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Center for Computational Systems Medicine level1
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Fusion Gene Summary

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Fusion Gene Sample Information

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Fusion ORF Analysis

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Fusion Amino Acid Sequences

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Fusion Protein Functional Features

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Fusion Protein-Protein Interaction

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Related drugs with this fusion protein

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Related disease with this fusion protein

Fusion Protein:CHST11-MAP4

Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: CHST11-MAP4
FusionPDB ID: 16688
FusionGDB2.0 ID: 16688
HgeneTgene
Gene symbol

CHST11

MAP4

Gene ID

50515

4134

Gene namecarbohydrate sulfotransferase 11microtubule associated protein 4
SynonymsC4ST|C4ST-1|C4ST1|HSA269537|OCBMD-
Cytomap

12q23.3

3p21.31

Type of geneprotein-codingprotein-coding
Descriptioncarbohydrate sulfotransferase 11C4S-1IgH/CHST11 fusioncarbohydrate (chondroitin 4) sulfotransferase 11chondroitin 4-O-sulfotransferase 1microtubule-associated protein 4MAP-4
Modification date2020031320200313
UniProtAcc

Q9NPF2

Q9Y4K4

Ensembl transtripts involved in fusion geneENST idsENST00000303694, ENST00000547956, 
ENST00000546689, ENST00000549260, 
ENST00000550711, 		ENST00000441748, 
ENST00000462206, ENST00000264724, 
ENST00000420772, ENST00000434267, 
ENST00000439356, ENST00000360240, 
ENST00000383737, ENST00000395734, 
ENST00000426837, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score13 X 8 X 6=62419 X 21 X 12=4788
# samples 1535
** MAII scorelog2(15/624*10)=-2.05658352836637
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(35/4788*10)=-3.77399632511117
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)

PubMed: CHST11 [Title/Abstract] AND MAP4 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)CHST11(104851307)-MAP4(47919013), # samples:1
Anticipated loss of major functional domain due to fusion event.CHST11-MAP4 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CHST11-MAP4 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CHST11-MAP4 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
CHST11-MAP4 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCHST11

GO:0030206

chondroitin sulfate biosynthetic process

11056388


check buttonFusion gene breakpoints across CHST11 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across MAP4 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


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Fusion Gene Sample Information

check buttonFusion gene information from FusionGDB2.0.
check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-CD-5800CHST11chr12

104851307

+MAP4chr3

47919013

-


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Fusion ORF Analysis


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000547956CHST11chr12104851307+ENST00000383737MAP4chr347919013-4155562151814599
ENST00000547956CHST11chr12104851307+ENST00000395734MAP4chr347919013-4067562151970651
ENST00000547956CHST11chr12104851307+ENST00000426837MAP4chr347919013-3960562152021668
ENST00000547956CHST11chr12104851307+ENST00000360240MAP4chr347919013-3186562152021668
ENST00000303694CHST11chr12104851307+ENST00000383737MAP4chr347919013-4150557101809599
ENST00000303694CHST11chr12104851307+ENST00000395734MAP4chr347919013-4062557101965651
ENST00000303694CHST11chr12104851307+ENST00000426837MAP4chr347919013-3955557102016668
ENST00000303694CHST11chr12104851307+ENST00000360240MAP4chr347919013-3181557102016668

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000547956ENST00000383737CHST11chr12104851307+MAP4chr347919013-0.0052495110.99475056
ENST00000547956ENST00000395734CHST11chr12104851307+MAP4chr347919013-0.0038020630.9961979
ENST00000547956ENST00000426837CHST11chr12104851307+MAP4chr347919013-0.0046994580.99530053
ENST00000547956ENST00000360240CHST11chr12104851307+MAP4chr347919013-0.0046543370.99534565
ENST00000303694ENST00000383737CHST11chr12104851307+MAP4chr347919013-0.0052826570.9947174
ENST00000303694ENST00000395734CHST11chr12104851307+MAP4chr347919013-0.0038244870.9961755
ENST00000303694ENST00000426837CHST11chr12104851307+MAP4chr347919013-0.0047279140.9952721
ENST00000303694ENST00000360240CHST11chr12104851307+MAP4chr347919013-0.0047050510.995295

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Fusion Amino Acid Sequences


check button For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>16688_16688_1_CHST11-MAP4_CHST11_chr12_104851307_ENST00000303694_MAP4_chr3_47919013_ENST00000360240_length(amino acids)=668AA_BP=182
MERNEVAFGEKGEGPSDSHSGQRSGSGGGTTITARTPAARPATRQRRPPAGSEEAAERRGGGAGARSQRVHASQHFQTNSGTFHTPARAG
GSESGREATPILPLSLAQLCPAPPGLRSARRGPCSCAPGALPGHPGPRSQDKAMKPALLEVMRMNRICRMVLATCLGSFILVIFYFQSML
HPGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPK
RPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPA
EVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKN
VRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQ
IQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLCPGPPAGEEPAISEAAP

--------------------------------------------------------------

>16688_16688_2_CHST11-MAP4_CHST11_chr12_104851307_ENST00000303694_MAP4_chr3_47919013_ENST00000383737_length(amino acids)=599AA_BP=182
MERNEVAFGEKGEGPSDSHSGQRSGSGGGTTITARTPAARPATRQRRPPAGSEEAAERRGGGAGARSQRVHASQHFQTNSGTFHTPARAG
GSESGREATPILPLSLAQLCPAPPGLRSARRGPCSCAPGALPGHPGPRSQDKAMKPALLEVMRMNRICRMVLATCLGSFILVIFYFQSML
HPGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPK
RPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPA
EVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKN
VRSKVGSTENIKHQPGGGRVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGS

--------------------------------------------------------------

>16688_16688_3_CHST11-MAP4_CHST11_chr12_104851307_ENST00000303694_MAP4_chr3_47919013_ENST00000395734_length(amino acids)=651AA_BP=182
MERNEVAFGEKGEGPSDSHSGQRSGSGGGTTITARTPAARPATRQRRPPAGSEEAAERRGGGAGARSQRVHASQHFQTNSGTFHTPARAG
GSESGREATPILPLSLAQLCPAPPGLRSARRGPCSCAPGALPGHPGPRSQDKAMKPALLEVMRMNRICRMVLATCLGSFILVIFYFQSML
HPGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPK
RPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPA
EVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKN
VRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQ
IQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKIETYRLTFRANARARTDHGADIVSRPP

--------------------------------------------------------------

>16688_16688_4_CHST11-MAP4_CHST11_chr12_104851307_ENST00000303694_MAP4_chr3_47919013_ENST00000426837_length(amino acids)=668AA_BP=182
MERNEVAFGEKGEGPSDSHSGQRSGSGGGTTITARTPAARPATRQRRPPAGSEEAAERRGGGAGARSQRVHASQHFQTNSGTFHTPARAG
GSESGREATPILPLSLAQLCPAPPGLRSARRGPCSCAPGALPGHPGPRSQDKAMKPALLEVMRMNRICRMVLATCLGSFILVIFYFQSML
HPGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPK
RPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPA
EVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKN
VRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQ
IQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLCPGPPAGEEPAISEAAP

--------------------------------------------------------------

>16688_16688_5_CHST11-MAP4_CHST11_chr12_104851307_ENST00000547956_MAP4_chr3_47919013_ENST00000360240_length(amino acids)=668AA_BP=182
MERNEVAFGEKGEGPSDSHSGQRSGSGGGTTITARTPAARPATRQRRPPAGSEEAAERRGGGAGARSQRVHASQHFQTNSGTFHTPARAG
GSESGREATPILPLSLAQLCPAPPGLRSARRGPCSCAPGALPGHPGPRSQDKAMKPALLEVMRMNRICRMVLATCLGSFILVIFYFQSML
HPGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPK
RPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPA
EVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKN
VRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQ
IQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLCPGPPAGEEPAISEAAP

--------------------------------------------------------------

>16688_16688_6_CHST11-MAP4_CHST11_chr12_104851307_ENST00000547956_MAP4_chr3_47919013_ENST00000383737_length(amino acids)=599AA_BP=182
MERNEVAFGEKGEGPSDSHSGQRSGSGGGTTITARTPAARPATRQRRPPAGSEEAAERRGGGAGARSQRVHASQHFQTNSGTFHTPARAG
GSESGREATPILPLSLAQLCPAPPGLRSARRGPCSCAPGALPGHPGPRSQDKAMKPALLEVMRMNRICRMVLATCLGSFILVIFYFQSML
HPGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPK
RPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPA
EVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKN
VRSKVGSTENIKHQPGGGRVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGS

--------------------------------------------------------------

>16688_16688_7_CHST11-MAP4_CHST11_chr12_104851307_ENST00000547956_MAP4_chr3_47919013_ENST00000395734_length(amino acids)=651AA_BP=182
MERNEVAFGEKGEGPSDSHSGQRSGSGGGTTITARTPAARPATRQRRPPAGSEEAAERRGGGAGARSQRVHASQHFQTNSGTFHTPARAG
GSESGREATPILPLSLAQLCPAPPGLRSARRGPCSCAPGALPGHPGPRSQDKAMKPALLEVMRMNRICRMVLATCLGSFILVIFYFQSML
HPGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPK
RPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPA
EVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKN
VRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQ
IQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKIETYRLTFRANARARTDHGADIVSRPP

--------------------------------------------------------------

>16688_16688_8_CHST11-MAP4_CHST11_chr12_104851307_ENST00000547956_MAP4_chr3_47919013_ENST00000426837_length(amino acids)=668AA_BP=182
MERNEVAFGEKGEGPSDSHSGQRSGSGGGTTITARTPAARPATRQRRPPAGSEEAAERRGGGAGARSQRVHASQHFQTNSGTFHTPARAG
GSESGREATPILPLSLAQLCPAPPGLRSARRGPCSCAPGALPGHPGPRSQDKAMKPALLEVMRMNRICRMVLATCLGSFILVIFYFQSML
HPGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPK
RPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPA
EVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKN
VRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQ
IQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLCPGPPAGEEPAISEAAP

--------------------------------------------------------------

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Fusion Protein Functional Features


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:104851307/chr3:47919013)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CHST11

Q9NPF2

MAP4

Q9Y4K4

FUNCTION: Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Can also sulfate Gal residues in desulfated dermatan sulfate. Preferentially sulfates in GlcA->GalNAc unit than in IdoA->GalNAc unit. Does not form 4, 6-di-O-sulfated GalNAc when chondroitin sulfate C is used as an acceptor.FUNCTION: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. {ECO:0000269|PubMed:9038372}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

* Minus value of BPloci means that the break pointn is located before the CDS.
- Retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCHST11chr12:104851307chr3:47919013ENST00000303694+131_1639.333333333333336353.0Topological domainCytoplasmic
HgeneCHST11chr12:104851307chr3:47919013ENST00000303694+1317_3739.333333333333336353.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneMAP4chr12:104851307chr3:47919013ENST0000043426704248_5450100.0RegionNote=17 X 14 AA tandem repeats
TgeneMAP4chr12:104851307chr3:47919013ENST0000043935604248_5450100.0RegionNote=17 X 14 AA tandem repeats
TgeneMAP4chr12:104851307chr3:47919013ENST000003602407191023_1053666.33333333333341153.0RepeatNote=Tau/MAP 3
TgeneMAP4chr12:104851307chr3:47919013ENST000003602407191054_1085666.33333333333341153.0RepeatNote=Tau/MAP 4
TgeneMAP4chr12:104851307chr3:47919013ENST00000360240719923_953666.33333333333341153.0RepeatNote=Tau/MAP 1
TgeneMAP4chr12:104851307chr3:47919013ENST00000360240719992_1022666.33333333333341153.0RepeatNote=Tau/MAP 2
TgeneMAP4chr12:104851307chr3:47919013ENST000003957347181023_1053666.33333333333341136.0RepeatNote=Tau/MAP 3
TgeneMAP4chr12:104851307chr3:47919013ENST000003957347181054_1085666.33333333333341136.0RepeatNote=Tau/MAP 4
TgeneMAP4chr12:104851307chr3:47919013ENST00000395734718923_953666.33333333333341136.0RepeatNote=Tau/MAP 1
TgeneMAP4chr12:104851307chr3:47919013ENST00000395734718992_1022666.33333333333341136.0RepeatNote=Tau/MAP 2
TgeneMAP4chr12:104851307chr3:47919013ENST00000434267041023_10530100.0RepeatNote=Tau/MAP 3
TgeneMAP4chr12:104851307chr3:47919013ENST00000434267041054_10850100.0RepeatNote=Tau/MAP 4
TgeneMAP4chr12:104851307chr3:47919013ENST0000043426704248_2610100.0RepeatNote=1
TgeneMAP4chr12:104851307chr3:47919013ENST0000043426704262_2750100.0RepeatNote=2
TgeneMAP4chr12:104851307chr3:47919013ENST0000043426704276_2890100.0RepeatNote=3
TgeneMAP4chr12:104851307chr3:47919013ENST0000043426704290_3030100.0RepeatNote=4
TgeneMAP4chr12:104851307chr3:47919013ENST0000043426704304_3170100.0RepeatNote=5
TgeneMAP4chr12:104851307chr3:47919013ENST0000043426704318_3310100.0RepeatNote=6
TgeneMAP4chr12:104851307chr3:47919013ENST0000043426704332_3450100.0RepeatNote=7
TgeneMAP4chr12:104851307chr3:47919013ENST0000043426704346_3510100.0RepeatNote=8%3B truncated
TgeneMAP4chr12:104851307chr3:47919013ENST0000043426704352_3770100.0RepeatNote=26 residues 1
TgeneMAP4chr12:104851307chr3:47919013ENST0000043426704378_4030100.0RepeatNote=26 residues 2
TgeneMAP4chr12:104851307chr3:47919013ENST0000043426704408_4210100.0RepeatNote=9
TgeneMAP4chr12:104851307chr3:47919013ENST0000043426704422_4330100.0RepeatNote=10
TgeneMAP4chr12:104851307chr3:47919013ENST0000043426704434_4470100.0RepeatNote=11
TgeneMAP4chr12:104851307chr3:47919013ENST0000043426704448_4610100.0RepeatNote=12
TgeneMAP4chr12:104851307chr3:47919013ENST0000043426704462_4750100.0RepeatNote=13
TgeneMAP4chr12:104851307chr3:47919013ENST0000043426704476_4890100.0RepeatNote=14
TgeneMAP4chr12:104851307chr3:47919013ENST0000043426704490_5030100.0RepeatNote=15
TgeneMAP4chr12:104851307chr3:47919013ENST0000043426704504_5170100.0RepeatNote=16
TgeneMAP4chr12:104851307chr3:47919013ENST0000043426704532_5450100.0RepeatNote=17
TgeneMAP4chr12:104851307chr3:47919013ENST0000043426704923_9530100.0RepeatNote=Tau/MAP 1
TgeneMAP4chr12:104851307chr3:47919013ENST0000043426704992_10220100.0RepeatNote=Tau/MAP 2
TgeneMAP4chr12:104851307chr3:47919013ENST00000439356041023_10530100.0RepeatNote=Tau/MAP 3
TgeneMAP4chr12:104851307chr3:47919013ENST00000439356041054_10850100.0RepeatNote=Tau/MAP 4
TgeneMAP4chr12:104851307chr3:47919013ENST0000043935604248_2610100.0RepeatNote=1
TgeneMAP4chr12:104851307chr3:47919013ENST0000043935604262_2750100.0RepeatNote=2
TgeneMAP4chr12:104851307chr3:47919013ENST0000043935604276_2890100.0RepeatNote=3
TgeneMAP4chr12:104851307chr3:47919013ENST0000043935604290_3030100.0RepeatNote=4
TgeneMAP4chr12:104851307chr3:47919013ENST0000043935604304_3170100.0RepeatNote=5
TgeneMAP4chr12:104851307chr3:47919013ENST0000043935604318_3310100.0RepeatNote=6
TgeneMAP4chr12:104851307chr3:47919013ENST0000043935604332_3450100.0RepeatNote=7
TgeneMAP4chr12:104851307chr3:47919013ENST0000043935604346_3510100.0RepeatNote=8%3B truncated
TgeneMAP4chr12:104851307chr3:47919013ENST0000043935604352_3770100.0RepeatNote=26 residues 1
TgeneMAP4chr12:104851307chr3:47919013ENST0000043935604378_4030100.0RepeatNote=26 residues 2
TgeneMAP4chr12:104851307chr3:47919013ENST0000043935604408_4210100.0RepeatNote=9
TgeneMAP4chr12:104851307chr3:47919013ENST0000043935604422_4330100.0RepeatNote=10
TgeneMAP4chr12:104851307chr3:47919013ENST0000043935604434_4470100.0RepeatNote=11
TgeneMAP4chr12:104851307chr3:47919013ENST0000043935604448_4610100.0RepeatNote=12
TgeneMAP4chr12:104851307chr3:47919013ENST0000043935604462_4750100.0RepeatNote=13
TgeneMAP4chr12:104851307chr3:47919013ENST0000043935604476_4890100.0RepeatNote=14
TgeneMAP4chr12:104851307chr3:47919013ENST0000043935604490_5030100.0RepeatNote=15
TgeneMAP4chr12:104851307chr3:47919013ENST0000043935604504_5170100.0RepeatNote=16
TgeneMAP4chr12:104851307chr3:47919013ENST0000043935604532_5450100.0RepeatNote=17
TgeneMAP4chr12:104851307chr3:47919013ENST0000043935604923_9530100.0RepeatNote=Tau/MAP 1
TgeneMAP4chr12:104851307chr3:47919013ENST0000043935604992_10220100.0RepeatNote=Tau/MAP 2

- Not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCHST11chr12:104851307chr3:47919013ENST00000303694+13124_13039.333333333333336353.0Nucleotide bindingPAPS
HgeneCHST11chr12:104851307chr3:47919013ENST00000303694+13186_19439.333333333333336353.0Nucleotide bindingPAPS
HgeneCHST11chr12:104851307chr3:47919013ENST00000549260+13124_1300348.0Nucleotide bindingPAPS
HgeneCHST11chr12:104851307chr3:47919013ENST00000549260+13186_1940348.0Nucleotide bindingPAPS
HgeneCHST11chr12:104851307chr3:47919013ENST00000303694+1338_35239.333333333333336353.0Topological domainLumenal
HgeneCHST11chr12:104851307chr3:47919013ENST00000549260+131_160348.0Topological domainCytoplasmic
HgeneCHST11chr12:104851307chr3:47919013ENST00000549260+1338_3520348.0Topological domainLumenal
HgeneCHST11chr12:104851307chr3:47919013ENST00000549260+1317_370348.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneMAP4chr12:104851307chr3:47919013ENST00000360240719248_545666.33333333333341153.0RegionNote=17 X 14 AA tandem repeats
TgeneMAP4chr12:104851307chr3:47919013ENST00000395734718248_545666.33333333333341136.0RegionNote=17 X 14 AA tandem repeats
TgeneMAP4chr12:104851307chr3:47919013ENST00000360240719248_261666.33333333333341153.0RepeatNote=1
TgeneMAP4chr12:104851307chr3:47919013ENST00000360240719262_275666.33333333333341153.0RepeatNote=2
TgeneMAP4chr12:104851307chr3:47919013ENST00000360240719276_289666.33333333333341153.0RepeatNote=3
TgeneMAP4chr12:104851307chr3:47919013ENST00000360240719290_303666.33333333333341153.0RepeatNote=4
TgeneMAP4chr12:104851307chr3:47919013ENST00000360240719304_317666.33333333333341153.0RepeatNote=5
TgeneMAP4chr12:104851307chr3:47919013ENST00000360240719318_331666.33333333333341153.0RepeatNote=6
TgeneMAP4chr12:104851307chr3:47919013ENST00000360240719332_345666.33333333333341153.0RepeatNote=7
TgeneMAP4chr12:104851307chr3:47919013ENST00000360240719346_351666.33333333333341153.0RepeatNote=8%3B truncated
TgeneMAP4chr12:104851307chr3:47919013ENST00000360240719352_377666.33333333333341153.0RepeatNote=26 residues 1
TgeneMAP4chr12:104851307chr3:47919013ENST00000360240719378_403666.33333333333341153.0RepeatNote=26 residues 2
TgeneMAP4chr12:104851307chr3:47919013ENST00000360240719408_421666.33333333333341153.0RepeatNote=9
TgeneMAP4chr12:104851307chr3:47919013ENST00000360240719422_433666.33333333333341153.0RepeatNote=10
TgeneMAP4chr12:104851307chr3:47919013ENST00000360240719434_447666.33333333333341153.0RepeatNote=11
TgeneMAP4chr12:104851307chr3:47919013ENST00000360240719448_461666.33333333333341153.0RepeatNote=12
TgeneMAP4chr12:104851307chr3:47919013ENST00000360240719462_475666.33333333333341153.0RepeatNote=13
TgeneMAP4chr12:104851307chr3:47919013ENST00000360240719476_489666.33333333333341153.0RepeatNote=14
TgeneMAP4chr12:104851307chr3:47919013ENST00000360240719490_503666.33333333333341153.0RepeatNote=15
TgeneMAP4chr12:104851307chr3:47919013ENST00000360240719504_517666.33333333333341153.0RepeatNote=16
TgeneMAP4chr12:104851307chr3:47919013ENST00000360240719532_545666.33333333333341153.0RepeatNote=17
TgeneMAP4chr12:104851307chr3:47919013ENST00000395734718248_261666.33333333333341136.0RepeatNote=1
TgeneMAP4chr12:104851307chr3:47919013ENST00000395734718262_275666.33333333333341136.0RepeatNote=2
TgeneMAP4chr12:104851307chr3:47919013ENST00000395734718276_289666.33333333333341136.0RepeatNote=3
TgeneMAP4chr12:104851307chr3:47919013ENST00000395734718290_303666.33333333333341136.0RepeatNote=4
TgeneMAP4chr12:104851307chr3:47919013ENST00000395734718304_317666.33333333333341136.0RepeatNote=5
TgeneMAP4chr12:104851307chr3:47919013ENST00000395734718318_331666.33333333333341136.0RepeatNote=6
TgeneMAP4chr12:104851307chr3:47919013ENST00000395734718332_345666.33333333333341136.0RepeatNote=7
TgeneMAP4chr12:104851307chr3:47919013ENST00000395734718346_351666.33333333333341136.0RepeatNote=8%3B truncated
TgeneMAP4chr12:104851307chr3:47919013ENST00000395734718352_377666.33333333333341136.0RepeatNote=26 residues 1
TgeneMAP4chr12:104851307chr3:47919013ENST00000395734718378_403666.33333333333341136.0RepeatNote=26 residues 2
TgeneMAP4chr12:104851307chr3:47919013ENST00000395734718408_421666.33333333333341136.0RepeatNote=9
TgeneMAP4chr12:104851307chr3:47919013ENST00000395734718422_433666.33333333333341136.0RepeatNote=10
TgeneMAP4chr12:104851307chr3:47919013ENST00000395734718434_447666.33333333333341136.0RepeatNote=11
TgeneMAP4chr12:104851307chr3:47919013ENST00000395734718448_461666.33333333333341136.0RepeatNote=12
TgeneMAP4chr12:104851307chr3:47919013ENST00000395734718462_475666.33333333333341136.0RepeatNote=13
TgeneMAP4chr12:104851307chr3:47919013ENST00000395734718476_489666.33333333333341136.0RepeatNote=14
TgeneMAP4chr12:104851307chr3:47919013ENST00000395734718490_503666.33333333333341136.0RepeatNote=15
TgeneMAP4chr12:104851307chr3:47919013ENST00000395734718504_517666.33333333333341136.0RepeatNote=16
TgeneMAP4chr12:104851307chr3:47919013ENST00000395734718532_545666.33333333333341136.0RepeatNote=17


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Fusion Protein-Protein Interaction


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)
GenePPI interactors


check button Protein-protein interactors based on sequence similarity (STRING)
GeneSTRING network
CHST11
MAP4


check button - Retained interactions in fusion protein (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost interactions due to fusion (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs to CHST11-MAP4


check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

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Related Diseases to CHST11-MAP4


check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource