered by the death ligand TRAIL. May have a role in the survival of glioma cells. {ECO:0000250, ECO:0000269\|PubMed:17681178, ECO:0000269\|PubMed:18806831, ECO:0000269\|PubMed:19459852, ECO:0000269\|PubMed:22633490, ECO:0000269\|PubMed:24269233}.	FUNCTION: V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. Involved in vesicular transport from the late endosomes to the trans-Golgi network. Along with VAMP7, involved in an non-conventional RAB1-dependent traffic route to the cell surface used by KCNIP1 and KCND2. May be involved in increased cytokine secretion associated with cellular senescence. {ECO:0000269\|PubMed:18195106, ECO:0000269\|PubMed:19138172}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page
* Minus value of BPloci means that the break pointn is located before the CDS.

- Retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

ACSL5

chr10:114164564

chr10:114286845

ENST00000354273

12_32

144.0

684.0

Transmembrane

Helical%3B Signal-anchor for type III membrane protein

Hgene

ACSL5

chr10:114164564

chr10:114286845

ENST00000354655

12_32

144.0

684.0

Transmembrane

Helical%3B Signal-anchor for type III membrane protein

Hgene

ACSL5

chr10:114164564

chr10:114286845

ENST00000356116

12_32

200.0

740.0

Transmembrane

Helical%3B Signal-anchor for type III membrane protein

Hgene

ACSL5

chr10:114164564

chr10:114286845

ENST00000393081

12_32

144.0

684.0

Transmembrane

Helical%3B Signal-anchor for type III membrane protein

Hgene

ACSL5

chr10:114164564

chr10:114286845

ENST00000433418

12_32

144.0

660.0

Transmembrane

Helical%3B Signal-anchor for type III membrane protein

Tgene

VTI1A

chr10:114164564

chr10:114286845

ENST00000393077

112_178

88.0

218.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

VTI1A

chr10:114164564

chr10:114286845

ENST00000432306

112_178

88.0

204.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

VTI1A

chr10:114164564

chr10:114286845

ENST00000393077

214_217

88.0

218.0

Topological domain

Extracellular

Tgene

VTI1A

chr10:114164564

chr10:114286845

ENST00000432306

214_217

88.0

204.0

Topological domain

Extracellular

Tgene

VTI1A

chr10:114164564

chr10:114286845

ENST00000393077

193_213

88.0

218.0

Transmembrane

Helical

Tgene

VTI1A

chr10:114164564

chr10:114286845

ENST00000432306

193_213

88.0

204.0

Transmembrane

Helical

- Not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

ACSL5

chr10:114164564

chr10:114286845

ENST00000354273

33_683

144.0

684.0

Topological domain

Cytoplasmic

Hgene

ACSL5

chr10:114164564

chr10:114286845

ENST00000354655

33_683

144.0

684.0

Topological domain

Cytoplasmic

Hgene

ACSL5

chr10:114164564

chr10:114286845

ENST00000356116

33_683

200.0

740.0

Topological domain

Cytoplasmic

Hgene

ACSL5

chr10:114164564

chr10:114286845

ENST00000393081

33_683

144.0

684.0

Topological domain

Cytoplasmic

Hgene

ACSL5

chr10:114164564

chr10:114286845

ENST00000433418

33_683

144.0

660.0

Topological domain

Cytoplasmic

Tgene

VTI1A

chr10:114164564

chr10:114286845

ENST00000393077

31_92

88.0

218.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

VTI1A

chr10:114164564

chr10:114286845

ENST00000432306

31_92

88.0

204.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

VTI1A

chr10:114164564

chr10:114286845

ENST00000393077

1_192

88.0

218.0

Topological domain

Cytoplasmic

Tgene

VTI1A

chr10:114164564

chr10:114286845

ENST00000432306

1_192

88.0

204.0

Topological domain

Cytoplasmic

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Fusion Protein-Protein Interaction

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)

Gene	PPI interactors
ACSL5	CREB3, KIF11, FAM136A, COQ9, FBXO7, RNF4, RAB7A, SLC7A14, SLC35C2, AQP6, SLC10A1, PEX12, SLC16A7, TMEM14B, EPT1, FAM134C, SLC10A6, EBAG9, CAV2, ELK1, PAK1, PEBP1, PRKCB, PRKD1, SH2D3C, PDS5A, WDR5,
VTI1A	VAMP4, VAMP3, STX7, STX8, VAMP8, env, TMBIM6, STX6, STX12, CLEC12A, Snap29, HAUS1, HNRNPL, RNF4, BET1, APEX1, NAPA, VAMP5, ORF7b, ARF6, B3GAT1, LAMP2, LAMP3, LAMTOR1, MARCKS, RAB2A, RAB4A, RAB5A, RAB5C, RAB9A, EDEM1, TRPC4AP, TMEM74, ZDHHC12, SEC22B, SMPD1, TMEM9, NAPG, TMEM9B, GPRC5B, B4GALT5, TMEM171, ASPH, SLC39A4, VPS45, SNAP29, HLA-C, STX11, STX18,

Protein-protein interactors based on sequence similarity (STRING)

Gene	STRING network
ACSL5
VTI1A

- Retained interactions in fusion protein (protein functional feature from UniProt).

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost interactions due to fusion (protein functional feature from UniProt).

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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Related Drugs to ACSL5-VTI1A

Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene

Tgene

Drug

Source

PMID

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Related Diseases to ACSL5-VTI1A

Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene

Tgene

Disease

Source

PMID

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner	Gene	Disease ID	Disease name	# pubmeds	Source
Hgene	ACSL5	C0003865	Arthritis, Adjuvant-Induced	1	CTD_human
Hgene	ACSL5	C0971858	Arthritis, Collagen-Induced	1	CTD_human
Hgene	ACSL5	C0993582	Arthritis, Experimental	1	CTD_human
Tgene	VTI1A	C0001418	Adenocarcinoma	1	CTD_human
Tgene	VTI1A	C0009402	Colorectal Carcinoma	1	CTD_human
Tgene	VTI1A	C0009404	Colorectal Neoplasms	1	CTD_human
Tgene	VTI1A	C0205641	Adenocarcinoma, Basal Cell	1	CTD_human
Tgene	VTI1A	C0205642	Adenocarcinoma, Oxyphilic	1	CTD_human
Tgene	VTI1A	C0205643	Carcinoma, Cribriform	1	CTD_human
Tgene	VTI1A	C0205644	Carcinoma, Granular Cell	1	CTD_human
Tgene	VTI1A	C0205645	Adenocarcinoma, Tubular	1	CTD_human